Reagent product preparation functional island
By designing the functional island for reagent product preparation, and using an automated transport device to transport orifices between storage, liquid separation, membrane sealing and other devices, the problem of time-consuming, labor-intensive and low efficiency in the preparation process of reagent product in the prior art is solved, and more efficient automated production is achieved.
Patent Information
- Application Number
- CN202421488769.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-27
- Publication Date
- 2025-04-22
- Estimated Expiration
- 2034-06-27
AI Technical Summary
In the prior art, the preparation process of reagent products is time-consuming and labor-intensive, with low production efficiency and relies on a large number of manual operations.
A functional island for preparing reagent products is designed, including storage devices, liquid separation devices, membrane sealing devices and transport devices. Through the transport device, the orifice plates are automatically transferred between these devices to realize the automated reagent aliquoting and membrane sealing process.
Through automated transport and operation, manual handling and operation time is reduced, the preparation efficiency of reagent products is improved, and the working intensity is reduced.
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Figure CN222780689U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the field of reagent packaging equipment, in particular to a reagent product preparation function island. Background Art
[0002] With the increasing market demand for biological reagent detection products, existing reagent product preparation processes have gradually revealed existing problems, especially in the reagent packaging process, which is highly dependent on manual operation and requires several experimenters. The preparation process is to manually stick the label to the well plate, then operate to distribute the reagent into the well plate, and then manually seal the well plate with the liquid. In each process, personnel are required to manually load and unload the plate and transfer it to the equipment for the next step. Since manual labeling, well plate sealing, and liquid distribution steps are time-consuming and labor-intensive, and there are many manual operation steps and a large workload, the packaging preparation of reagent products has technical problems such as time-consuming, labor-intensive, and low efficiency. Therefore, in order to meet market demand, it is urgent to improve the existing preparation model to improve the efficiency of product preparation. Summary of the invention
[0003] The utility model mainly solves the technical problem that the preparation process of the reagent product in the prior art is time-consuming and labor-intensive, and the production efficiency of the product is low.
[0004] The utility model provides a reagent product preparation functional island, comprising:
[0005] at least one storage device having a storage portion for placing the orifice plate;
[0006] at least one dispensing device for dispensing reagents into the well plate;
[0007] A sealing device, used for sealing the well plate after the reagent is dispensed into the well plate;
[0008] And a transfer device, at least two of the storage device, the liquid separation device and the film sealing device are located within the transfer range of the transfer device, so that the transfer device can transfer the well plate between at least two of the storage device, the liquid separation device and the film sealing device.
[0009] In an optional embodiment, the reagent product preparation functional island further includes a labeling device for attaching a label to the well plate;
[0010] The labeling device is located within the transfer range of the transfer device, and the transfer device can transfer the well plate between the labeling device and at least one of the storage device, the liquid dispensing device and the film sealing device.
[0011] In an optional embodiment, the transfer device is a transfer robot, and the storage device, labeling device, liquid separation device and film sealing device are all distributed within the transfer range of the transfer robot, and the orifice plate transfer between the devices is achieved by the same transfer robot.
[0012] In an optional embodiment, the liquid dispensing device includes a liquid dispensing component and at least one liquid storage chamber for storing reagents, and the liquid dispensing component is connected to the liquid storage chamber and is used to inject the reagents in the liquid storage chamber into the well plate.
[0013] In an optional embodiment, the number of the liquid-dispensing components is the same as the number of the liquid-storing chambers, and the liquid-dispensing components are connected to the liquid-storing chambers in a one-to-one correspondence.
[0014] In an optional embodiment, the reagent product preparation functional island further includes a stirring device, wherein the stirring device is provided with a stirring portion, and the stirring portion is used to extend into the liquid storage cavity and stir the reagent.
[0015] In an optional embodiment, the reagent product preparation functional island further includes a first base, and the liquid separation device and the film sealing device are arranged on the first base.
[0016] In an optional embodiment, the reagent product preparation functional island also includes a second base, the transfer device is arranged on the second base, and the second base is arranged between the first base and the storage device.
