Atomization catheter and atomization equipment

Abstract

The embodiment of the utility model discloses an atomization guide pipe and atomization equipment. The atomization catheter comprises a catheter body and an atomization head arranged at the far end of the catheter body. The atomization head comprises an atomization chip and a nozzle, wherein the atomization chip is communicated with the tube body; the atomization chip comprises a first unit piece and a second unit piece which are stacked, and at least one group of micro-channels are etched on one side surface, attached to the second unit piece, of the first unit piece; the chip support is provided with a through area penetrating through the axial direction of the chip support, the atomization chip is installed in the through area in a sealed mode, and the chip support is connected with the far end of the pipe body. The atomization guide pipe is simple in structure, the rejection rate of the atomization chip is low, the machining difficulty and cost are greatly reduced, and the atomization guide pipe is suitable for smaller cavities.

Description

Technical Field

[0001] The present application relates to the field of medical devices, and in particular to an atomization catheter and an atomization device. Background Art

[0002] Nebulizer therapy can be used clinically to achieve inhalation therapy and ablation therapy. Inhalation therapy generally uses a nebulizer to disperse the drug into tiny droplets or particles through a nebulizer catheter, suspending the drug in the gas and allowing it to enter natural cavities such as the respiratory tract and lungs to treat the lesions.

[0003] However, the internal structure of the current atomizer catheter is relatively complex, which results in a relatively large size of the atomizer catheter, making it unsuitable for use in the tiny natural cavities of the human body and increasing the difficulty and cost of processing. Utility Model Content

[0004] The embodiments of the present application provide an atomization catheter and an atomization device with a simplified internal structure and reduced processing difficulty, thereby solving the technical problems that the existing atomization catheter cannot be applied to small natural cavities and has high processing difficulty and cost.

[0005] The embodiment of the present application provides an atomizing catheter, the atomizing catheter comprises a tube body and an atomizing head arranged at the distal end of the tube body; the atomizing head comprises: an atomizing chip, which is connected to the tube body, the atomizing chip comprises a first unit sheet and a second unit sheet stacked, and at least one group of microchannels are etched on a side surface where the first unit sheet and the second unit sheet are bonded; a chip bracket, which is provided with a through-area that runs through the axial direction of the chip bracket, the atomizing chip is sealed and installed in the through-area, and the chip bracket is connected to the distal end of the tube body. By etching at least one group of microchannels only on one side surface of the first unit sheet, the problem that the two sides of the first unit sheet are difficult to align when the microchannels are etched on both sides of the first unit sheet, resulting in increased cutting difficulty and higher scrap rate, is solved without affecting the original flow of the atomizing catheter. Further, the sealed and stable installation of the atomizing chip can be realized through the chip bracket, and the components used to install the chip inside the atomizing catheter are reduced, thereby simplifying the structure of the atomizing catheter, which is conducive to reducing the outer diameter of the atomizing catheter to be suitable for a smaller cavity, and reducing the processing cost.

[0006] In a feasible solution, the chip holder is also provided with a hollow area running through its circumference, and a glue dispensing gap is formed between the inner side wall of the hollow area and the chip holder. By setting the glue dispensing gap, the glue dispensing is made more uniform and the glue dispensing difficulty is reduced, thereby ensuring that the chip is stably installed in the chip holder and has good sealing performance with the chip holder.

[0007] In a feasible solution, the atomizer head also includes a connecting sleeve, which is a hollow cylindrical structure. The connecting sleeve is arranged in the chip holder and is located at the proximal end of the atomizer chip. A buffer gap is set between the connecting sleeve and the atomizer chip; the tube body includes an inner tube and an outer tube that are nested with each other, the inner tube passes through the connecting sleeve and is connected to the fluid inlet of the atomizer chip, and the distal end of the outer tube abuts against and is connected to the connecting sleeve and the proximal end of the chip holder.

[0008] In a feasible solution, the atomization chip further includes a fluid inlet section and a fluid outlet arranged opposite to each other in the longitudinal direction thereof, each group of the microchannels is equipped with a fluid outlet, a fluid inlet is provided through the fluid inlet section, and multiple groups of the microchannels are connected to the fluid inlet section to share a fluid inlet. Multiple groups of the microchannels share a fluid inlet, which is conducive to simplifying the structure of the chip and reducing processing costs.

