Mouse saliva collector

By designing the mouse temporary storage box and aroma dissipation components, using the mice's love for fragrance bait, the mouse saliva collection without anesthesia and binding is achieved, solving the problems of harm and bite risks to mice in the existing methods, and improving the safety and efficiency of the collection process.

CN222622997UActive Publication Date: 2025-03-18WUHAN XIANRAN BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202421029844.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-13
Publication Date
2025-03-18
Estimated Expiration
2034-05-13

AI Technical Summary

Technical Problem

Existing methods for collecting saliva in mice require anesthesia and binding, which can easily lead to struggle, bite and harm to mice.

Method used

A mouse saliva collector was designed, including a mouse temporary storage box, aroma dissipation assembly and air conduit fittings. By putting in the incense bait in the mouse temporary storage box, the fragrance is guided into the saliva collection capsule by using the air guide tube fittings, attracting the mice to actively chew, thus leaving saliva.

Benefits of technology

The safe and effective collection of mouse saliva without anesthesia and binding is achieved, avoiding the risk of harm and bite to mice, while simplifying the saliva collection process.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a mouse saliva collector, and belongs to the technical field of biological experiments. The mouse temporary storage device comprises a mouse temporary storage box, a top opening is formed in the top of the mouse temporary storage box, the mouse temporary storage device further comprises a gate inserted from the top of the mouse temporary storage box, a fragrance emitting assembly is arranged at the top of the mouse temporary storage box, and an air guide pipe penetrating through the top opening to extend into the mouse temporary storage box is arranged on one side of the fragrance emitting assembly. The air guide pipe fitting comprises a guide pipe movably connected with the fragrance emitting assembly and a clamping pipe arranged at the lower end of the guide pipe, a saliva collecting bag is arranged on the inner side of the clamping pipe, and the saliva collecting bag comprises an inner framework and a cotton bag wrapping the surface of the inner framework. According to the mouse saliva collecting device, the mouse saliva can be collected on the premise that the mouse is not hurt, the mouse actively leaves the saliva, the mouse does not generate the resistant emotion, the mouse saliva can be repeatedly extracted conveniently, the saliva collecting bag can be rapidly taken down from the clamping pipe, and operation is easy and rapid.
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Description

Technical Field

[0001] The utility model belongs to the technical field of biological experiments, and particularly relates to a mouse saliva collector. Background Art

[0002] Animal models are indispensable tools in biomedical research. In experiments to study salivary gland diseases, it is usually necessary to collect saliva from the salivary glands of experimental animals. Mice are commonly used animals for animal experiments. The current process of collecting mouse saliva is to use elastic rubber bands to tie the mouse's limbs to a board with nails at the four corners, then hang the rubber bands on the mouse's upper teeth, lift the rubber bands upward to lift the mouse's head to keep the mouth open, and then use a pipette to reach into the mouse's mouth to extract saliva. This method requires the mouse's limbs to be tied and fixed after anesthesia. Otherwise, it is easy for the mouse to struggle and cause difficulty in tying and fixing. There is also a risk of the mouse biting the experimenter, and it is easy to cause harm to the mouse itself. Summary of the invention

[0003] The utility model aims to provide a mouse saliva collector to solve the problems existing in the prior art, so as to avoid the problem that mice bite experimenters and cause harm to the mice themselves.

[0004] To achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a mouse saliva collector, including a mouse temporary storage box, a top opening is opened on the top of the mouse temporary storage box, and also includes a gate inserted from the top of the mouse temporary storage box, a fragrance dispersing component is provided on the top of the mouse temporary storage box, and a wind guide pipe is provided on one side of the fragrance dispersing component, which passes through the top opening and extends to the interior of the mouse temporary storage box, and the wind guide pipe includes a conduit movably connected to the fragrance dispersing component and a clamping tube arranged at the lower end of the conduit, a saliva collection bag is provided on the inner side of the clamping tube, and the saliva collection bag includes an inner skeleton and a cotton bag wrapped on the surface of the inner skeleton.

