Portable three-dimensional dose verification device for radiotherapy
By designing a portable three-dimensional dose verification device, using the probe moving component to move in the water along the beam direction, the problem of the inability to effectively verify the three-dimensional dose distribution of the beam in the prior art is solved, and the support for the beam detection of multi-directional irradiation in Gantry treatment is achieved, and the treatment accuracy and radiotherapy efficiency are improved.
Patent Information
- Application Number
- CN202421017353.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-11
- Publication Date
- 2025-02-28
- Estimated Expiration
- 2034-05-11
AI Technical Summary
The existing water tank device can only measure the two-dimensional depth dose curve and field distribution, and cannot effectively verify the three-dimensional dose distribution of the beam. Especially in rotary Gantry treatment, it cannot meet the beam detection needs of multi-directional irradiation, which affects the treatment accuracy.
A portable three-dimensional dose verification device is designed, using two probes organically combined with a three-dimensional water tank. The probe moving component drives the probe to move linearly in the water along the direction of the beam flow incident, achieving rapid verification of the three-dimensional dose distribution of the beam flow.
It realizes rapid verification of the three-dimensional beam dose distribution, meets the beam detection needs of multi-directional irradiation in Gantry treatment, and improves the accuracy of treatment plans and radiotherapy efficiency.
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Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of medical equipment, in particular to a portable three-dimensional dose verification device for proton and heavy ion radiotherapy. Background Art
[0002] In the 21st century, with the rapid development of nuclear science and accelerator technology, particle beam radiotherapy for tumors is one of the main methods and means of tumor treatment and control. Proton and heavy ion are an advanced technology in radiotherapy. Compared with traditional radiotherapy, proton and heavy ion therapy represents the highest technology and future trend of radiotherapy.
[0003] In recent years, as the requirements for accelerators in radiotherapy continue to increase, multi-angle adjustable radiotherapy is required. In radiotherapy, the rotating Gantry that can deliver beams at any angle is the most ideal ion beam therapy terminal delivery system for conformal therapy, and for this reason, the rotating Gantry treatment system has been vigorously developed.
[0004] In order to ensure that patients are treated accurately as planned and to improve the cure and control rates of tumors, a substitute similar to human tissue is required to perform clinical measurements of beam radiation during radiotherapy. Currently, the most widely used clinical measurement of radiation around the world is to use a water tank to simulate human tissue for detection, and water tanks play an important role in the radiotherapy process. Existing water tanks use sensor probes such as ionization chambers to complete ion beam detection at different positions and depths in the water tank, simulate the internal structure of the human body, and provide beam doses at different positions and depths, thereby accurately guiding treatment plans and programs.
[0005] In the process of formulating proton and carbon ion tumor treatment plans, since the beam parameters of different treatment devices are different, it is necessary to set the corresponding beam parameters according to the specific treatment device to accurately simulate the actual beam state in order to ensure the accuracy of the treatment plan. In both the formulation of the treatment plan and the evaluation of the treatment effect, it is necessary to adjust the parameters to ensure that the model and the actual beam are as close as possible, so that the three-dimensional dose distribution can be accurately estimated.
[0006] At present, most treatment devices rely on water tanks that can only measure two-dimensional depth dose curves and field distribution, etc., while for the verification of the three-dimensional dose of the beam, it is necessary to use a water tank scanning mechanism to drive the finger-shaped ionization chamber to scan point by point in the water, and the overall verification efficiency is low. Especially for devices where the beam shakes unexpectedly, when the water tank scanning mechanism drives the finger-shaped ionization chamber probe to scan point by point in the water tank, it cannot accurately reflect the true distribution of the beam, which directly affects the treatment accuracy. For example, a macro pulse cycle of the beam is 8s, and the scanning process of the finger-shaped ionization chamber is 30-40 minutes. The beam dose cannot be accurately measured within the beam cycle, and only local points can be verified. In addition, the existing water tank is only suitable for beam terminals with fixed angle irradiation, and all of them are open-top structures, and the side walls of the water tank are provided with horizontal incidence windows or 45° incidence windows. This type of water tank is not suitable for placement at different angles, and can only meet horizontal irradiation, vertical irradiation and 45-degree irradiation. It cannot meet the beam measurement needs in the new rotational Gantry treatment, which seriously restricts the formulation of treatment plans in Gantry treatment. Utility Model Content
[0007] The utility model aims to solve at least one of the technical problems existing in the prior art. To this end, the utility model provides a portable three-dimensional dose verification device for radiotherapy, which uses two probes and a three-dimensional water tank to organically combine to achieve rapid verification of the three-dimensional dose distribution of the beam, provide parameter basis for treatment planning, and improve QA (Quality Assurance) efficiency.
