Pipetting device

Abstract

The utility model relates to a pipetting device which comprises a machine table, a test tube rack for placing a test tube and a pipetting mechanism, the pipetting mechanism can move up and down relative to the test tube rack, the pipetting mechanism comprises a mounting rack, a plurality of pipetting assemblies are arranged on the mounting rack, each pipetting assembly comprises a pipetting sleeve and a piston rod, and the piston rod is arranged on the pipetting sleeve. The pipetting sleeve is rotationally arranged on the mounting frame, a gear is arranged at the upper end of the pipetting sleeve, and a rotating assembly for driving the pipetting sleeve to rotate through the gear and a driving assembly for driving the piston rod to move up and down along the inner wall of the pipetting sleeve are arranged on the mounting frame. According to the technical scheme, one driving assembly drives a plurality of piston rods to move up and down to achieve liquid taking, one rotating assembly drives a plurality of pipetting sleeves to rotate, liquid stirring and mixing are achieved, whole-process automatic setting is achieved, the liquid taking precision and efficiency are greatly improved, and the labor cost is reduced.

Description

Technical Field

[0001] The utility model relates to the technical field of biomedical equipment, in particular to a liquid transfer device. Background Art

[0002] Liquid handling devices are widely used in biochemical research laboratories, hospitals and pharmaceutical companies. They can be used for sample pretreatment, sample purification and amplification, sample dilution and concentration, sample preparation and other sample handling operations as well as liquid experimental testing. They generally include a pipette sleeve, a piston rod and a nozzle. When aspirating liquid, as the piston rod in the pipette sleeve is pulled out, the liquid is sucked into the pump chamber under the action of the negative pressure in the pipette sleeve; similarly, by pushing the piston rod, liquid of the same volume as the space through which the piston rod moves can be pushed out.

[0003] Existing pipetting devices rely on gas compression, and their accuracy is affected by the environment, especially temperature and user skills. In addition, existing pipetting devices have a single function, and the mixing after pipetting is mostly done manually, which is inefficient. Utility Model Content

[0004] In summary, in order to overcome the deficiencies of the prior art, the utility model provides a liquid transfer device.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a pipetting device, comprising a machine, a test tube rack for placing test tubes and a pipetting mechanism, wherein the pipetting mechanism can move up and down relative to the test tube rack, the pipetting mechanism comprises a mounting frame, a plurality of pipetting components are arranged on the mounting frame, the pipetting components comprise a pipetting sleeve and a piston rod, the pipetting sleeve is rotatably arranged on the mounting frame, a gear is arranged on the upper end of the pipetting sleeve, the mounting frame is provided with a rotating component that drives the pipetting sleeve to rotate through the gear and a driving component that drives the piston rod to move up and down along the inner wall of the pipetting sleeve.

[0006] By adopting the above technical solution, a driving component drives multiple piston rods to move up and down to achieve liquid extraction, and a rotating component drives multiple pipetting sleeves to rotate to achieve stirring and mixing of liquids. The whole process is automated, which greatly improves the accuracy and efficiency of liquid extraction and reduces labor costs.

[0007] The utility model is further configured as follows: the rotating assembly includes a servo motor and a driving shaft, a driving wheel is arranged on the driving shaft, the gear includes an upper gear and a lower gear, the lower gears are connected by a synchronous belt, and the driving wheel is connected to one of the upper gears by a synchronous belt.

[0008] By adopting the above technical solution, the driving wheel is controlled by a servo motor, and the synchronous belt and gear cooperate to rotate, so that the stirring speed can be controlled, the mixing effect is improved, and the automation setting is conducive.

[0009] The utility model is further configured as follows: the driving assembly includes a driving motor and a pressure rod, the mounting frame is provided with sliding grooves at both ends of the pressure rod corresponding to the pressure rod, the two ends of the pressure rod are provided with sliding parts adapted to the sliding grooves, and the driving motor drives the piston rod to move downward along the sliding groove through the pressure rod.

[0010] By adopting the above technical solution, the driving motor presses down along the sliding groove through the pressure rod, driving multiple piston rods to move down a certain active stroke at the same time. By setting the driving motor, the volume of the inserted liquid can be controlled, greatly improving the accuracy of pipetting, especially the accuracy when taking a small amount of liquid.