[0005] After the mice are put into the mouse storage box, the scented bait is put into the aroma dispersing component. The aroma enters the saliva collecting bag through the air duct, so that the saliva collecting bag emits aroma in the mouse storage box to lure the mice. The mice can't help but gnaw on the saliva collecting bag. In the process of the mice gnawing, the saliva in the mouse's mouth will remain on the cotton bag. After the researchers disassemble the air duct and the aroma dispersing component, the saliva collecting bag stained with mouse saliva can be taken out from the top, and then the saliva collecting bag is removed from the clamp tube and put into a test tube containing reagents to complete the collection of mouse saliva. The whole process uses inducement to make the mice actively leave saliva, which will not cause harm to the mice and will not make them resist, making it convenient to repeatedly extract mouse saliva.

[0006] Optionally, an observation port is provided at one end of the mouse temporary storage box away from the gate, and an observation window is bonded to the inner wall of the observation port.

[0007] Through the observation window, researchers can observe the status of mice at any time and grasp the timing of removing the saliva collection bag in time to reduce the time that the mouse saliva stays in the outside world, thereby ensuring the purity of the mouse saliva as much as possible. In addition, by opening a small window, the researcher's exposure to the mouse's line of sight can be reduced, thereby allowing the mouse to let down its vigilance earlier to a certain extent, making it easier to lure the mouse.

[0008] Optionally, the fragrance dissemination component includes a storage box fixed on the top surface of the mouse temporary storage box, the storage box is filled with fragrant bait, and a top cover is provided on the top of the storage box.

[0009] The bait should be food that mice like and can be put directly into the storage box.

[0010] Optionally, the fragrance dispersing component further comprises a wind tube arranged on the side wall of the storage box, the wind tube is connected to the storage box, and a small fan is arranged inside the wind tube.

[0011] Use a hair dryer to blow air into the storage box to speed up the dissipation of the scent of the bait.

[0012] Optionally, the fragrance dispensing component further includes a three-pronged pipe connected to the storage box, and the three-pronged pipe includes an air outlet pipe connected to the storage box and a bifurcated pipe connected to the other end of the air outlet pipe.

[0013] The wind force of the hair dryer is dispersed through the bifurcated tube, the wind strength is weakened, and the scented air is allowed to enter the saliva collection bag more naturally.

[0014] Optionally, the top end of the catheter is sleeved with one end of the bifurcated tube via a docking joint.

[0015] The docking connector allows researchers to easily disassemble the catheter and bifurcated tube.

[0016] Optionally, the clamp tube is a C-shaped elastic plastic tube, the lower end of the catheter is connected to the middle of the clamp tube, and both ends of the clamp tube are fixedly mounted with plug plates inserted into the saliva collection bag.

[0017] By using a C-shaped elastic plastic tube, the saliva collection bag can be clamped by relying on the elastic force of the clamp tube itself, which is convenient for installing the saliva collection bag and also convenient for removing the saliva collection bag.

[0018] Optionally, the plug plate is a hollow "convex" plate, the outer diameter of the plug plate is larger than the inner diameters of both ends of the saliva collection bag, and the clamping tube is connected to the saliva collection bag through the plug plate.

[0019] Use the plug plate to insert the two ends of the saliva collection bag to make the connection between the saliva collection bag and the clamp tube more stable.

[0020] Optionally, the saliva collection bag is a hollow columnar body that is thin at both ends and thick in the middle, and a plurality of air-permeable pores are provided on the surface of the cotton bag.

[0021] The saliva collecting sac, which is thin at both ends and thick in the middle, makes it easier for mice to get saliva on their food when they gnaw on it. At the same time, the breathable holes allow the fragrance to be emitted from the inside of the saliva collecting sac.

