Anti-blocking high performance liquid chromatograph

Abstract

The utility model belongs to the technical field of chromatographic instruments, and particularly relates to an anti-blocking high performance liquid chromatograph which comprises a chromatographic instrument host, a control panel and a liquid supply and suction assembly, and the control panel is used for controlling the solution injection amount of the liquid supply and suction assembly; the anti-combination driving part is intermittently started to control the eccentric movement disc to rotate on the inner side of the middle flow storage barrel, and after a solution is conveyed to the inner side of the middle flow storage barrel to the conveying tail pipe through the detachable liquid guide pipe to flow, floccules are scattered and mixed under the centrifugal action of the eccentric movement disc; meanwhile, when the eccentric movement disc eccentrically moves to the output port of the detachable liquid guide pipe and the output port of the middle flow storage cylinder, the compression disc keeps the contact surfaces of the flexible filling sheet and the inner cavity stripping wire with the detachable liquid guide pipe and the output port of the middle flow storage cylinder through deformation compression of the elastic connecting strip; the flocculent polymer is dispersed and gathered in the detachable liquid guide pipe and the inner diameter of the output port of the middle flow storage cylinder through the inner cavity stripping wire.

Description

Technical Field

[0001] The utility model belongs to the technical field of chromatographs, and in particular relates to an anti-clogging high performance liquid chromatograph. Background Art

[0002] Since the components in the chromatograph sample solution have different distribution coefficients in the two phases, it is easy to produce deposited flocs after long-term mixing. Although the conventional filtration method can intercept the flocs, it is easy to cause accumulation at the filtration end. Once the accumulation is aggregated in the filter pool for a long time, it is not easy to be affected by the fluidity of the solution when it passes through, which in turn affects the solution output rate and makes it impossible for the solution to pass normally. It is suitable for high performance liquid chromatography using time-controlled liquid discharge method, which is easy to produce insufficient accuracy. Utility Model Content

[0003] The utility model provides an anti-clogging high performance liquid chromatograph, which is used to solve the problems raised in the background technology.

[0004] The utility model provides the following technical solutions: an anti-blocking high-performance liquid chromatograph, comprising a chromatograph mainframe, a control panel and a liquid supply and suction assembly, wherein the control panel is used to control the amount of solution injected by the liquid supply and suction assembly, an output end of the liquid supply and suction assembly is provided with an anti-blocking intermediate transmission component and a double-cavity connection end stripping component, the anti-blocking intermediate transmission component is used for anti-blocking passing processing when the liquid supply and suction assembly outputs the solution, the anti-blocking intermediate transmission component comprises an intermediate flow storage cylinder, an anti-binding driving part, and an interval time-controlled switch, and the intermediate flow storage cylinder is fixedly connected to the outer wall of the chromatograph mainframe The outer shell of the anti-combination driving unit is fixedly connected to the outer side of the intermediate flow storage cylinder, the interval time-controlled switch is fixedly connected to the outer shell of the anti-combination driving unit, and the interval time-controlled switch is connected to the signal of the anti-combination driving unit, the double-cavity connecting end stripping assembly includes an eccentric motion disk, a compression disk and a flexible filling sheet, the eccentric motion disk is connected to the output end of the anti-combination driving unit, the bottom of the eccentric motion disk is fixedly connected to a compression disk, the bottom of the compression disk is fixedly connected to a plurality of flexible filling sheets, and the flexible filling sheet is fixedly connected to a plurality of inner cavity stripping wires.

[0005] Among them, the output end of the liquid supply and suction assembly is fixedly connected with a detachable liquid guide tube, and an elastic connecting strip is fixedly connected between the compression disk and the eccentric motion disk, and the elastic connecting strip is used to provide the displacement amount when the compression disk contacts the intermediate flow storage cylinder and the detachable liquid guide tube.

[0006] Wherein, a plurality of inner cavity stripping wires are arranged at the bottom of the flexible filling sheet, and the inner cavity stripping wires are driven to rotate by the eccentric motion disk and extend to the inner diameter of the output end of the detachable catheter or the intermediate fluid storage tube.

[0007] Wherein, a transmission gear part is arranged at one end of the eccentric motion disk, and the output end of the anti-binding driving part is meshedly connected with the transmission gear part by installing a transmission gear.

