Selenium-rich protein enrichment device
By designing a selenium-enriched protein enrichment device including a height adjustment component, an adsorption tube, a filter plate and an adsorption layer, the problems of complex operation, time-consuming and low enrichment efficiency of traditional protein purification methods are solved, and an efficient and simplified protein enrichment process is achieved.
Patent Information
- Application Number
- CN202421897606.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-08-07
- Publication Date
- 2025-05-16
- Estimated Expiration
- 2034-08-07
AI Technical Summary
Traditional protein purification methods are complex, time-consuming, and difficult to achieve efficient enrichment effects. Especially when processing large or low-concentration samples, the filter plate is prone to clogging and needs to be disassembled and cleaned.
A selenium-enriched protein enrichment device is designed, including a height adjustment assembly, an adsorption tube, a filter plate and an adsorption layer. The height adjustment and rapid replacement of the filter plate are achieved through threaded connections and spring devices, and the ion exchange resin is used as the adsorption layer material to achieve efficient enrichment of selenium-enriched protein.
This device simplifies the protein purification process, reduces operational complexity and time-consuming, improves enrichment efficiency, avoids the problem of filter plate clogging, and can adapt to collection tubes of different sizes, ensuring the stability of collection tubes.
Smart Images
Figure CN222871575U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of enrichment, in particular to a selenium-enriched protein enrichment device. Background Art
[0002] In the field of biomedicine, selenium-rich protein enrichment devices are used to extract and purify selenium-rich proteins from complex biological samples. These proteins may have important biological activities, such as antioxidant, anti-inflammatory or other therapeutic potential, so their enrichment can provide important biological materials for new drug development and therapeutic research. Selenium-rich protein enrichment devices play a key role in the manufacture of nutritional health products and functional food raw materials. Selenium is an important trace element that is beneficial to human health, especially in enhancing the immune system, anti-oxidation and anti-inflammation. Through these devices, selenium-rich proteins can be extracted from natural foods or other sources for the preparation of high-quality nutritional supplements.
[0003] In modern biotechnology and pharmaceutical industries, the enrichment and purification of proteins with specific biological activities have important application value. Selenium-rich proteins, as a class of proteins with antioxidant and immune-enhancing functions, are increasingly in demand in the fields of food supplements and drug therapy. However, there are many challenges in effectively enriching and purifying selenium-rich proteins from complex biological solutions. Traditional protein purification methods such as centrifugation, filtration, and chromatography are often complicated to operate, time-consuming, and difficult to achieve efficient enrichment effects. Especially when dealing with large amounts or low-concentration samples, the filter plate will become clogged due to long-term use, and the filter plate needs to be disassembled and cleaned. Therefore, a selenium-rich protein enrichment device is proposed to solve the above problems. Utility Model Content
[0004] In order to make up for the above shortcomings, the utility model provides a selenium-rich protein enrichment device, aiming to improve the problem in the prior art that the filter plate cannot be disassembled and cleaned.
