Cell bioreactor

Abstract

The utility model relates to the technical field of cell biological culture, in particular to a cell bioreactor which comprises a reaction tank, a cover plate is fixed at the top end of the reaction tank, a box body and a guide pipe are fixed at the top end of the cover plate, a notch and a support are arranged on one side of the box body, limiting bolts are arranged on two sides of the box body, a motor is fixed on the support, and the guide pipe is fixed on the motor. A connecting rod is arranged on one side of the motor, the end, away from the motor, of the connecting rod penetrates through the box and is connected with a hand wheel, a vertical rod is arranged in the reaction tank, a first bevel gear and a plurality of cross rods are fixed to the vertical rod, and second bevel gears matched with the first bevel gear are fixed to the end, away from the hand wheel, of the connecting rod and an output shaft of the motor; the hand wheel is shaken, the hand wheel drives the connecting rod to rotate, the second bevel gear rotates along with the hand wheel, the second bevel gear rotates to drive the first bevel gear to rotate, the vertical rod and the cross rod rotate, the two limiting bolts are unscrewed, the support is pulled to move away from the connecting rod, then the support and the motor can be dismounted together for maintenance, and stirring work is not affected.

Description

Technical Field

[0001] The utility model relates to the technical field of cell biological culture, in particular to a cell bioreactor. Background Art

[0002] Cell culture refers to a method of simulating the in vivo environment (sterility, suitable temperature, pH and certain nutritional conditions, etc.) in vitro to enable cells to survive, grow, reproduce and maintain their main structures and functions. During cell culture, cells are generally placed in a reactor filled with culture medium. The motor on the reactor drives the stirring rod to rotate to achieve mixing of cells and culture medium to facilitate cell proliferation. When the motor needs to be removed for maintenance or fails, the stirring work needs to be stopped, which affects the mixing of cells and culture medium. Therefore, a cell bioreactor is proposed to ensure the normal stirring work. Utility Model Content

[0003] In view of the problems in the prior art, the utility model provides a cell bioreactor.

[0004] The utility model solves the technical problem by adopting a technical solution to provide a cell bioreactor, comprising a reaction tank, a valve is fixed at the bottom end of the reaction tank, a cover plate is fixed at the top end of the reaction tank, a box body and a conduit are fixed at the top end of the cover plate, a protective cover is threadedly connected at the top end of the conduit, a notch and a support are provided on one side of the box body, limiting bolts are provided on both sides of the box body, screw holes adapted to the limiting bolts are provided on the support and both sides of the box body, a motor is fixed on the support, a connecting rod is provided on one side of the motor, an end of the connecting rod away from the motor penetrates the box body and is connected to a hand wheel, a vertical rod is provided in the reaction tank, the top end of the vertical rod penetrates the cover plate and extends into the box body, a first bevel gear and a plurality of cross rods are fixed on the vertical rod, the plurality of cross rods are all located in the reaction tank, a second bevel gear adapted to the first bevel gear is fixed on the end of the connecting rod away from the hand wheel and the output shaft of the motor, two bearing seats are fixed in the box body, an inner ring of one bearing seat is connected to the vertical rod, and an inner ring of the other bearing seat is connected to the connecting rod.

[0005] By adopting the above technical solution, the culture medium is introduced into the reaction tank through the catheter, and then cells are added to the reaction tank. The output shaft of the motor drives the second bevel gear to rotate, and the first bevel gear, the vertical rod and the horizontal rod rotate accordingly to achieve mixing of the cells and the culture medium. When the motor needs to be removed for maintenance or the motor fails, the hand wheel is shaken, and the hand wheel drives the connecting rod to rotate. When the connecting rod rotates, the second bevel gear at the end of the connecting rod rotates accordingly. When the second bevel gear rotates, it drives the first bevel gear to rotate, and the vertical rod and the horizontal rod rotate. The two limit bolts are loosened and the support is pulled away from the connecting rod to move, so that the support together with the motor can be removed for maintenance without affecting the stirring work.

[0006] Specifically, a handle is fixed on a side of the support away from the motor.

[0007] By adopting the above technical solution, the support can be conveniently taken and placed by holding the handle.

[0008] Specifically, ventilation holes are provided on both sides of the box body, and dustproof nets are provided in the two ventilation holes.

[0009] By adopting the above technical solution, the provision of the vents and the dustproof net is conducive to the dissipation of heat inside the box.

[0010] Specifically, the reaction tank is provided with an observation window, and glass is provided inside the observation window.