[0008] In order to achieve the above purpose, the utility model adopts the following technical solutions:
[0009] A portable three-dimensional dose verification device for radiotherapy, comprising a water tank assembly, a first measuring probe and a probe moving assembly; the water tank assembly comprises a box body and a box cover, the box body and the box cover are sealed and connected to form a sealed space for accommodating water, and a first incident window for beam flow to pass through is arranged on the front side of the box body; the probe moving assembly is arranged inside the box body, the first measuring probe is arranged on the probe moving assembly, and the probe moving assembly is configured to drive the first measuring probe to move linearly in the water along the incident direction of the beam flow, so as to realize the dose distribution measurement of the first measuring probe at different positions.
[0010] Preferably, the probe moving assembly comprises: a screw-guide rail slider mechanism, which is fixed in the box along the length direction of the box, and the first measuring probe is installed on the action end of the screw-guide rail slider mechanism; a drive motor, which is arranged outside the box, and the drive motor is connected to the screw-guide rail slider mechanism through a magnetic fluid seal and a coupling.
[0011] Preferably, a second measuring probe is further arranged at the front end of the first incident window of the box body, for cooperating with the first measuring probe to realize rapid verification of the three-dimensional dose distribution of the beam.
[0012] Preferably, two valves are arranged on the side of the box body for injecting or draining water into the sealed space of the box body.
[0013] Preferably, a handle is provided on the box cover.
[0014] Preferably, the first measuring probe and the second measuring probe are both two-dimensional profile measurement stripe ionization chamber probes or matrix ionization chamber probes.
[0015] Preferably, the first measuring probe comprises a striping probe and a watertight shell arranged outside the striping probe, a second incident window and an exit window are respectively arranged on the front and rear sides of the watertight shell, a sealing tube is arranged on the lower side of the watertight shell, a flexible signal lead-out plate is passed through the sealing tube, and a through-wall sealing hole is arranged on the side panel of the box body, which is used to cooperate with the sealing tube to lead the signal of the striping probe to the outside of the box body; a detachable sealing flange is also connected to the lower side of the watertight shell through a rubber seal to facilitate the installation and maintenance of the striping probe.
[0016] Preferably, a shielding shell is provided outside the signal lead-out board located outside the box body, and the shielding shell is used to shield noise and facilitate the fixation of the signal lead-out board connector and the plugging of external electronics.
[0017] Preferably, the first incident window is a pressing plate made of PMMA material, which is connected to the box body in a rubber sealing manner, and a pit is arranged inside the first incident window of the box body.
[0018] Preferably, the first incident window is provided with engraved lines on the outside, suitable for alignment by laser.
[0019] The utility model adopts the above technical solution, which has the following advantages:
[0020] 1. The portable three-dimensional dose verification device provided by the utility model has a compact and small structure, high working efficiency, and adopts a sealed structure to meet the requirements of placing the box at different angles. In addition to meeting the requirements of traditional treatment angles, it can also meet the beam detection requirements in multi-directional irradiation in Gantry treatment, saving beam time and improving radiotherapy efficiency.
[0021] 2. The portable three-dimensional dose verification device provided by the utility model, wherein the first measuring probe and the second measuring probe are both two-dimensional profile measurement stripe ionization chamber probes or matrix ionization chamber probes. The two-dimensional profile measurement stripe ionization chamber probes can measure the two-dimensional dose distribution of the probe at a specific depth at one time. As the probe moves in the water, the three-dimensional dose distribution parameters of the beam radiation field can be conveniently and accurately measured.
[0022] 3. The portable three-dimensional dose verification device provided by the utility model has a first measuring probe including a striping probe and an external watertight shell. An incident window and an exit window are arranged on the front and rear sides of the sealed shell. A flexible signal lead-out sealing tube is also arranged. The striping probe is connected to external electronics through the sealing tube. The sealing tube can ensure the watertight output of the signal while providing working gas to the inside of the striping probe.