[0011] The utility model is further provided with: an operating part is provided at the upper end of the piston rod, and a return spring is provided between the operating part and the gear.

[0012] By adopting the above technical solution, the driving motor controls the movable stroke of the pressure rod, and the return spring gives the operating part an upward push force, ensuring that the relative displacement of the pipette sleeve and the piston rod is more stable (because the pipette sleeve is rotatably connected to the mounting frame). At the same time, the operating part and the pressure rod move through abutment rather than fixed movement, which facilitates the adjustment of the spacing of the pipette components.

[0013] The utility model is further configured as follows: the mounting frame is provided with mounting clamps on the front and rear sides corresponding to the pipetting sleeve, the mounting clamps are provided with mounting blocks matched with the number of pipetting components and sliding slots for sliding connection with the mounting blocks, the mounting block is provided with an arc-shaped recess matched with the outer diameter of the pipetting sleeve on one side corresponding to the pipetting sleeve, and a mounting portion matched with the sliding slot is provided on the other side, the sliding slot is provided on one side of the mounting clamp corresponding to the mounting block and is open at both ends, and a long strip-shaped mounting through hole is provided on the other side of the mounting clamp corresponding to the position of the sliding slot, and the mounting through hole is provided with a fastener for positioning the mounting portion.

[0014] By adopting the above technical solution, the spacing of the pipetting components can be adjusted according to needs by moving the position of the mounting block, and the mounting block and the mounting clamp are relatively fixed by tightening the fasteners, which has a simple structure and is easy to operate.

[0015] The utility model is further configured as follows: a limiting ring portion is arranged below the gear at the upper end of the pipetting sleeve, the diameter of the limiting ring portion is larger than the outer diameter of the pipetting sleeve, and the limiting ring portion is arranged above the mounting block.

[0016] By adopting the above technical solution, the limiting ring part limits the height position of the pipetting sleeve, and a gap can be set between the mounting clamping plate and the pipetting sleeve to reduce the friction force of the rotation of the pipetting sleeve.

[0017] The utility model is further provided that: the mounting clamping plate comprises a fixed clamping plate and a movable clamping plate, the fixed clamping plate is detachably connected to the mounting frame, the movable clamping plate is connected to the electric push rod, and the electric push rod is arranged on a side of the mounting frame opposite to the movable clamping plate.

[0018] By adopting the above technical solution, the electric push rod controls the distance between the movable clamping plate and the fixed clamping plate, which facilitates the disassembly and adjustment of the position of the installation block.

[0019] The utility model is further arranged that: the mounting frame is arranged on the three-axis moving mechanism, and the test tube rack is arranged on the conveying mechanism.

[0020] By adopting the above technical solution, the fully automatic setting is further strengthened, making the operation of the pipetting mechanism faster and more convenient, and improving work efficiency.

[0021] The specific implementation of the utility model is described below in conjunction with the drawings and embodiments. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 It is a three-dimensional diagram of an embodiment of the utility model;

[0023] Figure 2 It is a rear view of the local structure of the embodiment of the utility model;

[0024] Figure 3 It is a side view of the local structure of an embodiment of the utility model;

[0025] Figure 4 for Figure 3 A magnified view of part A;

[0026] Figure numerals: 1. machine, 2. test tube rack, 3. pipetting mechanism, 31. mounting frame, 311. sliding groove, 32. pipetting assembly, 321. pipetting sleeve, 3211. gear, 3212. limiting ring, 322. piston rod, 3221. operating part, 323. reset spring, 33. rotating assembly, 331. servo motor, 332. driving shaft, 333. driving wheel, 34. driving assembly, 341. driving motor, 342. pressure rod, 3421. sliding part, 4. mounting splint, 41. sliding slot, 42. mounting through hole, 43. fixed splint, 44. movable splint, 45. electric push rod, 5. mounting block, 51. arc-shaped recess, 52. mounting part, 6. three-axis moving mechanism, 7. transmission mechanism. DETAILED DESCRIPTION

[0027] This specific embodiment is merely an explanation of the present invention and is not a limitation of the present invention. After reading this specification, those skilled in the art may make modifications to the present embodiment without any creative contribution as needed. However, as long as the modifications are within the scope of the claims of the present invention, they are protected by the patent law.

