Automatic cell smear machine

Abstract

The utility model relates to the technical field of smear machines, and specifically to an automatic cell smear machine, comprising a machine body and a machine cover, wherein the machine cover is covered on the upper end of the machine body; a centrifugal chamber is opened in the machine body, a centrifugal tray is installed in the centrifugal chamber, a glass slide and a chamber are arranged on the centrifugal tray, a plurality of mounting grooves are opened on the periphery of the centrifugal tray, a cabin is arranged in the mounting grooves, a plurality of contraction grooves are opened on the inner wall of the cabin, a slider is arranged in the contraction groove, a positioning ball is rotatably connected to the inner side of the slider, and the positioning ball extends out of the contraction groove; the utility model is conducive to preventing the outer wall of the sample tank and the inner wall of the cabin from generating high-frequency collision due to the gap, avoiding the occurrence of abnormal noise, and is also conducive to preventing the sample tank from being damaged due to collision, and is conducive to quickly shaking and evenly shaking the cells in the sample tank, thereby effectively shortening the processing time and ensuring the working efficiency of the smear machine.

Description

Technical Field

[0001] The utility model relates to the technical field of smear machines, in particular to an automatic cell smear machine. Background Art

[0002] The centrifuge is one of the most commonly used instruments in the laboratory. It achieves centrifugal separation by accelerating the rotation of samples. In the field of life sciences, centrifuges are often used for the separation, purification and concentration of cells, viruses, DNA and proteins. The smear centrifuge is a special centrifuge that adds a smear rotor to the ordinary centrifuge for thin layer centrifugal separation.

[0003] In the prior art, when the smear machine is working, it uses the smear as a carrier to suspend the cells or tissues to be detected on the smear, separates various cell types through centrifugal force, and observes and studies them on the smear. In this process, the sample can containing the cells is placed in the cabin on the centrifugal tray. Although the cabin can limit the sample can, there will inevitably be a gap between the inner wall of the cabin and the outer wall of the sample can. When the smear machine drives the centrifugal tray, the cabin and the sample can for centrifugal work, the sample can will collide with the inner wall of the cabin due to the gap, which will not only produce abnormal noise, but also the high-frequency impact will easily damage the sample can. In addition, there is a lack of shaking measures before the cells are centrifuged for smearing. If the cells in the sample can are not uniform before centrifuging for smearing, it will lead to a long processing time and low work efficiency. Utility Model Content

[0004] In view of the deficiencies of the prior art, the utility model provides an automatic cell smear machine to solve the problems of collision caused by the gap between the inner wall of the cabin and the outer wall of the sample tank, and the lack of pre-shaking of the cells.

[0005] To achieve the above objectives, the utility model is implemented through the following technical solutions: an automatic cell smear machine, comprising a machine body and a machine cover, wherein the machine cover is covered on the upper end of the machine body;

[0006] The body is provided with a centrifugal chamber, a centrifugal tray is installed in the centrifugal chamber, a glass slide and a chamber are arranged on the centrifugal tray, a plurality of mounting grooves are arranged on the periphery of the centrifugal tray, a cabin is arranged in each of the mounting grooves, a plurality of contraction grooves are arranged on the inner wall of the cabin, a slider is arranged in each of the contraction grooves, a positioning ball is rotatably connected to the inner side of the slider, the positioning ball extends out of the contraction groove, and a return spring is connected between the outer side of the slider and the inner wall of the contraction groove;

[0007] A plurality of movable grooves are opened in the centrifugal tray, and the plurality of movable grooves are alternately distributed with a plurality of cabins. Support rods are fixed at both ends of the outer side of the cabin. The support rods slide through the centrifugal tray into adjacent movable grooves, and pressure plates are fixed at the ends of the support rods. At least two return springs are connected between the pressure plates and the inner walls of the movable grooves, and a shaking drive assembly is provided in the movable grooves.

[0008] Preferably, two telescopic rods are connected between the outer side of the sliding block and the inner wall of the shrinkage groove.