[0023] 4. The utility model arranges the depth direction drive motor outside the box, which can greatly reduce the size and weight of the box. At the same time, the depth direction drive motor can select a servo motor with higher precision and an encoder to achieve precise position feedback of the moving direction of the first measuring probe and synchronize the acquisition of the beam signal and the position signal, thereby realizing rapid and accurate verification of the beam dose. BRIEF DESCRIPTION OF THE DRAWINGS
[0024] By reading the detailed description of the preferred embodiment below, various other advantages and benefits will become clear to those of ordinary skill in the art. The accompanying drawings are only used for the purpose of illustrating the preferred embodiment and are not considered to be limiting of the present invention. The same reference numerals are used throughout the accompanying drawings to represent the same components. In the accompanying drawings:
[0025] Figure 1 This is a front view of the overall assembly of a portable three-dimensional dose verification device provided by a preferred embodiment of the utility model;
[0026] Figure 2 It is a schematic diagram of the internal structure of the portable three-dimensional dose verification device provided by this embodiment of the utility model;
[0027] Figure 3 It is a structural schematic diagram of a water tank assembly provided by a preferred embodiment of the utility model;
[0028] Figure 4 It is a structural schematic diagram of a first measuring probe provided by a preferred embodiment of the utility model;
[0029] Figure 5 This is a structural schematic diagram of a box provided by a preferred embodiment of the utility model;
[0030] Figure 6 It is a schematic diagram of the portable three-dimensional dose verification device of the utility model when it is placed horizontally;
[0031] Figure 7 It is a schematic diagram of the portable three-dimensional dose verification device of the utility model when it is placed vertically.
[0032] The reference numerals in the figures are as follows:
[0033] 1-water tank assembly; 2-first measuring probe; 3-probe moving assembly; 4-second measuring probe;
[0034] 11-box body; 12-box cover; 13-first incident window; 14-valve; 15-handle; 16-wall sealing hole; 17-pit;
[0035] 21-strip probe; 22-watertight housing; 23-second incident window; 24-sealing tube; 25-signal lead-out board; 26-sealing flange; 27-shielding shell;
[0036] 31-screw-guide rail slider mechanism; 32-driving motor; 33-magnetic fluid seal; 34-coupling. DETAILED DESCRIPTION
[0037] In order to make the purpose, technical solution and advantages of the utility model clearer, the specific embodiments of the utility model are further described below in conjunction with the accompanying drawings. Although the exemplary embodiments of the utility model are shown in the accompanying drawings, it should be understood that the utility model can be implemented in various forms and should not be limited by the embodiments described here. On the contrary, these embodiments are provided to enable a more thorough understanding of the utility model and to fully convey the scope of the utility model to those skilled in the art.
[0038] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.
[0039] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of the present utility model, the meaning of "plurality" is more than two, unless otherwise clearly and specifically defined.
[0040] In the present invention, unless otherwise clearly specified and limited, the terms "install", "connect", "connect", "fix" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
[0041] In the present utility model, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being "above", "above" or "above" a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being "below", "below" or "below" a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.
[0042] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the utility model. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, without contradiction.
[0043] The portable three-dimensional dose verification device for radiotherapy provided by the utility model includes a water tank assembly, a first measuring probe and a probe moving assembly; the water tank assembly includes a box body and a box cover, the box body and the box cover are sealed and connected to form a sealed space for accommodating water, and a first incident window for beam flow to pass through is arranged on the front side of the box body; the probe moving assembly is arranged inside the box body, the first measuring probe is arranged on the probe moving assembly, and the probe moving assembly is configured to drive the first measuring probe to move linearly along the incident direction of the beam in the water, so as to realize the dose distribution measurement of the first measuring probe at different positions. The portable three-dimensional dose verification device for radiotherapy provided by the utility model has a compact structure, is small, and has high working efficiency, and adopts a sealed structure to meet the requirements of placing the box body at different angles. In addition to meeting the requirements of traditional treatment angles, it can also meet the beam detection requirements in multi-directional irradiation in Gantry treatment, save beam time, and improve radiotherapy efficiency.
[0044] Below, a portable three-dimensional dose verification device for radiotherapy provided by a preferred embodiment of the utility model is described in detail with reference to the accompanying drawings.
[0045] See also Figures 1 to 3 A preferred embodiment of the utility model provides a portable three-dimensional dose verification device for radiotherapy, including a water tank component 1, a first measuring probe 2 and a probe moving component 3.
