Small molecule detection device

By designing a small molecule detection device with a transmission system, the problem of inconsistent detection results caused by manual addition of drug liquid is solved, and the quantitative output of drug liquid and the accuracy of detection results is achieved.

CN222882703UActive Publication Date: 2025-05-16SHIHEZI UNIVERSITY
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202421371525.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-17
Publication Date
2025-05-16
Estimated Expiration
2034-06-17

AI Technical Summary

Technical Problem

The existing small molecule detection device manually adds the drug solution, resulting in inconsistent amounts of each addition, affecting the accuracy of the detection results.

Method used

A small molecule detection device is designed, including a mixing barrel, a transmission rod, a rotating disk, an extension column, a pushing plate and a discharge barrel. The transmission rod is driven by a motor to drive the rotating disk to rotate, and the plate is pushed to push the discharge barrel to achieve quantitative output of the medicine liquid.

Benefits of technology

By quantitatively outputting the drug solution, the accuracy of the test results is ensured and the reliability of the test is improved.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN222882703U_ABST
    Figure CN222882703U_ABST
Patent Text Reader

Abstract

The utility model relates to the technical field of detection devices, and discloses a small molecule detection device which comprises a bottom plate, the right end of the top of the bottom plate is fixedly connected with a mixing barrel, the front end of the top of the mixing barrel is provided with a feeding pipe, the right end of the top of the mixing barrel is fixedly connected with a first motor, and the driving end of the first motor is fixedly connected with a transmission rod. A rotating disc is fixedly connected to the left end of the transmission rod, an extension column is fixedly connected to the left end of the rotating disc, a rotating ring is rotatably connected to the outer portion of the extension column, a connecting rod is fixedly connected to the bottom of the rotating ring, a pushing plate is rotatably connected to the bottom of the connecting rod, and a discharging barrel is slidably connected to the outer portion of the pushing plate. According to the discharging device, when the rotating disc rotates, the extending column can be driven to push the rotating ring, so that the connecting rod pushes the pushing plate to move, materials in the discharging barrel can be controlled to be output from the discharging pipe, quantitative output can be performed every time, and the subsequent detection effect is ensured.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The utility model relates to the technical field of detection devices, in particular to a small molecule detection device. Background Art

[0002] Small molecules refer to molecules with a smaller molecular weight. In chemistry, small molecules usually refer to organic or inorganic molecules with relatively small molecular weights, such as oxygen (O2), sugars, ammonia (NH3), methane (CH4), etc., while in biology, small molecules usually refer to organic substances with a smaller molecular weight that work in organisms, such as amino acids, nucleotides, sugars, fatty acids, etc. These small molecules are the basic substances for various biochemical reactions in organisms, and they can be synthesized into macromolecules such as proteins, nucleic acids, polysaccharides and lipids through enzyme catalysis. Among them, small molecules need to be detected, and small molecule detection has important applications in many fields, including environmental science, food safety, drug discovery and medical research.

[0003] Some existing liquid medicine detection devices perform detection by manually adding liquid medicine during detection. However, manual addition will result in inconsistent amounts added each time, leading to different detection results, thereby reducing the accuracy of the test. Therefore, a small molecule detection device is proposed to solve the above problem. Utility Model Content

[0004] In order to make up for the above shortcomings, the utility model provides a small molecule detection device, which aims to improve the problem in the prior art that manual addition of materials for detection may lead to different detection results.

[0005] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0006] A small molecule detection device, comprising a bottom plate, a mixing barrel is fixedly connected to the top right end of the bottom plate, a feeding pipe is arranged at the top front end of the mixing barrel, a motor is fixedly connected to the top right end of the mixing barrel, a driving end of the motor is fixedly connected to a transmission rod, a rotating disk is fixedly connected to the left end of the transmission rod, an extension column is fixedly connected to the left end of the rotating disk, a rotating ring is rotatably connected to the outside of the extension column, a connecting rod is fixedly connected to the bottom of the rotating ring, a push plate is rotatably connected to the bottom of the connecting rod, a discharging barrel is slidably connected to the outside of the push plate, a transmission assembly is fixedly connected to the outside of the transmission rod, a stirring assembly is fixedly connected to the bottom of the transmission assembly, a discharging pipe is fixedly connected to the left end of the discharging barrel, a fixed block is fixedly connected to the top of the bottom plate, a support frame is fixedly connected to the top of the support frame, a cylinder is fixedly connected to the driving end of the cylinder, a mounting disk is fixedly connected to the driving end of the cylinder, a detection head is arranged at the bottom of the mounting disk, and a scale is fixedly connected to the rear end of the discharging barrel;

