Intravenous self-administration cannula

Abstract

The utility model discloses a vein self-administration intubation tube which comprises a catheter which is in an L-shaped bent shape and is provided with a horizontal part and a vertical part. The connector is arranged on the outer side of the vertical part in a sleeving manner; one end of the hose is a connecting end which is hermetically connected with the catheter, and the other end of the hose is an inserting end; the gasket is arranged on the outer side of the connector and the outer side of the guide pipe in a sleeved mode, a limiting groove extending in the horizontal direction is formed in the gasket, and the horizontal part and the connecting position of the horizontal part and the hose are arranged in the limiting groove. The limiting groove tends to be gradually folded inwards from the end opening of the limiting groove till the groove width of the limiting groove is consistent with the outer diameter of the hose. Compared with the prior art, the utility model is not easy to bend and block.

Description

Technical Field

[0001] The utility model relates to the field of medical instruments, in particular to a cannula for intravenous self-medication. Background Art

[0002] Intravenous self-administration is one of the most widely used animal models in drug addiction research. In this model, animals actively press the plate or nose touch to obtain drugs entering the body from the jugular vein, completing effective intravenous self-administration behavior. At the same time, intravenous self-administration experiments generally last for several weeks or even months. Therefore, the success rate, stability and availability of intravenous cannulation surgery are more important in whether animals can maintain effective self-administration behavior for a long time, which is related to the patency of the cannulation catheter and whether effective drug administration can be achieved.

[0003] Intravenous self-administration can be achieved in a variety of animals, including rats, mice, primates, cats, dogs, etc. Rats are commonly used as experimental animals for physiological, pharmacological, and pharmacokinetic studies. At the same time, mice have a larger range of genetic manipulation and faster recovery after surgery, making them more useful animals for experimental research in future intravenous self-administration experiments. However, the jugular vein of mice is extremely thin, and cannulation is very difficult, which can easily lead to a long cannulation time, thereby prolonging the operation time. Mice are small in size, and a slight bleeding can easily cause excessive blood loss or death in mice. At the same time, the unreasonable design of the surgical cannula and the low degree of cleanliness after surgery can easily lead to catheter blockage, increase the risk of animal infection, and lead to leakage and experimental failure. Most of the cannulas required for jugular vein cannulation surgery are imported finished products. Their high prices and the lack of domestic agents have led to procurement difficulties, greatly limiting the application of cannulas in China.

[0004] To this end, the applicant previously disclosed a "Venous Self-Administration Cannula" (authorization announcement number CN106725990B), application number CN201611242899.3. Although the cannula disclosed in the patent has the advantages of convenient production and manufacturing, easy availability of materials, and low manufacturing cost, it has the following shortcomings:

[0005] First, given that mice are much smaller than rats, the originally designed gasket was too large. Not only could it serve as a foreign object and cause infection and ulceration in the back wound, but the larger gasket would also affect the mice's daily activities.

[0006] Second, mice have thinner skin than rats. Too thin a gasket can cause new wounds on the back skin, which can lead to wound ulceration, gasket detachment, tube leakage, and other problems, affecting the drug delivery process.

[0007] Third, after surgical ligation, scratching by mice can easily cause the back sutures to loosen, affecting wound healing and gasket fixation, and thus affecting the drug administration process;

[0008] Fourth, the effective period is short. The cannula will leak after 4-6 days. The self-administration period is 14 days, so the cannula on one side must be maintained for at least 7-10 days.

[0009] Fifth, the silicone hose fixing method in the original patent has defects. When the hose is not placed in the appropriate position, the incorrect bending of the hose may cause the hose to be blocked, which may require a second surgery on the mouse and seriously affect the continuity of drug administration.

[0010] Therefore, the existing drug administration cannula needs to be improved. Utility Model Content

[0011] The technical problem to be solved by the utility model is to provide a venous self-administration cannula which is not easy to be blocked in view of the above technical status.