[0022] Compared with the prior art, the beneficial effects of the utility model are: 1. By allowing mice to actively gnaw on the saliva collecting capsule, the mouse saliva is stained on the saliva collecting capsule, and the researcher has no contact with the mouse, making it safer for the researcher to collect the mouse saliva, and will not cause harm to the mouse; 2. Put the scented bait into the fragrance dissemination component, and use the air guide pipe to introduce the fragrance of the scented bait into the saliva collecting capsule, so that the scented bait can be used repeatedly; 3. The wind force of the air duct is dispersed through the bifurcated tube to weaken the wind strength, so that the scented air can enter the saliva collecting capsule more naturally; 4. The researcher can disassemble the catheter and the bifurcated tube more easily through the docking joint; 5. The saliva collecting capsule is clamped by the elastic force of the clamping tube itself, which is convenient for installing the saliva collecting capsule and removing the saliva collecting capsule; 6. The saliva collecting capsule adopts an inner skeleton as a support, and cotton is wrapped on the surface of the inner skeleton to form a cotton capsule, so that the saliva collecting capsule will not be easily damaged, but can be easily stained with mouse saliva, making saliva collection simpler. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 This is a schematic diagram of the utility model from the front side and from a top view;

[0024] Figure 2 This is a schematic diagram of the utility model from a rear top view;

[0025] Figure 3 For this utility model Figure 2 The enlarged schematic diagram at A in the middle;

[0026] Figure 4 It is a schematic cross-sectional view of the utility model;

[0027] Figure 5 This is a schematic diagram of the connection state of the clamp tube and the saliva collection bag of the utility model;

[0028] Figure 6 It is a cross-sectional schematic diagram of the saliva collection bag of the utility model.

[0029] In the figure: 1. Mouse temporary storage box; 2. Gate; 3. Observation window; 4. Top opening;

[0030] 5. Aroma dissemination component; 51. Storage box; 52. Top cover; 53. Air duct; 54. Three-pronged pipe; 541. Air outlet pipe; 542. Forked pipe;

[0031] 6. Air guide pipe; 61. Conduit; 62. Butt joint; 63. Clamp pipe; 64. Insert plate;

[0032] 7. Saliva collection bag; 71. Internal skeleton; 72. Cotton bag. DETAILED DESCRIPTION

[0033] The following will be combined with the drawings in the utility model to clearly and completely describe the technical solution of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0034] In the description of the present invention, it should be noted that the directions or positional relationships indicated by terms such as "middle", "upper", "lower", "left", "right", "inside" and "outside" are based on the directions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation on the present invention.

[0035] like Figure 1 As shown, the specific scheme of the embodiment is as follows: a mouse saliva collector includes a mouse temporary storage box 1, a top opening 4 is opened on the top of the mouse temporary storage box 1, and also includes a gate 2 inserted from the top of the mouse temporary storage box 1, an observation port is opened at one end of the mouse temporary storage box 1 away from the gate 2, and an observation window 3 is bonded to the inner wall of the observation port.

[0036] It should be noted here that the observation port is located at the upper part of the mouse temporary storage box 1, which is higher than the mouse, and the mouse temporary storage box 1 itself is opaque. When the mouse is locked in the mouse temporary storage box 1, the inside of the mouse temporary storage box 1 is not in a dark environment because the observation window 3 and the top port 4 can transmit light, but the mouse cannot see the researcher standing outside the mouse temporary storage box 1. This can reduce the range of the researcher exposed to the mouse's line of sight, so as to a certain extent, the mouse can be lowered earlier, and then it is convenient to lure the mouse.

[0037] The researcher can observe the state of the mouse at any time through the observation window 3 and timely grasp the timing of taking out the saliva collection capsule 7 to reduce the time that the mouse saliva stays in the outside world, thereby ensuring the purity of the mouse saliva as much as possible.

