Chromatin co-immunoprecipitation sample storage device

By designing a chromatin immunoprecipitation sample storage device containing adaptive clamping components, the problem that existing devices are difficult to adapt to sample tubes of different specifications is solved, and the stable storage of sample tubes and the flexibility of the device is achieved.

CN222592168UActive Publication Date: 2025-03-11YUNBAIAO BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202421292266.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-07
Publication Date
2025-03-11
Estimated Expiration
2034-06-07

AI Technical Summary

Technical Problem

Existing chromatin immunoprecipitation sample storage devices are difficult to adapt to sample tubes of different specifications and sizes, resulting in unstable storage.

Method used

A device is designed including a storage box, a positioning plate, a slide chute, a sample storage rack, accommodation slot and a clamping assembly. The clamping assembly can be clamped and positioned according to the diameter of the sample tube through adaptively adjustable give way slots, return springs, sliding posts and clamps.

Benefits of technology

The stable storage of sample tubes of different diameters is achieved, avoiding shaking and pouring, and improving the flexibility and stability of the storage device.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a chromatin co-immunoprecipitation sample storage device which comprises a storage box, positioning plates are fixedly installed on the inner walls of the two sides of the storage box respectively, sliding grooves are formed in the side walls of the opposite sides of the two positioning plates respectively, and a sample storage frame is arranged between the two positioning plates. A plurality of containing grooves are formed in the top of the sample storage rack, sample tubes are arranged in the containing grooves correspondingly, the containing grooves are formed in the sample storage rack, and clamping assemblies are arranged in the containing grooves correspondingly, so that the stored sample tubes can be clamped and positioned; the situation that the sample tubes shake or even topple in the storage process is avoided, the storage stability of the sample tubes is improved, the clamping assemblies can be adjusted in a self-adaptive mode according to the diameters of the sample tubes, the sample tubes with different diameters can be stored, and the use flexibility of the storage device is further improved.
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Description

Technical Field

[0001] The utility model relates to the technical field of chromatin immunoprecipitation, in particular to a chromatin immunoprecipitation sample storage device. Background Art

[0002] In biological science research, chromatin immunoprecipitation technology has become a widely used experimental method for studying the interaction between proteins and DNA in vivo. This technology involves complex experimental steps, from cell fixation, chromatin fragmentation to immunoprecipitation, etc. Each step requires precise control to ensure the accuracy of the experimental results. For the sample storage device used in the chromatin immunoprecipitation experiment, its performance stability and safety are particularly important.

[0003] However, existing storage devices often use sample racks of fixed size or single structure, which makes it difficult for them to adapt to sample tubes of different specifications and sizes. For example, some experiments may require the use of centrifuge tubes of different diameters to store chromatin immunoprecipitation samples, and traditional storage devices cannot be flexibly adjusted to accommodate the storage of these sample tubes of different specifications. Therefore, we need to propose a chromatin immunoprecipitation sample storage device. Summary of the invention

[0004] The utility model aims to provide a chromatin immunoprecipitation sample storage device, aiming to solve the problem that the storage devices in the prior art often adopt sample racks of fixed size or single structure, which makes them difficult to adapt to sample tubes of different specifications and sizes.

[0005] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0006] A chromatin immunoprecipitation sample storage device comprises a storage box, positioning plates are fixedly installed on the inner walls on both sides of the storage box, sliding grooves are respectively opened on the side walls on the opposite sides of two groups of the positioning plates, and a sample storage rack is arranged between the two groups of the positioning plates, a plurality of groups of receiving grooves are opened on the top of the sample storage rack, sample tubes are respectively arranged inside the plurality of groups of the receiving grooves, and clamping components that can be adaptively adjusted and clamp the sample tubes in position are respectively arranged on both sides of the inner walls of the plurality of groups of the receiving grooves.

[0007] Preferably, the clamping assembly includes a clearance groove, which is opened on the inner wall of the accommodating groove, a return spring is fixedly connected to the inner wall of one side of the clearance groove, one end of the return spring is fixedly connected to a sliding column, and one end of the sliding column is fixedly connected to a clamping plate.

[0008] Preferably, the sliding column is slidably inserted into the inside of the clearance groove, and a V-shaped groove is opened on one side wall of the clamping plate.

[0009] Preferably, sliding blocks adapted to the sliding grooves are fixedly connected to the two side walls of the sample storage rack respectively, and the two groups of sliding blocks are respectively slidably connected to the interiors of the two groups of sliding grooves.

[0010] Preferably, guide rods are fixedly connected to the side walls of one sides of the two groups of sliding blocks respectively, one ends of the two groups of guide rods respectively penetrate through the two groups of positioning plates and are fixedly connected with anti-disengagement parts, and the two groups of guide rods are respectively slidably connected to the two groups of positioning plates.

[0011] Preferably, a U-shaped supporting plate is fixedly connected to the bottom of the sample storage rack, and a plurality of groups of supporting pads are fixedly connected to the inner bottom of the U-shaped supporting plate, and the plurality of groups of supporting pads are respectively located directly below the plurality of groups of accommodating grooves.

