Sitagliptin phosphate metformin compound preparation mixing device

Abstract

The utility model relates to the technical field of mixing, in particular to a sitagliptin phosphate metformin compound preparation mixing device. The mixing device comprises a rack, a stirring assembly and a vibration assembly, the rack is of an L-shaped structure, a mixing tank is movably arranged above the horizontal section of the rack, a limiting supporting assembly matched with the rack is arranged at the bottom of the mixing tank, the stirring assembly used for mixing raw materials is arranged in the mixing tank, and the vibration assembly is arranged on one side of the vertical section of the rack. The mixing tank is movably arranged on the rack through the limiting and supporting assembly, and the stirring assembly, the output assembly and the oscillation assembly are matched, so that when the motor drives the transverse shaft and the stirring blades to stir and mix raw materials inside, the output mechanism can transmit stirring force to the oscillation assembly, and the stirring force is transmitted to the vibration assembly; the mixing tank is driven by the oscillation assembly to perform reciprocating translation on the rack under the cooperation of the limiting and supporting assembly, so that the uniformity and the mixing efficiency of the whole mixed material are improved.

Description

Technical Field

[0001] The utility model relates to the technical field of material mixing, in particular to a material mixing device for a sitagliptin phosphate metformin compound preparation. Background Art

[0002] Sitagliptin is an oral antidiabetic drug commonly used in the treatment of type 2 diabetes. Metformin is also an oral drug belonging to the sulfonylurea class of drugs commonly used to control blood sugar. As the name suggests, sitagliptin phosphate metformin combination preparation is a drug formula used to treat diabetes that contains sitagliptin phosphate and metformin. A mixing device is required to mix the raw materials during the production process.

[0003] A Chinese patent with authorization announcement number CN208612226U discloses a high-efficiency mixing equipment for pharmaceutical production, including a mixing tank, a No. 1 feeding box, a No. 2 feeding box, a No. 3 feeding box and a motor box. A No. 1 feeding box is arranged on one side above the mixing tank, a No. 2 feeding box is arranged on one side of the No. 1 feeding box, a No. 3 feeding box is arranged on one side of the No. 2 feeding box, a motor box is fixedly connected to one side of the mixing tank, a stirring rod is rotatably connected to the inside of the mixing tank through a fixed shaft, a stirring blade is fixedly connected to the surface of the stirring rod, a driving motor is connected to one end of the stirring rod and the driving motor is located inside the motor box.

[0004] However, the above-mentioned mixing equipment only mixes and stirs the raw materials by rotating the fixed shaft and the stirring rod driven by the motor, and its mixing effect is general and the mixing efficiency is poor. Utility Model Content

[0005] In view of the problems existing in the background technology, a mixing device for sitagliptin phosphate and metformin compound preparation is proposed. A mixing tank is movably arranged on a frame through a limit support assembly, and a stirring assembly, an output assembly and an oscillating assembly are used to cooperate. When a motor drives a horizontal axis and a stirring blade to stir and mix the raw materials inside, the mixing tank is driven to reciprocate on the frame through the oscillating assembly, thereby improving the uniformity and mixing efficiency of the overall mixed ingredients.

[0006] The utility model provides a mixing device for a sitagliptin phosphate metformin compound preparation, comprising

[0007] The frame is arranged in an L-shaped structure, a mixing tank is movably arranged above the horizontal section, and a limiting support assembly cooperating with the frame is arranged at the bottom of the mixing tank;

[0008] A stirring assembly is arranged inside the mixing tank and is used to mix the raw materials; and

[0009] The oscillating assembly is arranged on one side of the vertical section of the frame and has an output mechanism matched with the stirring assembly for driving the mixing tank to reciprocate and oscillate and translate under the limit of the limit support assembly.

[0010] Preferably, a feed pipe is provided at the top of the mixing tank, a hopper is provided on the feed pipe, a discharge pipe is provided at the bottom of the mixing tank, and a manual valve is provided on the discharge pipe.

