Sealing device, control mechanism, conveying system and intervention system

Abstract

The utility model relates to the technical field of medical instruments, and discloses a sealing device, a control mechanism, a conveying system and an intervention system. The sealing device comprises a flow blocking piece and a sealing piece. The flow choking piece comprises a flow choking part and a first base part; the flow choking part is arranged at the first end of the first base part, comprises a one-way flow choking structure and is used for preventing liquid in the first direction from flowing. The sealing piece comprises a bottom and a connecting part, the bottom is provided with a through hole, the connecting part is matched with the first base part, and the sealing piece is connected to the second end of the first base part. When the sealing piece is connected to the first base part, a first space is formed between the bottom part and the one-way flow choking structure; in the second direction, the through hole is used for the first guide pipe to penetrate into the first space and is sealed by the first guide pipe; the one-way flow choking structure is used for enabling the first guide pipe to penetrate out of the first space, and the one-way flow choking structure is attached to the first guide pipe. The first direction is the direction from the flow blocking piece to the sealing piece, and the second direction is the direction from the sealing piece to the flow blocking piece. The sealing device can improve the sealing performance of the control mechanism.

Description

Technical Field

[0001] The present application relates to the technical field of medical devices, and further to a sealing device, a control mechanism, a delivery system and an interventional system. Background Art

[0002] Interventional diagnosis or treatment can achieve better diagnostic or therapeutic effects through smaller wounds and is more conducive to postoperative recovery, so it has been used more and more widely. In interventional technology, the operator can use the delivery system to deliver materials, medical devices, or drugs and other substances into the body under the guidance of medical imaging equipment (for example, angiography, fluoroscopy, computed tomography (CT), magnetic resonance imaging (MR), ultrasound, etc.) to perform minimally invasive diagnosis or treatment of diseases. The sealing performance of the delivery system affects the diagnostic or therapeutic effect and needs to be further improved. Utility Model Content

[0003] In view of this, the present application provides a sealing device, a control mechanism, a delivery system and an intervention system to improve the sealing performance of the delivery system.

[0004] In a first aspect, a sealing device is provided, comprising a flow blocker and a sealing member. The flow blocker comprises a flow blocker and a first base; the flow blocker is arranged at the first end of the first base and comprises a one-way flow blocker structure for preventing the flow of liquid in a first direction. The sealing member comprises a bottom and a connecting member, the bottom having a through hole, the connecting member matches the first base, and the sealing member is connected to the second end of the first base. When the sealing member is connected to the first base, a first space is formed between the bottom and the one-way flow blocker structure; and in the second direction, the through hole is used for the first conduit to penetrate into the first space, the one-way flow blocker structure is used for the first conduit to penetrate out of the first space, and when the first conduit passes through the first space, the through hole is sealed by the first conduit, and the one-way flow blocker structure is attached to the first conduit. The first direction is the direction from the flow blocker to the sealing member, and the second direction is the direction from the sealing member to the flow blocker.

[0005] The above sealing device can achieve a two-way sealing effect, and the sealing performance of the control mechanism is significantly improved; it can prevent air from entering the blood vessels through the control mechanism, reducing the risk of air embolism, and prevent blood from flowing back and leaking out, reducing damage to the organism and reducing pollution to the surgical environment.

[0006] Optionally, the one-way flow-blocking structure includes a plurality of membrane petals, and a flow-blocking space is formed between adjacent membrane petals, which is used to block the liquid flowing in the first direction in the flow-blocking space. In this way, a plurality of membrane-like intervals can be formed inside the flow-blocking portion, dividing the space in the first direction into a plurality of flow-blocking spaces. When the flow-blocking space is filled with liquid and subjected to the liquid pressure in the first direction, the plurality of membrane-like intervals gather together to retain the liquid in the flow-blocking portion. The one-way flow-blocking structure is simple in structure and low in cost in implementation, and has a good flow-blocking effect.

[0007] Optionally, the flow blocking portion includes a tube body, which is hollow inside and is arranged at the first end of the first base; a plurality of membrane petals are arranged inside the tube body, and one side edge of the plurality of membrane petals is connected to the inner wall of the tube body, and the other side edges of adjacent membrane petals are connected to form a plurality of connecting edges; the distance between the plurality of connecting edges gradually decreases along the second direction until they abut against each other. In this way, the size of the first space gradually decreases along the second direction, which plays a guiding role for the first conduit to be inserted, and is more conducive to the insertion of the first conduit, and when the first conduit is inserted, the connecting edge can better fit the first conduit, further improving the sealing performance.

[0008] Optionally, the connecting edge is an arc-shaped edge. In this way, the blocking space can have an arc-shaped inner wall, and blood can flow into the blocking space along the arc-shaped inner wall, which plays a blood diversion and buffering effect, and prevents the blood from exerting too much pressure on the blocking space, causing undesirable deformation of the blocking space and resulting in poor sealing.

[0009] Optionally, a plurality of membrane petals are centrally symmetrically distributed inside the tube body. By arranging the membrane petals in this way, each flow-blocking space is evenly distributed, the force is evenly applied, and the sealing performance is better.

[0010] Optionally, the inner contour of the second end of the first base portion matches the outer contour of the connecting portion; or, the outer contour of the second end of the first base portion matches the inner contour of the connecting portion.

[0011] Optionally, the seal also includes a second base, the connecting portion is arranged at the first end of the bottom, and the second base is arranged at the second end of the bottom. The sealing device also includes a guide member, including a guide body; the interior of the guide body is hollow and is provided with a guide structure, the outer wall of the guide body matches the second base, and the guide member is connected to the second end of the bottom of the seal. When the guide member is connected to the second base, a second space is formed between the guide structure and the bottom, and the guide structure has a guide hole for the first catheter to pass through the second space, and a through hole for the first catheter to pass through the second space, and the guide hole and the center of the through hole are coaxial. Through the provision of the guide member, the first catheter can pass through the sealing device more smoothly, improve the convenience of operation of the conveying system, and reduce the damage that may be caused to the seal or the control mechanism by the misaligned operation.

[0012] Optionally, the guide structure comprises a dome structure protruding toward the second direction, and the guide hole is arranged at the center of the dome structure. The dome structure has the ability to disperse force, has better stability, and thus has a longer service life.

[0013] Optionally, the guide hole is a cross hole. The second through hole 300 is arranged at the center of the dome structure 31. The second through hole 300 has many forms, such as the cross hole in the figure, and can also be arranged as an ordinary round hole.

[0014] Optionally, the guide member further comprises at least one of the following supporting structures: a first supporting structure, comprising a plurality of first supporting members, supported on a first end face of the guide structure, the first end face being the end face of the guide structure facing the second direction; a second supporting structure, comprising a plurality of second supporting members, supported on a second end face of the guide structure, the second end face being the end face of the guide structure facing the first direction. By providing at least one of the above supporting structures, the strength of the guide member can be enhanced, making it less likely to deform under the influence of external forces, thereby extending the service life of the sealing device.