[0017] In an optional embodiment, the bottom of the first base has a first running wheel assembly and a first supporting leg assembly, and at least one of the first running wheel assembly and the first supporting leg assembly is a height-adjustable structure, so that the first base can be switched between two states of contacting the ground through the first running wheel assembly and contacting the bottom surface through the first supporting leg assembly;
[0018] And / or, a second walking wheel assembly and a second supporting leg assembly are provided at the bottom of the second base, and at least one of the second walking wheel assembly and the second supporting leg assembly is a height-adjustable structure so that the second base can switch between two states of contacting the ground through the second walking wheel assembly and contacting the bottom surface through the second supporting leg assembly.
[0019] In an optional embodiment, the reagent product preparation functional island further includes an electrically connected human-machine interaction device and a control device, and the control device is used to at least control the transport device.
[0020] According to a reagent product preparation functional island of the above embodiment, the well plate to be used can be placed on the storage part of the storage device. The transfer operation in the production process at least includes moving the well plate from the storage device to the liquid separation device, transferring from the liquid separation device to the film sealing device, and transferring from the film sealing device to the storage device, and finally the product encapsulated with the reagent can be stored in the storage device. At least two of the storage device, the liquid separation device and the film sealing device are located within the transfer range of the transfer device, and the transfer device is used to transfer the well plate between at least two of the storage device, the liquid separation device and the film sealing device. That is to say, in the above three transfer operations, at least one transfer operation is automatically realized by the transfer device, which can at least reduce the time consumption of the corresponding transfer operation. Compared with the related technology, it can reduce the workload of manual handling and transfer to a certain extent, which is conducive to improving the preparation efficiency of the product. BRIEF DESCRIPTION OF THE DRAWINGS
[0021] Figure 1 Schematic diagram of the overall structure of the functional island for preparing reagent products provided in some embodiments of the present application.
[0022] Figure 2 for Figure 1 Schematic diagram of the structure of the first base.
[0023] Figure 3 for Figure 1 Schematic diagram of the structure of the second base.
[0024] Figure numerals: 100-reagent product preparation functional island; 10-transport device; 20-storage device; 30-liquid dispensing device, 31-liquid dispensing assembly, 32-liquid storage chamber; 40-film sealing device; 50-labeling device; 60-stirring device, 61-stirring part; 70-first base; 71-first walking wheel assembly, 72-first support leg assembly; 73-light bar; 80-second base; 81-second walking wheel assembly, 82-second support leg assembly; 83-buffer block; 84-connecting block; 85-reinforced frame; 90-human-computer interaction device. DETAILED DESCRIPTION
[0025] The present invention is further described in detail below by specific embodiments in conjunction with the accompanying drawings. Wherein similar elements in different embodiments adopt associated similar element numbers. In the following embodiments, many detailed descriptions are intended to enable the present application to be better understood. However, those skilled in the art can easily recognize that some of the features can be omitted in different situations, or can be replaced by other elements, materials, and methods. In some cases, some operations related to the present application are not shown or described in the specification, in order to avoid the core part of the present application being overwhelmed by too much description, and for those skilled in the art, it is not necessary to describe these related operations in detail, and they can fully understand the related operations based on the description in the specification and the general technical knowledge in the art.
[0026] In addition, the features, operations or characteristics described in the specification can be combined in any appropriate manner to form various implementations. At the same time, the steps or actions in the method description can also be interchanged or adjusted in a manner that is obvious to those skilled in the art. Therefore, the various sequences in the specification and the drawings are only for the purpose of clearly describing a certain embodiment and are not meant to be a required sequence, unless otherwise specified that a certain sequence must be followed.
[0027] The serial numbers assigned to the components herein, such as "first", "second", etc., are only used to distinguish the objects described and do not have any order or technical meaning. The "connection" and "coupling" mentioned in this application, unless otherwise specified, include direct and indirect connections (couplings).
[0028] Please refer to Figure 1 Some embodiments of the present application disclose a reagent product preparation functional island 100, which includes at least one storage device 20, and the storage device 20 is provided with a storage portion for placing at least one orifice plate. When the storage portion can hold more than two orifice plates to be used, the storage device 20 can meet the reserve of the required number of orifice plates under a certain working time. Both the empty orifice plates and the final prepared products can be placed in the storage device 20 for temporary storage. In actual use, the orifice plates in the preparation process can also be placed in the storage portion for temporary storage, such as the orifice plates that have not been sealed after liquid separation. When used, adaptive adjustments can be made according to needs.