[0008] The detachable liquid guide tube is threadedly fixed to the intermediate fluid storage tube, and a sealing plug is provided between the detachable liquid guide tube and the intermediate fluid storage tube, and a transmission tail pipe is fixedly connected to the bottom of the intermediate fluid storage tube.

[0009] The beneficial effects of the utility model are as follows: the eccentric moving disk is controlled to rotate inside the intermediate flow storage tube by intermittently starting the anti-binding driving part, and after the solution is transported to the transmission tail pipe through the detachable liquid guide tube and flows inside the intermediate flow storage tube, the mixed floccules are dispersed by the centrifugal action of the eccentric moving disk, and at the same time, when the eccentric moving disk eccentrically moves to the output port of the detachable liquid guide tube and the output port of the intermediate flow storage tube, the compression disk is compressed by the deformation of the elastic connecting strip to maintain the contact surface of the flexible filling sheet and the inner cavity stripping wire with the output port of the detachable liquid guide tube and the intermediate flow storage tube, and the flocculent polymer gathered at the inner diameter of the output port of the detachable liquid guide tube and the intermediate flow storage tube is dispersed by the inner cavity stripping wire, so as to achieve the purpose of maintaining the patency of the sealing plug and the transmission tail pipe and maintain the solution output rate.

[0010] The parts not involved in the device are the same as those in the prior art or can be implemented by using the prior art. BRIEF DESCRIPTION OF THE DRAWINGS

[0011] Figure 1 It is a structural schematic diagram of the utility model;

[0012] Figure 2 It is a side view of the utility model;

[0013] Figure 3 It is a structural schematic diagram of the double-cavity connection end stripping assembly in the utility model.

[0014] In the figure: 1. Chromatograph mainframe; 2. Control panel; 3. Liquid supply and suction assembly; 31. Removable liquid guide tube; 32. Sealing plug; 4. Anti-blocking intermediate transmission member; 41. Intermediate fluid storage cylinder; 411. Transmission tail pipe; 42. Anti-binding drive unit; 43. Interval time control switch; 5. Double-cavity connecting end stripping assembly; 51. Eccentric motion disk; 511. Transmission gear unit; 52. Compression disk; 521. Elastic connecting strip; 53. Flexible filling sheet; 54. Inner cavity stripping wire. DETAILED DESCRIPTION

[0015] See also Figure 1-Figure 3The utility model provides the following technical solutions: an anti-blocking high-performance liquid chromatograph, comprising a chromatograph mainframe 1, a control panel 2 and a liquid supply and suction assembly 3, wherein the control panel 2 is used to control the amount of solution injected by the liquid supply and suction assembly 3, and an anti-blocking intermediate transmission component 4 and a double-cavity connection end stripping assembly 5 are arranged at the output end of the liquid supply and suction assembly 3, and the anti-blocking intermediate transmission component 4 is used for anti-blocking processing when the liquid supply and suction assembly 3 outputs the solution, and the anti-blocking intermediate transmission component 4 comprises an intermediate storage cylinder 41, an anti-binding driving part 42, and an interval time control switch 43, and the intermediate storage cylinder 41 is fixedly connected to the outer wall of the chromatograph mainframe 1, and the anti-blocking The outer shell of the combining drive unit 42 is fixedly connected to the outer side of the intermediate flow storage cylinder 41, the interval time-controlled switch 43 is fixedly connected to the outer shell of the anti-combination drive unit 42, and the interval time-controlled switch 43 is signal-connected to the anti-combination drive unit 42, the double-cavity connecting end stripping assembly 5 includes an eccentric motion disk 51, a compression disk 52 and a flexible filling sheet 53, the eccentric motion disk 51 is connected to the output end of the anti-combination drive unit 42, the bottom of the eccentric motion disk 51 is fixedly connected to the compression disk 52, the bottom of the compression disk 52 is fixedly connected to a plurality of flexible filling sheets 53, and the flexible filling sheet 53 is fixedly connected to a plurality of inner cavity stripping wires 54.