[0007] As a further description of the above technical solution:

[0008] The transmission assembly includes a driving bevel gear, which is fixedly connected to the outside of the transmission rod, and a driven bevel gear is rotatably connected to the top of the mixing barrel, and the driving bevel gear and the driven bevel gear are meshingly connected;

[0009] As a further description of the above technical solution:

[0010] The stirring assembly comprises a rotating rod, the top of which is fixedly connected to the bottom of the driven bevel gear, a plurality of stirring plates are fixedly connected to both sides of the outside of the rotating rod, and the bottom of the rotating rod is rotatably connected to the bottom inner wall of the mixing barrel;

[0011] As a further description of the above technical solution:

[0012] The front end of the mixing barrel is fixedly connected with a connecting pipe, the other end of the connecting pipe is fixedly connected to the front end of the discharging barrel, and a one-way valve is arranged on the top of the connecting pipe;

[0013] As a further description of the above technical solution:

[0014] Extension blocks are fixedly connected to both sides of the exterior of the detection head, sliding columns are fixedly and slidably connected to both sides of the mounting plate, a spring is sleeved on the exterior of the sliding column, a limiting block is fixedly connected to one side of the sliding column, a clamping block is fixedly connected to one end of the limiting block away from the sliding column, and the exterior of the clamping block is engaged with the through hole of the extension block;

[0015] As a further description of the above technical solution:

[0016] The interior of the fixed block is fixedly connected with a second motor, the driving end of the second motor is fixedly connected with a carrier plate, the top of the carrier plate is slidably connected with a plurality of containers, and the outside of the carrier plate is rotatably connected to the inner wall of the fixed block;

[0017] As a further description of the above technical solution:

[0018] The bottom of the discharge barrel is fixedly connected to the top of the bottom plate, a slot is provided inside the mounting plate, and the outside of the extension block is slidably connected to the inner wall of the slot;

[0019] As a further description of the above technical solution:

[0020] One end of the spring is fixedly connected to one side of the limiting block, and the other end of the spring is fixedly connected to an inner wall of one side of the mounting plate.

[0021] The utility model has the following beneficial effects:

[0022] 1. In the utility model, by starting motor 1, the starting of motor 1 can drive the transmission rod to rotate the rotating disk, so that when the rotating disk rotates, it can drive the extension column to push the rotating ring so that the connecting rod pushes the pushing plate to move, thereby controlling the material inside the discharge barrel to be output from the discharge pipe, and can output quantitatively each time, thereby ensuring the subsequent detection effect and improving the accuracy of the detection.

[0023] 2. In the utility model, by pulling the sliding column, the sliding column drives the limiting block to squeeze the spring. At this time, the detection head can be rotated. The rotation of the detection head drives the extension block to slide on the inner wall of the slot. When it is rotated to a suitable position, the detection head can be pulled downward, thereby disassembling the detection head for easy cleaning and maintenance. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 This is a three-dimensional schematic diagram of a small molecule detection device proposed by the utility model;

[0025] Figure 2 This is a schematic diagram of the structure of a push plate of a small molecule detection device proposed by the utility model;

[0026] Figure 3 This is a schematic diagram of the structure of a rotating disk of a small molecule detection device proposed by the utility model;

[0027] Figure 4 This is a schematic diagram of the structure of a card block of a small molecule detection device proposed by the utility model;

[0028] Figure 5 This is a schematic structural diagram of a spring of a small molecule detection device proposed by the utility model.

[0029] Legend:

[0030] 1. Bottom plate; 2. Mixing barrel; 3. Feed pipe; 4. Motor 1; 5. Rotating plate; 6. Extension column; 7. Rotating ring; 8. Connecting rod; 9. Pushing plate; 10. Discharging barrel; 11. Transmission rod; 12. Active bevel gear; 13. Driven bevel gear; 14. Rotating rod; 15. Stirring plate; 16. Connecting pipe; 17. One-way valve; 18. Discharging pipe; 19. Fixed block; 20. Support frame; 21. Cylinder; 22. Mounting plate; 23. Detection head; 24. Extension block; 25. Sliding column; 26. Spring; 27. Limiting block; 28. Block; 29. ​​Slot; 30. Motor 2; 31. Carrying plate; 32. Container. DETAILED DESCRIPTION