[0015] Optionally, the guide member includes a first support structure and a second support structure, and a plurality of first support members are centrally symmetrically distributed around the guide hole; and a plurality of second support members are centrally symmetrically distributed around the guide hole.

[0016] Optionally, the material of the sealing device includes an elastic biocompatible material. For example, the baffle and the seal are made of an elastic biocompatible material. In another example, the baffle, the seal and the guide are made of an elastic biocompatible material. In this way, the sealing device can be elastically deformed under the influence of external force, but has a tendency to return to its original state after the external force is removed, so as to prevent the deformation caused by the external force during use, which causes the sealing performance to decrease. In addition, the connection between the components is easier to achieve through snap-on connection, which is convenient for assembly and / or disassembly.

[0017] In a second aspect, a control mechanism is provided for controlling a second catheter; the control system comprises a housing, a base, and any one of the sealing devices of the first aspect. The housing has a through hole inside for accommodating the proximal end of the second catheter. The base is disposed at the proximal end of the housing and has a first opening and a second opening; the first opening is connected to the through hole, and the second opening is used for the first catheter to penetrate. The sealing device is disposed between the first opening and the second opening, and is used to seal the penetration path of the first catheter when the first catheter penetrates the through hole through the second opening and the first opening.

[0018] In a third aspect, a delivery system is provided, comprising: a second catheter, and the control mechanism of the second aspect, for controlling the second catheter.

[0019] Optionally, a wire pulling channel is provided in the second catheter, and a support structure and a wire pulling fixing structure are provided at the distal end of the second catheter. The delivery system also includes a wire pulling line, the wire pulling line passes through the wire pulling channel, the distal end is connected to the wire pulling fixing structure, and the proximal end is connected to the control mechanism, and the control mechanism controls the bending state of the distal end of the second catheter through the wire pulling line. The support structure includes a first side and a second side, and the distance between the wire pulling channel and the first side is smaller than the distance between the wire pulling channel and the second side.

[0020] Optionally, the support structure includes multiple support segments, the multiple support segments are connected on a first side and have a non-through first hollow structure between two ends of the first side, and the multiple support segments have a through second hollow structure between two ends of the second side.

[0021] In a fourth aspect, an intervention system is provided, comprising an intervention substance, and any one of the delivery systems in the third aspect, for delivering the intervention substance. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] The following is a brief introduction to the drawings used in describing the embodiments of the present application:

[0023] Figure 1 A schematic diagram of the structure of an intervention system provided in an embodiment of the present application;

[0024] Figure 2-Figure 6 A schematic diagram of an implantation process of a valve clip provided in an embodiment of the present application;

[0025] Figure 7 A plan view of a control mechanism provided in an embodiment of the present application;

[0026] Figure 8 for Figure 7 A cross-sectional view of the control mechanism shown along the AA direction;

[0027] Fig. 9 A schematic structural diagram of a sealing device provided in an embodiment of the present application;

[0028] Fig.10 A schematic diagram of a three-dimensional structure of a flow-blocking member provided in an embodiment of the present application;

[0029] Fig.11 An axial cross-sectional view of a flow-blocking element provided in an embodiment of the present application;

[0030] Fig.12 A schematic diagram of a three-dimensional structure of a sealing member provided in an embodiment of the present application;

[0031] Fig.13 An axial cross-sectional view of a seal provided in an embodiment of the present application;

[0032] Fig.14A schematic structural diagram of another sealing device provided in an embodiment of the present application;

[0033] Fig.15 A schematic diagram of a three-dimensional structure of a guide member provided in an embodiment of the present application;

[0034] Fig.16 An axial cross-sectional view of a guide member provided in an embodiment of the present application;

[0035] Fig.17 An exploded diagram of a control mechanism provided in an embodiment of the present application;

[0036] Fig.18 A schematic diagram of the structure of a steering assembly provided in an embodiment of the present application;

[0037] Fig.19 A schematic structural diagram of the distal end of a catheter provided in an embodiment of the present application. DETAILED DESCRIPTION

[0038] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the specific implementation methods of the present application will be described below with reference to the accompanying drawings. The accompanying drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other accompanying drawings and other embodiments can be obtained based on these accompanying drawings without creative work. Adjustments and improvements made without departing from the concept of the present application are all within the scope of protection of the present application.

[0039] In order to simplify the drawings, the drawings in the embodiments of the present application only schematically show the parts related to the embodiments of the application, and they do not represent the actual structure of the product. In addition, in order to simplify the drawings and facilitate understanding, only some structures or components are schematically depicted in the drawings, and there may be more or fewer similar structures or components in reality.

[0040] In this application, unless otherwise clearly specified and limited, ordinal numbers, such as "first", "second", etc., are only used to distinguish and describe related objects, and cannot be understood as indicating or implying the relative importance or order between related objects; in addition, they do not represent the number of related objects. "And / or" is used to describe the relationship between related objects, which represents any combination relationship between related objects, for example, "a and / or b" includes: "a alone", "b alone", or "a and b".

[0041] The terms “install”, “set” and “connect” should be understood in a broad sense. For example, “install” can be directly installed or installed through other components; “set” can be directly set or set through other components; “connect” can be directly connected or connected through other components.

[0042] In the embodiments shown in the drawings, directional indications (such as up, down, left, right, front, and back, etc.) are not absolute but relative when describing the structure and movement of each component, and are not used to limit the direction of the product in actual use.

[0043] In the embodiments of the present application, "proximal end" and "distal end" are used to describe the position or direction of the associated (or described) object (referred to as associated object) relative to the operator from the perspective of the operator (for example, a doctor or operator). For example, the "proximal end" refers to the end close to the operator during the normal operation of the medical device by the operator; the "distal end" refers to the end away from the operator during the normal operation of the medical device by the operator, or the end that first enters the patient's body. For example, the "proximal end" of A refers to the end of A close to the operator; the "distal end" of A refers to the end of A away from the operator. Alternatively, the "proximal end" of A refers to the end of A away from the patient (or the affected area, or the target intervention location); the "distal end" of A refers to the end of A close to the patient (or the affected area, or the target intervention location).