[0012] Preferably, a refrigeration device body is fixedly installed at the bottom of the storage box, a temperature sensor is fixedly connected to the inner top of the storage box, lighting lamps are fixedly connected to the inner side walls of the two sides of the storage box respectively, and a control panel is fixedly installed on one side wall of the storage box. The refrigeration device body, the temperature sensor and the lighting lamps are all electrically connected to the control panel through wires.

[0013] Compared with the prior art, the beneficial effects of the present utility model are:

[0014] By arranging a plurality of groups of accommodating grooves on the sample storage rack and respectively arranging clamping assemblies inside the plurality of groups of accommodating grooves, the present utility model can clamp and position the stored sample tubes, avoid the situation that the sample tubes shake or even fall down during storage, is beneficial to improving the storage stability of the sample tubes, and the clamping assemblies can be adaptively adjusted according to the diameters of the sample tubes, and can store sample tubes with different diameters, which is beneficial to further improving the use flexibility of the storage device. Description of the Drawings

[0015] Figure 1 is a structural schematic diagram of the present utility model;

[0016] Figure 2 is a structural schematic diagram of the interior of the storage box of the present utility model;

[0017] Figure 3 is a structural schematic diagram of the sample storage rack, the positioning plate and the U-shaped supporting plate of the present utility model;

[0018] Figure 4 is a structural schematic diagram of the sample storage rack and the clamping assembly of the present utility model.

[0019] In the figure: 1, storage box; 2, positioning plate; 3, sliding groove; 4, sample storage rack; 5, receiving groove; 6, sample tube; 7, clamping assembly; 701, relief groove; 702, return spring; 703, sliding column; 704, clamping plate; 8, V-shaped groove; 9, slider; 10, guide rod; 11, C-shaped supporting plate; 12, supporting pad; 13, main body of refrigeration device; 14, temperature sensor; 15, lighting lamp; 16, control panel. Specific implementation mode

[0020] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative work shall fall within the protection scope of the present invention.

[0021] Please refer to Figure 1-4 , the present invention provides a technical solution:

[0022] A chromatin immunoprecipitation sample storage device includes a storage box 1. Positioning plates 2 are respectively fixedly installed on the inner walls on both sides of the storage box 1. Sliding grooves 3 are respectively opened on the opposite side walls of the two groups of positioning plates 2. A sample storage rack 4 is arranged between the two groups of positioning plates 2. A plurality of receiving grooves 5 are opened at the top of the sample storage rack 4. Sample tubes 6 are respectively arranged inside the plurality of receiving grooves 5. Clamping assemblies 7 that can be adaptively adjusted and clamp and position the sample tubes 6 are respectively arranged on both sides of the inner walls of the plurality of receiving grooves 5. By opening a plurality of receiving grooves 5 on the sample storage rack 4 and respectively arranging clamping assemblies 7 inside the plurality of receiving grooves 5, the stored sample tubes 6 can be clamped and positioned, avoiding the situation that the sample tubes 6 shake or even fall during storage, which is beneficial to improving the storage stability of the sample tubes 6. And the clamping assembly 7 can be adaptively adjusted according to the diameter of the sample tube 6, and sample tubes 6 with different diameters can be stored, which is beneficial to further improving the use flexibility of the storage device;

[0023] The clamping assembly 7 includes a relief groove 701 opened on the inner wall of the receiving groove 5. A return spring 702 is fixedly connected to one side inner wall of the relief groove 701. One end of the return spring 702 is fixedly connected to a sliding column 703. One end of the sliding column 703 is fixedly connected to a clamping plate 704;

[0024] Specifically, when the sample tube 6 needs to be stored, the sample tube 6 can be directly inserted into the two sets of clamping plates 704 from top to bottom. The outer wall of the sample tube 6 will squeeze the two sets of clamping plates 704, thereby squeezing the sliding column 703, causing the sliding column 703 to slide into the inside of the让位槽701. At this time, the return spring 702 is in a compressed state. At the same time, the return spring 702 can be used to drive the clamping plate 704 to clamp and position the sample tube 6, avoiding the situation of shaking or even tipping of the sample tube 6 during storage, which is beneficial to improving the stability of the storage of the sample tube 6, and can be adjusted adaptively according to the diameter of the sample tube 6, and sample tubes 6 with different diameters can be stored;

[0025] The sliding column 703 is slidably inserted into the inside of the让位槽701, and a V-shaped groove 8 is provided on one side wall of the clamping plate 704. By setting the V-shaped groove 8, it is beneficial to improve the clamping stability of the cylindrical sample tube 6;

[0026] Sliding blocks 9 adapted to the sliding grooves 3 are respectively fixedly connected to the two side walls of the sample storage rack 4. The two sliding blocks 9 are respectively slidably connected to the inside of the two sliding grooves 3. Guide rods 10 are respectively fixedly connected to one side walls of the two sliding blocks 9. One ends of the two guide rods 10 respectively penetrate through the two positioning plates 2 and are fixedly connected with anti-disengagement parts, and the two guide rods 10 are respectively slidably connected to the two positioning plates 2;