[0031] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0032] Reference Figure 1-Figure 2 The utility model provides an embodiment: a small molecule detection device, including a bottom plate 1, the bottom plate 1 is the foundation and support structure of the entire small molecule detection device, a mixing barrel 2 is fixedly connected to the top right end of the bottom plate 1, the mixing barrel 2 is a container for mixing the sample to be tested and the detection reagents such as the fluorescent probe, a feeding pipe 3 is arranged at the top front end of the mixing barrel 2, the feeding pipe 3 is a channel for putting the sample to be tested into the mixing barrel 2, a motor 4 is fixedly connected to the top right end of the mixing barrel 2, so that the motor 4 can be stable during operation, and a driving end of the motor 4 is fixedly connected to a transmission rod 11, which can drive the transmission rod 11 to rotate when the motor 4 is started.

[0033] The left end of the transmission rod 11 is fixedly connected with a rotating disk 5, and the transmission rod 11 can drive the rotating disk 5 to rotate during the rotation process. The left end of the rotating disk 5 is fixedly connected with an extension column 6. When the rotating disk 5 rotates, the extension column 6 can be rotated. The outer rotation of the extension column 6 is connected with a rotating ring 7, and the rotation of the extension column 6 can drive the rotating ring 7 to rotate. The bottom of the rotating ring 7 is fixedly connected with a connecting rod 8, and the rotating ring 7 can push the connecting rod 8 to move. The bottom of the connecting rod 8 is rotatably connected with a pushing plate 9, and the pushing plate 9 is driven to move by the connecting rod 8. The outer sliding connection of the pushing plate 9 is connected with a discharging barrel 10, and the movement of the pushing plate 9 can push the liquid medicine inside the discharging barrel 10 to realize quantitative discharging. The bottom of the discharging barrel 10 is fixedly connected to the top of the bottom plate 1, so that the discharging barrel 10 is supported, and the rear end of the discharging barrel 10 is fixedly connected with a scale, and the scale is made of transparent material, and the amount of liquid medicine to be discharged from the discharging barrel 10 can be seen through the scale.

[0034] refer to Figure 2-Figure 3The outside of the transmission rod 11 is fixedly connected with a transmission assembly, which can be driven to rotate by the transmission rod 11. The bottom of the transmission assembly is fixedly connected with a stirring assembly, which can be driven to stir by the rotation of the transmission assembly. The transmission assembly includes an active bevel gear 12, which is fixedly connected to the outside of the transmission rod 11, so that the driving bevel gear 12 can be driven to rotate during the rotation of the transmission rod 11. The top of the mixing barrel 2 is rotatably connected with a driven bevel gear 13, and the active bevel gear 12 and the driven bevel gear 13 are meshed. When the active bevel gear 12 is in a meshing connection, the driven bevel gear 13 is in a meshing connection. 12 can drive the driven bevel gear 13 to rotate, and the stirring assembly includes a rotating rod 14. The top of the rotating rod 14 is fixedly connected to the bottom of the driven bevel gear 13. The rotation of the driven bevel gear 13 will drive the rotating rod 14 to rotate. Both sides of the outside of the rotating rod 14 are fixedly connected with multiple stirring plates 15. When the rotating rod 14 rotates, it can drive the stirring plates 15 to rotate so as to stir and mix the liquid medicine inside the mixing barrel 2. The bottom of the rotating rod 14 is rotatably connected to the bottom inner wall of the mixing barrel 2, so that the rotating rod 14 can be more stable when rotating.

[0035] refer to Figure 1 and Figure 3 The left end of the discharge barrel 10 is fixedly connected with a discharge pipe 18, and the front end of the mixing barrel 2 is fixedly connected with a connecting pipe 16. The other end of the connecting pipe 16 is fixedly connected to the front end of the discharge barrel 10. The connecting pipe 16 connects the mixing barrel 2 with the discharge barrel 10 to ensure that the mixed sample can smoothly enter the discharge barrel 10. A one-way valve 17 is arranged on the top of the connecting pipe 16. The function of this one-way valve 17 is to prevent backflow and ensure that the sample can only flow in one direction. A fixed block 19 is fixedly connected to the left end of the top of the bottom plate 1, and a support frame 20 is fixedly connected to the top of the fixed block 19. A cylinder 21 is fixedly connected to the top of the support frame 20, so that the cylinder 21 can be supported stably. The driving end of the cylinder 21 is fixedly connected with a mounting disk 22, which can drive the mounting disk 22 to move when the cylinder 21 is started. A detection head 23 is arranged at the bottom of the mounting disk 22, and the movement of the mounting disk 22 can drive the detection head 23 to move.