[0009] In a feasible solution, the atomization chip includes a first flow divider and a second flow divider extending along the fluid flow direction, and the first flow divider and the second flow divider are arranged in pairs in the fluid inlet section. The first flow divider and the second flow divider are used to divide the fluid flowing into the fluid inlet, so that the fluid is evenly divided into each group of microchannels for atomization, thereby avoiding excessive concentration of the fluid and optimizing the atomization effect.

[0010] In a feasible solution, the length of the first flow diverter is greater than the length of the second flow diverter. With this arrangement, after the first flow diversion is performed by the first flow diverter, the second flow diverter is continued to perform the second flow diverter, which optimizes the flow diversion effect and can reduce the chip space occupied by the second flow diverter while ensuring the flow diversion effect.

[0011] In a feasible solution, every two of the first flow dividers and / or the second flow dividers located on both sides of the center line of the atomizer chip are arranged relatively tilted in an eight-shaped shape, and gradually expand and tilt along the fluid inlet toward the inside of the atomizer chip.

[0012] In a feasible solution, two groups of microchannels are etched on the first unit chip, and the two groups of microchannels are arranged in parallel along the transverse direction of the chip. By etching two groups of microchannels, the atomization flow rate can be increased without affecting the atomization effect.

[0013] In a feasible solution, each group of the microchannels includes a flow diversion section, a pressurization section, and an atomization section sequentially distributed along the fluid flow direction; one or more groups of pressurization channels are arranged in parallel in the pressurization section.

[0014] Each guide column in each group of the boost flow channel is arranged obliquely along the extension direction of the boost flow channel. Each boost flow channel has a tendency to gradually narrow, and the narrowed boost flow channel gradually increases the fluid pressure from the fluid inlet to the fluid outlet, thereby increasing the fluid flow rate and optimizing the atomization effect; the obliquely arranged guide column guides the flow of the fluid, which is conducive to improving the atomization effect of the atomization chip.

[0015] In a feasible solution, each of the guide columns in each group of the boost flow channels is inclined from the outer side of the boost flow channels along the inner side toward the fluid outlet at the far end of the atomization chip; and / or, each of the guide columns in each group of the boost flow channels is inclined from the outer side of the boost flow channels along the inner side toward the fluid inlet at the proximal end of the atomization chip. It can be understood that the guide column is inclined from the outer side of the boost flow channel along the inner side toward the fluid outlet at the far end of the atomization chip, then along the axial direction of the boost flow channel, the flow resistance of the guide column to the fluid is reduced, thereby reducing the pressure loss of the fluid, which is beneficial to improving the atomization efficiency; and if the guide column is inclined from the outer side of the boost flow channel along the inner side toward the fluid inlet at the proximal end of the atomization chip, then in the direction along the axial direction of the boost flow channel, the fluid impacts on the side of the guide column close to the inner side of the boost flow channel, so that the dispersed fluid and the fluid newly flowing into the chip impact and mix in advance, thereby optimizing the atomization effect, and when the fluid flows from the inner side of the boost flow channel to the outer side for filtration, the guide column is inclined toward the fluid inlet side, thereby reducing the resistance to the fluid and improving the filtration efficiency.

[0016] In a feasible solution, the inner side walls of each group of the microchannels gradually converge at a position adjacent to the fluid outlet; the atomization chip further includes a flow guide, which is arranged in each group of the microchannels and adjacent to the outlet, and the flow guide separates the position adjacent to the fluid outlet into two branches, and the two branches bypass the flow guide and meet at the fluid outlet. The flow guide and the two side walls of the corresponding microchannel form two narrower channels, i.e., two branches, and the liquid is squeezed out through the narrow branches, and the liquid is squeezed out along the tangent direction of the cylinder, and the liquids on both sides of the channels collide to form more uniform and smaller aerosol droplets, which enter the human body.

[0017] An embodiment of the present application also provides an atomization device, which includes a pressurizing device and an atomization conduit, and the atomization conduit is the atomization conduit described in any of the above embodiments; wherein the pressurizing device includes a pressurizing component and a driving component, the pressurizing component is connected to the atomization conduit and pressurizes the atomization conduit, and the driving component is connected to the pressurizing component for driving the pressurizing component to generate pressure.