[0011] Preferably, the limit support assembly includes a limit frame and a movable plate, and two groups of limit frames and movable plates are provided. The two groups of limit frames are respectively installed on both sides of the top of the horizontal section of the frame, and the two groups of movable plates are slidably arranged between the two groups of limit frames, and the mixing tank is horizontally installed on the two groups of movable plates.

[0012] Preferably, rollers are rotatably provided at both ends of the bottom of the two sets of movable plates, and the two sets of rollers are provided in contact with the horizontal section of the frame, and are used to assist in supporting the mixing tank through the movable plates.

[0013] Preferably, the stirring assembly includes a motor, a transverse shaft and stirring blades. The motor is installed at one end of the mixing tank away from the vertical section of the frame, and its output end is connected to the transverse shaft located in the mixing tank. Multiple groups of stirring blades are circumferentially equidistantly arranged on the outside of the transverse shaft.

[0014] Preferably, the oscillation assembly includes a vertical shaft, a turntable and a push rod. A fixed seat is provided on the side of the vertical section of the frame. The vertical shaft rotates through the fixed seat. The bottom end of the vertical shaft is connected to the turntable. The eccentric part of the lower end surface of the turntable is rotatably connected to one end of the push rod, and the other end of the push rod is rotatably connected to the mixing tank.

[0015] Preferably, the output mechanism includes a sleeve, a connecting shaft, a rotation limiter and a deceleration linkage member, one end of the sleeve is rotatably connected to the side wall of the vertical section of the frame through a bearing, and the other end is interspersed with a connecting shaft, and the end of the connecting shaft away from the sleeve is connected to the horizontal axis; a rotation limiter is arranged between the sleeve and the connecting shaft, and a deceleration linkage member is arranged between the sleeve and the vertical axis.

[0016] Preferably, the rotation limiting member comprises a convex strip, and both sides of the inner wall of the sleeve are integrally formed with the convex strip, and both sides of the outer wall of the connecting shaft are provided with a limiting groove embedded with the convex strip.

[0017] Preferably, the reduction linkage comprises a bevel gear a and a bevel gear b, wherein the bevel gear a is mounted on the sleeve, and the bevel gear b is mounted on the top end of the vertical shaft, and the bevel gear b is meshedly connected with the bevel gear a.

[0018] Preferably, the diameter of the bevel gear b is much larger than the diameter of the bevel gear a.

[0019] Through the above technical scheme, that is, the mixing device disclosed in the utility model, a mixing tank is movably arranged on the frame through a limit support assembly, and by utilizing the cooperation of the stirring assembly, the output assembly and the oscillation assembly, when the motor drives the horizontal axis and the stirring blades to stir and mix the internal raw materials, the output mechanism will transmit the stirring force to the oscillation assembly, and the mixing tank is driven by the oscillation assembly to reciprocate on the frame with the cooperation of the limit support assembly. During the movement, the raw materials of different parts can be mixed together more effectively, thereby improving the uniformity and mixing efficiency of the overall mixed ingredients.

[0020] Additional aspects and advantages of the present invention will be given in part in the following description, and in part will become apparent from the following description, or will be learned through the practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 This is a schematic diagram of the structure of a mixing device for a sitagliptin phosphate metformin compound preparation of the utility model;

[0022] Figure 2 for Figure 1 Schematic diagram of the side structure;

[0023] Figure 3 for Figure 2 A schematic diagram of a side cross-section structure;

[0024] Figure 4 for Figure 1 Schematic diagram of the local enlarged structure.