[0044] Interventional technology can introduce materials, medical devices, or drugs into the body to perform minimally invasive diagnosis and / or treatment of diseases. Depending on the interventional approach, interventional technology includes, for example, intravascular interventional technology and extravascular interventional technology. The application of intravascular interventional technology is very extensive, for example, intravascular interventional technology is used for intravascular specimen collection, or angiography and other diagnoses; for example, intravascular interventional technology is used for drug infusion, embolization, vascular dilatation and shaping, intravascular stent placement, vascular filter placement, intravascular foreign body or thrombus removal, or intravascular plaque grinding and other treatments; for example, intravascular interventional technology is used to introduce substances into organs such as the heart for diagnosis and / or treatment. It can be seen that by using intravascular interventional technology, materials, medical devices, or drugs can be introduced into the heart, arteries, or veins of an organism. For example, intravascular interventional technology can be used to introduce a transseptal puncture needle, a valve clip, an occluder, or a vascular filter into the lesion site.

[0045] Take the heart as an example: for diseases such as ventricular septal defect (VSD), atrial septal defect (ASD), or patent ductus arteriosus, intravascular interventional treatment technology can be used to deliver the occluder as an interventional material to the lesion site through a catheter to block the defect between the left and right ventricles or the left and right atria, or to block the passage between the aorta and the pulmonary artery. For another example, for diseases such as mitral regurgitation or tricuspid regurgitation, intravascular interventional treatment technology can be used to deliver the valve clip as an interventional material to the lesion site through a catheter to perform edge-to-edge repair of the mitral valve or tricuspid valve.

[0046] The delivery of interventional substances may adopt a delivery system, which may include, for example, a control mechanism and a catheter. The catheter is used to establish a substance delivery channel in a blood vessel, and the regulating component is used to operate the catheter and / or interventional substances at the proximal end.

[0047] The sealing of the delivery system during use is very important for interventional diagnosis and / or treatment. If the sealing is insufficient, gas may enter the blood vessels during delivery; more seriously, it may cause gas embolism in the blood vessels. In addition, insufficient sealing may also cause blood loss. Therefore, the embodiments of the present application provide a sealing device and a control mechanism, a delivery system, and an interventional system provided with the sealing device, which can play a good sealing role during the delivery of the interventional substance to prevent gas from entering the blood vessels and / or blood loss.

[0048] The following is a description with reference to the accompanying drawings.

[0049] Please refer to Figure 1 , which is a schematic diagram of the structure of an intervention system provided in an embodiment of the present application. Figure 1 As shown, the intervention system 10 includes a delivery system 100 and an intervention substance 101. The delivery system 100 is used to deliver the intervention substance 101; the delivery system 100, for example, includes a catheter 110 and a manipulation device 120. The catheter 110 is used to provide a delivery channel for the intervention substance 101, and the manipulation device 120 is used to control the catheter 110 and / or the intervention substance 101. For example, when the intervention substance 101 is an implant, the distal end of the catheter 110 and the intervention substance 101 can be detachably connected under the control of the manipulation device 120; the manipulation device 120 delivers the intervention substance 101 to the target position through the catheter 110 and implants it, and then controls the intervention substance 101 to be detached from the distal end of the catheter 110 and remain in the biological body.

[0050] The catheter 110 may adopt a multi-layer catheter structure, which includes at least two layers of catheters, wherein the outer layer catheter provides an operation channel for other catheters, and the other catheters are used to deliver the interventional material 101. The control device 120 may include multiple control mechanisms for controlling the distal movement of the catheter 110; optionally, it can also control the implantation and removal of the interventional material 101. Figure 1As shown, the delivery system 100 includes, for example, a three-layer catheter structure and a control mechanism corresponding to the three-layer catheter. For example, the catheter 110 includes a guide catheter 111, a control catheter 112, and an inner layer catheter 113; the control device 120 includes a first control mechanism 121, a second control mechanism 122, and a third control mechanism 123, which are respectively used to control the distal movement of the guide catheter 111, the control catheter 112, and the inner layer catheter 113. The control device 120 may also include a loader 124, including a base 1241 and a loading catheter 1242. When in use, the loading catheter 1242 penetrates the proximal end of the first control mechanism 121, becomes a channel for the control catheter 112, the inner layer catheter 113, and the interventional material 101 to enter the guide catheter 111, and the interventional material 101 is loaded into the guide catheter 111 through the first control mechanism 121.

[0051] The valve clamp is used as an example for description as the intervention material 101. The third control mechanism 123 may also include a first handle 1231 and a second handle 1232, which are used to control the states of the capture member and the clamping arm of the valve clamp respectively; Figure 1 Only the first handle 1231 on one side of the third operating mechanism 123 is shown, and the first handle 1231 can also be provided on the other side to control different catch members of the valve clip. Figure 2-Figure 6 , which is a schematic diagram of the implantation process of a valve clipper provided in an embodiment of the present application. During the implantation process, the guide catheter 111 is equipped with a dilator and enters the right atrium along the guide wire through the femoral vein, and the distal end of the guide catheter 111 passes through the atrial septum and enters the left atrium. Then the dilator is withdrawn, and the control catheter 112 is equipped with the inner layer catheter 113 and the valve clipper 200 and enters the left atrium along the inner cavity of the guide catheter 111. Figure 2 As shown, the valve clip 200 is connected to the distal end of the inner catheter 113, and the control catheter 112 and the inner catheter 113 are used to move the valve clip 200 above the leaflet 20, so that the valve clip 200 and the corresponding edge of the leaflet 20 are substantially perpendicular. Figure 3 As shown, the inner catheter 113 delivers the valve clip 200 to the bottom of the leaflet 20 and adjusts the position of the valve clip 200 to make it close to the leaflet 20. The first handle 1231 is operated to control the opening or closing of the catch 210, and the second handle 1232 is operated to control the opening or closing of the clamp arm 220. Figure 4 As shown, when capturing the leaflet 20, the clamping arm 220 is controlled to be in an open state, and the capture member 210 is controlled to be opened so as to approach the clamping arm 220 and capture the leaflet 20 between the two. Figure 5 As shown, the second handle 1232 is operated to move the clamping arm 220 to the closed state, so that the leaflets 20 are apposed. Figure 6As shown, the second handle 1232 is continuously manipulated so that the valve clip 200 is detached from the distal end of the inner layer catheter 113 and remains in the patient's body.

[0052] The above description of the delivery system is only an example. The present application does not limit the shape and number of the catheters of the delivery system, nor does it limit the shape and number of the control mechanisms included in the control device. Delivery systems with different structures can be set according to different interventional materials.

[0053] In a delivery system, when a catheter penetrates into a control mechanism, poor sealing may cause gas to enter a blood vessel and / or blood to be lost. The present application provides a sealing device, which is arranged in a control mechanism, and when a catheter penetrates into the control mechanism, it can play a good sealing role on the catheter's penetration path to prevent gas from entering a blood vessel and / or blood from being lost.

