Temperature control module

Abstract

The utility model provides a temperature control module, which is used for accommodating a sliding chip and controlling the temperature of the sliding chip and comprises a fixing device and a heater. The fixing device comprises a first frame-shaped part and a second frame-shaped part which are oppositely arranged in parallel from top to bottom, the surface of the side, facing the second frame-shaped part, of the first frame-shaped part is provided with a concave first containing space, and the peripheral side edge of the first containing space is used for being embedded with an upper chip part of the sliding chip. The surface of the side, facing the first frame-shaped part, of the second frame-shaped part is provided with a concave second containing space, and the peripheral side edge of the second containing space is used for being embedded with the lower chip part of the sliding chip. The heater is at least partially arranged on the bottom face of the second containing space, and the heater is transparent. Corresponding to the observation area of the sliding chip, the upper surface of the first frame-shaped part is provided with a first through part penetrating downwards to the bottom surface of the first accommodating space, and the lower surface of the second frame-shaped part is provided with a second through part penetrating upwards to the bottom surface of the second accommodating space.

Description

Technical Field

[0001] The utility model relates to the technical field of life science instruments, in particular to a temperature control module. Background Art

[0002] When using the SlipChip for bacterial resistance testing, it is necessary to first use microfluidics to distribute the sample to be tested into the reaction chamber of the SlipChip, then control the temperature of the bacterial culture, and culture the bacteria in the SlipChip. Since the SlipChip is composed of multiple injection-molded plates or glass plates, a special fixture needs to be customized to ensure the stability of the SlipChip. At the same time, since the SlipChip is not horizontal and smooth, the structure of the fixture needs to fit the SlipChip and have good thermal conductivity to ensure a suitable temperature for bacterial culture. In drug resistance testing, it is necessary to take photos and record the bacterial cells being cultured at regular intervals. In order to obtain more information, fluorescence detection is often required, which requires that the temperature control device must be transparent as a whole so that the light from the bottom illumination can pass through the SlipChip to convey appropriate information. However, most of the existing temperature control devices are opaque, which will lead to reduced detection accuracy, and the existing fixture cannot add reagents to the SlipChip in a fixed state, which reduces the detection efficiency. Utility Model Content

[0003] The technical problem to be solved by the utility model is to provide a temperature control module in order to overcome the defect of low accuracy of bacterial drug resistance detection using a sliding chip in the prior art.

[0004] The utility model solves the above technical problems through the following technical solutions:

[0005] A temperature control module, used to accommodate a slip chip and control the temperature of the slip chip, the temperature control module comprising:

[0006] A fixing device, the fixing device comprising a first frame-shaped portion and a second frame-shaped portion arranged relatively parallel to each other in a top-to-bottom direction, the surface of the first frame-shaped portion facing the second frame-shaped portion having a first concave accommodation space, the peripheral side edge of the first accommodation space being used to fit with the upper chip portion of the slip chip, the surface of the second frame-shaped portion facing the first frame-shaped portion having a second concave accommodation space, the peripheral side edge of the second accommodation space being used to fit with the lower chip portion of the slip chip;

[0007] a heater, the heater being disposed on the bottom surface of the second receiving space and being transparent;

[0008] Corresponding to the observation area of ​​the slip chip, a first through portion penetrating downward to the bottom surface of the first accommodation space is provided on the upper surface of the first frame-shaped portion, and a second through portion penetrating upward to the bottom surface of the second accommodation space is provided on the lower surface of the second frame-shaped portion.

[0009] In the present technical solution, a fixing device is provided to accommodate the slip chip in a clamping manner to achieve reliable connection and positioning of the slip chip, and a transparent heater is further provided on the lower surface of the second frame-shaped portion to be clamped by the fixing device together with the slip chip, thereby providing a reliable fixing solution for a transparent heater whose material is softer than that of an opaque heater.

