Intravenous injection auxiliary fixing device for white mouse experiment
By designing an intravenous injection-assisted fixation device for large white rat experiments, the problem of the failure to effectively fix the tail of white rats in the prior art is solved, and the stable fixation of the tail during the injection process is achieved, which improves the accuracy and success rate of the experiment.
Patent Information
- Application Number
- CN202421068588.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-16
- Publication Date
- 2025-03-07
- Estimated Expiration
- 2034-05-16
AI Technical Summary
The existing large white rat fixator cannot effectively fix the tail of the white rat, causing the tail to slide during the tail vein injection, affecting the accuracy and success rate of the experiment.
An intravenous injection assisted fixation device is designed, including a box, groove, slot, elastic band and fixing structure. Through these components, the head, neck, hip and tail of the rat are fixed in specific positions to ensure that the tail remains stable during the injection process.
The device can effectively fix the tail of the rat, ensure the accuracy and success rate of the injection process, and reduce the experimental failure caused by the tail slip.
Smart Images

Figure CN222566019U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of white mouse experiments, in particular to an intravenous injection auxiliary fixing device used for white mouse experiments. Background Art
[0002] Rat is a common experimental animal in medical research, and is also a common animal in experiments in medical physiology, pharmacology, pathology, pathophysiology and other disciplines. Rat tail vein injection is a common injection method in pharmacology, toxicology, genetics, tumors, immunology and other experimental fields; some experiments, such as HBV high-pressure tail vein injection to establish HBV-infected rat models, require that about 1 ml of plasmid solution be quickly and accurately injected into the rat through the tail vein within 10 seconds, while the cell adoptive transfer technology in immunology requires that the adopted immune cells be injected into the rat at a uniform speed and slowly within a few minutes; therefore, the tail of the experimental rat needs to be effectively fixed, which becomes a decisive factor in determining the success or failure of the experiment, which is particularly important. Most of the existing rat fixers use the rat body to fix the rat. This fixation method cannot ensure that the tails of all experimental rats are firmly fixed. During the injection process, the tail is easily caused to slip, resulting in experimental failure.
[0003] In view of the above problems, the present utility model is proposed. Utility Model Content
[0004] In view of the shortcomings of the prior art, the purpose of the utility model is to provide an intravenous injection auxiliary fixation device for rat experiments to solve the problems mentioned in the background technology.
[0005] In order to solve the above technical problems, the utility model provides the following technical solutions.
[0006] The utility model provides an intravenous injection auxiliary fixing device for white mouse experiments, comprising a box body, the top surface of the box body is open, the back of the box body is provided with a first groove penetrating the box body, the front of the box body is provided with a second groove penetrating the box body, the second groove is aligned with the first groove front and back, and the lower surface of the second groove is symmetrically provided with two card slots;
[0007] A support plate is provided extending outward from the lower front side of the box body, the support plate is aligned with the central axis of the second groove in the horizontal direction, and two fixing structures are provided at the front and rear of the support plate;
[0008] The inner wall of the back side of the box body is provided with a plurality of first protrusions on both sides of the first groove, and a first elastic band is connected between the first protrusions on both sides. The inner wall of the front side of the box body is provided with a plurality of second protrusions on both sides of the second groove, and a second elastic band is connected between the second protrusions on both sides.
[0009] Preferably, the fixing structure includes a base plate, a pressure plate, a screw, a handle, a first baffle and a second baffle, the base plate is arranged on the upper surface of the support plate, the pressure plate is located directly above the base plate, the handle is fixed to the upper end of the screw, the lower end of the screw passes through the pressure plate and is threadedly connected to the base plate, the first baffle is arranged on the screw and is located above the pressure plate, and the second baffle is arranged on the screw and is located below the pressure plate.
[0010] Preferably, the screw is plugged into the pressing plate, the lower surface of the first baffle is in contact with the upper surface of the pressing plate, and the upper surface of the second baffle is in contact with the lower surface of the pressing plate.
[0011] Preferably, the middle portion of the pressing plate is in the shape of an upwardly protruding arc, and the curvature of the middle portion of the pressing plate close to the second groove is greater than that of the middle portion of the pressing plate far from the second groove.
[0012] Preferably, the height of the first elastic band in the vertical direction is higher than the inner bottom surface of the first groove, and the height of the second elastic band in the vertical direction is higher than the inner bottom surface of the second groove.
[0013] Preferably, the inner bottom surfaces of the first groove and the second groove are uniformly semicircular.
[0014] Preferably, there are a plurality of the first convex pillars and the second convex pillars, which are distributed in a straight line with equal intervals.