[0054] For example, see Figure 7 and Figure 8 , which shows a structural example of a control mechanism provided in an embodiment of the present application; wherein Figure 7 is a plan view of the control mechanism; Figure 8 for Figure 7 The control mechanism shown is a cross-sectional view along the AA direction. The control mechanism 700 is used to control a catheter (to distinguish the description, it can be called a second catheter). The control mechanism 700 includes a shell 710 and a base 720; the shell 710 has a through hole 711 inside, which is used to accommodate the proximal end of the second catheter. For example, when the control mechanism 700 is the first control mechanism 121, it can accommodate the proximal end of the guide catheter 111; for another example, when the control mechanism 700 is the second control mechanism 122, it can accommodate the proximal end of the control catheter 112. The base 720 is arranged at the proximal end of the shell 710, and has a first opening 721 and a second opening 722; the first opening 721 is connected to the through hole 711, and the second opening 722 is used for the insertion of the catheter (to distinguish the description, it can be called the first catheter). A sealing device 730 is arranged inside the shell 720. The sealing device 730 is disposed between the first opening 721 and the second opening 722, and is used to seal the penetration path of the second catheter when the first catheter passes through the second opening 722 and the first opening 721 to penetrate the through hole 711. For example, when the control mechanism 700 is the first control mechanism 121, the second opening 722 of the base 720 is used for the penetration of the loading catheter 1242. For another example, when the control mechanism 700 is the second control mechanism 122, the second opening 722 of the base 720 is used for the penetration of the control catheter 112. By setting the sealing device 730, the good sealing of the delivery system can be maintained during the delivery of the interventional substance to prevent gas from entering the blood vessel and / or blood loss.

[0055] The sealing device will be described below with reference to the accompanying drawings.

[0056] Please refer to Fig. 9 , which is a schematic diagram of the structure of a sealing device provided in an embodiment of the present application. Fig. 9 As shown, the sealing device 900 includes a flow blocking member 910 and a sealing member 920. Fig.10 and Fig.11 , which are respectively a three-dimensional structural schematic diagram and an axial cross-sectional view of a flow-blocking member provided in an embodiment of the present application. The flow-blocking member 910 includes a flow-blocking portion 911 and a base portion (which may be referred to as a first base portion for distinguishing description) 912; the flow-blocking portion 911 is disposed at a first end of the base portion 912 and includes a unidirectional flow-blocking structure 9111 for preventing liquid from flowing in a first direction. Further in conjunction with reference Fig.12 and Fig.13 , which are respectively a three-dimensional structural schematic diagram and an axial cross-sectional view of a seal provided in an embodiment of the present application. The seal 920 includes a bottom 921 and a connecting portion 922. The bottom 921 has a through hole 9211. The connecting portion 922 matches the base 912 to connect the seal 920 to the second end of the base 912.

[0057] When the sealing member 920 is connected to the base 912, a first space is formed between the bottom 921 and the one-way flow blocking structure 9111. In the second direction, the through hole 9211 is used for the first conduit to pass through the first space, and the one-way flow blocking structure 9111 is used for the first conduit to pass through the first space, and when the first conduit passes through the first space, the through hole 9211 is sealed by the first conduit, and the one-way flow blocking structure 9111 is attached to the first conduit. The first direction is the direction from the flow blocking member 910 to the sealing member 920, and the second direction is the direction from the sealing member 920 to the flow blocking member 910.

[0058] When the above sealing device is used, when the distal end of the first catheter (such as a loading catheter or a control catheter) penetrates the control mechanism, it passes through the through hole 9211 of the sealing member 920 and enters the first space; then penetrates the one-way flow blocking structure 9111 of the flow blocking member 910, passes out of the first space, and enters the through hole of the control mechanism; docks with the proximal end of the second catheter accommodated in the control mechanism or penetrates the proximal end of the second catheter. At this time, although the one-way flow blocking structure 9111 of the flow blocking member 910 is opened, the connecting portion 922 of the sealing member 920 can still close the first space to prevent gas from entering the first space from the outside, and blood is still retained to prevent blood from leaking out of the first space.

[0059] It can be seen that the above sealing device can achieve a two-way sealing effect, and the sealing performance of the control mechanism is significantly improved; it can prevent air from entering the blood vessels through the control mechanism, reducing the risk of air embolism, and prevent blood from flowing back and leaking out, reducing damage to the organism and reducing pollution to the surgical environment.

[0060] In some embodiments of the present application, Fig.10 and Fig.11 As shown, the unidirectional flow-blocking structure 9111 includes a plurality of membrane flaps M1-Mn (where n is a positive integer greater than or equal to 2). In the figure, n is taken as an example of 4, and there may be more or fewer membrane flaps. A flow-blocking space is formed between adjacent membrane flaps, which is used to block the liquid flowing in the first direction in the flow-blocking space. For example, a flow-blocking space is formed between the membrane flap M1 and the membrane flap M2, a flow-blocking space is formed between the membrane flap M2 and the membrane flap M4, a flow-blocking space is formed between the membrane flap M4 and the membrane flap M3, and a flow-blocking space is formed between the membrane flap M3 and the membrane flap M1. Optionally, the membrane flap can also be called a membrane-like interval, and the flow-blocking portion 911 includes a flow-blocking space divided by a plurality of membrane-like intervals, and adjacent membrane-like intervals are arranged to be connected at the proximal end to form a side with an arc-shaped edge on the axial section, and the distal ends of the plurality of membrane-like intervals abut against each other, and can be separated by an external force from the proximal end to the distal end (i.e., the second direction) along the central axis.

[0061] Thus, when the flow blocking space is filled with liquid and subjected to liquid pressure in the first direction, multiple membrane petals (or membrane-like intervals gather together) retain the liquid in the flow blocking portion 911. The one-way flow blocking structure is simple in structure, low in cost, and has a good flow blocking effect.

[0062] In some embodiments of the present application, the flow blocking portion 911 includes a tube body 9112, which is hollow inside and is disposed at the first end of the base 912. Multiple membrane petals M1-Mn are disposed inside the tube body 9112, and one side edge of the multiple membrane petals M1-Mn is connected to the inner wall of the tube body 9112, and the other side edges of adjacent membrane petals are connected to form multiple connection edges L; the distance between the multiple connection edges L gradually decreases along the second direction until they abut against each other.

[0063] The connecting edge L formed by connecting adjacent membrane flaps can make the bottom of the flow-blocking space closed in the first direction. Multiple connecting edges L abut against each other, so that when the first catheter passes between the connecting edges L, a certain gap can be opened between the connecting edges L for the first catheter to pass through. For example, when the first catheter passes through the abutting portion between the connecting edges L along the second direction, the abutting area is pushed open, and the abutting portion will fit against the outer wall of the first catheter, and can still provide a certain sealing when the first catheter passes through. When blood refluxes during surgery, the blood flows in the first direction and flows into the flow-blocking space, and the blood will be retained in the flow-blocking space. As the amount of blood retention increases, the pressure of the blood on the membrane flap will increase the fitting area between the connecting edge L and the outer wall of the first catheter, further improving the sealing and preventing blood leakage.