[0029] Please refer to Figure 1, the reagent product preparation function island 100 disclosed in some embodiments also includes at least one liquid dispensing device 30 for dispensing reagents into the orifice plate. It should be noted that the working mode of the liquid dispensing device 30 can be automatic, manual, or partially manual and partially automatic. As long as the liquid dispensing device 30 can meet the needs of liquid dispensing at the workstation, this embodiment does not make specific limitations. For example, the liquid dispensing device 30 only has basic functions such as storing reagents, and it is necessary to manually dispense the reagents into the orifice plate; or the liquid dispensing device 30 has the function of automatic liquid dispensing, but it is necessary to manually operate the equipment to start and stop to control the start and stop of liquid dispensing; or the liquid dispensing device 30 can self-sensing whether the orifice plate is in place, and the start and stop and liquid dispensing are all automatic modes.
[0030] Please refer to Figure 1 , the reagent product preparation function island 100 disclosed in some embodiments also includes a film sealing device 40, which is used to encapsulate the well plate after the liquid dispensing device 30 dispenses the reagent into the well plate. Similarly, the working mode of the film sealing device 40 can be automatic, manual, or partially manual and partially automatic. As long as the film sealing device 40 can achieve the function of film sealing at this station, this embodiment does not make specific restrictions. For example, it is necessary to manually apply adhesive on the film, and manually apply pressure to make the film and the well plate fully bonded; for example, the film used is a product that can be used directly after tearing off, in this case, it is only necessary to manually tear off the smooth layer on the surface, and manually apply pressure to make the film and the well plate fully bonded; for example, the film sealing device 40 is a fully automatic device, and the function of hot pressing and sealing is achieved through various mechanisms.
[0031] In addition, the present application does not limit the type of the film sealing device 40. For example, in some embodiments, a film sealing device 40 for sealing aluminum film can be selected, and in other embodiments, a film sealing device 40 for sealing plastic film can also be selected.
[0032] Please refer to Figure 1 In some embodiments, the reagent product preparation functional island 100 disclosed further includes a transport device 10, and at least two of the storage device 20, the liquid dispensing device 30 and the sealing device 40 are located within the transport range of the transport device 10, so that the well plate can be transported between at least two of the storage device 20, the liquid dispensing device 30 and the sealing device 40 through the transport device 10.
[0033] Specifically, the transfer operation in the preparation process of the reagent product at least includes moving the well plate from the storage device 20 to the liquid separation device 30, transferring from the liquid separation device 30 to the film sealing device 40, and transferring from the film sealing device 40 to the storage device 20, and finally the product encapsulated with the reagent is also placed in the storage device 20. The well plate is transferred between at least two of the storage device 20, the liquid separation device 30 and the film sealing device 40 by the transfer device 10, that is, in the above three transfer operations, at least one transfer operation is automatically realized by the transfer device 10, which can at least reduce the time consumption of the corresponding transfer operation. Therefore, compared with the related art, the reagent product preparation function island 100 of the present application can reduce the workload of manual handling and transfer to a certain extent, which is conducive to improving the preparation efficiency of the product.
[0034] As described above, the preparation of reagent products requires labeling of the products to clarify the types of reagents in the products. In the above-mentioned reagent product preparation function island 100, in some embodiments, the labeling operation can be performed manually before placing the empty well plate to be used into the storage device 20, or in other embodiments, the labeling operation can also be performed after the well plate is packaged, thereby meeting the batch production requirements of the same reagent product.
[0035] In some embodiments, in order to further improve the preparation efficiency, the reagent product preparation function island 100 may also include a labeling device 50, which is used to paste labels on the orifice plate. The labeling device 50 is located within the transfer range of the transfer device 10, so that the transfer device 10 can transfer the orifice plate between at least one of the storage device 20, the liquid separation device 30 and the film sealing device 40 and the labeling device 50, and then before labeling, the orifice plate can be automatically placed at the labeling device 50 from the previous station by the transfer device 10, or after labeling, the orifice plate is automatically transferred from the labeling device 50 to the next station by the transfer device 10, so as to further reduce the time of manual loading and unloading and manual handling. In addition, the three operation processes of the labeling device 50, the liquid separation device 30, and the film sealing device 40 are all integrated in the reagent product preparation function island 100, so that the steps of reagent product production are more reasonable, and the preparation process can also meet actual needs, which is conducive to improving production efficiency.