[0016] In the present embodiment, the chromatograph mainframe 1, the control panel 2 and the liquid supply and suction assembly 3 are all components of the existing chromatograph, and are not the improved contents of the present utility model. The improved contents of the present utility model are the anti-blocking treatment when the chromatograph transports the solution sample. Therefore, the specific use principle of the control end will not be described in detail. The control panel 2 is connected to the interval time control switch 43 by signal. After the control panel 2 set by the chromatograph mainframe 1 initiates the solution transport command to the liquid supply and suction assembly 3, the interval time control switch 43 receives the control signal of the control panel 2 and starts synchronously, that is, the intermittent drive interval length of the anti-binding drive unit 42 is set according to the liquid output of the chromatograph mainframe 1, so that the anti-binding drive unit 42 is intermittently started to control the eccentric motion disk 51 to rotate inside the intermediate storage cylinder 41, and then After the solution passes through the detachable liquid guiding tube 31 and is transported to the transmission tail pipe 411 and flows to the inner side of the intermediate flow storage tube 41, the mixed floccules are broken up by the centrifugal action of the eccentric moving disk 51. Meanwhile, when the eccentric moving disk 51 eccentrically moves to the output port of the detachable liquid guiding tube 31 and the output port of the intermediate flow storage tube 41, the compression disk 52 is compressed by the deformation of the elastic connecting strip 521 to maintain the contact surface between the flexible filling sheet 53 and the inner cavity stripping wire 54 and the output port of the detachable liquid guiding tube 31 and the intermediate flow storage tube 41. The flocculent polymer gathered at the inner diameter of the output port of the detachable liquid guiding tube 31 and the intermediate flow storage tube 41 is dispersed by the inner cavity stripping wire 54, so as to maintain the patency of the sealing plug 32 and the transmission tail pipe 41 and maintain the output rate of the solution.

[0017] The output end of the liquid supply and suction assembly 3 is fixedly connected with a detachable liquid guide tube 31, and an elastic connecting strip 521 is fixedly connected between the compression disk 52 and the eccentric motion disk 51. The elastic connecting strip 521 is used to provide the displacement when the compression disk 52 contacts the intermediate flow storage cylinder 41 and the detachable liquid guide tube 31.

[0018] In the present embodiment, since the eccentric moving disk 51 and the compression disk 52 are connected by the elastic connecting strip 521, when the eccentric moving disk 51 drives the flexible filling sheet 53 to rotate inside the intermediate flow storage tube 41, after the flexible filling sheet 53 contacts the inner wall of the intermediate flow storage tube 41, the elastic connecting strip 521 can reduce the rotation resistance of the eccentric moving disk 51 by its own deformation, and at the same time ensure the contact surface between the flexible filling sheet 53 and the inner wall of the intermediate flow storage tube 41, so as to stably disperse the flocs gathered at the outlet of the detachable liquid guide tube 31 and the transmission tail tube 411.

[0019] A plurality of inner cavity stripping wires 54 are provided at the bottom of the flexible filling sheet 53 . The inner cavity stripping wires 54 are driven to rotate by the eccentric motion disk 51 and extend to the inner diameter of the output end of the detachable liquid guide tube 31 or the intermediate fluid storage tube 41 .

[0020] In this embodiment, the inner cavity stripping wire 54 is used to increase the extension length toward the inner side of the detachable catheter tube 31 and the tube opening of the transmission tail tube 411, so that the polymer retained at the tube opening of the transmission tail tube 411 and the detachable catheter tube 31 can be stably dispersed.

[0021] A transmission gear portion 511 is disposed at one end of the eccentric motion disk 51 , and the output end of the anti-binding driving portion 42 is meshedly connected with the transmission gear portion 511 by installing a transmission gear.

[0022] In this embodiment, after the transmission gear is installed on the output end of the anti-binding driving part 42 , the intermediate accumulator 41 is driven to rotate by meshing with the transmission gear part 511 .

[0023] The detachable liquid guide tube 31 is screwed and fixed to the intermediate flow storage tube 41, and a sealing plug 32 is provided between the detachable liquid guide tube 31 and the intermediate flow storage tube 41, and a transmission tail pipe 411 is fixedly connected to the bottom of the intermediate flow storage tube 41; in this embodiment, the intermediate flow storage tube 41 can be removed by removing the connecting bolts between the detachable liquid guide tube 31 and the intermediate flow storage tube 41, so as to clean the inside of the intermediate flow storage tube 41 after use.