[0018] Based on the above scheme, it can be known that the present application solves the problem that when etching microchannels on both sides of the first unit chip, the two sides of the first unit chip are difficult to align when cutting, resulting in increased cutting difficulty and high scrap rate, by etching at least one group of microchannels only on one side surface of the first unit chip, without affecting the original flow rate of the atomization duct. Furthermore, the chip bracket can be used to achieve sealed and stable installation of the atomization chip, reduce the components inside the atomization duct for installing the chip, thereby simplifying the structure of the atomization duct, which is conducive to reducing the outer diameter of the atomization duct to adapt to smaller cavities and reducing processing costs. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, a brief introduction will be given below to the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative labor.

[0020] Figure 1 The overall structure of the atomization conduit in one embodiment of the present application is schematically shown;

[0021] Figure 2 An exploded view of an atomizer head in one embodiment of the present application;

[0022] Figure 3 for Figure 2 A cross-sectional view of the atomizer head in FIG.

[0023] Figure 4 A top view of an atomization chip in one embodiment of the present application;

[0024] Figure 5 for Figure 4 A local enlarged view of point A in FIG.

[0025] Figure 6 for Figure 5 A local enlarged view of point B in FIG.

[0026] Figure 7 for Figure 4 A side view of the atomizer chip in FIG.

[0027] Figure 8 It is a top view of an atomization chip in one embodiment of the present application.

[0028] Numbers in the figure:

[0029] 100, tube body; 110, outer tube; 120, inner tube; 130, limiting sleeve;

[0030] 200, pipe joint;

[0031] 300, atomizer head; 310, connecting sleeve; 320, atomizer chip; 3201, first unit chip; 3202, second unit chip; 321, fluid inlet; 322, diverter; 3221, first diverter; 3222, second diverter; 323, first spacer; 324, pressurization channel; 325, second spacer; 326, distribution member; 327, guide member; 328, fluid outlet; 329, guide column; 330, chip bracket; 331, hollow area; 332, through area; 333, buffer gap; H1, diverter section; H2, pressurization section; H3, atomizer section. DETAILED DESCRIPTION

[0032] In order to make the purpose, technical solution and advantages of the embodiments of the present application clearer, the technical solution in the embodiments of the present application will be clearly and completely described below in conjunction with the drawings in the embodiments of the present application. Obviously, the described embodiments are part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0033] In the description of the present application, it should be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present application.

[0034] In this application, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integrated connection; it can be a mechanical connection, an electrical connection, or a communication connection; it can be a direct connection, or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances. The technical solution of the present application is described in detail with specific embodiments below. The following specific embodiments can be combined with each other, and the same or similar concepts or processes may not be repeated in some embodiments.

[0035] Usually, atomization therapy is used to treat diseases of the human bronchi and lungs. The existing oral or nasal atomization drug delivery method, due to the long airway of the human body, it is difficult for the atomized particles to reach the distal end of the lungs, and most of them are deposited in the mouth, nose and main bronchi, which cannot deliver the drug accurately; in addition, due to the size of the device, it is impossible to deliver the drug deep into the airway, and the treatment effect is poor, which needs to be improved.

[0036] However, the existing atomization catheters suitable for inserting into the natural cavities of the human body have relatively complex internal structures, which leads to relatively large sizes of the atomization catheters, making them inapplicable to the tiny natural cavities of the human body, and increasing the difficulty and cost of processing.

[0037] In one embodiment of the present application, Figure 1 As shown, the atomizing catheter of this embodiment includes a tube body 100 and an atomizing head 300 disposed at the distal end of the tube body 100. One end of the tube body 100 is a proximal end, and the other end is a distal end that can extend into the bronchus. The interior of the tube body 100 is provided with a channel that can transport fluid from the proximal end to the distal end. The proximal end of the tube body 100 is connected to an external fluid transport device, and the distal end of the tube body 100 is connected to the atomizing head 300. The fluid in the channel of the tube body 100 is atomized and then output through the atomizing head 300.

[0038] The tube body 100 of the atomizing catheter of this embodiment has certain flexibility and a small outer diameter, and can enter the deep lungs for precise drug delivery. This embodiment has no strict restrictions on the outer diameter, length and other size parameters of the tube body 100, but it can at least extend into the bronchus and reach the lesion site.

[0039] The tube body 100 can be in the form of a single tube or multiple tubes according to the needs of conveying fluid. When multiple tubes are used, at least two tubes can be arranged side by side or nested inside and outside. Each tube can be configured independently or use an integrated multi-lumen tube.

