Waste discharge needle structure of cell filtering equipment

Abstract

The utility model relates to a waste discharge needle structure of cell filtering equipment, which comprises a filter used for separating sample cells to be detected; the waste discharge assembly comprises an inserting part, a connecting part and a waste discharge part, the inserting part is communicated with the waste discharge part through the connecting part, and the inserting part is arranged on the filter; the pressure detection joint is arranged on the waste discharge part; the connecting piece is arranged between the connecting part and the pressure detection connector; the insertion part is communicated with the filter, the waste discharge part is combined with the waste discharge pump at the pressure detection connector and extends into the waste discharge pump, meanwhile, the connecting part and the pressure detection connector are connected through the connecting piece, a closed pipeline with the pressure detection connector externally connected to air pressure monitoring is constructed, and external measurement of components for pressure detection of the filter is achieved. The influence of discharged waste liquid backflow on pressure detection component measurement is avoided, and normal discharge of waste liquid is ensured.

Description

Technical Field

[0001] The utility model relates to the field of biotechnology, in particular to a waste discharge needle structure of a cell filtering device. Background Art

[0002] CTCs detection is a new type of non-invasive diagnostic tool. CTCs enrichment is usually required before detection. Existing CTCs enrichment methods are mainly divided into immunomagnetic separation method and enrichment method based on the physical properties of CTCs according to their principles. The enrichment method based on the physical properties of CTCs mainly consists of density gradient centrifugation and filtration method. Among them, the filtration method is a separation method based on the size of tumor cells. The cell morphology separated by physical methods is intact, and various antigens or molecular markers on the surface are not destroyed, which does not affect the characteristics of the cells, providing good conditions for subsequent detection.

[0003] At present, the filtration method usually uses a combination of a cell filter and a negative pressure pump. A cavity structure is constructed in between, and an external pressure detection instrument is connected to perform pressure detection during the separation and liquid discharge process to avoid air leakage and liquid leakage that may cause the equipment to misjudge the pressure in the cell filter and affect the experimental organization. Since the waste liquid discharged from the filter will flow through the cavity into the connection of the pressure detection instrument, it will affect the normal monitoring of the instrument and assist the filter in waste discharge. Utility Model Content

[0004] Based on the above description, the utility model provides a waste discharge needle structure for a cell filtration device to solve the problem that excessive discharge of waste liquid may affect the use of a pressure detection instrument.

[0005] The technical solution of the utility model to solve the above technical problems is as follows:

[0006] A waste discharge needle structure of a cell filtration device, comprising:

[0007] A filter, which is used to separate cells from the sample to be tested;

[0008] A waste discharge assembly, comprising a plug-in portion, a connecting portion and a waste discharge portion, wherein the plug-in portion is connected to the waste discharge portion through the connecting portion, and the plug-in portion is arranged on the filter;

[0009] A pressure detection joint, which is arranged on the waste discharge part;

[0010] On the basis of the above technical solution, the present invention can also be improved as follows.

[0011] Furthermore, the pressure detection joint includes a connecting pipe, and the connecting pipe is provided with interface 1 and interface 2, the interface 1 is symmetrically distributed on both ends of the connecting pipe, and the interface 2 is arranged outside the connecting pipe.

[0012] Furthermore, one end of the waste discharge part passes through a connecting pipe through an interface, and a gap is left between the waste discharge part and the connecting pipe.

[0013] Furthermore, the connecting piece includes a sleeve arranged between the connecting portion and the connecting pipe, and a clamp is arranged on the connecting end of the sleeve.

[0014] Compared with the prior art, the technical solution of this application has the following beneficial technical effects:

[0015] The utility model provides a filter, a waste discharge part, a pressure detection joint and a connecting piece, the filter is connected through the plug-in part, the waste discharge part is combined with the waste discharge pump at the pressure detection joint and extends into the waste discharge pump, and at the same time the connecting piece connects the connecting part and the pressure detection joint, constructs a closed pipeline for air pressure monitoring connected to the pressure detection joint, realizes external measurement of the component for filter pressure detection, avoids the backflow of discharged waste liquid affecting the measurement of the pressure detection component, and ensures the normal discharge of waste liquid. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 A schematic diagram of a waste discharge needle structure of a cell filtration device provided in an embodiment of the utility model;

[0017] Figure 2 This is a schematic diagram of the connection structure between the waste discharge part and the connecting pipe in the embodiment of the utility model;

[0018] In the accompanying drawings, the components represented by the reference numerals are listed as follows:

[0019] 1. Filter; 2. Waste discharge assembly; 21. Plug-in portion; 22. Connecting portion; 23. Waste discharge portion; 3. Pressure detection connector; 4. Connecting piece. DETAILED DESCRIPTION

[0020] In order to facilitate understanding of the present application, the present application will be described more fully below with reference to the relevant drawings. Embodiments of the present application are provided in the drawings. However, the present application can be implemented in many different forms and is not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to make the disclosure of the present application more thorough and comprehensive.

[0021] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art to which this application belongs. The terms used herein in the specification of this application are only for the purpose of describing specific embodiments and are not intended to limit this application.

[0022] It will be appreciated that spatial relationship terms such as "under", "beneath", "below", "under", "above", "above", etc., may be used herein to describe the relationship of an element or feature shown in the figures to other elements or features. It should be understood that in addition to the orientations shown in the figures, spatial relationship terms also include different orientations of the device in use and operation. For example, if the device in the accompanying drawings is flipped, the element or feature described as "under other elements" or "under it" or "under it" will be oriented as "on" the other elements or features. Therefore, the exemplary terms "under" and "under" may include both upper and lower orientations. In addition, the device may also include additional orientations (e.g., rotated 90 degrees or other orientations), and the spatial descriptors used herein are interpreted accordingly.