[0036] refer to Figure 4-Figure 5, both sides of the outside of the detection head 23 are fixedly connected with extension blocks 24, and the detection head 23 can be restricted by the extension blocks 24, and both sides of the mounting plate 22 are fixedly and slidably connected with sliding columns 25, and the outer sleeve of the sliding column 25 is provided with a spring 26, and the spring 26 is restricted by the sliding column 25. One side of the sliding column 25 is fixedly connected with a limiting block 27, and when the sliding column 25 is pulled, the limiting block 27 can be pulled to move, one end of the spring 26 is fixedly connected to one side of the limiting block 27, and the other end of the spring 26 is fixedly connected to the inner wall of one side of the mounting plate 22, and when the limiting block 27 moves, it can squeeze the spring 26 so that the spring 26 is deformed to generate elastic potential energy, and the end of the limiting block 27 away from the sliding column 25 is fixedly connected with a card block 28, so that the limiting block 27 can drive the card block 28 to move when it moves. The outer part of the card block 28 is engaged with the through hole of the extension block 24, so that the extension block 24 is restricted and the detection head 23 is restricted. The interior of the mounting plate 22 is provided with a slot hole 29, and the outer part of the extension block 24 is slidably connected to the inner wall of the slot hole 29, so that the extension block 24 is further restricted. The interior of the fixed block 19 is fixedly connected with a motor 2 30, and the driving end of the motor 2 30 is fixedly connected with a carrier plate 31, which can drive the carrier plate 31 to rotate when the motor 30 is started. The top of the carrier plate 31 is slidably connected with a plurality of containers 32, and the top of the carrier plate 31 is provided with a plurality of grooves, and the containers 32 are placed in the grooves, so that the containers 32 can be easily taken out, and the outer part of the carrier plate 31 is rotatably connected to the inner wall of the fixed block 19, so that the carrier plate 31 can rotate stably and drive the containers 32.

[0037] Working principle: When the device is needed to detect small molecules, the liquid is added into the mixing barrel 2 through the feed pipe 3. At this time, the motor 4 is started and the one-way valve 17 is opened. The rotation of the motor 4 can drive the transmission rod 11 to rotate, and the transmission rod 11 will also drive the active bevel gear 12 to rotate when it rotates. At this time, the active bevel gear 12 meshes with the driven bevel gear 13 so that the driven bevel gear 13 rotates. When the driven bevel gear 13 rotates, the rotating rod 14 drives the stirring plate 15 to rotate, thereby mixing the liquid medicine inside the mixing barrel 2 to make the liquid medicine uniform. When the transmission rod 11 rotates, it will also drive the rotating disk 5 to rotate. At this time, the rotation of the rotating disk 5 brings As the extension column 6 rotates, the rotation of the extension column 6 can push the rotating ring 7 to move the connecting rod 8. At this time, the movement of the connecting rod 8 can push the pushing plate 9 to slide on the inner wall of the discharge barrel 10, so that the medicine liquid inside the discharge barrel 10 is discharged from the discharge pipe 18 and enters the vessel 32. During the process, the motor 2 30 is started to drive the supporting plate 31 to rotate, so that the supporting plate 31 drives the vessel 32 to move, so that multiple vessels 32 can be added, and the cylinder 21 is started to drive the mounting plate 22 to make the detection head 23 detect the medicine liquid in the vessel 32, so that under the rotation of the vessel 32 and the detection of the detection head 23 driven by the cylinder 21, multiple samples can be detected to ensure the accuracy of the detection results.

[0038] Finally, when the detection head 23 needs to be cleaned or replaced, the sliding column 25 is pulled, and the movement of the sliding column 25 can drive the limiting block 27 to move. At this time, the movement of the limiting block 27 can squeeze the spring 26, so that the limiting block 27 is deformed to generate elastic potential energy. At this time, the movement of the limiting block 27 will also drive the clamping block 28 to move. At this time, the clamping block 28 will exit the through hole of the extension block 24, so that the detection head 23 can be rotated. At this time, the rotation of the detection head 23 can drive the extension block 24 to rotate so that the extension block 24 slides on the inner wall of the slot 29. When the closing position is reached, When it is in the appropriate position, the detection head 23 can be pulled out from the bottom of the mounting disk 22 to complete the disassembly. When it needs to be installed, pull the sliding column 25, and then insert the detection head 23 into the bottom of the mounting disk 22, so that the extension block 24 slides from the recess of the mounting disk 22, and then rotate the detection head 23 to make the extension block 24 slide on the inner wall of the slot 29. When it reaches the appropriate position, release the sliding column 25, which will cause the spring 26 to release its elastic potential energy, thereby pushing the limiting block 27 to drive the card block 28 to reset. When the card block 28 is reset, it can engage with the through hole of the extension block 24, thereby completing the installation.