[0040] like Figure 1 As shown, the tube body 100 includes an inner tube 120 and an outer tube 110 which are nested with each other, wherein the lumen of the inner tube 120 serves as a channel for conveying fluid, the distal end of the inner tube 120 is connected to the atomizing head 300 for conveying fluid, and the outer tube 110 serves as a supporting and protective component.

[0041] like Figure 1 As shown, the atomization catheter includes a pipe joint 200, which is used to be connected to a perfusion device or a storage device for conveying fluid. The pipe joint 200 can be fixedly assembled at the proximal end of the outer tube 110 and communicated with the inner tube 120. The distal end of the inner tube 120 is communicated with the atomization head 300. The fluid is input into the inner tube 120 through the pipe joint 200 and conveyed to the distal end until it is atomized at the atomization head 300 and then administered to the lesion.

[0042] The pipe connector 200 (such as a Luer connector) and the tube body 100 may be connected by bonding, interference fit, welding, threaded connection or snap connection. In one embodiment, the pipe connector 200 and the outer tube 110 are fixed by bonding (such as by UV glue curing connection).

[0043] like Figure 3 As shown, the atomizing catheter further includes a limiting sleeve 130 , which is sleeved outside the inner tube 120 and located between the inner tube 120 and the outer tube 110 , and is used to fill the gap between the inner tube 120 and the outer tube 110 , thereby limiting the shaking of the inner tube 120 .

[0044] Optional, such as Figure 3 As shown, the length of the inner tube 120 is less than that of the outer tube 110, and the inner tube 120 and the outer tube 110 are sealed and fixed by a limiting sleeve 130. After the fluid flows into the pipe joint 200, it is transported to the inner tube 120 through the outer tube 110 and then transported to the atomization chip 320 for atomization. Such an arrangement greatly shortens the length of the inner tube 120, reduces the weight of the atomization conduit, and reduces the material cost.

[0045] In order to facilitate passage through the thinner bronchus, the outer diameter of the tube body 100 is generally not greater than 1.2mm to 2.0mm. For example, the outer diameter of the atomizing catheter is 1.8mm, which can reach the lung segment that the endoscope cannot reach to achieve precise atomization drug delivery. Of course, the outer diameter of the atomizing catheter also needs to take into account the width of the atomizing chip 320. In other embodiments, due to the improvement of the structure of the atomizing chip 320 itself, the outer diameter of the atomizing catheter can be designed to be smaller, such as 1.3mm, 1.6mm, etc.

[0046] Since the atomizing catheter of the present application can extend into the bronchus, its length is also matched accordingly, for example, the length of the tube body 100 is 800 mm to 1200 mm. In other embodiments, a shorter or longer length can be designed according to the applicable purpose of the atomizing catheter.

[0047] like Figure 2 and Figure 3 As shown, the atomizer head 300 includes an atomizer chip 320 and a chip holder 330. The atomizer chip 320 is in communication with the tube body 100 and is used to atomize the fluid transported in the tube body 100. The chip holder 330 is connected to the distal end of the tube body 100, and a through-area 332 that runs through the axial direction of the chip holder 330 is provided. The atomizer chip 320 is sealed and installed in the through-area 332 to achieve a stable installation of the atomizer chip 320. With such an arrangement, the number of components for installing the chip inside the atomizer conduit is small and the structure is simple, thereby simplifying the structure of the atomizer conduit, which is conducive to reducing the outer diameter of the atomizer conduit to be suitable for a smaller cavity and reducing the processing cost.

[0048] like Figure 2 and Figure 3 As shown, the atomizer chip 320 with a relatively small volume is usually installed by bonding. In this embodiment, a hollow area 331 is also provided on the chip holder 330, which runs through the circumference of the chip holder 330. A glue dispensing gap is formed between the inner side wall of the hollow area 331 and the chip holder 330. By setting the glue dispensing gap, a certain operating space is provided, so that the glue dispensing is more uniform and the glue dispensing difficulty is reduced. The glue-like substance can also fully fill the space between the chip holder 330 and the atomizer chip 320, so as to ensure that the chip is stably installed in the chip holder 330 and has good sealing performance with the chip holder 330. In addition, the hollow area 331 can further reduce weight and improve the compliance of the atomizer catheter.