[0028] See attached Figure 1-4 A pipetting device disclosed in this embodiment includes a machine platform 1, a test tube rack 2 for placing test tubes, and a pipetting mechanism 3. The pipetting mechanism 3 can move up and down relative to the test tube rack 2. The pipetting mechanism 3 includes a mounting frame 31. A plurality of pipetting components 32 are arranged on the mounting frame 31. The pipetting components 32 include a pipetting sleeve 321 and a piston rod 322. The pipetting sleeve 321 is rotatably arranged on the mounting frame 31. A gear 3211 is arranged on the upper end of the pipetting sleeve 321. A rotating component 33 that drives the pipetting sleeve 321 to rotate through the gear 3211 and a driving component 34 that drives the piston rod 322 to move up and down along the inner wall of the pipetting sleeve 321 are arranged on the mounting frame 31.

[0029] This embodiment further configures: the rotating assembly 33 includes a servo motor 331 and a driving shaft 332, a driving wheel 333 is provided on the driving shaft 332, the gear 3211 includes an upper gear and a lower gear, the lower gears are connected by a synchronous belt, and the driving wheel 333 is connected to one of the upper gears by a synchronous belt.

[0030] This embodiment is further configured as follows: the driving assembly 34 includes a driving motor 341 and a pressure rod 342, the mounting frame 31 is provided with sliding grooves 311 at both ends of the pressure rod 342, and the pressure rod 342 is provided with sliding parts 3421 adapted to the sliding grooves 311 at both ends, and the driving motor 341 drives the piston rod 322 to move downward along the sliding groove 311 through the pressure rod 342.

[0031] This embodiment is further configured as follows: an operating portion 3221 is provided at the upper end of the piston rod 322 , and a return spring 323 is provided between the operating portion 3221 and the gear 3211 .

[0032] This embodiment is further configured as follows: the mounting frame 31 is provided with mounting plates 4 on the front and rear sides corresponding to the pipetting sleeve 321; the mounting plates 4 are provided with mounting blocks 5 matched with the number of pipetting components 32 and sliding slots 41 for sliding connection with the mounting blocks 5; the mounting block 5 is provided with an arc-shaped recess 51 matched with the outer diameter of the pipetting sleeve 321 on one side corresponding to the pipetting sleeve 321, and a mounting portion 52 matched with the sliding slot 41 is provided on the other side; the sliding slot 41 is provided on one side of the mounting plate 4 corresponding to the mounting block 5 and is open at both ends; the other side of the mounting plate 4 is provided with a long strip mounting through hole 42 corresponding to the position of the sliding slot 41; the mounting through hole 42 is provided with a fastener for positioning the mounting portion 52.

[0033] This embodiment is further configured as follows: a limit ring portion 3212 is provided below the gear 3211 at the upper end of the pipetting sleeve 321 , the diameter of the limit ring portion 3212 is larger than the outer diameter of the pipetting sleeve 321 , and the limit ring portion 3212 is provided above the mounting block 5 .

[0034] This embodiment further provides: the mounting clamp plate 4 includes a fixed clamp plate 43 and a movable clamp plate 44, the fixed clamp plate 43 is detachably connected to the mounting frame 31, the movable clamp plate 44 is connected to the electric push rod 45, and the electric push rod 45 is arranged on the side of the mounting frame 31 opposite to the movable clamp plate 44.

[0035] This embodiment further configures: the mounting frame 31 is disposed on the three-axis moving mechanism 6 , and the test tube rack 2 is disposed on the conveying mechanism 7 .

[0036] In the technical solution of the utility model, the mounting block 5 is slidably arranged, so the length of the synchronous belt between the lower gears needs to be adjusted, and the adjustment of the synchronous belt can be achieved by setting a tensioning wheel and an adjusting wheel. The tensioning wheel is arranged on the outside of the synchronous belt, and the adjusting wheel is arranged inside the synchronous belt and coaxially with the movable shaft. The movable shaft is movably connected to the mounting frame (it can be driven by a driving mechanism, or the mounting frame is provided with a sliding groove, and the position of the movable shaft is manually adjusted, and it is detachably connected to the mounting frame through fasteners).