[0064] In addition, the distance between the multiple connecting edges L gradually decreases along the second direction until they abut against each other, so that the size of the first space can be gradually reduced along the second direction, which plays a guiding role for the inserted first catheter and is more conducive to the insertion of the first catheter. When the first catheter is inserted, the connecting edge can better fit the first catheter, further improving the sealing performance.

[0065] In some embodiments of the present application, the connecting edge L may be an arc-shaped edge. In this way, the blocking space may have an arc-shaped inner wall, and blood may flow into the blocking space along the arc-shaped inner wall, thereby achieving the effect of blood diversion and buffering, and preventing the blood from exerting excessive pressure on the blocking space, causing undesirable deformation of the blocking space and resulting in poor sealing.

[0066] The above multiple membrane petals (or membrane-like intervals) are centrally symmetrically distributed inside the tube body 9112. When the membrane petals are arranged in this way, each flow-blocking space is evenly distributed, the force is evenly applied, and the sealing performance is better.

[0067] The present application does not limit the connection method between the membrane petals M1-Mn and the inner wall of the tube body 9112. For example, the membrane petals M1-Mn can be connected to the inner wall of the tube body 9112 by adhesive, or can be integrally formed and connected to the inner wall of the tube body 9112, or can be connected to the inner wall of the tube body 9112 by methods such as heat pressing or chemical bonding. Similarly, the present application does not limit the connection method between adjacent membrane petals. For example, any of the above connection methods can be used for connection.

[0068] In some embodiments of the present application, the inner contour of the second end of the base 912 matches the outer contour of the connecting portion 922, or the outer contour of the second end of the base 912 matches the inner contour of the connecting portion 922, so as to achieve the connection between the baffle 910 and the seal 920 by snapping the inner contour of the second end of the base 912 with the outer contour of the connecting portion 922.

[0069] Please continue to refer to Figure 9-12 , the inner contour of the second end of the base 912 matches the outer contour of the connecting portion 922 as an example for description. The base 912 includes an annular wall 9121 and an annular wall 9122. The outer contour of the annular wall 9121 is larger than the outer contour of the flow blocking portion 911, and the outer contour of the annular wall 9122 is larger than the outer contour of the annular wall 9121, forming a stepped shape, which is conducive to matching and connecting with other components in the base 720, preventing the sealing device from loosening in the base 720, resulting in poor sealing. The inner contour of the annular wall 9122 matches the outer contour of the connecting portion 922, which is conducive to the docking between the flow blocking member 910 and the sealing member 920.

[0070] In some embodiments of the present application, the connecting portion 922 is an annular structure, which is convenient for assembly and / or disassembly. In addition, the annular structure of the annular wall 9122 and the connecting portion 922 prevents the flow blocker 910 and the sealing member 920 from being offset or misaligned in the circumferential direction.

[0071] In some embodiments of the present application, the height of the connecting portion 922 may match the height of the annular wall 9122, so as to abut the connecting surface of the annular wall 9121 and the annular wall 9122 when connected. In some embodiments of the present application, the thickness of the connecting portion 922 may match the thickness of the connecting surface of the annular wall 9121 and the annular wall 9122, or may be greater than or less than the thickness of the connecting surface of the annular wall 9121 and the annular wall 9122. In some embodiments of the present application, the size of the outer contour of the annular wall 9122 may be consistent with the outer contour size of the bottom, so that when the spoiler 910 and the sealing member 920 are connected together, they may have consistent outer contour sizes, which is beneficial to the installation of the sealing device in the control mechanism.

[0072] In some other embodiments, the base 912 and the connecting portion 922 may also be connected in other forms, for example, by other mechanical structures. In some other embodiments, the contour of the second end of the base 912 may also be in other shapes, for example, polygonal, elliptical, regular, or irregular shapes, etc.; the contour of the connecting portion 922 may be in other shapes matching therewith.

[0073] In some embodiments of the present application, the above sealing device may further include a guide member 930 for guiding the penetration of the first conduit so that the first conduit can more smoothly penetrate the through hole 9211. The following is described in conjunction with the accompanying drawings.

[0074] Please refer to Fig.14 , which is a schematic diagram of the structure of another sealing device provided in an embodiment of the present application. Fig.14 As shown, it is Fig. 9 The difference of the illustrated embodiment is that the sealing device 900 ′ further includes a guide member 930 connected to the sealing member 920 for guiding the penetration of the first conduit so that the first conduit can penetrate the through hole 9211 of the sealing member 920 more smoothly.

[0075] In some embodiments of the present application, Figure 12-13 The sealing member 920 may further include a base 923 (which may be referred to as a second base for distinguishing description), the connecting portion 922 is disposed at a first end of the bottom 921, and the base 923 is disposed at a second end of the bottom. Fig.15 and Fig.16, which are respectively a three-dimensional structural schematic diagram and an axial cross-sectional view of a guide member provided in an embodiment of the present application. The guide member 930 includes a guide body 931, the interior of the guide body 931 is hollow and is provided with a guide structure 932. The outer wall of the guide body 931 matches the base 923, and the guide member 930 is connected to the second end of the bottom 921 of the seal 920. When the guide member 930 is connected to the base 923, a second space is formed between the guide structure 932 and the bottom 921. The guide structure 932 has a guide hole 9321 for the first conduit to pass through the second space, and a through hole 9211 for the first conduit to pass through the second space, and the guide hole 9321 and the through hole 9211 are coaxial in center.

[0076] By providing the guide member, the first catheter can pass through the sealing device more smoothly, thereby improving the convenience of operation of the conveying system and reducing the damage that may be caused to the sealing member or the control mechanism by misaligned operation.

[0077] In some embodiments of the present application, the guide structure 932 includes a dome structure protruding in the second direction, and the guide hole 9321 is arranged at the center of the dome structure. The dome structure gradually reduces the size of the third space, which is conducive to guiding the penetration of the first catheter, and has the ability to disperse force, has better stability, and thus has a longer service life. In some other embodiments of the present application, the guide structure 932 can also be other structures, for example, a stepped structure, so that the size of the third space is gradually reduced in a stepped manner; for example, an inverted cone structure, so that the size of the third space is gradually reduced in a cone shape; for example, a partial spindle-shaped structure, so that the size of the third space is gradually reduced in a spindle shape, and so on.

[0078] In some embodiments of the present application, the guide hole 9321 is a round hole, a cross hole, or a hole of other shapes. The present application does not limit this. When the guide hole is a cross hole, it is more conducive to the insertion of the first catheter.