[0010] When the heater is transparent, a first through portion and a second through portion are respectively provided on the first frame portion and the second frame portion, so that light can penetrate the second frame portion, the transparent heater, the observation area of ​​the slip chip, and the first frame portion from bottom to top, thereby making it possible to observe the slip chip by visible light observation means such as a microscope, thereby improving the detection accuracy when the slip chip is used for detection.

[0011] Preferably, the first frame-shaped portion and the second frame-shaped portion are detachably connected, and the first frame-shaped portion and the second frame-shaped portion can slide along a sliding direction of the slip chip.

[0012] In the present technical solution, the first frame-shaped portion and the second frame-shaped portion can also slide along the sliding direction of the slip chip, so as to achieve the purpose of driving the slip chip to slide by sliding of the fixing device, so that the slip chip can slide when being fixed in the fixing device, thereby meeting the operation requirements of related experiments.

[0013] Preferably, the first frame portion has at least four through holes, the second frame portion has at least four long waist holes extending along the sliding direction, the through holes and the long waist holes are arranged in a one-to-one correspondence, and the first frame portion and the second frame portion are penetrated by screws in the through holes and the long waist holes to achieve the first frame portion and the second frame portion being able to slide along the sliding direction of the sliding chip.

[0014] In the present technical solution, a specific fixing scheme for the first frame-shaped portion and the second frame-shaped portion is provided, by setting a through hole in the first frame-shaped portion and a long waist hole in the second frame-shaped portion, and screws are passed between the through hole and the long waist hole, so as to fix the first frame-shaped portion and the second frame-shaped portion in the up and down directions, and along the sliding direction of the sliding chip, the first frame-shaped portion and the screws can slide in the long waist hole to realize the relative sliding of the upper chip portion and the lower chip portion of the sliding chip.

[0015] Preferably, two injection holes are further provided on the surface of the upper chip portion of the slip chip, and the range of the first through portion provided on the upper surface of the first frame-shaped portion also covers the two injection holes.

[0016] In this technical solution, by expanding the setting range of the first through-portion, the first through-portion is used not only for light passing through the observation area of ​​the SlipChip to pass through, but also for two injection holes of the SlipChip to extend, so as to facilitate the injection operation on the SlipChip.

[0017] Preferably, at least four raised blocks are provided on the upper surface of the first frame-shaped portion, and the at least four raised blocks are arranged in a two-dimensional array.

[0018] In the technical solution, a raised block is provided on the upper surface of the first frame portion to facilitate users to take and place the fixing device.

[0019] Preferably, the material of the heater is flexible, grooves for accommodating the edge of the heater are arranged on three side edges of the bottom surface of the second accommodating space, a through channel is arranged on the fourth side edge of the bottom surface of the second accommodating space, and the cable of the heater is led out at the through channel.

[0020] In this technical solution, since the material of the heater is flexible, grooves for accommodating the edges of the heater are provided on three side edges of the bottom surface of the second accommodating space, thereby accommodating the edges of the heater to prevent the heater from detaching upward from the bottom surface of the second accommodating space.

[0021] At the same time, a through channel is provided on the fourth side edge of the bottom surface of the second accommodating space, so that the cable of the heater can be led out therefrom.

[0022] Preferably, the temperature control module further comprises a base platform, on which a fixing portion is disposed, the fixing portion being used to accommodate the fixing device and to limit the freedom of movement of the fixing device except for the sliding direction of the slip chip.

[0023] In the present technical solution, a base table is provided to realize the bearing and positioning of the fixing device. The fixing portion of the base table is used to limit the other degrees of freedom of movement of the fixing device except the sliding direction of the slip chip, so as to effectively fix the fixing device and the slip chip without hindering the sliding of the slip chip.

[0024] Preferably, the fixing portion comprises: a third recessed portion formed on the upper surface of the base platform, the third recessed portion is used to accommodate the fixing device, the bottom surface of the third recessed portion is used to support the fixing device, and the third recessed portion is spaced relative to the fixing device on both sides along the sliding direction of the slip chip to form an escape space for the slip chip to slide.

[0025] In the technical solution, the third recessed portion is provided to accommodate the fixing device, which has a simple structure and has a limiting effect on the fixing device.