[0023] See also Figure 1-2 A waste discharge needle structure of a cell filtration device includes a filter 1, a waste discharge component 2, a pressure detection connector 3, a connecting piece 4 and a limiting piece 5. The waste discharge component 2 includes a plug-in portion 21 arranged on the filter 1, a connecting portion 22 is arranged on the plug-in portion 21, a waste discharge portion 23 is arranged on the connecting portion 22, the pressure detection connector 3 is arranged on the waste discharge portion 23, the connecting piece 4 is arranged between the connecting portion 22 and the pressure detection connector 3, and the limiting piece 5 is arranged on the connecting piece 4.

[0024] Based on the above, in this embodiment, the waste discharge pump pipeline is externally connected through the pressure detection connector 4, and the waste discharge part 23 is extended into the waste discharge pump pipeline. At the same time, the pressure detection connector 3 is combined with the connecting part 22 through the connecting piece 4 to construct a closed pipeline in which the pressure detection connector 3 is externally connected to the barometer. In this way, the filter 1 discharges the filtered liquid under the action of the waste discharge pump, and flows out through the plug-in part 21, the connecting part 22 and the waste discharge part 23. The barometer monitors the waste discharge pressure through the pressure detection connector 3, realizes the external measurement of the pressure detection component of the filter, avoids the backflow of the discharged waste liquid affecting the measurement of the pressure detection component, and ensures the normal discharge of the waste liquid.

[0025] See also Figure 1-2 The pressure detection joint 3 includes a connecting pipe, on which an interface 1 and an interface 2 are provided. The interface 1 is symmetrically distributed on both ends of the connecting pipe, and the interface 2 is distributed side by side outside the connecting pipe. One end of the waste discharge part 23 passes through the connecting pipe through the interface 1, and a gap is left between the waste discharge part 23 and the connecting pipe.

[0026] It should be noted that the waste discharge assembly 2 of this embodiment is a welded stainless steel structure, which is divided into a plug-in portion 21 of the needle part, a connecting piece 22 with a pagoda structure connected to the connecting piece 4, and a waste discharge portion 23 that serves as an extension of the needle tube of the plug-in portion 21.

[0027] Based on the above, the connecting pipe is connected to the outside of the waste discharge part 23 through a set of interfaces, and there is a gap between the waste discharge part 23 and the connecting pipe. The side of the interface 2 is connected to the connecting pipe, so that the connecting pipe is connected to the waste discharge pump pipeline, and the extended waste discharge part 23 is extended into the waste discharge pump pipeline, which can prevent the filtered waste liquid discharged from the filter 1 from flowing back into the connecting pipe 3. The waste discharge part 23 and the present embodiment are provided with two interfaces 2, one of which is connected to the pipeline of the pressure gauge to monitor the internal pressure of the filter 1, and the other is connected to the pressure relief valve pipeline. When the pressure gauge detects that the internal pressure of the filter 1 is too high, the pressure relief valve can be operated to balance the internal pressure of the filter 1 to ensure that the filter 1 discharges the waste liquid normally.

[0028] See also Figure 1-2 The connecting member 4 includes a sleeve disposed between the connecting portion 22 and the connecting pipe, and a clamp is disposed on the connecting end of the sleeve;

[0029] The above-mentioned connector 4 is connected to the connector 22 and the connecting pipe. Both ends of the sleeve are flared and the sleeve is slightly longer. During installation, the sleeve is first passed through the waste discharge part 23 and pressed into the connector 22 through the flaring. Then the connecting pipe is passed through the waste discharge part 23 through the interface 1 and then pressed into the sleeve through the flaring. In this way, the sleeve is closed on the four-way formed by the interface 1 and the interface 2, constructing a closed space for the pressure gauge detection connected to the interface 2. When the filter 1 is blocked, the waste discharge part 23, the connecting pipe and the waste discharge pump are all under negative pressure. The pressure gauge monitors the air pressure change and displays it, and feeds back the working condition of the filter 1 to the staff.

[0030] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A waste discharge needle structure for a cell filtration device, characterized in that: include A filter (1) is used to separate cells from a sample to be tested; A waste discharge assembly (2), comprising a plug-in portion (21), a connecting portion (22) and a waste discharge portion (23), wherein the plug-in portion (21) is connected to the waste discharge portion (23) via the connecting portion (22), and the plug-in portion (21) is arranged on the filter (1); A pressure detection joint (3) disposed on the waste discharge portion (23); A connecting piece (4) is arranged between the connecting portion (22) and the pressure detection joint (3).

2. The waste discharge needle structure of the cell filtration device according to claim 1, characterized in that: The pressure detection joint (3) comprises a connecting pipe, on which a first interface and a second interface are arranged, wherein the first interface is symmetrically distributed at both ends of the connecting pipe, and the second interface is arranged outside the connecting pipe.

3. The waste discharge needle structure of the cell filtration device according to claim 2, characterized in that: One end of the waste discharge portion (23) passes through a connecting pipe via an interface 1, and a gap is left between the waste discharge portion (23) and the connecting pipe.

4. The waste discharge needle structure of the cell filtration device according to claim 2, characterized in that: The connecting piece (4) comprises a sleeve arranged between the connecting portion (22) and the connecting pipe, and a clamp is arranged on the connecting end of the sleeve.

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