[0025] Figure numerals: 1, frame; 2, mixing tank; 3, feed pipe; 4, hopper; 5, discharge pipe; 6, limit frame; 7, moving plate; 8, roller; 9, motor; 10, horizontal axis; 11, stirring blade; 12, vertical axis; 13, turntable; 14, push rod; 15, fixed seat; 16, sleeve; 17, connecting shaft; 18, convex strip; 19, limit groove; 20, bevel gear a; 21, bevel gear b. DETAILED DESCRIPTION

[0026] The specific implementation of the present disclosure is described in detail below in conjunction with the accompanying drawings. It should be understood that the specific implementation described herein is only used to illustrate and explain the present disclosure, and is not used to limit the present disclosure.

[0027] Embodiment 1

[0028] like Figure 1-Figure 4As shown, a mixing device for a sitagliptin phosphate and metformin compound preparation proposed by the utility model comprises a frame 1, a stirring assembly and an oscillating assembly. The frame 1 is arranged as an L-shaped structure, a mixing tank 2 is movably arranged above the horizontal section thereof, a limiting support assembly cooperating with the frame 1 is arranged at the bottom of the mixing tank 2, a stirring assembly for mixing raw materials is arranged inside the mixing tank 2, and the oscillating assembly is arranged on one side of the vertical section of the frame 1, and an output mechanism cooperating with the stirring assembly is provided thereon, which is used to push the mixing tank 2 to reciprocate and oscillate and translate under the limit of the limiting support assembly.

[0029] like Figure 1 and Figure 3 As shown, a feed pipe 3 is provided on the top of the mixing tank 2, a hopper 4 is provided on the feed pipe 3, a discharge pipe 5 is provided at the bottom of the mixing tank 2, and a manual valve is provided on the discharge pipe 5. The raw materials to be mixed are injected into the mixing tank 2 through the cooperation of the hopper 4 and the feed pipe 3, and the discharge pipe 5 can be opened through the manual valve to discharge the mixed raw materials.

[0030] like Figure 2 As shown, the limiting support assembly includes a limiting frame 6 and a movable plate 7, and two groups of the limiting frame 6 and the movable plate 7 are provided. The two groups of limiting frames 6 are respectively installed on both sides of the top of the horizontal section of the frame 1, and the two groups of movable plates 7 are slidably arranged between the two groups of limiting frames 6, and the mixing tank 2 is horizontally installed on the two groups of movable plates 7.

[0031] like Figure 1 As shown, rollers 8 are rotatably provided at both ends of the bottom of the two groups of movable plates 7 , and the two groups of rollers 8 are both provided in contact with the horizontal section of the frame 1 , and are used for auxiliary support of the mixing tank 2 through the movable plates 7 .

[0032] The mixing tank 2 is movably mounted on two limit frames 6 by means of a movable plate 7 and is auxiliary-supported by rollers 8, thereby reducing the force exerted by the oscillating component on the mixing tank 2 when it is pushed.

[0033] like Figure 3 As shown, the stirring assembly includes a motor 9, a horizontal axis 10 and stirring blades 11. The motor 9 is installed at one end of the mixing tank 2 away from the vertical section of the frame 1, and its output end is connected to the horizontal axis 10 located in the mixing tank 2. A plurality of groups of stirring blades 11 are circumferentially and equidistantly arranged on the outside of the horizontal axis 10.

[0034] Embodiment 2

[0035] like Figure 1-Figure 3 As shown, the utility model proposes a mixing device for a sitagliptin phosphate and metformin compound preparation. Based on the above embodiments, this embodiment also records in detail the specific structures of the oscillating component and the output mechanism, as well as the coordination mode of the two with the stirring component.

[0036] like Figure 3 and Figure 4 As shown, the oscillation assembly includes a vertical shaft 12, a turntable 13 and a push rod 14. A fixed seat 15 is provided on the side of the vertical section of the frame 1. The vertical shaft 12 is rotatably penetrated on the fixed seat 15. The bottom end of the vertical shaft 12 is connected to the turntable 13. The eccentric part of the lower end surface of the turntable 13 is rotatably connected to one end of the push rod 14, and the other end of the push rod 14 is rotatably connected to the mixing tank 2.