[0036] It should be noted that the unlabeled well plates to be used are stored in the storage device 20. When only one reagent product is produced, labeling can be done before liquid separation, after liquid separation, or after film sealing. If the same batch of well plates in the storage device 20 are used to prepare the functional island 100 of the reagent product to finally obtain two or more reagent products, in order to avoid confusion, the well plates can be labeled before liquid separation in some embodiments.
[0037] Like the liquid dispensing device 30 and the film sealing device 40, the working mode of the labeling device 50 can be automatic, manual, or partially manual and partially automatic. As long as the labeling device 50 can realize the function of pasting labels at the workstation, this embodiment does not make specific limitations. For example, the labeling device 50 only has the basic function of storing untorn labels, and it is necessary to manually print the labels, tear the labels from the label paper, and then manually stick the labels on the side of the orifice plate; for example, the labeling device also has the function of automatically peeling off the labels, and at this time, it is only necessary to manually stick the labels to the side of the orifice plate; for example, the labeling device 50 can also integrate at least two functions of automatic barcode printing, automatic label peeling, automatic sensing of whether the orifice plate is in place, and automatic labeling. If the labeling device 50 has all of the above functions, it can be understood that each action of the labeling device 50 is a fully automatic mode, which can shorten the overall time of the labeling action, realize automated barcode compilation, management, label printing and other tasks, and is conducive to improving product preparation efficiency.
[0038] In some embodiments, in order to further improve efficiency, at least one of the liquid separation device 30 , the film sealing device 40 , and the labeling device 50 may be a fully automatic device.
[0039] In some embodiments, the transfer device 10 may include at least one transfer mechanism, which is a non-manipulator structure. For example, the transfer mechanism may be composed of a conveyor belt, a clamping component, a lifting component, etc. A transfer mechanism may be provided between two devices that require automated transfer to achieve automation of the corresponding transfer operation. Different devices may transfer materials between each other through an independent transfer mechanism, or may transfer materials between at least three devices through the same transfer mechanism. The number of transfer mechanisms may be increased or decreased according to actual needs.
[0040] In order to control the cost and improve the concentration of each component of the reagent product preparation function island 100, in some embodiments, please refer to Figure 1 The transfer device 10 can be a transfer robot, and the storage device 20, the labeling device 50, the liquid dispensing device 30 and the film sealing device 40 are all distributed in the transfer range of the transfer robot. At this time, the same transfer robot can be docked with the storage device 20, the labeling device 50, the liquid dispensing device 30 and the film sealing device 40 respectively in different postures, so as to achieve the effect of orifice plate transfer, automatic loading and unloading between the devices by the same transfer robot.
[0041] In some embodiments, the transfer robot includes a robot body and a clamp connected to the execution end of the robot body, and the clamp can be an electric clamp, a pneumatic clamp, or any feasible clamp structure in the relevant technology. In other embodiments, the transfer robot can also be other structures, such as a robot structure with a suction cup as a picking method.
[0042] In some embodiments, the storage device 20 may be a fixed rack structure, and the removal of the orifice plate and the placement of the final product are both directly achieved by the transfer device 10. In some embodiments, the storage device 20 may also have a temporary storage portion and a conveying mechanism for taking and placing the orifice plate. The operation of the orifice plate leaving the storage portion and the operation of placing the final product in the storage portion are both achieved by the conveying mechanism, so that the orifice plate can be transferred between the temporary storage portion and the storage portion. The transfer device 10 transfers the unused orifice plate on the temporary storage portion to the next station. The number of temporary storage portions can be selected according to demand. This embodiment does not limit the specific structure of the storage device 20.
[0043] In order to improve the efficiency of liquid separation, in some embodiments, the liquid separation device 30 includes a liquid separation component 31 and at least one liquid storage chamber 32 for storing reagents. The liquid separation component 31 is connected to the liquid storage chamber 32 and is used to inject the reagents in the liquid storage chamber 32 into the well plate. By reasonably configuring the number of well plates to be used and the amount of reagents that can be stored in the liquid storage chamber 32, the liquid separation device 30 can meet the corresponding preparation requirements without adding reagents during the process, thereby reducing time consumption.