[0049] like Figure 2 and Figure 3 As shown, the atomizer head 300 also includes a connecting sleeve 310, which is arranged in the chip holder 330 and is located at the proximal end of the atomizer chip 320; the inner tube 120 of the tube body 100 passes through the connecting sleeve 310 and is connected to the fluid inlet 321 of the atomizer chip 320; the distal end of the outer tube 110 is abutted and connected to the connecting sleeve 310 and the proximal end of the chip holder 330. The two ends of the atomizer chip 320 are limited by the chip holder 330 and the connecting sleeve 310 to prevent the chip from shifting or even falling off. The inner tube 120 extends into the connecting sleeve 310 and is connected to the fluid inlet 321 of the atomizer chip 320. The connecting sleeve 310 limits the inner tube 120 to prevent the inner tube 120 from shaking. Further, the inner tube 120 can be fixedly connected to the connecting sleeve 310 by welding or bonding to improve the stability of the installation.

[0050] Optionally, in one embodiment, the connection sleeve 310 is a hollow cylindrical structure, and the corresponding through-area 332 of the chip holder 330 is formed in a cube, and the outer diameter of the connection sleeve 310 is adapted to the width of the through-area 332, so that during installation, the outer wall of the connection sleeve 310 and the inner wall of the through-area 332 are interference-fitted to achieve rapid assembly, and the installation method is simple. In other embodiments, the method of matching and installing between the connection sleeve 310 and the chip holder 330 is not limited to the above, for example, the installation and fixation can also be achieved by bonding or welding.

[0051] Optionally, a buffer gap 333 is set between the connecting sleeve 310 and the atomization chip 320. The buffer gap 333 provides a certain state adjustment space for the fluid before entering the atomization chip 320. After the fluid enters the atomization chip 320, it has a better dispersion effect, making the fluid dispersion more uniform.

[0052] like Figures 4 to 7As shown, the atomization chip 320 includes a first unit sheet 3201 and a second unit sheet 3202 stacked together, at least one group of microchannels are etched on one side surface of the first unit sheet 3201, and the etched side surface is fitted with the second unit sheet 3202. In this way, the problem that the two side surfaces of the first unit sheet 3201 are difficult to align when cutting when etching microchannels on both sides of the first unit sheet 3201, resulting in increased cutting difficulty and a high scrap rate, can be solved without affecting the flow rate of the atomization duct.

[0053] In one embodiment, the first unit chip 3201 is set as a silicon chip, and the second unit chip 3202 is set as a silica glass chip. The silicon chip and the glass chip are assembled and bonded. The fluid is continuously transmitted and divided in the microchannel between the silicon chip and the glass chip and collides with each other to disperse and atomize. The median particle size of the atomized fluid particles is usually 20 microns, and the atomized particle size range is 5-30 microns.

[0054] like Figure 4 As shown, the atomization chip 320 also includes a fluid inlet section and a fluid outlet 328 arranged relatively along its longitudinal direction, and each group of microchannels is equipped with a fluid outlet 328 (i.e., a spray port); a fluid inlet 321 is arranged through the fluid inlet section, and multiple groups of microchannels are connected to the fluid inlet section to share a fluid inlet 321, which is conducive to simplifying the structure of the chip and reducing processing costs.

[0055] like Figure 4 and Figure 5 As shown, in this embodiment, two groups of microchannels are arranged in parallel along the transverse direction of the atomization chip 320. After the fluid is diverted from the fluid inlet section, it enters the two groups of microchannels respectively for continuous diversion and atomization, and then outputs through the respective matching fluid outlets 328. Two groups of microchannels are set up, and the output of the atomization conduit is increased without increasing the overall width of the atomization chip 320, saving costs and not affecting the atomization effect. Of course, in other embodiments, the number of groups of microchannels is not limited to the above, for example, one group, three groups, four groups, etc. can be set, depending on the outer diameter of the atomization conduit and the required atomization flow rate.

[0056] Specifically, in another embodiment, Figure 8 As shown, a group of microchannels are etched on the first unit chip 3201. Figure 4 The atomizer chip 320 shown has two sets of microchannels etched thereon. The width of the atomizer chip 320 in this embodiment can be set to be narrower, and the outer diameter of the atomizer catheter is correspondingly reduced. In this way, the atomizer catheter can be inserted into a smaller cavity, which is suitable for the treatment of pediatric lung diseases and smaller bronchial diseases.

[0057] like Figure 4As shown, the atomization chip 320 includes a diverter extending along the fluid flow direction, and the diverter is used to divert the fluid flowing into the fluid inlet 321 so that the fluid is evenly diverted to each group of microchannels for atomization, thereby avoiding excessive concentration of the fluid and optimizing the atomization effect.