[0005] In order to achieve the above purpose, the utility model adopts the following technical solutions:
[0006] A selenium-rich protein enrichment device, comprising a bottom plate, the top right side of the bottom plate is fixedly connected to a height adjustment component, the external threaded connection of the height adjustment component is two screw rings, the left sides of the two screw rings are fixedly connected to a fixing plate 1, the left sides of the two fixing plates 1 are fixedly connected to an adsorption tube, the front and rear sides of the adsorption tube are provided with cavities, the tops of the two cavities are slidably connected to a pulling plate, the middle parts of the two pulling plates are fixedly connected to a limiting plate, the bottom of the pulling plate is rotatably connected to a connecting plate, the bottom of the connecting plate is rotatably connected to a clamping plate, a spring 1 is arranged inside the cavity, a filter plate is arranged inside the adsorption tube, a clamping groove is arranged in the middle parts of the front and rear sides of the filter plate, and an adsorption layer is arranged inside the adsorption tube;
[0007] As a further description of the above technical solution:
[0008] The height adjustment assembly includes a stud, the bottom of which is fixedly connected to the top right side of the bottom plate, and the middle parts of the two screw rings are both threadedly connected to the outside of the stud;
[0009] As a further description of the above technical solution:
[0010] A collecting pipe is arranged on the top of the bottom plate, and a second fixing plate is fixedly connected to both the front and rear sides of the top of the bottom plate, and sliding rods are slidably connected to both the left and right sides of the second fixing plate, and a second spring is sleeved on the outside of the two sliding rods, and one end of the sliding rod is fixedly connected to a clamping plate, and the other end of the sliding rod is fixedly connected to a limiting block;
[0011] As a further description of the above technical solution:
[0012] The outer portion of the clamping plate is slidably connected to the inner portion of the cavity, and the adjacent sides of the two clamping plates are respectively clamped with the inner portions of the two clamping grooves;
[0013] As a further description of the above technical solution:
[0014] One end of the spring 1 is fixedly connected to the inner wall of the cavity, and the other end of the spring 1 is fixedly connected to the outside of the clamping plate;
[0015] As a further description of the above technical solution:
[0016] The material of the adsorption layer is ion exchange resin, and the bottom of the limiting plate is in contact with the top of the adsorption tube;
[0017] As a further description of the above technical solution:
[0018] One end of the second spring is fixedly connected to the outside of the clamping plate, and the other end of the second spring is fixedly connected to the outside of the second fixing plate;
[0019] As a further description of the above technical solution:
[0020] The adjacent sides of the two clamping plates are in contact with the outside of the collecting tube, and the outside of the limiting block is in contact with the outside of the second fixing plate.
[0021] The utility model has the following beneficial effects:
[0022] 1. In the utility model, a solution containing selenium-rich protein is poured into the adsorption tube, and the filter plate filters the particles in the solution. Then, the filtered solution passes through the inside of the adsorption layer, and the adsorption layer adsorbs the selenium-rich protein in the solution, thereby completing the enrichment of the selenium-rich protein.
[0023] 2. In the utility model, the collecting tubes of different sizes can be clamped and fixed by the clamping plate, so as to prevent the collecting tube from tipping over due to excessive impact force of the solution when collecting the adsorbed solution. BRIEF DESCRIPTION OF THE DRAWINGS
[0024] Figure 1 This is a three-dimensional schematic diagram of a selenium-rich protein enrichment device proposed by the utility model;
[0025] Figure 2 This is a schematic diagram of the structure inside the cavity of a selenium-rich protein enrichment device proposed by the utility model;
[0026] Figure 3 This is a schematic diagram of the structure of an adsorption layer of a selenium-rich protein enrichment device proposed by the utility model;
[0027] Figure 4 for Figure 1 Enlarged view of point A in the middle.
[0028] Legend:
[0029] 1. Bottom plate; 2. Stud; 3. Screw ring; 4. Fixed plate 1; 5. Adsorption tube; 6. Cavity; 7. Pull plate; 8. Limit plate; 9. Connecting plate; 10. Clamping plate; 11. Spring 1; 12. Filter plate; 13. Clamping groove; 14. Adsorption layer; 15. Collecting tube; 16. Fixed plate 2; 17. Sliding rod; 18. Spring 2; 19. Limit block; 20. Clamping plate. DETAILED DESCRIPTION
[0030] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0031] Reference Figure 1 - Figure 3 The utility model provides an embodiment: a selenium-rich protein enrichment device, including a base plate 1, which is the basic supporting structure of the device and is usually made of a strong and durable material, such as steel or heavy plastic, to ensure the stability and durability of the entire device. The design of the base plate 1 needs to be able to bear the overall weight of the device and provide a fixed position for other components. The top right side of the base plate 1 is fixedly connected to a height adjustment component, and the external threaded connection of the height adjustment component is connected with two screw rings 3.