[0044] In some embodiments, when there is only one liquid dispensing component 31, but there are more than two liquid storage chambers 32 and there are more than two types of reagents, the corresponding pipelines and other structures can be replaced when dispensing different reagents to avoid cross contamination between reagents.
[0045] In order to make the liquid separation device 30 meet the requirements of dispensing more than two reagents while improving the liquid separation efficiency, in some embodiments, the number of liquid separation components 31 is the same as the number of liquid storage chambers 32, and the liquid separation components 31 are connected to the liquid storage chambers 32 in a one-to-one correspondence, so that there is no problem of cross contamination between reagents, and there is no need to replace some structures, which can improve production efficiency. The number of liquid separation components 31 can be adjusted according to demand, and this embodiment does not limit it.
[0046] In some embodiments, the reagent product preparation function island 100 may further include a stirring device 60, which is provided with a stirring portion 61, and the stirring portion 61 is used to extend into the liquid storage cavity 32 and stir the reagent to ensure uniform and sufficient mixing of the reagent. The stirring device 60 may be any feasible structure in the relevant technology, and this embodiment is not limited thereto.
[0047] Please refer to Figure 1 and Figure 2In some embodiments, the reagent product preparation functional island 100 may further include a first base 70, on which the liquid separation device 30 and the film sealing device 40 are arranged. The first base 70 provides an installation platform for the liquid separation device 30 and the film sealing device 40, and can effectively shorten the distance between the liquid separation device 30 and the film sealing device 40, which is beneficial to shortening the time for transferring the well plate between the liquid separation device 30 and the film sealing device 40, so as to improve production efficiency.
[0048] Please refer to Figure 1 and Figure 3 In some embodiments, the reagent product preparation functional island 100 further includes a second base 80, and the transfer device 10 is disposed on the second base 80, and the second base 80 provides a mounting platform for the transfer device 10. The second base 80 is disposed between the first base 70 and the storage device 20, and the positions between the storage device 20, the liquid separation device 30 and the film sealing device 40 are reasonably arranged, which is conducive to reducing the distance between the well plate and the storage device 20, the liquid separation device 30 and the film sealing device 40, thereby shortening the time for the well plate to be transferred between the liquid separation device 30 and the film sealing device 40, so as to improve production efficiency.
[0049] Please refer to Figure 2 and Figure 3 In some embodiments, the first base 70 has a first running wheel assembly 71 and a first supporting leg assembly 72 at the bottom, and at least one of the first running wheel assembly 71 and the first supporting leg assembly 72 is a height-adjustable structure, so that the first base 70 switches between two states of contacting the ground through the first running wheel assembly 71 and contacting the bottom surface through the first supporting leg assembly 72; and / or, the second base 80 has a second running wheel assembly 81 and a second supporting leg assembly 82 at the bottom, and at least one of the second running wheel assembly 81 and the second supporting leg assembly 82 is a height-adjustable structure, so that the second base 80 switches between two states of contacting the ground through the second running wheel assembly 81 and contacting the bottom surface through the second supporting leg assembly 82. When the first running wheel assembly 71 contacts the ground and the first supporting leg assembly 72 is off the ground, the first base 70 can be pushed and walked on the ground by the first running wheel assembly 71. After the position of the first base 70 is adjusted to the right position, the position of the first base 70 can be fixed by making the first running wheel assembly 71 off the ground and the first supporting leg assembly 72 contact the ground. Similarly, under the action of the first walking wheel assembly 71 and the second supporting leg assembly 82, the second base 80 can have the function of being pushed along the ground to change the position and the function of fixing the position after determining the position.
[0050] In some embodiments, the first running wheel assembly 71 includes at least four first running wheels disposed at the four corners of the bottom of the first base 70, and the first support leg assembly 72 includes at least four first support legs disposed at the four corners of the bottom of the first base 70. The configuration of the second running wheel assembly 81 and the second support leg assembly 82 of the second base 80 can refer to the corresponding structure of the first base 70, and will not be repeated here.
[0051] In some embodiments, the first base 70 has a first inner cavity and a door body that closes the first inner cavity. The liquid separating device 30 and the film sealing device 40 are arranged on the top surface of the first base 70. The wiring harnesses of the liquid separating device 30 and the film sealing device 40 are arranged in the first inner cavity through the threading holes set on the top surface of the first base 70. The electrical structures used for control can all be arranged in the first inner cavity.