[0058] like Figure 4 As shown, the flow divider includes a first flow divider 3221 and a second flow divider 3222. The first flow divider 3221 and the second flow divider 3222 are arranged in pairs in the fluid inlet section to guide and divide the fluid.

[0059] like Figure 4 As shown, the length of the first diverter 3221 is greater than the length of the second diverter 3222. With this arrangement, the fluid is initially diverted through the first diverter 3221 and then continues to be diverted through the second diverter 3222 for a second time, thereby optimizing the diversion effect and reducing the chip space occupied by the second diverter 3222 while ensuring the diversion effect.

[0060] Optionally, every two corresponding first flow diverters 3221 located on both sides of the center line of the atomizer chip 320 and / or every two corresponding second flow diverters 3222 located on both sides of the center line of the atomizer chip 320 are relatively inclined in an eight-shaped arrangement, and gradually expand and incline along the fluid inlet 321 toward the inner direction of the atomizer chip 320. In this way, the flow direction of the fluid can be changed, and the fluid can be evenly distributed at various positions of the microchannel inlet, optimizing the diversion effect, while preventing the fluid from directly impacting the microchannel. The arrangement of the flow diverter can also provide support when the first unit sheet 3201 and the second unit sheet 3202 are assembled.

[0061] like Figure 4 As shown, each group of microchannels includes a flow dividing section H1, a pressurizing section H2, and an atomizing section H3 which are sequentially distributed along the fluid flow direction.

[0062] Among them, Figure 4 As shown, the flow dividing section H1 is used to divide the fluid, and the first flow dividing member 3221 and the second flow dividing member 3222 are located in the flow dividing section H1. The first flow dividing member 3221 divides the fluid inlet section into a plurality of areas.

[0063] like Figure 4 As shown, one or multiple groups of boosting channels 324 are arranged in parallel in the boosting section H2, each of the boosting channels 324 is surrounded by a plurality of guide columns 329 arranged in sequence, and each of the boosting channels 324 has a tendency to gradually narrow, that is, each group of boosting channels 324 narrows in a V-shape along the fluid inlet 321 toward the fluid outlet 328, and the opening of the V-shape faces the fluid inlet 321, so that after the fluid passes through each boosting channel 324, the fluid flow rate and pressure are effectively improved through the continuous narrowing of the boosting channel 324.

[0064] Regarding the narrowing trend of the boosting channel 324 , for example, the vertex angle of the end (ie, the output side) of the boosting channel 324 is 3 to 15 degrees.

[0065] Optionally, each guide column 329 in each group of boosting flow channels 324 is arranged obliquely along the extension direction of the boosting flow channels 324 . The obliquely arranged guide columns 329 guide the flow of the fluid, which is beneficial to improving the atomization effect of the atomization chip 320 .

[0066] In one embodiment, if Figure 6 As shown, each guide column 329 in each group of boost flow channels 324 is inclined from the outer side of the corresponding boost flow channel 324 along the inner side toward the fluid outlet at the far end of the atomization chip 320; in the axial direction of the boost flow channel 324, the inclined guide column 329 guides the flow of the fluid, reduces flow resistance and pressure loss, and thus enables the atomization chip to have a higher atomization efficiency.

[0067] In other embodiments, the inclination direction of the guide column 329 in each group of boost flow channels 324 is not limited to the above. For example, each guide column 329 in each group of boost flow channels 324 may be inclined from the outer side of the boost flow channel 324 along the inner side toward the fluid inlet 321 near the atomization chip 320. In this way, in the axial direction along the boost flow channel 324, the fluid impacts on the side of the guide column 329 close to the inner side of the boost flow channel 324, so that the dispersed fluid and the fluid newly flowing into the atomization chip 320 impact and mix in advance, thereby optimizing the atomization effect. Moreover, when the fluid flows from between two adjacent guide columns 329 along the inner side of the boost flow channel 324 to the outer side for filtration, the guide column 329 is inclined toward the fluid inlet 321 to reduce the resistance to the fluid and improve the filtration efficiency.

[0068] In other embodiments, the inclination directions of the guide posts 329 in each group of pressurized flow channels 324 may be consistent or inconsistent. For example, some guide posts 329 may be inclined toward the fluid inlet 321, while some guide posts 329 may be inclined toward the fluid outlet 328, and the inclination angles may be consistent or inconsistent.