[0026] Preferably, elastic buckles are provided on both side walls of the third recessed portion, and the elastic buckles can be extended and retracted in a horizontal direction perpendicular to the sliding direction of the sliding chip, and when the fixing device is in the third recessed portion, the elastic buckles are compressed to clamp the fixing device.

[0027] In the present technical solution, the fixing device is clamped by providing an elastic buckle, which is more reliable and convenient for loading and unloading the fixing device.

[0028] Preferably, the base platform further comprises two semicircular notches formed on the upper surface of the base platform, the two semicircular notches are respectively arranged on both sides of the fixing device along the sliding direction of the sliding chip, and the semicircular notches extend to the side wall of the third recessed portion.

[0029] In the technical solution, two semicircular notches are provided to facilitate removal of the fixing device from the base platform.

[0030] Preferably, the base platform further comprises a power supply channel, and the power supply channel is used for allowing a cable of the heater to be led out from the third recessed portion.

[0031] Preferably, the main body of the heater is an ITO film.

[0032] In the present technical solution, the main body of the heater is set to an ITO film, which has high transparency, and can improve the detection accuracy when using the temperature control module for detection.

[0033] The positive and progressive effects of the utility model are: by providing a fixing device, the slip chip is accommodated by clamping, and reliable connection and positioning of the slip chip is achieved, and a transparent heater is further provided on the lower surface of the second frame-shaped portion so as to be clamped by the fixing device together with the slip chip, so as to provide a reliable fixing solution for a transparent heater whose material is softer than an opaque heater. When the heater is transparent, a first through portion and a second through portion are respectively provided on the first frame-shaped portion and the second frame-shaped portion, so that light can penetrate the second frame-shaped portion, the transparent heater, the observation area of ​​the slip chip, and the first frame-shaped portion from bottom to top, so that it is possible to observe the condition of the slip chip by visible light observation means such as a microscope, thereby improving the detection accuracy when the slip chip is used for detection. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] Figure 1 It is a partial exploded schematic diagram of a temperature control module of a preferred embodiment of the utility model.

[0035] Figure 2 It is a partial side view schematic diagram of a temperature control module of a preferred embodiment of the utility model.

[0036] Figure 3 It is a side view schematic diagram of the first frame portion of a preferred embodiment of the utility model.

[0037] Figure 4 It is a side view schematic diagram of the second frame portion of a preferred embodiment of the utility model.

[0038] Figure 5 The figure is a three-dimensional structural schematic diagram of a temperature control module according to a preferred embodiment of the present invention.

[0039] Description of reference numerals:

[0040] Fixture 001

[0041] The first frame portion 11

[0042] The first storage space 110

[0043] The first penetration portion 111

[0044] Through hole 112

[0045] Block 113

[0046] The second frame portion 12

[0047] The second storage space 120

[0048] The second penetration portion 121

[0049] Long waist hole 122

[0050] Cable 201

[0051] SlipChip 002

[0052] Upper chip part 21

[0053] Lower chip portion 22

[0054] Injection hole 203

[0055] Slide direction L

[0056] Heater 003

[0057] Base 004

[0058] Temperature detector 005

[0059] Elastic buckle 401

[0060] Semicircular notch 402

[0061] Avoidance space DETAILED DESCRIPTION

[0062] A preferred embodiment is given below, and the present invention is described more clearly and completely in conjunction with the accompanying drawings.