[0079] Similar to the above description, a connection structure of an annular wall can also be used between the seal 920 and the guide 930. For example, in some embodiments of the present application, the base 923 includes an annular wall 9231 and an annular wall 9232. The inner contour of the annular wall 9232 is larger than the inner contour of the annular wall 9231. The guide body 931 of the guide 930 includes an annular wall 9312 and annular wall 9311. The outer contour of the annular wall 9312 matches the inner contour of the annular wall 9232, and / or, the outer contour of the annular wall 9311 matches the inner contour of the annular wall 9231. In this way, the seal 920 and the guide 930 can be snapped together, which is convenient for assembly and / or disassembly. In addition, the connection structure of the annular wall is set to prevent the seal 920 and the guide 930 from being offset or misaligned in the circumferential direction.

[0080] When the outer contour of the annular wall 9312 matches the inner contour of the annular wall 9232, and the outer contour of the annular wall 9311 matches the inner contour of the annular wall 9231, a stepped snap-fit ​​structure can be formed to further enhance the stability of the connection between the seal 920 and the guide member 930.

[0081] In some embodiments of the present application, the guide body 931 further includes a base 9313 , so that when the seal 920 and the guide member 930 are connected, the base 923 can abut against the base 9313 to further enhance the stability of the connection.

[0082] Similar to the connection between the sealing member 920 and the flow blocking member 910, in some other embodiments, the sealing member 920 and the guide member 930 may be connected in other forms, for example, by other mechanical structures. In some other embodiments, the inner contour of the base 923 may also be in other shapes, for example, polygonal, elliptical, regular, or irregular shapes, etc.; the outer wall contour of the guide body 931 may be in other shapes matching therewith.

[0083] In some embodiments of the present application, the guide member 930 further includes a first support structure and / or a second support structure. The first support structure includes a plurality of first support members 933, which are supported on the first end face of the guide structure 932, wherein the first end face is the end face of the guide structure 932 facing the second direction. The second support structure includes a plurality of second support members 934, which are supported on the second end face of the guide structure 932, wherein the second end face is the end face of the guide structure 932 facing the first direction. By setting at least one of the above support structures, the strength of the guide member can be enhanced, making it less likely to deform under the influence of external force, thereby extending the service life of the sealing device.

[0084] Although the figure takes four first support members 933 as an example, it is only an example, and the number of first support members 933 can be more or less; it can be an odd number or an even number. Similarly, the present application does not limit the number of second support members 934. In addition, the number of first support members 933 and second support members 934 can be the same or different; the position of the first support member 933 and the position of the second support member 934 can be set relative to each other, or can be staggered, which is not limited by the present application.

[0085] In some embodiments of the present application, a plurality of first support members are centrally symmetrically distributed around the guide hole; and / or a plurality of second support members are centrally symmetrically distributed around the guide hole. In this way, the overall force of the guide structure is more uniform, with better support effect, and the service life of the sealing device is further extended.

[0086] In some embodiments of the present application, the components of the sealing device 900 (e.g., the flow blocker 910 and the seal 920; and the flow blocker 910, the seal 920 and the guide 930) can be made of an elastic material, such as silicone. In this way, the sealing device can be elastically deformed under the influence of external force, but has a tendency to return to its original state after the external force is removed, so as to prevent the deformation caused by the external force during use, which causes the sealing performance to decrease. In addition, the connection between the components is easier to achieve through snap-on connection, which is convenient for assembly and / or disassembly.

[0087] In some other embodiments of the present application, the one-way flow blocking structure 9111 of the flow blocking member 910, the portion of the bottom 921 of the sealing member 920 between the connecting portion 922 and the through hole 9211, and the guide structure 932 of the guide member 930 may all or partly be made of elastic material. The other parts of the sealing device may be made of non-elastic material, and a sealing ring may be provided at the connected part, for example, a sealing ring may be provided between the connecting portion 922 and the base 912; for another example, a sealing ring may be provided between the base 923 and the outer wall of the guide body 931.

[0088] In some other embodiments of the present application, the components of the above sealing device can be made of biocompatible materials to improve medical safety.

[0089] When any of the above sealing devices is used in a conveying system, the sealing performance of the conveying system can be improved. Figure 1 Taking the guide catheter 111 and the control catheter 112 as an example, when the distal end of the control catheter 112 passes through the first control mechanism 121 of the guide catheter 111, it sequentially enters the third space, passes through the guide hole 9321 of the guide member 930, passes through the through hole 9211 of the sealing member 920, opens the one-way flow blocking structure 9111, enters the through hole 711 of the first control mechanism 121, and then enters the proximal end of the guide catheter 111 accommodated in the first control mechanism 121. At this time, although the distal end of the one-way flow blocking structure 9111 of the blocking member 910 is opened, the connecting portion 922 of the sealing member 920 can still close the first space between the blocking member 910, and the blood is still retained, thereby preventing blood leakage. In addition, gas is prevented from entering from the outside. Furthermore, the guide member 930 guides the distal end of the control catheter 112 to enter the through hole of the sealing member 920; in addition, the guide member 930 has a supporting strength and is not easily deformed under the influence of external forces. During use, it still has good sealing performance when facing the repeated entry and exit of the catheter.

[0090] In some embodiments of the present application, any of the above sealing devices can be used for a control mechanism, and the control mechanism is used to control the second catheter; for example, the control mechanism can adjust the curvature of the distal end of the second catheter, control the end point of the distal end of the second catheter, and make it easier for the interventional material to reach a more ideal relative position with the lesion position (for example, repair tissue). Please continue to refer to Figure 7 and Figure 8 In some embodiments of the present application, the control mechanism 700 may further include an adjustment component 740 and a steering component 750. The adjustment component 740 is used to provide an operating end to the user, and the adjustment component 740 obtains a force under the operation of the user, and the force drives the movement of the adjustment component 740; the movement of the adjustment component 740 drives the movement of the steering component 750. The steering component 750 is connected to the proximal end of the pull wire, and the distal end of the pull wire is fixed to the distal end of the second catheter. The movement of the steering component 750 can drive the proximal end of the pull wire to move, thereby controlling the bending state of the distal end of the second catheter. The control mechanism 700 may also include a central rod 760, and the central rod 760 is hollow inside to form a through hole 711.