[0012] The technical solution adopted by the utility model to solve the above technical problems is: a cannula for intravenous self-administration, comprising:

[0013] The conduit is bent in an "L" shape and has a horizontal portion and a vertical portion;

[0014] A connector, sleeved on the outside of the vertical portion; and

[0015] A hose, one end of which is a connection end, the connection end is sealed and connected to the aforementioned catheter, and the other end is an insertion end; characterized in that it also includes:

[0016] The gasket is sleeved on the outer side of the aforementioned connector and the conduit, and a limiting groove extending in the horizontal direction is provided in the gasket, so that the horizontal part and the connection between the horizontal part and the hose are arranged in the limiting groove; the limiting groove tends to gradually converge from the end of the limiting groove inward until the groove width of the limiting groove is consistent with the outer diameter of the hose.

[0017] In order to save material and fix the connector and the conduit, preferably, the gasket includes a supporting portion and a column portion with a protrusion arranged on the supporting portion, the bottom of the connector is accommodated on the column portion, the limiting groove is arranged in the supporting portion, and the horizontal portion is arranged in the supporting portion.

[0018] For sealing connection, preferably, the inner diameter of the hose is matched with the outer diameters of both the vertical portion and the horizontal portion of the conduit, and the connecting section of the conduit is sealingly connected to the conduit.

[0019] Preferably, the connector is sleeved on the outside of the middle portion of the vertical portion, the end of the connecting end of the conduit is disposed in the connector, and the conduit is sealed and connected to the vertical portion.

[0020] To facilitate insertion, preferably, an oblique cut is formed at the end of the insertion end.

[0021] In order to fix the hose in the blood vessel, preferably, the hose is provided with a silicone ball that can be implanted in the blood vessel.

[0022] In order to reduce the wear on the hose, preferably, the contour of the limiting groove is in an arc shape.

[0023] Compared with the prior art, the advantages of the utility model are: a limiting groove is provided in the gasket, which tends to gradually converge from the port inward, and the connection between the hose and the catheter is located in the limiting groove. The hose near the connection can be bent in the limiting groove, but is restricted by the side wall of the limiting groove. Therefore, the limiting groove provides a correct bending path for the hose, and the hose is not easy to be blocked. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 It is a structural schematic diagram of an embodiment;

[0025] Figure 2 is a three-dimensional cross-sectional view of an embodiment;

[0026] Figure 3 is a schematic diagram of a gasket in an embodiment;

[0027] Figure 4 for Figure 3 Sectional view of AA. DETAILED DESCRIPTION

[0028] The present invention will be described in further detail below in conjunction with the accompanying drawings.

[0029] like Figure 1-4 The preferred embodiment of the utility model is shown in FIG. 1 . The intravenous self-administration cannula comprises a catheter 1 , a connector 2 , a hose 3 , a gasket 4 and a silicone ball 5

[0030] The conduit 1 is bent in an "L" shape and has a horizontal portion 11 and a vertical portion 12;

[0031] The connector 2 is sleeved on the outside of the middle part of the vertical part 12, and the end of the connecting end a of the catheter 1 is arranged in the connector 2, and the catheter 1 is sealed and connected to the vertical part 12. The connector 2 is provided with an external thread. The end of the vertical part 12 of the catheter 1 is also equipped with a catheter cap (not shown in the figure), and the catheter cap is formed with an internal thread, which matches the external thread of the connector 2. The catheter cap is opened when the drug is administered and installed after the drug administration is completed.

[0032] One end of the hose 3 is a connection end a, which is sealed and connected to the aforementioned catheter 1, and the other end is an insertion end b; the end of the insertion end b forms an oblique cut. The inner diameter of the hose 3 is adapted to the outer diameters of the vertical portion 12 and the horizontal portion 11 of the catheter 1, so that the connection section of the catheter 1 is sealed and connected to the catheter 1. The hose 3 can be a silicone tube; the hose 3 is provided with a silicone ball 5 that can be implanted in a blood vessel.