[0063] like Figure 1-Figure 5 As shown, this embodiment provides a temperature control module, which is used to accommodate the slip chip 002 and control the temperature of the slip chip 002. The temperature control module includes a fixing device 001, a heater 003 and a temperature detector 005. Figure 1 , Figure 2 As shown, the fixing device 001 includes a first frame-shaped portion 11 and a second frame-shaped portion 12 arranged relatively parallel from top to bottom. The surface of the first frame-shaped portion 11 facing the second frame-shaped portion 12 has a concave first accommodating space 110, and the peripheral edge of the first accommodating space 110 is used to fit with the upper chip portion 21 of the sliding chip 002; the surface of the second frame-shaped portion 12 facing the first frame-shaped portion 11 has a concave second accommodating space 120, and the peripheral edge of the second accommodating space 120 is used to fit with the lower chip portion 22 of the sliding chip 002. The heater 003 is disposed on the bottom surface of the second accommodating space 120, and is sandwiched between the lower chip portion 22 and the bottom surface of the second accommodating space 120. The heater 003 is transparent. Figure 3 and Figure 4 As shown, corresponding to the observation area of ​​the sliding chip 002, a first through portion 111 penetrating downward to the bottom surface of the first accommodating space 110 is provided on the upper surface of the first frame-shaped portion 11, and a second through portion 121 penetrating upward to the bottom surface of the second accommodating space 120 is provided on the lower surface of the second frame-shaped portion 12.

[0064] By providing the fixing device 001, the slip chip 002 is accommodated by clamping, and reliable connection and positioning of the slip chip 002 is achieved. Further, the transparent heater 003 is provided on the lower surface of the second frame portion 12, so as to be clamped by the fixing device 001 together with the slip chip 002, so as to provide a reliable fixing solution for the transparent heater 003 whose material is softer than the opaque heater 003. When the heater 003 is transparent, the first through portion 111 and the second through portion 121 are respectively provided on the first frame portion 11 and the second frame portion 12, so that light can penetrate the second frame portion 12, the transparent heater 003, the observation area of ​​the slip chip 002, and the first frame portion 11 from bottom to top, so that it is possible to observe the situation of the slip chip 002 by visible light observation means such as a microscope, thereby improving the detection accuracy when the slip chip 002 is used for detection.

[0065] Specifically in this embodiment, the observation area of ​​the SlipChip 002 is the area between the reagent addition ports.

[0066] In this embodiment, if Figure 5 As shown, the first frame-shaped portion 11 and the second frame-shaped portion 12 are detachably connected, and the first frame-shaped portion 11 and the second frame-shaped portion 12 can slide along the sliding direction of the slip chip 002. That is, the upper chip portion 21 of the slip chip 002 is disposed in the first frame-shaped portion 11, and the lower chip portion 22 is disposed in the second frame-shaped portion 12, so that the first frame-shaped portion 11 and the second frame-shaped portion 12 can slide along the sliding direction of the slip chip 002, so that the sliding of the fixing device 001 can drive the slip chip 002 to slide, so that the slip chip 002 can slide when it is fixed in the fixing device 001, and the operation requirements of the relevant experiments are met.

[0067] The sliding direction in this embodiment refers to Figure 5 The front-to-back direction refers to the sliding direction, while the horizontal direction perpendicular to the sliding direction refers to the left-to-right direction.

[0068] Specifically, if Figure 1 and Figure 2As shown, the first frame portion 11 and the second frame portion 12 in this embodiment are embedded, that is, the first frame portion 11 and the second frame portion 12 can be completely fitted, and the first frame portion 11 has six through holes 112, and the six through holes 112 are arranged in a two-dimensional array, and the six through holes 112 are threaded holes. The second frame portion 12 has six long waist holes 122 extending along the sliding direction, and the six through holes 112 and the six long waist holes 122 are arranged in a one-to-one correspondence. The first frame portion and the second frame portion are penetrated by screws through the through holes 112 and the long waist holes 122 to achieve sliding between the first frame portion 11 and the second frame portion 12 along the sliding direction of the sliding chip 002. The screw is first penetrated through the long waist hole 122 from bottom to top and then passes through the threaded hole, and the nut of the screw is located below the screw body. By setting a through hole 112 in the first frame portion 11 and a long waist hole 122 in the second frame portion 12, a screw is passed between the through hole 112 and the long waist hole 122 to fix the first frame portion 11 and the second frame portion 12 in the up and down directions, and in the sliding direction along the sliding chip 002, the first frame portion 11 and the screw can slide in the long waist hole 122 to realize the relative sliding of the upper chip portion 21 and the lower chip portion 22 of the sliding chip.