[0009] Preferably, the shaking drive components include a motor, a rotating shaft, an impact ball and a semicircular protrusion, the motor is fixed in the movable groove, one end of the rotating shaft is connected to the motor power end, and the other end of the rotating shaft is rotatably connected to the inner wall of the movable groove.

[0010] Preferably, two impact balls are provided, and the impact balls are fixed on both sides of the rotating shaft, and the semicircular protrusions are fixed on the sides of adjacent pressure plates, and the impact balls correspond to the semicircular protrusions.

[0011] Preferably, an electric telescopic shaft is fixed in each of the mounting grooves, a power end of the electric telescopic shaft is connected to a limit plug block, and a slot block is fixed on an outer wall of the cabin.

[0012] Preferably, the limiting plug block is in a truncated cone shape, and the limiting plug block is interference fit with the notch of the slot block.

[0013] The utility model provides an automatic cell smear machine, which has the following beneficial effects:

[0014] 1. By inserting the sample can into the cabin, the elastic force of the return spring will drive multiple positioning balls to clamp the outer wall of the sample can. When the smear machine drives the sample can to perform centrifugal smearing, the elasticity of the return spring will buffer the sample can, thereby preventing the outer wall of the sample can and the inner wall of the cabin from generating high-frequency collision due to the gap, avoiding the occurrence of abnormal noise, and preventing the sample can from being damaged due to collision;

[0015] 2. The shaking drive assembly drives the pressure plate to compress or stretch the reset spring, and then the resilience of the reset spring drives the cabin and the sample tank to shake back and forth, which is conducive to quickly shaking the cells in the sample tank, thereby effectively shortening the processing time and ensuring the working efficiency of the smear machine. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0017] Figure 2 This is a schematic diagram of the internal planar structure of the machine body of the utility model when viewed from above;

[0018] Figure 3 This is a schematic diagram of the internal planar structure of the centrifugal tray of the utility model when viewed from above;

[0019] Figure 4 This is a schematic diagram of the internal plan structure of the cabin of the utility model when viewed from above;

[0020] Figure 5 It is a schematic diagram of the partially enlarged structure of A of the utility model.

[0021] Figure 1-5 In the figure: body 1, centrifugal chamber 2, centrifugal tray 3, mounting slot 4, cabin 5, storage slot 6, slider 7, positioning ball 8, return spring 9, telescopic rod 10, movable slot 11, pressure plate 12, return spring 13, motor 14, rotating shaft 15, impact ball 16, semicircular protrusion 17, electric telescopic shaft 18, limit plug 19, slot block 20, machine cover 21, support rod 22. DETAILED DESCRIPTION

[0022] The technical solutions in the embodiments of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the utility model.

[0023] See also Figure 1-5 The utility model provides a technical solution: an automatic cell smear machine, comprising a body 1 and a cover 21, the cover 21 covers the upper end of the body 1, a centrifugal chamber 2 is opened in the body 1, a centrifugal tray 3 is installed in the centrifugal chamber 2, and a slide and a chamber are arranged on the centrifugal tray 3, a plurality of mounting grooves 4 are opened on the periphery of the centrifugal tray 3, a cabin 5 is arranged in each of the mounting grooves 4, a plurality of contraction grooves 6 are opened on the inner wall of the cabin 5, a slider 7 is arranged in each of the contraction grooves 6, a positioning ball 8 is rotatably connected to the inner side of the slider 7, the positioning ball 8 extends out of the contraction groove 6, and a return spring 9 is connected between the outer side of the slider 7 and the inner wall of the contraction groove 6.