[0046] The water tank assembly 1 includes a box body 11 and a box cover 12, the box body 11 and the box cover 12 are sealed and connected to form a sealed space for accommodating water, and a first incident window 13 for the beam to pass through is arranged at the front side of the box body 11. The probe moving assembly 3 is arranged inside the box body 11, and the first measuring probe 2 is arranged on the probe moving assembly 3. The probe moving assembly 3 is configured to drive the first measuring probe 2 to move linearly along the incident direction of the beam in the water, so as to realize the dose distribution measurement of the first measuring probe 2 at different positions.
[0047] In the above embodiment, preferably, the probe moving assembly 3 includes a screw-guide slider mechanism 31 and a drive motor 32, the screw-guide slider mechanism 31 is fixed in the box body 11 along the length direction of the box body 11, and the screw-guide slider mechanism 31 is connected to the drive motor 32 outside the box body 11 through a magnetic fluid seal 33 and a coupling 34; the first measuring probe 2 is installed on the action end of the screw-guide slider mechanism 31. Through the above arrangement, the drive motor 32 can drive the first measuring probe 2 to move linearly along the beam incident direction (i.e., the depth direction of the water). In addition, arranging the drive motor 32 outside the box body 11 can greatly reduce the size and weight of the box body 11, and at the same time, the drive motor 32 can select a servo motor with higher precision and an encoder to achieve precise feedback of the position of the moving direction of the first measuring probe 2, thereby meeting the higher movement precision requirement of the probe to the beam direction.
[0048] In the above embodiment, preferably, a second measuring probe 4 is further provided at the front end of the first incident window 13 of the box 11 for cooperating with the first measuring probe 2 to realize rapid verification of the three-dimensional dose distribution of the beam.
[0049] In the above embodiment, preferably, two valves 14 are provided on the side of the box body 11 for injecting or draining water into the sealed space of the box body 11 .
[0050] In the above embodiment, preferably, a handle 15 is provided on the box cover 12 to facilitate the transportation of the dose verification device.
[0051] In the above embodiments, preferably, please refer to Figure 4 The first measuring probe 2 and the second measuring probe 4 are both two-dimensional profile measuring stripe ionization chamber probes or matrix ionization chamber probes. The first measuring probe 2 includes a stripe probe 21 and a watertight shell 22 arranged outside the stripe probe 21. The watertight shell 22 ensures that the probe works completely sealed in water. The front and rear sides of the watertight shell 22 are respectively provided with a second incident window 23 and an exit window (similar to the second incident window 23, on the rear side of the watertight shell 22). A sealing tube 24 is arranged on the lower side of the watertight shell 22. A flexible signal lead-out plate 25 is inserted into the sealing tube 24. A through-wall sealing hole 16 is arranged on the side plate of the box body 11 (please refer to Figure 3 ), which is used to cooperate with the sealing tube 24 to lead the signal of the striping probe 21 to the outside of the box 11. The sealing tube 24 can ensure the watertight output of the signal and can also provide working gas such as air or nitrogen to the inside of the striping probe 21. The lower side of the watertight shell 22 is also connected to a detachable sealing flange 26 through a rubber seal to facilitate the installation and maintenance of the striping probe 21. At the same time, a shielding shell 27 is also provided on the outside of the signal lead-out board 25 located outside the box 11 (see Figure 1 ), the shielding shell 27 can effectively shield noise, and at the same time facilitate the fixation of the connector of the signal lead-out board 25 and the plug-in of external electronics.
[0052] In the above embodiments, preferably, please refer to Figure 5 The first incident window 13 is a PMMA pressure plate connected to the box body 11 in a rubber sealing manner, and a pit 17 is provided inside the first incident window 13 of the box body 11, which can effectively solve the problem of non-zero gap between the water surface and the inside of the first incident window 13 when the water tank assembly 1 is placed vertically, ensuring that the water is always in direct contact with the first incident window 13. At the same time, the first incident window 13 is provided with a scribed line on the outside to facilitate alignment by laser.
[0053] When using the portable three-dimensional dose verification device for radiotherapy provided by the utility model for measurement verification, first fill the box 11 with water. Due to the sealed setting of the water tank assembly 1, the entire verification device can be placed horizontally or vertically, and can also be installed on brackets at different angles to achieve multi-angle dose verification. When placed horizontally, the verification device can be used for measurement verification of horizontal beams (see Figure 6 ), when placed vertically, the verification device can be used for vertical beam current measurement verification (see Figure 7 ).