[0069] At the same time, in order to prevent the nut of the screw from protruding relative to the second frame portion 12, the long waist hole 122 on the second frame portion 12 is a countersunk hole to accommodate the nut.

[0070] Of course, in other embodiments, the number of through holes 112 and the long waist holes 122 can be other values, such as four, eight, etc., and the first frame portion 11 and the second frame portion 12 can also be detachably connected by other means, for example, matching convex strips and sliding grooves extending along the sliding direction of the sliding chip 002 are respectively provided on the first frame portion 11 and the second frame portion 12, which will not be repeated here.

[0071] In this embodiment, if Figure 1 As shown, two injection holes 203 are further provided on the surface of the upper chip portion 21 of the SlipChip 002, and the range of the first through-portion 111 provided on the upper surface of the first frame-shaped portion 11 also covers the two injection holes 203. The injection holes 203 are reagent addition ports for adding reagents to the SlipChip 002 in this embodiment, and the area between the two injection holes 203 is the observation area of ​​the SlipChip 002. By expanding the arrangement range of the first through-portion 111, the first through-portion 111 is used not only for allowing light passing through the observation area of ​​the SlipChip 002 to pass through, but also for allowing the two injection holes 203 of the SlipChip 002 to extend, so as to facilitate the injection operation of the SlipChip 002.

[0072] At the same time, if Figure 1 , Figure 2 , Figure 3 and Figure 5 As shown, in this embodiment, four raised blocks 113 are provided on the upper surface of the first frame-shaped portion 11, and the four raised blocks 113 are arranged in a two-dimensional array. By providing the raised blocks 113 on the upper surface of the first frame-shaped portion 11, it is convenient for the user to take and place the fixture 001, and it is avoided that bacteria in the SlipChip 002 are contaminated when taking and placing the fixture 001.

[0073] Of course, the role of the raised blocks 113 is to facilitate the user to take and place the fixing device 001. Therefore, the number of the raised blocks 113 can also be 5, 6 or other numbers, and the symmetrical arrangement of the raised blocks 113 can make the connection between the fixing device 001 and the raised blocks 113 more evenly stressed when taking and placing the fixing device 001, and the fixing device 001 is also more stable.

[0074] In this embodiment, if Figure 1 , Figure 2 and Figure 5 As shown, the material of the heater 003 is flexible, and the heater 003 is disposed on the bottom surface of the second accommodation space 120, wherein the three sides of the edge of the heater 003 are just caught by the groove 120a of the second accommodation space. Figure 2 and Figure 4 As shown, the grooves 120a are provided at the front side, the rear side and the left side of the bottom surface of the second accommodation space 120. The grooves 120a are provided to accommodate the heater 003 so as to prevent it from being displaced in the horizontal direction and from being upwardly separated from the second accommodation space when it is not pressed by the sliding chip 002. The cable 201 of the heater 003 is on the fourth side surface (i.e., Figure 4 The heater 003 is led out from the through channel 120b on the right side of the bottom surface of the second accommodation space 120, and the temperature sensor 005 is also integrated on this side for better monitoring of the heating situation. More preferably, in this embodiment, the through channel 120b is larger than the width of the heater 003, so that the heater 003 can be installed horizontally to the bottom surface of the second accommodation space 120 through the through channel 120b.

[0075] That is, the area of ​​the heater 003 is larger than the area of ​​the slip chip 002, and the lower chip portion 22 of the slip chip 002 can fully contact the heater. Since the material of the heater 003 is flexible, the heater 003 is fixed in the second accommodation space below, and the lower chip surface is completely and closely in contact with the heater. In addition, since the heater 003 is subjected to a fixed force on one side in the vertical direction, the material is not folded or squeezed, so that it can maintain good conductivity to achieve the heating function.