[0024] By inserting the sample can into the cabin 5, the sample can will push the slider 7 into the contraction groove 6 along the arc surface of the positioning ball 8. During this process, since the positioning ball 8 will rotate on the slider 7, it is beneficial to ensure the smoothness of placing the sample can into the cabin 5, and the slider 7 will compress the return spring 9 until the sample can is installed in the cabin 5. Then, the elastic force of the return spring 9 will drive the slider 7 and the positioning ball 8 to reset, and then multiple positioning balls 8 will be clamped on the outer wall of the sample can. When the smear machine drives the sample can for centrifugal smearing, the sample can is buffered by the elasticity of the return spring 9, thereby preventing the outer wall of the sample can and the inner wall of the cabin 5 from generating high-frequency collision due to the gap, avoiding the occurrence of abnormal noise, and also helping to prevent the sample can from being damaged by collision.

[0025] In this embodiment, two telescopic rods 10 are connected between the outer side of the sliding block 7 and the inner wall of the shrinkage groove 6 .

[0026] When the slider 7 moves in the contraction groove, the slider 7 will compress or stretch the telescopic rod 10 at the same time, which is conducive to ensuring the stability of the slider 7 when moving, thereby ensuring the stability of the positioning ball 8 when clamping the sample can.

[0027] In this embodiment, a plurality of movable grooves 11 are opened in the centrifugal tray 3, and the plurality of movable grooves 11 are alternately distributed with the plurality of cabins 5. Support rods 22 are fixed at both ends of the outer side of the cabin 5. The support rods 22 slide through the centrifugal tray 3 and penetrate into the adjacent movable grooves 11. Pressure plates 12 are fixed at the ends of the support rods 22. At least two return springs 13 are connected between the pressure plates 12 and the inner walls of the movable grooves 11. A shaking drive assembly is provided in the movable grooves 11. The shaking drive components include a motor 14, a rotating shaft 15, an impact ball 16 and a semicircular protrusion 17. The motor 14 is fixed in the movable groove 11. One end of the rotating shaft 15 is connected to the power end of the motor 14, and the other end of the rotating shaft 15 is rotatably connected to the inner wall of the movable groove 11. Two impact balls 16 are provided, and the impact balls 16 are fixed on both sides of the rotating shaft 15. The semicircular protrusions 17 are fixed on the sides of the adjacent pressure plates 12, and the impact balls 16 correspond to the semicircular protrusions 17.

[0028] When the sample tank is installed, in order to improve the uniformity of the cells in the sample tank, the motor 14 is used to drive the rotating shaft 15 and the impact ball 16 to rotate, and the impact ball 16 will hit the semicircular protrusion 17, and then the semicircular protrusion 17 will push the pressure plate 12, the support rod 22, the cabin 5 and the sample tank to move together, and at the same time the pressure plate 12 will compress or stretch the reset spring 13, and then the resilience of the reset spring 13 will drive the cabin 5 and the sample tank to shake back and forth, which is beneficial to quickly shake the cells in the sample tank evenly, thereby effectively shortening the processing time and ensuring the working efficiency of the smear machine.

[0029] In this embodiment, an electric telescopic shaft 18 is fixed in the installation groove 4, and the power end of the electric telescopic shaft 18 is connected to a limit plug block 19. The outer wall of the cabin 5 is fixed with a slot block 20. The limit plug block 19 is truncated cone-shaped, and the limit plug block 19 and the slot block 20 have an interference fit.

[0030] After the cells in the sample tank are shaken evenly, the electric telescopic shaft 18 is extended to drive the limit block 19 to be inserted into the notch in the slot block 20. Since the limit block 19 is truncated cone-shaped and the limit block 19 and the notch of the slot block 20 have an interference fit, the limit block 19 can be accurately and firmly inserted into the notch of the slot block 20, which is conducive to achieving the effect of fixing the cabin 5. When the smear machine drives the sample tank for centrifugal smearing, the cabin 5 and the sample tank are prevented from continuing to shake, effectively ensuring the normal operation of the sample tank during centrifugal smearing.