[0091] The following further combines Fig.17 740 includes an operating element 741 and a threaded tube 742. The distal end of the threaded tube 742 is connected to the operating element 741. Rotating the operating element 741 can drive the threaded tube 742 to rotate together. The threaded tube 742 can be sleeved outside the center rod 760. Fig.18 , which is a schematic diagram of the structure of a steering assembly provided in an embodiment of the present application. Fig.18As shown, the steering assembly 750 includes a rotating member 751 and a sliding member 752 abutting against the rotating member 751. The rotating member 751 and the sliding member 752 can be sleeved on the central rod 760. The rotating member 751 is provided with a wire hole 7511 axially penetrating its wall. The wire 180 extends from the distal end of the second catheter to the rotating member 751, passes through the wire hole 7511, and is arranged on the sliding member 752. For example, the sliding member 752 is provided with a fixing member 753 and a pin 754 penetrating the fixing member 753. The proximal end of the wire 180 passes through the wire hole 7511 and is connected to the fixing member 753 by the pin 754 (for example, the wire 180 is wound around the pin 754). The internal shape of the cross section of the rotating member 751 and the sliding member 752 is adapted to the external shape of the cross section of the central rod 760. The rotating member 751 is provided with an external thread, which matches the internal thread of the threaded tube 742. In this way, when the operating element 741 is rotated, the operating element 741 can drive the rotation of the threaded tube 742; the rotation of the threaded tube 742 can drive the rotating member 751 to move axially along the center rod 760, and then drive the sliding member 752 to move axially along the center rod 760 toward the proximal end; the movement of the sliding member 752 drives the pull wire 180 to move proximally, thereby pulling the distal end of the second catheter to cause it to bend.

[0092] In some embodiments of the present application, the outer contour (i.e., the outer shape of the cross section) of the center rod 760 is a non-circular contour, and the inner contours (i.e., the inner shape of the cross section) of the rotating member 751 and the sliding member 752 match the outer contour of the center rod 760, so that the radial movement between the center rod 760 and the rotating member 751 and the sliding member 752 can be limited. When the threaded tube 742 rotates, since the inner contour of the rotating member 751 and the outer contour of the center rod 760 are both non-circular contours, the two are abutted due to the rotation, which limits the radial rotation of the rotating member 751 and converts the radial rotation into axial movement, so that the rotating member 751 moves along the axial direction of the center rod 760, thereby driving the sliding member 752 to move axially.

[0093] The present application does not limit the outer contour shape of the center rod 760, which can be a regular shape or an irregular shape. For example, it can be an ellipse, a rectangle, a triangle, or other polygons; for example, it can be a runway shape, including two parallel sides connected by symmetrical arc sides between the two sides.

[0094] In some embodiments of the present application, the above control mechanism 700 may further include an indication assembly 770. The indication assembly 770 is connected with the adjustment assembly 740. When the adjustment assembly 740 moves, the indication assembly 770 moves synchronously to indicate the bending state of the distal end of the second catheter. The indication assembly 770 includes an indication member 771 and an indication plate 772. Different bending state marks are provided on the indication plate 772, which can be displayed to the user through the indication window 712 of the housing 710. The indication member 771 is slidably connected to one side of the indication plate 772, and its position on the indication plate 772 is used to indicate the bending state of the distal end of the second catheter. In some embodiments, the inner side of the indication member 771 is provided with a thread, which matches the outer thread of the threaded tube 742; the outer side of the indication member 771 is slidably connected to the indication plate 772, so that when the threaded tube 742 rotates, the indication member 771 can move relative to the indication plate 772, so that the user can more intuitively understand the bending state of the distal end of the second catheter.

[0095] In some embodiments of the present application, the above control mechanism 700 may further include a supporting element 780 for supporting the proximal end of the second catheter.

[0096] The present application also provides a catheter, which can be a guide catheter, a control catheter, or an inner catheter in the above embodiments. Alternatively, the catheter can be the second catheter in the above embodiments. The distal end of the catheter has better stability during the bending control, which is conducive to providing distal stability of the delivery system. When the above control mechanism controls the catheter, it can not only improve the sealing performance of the delivery system, but also improve the distal stability of the delivery system.

[0097] The following is a description with reference to the accompanying drawings.

[0098] Please refer to Fig.19 , which is a schematic diagram of the structure of the distal end of a catheter provided in an embodiment of the present application. The upper view is a view of the first side of the distal end of the catheter, and the upper view is a view of the second side of the distal end of the catheter, and the first side and the second side are opposite. Fig.19 As shown, a pull-wire channel 191 is provided in the catheter 190, and the pull-wire channel 191 is provided on the inner side of the catheter 190 near the first side. When the pull-wire passes through the pull-wire channel 191 and is pulled toward the proximal end, the distal end of the catheter 190 is bent, the first side is concave, the second side is convex, and the distal end of the catheter 190 is bent toward the first side.

[0099] The distal end of the catheter 190 is also provided with a support structure 192 and a pull wire fixing structure 193. The support structure 192 is used to provide support for the distal end of the catheter 190 so that the bending of the distal end of the catheter is stable and has sufficient supporting force. The pull wire fixing structure 193 is used to fix the distal end of the pull wire. The present application does not limit the form of the pull wire fixing structure. For example, the pull wire fixing structure 193 may include an annular structure, which is sleeved on the distal end of the pull wire. The annular structure is, for example, a metal ring. In some other embodiments, for example, it is a protruding structure or a hole structure provided at the distal end of the catheter.

[0100] In some embodiments of the present application, a developing structure is also provided at the distal end of the catheter 190 to indicate the position of the distal end of the catheter. In some embodiments, the pull-wire fixing structure 193 can have a developing function, that is, the pull-wire fixing structure is also a developing structure. For example, the pull-wire fixing structure 193 can be made of metal and can be used with medical imaging equipment for development, thereby showing the position of the distal end of the catheter to the user during surgery.

[0101] In some embodiments of the present application, the pull wire fixing structure 193 may not be provided, and the support structure 192 also has the function of fixing the pull wire. The distal end of the pull wire is fixed to the distal end of the support structure 192. The support structure 192 has a larger axial dimension, which provides a stronger pulling force for the pull wire, so that the bending stability of the distal end of the catheter is further improved. Optionally, the distal end of the support structure 192 may be provided with a developing structure, or the part of the support structure 192 used to fix the pull wire also has a developing function. For example, the developing structure is made of metal material or the part of the support structure 192 used to fix the pull wire is made of metal material.

[0102] The support structure 192 includes a first side 1921 (corresponding to the first side of the distal end of the catheter 190) and a second side 1922 (corresponding to the second side of the distal end of the catheter 190), and the distance between the pull wire channel 191 and the first side is less than the distance between the pull wire channel 191 and the second side 1922. The support structure 192 has a certain elasticity, so that it can provide support for the distal end of the catheter and can follow the bending deformation of the distal end of the catheter. For example, in some embodiments, the support structure 192 includes a plurality of support segments 1923, the plurality of support segments 1923 are connected on the first side 1921, and there is a non-penetrating first hollow structure 1924 between the two ends of the first side 1921; the plurality of support segments 1923 have a penetrating second hollow structure 1925 between the two ends of the second side 1922. In this way, when the pull wire is pulled toward the proximal end, the support structure 192 follows the bending of the distal end of the catheter 190, the first side 1921 is recessed, and the second side 1922 is convex to support the bending state of the distal end of the catheter 190.