[0033] The gasket 4 is sleeved on the outside of the connector 2 and the conduit 1. A limit groove 41 extending in the horizontal direction is provided in the gasket 4. The horizontal portion 11 and the connection between the horizontal portion 11 and the hose 3 are arranged in the limit groove 41. The limit groove 41 gradually converges from the end of the limit groove 41 to the inside until the groove width of the limit groove 41 is consistent with the outer diameter of the hose 3. The contour of the limit groove 41 is in an arc shape. The gasket 4 includes a support portion 42 and a column portion 43 protruding from the support portion 42. The bottom of the connector 2 is accommodated on the column portion 43. The limit groove 41 is arranged on the support portion 42 so that the horizontal portion 11 is arranged in the support portion 42. The top view of the supporting part of the gasket is an ellipse with a long diameter of 1 cm and a short diameter of 0.6 cm. The gasket is small in size and the wound after surgery is small, so the gasket is not easy to slip out. After the surgical ligation, the operator can stick a silicone disc on the suture to cover the suture to prevent the mouse from scratching, thereby extending the effective period of the intravenous self-administration catheter.

[0034] The administration process of this embodiment is as follows:

[0035] A small incision was made on the left / right chest of the mouse, and the opening was opened with scissors. The skin and muscle layers were bluntly separated with scissors to pass the tube all over the back; the muscle layer was separated with scissors (separated along the direction of the jugular vein) until the blood vessels were seen, and then the blood vessels were subdivided with scissors on both sides; the blood vessels were clamped with toothless forceps, and the muscle layer under the blood vessels was passed through with arrow surgical forceps, and marked with non-absorbable sutures. The back was opened, the skin and muscle layers were separated, the gasket 4 was implanted, and the flexible tube 3 was clamped with an elbow needle holder and passed through the subcutaneous tissue; the jugular vein was supported with blunt curved forceps, and a small incision was made with fine scissors, and the flexible tube 3 was inserted along the blood vessels. The jugular vein was sutured on both sides of the silicone ball 5.

Claims

1. A cannula for intravenous self-administration, comprising: The conduit (1) is bent in an L-shape and has a horizontal portion (11) and a vertical portion (12); A connecting head (2) is sleeved on the outside of the vertical portion (12); and A hose (3), one end of which is a connection end (a), the connection end (a) being sealed and connected to the aforementioned catheter (1), and the other end of which is an insertion end (b); characterized in that it also includes: A gasket (4) is sleeved on the outer sides of the aforementioned connector (2) and the conduit (1); a limiting groove (41) extending in the horizontal direction is provided in the gasket (4); the aforementioned horizontal portion (11) and the connection between the horizontal portion (11) and the hose (3) are arranged in the limiting groove (41); the limiting groove (41) gradually converges from the port inwards until the groove width of the limiting groove (41) is consistent with the outer diameter of the hose (3).

2. The intravenous self-administration cannula according to claim 1, characterized in that: The gasket (4) comprises a supporting portion (42) and a column portion (43) protruding from the supporting portion (42); the bottom of the connecting head (2) is accommodated on the column portion (43); the limiting groove (41) is arranged on the supporting portion (42) so that the horizontal portion (11) is arranged in the supporting portion (42).

3. The intravenous self-administration cannula according to claim 1, characterized in that: The inner diameter of the hose (3) is compatible with the outer diameters of the vertical portion (12) and the horizontal portion (11) of the conduit (1), and the connecting section of the conduit (1) is sealed and connected to the conduit (1).

4. The intravenous self-administration cannula according to claim 3, characterized in that: The connector (2) is sleeved on the outside of the middle part of the vertical part (12), the end of the connecting end (a) of the conduit (1) is arranged in the connector (2), and the conduit (1) is sealed and connected to the vertical part (12).

5. The intravenous self-administration cannula according to claim 1, characterized in that: The end of the insertion end (b) is formed with an oblique cut.

6. The intravenous self-administration cannula according to claim 1, characterized in that: The soft tube (3) is provided with a silica gel ball (5) which can be implanted into a blood vessel.

7. The intravenous self-administration cannula according to claim 1, characterized in that: The contour of the limiting groove (41) is in an arc shape.

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