[0076] In this embodiment, if Figure 5As shown, the temperature control module further includes a base stage, on which a fixing portion is provided, the fixing portion being used to accommodate the fixing device 001 and to limit the freedom of movement of the fixing device 001 except for the sliding direction of the slip chip 002. The base stage is provided to achieve the support and positioning of the fixing device 001. The fixing portion of the base stage is used to limit the freedom of movement of the fixing device 001 except for the sliding direction of the slip chip 002, so as to effectively fix the fixing device 001 and the slip chip 002 without hindering the sliding of the slip chip 002.

[0077] Specifically, if Figure 5 As shown, the fixing portion includes a third recessed portion formed on the upper surface of the base platform, the third recessed portion is used to accommodate the fixing device 001, the bottom surface of the third recessed portion is used to carry the fixing device 001, and the third recessed portion is spaced relative to the fixing device 001 on both sides along the sliding direction of the slip chip 002 to form an escape space for the sliding chip 002 to slide. In other words, the third recessed portion has a bottom surface and two side walls, the bottom surface of the third recessed portion is used to carry the fixing device 001, the two side walls are spaced and extend along the sliding direction of the slip chip 002, and an escape space for the sliding chip 002 to slide is formed in the middle. By providing the third recessed portion to accommodate the fixing device 001, the structure is simple, and the fixing device 001 has a limiting effect.

[0078] In this embodiment, if Figure 5 As shown, four elastic buckles 401 are provided on both side walls of the third recessed portion, and the elastic buckles 401 can be extended and retracted in a horizontal direction perpendicular to the sliding direction of the slip chip 002. When the fixing device 001 is in the third recessed portion, the elastic buckles 401 are compressed to clamp the fixing device 001. The clamping of the fixing device 001 by providing the elastic buckles 401 is more reliable, and the installation and removal of the fixing device 001 are convenient. In the process of the fixing device 001 driving the slip chip 002 to slide, the height of the fixing device 001 and the slip chip 002 remains unchanged, and the fixing device 001 is always in contact with the bottom surface of the third recessed portion.

[0079] At the same time, if Figure 5 As shown, the base stage further includes two semicircular notches 402 formed on the upper surface of the base stage, the two semicircular notches 402 are symmetrically arranged on both sides of the fixture 001 along the sliding direction of the slip chip 002, and the semicircular notches 402 extend to the side wall of the third recessed portion. In other words, the edge of the fixture 001 can be touched through the two semicircular notches 402, so that the fixture 001 can be taken out from the base stage.

[0080] Of course, in other embodiments, rectangular notches, trapezoidal notches, etc. may be provided to facilitate the removal of the fixing device 001. In more embodiments, pull rings may be provided on the upper surface of the fixing device 001 to facilitate the removal of the fixing device 001, which will not be elaborated here.

[0081] In this embodiment, the base station also includes a power supply channel. After the cable 201 of the heater 003 is led out from the second recessed portion to the upper surface of the second frame portion 12, it is led out to the outside through the power supply channel to connect with the controller.

[0082] In this embodiment, the main body of the heater 003 is an ITO film, that is, an indium tin oxide film. By setting the main body of the heater 003 to an ITO film, it has high transparency and excellent conductivity, which can improve the detection accuracy when using the temperature control module for detection.

[0083] Meanwhile, a temperature sensor is integrated on the surface of the heater 003, and the cable 201 of the heater 003 includes a data line of the temperature sensor and a power line for controlling the heating of the main body of the heater 003. The temperature of the slip chip 002 is precisely controlled by the temperature sensor 005 and the controller. Specifically, when the temperature sensor 005 detects that the temperature is lower than the set value, the heater 003 starts to work, the main body of the heater 003 generates heat and conducts it evenly to the slip chip 002, and the heater 003 stops working when the temperature reaches the set value. During the entire temperature control process, all components below the slip chip 002 do not generate additional light and are all light-transmissive, which reduces the interference of the temperature control device on the bacterial cell imaging during the shooting process.