[0103] In some embodiments of the present application, the catheter 190 is a multi-layer structure, for example, including an inner layer structure 193 and an outer layer structure 194, and the support structure 192 is arranged between the inner layer structure 193 and the outer layer structure 194, so that the distal end of the catheter 190 remains smooth, thereby reducing possible damage to the organism during the process of delivering the interventional substance.

[0104] The embodiment of the present application also provides a delivery system, which includes a second catheter and a control mechanism, the control mechanism is used to control the second catheter, and any of the above sealing devices is arranged in the control mechanism. In some embodiments of the present application, the control mechanism can be used to control the bending shape of the distal end of the second catheter. The second catheter can have the structure of the distal end of the catheter in the above embodiment; the above delivery system also includes a pull wire 180, the pull wire 180 passes through the pull wire channel 191, the distal end is fixed to the pull wire fixing structure 193, and the proximal end is connected to the control mechanism; the control mechanism controls the bending state of the distal end of the catheter 190 through the pull wire.

[0105] The present application also provides an intervention system, including an intervention substance and a delivery system for delivering the intervention substance. The delivery system includes any one of the control mechanisms in the above embodiments, and / or any one of the catheters in the above embodiments.

[0106] The above embodiments can be freely combined as needed. The above are only some implementation methods of the present application. For ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the present application, and these improvements and modifications should also be regarded as the protection scope of the present application.

Claims

1. A sealing device, characterized in that: include: A flow blocking member, comprising a flow blocking portion and a first base portion, wherein the flow blocking portion is arranged at a first end of the first base portion and comprises a one-way flow blocking structure for blocking the flow of liquid in a first direction; A sealing member, comprising a bottom and a connecting portion, wherein the bottom has a through hole, and the connecting portion matches the first base portion to connect the sealing member to the second end of the first base portion; When the sealing member is connected to the first base, a first space is formed between the bottom and the one-way flow blocking structure, and in the second direction, the through hole is used for the first conduit to pass through the first space, and the one-way flow blocking structure is used for the first conduit to pass through the first space, and when the first conduit passes through the first space, the through hole is sealed by the first conduit, and the one-way flow blocking structure is attached to the first conduit; The first direction is a direction from the blocking member to the sealing member, and the second direction is a direction from the sealing member to the blocking member.

2. The sealing device according to claim 1, characterized in that: The one-way flow-blocking structure includes a plurality of membrane petals, and a flow-blocking space is formed between adjacent membrane petals, which is used to block the liquid flowing along the first direction in the flow-blocking space.

3. The sealing device according to claim 2, characterized in that: The flow blocking portion includes a tube body, the interior of the tube body is hollow, and is arranged at the first end of the first base; The plurality of membrane petals are arranged inside the tube body, and one side edge of the plurality of membrane petals is connected to the inner wall of the tube body, and the other side edges of adjacent membrane petals are connected to form a plurality of connection edges; The distances between the plurality of connecting edges gradually decrease along the second direction until they abut against each other.

4. The sealing device according to claim 3, characterized in that: The connecting edge is an arc-shaped edge.

5. The sealing device according to claim 3, characterized in that: The plurality of membrane petals are centrally and symmetrically distributed inside the tube body.

6. The sealing device according to claim 1, characterized in that: The inner contour of the second end of the first base portion matches the outer contour of the connecting portion; or, The outer contour of the second end of the first base portion matches the inner contour of the connecting portion.

7. The sealing device according to claim 1, characterized in that: The sealing member further comprises a second base, the connecting portion is arranged at a first end of the bottom portion, and the second base is arranged at a second end of the bottom portion; The sealing device further comprises a guide member, comprising a guide body, the interior of the guide body is hollow and provided with a guide structure, the outer wall of the guide body matches the second base, and the guide member is connected to the second end of the bottom of the sealing member; When the guide member is connected to the second base, a second space is formed between the guide structure and the bottom, and the guide structure has a guide hole for the first conduit to pass through the second space, and the through hole is used for the first conduit to pass through the second space, and the guide hole and the through hole center are coaxial.

8. The sealing device according to claim 7, characterized in that: The guide structure includes a dome structure protruding toward the second direction, and the guide hole is arranged at the center of the dome structure.

9. The sealing device according to claim 7, characterized in that: The guide hole is a cross hole.

10. The sealing device according to claim 7, characterized in that: The guide member further comprises at least one of the following supporting structures: A first supporting structure, comprising a plurality of first supporting members, supported on a first end surface of the guide structure, wherein the first end surface is an end surface of the guide structure facing the second direction; The second supporting structure includes a plurality of second supporting members, and is supported on a second end surface of the guiding structure, wherein the second end surface is an end surface of the guiding structure facing the first direction.

11. The sealing device according to claim 10, characterized in that: The guide member includes the first support structure and the second support structure, and a plurality of the first support members are centrally symmetrically distributed around the guide hole; a plurality of the second support members are centrally symmetrically distributed around the guide hole.

12. A control mechanism for controlling a second catheter, characterized in that: include: A housing, wherein the housing has a through hole therein for accommodating the proximal end of the second catheter; A base, disposed at the proximal end of the housing, having a first opening and a second opening, wherein the first opening is communicated with the through hole, and the second opening is used for the first catheter to penetrate; The sealing device according to any one of claims 1 to 11 is arranged between the first opening and the second opening, and is used to seal the penetration path of the first conduit when the first conduit penetrates into the through hole through the second opening and the first opening.

13. A conveying system, characterized in that: include: Second catheter; The control mechanism of claim 12, adapted to control the second conduit.

14. The conveying system according to claim 13, characterized in that A pull wire channel is provided in the second catheter, and a support structure and a pull wire fixing structure are provided at the distal end of the second catheter; The delivery system further includes a pull wire, the pull wire passes through the pull wire channel, the distal end of the pull wire is fixed to the pull wire fixing structure, the proximal end of the pull wire is connected to the control mechanism, and the control mechanism controls the bending state of the distal end of the second catheter through the pull wire; The support structure includes a first side and a second side, and a distance between the wire pulling channel and the first side is smaller than a distance between the wire pulling channel and the second side.

15. The conveying system according to claim 14, characterized in that The support structure includes a plurality of support segments, the plurality of support segments are connected on the first side and have a non-through first hollow structure between the two ends of the first side, and the plurality of support segments have a through second hollow structure between the two ends of the second side.

16. An interventional system, characterized in that: include: Intervention substances; The delivery system according to any one of claims 13 to 15, for delivering the intervention substance.

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