[0011] By adopting the above technical solution, the situation inside the reaction tank can be easily observed through the observation window and the glass.

[0012] Specifically, a plurality of legs are fixed to the bottom end of the reaction tank.

[0013] Beneficial effects of the utility model:

[0014] (1) The cell bioreactor described in the utility model introduces culture medium into a reaction tank through a catheter, and then adds cells to the reaction tank. The output shaft of the motor drives the second bevel gear to rotate, and the first bevel gear, the vertical rod and the horizontal rod rotate accordingly to achieve mixing of the cells and the culture medium. When the motor needs to be removed for maintenance or the motor fails, the hand wheel is shaken, and the hand wheel drives the connecting rod to rotate. When the connecting rod rotates, the second bevel gear at the end of the connecting rod rotates accordingly. When the second bevel gear rotates, it drives the first bevel gear to rotate, and the vertical rod and the horizontal rod rotate. The two limit bolts are loosened and the support is pulled away from the connecting rod to move, so that the support together with the motor can be removed for maintenance without affecting the stirring work.

[0015] (2) The cell bioreactor described in the utility model has a handle that facilitates the taking and placing of the support, and the observation window and glass facilitate the observation of the internal conditions of the reaction tank. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] The utility model is further described below in conjunction with the accompanying drawings and embodiments.

[0017] Figure 1 It is a structural schematic diagram of the utility model;

[0018] Figure 2 For the utility model Figure 1 A magnified view of the structure at center A;

[0019] Figure 3 It is a cross-sectional view of the box body of the present utility model.

[0020] In the figure: 1. reaction tank; 2. cover plate; 3. support; 4. box body; 5. hand wheel; 6. guide tube; 7. protective cover; 8. support leg; 9. valve; 10. glass; 11. limit bolt; 12. handle; 13. motor; 14. vertical rod; 15. horizontal rod; 16. bearing seat; 17. first bevel gear; 18. second bevel gear; 19. connecting rod. DETAILED DESCRIPTION

[0021] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further described below in conjunction with specific implementation methods.

[0022] In order to ensure the normal stirring operation when the motor 13 is maintained or fails, as an embodiment of the present utility model, Figure 1 , Figure 2 , Figure 3 As shown, a cell bioreactor described in the utility model comprises a reaction tank 1, a valve 9 is welded and fixed at the bottom end of the reaction tank 1, a cover plate 2 is fixed to the top of the reaction tank 1 by bolts, a box body 4 and a conduit 6 are welded and fixed to the top end of the cover plate 2, a protective cover 7 is threadedly connected to the top end of the conduit 6, a notch and a support 3 are provided on one side of the box body 4, limiting bolts 11 are provided on both sides of the support 3 and the box body 4, screw holes adapted to the limiting bolts 11 are opened on both sides of the support 3 and the box body 4, a motor 13 is fixed to the support 3 by bolts, a connecting rod 19 is provided on one side of the motor 13, and the connecting rod 19 is away from the motor One end of 13 passes through the box body 4 and is welded to a handwheel 5. A vertical rod 14 is provided in the reaction tank 1. The top end of the vertical rod 14 passes through the cover plate 2 and extends into the box body 4. A first bevel gear 17 and a plurality of cross bars 15 are welded and fixed on the vertical rod 14. The plurality of cross bars 15 are all located in the reaction tank 1. A second bevel gear 18 adapted to the first bevel gear 17 is welded and fixed on one end of the connecting rod 19 away from the handwheel 5 and on the output shaft of the motor 13. Two bearing seats 16 are fixed in the box body 4 by bolts, wherein the inner ring of one bearing seat 16 is welded to the vertical rod 14, and the inner ring of the other bearing seat 16 is welded to the connecting rod 19.

[0023] When in use, the culture medium is introduced into the reaction tank 1 through the catheter 6, and then cells are added to the reaction tank 1. The output shaft of the motor 13 drives the second bevel gear 18 to rotate, and the first bevel gear 17, the vertical rod 14 and the horizontal rod 15 rotate accordingly to achieve mixing of the cells and the culture medium. When the motor 13 needs to be removed for maintenance or the motor 13 fails, the handwheel 5 is shaken, and the handwheel 5 drives the connecting rod 19 to rotate. When the connecting rod 19 rotates, the second bevel gear 18 at the end of the connecting rod 19 rotates accordingly. When the second bevel gear 18 rotates, it drives the first bevel gear 17 to rotate, and the vertical rod 14 and the horizontal rod 15 rotate. The two limit bolts 11 are loosened and the support 3 is pulled away from the connecting rod 19 to remove the support 3 together with the motor 13 for maintenance without affecting the stirring work.