[0024] The working principle and use process of the utility model are as follows: after the control panel 2 sends a solution delivery command to the liquid supply and suction assembly 3, the interval time control switch 43 receives the control signal of the control panel 2 and starts synchronously, that is, the anti-combination drive unit 42 starts intermittently to control the eccentric motion disk 51 to rotate inside the intermediate storage cylinder 41, and then after the solution is delivered to the transmission tail pipe 411 through the detachable liquid guide tube 31 and flows inside the intermediate storage cylinder 41, the mixed floccules are dispersed by the centrifugal action of the eccentric motion disk 51, and at the same time, the eccentric motion disk 51 moves eccentrically to the inside of the intermediate storage cylinder 41. When the output port of the detachable liquid conduit 31 and the output port of the intermediate fluid storage tube 41 are positioned, the compression disk 52 is compressed by the deformation of the elastic connecting strip 521 to maintain the contact surface between the flexible filling sheet 53 and the inner cavity stripping wire 54 and the output port of the detachable liquid conduit 31 and the intermediate fluid storage tube 41, and the flocculent polymer gathered at the inner diameter of the output port of the detachable liquid conduit 31 and the intermediate fluid storage tube 41 is dispersed by the inner cavity stripping wire 54, so as to achieve the purpose of maintaining the patency of the sealing plug 32 and the transmission tail tube 41, and maintaining the solution output rate.

Claims

1. A high performance liquid chromatograph with anti-clogging function, comprising a chromatograph mainframe (1), a control panel (2) and a liquid supply and suction assembly (3), wherein the control panel (2) is used to control the amount of solution injected by the liquid supply and suction assembly (3), and characterized in that: The output end of the liquid supply and suction assembly (3) is provided with an anti-blocking intermediate transmission component (4) and a double-cavity connection end stripping component (5). The anti-blocking intermediate transmission component (4) is used for anti-blocking processing when the liquid supply and suction assembly (3) outputs the solution. The anti-blocking intermediate transmission component (4) includes an intermediate flow storage cylinder (41), an anti-binding driving part (42), and an interval time control switch (43). The intermediate flow storage cylinder (41) is fixedly connected to the outer wall of the chromatograph mainframe (1), the outer shell of the anti-binding driving part (42) is fixedly connected to the outer side of the intermediate flow storage cylinder (41), and the interval time control switch (43) is fixedly connected to the outer wall of the chromatograph mainframe (1). The invention relates to an outer shell of the anti-combination driving part (42), and the interval time-controlled switch (43) is connected to the anti-combination driving part (42) by signal. The double-cavity connection end stripping component (5) comprises an eccentric motion disk (51), a compression disk (52) and a flexible filling sheet (53). The eccentric motion disk (51) is connected to the output end of the anti-combination driving part (42). The bottom of the eccentric motion disk (51) is fixedly connected to the compression disk (52). The bottom of the compression disk (52) is fixedly connected to a plurality of flexible filling sheets (53). The flexible filling sheet (53) is fixedly connected to a plurality of inner cavity stripping wires (54).

2. The anti-clogging high performance liquid chromatograph according to claim 1, characterized in that: The output end of the liquid supply and suction assembly (3) is fixedly connected to a detachable liquid guide tube (31), and an elastic connecting strip (521) is fixedly connected between the compression disk (52) and the eccentric motion disk (51), and the elastic connecting strip (521) is used to provide a displacement amount when the compression disk (52) contacts the intermediate fluid storage cylinder (41) and the detachable liquid guide tube (31).

3. The anti-clogging high performance liquid chromatograph according to claim 2, characterized in that: The bottom of the flexible filling sheet (53) is provided with a plurality of inner cavity stripping wires (54), and the inner cavity stripping wires (54) are driven to rotate by the eccentric motion disk (51) and extend to the inner diameter of the output end of the detachable liquid guide tube (31) or the intermediate fluid storage cylinder (41).

4. The anti-clogging high performance liquid chromatograph according to claim 3, characterized in that: A transmission gear portion (511) is provided at one end of the eccentric motion disk (51), and the output end of the anti-binding driving portion (42) is meshedly connected with the transmission gear portion (511) by installing a transmission gear.

5. The anti-clogging high performance liquid chromatograph according to claim 2, characterized in that: The detachable liquid guide tube (31) is threadedly fixed to the intermediate fluid storage tube (41), and a sealing plug (32) is provided between the detachable liquid guide tube (31) and the intermediate fluid storage tube (41), and a transmission tail pipe (411) is fixedly connected to the bottom of the intermediate fluid storage tube (41).

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