[0052] In some embodiments, the first base 70 may also have a light bar 73, which can be used for aesthetic lighting and can also be used to display the status of the reagent product preparation function island 100. For example, when the light is on, it means that preparation is in progress, and when the light is off, it means that the current preparation is completed.
[0053] In order to keep the positional relationship between the transfer device 10, the liquid separation device 30 and the sealing device 40 fixed, in some embodiments, the first base 70 and the second base 80 are detachably connected, so that the positions of the first base 70 and the second base 80 will not change due to position transfer, thereby ensuring that the transfer device 10 can maintain precise docking with the corresponding component device, effectively reducing the probability of failure.
[0054] In some embodiments, the side of the second base 80 close to the first base 70 may have a buffer block 83 for contacting the first base 70, which is used to prevent the first base 70 and the second base 80 from bumping against each other when moving or assembling and connecting, and plays a buffering and protective role. In some embodiments, the side of the second base 80 close to the first base 70 may also have a connecting block 84, which is used for guiding positioning and screw fixing when the first base 70 and the second base 80 are assembled and connected.
[0055] In some embodiments, in order to keep the positional relationship among the storage device 20, the first base 70 and the second base 80 relatively fixed, the first base 70, the second base 80 and the storage device 20 are arranged side by side, and the storage device 20 is connected and fixed to the side of the second base 80, thereby limiting the relative positions among the first base 70, the second base 80 and the storage device 20.
[0056] In some embodiments, the second base 80 has a second inner cavity and a door body that closes the second inner cavity. The labeling device 50 and the transfer device 10 are arranged on the top surface of the second base 80. The wiring harnesses of the labeling device 50 and the transfer device 10 are arranged in the second inner cavity through the threading holes arranged on the top surface of the second base 80. The electrical structures used for control can be arranged in the second inner cavity. The second base 80 can also be provided with a structure for dissipating heat for all structures in the second inner cavity, such as a cooling fan.
[0057] In some embodiments, in order to reduce weight and improve the structural strength of the second base 80 , a reinforcing bracket may be provided on one side of the second base 80 close to the storage device 20 .
[0058] In some embodiments, the reagent product preparation functional island 100 further includes an electrically connected human-machine interaction device 90 and a control device, and the control device is used to control at least the transport device 10. When there are automatic devices in the storage device 20, the labeling device 50, the liquid dispensing device 30 and the film sealing device 40, the corresponding automatic devices can be electrically connected to the control device to control the operation of the automatic devices through the control device.
[0059] The following takes the transfer device 10 as a transfer robot, and the storage device 20, labeling device 50, liquid separation device 30 and film sealing device 40 as automated equipment as an example to introduce the working principle of the reagent product preparation functional island 100 provided in some embodiments of the present application.
[0060] The transfer range of the transfer robot is equipped with a labeling device 50, a sealing device 40, two storage devices 20 and two liquid dispensing devices 30. First, fill the storage device 20 with a new 96-well plate, and then add the reagent to be dispensed into the liquid storage chamber 32 of the liquid dispensing device 30. The human-machine interaction device 90 is operated to initialize the equipment, and then the process is started. The reagent product preparation function island 100 automatically prepares the reagent product according to the sequence of "taking materials-labeling-liquid dispensing-sealing-storage". The preparation process of a single well plate is as follows:
[0061] 1. The transfer robot transfers the well plate from the storage device 20 to the tray of the labeling device 50. The labeling device 50 performs the labeling action and attaches the label to the side of the 96-well plate. Automated labeling can improve the labeling quality, eliminate the risk of human labeling errors, and reduce work intensity.
[0062] 2. The transfer robot carries the labeled 96-well plate to the tray of the liquid dispensing device 30 , and the liquid dispensing device 30 performs an automatic liquid dispensing operation to add the reagent in the liquid storage chamber 32 into the 96-well plate.
[0063] 3. The transfer robot moves the 96-well plate after separation to the tray of the film sealing device 40. The film sealing device 40 performs an automatic film sealing action to seal a layer of aluminum film on the top of the 96-well plate. The film is automatically sealed by the film sealing device 40, and there is no need for personnel to manually load and unload the plate, thereby reducing work intensity.