[0039] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A small molecule detection device, comprising a base plate (1), characterized in that: The top right end of the bottom plate (1) is fixedly connected to a mixing barrel (2), the top front end of the mixing barrel (2) is provided with a feeding pipe (3), the top right end of the mixing barrel (2) is fixedly connected to a motor 1 (4), the driving end of the motor 1 (4) is fixedly connected to a transmission rod (11), the left end of the transmission rod (11) is fixedly connected to a rotating disk (5), the left end of the rotating disk (5) is fixedly connected to an extension column (6), the outside of the extension column (6) is rotatably connected to a rotating ring (7), the bottom of the rotating ring (7) is fixedly connected to a connecting rod (8), the bottom of the connecting rod (8) is rotatably connected to a push plate (9), the outside of the push plate (9) is fixedly connected to a rotating ring (7), and the bottom of the pushing plate (9) is fixedly connected to a rotating ring (7). The bottom of the bottom plate (1) is slidably connected to a discharge barrel (10), the outside of the transmission rod (11) is fixedly connected to a transmission assembly, the bottom of the transmission assembly is fixedly connected to a stirring assembly, the left end of the discharge barrel (10) is fixedly connected to a discharge pipe (18), the top left end of the bottom plate (1) is fixedly connected to a fixing block (19), the top of the fixing block (19) is fixedly connected to a support frame (20), the top of the support frame (20) is fixedly connected to a cylinder (21), the driving end of the cylinder (21) is fixedly connected to a mounting plate (22), the bottom of the mounting plate (22) is provided with a detection head (23), and the rear end of the discharge barrel (10) is fixedly connected to a scale.

2. A small molecule detection device according to claim 1, characterized in that: The transmission assembly comprises a driving bevel gear (12), the driving bevel gear (12) being fixedly connected to the outside of the transmission rod (11), and a driven bevel gear (13) being rotatably connected to the top of the mixing barrel (2), the driving bevel gear (12) and the driven bevel gear (13) being meshingly connected.

3. A small molecule detection device according to claim 2, characterized in that: The stirring assembly comprises a rotating rod (14), the top of the rotating rod (14) being fixedly connected to the bottom of the driven bevel gear (13), a plurality of stirring plates (15) being fixedly connected to both sides of the outside of the rotating rod (14), and the bottom of the rotating rod (14) being rotatably connected to the bottom inner wall of the mixing barrel (2).

4. A small molecule detection device according to claim 1, characterized in that: The front end of the mixing barrel (2) is fixedly connected to a connecting pipe (16), the other end of the connecting pipe (16) is fixedly connected to the front end of the discharge barrel (10), and a one-way valve (17) is provided at the top of the connecting pipe (16).

5. A small molecule detection device according to claim 1, characterized in that: Extension blocks (24) are fixedly connected to both sides of the exterior of the detection head (23), sliding columns (25) are fixedly and slidably connected to both sides of the mounting plate (22), a spring (26) is sleeved on the exterior of the sliding column (25), a limiting block (27) is fixedly connected to one side of the sliding column (25), a clamping block (28) is fixedly connected to one end of the limiting block (27) away from the sliding column (25), and the exterior of the clamping block (28) is engaged with the through hole of the extension block (24).

6. A small molecule detection device according to claim 1, characterized in that: The interior of the fixed block (19) is fixedly connected to a second motor (30), a driving end of the second motor (30) is fixedly connected to a carrier plate (31), a top of the carrier plate (31) is slidably connected to a plurality of containers (32), and the exterior of the carrier plate (31) is rotatably connected to the inner wall of the fixed block (19).

7. A small molecule detection device according to claim 5, characterized in that: The bottom of the discharge barrel (10) is fixedly connected to the top of the bottom plate (1), a slot hole (29) is provided inside the mounting plate (22), and the outside of the extension block (24) is slidably connected to the inner wall of the slot hole (29).

8. A small molecule detection device according to claim 5, characterized in that: One end of the spring (26) is fixedly connected to one side of the limiting block (27), and the other end of the spring (26) is fixedly connected to an inner wall of one side of the mounting plate (22).