[0015] Compared with the prior art, the utility model has the following beneficial effects:
[0016] The rat is placed in the box body, the head of the rat is located in the first groove, the buttocks of the rat is located in the second groove, the two hind legs of the rat are straightened and respectively located in the card slots, the first elastic band is fixed on the neck of the rat, and the second elastic band is fixed on the buttocks of the rat; in this way, the rat is firmly fixed;
[0017] The tail of the rat is straightened and placed flat on the two base plates. The screw rod moves downward while holding the screw handle. The two screw rods drive the pressing plates to move downward respectively, so that the middle curved part of the pressing plate can press the tail of the rat.
[0018] There are two pressing plates, which can firmly press the entire tail of the rat, so that it is convenient to use a syringe to inject into the rat's tail vein; the first elastic band and the second elastic band can be fixed on the first convex column and the second convex column at different positions, so that the downward pressure of the first elastic band and the second elastic band on the neck and buttocks of the rat can be adjusted. The whole device can be promoted and used in the intravenous injection experiment of the rat. BRIEF DESCRIPTION OF THE DRAWINGS
[0019] Figure 1 It is a three-dimensional diagram of the utility model;
[0020] Figure 2 It is a three-dimensional diagram of the utility model;
[0021] Figure 3 It is a three-dimensional diagram of the utility model.
[0022] In the figure: 1, box body; 11, first groove; 12, second groove; 13, slot; 14, first convex column; 15, first elastic band; 16, second convex column; 17, second elastic band; 2, support plate; 21, seat plate; 3, pressure plate; 31, screw; 32, screw handle; 33, first baffle; 34, second baffle. DETAILED DESCRIPTION
[0023] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.
[0024] In the description of the present invention, it should be understood that the terms "upper", "lower", "front", "back", "left", "right", "top", "bottom", "inside", "outside", etc., indicating directions or positional relationships, are based on the directions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore should not be understood as a limitation on the present invention.
[0025] like Figure 1-3 As shown, an intravenous injection auxiliary fixation device for rat experiments comprises a box body 1, the top surface of the box body 1 is open, a first groove 11 penetrating the box body 1 is arranged on the back of the box body 1, a second groove 12 penetrating the box body 1 is arranged on the front of the box body 1, the second groove 12 is aligned with the first groove 11 front and back, and two clamping grooves 13 are symmetrically arranged on the lower surface of the second groove 12, the two backs of the rat are respectively placed in the clamping grooves 13, the head and neck of the rat are placed in the first groove 11, and the buttocks of the rat are placed in the second groove 12;
[0026] A support plate 2 is provided extending outward from the lower front of the box body 1, and the support plate 2 is aligned with the horizontal central axis of the second groove 12. Two fixing structures are provided on the front and back of the support plate 2, and the tail of the rat is placed on the support plate 2;
[0027] The inner wall of the back side of the box body 1 is provided with a plurality of first protrusions 14 on both sides of the first groove 14, and a first elastic band 15 is connected between the first protrusions 14 on both sides. The inner wall of the front side of the box body 1 is provided with a plurality of second protrusions 16 on both sides of the second groove 12, and a second elastic band 17 is connected between the second protrusions 16 on both sides. The first elastic band 15 presses the head and neck of the rat, and the second elastic band 17 presses the buttocks of the rat.
[0028] The fixing structure includes a base plate 21, a pressure plate 3, a screw 31, a knob 32, a first baffle 33 and a second baffle 34. The base plate 21 is arranged on the upper surface of the support plate 2, the pressure plate 3 is located directly above the base plate 21, the knob 32 is fixed to the upper end of the screw 31, the lower end of the screw 31 passes through the pressure plate 3 and is threadedly connected to the base plate 21, the first baffle 33 is arranged on the screw 31 and is located above the pressure plate 3, and the second baffle 34 is arranged on the screw 31 and is located below the pressure plate 3.
[0029] The screw rod 31 is plugged into the pressing plate 3 , the lower surface of the first baffle plate 33 is in contact with the upper surface of the pressing plate 3 , and the upper surface of the second baffle plate 34 is in contact with the lower surface of the pressing plate 3 .
[0030] The middle portion of the pressing plate 3 is in the shape of an arc that bulges upward, and the curvature of the middle portion of the pressing plate 3 close to the second groove 12 is greater than that of the middle portion of the pressing plate 3 far from the second groove 12 .