[0037] The vertical shaft 12 is driven to rotate by the output mechanism, and the turntable 13 at the bottom of the vertical shaft 12 rotates synchronously, so that one end of the push rod 14 moves in a circular trajectory, and the other end of the push rod 14 pulls the mixing tank 2 to reciprocate under the limit of the limit frame 6.

[0038] like Figure 3 As shown, the output mechanism includes a sleeve 16, a connecting shaft 17, a rotation limiter and a reduction linkage. One end of the sleeve 16 is rotationally connected to the side wall of the vertical section of the frame 1 through a bearing, and the other end is interspersed with a connecting shaft 17. The end of the connecting shaft 17 away from the sleeve 16 is connected to the horizontal axis 10; a rotation limiter is provided between the sleeve 16 and the connecting shaft 17, and a reduction linkage is provided between the sleeve 16 and the vertical axis 12.

[0039] like Figure 4 As shown, the rotation limiting member includes a convex strip 18 , and the convex strips 18 are integrally formed on both sides of the inner wall of the sleeve 16 , and limiting grooves 19 embedded with the convex strips 18 are formed on both sides of the outer wall of the connecting shaft 17 .

[0040] Through the cooperation between the convex strip 18 and the limiting groove 19 , when the connecting shaft 17 rotates under the action of the transverse shaft 10 , it will drive the sleeve 16 to rotate synchronously.

[0041] like Figure 3 As shown, the reduction linkage comprises a bevel gear a20 and a bevel gear b21. The bevel gear a20 is mounted on the sleeve 16, and the bevel gear b21 is mounted on the top of the vertical shaft 12. The bevel gear b21 is meshed and connected with the bevel gear a20.

[0042] like Figure 3 As shown, the diameter of bevel gear b21 is much larger than the diameter of bevel gear a20.

[0043] The bevel gear a20 is driven to rotate by the rotation of the sleeve 16, and the bevel gear a20 is meshed with the bevel gear b21, and the meshing force drives the vertical shaft 12 to rotate at a reduced speed.

[0044] In summary, during the use of the utility model, the raw materials of the compound preparation to be mixed are injected into the mixing tank 2 through the hopper 4 and the feed pipe 3. After the injection is completed, the motor 9 is started, and the motor 9 drives the stirring blade 11 to rotate through the horizontal shaft 10. The raw materials are stirred and mixed during the rotation. When the horizontal shaft 10 rotates under the action of the motor 9, it will drive the connecting shaft 17 to rotate synchronously. The connecting shaft 17 drives the sleeve 16 to rotate under the adaptation of the limit groove 19 and the convex strip 18, and the rotation of the sleeve 16 drives the bevel gear a20 to rotate. The bevel gear a20 is meshed with the bevel gear b21, and the meshing force drives the vertical shaft 12 to reduce the rotation. When the vertical shaft 12 rotates, the turntable 13 at its bottom end rotates synchronously, so that one end of the push rod 14 moves in a circular trajectory, and the other end of the push rod 14 pulls the mixing tank 2 to reciprocate under the limit of the limit frame 6, thereby improving the mixing effect and mixing efficiency as a whole.

[0045] The implementation modes of the present invention are described in detail above in conjunction with the accompanying drawings, but the present invention is not limited thereto, and various changes can be made within the knowledge scope of technicians in the relevant technical field without departing from the purpose of the present invention.

Claims

1. A mixing device for a sitagliptin phosphate and metformin compound preparation, characterized in that: include The frame (1) is arranged in an L-shaped structure, a mixing tank (2) is movably arranged above the horizontal section, and a limiting support assembly cooperating with the frame (1) is arranged at the bottom of the mixing tank (2); A stirring assembly is arranged inside the mixing tank (2) and is used to mix the raw materials; and The oscillating assembly is arranged on one side of the vertical section of the frame (1) and has an output mechanism that cooperates with the stirring assembly and is used to push the mixing tank (2) to reciprocate and oscillate in translation under the limit of the limit support assembly.