[0038] See also Figure 1-6In this embodiment, an aroma dispersing component 5 filled with scented bait for emitting aroma to attract mice is provided on the top of the mouse temporary storage box 1. An air guide duct 6 is provided on one side of the aroma dispersing component 5 and extends through the top opening 4 to the inside of the mouse temporary storage box 1 for transporting aroma. The air guide duct 6 includes a conduit 61 movably connected to the aroma dispersing component 5 and a clamping tube 63 arranged at the lower end of the conduit 61. A saliva collecting bag 7 is provided on the inner side of the clamping tube 63 for inducing mice to actively gnaw and leave saliva. The saliva collecting bag 7 includes an inner skeleton 71 and a cotton bag 72 wrapped on the surface of the inner skeleton 71.

[0039] After the mice are locked in the mouse temporary storage box 1, fragrant bait is put into the fragrance distributing component 5, and the fragrance enters the saliva collecting capsule 7 through the air guide pipe 6, so that the saliva collecting capsule 7 emits fragrance in the mouse temporary storage box 1 to lure the mice, making them unable to resist gnawing on the saliva collecting capsule 7. During the gnawing process, the saliva in the mouse's mouth will remain on the cotton bag 72. After the researchers disassemble the air guide pipe 6 and the fragrance distributing component 5, the saliva collecting capsule 7 stained with the mouse's saliva can be taken out from the top opening 4, and then the saliva collecting capsule 7 is removed from the clamp tube 63 and put into a test tube filled with reagents to complete the collection of the mouse's saliva. The whole process uses the method of inducement to make the mice actively leave saliva, which will not only not cause harm to the mice, but also will not make the mice resist, and it is convenient to repeatedly extract the mouse's saliva.

[0040] See also Figure 1 The aroma dissemination component 5 includes a storage box 51 fixed on the top surface of the mouse temporary storage box 1, the storage box 51 is filled with fragrant bait, and the top of the storage box 51 is provided with a top cover 52. The fragrant bait is selected from the favorite food of mice and can be directly put in from the top of the storage box 51.

[0041] The aroma dispersing assembly 5 further comprises a wind tube 53 arranged on the side wall of the storage box 51, the wind tube 53 is connected with the storage box 51, and a small fan is arranged inside the wind tube 53. The wind tube 53 is used to fill the storage box 51 with air to accelerate the speed of the scent of the bait to be dispersed.

[0042] The fragrance dispensing assembly 5 further includes a three-pronged pipe 54 connected to the storage box 51 . The three-pronged pipe 54 includes an air outlet pipe 541 connected to the storage box 51 and a bifurcated pipe 542 connected to the other end of the air outlet pipe 541 .

[0043] The wind force of the air tube 53 is dispersed through the bifurcated tube 542 to reduce the wind force, allowing the scented air to enter the saliva collection bag 7 more naturally.

[0044] The top end of the catheter 61 is sleeved with one end of the bifurcated tube 542 through a butt joint 62. The butt joint 62 allows researchers to disassemble the catheter 61 and the bifurcated tube 542 more easily.

[0045] Please refer to 4-5, the clamp tube 63 is a C-shaped elastic plastic tube, the lower end of the catheter 61 is connected to the middle of the clamp tube 63, and both ends of the clamp tube 63 are fixedly installed with plug plates 64 inserted into the saliva collection bag 7.

[0046] By using a C-shaped elastic plastic tube, the saliva collecting bag 7 can be clamped by the elastic force of the clamping tube 63 itself, which is convenient for installing the saliva collecting bag 7 and also convenient for removing the saliva collecting bag 7.

[0047] The inserting plate 64 is a hollow “convex” plate, the outer diameter of the inserting plate 64 is larger than the inner diameters of the two ends of the saliva collecting bag 7 , and the clamping tube 63 is connected to the saliva collecting bag 7 through the inserting plate 64 .

[0048] The inserting plates 64 are inserted into the two ends of the saliva collecting bag 7 to make the connection between the saliva collecting bag 7 and the clamping tube 63 more stable.

[0049] See also Figure 5-6 The saliva collecting bag 7 is a hollow columnar body with thin ends and thick middle, and a plurality of ventilation holes are provided on the surface of the cotton bag 72. The thin ends and thick middle saliva collecting bag 7 make it easier for mice to get saliva on them when they gnaw on them. At the same time, the ventilation holes provide convenience for fragrance to be emitted from the inside of the saliva collecting bag 7.