[0031] The height of the first elastic band 15 in the vertical direction is higher than the inner bottom surface of the first groove 11, and the height of the second elastic band 17 in the vertical direction is higher than the inner bottom surface of the second groove 12; the inner bottom surfaces of the first groove 11 and the second groove 12 are uniformly semicircular; there are a plurality of first convex columns 14 and second convex columns 16, which are distributed in a straight line with equal spacing.
[0032] In summary: the rat is placed in the box body 1, the rat's head is located in the first groove 11, the rat's buttocks are located in the second groove 12, the rat's two hind legs are straightened and respectively located in the slots 13, the first elastic band 15 is fixed on the rat's neck, and the second elastic band 17 is fixed on the rat's buttocks; in this way, the rat is firmly fixed;
[0033] The tail of the rat is straightened and laid flat on the two base plates 21, and the screw rod 31 moves downward while holding the screw handle 21. The two screw rods 31 drive the pressing plate 3 to move downward respectively, so that the middle curved part of the pressing plate 3 can press the tail of the rat;
[0034] There are two pressing plates 3, which can firmly press the entire tail of the rat, so that it is convenient to use a syringe to inject into the rat's tail vein; the first elastic belt 15 and the second elastic belt 17 can be fixed on the first convex column 14 and the second convex column 16 at different positions, so that the downward pressure of the first elastic belt 15 and the second elastic belt 17 on the neck and buttocks of the rat can be adjusted. The whole device can be promoted and used in the intravenous injection experiment of the rat.
[0035] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes within the technical scope disclosed by the present invention according to the technical scheme and the utility model concept of the present invention, which should be covered by the protection scope of the present invention.
Claims
1. An intravenous injection auxiliary fixation device for rat experiments, characterized in that: The box body (1) comprises a box body (1), the top surface of the box body (1) is open, the back surface of the box body (1) is provided with a first groove (11) penetrating the box body (1), the front surface of the box body (1) is provided with a second groove (12) penetrating the box body (1), the second groove (12) is aligned with the first groove (11) in front and back, and the lower surface of the second groove (12) is symmetrically provided with two card slots (13); A support plate (2) is provided extending outward from the lower front side of the box body (1), the support plate (2) is aligned with the central axis of the second groove (12) in the horizontal direction, and two fixing structures are provided on the front and rear of the support plate (2); The inner wall of the back side of the box body (1) is provided with a plurality of first convex columns (14) on both sides of the first groove (14), and a first elastic band (15) is connected between the first convex columns (14) on both sides; the inner wall of the front side of the box body (1) is provided with a plurality of second convex columns (16) on both sides of the second groove (12), and a second elastic band (17) is connected between the second convex columns (16) on both sides.
2. The intravenous injection auxiliary fixation device for rat experiments according to claim 1, characterized in that: The fixing structure comprises a base plate (21), a pressing plate (3), a screw (31), a handle (32), a first baffle (33) and a second baffle (34); the base plate (21) is arranged on the upper surface of the support plate (2); the pressing plate (3) is located directly above the base plate (21); the handle (32) is fixed to the upper end of the screw (31); the lower end of the screw (31) passes through the pressing plate (3) and is threadedly connected to the base plate (21); the first baffle (33) is arranged on the screw (31) and is located above the pressing plate (3); and the second baffle (34) is arranged on the screw (31) and is located below the pressing plate (3).
3. The intravenous injection auxiliary fixation device for rat experiments according to claim 2, characterized in that: The screw rod (31) is plugged into the pressing plate (3), the lower surface of the first baffle plate (33) is in contact with the upper surface of the pressing plate (3), and the upper surface of the second baffle plate (34) is in contact with the lower surface of the pressing plate (3).
4. The intravenous injection auxiliary fixation device for rat experiments according to claim 2, characterized in that: The middle part of the pressing plate (3) is in the shape of an arc that bulges upward, and the curvature of the middle part of the pressing plate (3) close to the second groove (12) is greater than that of the middle part of the pressing plate (3) far from the second groove (12).
5. The intravenous injection auxiliary fixation device for rat experiments according to claim 1, characterized in that: The height of the first elastic band (15) in the vertical direction is higher than the inner bottom surface of the first groove (11), and the height of the second elastic band (17) in the vertical direction is higher than the inner bottom surface of the second groove (12).
6. The intravenous injection auxiliary fixation device for rat experiments according to claim 1, characterized in that: The inner bottom surfaces of the first groove (11) and the second groove (12) are uniformly semicircular.
7. The intravenous injection auxiliary fixation device for rat experiments according to claim 1, characterized in that: There are a plurality of first convex columns (14) and second convex columns (16), which are distributed in a straight line at equal intervals.