2. A mixing device for sitagliptin phosphate and metformin compound preparation according to claim 1, characterized in that: A feed pipe (3) is arranged on the top of the mixing tank (2), a hopper (4) is arranged on the feed pipe (3), a discharge pipe (5) is arranged on the bottom of the mixing tank (2), and a manual valve is arranged on the discharge pipe (5).

3. A mixing device for sitagliptin phosphate and metformin compound preparation according to claim 1, characterized in that: The limiting support assembly comprises a limiting frame (6) and a movable plate (7), wherein the limiting frame (6) and the movable plate (7) are both provided in two groups, the two groups of limiting frames (6) are respectively installed on both sides of the top of the horizontal section of the frame (1), the two groups of movable plates (7) are slidably arranged between the two groups of limiting frames (6), and the mixing tank (2) is horizontally installed on the two groups of movable plates (7).

4. A mixing device for sitagliptin phosphate and metformin compound preparation according to claim 3, characterized in that: Rollers (8) are rotatably arranged at both ends of the bottom of the two groups of movable plates (7), and the two groups of rollers (8) are arranged in contact with the horizontal section of the frame (1) and are used to assist in supporting the mixing tank (2) through the movable plates (7).

5. A mixing device for sitagliptin phosphate and metformin compound preparation according to claim 1, characterized in that: The stirring assembly comprises a motor (9), a transverse shaft (10) and stirring blades (11). The motor (9) is mounted at one end of the mixing tank (2) away from the vertical section of the frame (1), and the output end of the motor (9) is connected to the transverse shaft (10) located in the mixing tank (2). A plurality of groups of stirring blades (11) are equidistantly arranged on the outer side of the transverse shaft (10) in the circumferential direction.

6. A mixing device for sitagliptin phosphate and metformin compound preparation according to claim 5, characterized in that: The oscillating assembly comprises a vertical shaft (12), a rotating disk (13) and a push rod (14); a fixed seat (15) is arranged on the side of the vertical section of the frame (1); the vertical shaft (12) is rotatably penetrated on the fixed seat (15); the bottom end of the vertical shaft (12) is connected to the rotating disk (13); the eccentric part of the lower end surface of the rotating disk (13) is rotatably connected to one end of the push rod (14); and the other end of the push rod (14) is rotatably connected to the mixing tank (2).

7. A mixing device for sitagliptin phosphate and metformin compound preparation according to claim 6, characterized in that: The output mechanism comprises a sleeve (16), a connecting shaft (17), a rotation limiter and a speed reduction linkage member; one end of the sleeve (16) is rotationally connected to the side wall of the vertical section of the frame (1) via a bearing, and the other end is interspersed with a connecting shaft (17); the end of the connecting shaft (17) away from the sleeve (16) is connected to the transverse shaft (10); A rotation limiting member is provided between the sleeve (16) and the connecting shaft (17), and a speed reducing linkage member is provided between the sleeve (16) and the vertical shaft (12).

8. A mixing device for sitagliptin phosphate and metformin compound preparation according to claim 7, characterized in that: The rotation limiting member comprises a convex strip (18), the convex strips (18) are integrally formed on both sides of the inner wall of the sleeve (16), and limiting grooves (19) embedded with the convex strips (18) are provided on both sides of the outer wall of the connecting shaft (17).

9. A mixing device for sitagliptin phosphate and metformin compound preparation according to claim 7, characterized in that: The speed reduction linkage comprises a bevel gear a (20) and a bevel gear b (21), wherein the bevel gear a (20) is mounted on the sleeve (16), and the bevel gear b (21) is mounted on the top end of the vertical shaft (12), and the bevel gear b (21) is meshedly connected with the bevel gear a (20).

10. A mixing device for sitagliptin phosphate and metformin compound preparation according to claim 9, characterized in that: The diameter of bevel gear b (21) is much larger than the diameter of bevel gear a (20).

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