[0069] Furthermore, a first spacer 323 is further provided in the flow splitting section H1, and the first spacer 323 is provided at the entrance of each boosting channel 324, so as to effectively guide the fluid into multiple streams and enter the boosting section H2. It can be understood that the first spacer 323 divides the boosting section H2 into M boosting channels 324, and the first flow splitter 3221 divides the flow splitting section H1 into N regions, where M is greater than N, for example, M=N+(2-8), and for example, M=2N, etc., which is not limited here.

[0070] Optional, such as Figure 6As shown, a second spacer 325 is disposed at the end of each boosting channel 324 to promote the fluid to be discharged from both sides of the boosting channel 324 and further output to the atomization section H3, thereby improving the dispersed atomization effect.

[0071] It can be understood that the first spacer 323 and the second spacer 325 not only play the role of diversion, but also connect and support the first unit sheet 3201 and the second unit sheet 3202 during assembly, increase the connection points and support points, so that the first unit sheet 3201 and the second unit sheet 3202 are evenly stressed and fit firmly.

[0072] In one embodiment, the first spacer 323 and the second spacer 325 are staggered, which is beneficial to optimize the flow diversion effect.

[0073] like Figure 4 and Figure 5 As shown, a plurality of distribution elements 326 are arranged in the atomization section H3. The fluid moves irregularly and expands mutually when flowing through the plurality of distribution elements 326, and is further dispersed into droplets with smaller diameters until it is atomized and sprayed out.

[0074] In one embodiment, the distribution member 326 is columnar or granular, for example, cylindrical, and can be distributed in an array or randomly. The gap between the distribution members 326 should be determined according to the substance to be sprayed, such as fluid viscosity, dispersion of the therapeutic substance or particle size. For example, the gap between the distribution members 326 is generally 5 microns to 100 microns; and the size of the distribution member 326 itself is 10 microns to 20 microns. Taking a cylinder as an example, its height and diameter are both between 10 microns and 20 microns.

[0075] In one embodiment, the distribution member 326 is further arranged near the end of each pressurized flow channel 324 to further split and atomize the fluid split from both sides of the end of the pressurized flow channel 324 to enhance the split atomization.

[0076] As for each group of microchannels as a whole, the reasonable distribution of each section can ensure the atomization effect. For example, the length ratio of the diversion section H1, the boosting section H2 and the atomization section H3 is 1: (2-10): (1-5).

[0077] At the fluid outlet 328 of each group of microchannels of the atomization chip 320, in order to guide the atomization spray direction and further improve the atomization effect, in one embodiment, as Figure 4 and Figure 6As shown, the inner side walls of each group of microchannels gradually converge at a position adjacent to the fluid outlet 328. The atomizer chip 320 also includes a guide 327, which is arranged in each group of microchannels and adjacent to the fluid outlet 328. The guide 327 separates the position adjacent to the fluid outlet 328 into two narrow branches, and the two branches bypass the guide 327 and meet at the fluid outlet 328. The liquid is squeezed out through the narrow branches, and the liquid is squeezed out along the tangent direction of the cylinder. The liquids on both sides of the channels collide to form more uniform and smaller aerosol droplets, which enter the human body.

[0078] In one embodiment, the guide member 327 may be in a strip shape and extend along the flow-guiding direction; or the guide member 327 may be in a columnar structure, and its cross section may be circular, elliptical, or teardrop-shaped, etc. The guide member 327 may be in a columnar shape to avoid dead angles, especially the outer periphery of the columnar structure may have an arc surface structure, which may guide the flow of the fluid and reduce resistance.

[0079] In terms of application, the atomization chip 320 in this embodiment is suitable for fluids such as liquids or gases, such as soluble solutions (without suspended matter), such as injectable medicines, such as medicines for fungal infections, chemotherapy drugs for lung cancer, anesthetics, local tissue stains, etc.