[0084] Although the specific implementations of the utility model are described above, those skilled in the art should understand that this is only an example, and the protection scope of the utility model is defined by the attached claims. Those skilled in the art can make various changes or modifications to these implementations without departing from the principle and essence of the utility model, but these changes and modifications fall within the protection scope of the utility model.

Claims

1. A temperature control module, used to accommodate a slip chip and control the temperature of the slip chip, characterized in that: It includes: A fixing device, the fixing device comprising a first frame-shaped portion and a second frame-shaped portion arranged relatively parallel to each other in a top-to-bottom direction, the surface of the first frame-shaped portion facing the second frame-shaped portion having a first concave accommodation space, the peripheral side edge of the first accommodation space being used to fit with the upper chip portion of the slip chip, the surface of the second frame-shaped portion facing the first frame-shaped portion having a second concave accommodation space, the peripheral side edge of the second accommodation space being used to fit with the lower chip portion of the slip chip; a heater, the heater being disposed on the bottom surface of the second receiving space and being transparent; Corresponding to the observation area of ​​the slip chip, a first through portion penetrating downward to the bottom surface of the first accommodation space is provided on the upper surface of the first frame-shaped portion, and a second through portion penetrating upward to the bottom surface of the second accommodation space is provided on the lower surface of the second frame-shaped portion.

2. The temperature control module according to claim 1, characterized in that: The first frame-shaped portion and the second frame-shaped portion are detachably connected to each other, and the first frame-shaped portion and the second frame-shaped portion can slide along a sliding direction of the slip chip.

3. The temperature control module according to claim 2, characterized in that: The first frame-shaped portion has at least four through holes, and the second frame-shaped portion has at least four long waist holes extending along the sliding direction, the through holes and the long waist holes are arranged in a one-to-one correspondence, and the first frame-shaped portion and the second frame-shaped portion are penetrated by screws in the through holes and the long waist holes, so that the first frame-shaped portion and the second frame-shaped portion can slide along the sliding direction of the sliding chip.

4. The temperature control module according to claim 1, characterized in that: Two injection holes are further provided on the surface of the upper chip portion of the sliding chip, and the range of the first through portion provided on the upper surface of the first frame-shaped portion also covers the two injection holes; And / or, at least four raised blocks are provided on the upper surface of the first frame-shaped portion, and the at least four raised blocks are arranged in a two-dimensional array.

5. The temperature control module according to claim 1, characterized in that: The material of the heater is flexible, and grooves for accommodating the edges of the heater are arranged on three sides of the bottom surface of the second accommodating space, and a through channel is arranged on the fourth side of the bottom surface of the second accommodating space, and the cable of the heater is led out at the through channel.

6. The temperature control module according to claim 1, characterized in that: The temperature control module further includes a base platform, on which a fixing portion is disposed, the fixing portion being used to accommodate the fixing device and to limit the freedom of movement of the fixing device except for the sliding direction of the slip chip.

7. The temperature control module according to claim 6, characterized in that: The fixing portion comprises: A third recessed portion is formed on the upper surface of the base platform, the third recessed portion is used to accommodate the fixing device, the bottom surface of the third recessed portion is used to support the fixing device, and the third recessed portion is spaced relative to the fixing device on both sides along the sliding direction of the slip chip to form an escape space for the slip chip to slide.

8. The temperature control module according to claim 7, characterized in that: The two side walls of the third recess are provided with elastic buckles, the elastic buckles can be extended and retracted in a horizontal direction perpendicular to the sliding direction of the sliding chip, and when the fixing device is in the third recess, the elastic buckles are compressed to clamp the fixing device; And / or, the base platform further includes two semicircular notches formed on the upper surface of the base platform, the two semicircular notches are respectively arranged on both sides of the fixing device along the sliding direction of the sliding chip, and the semicircular notches extend to the side wall of the third recessed portion.

9. The temperature control module according to claim 7, characterized in that: The base platform further includes a power supply channel, and the power supply channel is used for allowing a cable of the heater to be led out from the third recessed portion.

10. The temperature control module according to any one of claims 1 to 9, characterized in that: The main body of the heater is an ITO film.

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