[0054] During the measurement verification process, the beam enters the interior of the box 11 through the first incident window 13, wherein the first measuring probe 2 and the second measuring probe 4 are both on the incident path of the beam, and the two probes are of the same type, so the first measuring probe 2 and the second measuring probe 4 will synchronously measure the incident beam, and at the same time, the probe moving assembly 3 drives the first measuring probe 2 to move in the depth direction along the beam direction, thereby realizing the dose distribution measurement of the first measuring probe 2 at different positions. At this time, the first measuring probe 2 can obtain measurement data at different water depths relative to the second measuring probe 4, and realize the rapid acquisition of beam data by the measuring device; when the subsequent measurement data is collated, because the second measuring probe 4 is located at the first incident window 13, the first measuring probe 2 needs to perform normalized parameter processing on the beam intensity, position, and horizontal and vertical projection parameters relative to the second measuring probe 4, so as to improve the accuracy of three-dimensional dose modeling, provide accurate parameter basis for the treatment effect evaluation system, and improve QA efficiency.
[0055] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application, rather than to limit them; although the present application has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein by equivalents; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present application, and they should all be included in the scope of the claims and specification of the present application. In particular, as long as there is no structural conflict, the various technical features mentioned in the various embodiments can be combined in any way. The present application is not limited to the specific embodiments disclosed herein, but includes all technical solutions that fall within the scope of the claims.
Claims
1. A portable three-dimensional dose verification device for radiotherapy, characterized in that: It includes a water tank assembly, a first measuring probe and a probe moving assembly; The water tank assembly includes a tank body and a tank cover, the tank body and the tank cover are sealingly connected to form a sealed space for accommodating water, and a first incident window for the beam to pass through is arranged on the front side of the tank body; the probe moving assembly is arranged inside the tank body, and the first measuring probe is arranged on the probe moving assembly, and the probe moving assembly is configured to drive the first measuring probe to move linearly along the incident direction of the beam in water, so as to realize dose distribution measurement of the first measuring probe at different positions.
2. The portable three-dimensional dose verification device for radiotherapy according to claim 1, characterized in that: The probe moving assembly comprises: A lead screw-guide rail slider mechanism is fixed in the box body along the length direction of the box body, and the first measuring probe is installed on the action end of the lead screw-guide rail slider mechanism; The drive motor is arranged outside the box body, and the drive motor is transmission-connected to the lead screw-guide rail slider mechanism through a magnetic fluid seal and a coupling.
3. The portable three-dimensional dose verification device for radiotherapy according to claim 1, characterized in that: A second measuring probe is also arranged at the front end of the first incident window of the box body, and is used to cooperate with the first measuring probe to realize rapid verification of the three-dimensional dose distribution of the beam.
4. The portable three-dimensional dose verification device for radiotherapy according to claim 1, characterized in that: Two valves are arranged on the side of the box body for injecting or draining water into the sealed space of the box body.
5. The portable three-dimensional dose verification device for radiotherapy according to claim 1, characterized in that: The box cover is provided with a handle.
6. The portable three-dimensional dose verification device for radiotherapy according to claim 3, characterized in that: The first measuring probe and the second measuring probe are both two-dimensional profile measurement stripe ionization chamber probes or matrix ionization chamber probes.
7. The portable three-dimensional dose verification device for radiotherapy according to claim 6, characterized in that: The first measuring probe includes a striping probe and a watertight shell arranged outside the striping probe, a second incident window and an exit window are respectively arranged on the front and rear sides of the watertight shell, a sealing tube is arranged on the lower side of the watertight shell, a flexible signal lead-out plate is passed through the sealing tube, and a through-wall sealing hole is arranged on the side panel of the box body, which is used to cooperate with the sealing tube to lead the signal of the striping probe to the outside of the box body; the lower side of the watertight shell is also connected with a detachable sealing flange through a rubber seal to facilitate the installation and maintenance of the striping probe.
8. The portable three-dimensional dose verification device for radiotherapy according to claim 7, characterized in that: A shielding shell is also provided outside the signal lead-out board located outside the box body, and the shielding shell is used to shield noise and facilitate the fixation of the signal lead-out board connector and the plugging of external electronics.
9. The portable three-dimensional dose verification device for radiotherapy according to any one of claims 1 to 8, characterized in that: The first incident window is a pressing plate made of PMMA material connected to the box body in a rubber sealing manner, and a pit is arranged inside the first incident window of the box body.
10. The portable three-dimensional dose verification device for radiotherapy according to any one of claims 1 to 8, characterized in that: The first incident window is provided with engraved lines on the outside, which are suitable for alignment by laser.