[0032] The height adjustment component includes a stud 2, the bottom of the stud 2 is fixedly connected to the top right side of the base plate 1, and the middle parts of the two screw rings 3 are threadedly connected to the outside of the stud 2. The design of the stud 2 allows the height of the entire device to be adjusted according to operational needs, thereby improving the applicability and flexibility of the device. The bottom of the stud 2 is fixed to the top of the base plate 1, and the screw ring 3 is used to fix and adjust the height to ensure the stability of the device during use. The left sides of the two screw rings 3 are fixedly connected to a fixing plate 4, and the left sides of the two fixing plates 4 are fixedly connected to an adsorption tube 5. The adsorption tube 5 has cavities 6 on both the front and rear sides. The tops of the two cavities 6 are slidably connected to a pulling plate 7, and the middle parts of the two pulling plates 7 are fixedly connected to a limiting plate 8. The bottom of the pulling plate 7 is rotatably connected to a connecting plate 9, and the bottom of the connecting plate 9 is rotatably connected to a clamping plate 10. A spring 11 is arranged inside the cavity 6, one end of the spring 11 is fixedly connected to the inner wall of the cavity 6, and the other end of the spring 11 is fixedly connected to the outside of the clamping plate 10.
[0033] The pulling plate 7 is connected to the cavity 6 of the adsorption tube 5 by sliding, and is fixedly connected to the limiting plate 8. The connecting plate 9 and the clamping plate 10 are used in combination, and the action of the spring 11 is used to realize rapid loading and unloading and replacement of the filter plate 12. The adsorption tube 5 is provided with a filter plate 12, and the middle parts of the front and rear sides of the filter plate 12 are provided with clamping grooves 13. The outside of the clamping plate 10 is slidably connected to the inside of the cavity 6, and the adjacent sides of the two clamping plates 10 are respectively clamped with the inside of the two clamping grooves 13. The adsorption tube 5 is provided with an adsorption layer 14. The material of the adsorption layer 14 is ion exchange resin. The adsorption tube 5 is the core part of the enrichment of selenium-rich protein. The filter plate 12 is responsible for the preliminary filtration of the solution containing selenium-rich protein and blocks larger particles, while the adsorption layer 14 is composed of ion exchange resin and is specially used for adsorbing selenium in the solution to realize the enrichment of selenium-rich protein. The bottom of the limiting plate 8 is in contact with the top of the adsorption tube 5.
[0034] Reference Figure 1 and Figure 4 A collecting tube 15 is arranged on the top of the bottom plate 1, and a fixing plate 2 16 is fixedly connected to the front and rear sides of the top of the bottom plate 1, and sliding rods 17 are slidably connected to the left and right sides of the fixing plate 2 16, and springs 2 18 are sleeved on the outside of the two sliding rods 17, and a clamping plate 20 is fixedly connected to one end of the sliding rod 17. The collecting tube 15 is a container for collecting the enriched solution, which is located on the top of the bottom plate 1 and is fixed by the structure of the clamping plate 20 and the sliding rod 17. This design can adapt to collecting tubes 15 of different sizes and ensure the stability of the collecting tube 15 under the impact force of the solution.
[0035] One end of spring 218 is fixedly connected to the outside of the clamping plate 20, the other end of spring 218 is fixedly connected to the outside of the fixed plate 216, and the other end of the sliding rod 17 is fixedly connected to the limiting block 19. The adjacent sides of the two clamping plates 20 are in contact with the outside of the collecting tube 15, and the outside of the limiting block 19 is in contact with the outside of the fixed plate 216. The clamping plate 20 is used to fix and stabilize the collecting tube 15 to prevent the collecting tube 15 from tipping over or shifting due to impact during operation. The sliding rod 17 is equipped with spring 218, which provides the necessary elasticity and adjustment ability, so that the clamping plate 20 can adapt to collecting tubes 15 of different sizes and easily replace or adjust the collecting tube 15 when necessary.
[0036] Working principle: First, a solution containing selenium-rich protein needs to be prepared. The operator pours the solution into the adsorption tube 5. The adsorption tube 5 is equipped with a filter plate 12. The filter plate 12 is located inside the adsorption tube 5 and is connected to the snap-fit groove 13 in the cavity 6 through the snap-fit plate 10. When the solution passes through the filter plate 12, larger particles are blocked, and only smaller particles and solution are allowed to pass.
[0037] The filtered solution contacts the adsorption layer 14 , which is composed of ion exchange resin. This resin is specifically used to adsorb selenium in the solution, thereby achieving the enrichment of selenium-rich proteins. As the solution flows, the selenium-rich proteins are captured by the adsorption layer 14 , and the unadsorbed solution continues to flow to the collection tube 15 .