[0027] By adopting the above case, through the cooperation of the sliding grooves 3, the sliding blocks 9, the guide rods 10 and the anti-disengagement parts, the sample storage rack 4 can be easily pulled out from the inside of the storage box 1, so that it is convenient for the experimenter to take or store the chromatin immunoprecipitation sample;

[0028] A U-shaped supporting plate 11 is fixedly connected to the bottom of the sample storage rack 4. A plurality of supporting pads 12 are fixedly connected to the inner bottom of the U-shaped supporting plate 11. The plurality of supporting pads 12 are respectively located directly below the plurality of receiving grooves 5. By setting the cooperation of the U-shaped supporting plate 11 and the supporting pads 12, it plays a role in protecting the bottom of the sample tube 6, avoiding the bottom of the sample tube 6 from being knocked and damaged, so as to avoid the chromatin immunoprecipitation sample from flowing out and causing waste and pollution;

[0029] A refrigeration device body 13 is fixedly installed at the bottom of the storage box 1, and the refrigeration end of the refrigeration device body 13 is located inside the storage box 1. A temperature sensor 14 is fixedly connected to the inner top of the storage box 1. Lights 15 are fixedly connected to the inner walls on both sides of the storage box 1 respectively. A control panel 16 is fixedly installed on one side wall of the storage box 1. The refrigeration device body 13, the temperature sensor 14 and the light 15 are all electrically connected to the control panel 16 through wires. The circuit connection is an existing mature technology. The specific connection method and working principle are no longer repeated here. The refrigeration device body 13, the temperature sensor 14 and the light 15 can be started and stopped through the control panel 16. By setting the temperature sensor 14, the temperature inside the storage box 1 is monitored in real time, so that the temperature can be controlled within a suitable range. By setting the light 15, it is convenient for experimenters to observe the storage status of the chromatin immunoprecipitation sample. A sealing door is hinged on one side of the storage box 1 to provide good sealing for the storage box 1, ensuring that the chromatin immunoprecipitation sample is not affected by the external ambient temperature during storage.

[0030] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A chromatin immunoprecipitation sample storage device, comprising a storage box (1), characterized in that: On the inner walls of both sides of the storage box (1), positioning plates (2) are respectively and fixedly installed. On the opposite side walls of the two groups of positioning plates (2), sliding grooves (3) are respectively opened. And between the two groups of positioning plates (2), a sample storage rack (4) is arranged. On the top of the sample storage rack (4), a number of accommodation grooves (5) are opened. Inside the number of accommodation grooves (5), sample tubes (6) are respectively arranged. And on both sides of the inner walls of the number of accommodation grooves (5), clamping assemblies (7) which can be adaptively adjusted to clamp and position the sample tubes (6) are respectively arranged.

2. A chromatin immunoprecipitation sample storage device according to claim 1, characterized in that: The clamping assembly (7) includes a让位槽 (701) which is opened on the inner wall of the accommodation groove (5). On one side inner wall of the让位槽 (701), a return spring (702) is fixedly connected. One end of the return spring (702) is fixedly connected with a sliding column (703). One end of the sliding column (703) is fixedly connected with a clamping plate (704).

3. A chromatin immunoprecipitation sample storage device according to claim 2, characterized in that: The sliding column (703) is slidably inserted into the inside of the让位槽 (701). And on one side wall of the clamping plate (704), a V-shaped groove (8) is opened.

4. A chromatin immunoprecipitation sample storage device according to claim 1, characterized in that: On both side walls of the sample storage rack (4), sliding blocks (9) which are adapted to the sliding grooves (3) are respectively fixedly connected. The two groups of sliding blocks (9) are respectively slidably connected to the inside of the two groups of sliding grooves (3).

5. A chromatin immunoprecipitation sample storage device according to claim 4, characterized in that: On one side walls of the two groups of sliding blocks (9), guide rods (10) are respectively fixedly connected. One ends of the two groups of guide rods (10) respectively penetrate through the two groups of positioning plates (2) and are fixedly connected with anti-disengagement parts. And the two groups of guide rods (10) are respectively slidably connected with the two groups of positioning plates (2).

6. A chromatin immunoprecipitation sample storage device according to claim 1, characterized in that: At the bottom of the sample storage rack (4), a U-shaped supporting plate (11) is fixedly connected. On the inner bottom of the U-shaped supporting plate (11), a number of supporting pads (12) are fixedly connected. The number of supporting pads (12) are respectively located directly below the number of accommodation grooves (5).

7. A chromatin immunoprecipitation sample storage device according to claim 1, characterized in that: At the bottom of the storage box (1), a refrigeration device body (13) is fixedly installed. On the inner top of the storage box (1), a temperature sensor (14) is fixedly connected. On the inner walls of both sides of the storage box (1), lighting lamps (15) are respectively fixedly connected. On one side wall of the storage box (1), a control panel (16) is fixedly installed. The refrigeration device body (13), the temperature sensor (14) and the lighting lamps (15) are all electrically connected to the control panel (16) through wires.