[0080] One embodiment of the present application also provides an atomization device, the atomization device includes a pressurizing device (not shown) and an atomization conduit, the atomization conduit is the atomization conduit described in any of the above embodiments; wherein the pressurizing device includes a pressurizing component and a driving component; the pressurizing component is connected to the atomization conduit and pressurizes the atomization conduit, and the driving component is connected to the pressurizing component to drive the pressurizing component to generate pressure. The atomization conduit is pressurized by the pressurizing component, and a certain pressure is applied to the fluid in the atomization conduit, thereby pushing the fluid into the atomization chip to move rapidly along the microchannel to disperse and impact each other for atomization. In the present application, unless otherwise clearly specified and limited, the first feature "above" or "below" the second feature can be the first feature and the second feature directly contact, or the first feature and the second feature are indirectly contacted through an intermediate medium.

[0081] Moreover, the first feature being “above”, “above”, and “above” the second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. The first feature being “below”, “below”, and “below” the second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0082] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example" or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present application. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, without contradiction.

[0083] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application, rather than to limit it. Although the present application has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present application.

Claims

1. An atomizing catheter, characterized in that: The atomizing catheter comprises a tube body and an atomizing head arranged at the distal end of the tube body; the atomizing head comprises: an atomization chip, connected to the tube body, the atomization chip comprising a first unit sheet and a second unit sheet stacked together, at least one group of microchannels being etched on a side surface where the first unit sheet and the second unit sheet are bonded; The chip support is provided with a through area which penetrates the chip support axially, the atomization chip is sealed and installed in the through area, and the chip support is connected to the far end of the tube body.

2. The atomizing catheter according to claim 1, characterized in that: The chip support is also provided with a hollow area running through the circumference thereof, and a glue dispensing gap is formed between the inner side wall of the hollow area and the chip support.

3. The atomizing catheter according to claim 1, characterized in that: The atomizer head further comprises a connecting sleeve, which is in a hollow cylindrical structure, and is arranged in the chip bracket and located at the proximal end of the atomizer chip, and a buffer gap is arranged between the connecting sleeve and the atomizer chip; The tube body comprises an inner tube and an outer tube which are nested with each other. The inner tube passes through the connecting sleeve and is connected to the fluid inlet of the atomization chip. The distal end of the outer tube abuts against and is connected to the connecting sleeve and the proximal end of the chip bracket.

4. The atomizing catheter according to claim 1, characterized in that: The atomization chip also includes a fluid inlet section and a fluid outlet arranged opposite to each other in its longitudinal direction. Each group of the microchannels is equipped with one fluid outlet. A fluid inlet is provided through the fluid inlet section. Multiple groups of the microchannels are connected to the fluid inlet section to share one fluid inlet.

5. The atomizing catheter according to claim 4, characterized in that: The atomization chip comprises a first flow divider and a second flow divider extending along the fluid flow direction, and the first flow divider and the second flow divider are arranged in pairs in the fluid inlet section.

6. The atomizing catheter according to claim 5, characterized in that: The length of the first flow divider is greater than the length of the second flow divider; Every two of the first flow dividers and / or the second flow dividers located on both sides of the center line of the atomizer chip are arranged relatively tilted in an eight-shaped shape, and gradually expand and tilt along the fluid inlet toward the inside of the atomizer chip.

7. The atomizing catheter according to claim 1, characterized in that: Two groups of microchannels are etched on the first unit chip, and the two groups of microchannels are arranged in parallel along the transverse direction of the chip.

8. The atomizing catheter according to any one of claims 1 to 7, characterized in that: Each group of microchannels comprises a flow dividing section, a pressurizing section, and an atomizing section which are sequentially distributed along the flow direction of the fluid; A group or multiple groups of boosting flow channels are arranged in parallel in the boosting section, each of which is surrounded by a plurality of guide columns arranged in sequence, and each of which has a tendency to gradually narrow; The guide columns in each group of the boosting flow channels are arranged obliquely along the extending direction of the boosting flow channels.

9. The atomizing catheter according to claim 8, characterized in that: Each of the guide columns in each group of the boosting flow channels is inclined from the outer side of the boosting flow channel along the inner side toward the fluid outlet at the far end of the atomization chip; And / or, each of the guide columns in each group of the boosting flow channels is inclined from the outer side of the boosting flow channels along the inner side toward the fluid inlet at the proximal end of the atomization chip.

10. An atomization device, characterized in that: The atomization device comprises a pressurizing device and an atomization conduit, and the atomization conduit is the atomization conduit according to any one of claims 1 to 9; The pressurizing device includes a pressurizing component and a driving component. The pressurizing component is connected to the atomizing conduit and pressurizes the atomizing conduit. The driving component is connected to the pressurizing component and is used to drive the pressurizing component to generate pressure.

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