[0037] Since the three-axis moving mechanism is a well-known technical common sense in automation equipment, it will not be elaborated in detail.

[0038] The above-mentioned “between” does not only refer to directions and positions, but also includes the meaning of the interaction between different parts. The above-mentioned “upper and lower” are only relative descriptions for the convenience of description and understanding, and other possibilities are not excluded.

[0039] Although the terms machine 1, test tube rack 2, liquid transfer mechanism 3, mounting frame 31, sliding groove 311, liquid transfer assembly 32, liquid transfer sleeve 321, gear 3211, limit ring 3212, piston rod 322, operating part 3221, reset spring 323, rotating assembly 33, servo motor 331, drive shaft 332, drive wheel 333, drive assembly 34, drive motor 341, pressure rod 342, sliding part 3421, mounting clamp 4, sliding slot 41, mounting through hole 42, fixed clamp 43, movable clamp 44, electric push rod 45, mounting block 5, arc-shaped recess 51, mounting part 52, three-axis moving mechanism 6, and transmission mechanism 7 are used more frequently in this article, the possibility of using other terms is not excluded. The use of these terms is only for the purpose of more conveniently describing and explaining the essence of the utility model; interpreting them as any additional restrictions is contrary to the spirit of the utility model.

Claims

1. A liquid transfer device, characterized in that: The invention comprises a machine, a test tube rack for placing test tubes and a pipetting mechanism, wherein the pipetting mechanism can move up and down relative to the test tube rack, the pipetting mechanism comprises a mounting frame, a plurality of pipetting components are arranged on the mounting frame, the pipetting components comprise a pipetting sleeve and a piston rod, the pipetting sleeve is rotatably arranged on the mounting frame, a gear is arranged on the upper end of the pipetting sleeve, a rotating component which drives the pipetting sleeve to rotate through the gear and a driving component which drives the piston rod to move up and down along the inner wall of the pipetting sleeve are arranged on the mounting frame.

2. A liquid transfer device according to claim 1, characterized in that: The rotating assembly includes a servo motor and a driving shaft, a driving wheel is arranged on the driving shaft, the gear includes an upper gear and a lower gear, the lower gears are connected by a synchronous belt, and the driving wheel is connected to one of the upper gears by a synchronous belt.

3. A liquid transfer device according to claim 1, characterized in that: The driving assembly includes a driving motor and a pressure rod. The mounting frame is provided with sliding grooves at both ends of the pressure rod. The pressure rod is provided with sliding parts adapted to the sliding grooves at both ends. The driving motor drives the piston rod to move downward along the sliding grooves through the pressure rod.

4. A liquid transfer device according to claim 3, characterized in that: An operating part is arranged at the upper end of the piston rod, and a return spring is arranged between the operating part and the gear.

5. A liquid transfer device according to claim 1, characterized in that: The mounting frame is provided with mounting clamps on the front and rear sides corresponding to the pipetting sleeve, the mounting clamps are provided with mounting blocks matched with the number of pipetting components and sliding slots for sliding connection with the mounting blocks, one side of the mounting block corresponding to the pipetting sleeve is provided with an arc-shaped recess matched with the outer diameter of the pipetting sleeve, and the other side is provided with a mounting portion matched with the sliding slot, the sliding slot is provided on one side of the mounting clamp corresponding to the mounting block and is open at both ends, and the other side of the mounting clamp is provided with a long strip of mounting through holes corresponding to the position of the sliding slot, and the mounting through holes are provided with fasteners for positioning the mounting portion.

6. A liquid transfer device according to claim 5, characterized in that: A limiting ring portion is arranged below the gear at the upper end of the pipetting sleeve, the diameter of the limiting ring portion is larger than the outer diameter of the pipetting sleeve, and the limiting ring portion is arranged above the mounting block.

7. A liquid transfer device according to claim 5, characterized in that: The mounting clamping plate comprises a fixed clamping plate and a movable clamping plate, wherein the fixed clamping plate is detachably connected to the mounting frame, and the movable clamping plate is connected to an electric push rod, and the electric push rod is arranged on a side of the mounting frame opposite to the movable clamping plate.

8. A liquid transfer device according to claim 7, characterized in that: The mounting frame is arranged on a three-axis moving mechanism, and the test tube rack is arranged on a conveying mechanism.

Images