[0031] Working principle:

[0032] By inserting the sample tank into the cabin 5, the sample tank will push the slider 7 into the contraction groove 6 along the arc surface of the positioning ball 8. During this process, the slider 7 will compress the return spring 9 until the sample tank is installed in the cabin 5. Then, the elastic force of the return spring 9 will drive the slider 7 and the positioning ball 8 to reset. Then, multiple positioning balls 8 will be clamped on the outer wall of the sample tank. Then, the motor 14 will drive the rotating shaft 15 and the impact ball 16 to rotate. The impact ball 16 will hit the semicircular protrusion 17. Then, the semicircular protrusion 17 will push the pressure plate 12, the support rod 22, the cabin 5 and the sample tank together. Move, and at the same time, the pressure plate 12 will compress or stretch the reset spring 13, and then the cabin 5 and the sample tank are driven to shake back and forth through the resilience of the reset spring 13, so as to complete the shaking of the cells in the sample tank. Since a glass slide is installed on the centrifugal tray 3, a chamber is also provided. The chamber and the glass slide are used as the prior art. Under the premise that the chamber and the glass slide are tightly fitted, after the sample is filled in the chamber, centrifugation is performed to achieve uniform spraying of the sample on the glass slide, and the preparation of the slide is achieved (the specific centrifugation work flow of the automatic smear machine is relatively mature in the prior art, so this case will not be described in detail).

[0033] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An automatic cell smear machine, comprising a machine body (1) and a machine cover (21), wherein the machine cover (21) covers the upper end of the machine body (1), characterized in that: The body (1) is provided with a centrifugal chamber (2), a centrifugal tray (3) is installed in the centrifugal chamber (2), a glass slide and a chamber are provided on the centrifugal tray (3), a plurality of mounting grooves (4) are provided on the periphery of the centrifugal tray (3), a cabin (5) is provided in each of the mounting grooves (4), a plurality of contraction grooves (6) are provided on the inner wall of the cabin (5), a slider (7) is provided in each of the contraction grooves (6), a positioning ball (8) is rotatably connected to the inner side of the slider (7), the positioning ball (8) extends out of the contraction groove (6), and a return spring (9) is connected between the outer side of the slider (7) and the inner wall of the contraction groove (6); A plurality of movable grooves (11) are provided in the centrifugal tray (3), and the plurality of movable grooves (11) are alternately distributed with the plurality of cabins (5). Support rods (22) are fixed at both ends of the outer side of the cabin (5), and the support rods (22) are slidably penetrated into adjacent movable grooves (11) through the centrifugal tray (3), and pressure plates (12) are fixed at the ends of the support rods (22). At least two return springs (13) are connected between the pressure plates (12) and the inner walls of the movable grooves (11), and a shaking drive component is provided in the movable grooves (11).

2. The automatic cell smear machine according to claim 1, characterized in that: Two telescopic rods (10) are connected between the outer side of the sliding block (7) and the inner wall of the contraction groove (6).

3. The automatic cell smear machine according to claim 1, characterized in that: The shaking driving components all include a motor (14), a rotating shaft (15), an impact ball (16) and a semicircular protrusion (17); the motor (14) is fixed in the movable groove (11); one end of the rotating shaft (15) is connected to the power end of the motor (14); and the other end of the rotating shaft (15) is rotatably connected to the inner wall of the movable groove (11).

4. The automatic cell smear machine according to claim 3, characterized in that: The impact balls (16) are provided with two each and are fixed on both sides of the rotating shaft (15). The semicircular protrusions (17) are fixed on the side surfaces of the adjacent pressing plates (12), and the impact balls (16) correspond to the semicircular protrusions (17).

5. The automatic cell smear machine according to claim 1, characterized in that: An electric telescopic shaft (18) is fixed in each of the installation grooves (4), a power end of the electric telescopic shaft (18) is connected to a limit insertion block (19), and a slot block (20) is fixed to the outer wall of the cabin (5).

6. The automatic cell smear machine according to claim 5, characterized in that: The limiting plug block (19) is in a truncated cone shape, and the limiting plug block (19) is interference-fitted with the notch of the slot block (20).

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