[0038] The collecting tube 15 is located on the top of the base plate 1 and is fixed by the structure of the clamping plate 20 and the sliding rod 17. This structural design allows the clamping plate 20 to adapt to collecting tubes 15 of different sizes. At the same time, the spring 18 provides the necessary elasticity to ensure the stability of the collecting tube 15 when the solution flows. The clamping plate 20 is connected to the fixed plate 16 of the base plate 1 through the sliding rod 17, ensuring the stability and adjustability of the entire collecting system.
[0039] During the whole process, the operator can adjust the height of the adsorption tube 5 by adjusting the screw ring 3 on the height adjustment assembly. In addition, through the design of the pulling plate 7 and the connecting plate 9, the operator can easily replace or adjust the filter plate 12 and the adsorption layer 14 to adapt to different operating requirements or perform regular maintenance and cleaning.
[0040] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.
Claims
1. A selenium-rich protein enrichment device, comprising a bottom plate (1), characterized in that: The top right side of the bottom plate (1) is fixedly connected to a height adjustment component, and the external threaded connection of the height adjustment component is connected to two screw rings (3), and the left sides of the two screw rings (3) are fixedly connected to a fixing plate (4), and the left sides of the two fixing plates (4) are fixedly connected to an adsorption tube (5), and the adsorption tube (5) is provided with a cavity (6) on both the front and rear sides inside, and the tops of the two cavities (6) are slidably connected to a pulling plate (7), and the middle parts of the two pulling plates (7) are fixedly connected to a limiting plate (8), and the bottom of the pulling plate (7) is rotatably connected to a connecting plate (9), and the bottom of the connecting plate (9) is rotatably connected to a clamping plate (10), and a spring (11) is arranged inside the cavity (6), and a filter plate (12) is arranged inside the adsorption tube (5), and a clamping groove (13) is arranged in the middle of the front and rear sides of the filter plate (12), and an adsorption layer (14) is arranged inside the adsorption tube (5).
2. A selenium-rich protein enrichment device according to claim 1, characterized in that: The height adjustment assembly comprises a stud (2), the bottom of the stud (2) is fixedly connected to the top right side of the base plate (1), and the middle parts of the two screw rings (3) are both threadedly connected to the outside of the stud (2).
3. A selenium-rich protein enrichment device according to claim 1, characterized in that: A collecting pipe (15) is arranged on the top of the bottom plate (1), and a second fixing plate (16) is fixedly connected to the front and rear sides of the top of the bottom plate (1), and a sliding rod (17) is slidably connected to the left and right sides of the second fixing plate (16), and a second spring (18) is sleeved on the outside of the two sliding rods (17), one end of the sliding rod (17) is fixedly connected to a clamping plate (20), and the other end of the sliding rod (17) is fixedly connected to a limiting block (19).
4. A selenium-rich protein enrichment device according to claim 1, characterized in that: The outside of the clamping plate (10) is slidably connected to the inside of the cavity (6), and the adjacent sides of the two clamping plates (10) are respectively clamped with the inside of the two clamping grooves (13).
5. A selenium-rich protein enrichment device according to claim 1, characterized in that: One end of the spring one (11) is fixedly connected to the inner wall of the cavity (6), and the other end of the spring one (11) is fixedly connected to the outside of the clamping plate (10).
6. A selenium-rich protein enrichment device according to claim 1, characterized in that: The material of the adsorption layer (14) is ion exchange resin, and the bottom of the limiting plate (8) is in contact with the top of the adsorption tube (5).
7. A selenium-rich protein enrichment device according to claim 3, characterized in that: One end of the second spring (18) is fixedly connected to the outside of the clamping plate (20), and the other end of the second spring (18) is fixedly connected to the outside of the second fixing plate (16).
8. A selenium-rich protein enrichment device according to claim 3, characterized in that: The adjacent sides of the two clamping plates (20) are in contact with the outside of the collecting tube (15), and the outside of the limiting block (19) is in contact with the outside of the second fixing plate (16).