[0024] In order to facilitate the placement and removal of the support 3, for example, Figure 2 As shown, a handle 12 is welded and fixed to the side of the support 3 away from the motor 13 .

[0025] In order to facilitate the dissipation of heat inside the box 4, for example, Figure 1 As shown, ventilation holes are provided on both sides of the box body 4 , dustproof nets are provided in the two ventilation holes, and the two dustproof nets are welded to the box body 4 .

[0026] In order to facilitate observation of the situation inside the reaction tank 1, for example, Figure 1 As shown, the reaction tank 1 is provided with an observation window, and a glass 10 is provided in the observation window. The glass 10 is connected to the reaction tank 1 through an adhesive.

[0027] A plurality of legs 8 are welded and fixed to the bottom end of the reaction tank 1 .

[0028] When the utility model is used, the culture fluid is introduced into the reaction tank 1 through the conduit 6, and then cells are added to the reaction tank 1. The output shaft of the motor 13 drives the second bevel gear 18 to rotate, and the first bevel gear 17, the vertical rod 14 and the horizontal rod 15 rotate accordingly, so as to achieve mixing of the cells and the culture fluid.

[0029] When the motor 13 needs to be removed for maintenance or the motor 13 fails, the hand wheel 5 is shaken, and the hand wheel 5 drives the connecting rod 19 to rotate. When the connecting rod 19 rotates, the second bevel gear 18 at the end of the connecting rod 19 rotates accordingly. When the second bevel gear 18 rotates, it drives the first bevel gear 17 to rotate, and the vertical rod 14 and the horizontal rod 15 rotate. The two limit bolts 11 are loosened and the support 3 is pulled away from the connecting rod 19. The support 3 and the motor 13 can be removed for maintenance together without affecting the mixing work.

[0030] The above shows and describes the basic principles, main features and advantages of the utility model. Those skilled in the art should understand that the utility model is not limited by the above embodiments. The above embodiments and the description in the specification are only to illustrate the principles of the utility model. Without departing from the spirit and scope of the utility model, the utility model will have various changes and improvements, and these changes and improvements fall within the scope of protection claimed by the utility model. The scope of protection claimed by the utility model is defined by the attached claims and their equivalents. The contents not described in detail in the utility model belong to the prior art known to those skilled in the art.

Claims

1. A cell bioreactor, characterized in that: The invention comprises a reaction tank (1), wherein a valve (9) is fixed at the bottom end of the reaction tank (1), a cover plate (2) is fixed at the top end of the reaction tank (1), a box body (4) and a conduit (6) are fixed at the top end of the cover plate (2), a protective cover (7) is threadedly connected to the top end of the conduit (6), a notch and a support (3) are provided on one side of the box body (4), limiting bolts (11) are provided on both sides of the support (3) and the box body (4), screw holes adapted to the limiting bolts (11) are provided on both sides of the support (3) and the box body (4), a motor (13) is fixed on the support (3), a connecting rod (19) is provided on one side of the motor (13), and the end of the connecting rod (19) away from the motor (13) passes through the box body (4) and connected to a hand wheel (5), a vertical rod (14) is provided in the reaction tank (1), the top end of the vertical rod (14) passes through the cover plate (2) and extends into the box body (4), a first bevel gear (17) and a plurality of cross rods (15) are fixed on the vertical rod (14), and the plurality of cross rods (15) are all located in the reaction tank (1), a second bevel gear (18) adapted to the first bevel gear (17) is fixed on the end of the connecting rod (19) away from the hand wheel (5) and the output shaft of the motor (13), two bearing seats (16) are fixed in the box body (4), the inner ring of one bearing seat (16) is connected to the vertical rod (14), and the inner ring of the other bearing seat (16) is connected to the connecting rod (19).

2. A cell bioreactor according to claim 1, characterized in that: A handle (12) is fixed to the side of the support (3) away from the motor (13).

3. A cell bioreactor according to claim 1, characterized in that: Both sides of the box body (4) are provided with ventilation holes, and dustproof nets are provided in the two ventilation holes.

4. A cell bioreactor according to claim 1, characterized in that: The reaction tank (1) is provided with an observation window, and glass (10) is provided in the observation window.

5. A cell bioreactor according to claim 1, characterized in that: A plurality of supporting legs (8) are fixed to the bottom end of the reaction tank (1).

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