[0064] 4. The transfer robot moves the products on the tray of the film sealing device 40 to the storage portion of the storage device 20 .
[0065] Compared with the traditional preparation mode that relies heavily on manual operation, the reagent product preparation function island 100 of the present application integrates the functions of automatic labeling, automatic liquid separation, automatic film sealing and product temporary storage, the quality of the product can be effectively guaranteed, and the transfer operation in the production process is completed by the transfer manipulator, which can complete the medium and high throughput unattended reagent product preparation of the fully automatic production line, can reduce the manual workload, reduce the work intensity of personnel, and is conducive to improving the preparation efficiency. The reagent product preparation function island 100 can also be adapted to the packaging of various different reagents, such as gene detection reagents, etc., and can also be used for normal temperature reagent packaging of products such as colorectal cancer, Meta, HPV, etc.
[0066] The above specific examples are used to illustrate the present invention, which are only used to help understand the present invention and are not intended to limit the present invention. For those skilled in the art of the present invention, some simple deductions, deformations or substitutions can be made based on the idea of the present invention.
Claims
1. A reagent product preparation functional island, characterized in that: include: at least one storage device having a storage portion for placing the orifice plate; at least one dispensing device for dispensing reagents into the well plate; A sealing device, used for sealing the well plate after the reagent is dispensed into the well plate; and a transfer device, wherein at least two of the storage device, the liquid dispensing device and the film sealing device are located within a transfer range of the transfer device, so that the transfer device can transfer the well plate between at least two of the storage device, the liquid dispensing device and the film sealing device.
2. The reagent product preparation functional island according to claim 1, characterized in that: The reagent product preparation functional island also includes a labeling device for attaching a label to the well plate; The labeling device is located within the transport range of the transport device, and the transport device can transport the well plate between the labeling device and at least one of the storage device, the liquid dispensing device and the film sealing device.
3. The reagent product preparation functional island according to claim 2, characterized in that: The transfer device is a transfer robot, and the storage device, the labeling device, the liquid separation device and the film sealing device are all distributed within the transfer range of the transfer robot, and the orifice plate transfer between the devices is achieved by the same transfer robot.
4. The reagent product preparation functional island according to claim 1, characterized in that: The liquid dispensing device comprises a liquid dispensing component and at least one liquid storage cavity for storing a reagent. The liquid dispensing component is in communication with the liquid storage cavity and is used to inject the reagent in the liquid storage cavity into the orifice plate.
5. The reagent product preparation functional island according to claim 4, characterized in that: The number of the liquid separation components is the same as the number of the liquid storage chambers, and the liquid separation components are connected to the liquid storage chambers in a one-to-one correspondence.
6. The reagent product preparation functional island according to claim 4, characterized in that: The reagent product preparation functional island further comprises a stirring device, wherein the stirring device is provided with a stirring portion, and the stirring portion is used to extend into the liquid storage cavity and stir the reagent.
7. The reagent product preparation functional island according to any one of claims 1 to 6, characterized in that: The reagent product preparation functional island further comprises a first base, and the liquid separation device and the film sealing device are arranged on the first base.
8. The reagent product preparation functional island according to claim 7, characterized in that: The reagent product preparation functional island also includes a second base, the transfer device is arranged on the second base, and the second base is arranged between the first base and the storage device.
9. The reagent product preparation functional island according to claim 8, characterized in that: The bottom of the first base has a first running wheel assembly and a first supporting leg assembly, and at least one of the first running wheel assembly and the first supporting leg assembly is a height-adjustable structure, so that the first base can be switched between two states of contacting the ground through the first running wheel assembly and contacting the bottom surface through the first supporting leg assembly; And / or, a second walking wheel assembly and a second supporting leg assembly are provided at the bottom of the second base, and at least one of the second walking wheel assembly and the second supporting leg assembly is a height-adjustable structure so that the second base can switch between two states of contacting the ground through the second walking wheel assembly and contacting the bottom surface through the second supporting leg assembly.
10. The reagent product preparation functional island according to any one of claims 1 to 5, characterized in that: The reagent product preparation functional island also includes an electrically connected human-machine interaction device and a control device, and the control device is used to at least control the transport device.