[0050] Working principle: Put the scented bait into the storage box 51, and the fragrance emitted by the scented bait is introduced into the catheter 61 through the air duct 53, and then enters the saliva collecting capsule 7, so that the saliva collecting capsule 7 emits fragrance in the mouse temporary storage box 1, thereby luring the mice and making them unable to help but gnaw on the saliva collecting capsule 7. During the gnawing process of the mice, the saliva in the mouth of the mice will remain on the cotton bag 72. After the researchers disassemble the air guide duct 6 and the fragrance dispensing component 5, the saliva collecting capsule 7 stained with the mouse saliva is taken out from the top opening 4, and then the saliva collecting capsule 7 is removed from the clamp tube 63 and put into a test tube filled with reagents. That is, the collection of mouse saliva can be completed without any harm to the mice themselves and without the mice biting the researchers.

[0051] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A mouse saliva collector, characterized in that: The invention comprises a mouse temporary storage box (1), wherein the top of the mouse temporary storage box (1) is provided with a top opening (4), and further comprises a gate (2) inserted from the top of the mouse temporary storage box (1), wherein the top of the mouse temporary storage box (1) is provided with a fragrance dispensing component (5), and one side of the fragrance dispensing component (5) is provided with an air guide pipe (6) passing through the top opening (4) and extending into the interior of the mouse temporary storage box (1), wherein the air guide pipe (6) comprises a conduit (61) movably connected to the fragrance dispensing component (5) and a clamping pipe (63) arranged at the lower end of the conduit (61), wherein a saliva collecting bag (7) is arranged on the inner side of the clamping pipe (63), and wherein the saliva collecting bag (7) comprises an inner frame (71) and a cotton bag (72) wrapped on the surface of the inner frame (71).

2. A mouse saliva collector according to claim 1, characterized in that: The mouse temporary storage box (1) is provided with an observation port at one end away from the gate (2), and an observation window (3) is bonded to the inner wall of the observation port.

3. A mouse saliva collector according to claim 1, characterized in that: The fragrance emitting component (5) comprises a storage box (51) fixed on the top surface of the mouse temporary storage box (1), the storage box (51) contains fragrant bait, and the top of the storage box (51) is provided with a top cover (52).

4. A mouse saliva collector according to claim 3, characterized in that: The fragrance dispersing assembly (5) further comprises a wind tube (53) arranged on a side wall of the storage box (51); the wind tube (53) is connected to the storage box (51); and a small fan is arranged inside the wind tube (53).

5. A mouse saliva collector according to claim 3, characterized in that: The fragrance dispersing assembly (5) further comprises a three-pronged pipe (54) connected to the storage box (51), wherein the three-pronged pipe (54) comprises an air outlet pipe (541) connected to the storage box (51) and a bifurcated pipe (542) connected to the other end of the air outlet pipe (541).

6. A mouse saliva collector according to claim 5, characterized in that: The top end of the catheter (61) is sleeved with one end of the bifurcated tube (542) via a docking joint (62).

7. A mouse saliva collector according to claim 1, characterized in that: The clamp tube (63) is a C-shaped elastic plastic tube. The lower end of the catheter (61) is connected to the middle of the clamp tube (63). Both ends of the clamp tube (63) are fixedly mounted with plug plates (64) that are inserted into the interior of the saliva collection bag (7).

8. A mouse saliva collector according to claim 7, characterized in that: The insert plate (64) is a hollow "convex" plate, the outer diameter of the insert plate (64) is larger than the inner diameters of the two ends of the saliva collection bag (7), and the clamp tube (63) is connected to the saliva collection bag (7) through the insert plate (64).

9. A mouse saliva collector according to claim 1, characterized in that: The saliva collection bag (7) is a hollow columnar body that is thin at both ends and thick in the middle. The surface of the cotton bag (72) is provided with a plurality of air-permeable pores.