Flow cell structure for concentrated PH value and conductivity detection

Abstract

The utility model provides a flow cell structure for centrally detecting the pH value and the conductivity, and solves the problems that different devices need to be used for respectively measuring the pH value and the conductivity value of liquid medicine when the pH value and the conductivity value of the liquid medicine are detected, the operation is tedious, and the measuring efficiency is low. The flow cell structure comprises a shell assembly, an electrode body and a flow cell, a liquid inlet and a liquid outlet are formed in the shell assembly, the flow cell is fixedly connected with the shell assembly, the flow cell is provided with a main flow channel and a detection flow channel which are communicated, the main flow channel is located in a cavity of the shell assembly, and the detection flow channel is located in the cavity of the shell assembly. The PH probe can extend into the detection flow channel when being fixedly connected with the flow cell; the two electrode bodies are located in the shell assembly and fixedly connected to the two opposite sides of the main flow channel, cross-flow holes are formed in the electrode bodies, and the cross-flow holes, the main flow channel, the liquid inlet and the liquid outlet are all communicated; pH and conductivity of liquid to be detected can be detected at the same time, the detection efficiency is improved, and operation is convenient; redundant runners are reduced, the structure is compact, and waste of liquid to be detected is reduced.

Description

Technical Field

[0001] The utility model relates to the technical field of biological detection, in particular to a flow cell structure for centralized pH value and conductivity detection. Background Art

[0002] In the biopharmaceutical process, a pH detection device and a conductivity detection device are often required to detect the pH value and conductivity value of the liquid online. Traditionally, the pH detection device and the conductivity detection device are separately set up as two different devices.

[0003] The working principle of the conductivity detection device is that when a voltage is applied to the two electrodes of the flow cell in the device, the anions in the solution move to the anode and the cations move to the cathode. The number of ions in the solution and the rate of ion movement determine the conductivity of the solution. The conductivity detection device measures the conductivity of the solution or the conductivity under a constant conductivity cell constant to infer the molar concentration of the electrolyte solution, thereby achieving the purpose of quantitative detection.

[0004] The pH detection device comprises a pH detection probe, which extends into a circulation pool of the detection device to continuously detect the pH of the solution.

[0005] The applicant has found that the prior art has at least the following technical problems: when detecting the pH value and conductivity value of the drug solution, different devices need to be used for measurement respectively, which is cumbersome to operate, has low measurement efficiency, and leads to waste of the drug solution. Utility Model Content

[0006] The purpose of the utility model is to provide a circulation pool structure for centralized pH value and conductivity detection, so as to solve the technical problems in the prior art that different devices need to be used to measure the pH value and conductivity value of the drug solution respectively, which is cumbersome to operate and has low measurement efficiency; the many technical effects that can be produced by the preferred technical scheme among the many technical schemes provided by the utility model are detailed as follows.

[0007] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0008] The utility model provides a flow cell structure for centralized pH value and conductivity detection, comprising a housing assembly, an electrode body and a flow cell, wherein:

[0009] The shell assembly is provided with a liquid inlet and a liquid outlet, the circulation pool is fixedly connected to the shell assembly, the circulation pool has a main flow channel and a detection flow channel that are connected, the main flow channel is located in the cavity of the shell assembly, and the pH probe can extend into the detection flow channel when it is fixedly connected to the circulation pool;

[0010] The two electrode bodies are located in the shell assembly and fixedly connected to opposite sides of the main channel. The electrode bodies are provided with through holes, and the through holes, the main channel, the liquid inlet and the liquid outlet are all connected.

[0011] Preferably, the circulation pool comprises a connecting portion and a flow channel portion, wherein:

[0012] The connecting portion and the flow channel portion are fixedly connected or are an integrally formed structure. The connecting portion is located outside the shell assembly and is used for sealingly threaded connection with the PH probe. The flow channel portion is located inside the shell assembly, and the main flow channel is formed inside the flow channel portion.

[0013] Preferably, the main channel and the through-flow hole are arranged coaxially.

[0014] Preferably, the shell assembly includes a first shell and a second shell, and the first shell and the second shell are detachably fixedly connected and enclose an inner cavity.

[0015] Preferably, both the first shell and the second shell are provided with a clearance groove, and the two clearance grooves are spliced ​​together to form a through-opening, and at least part of the circulation pool extends out of the through-opening and is sealed with the side wall of the through-opening.

[0016] Preferably, the circulation pool structure for centralized pH value and conductivity detection also includes two joints, the liquid inlet and the liquid outlet are respectively located on the two joints, and the electrode body is clamped and fixed between the corresponding joints and the side of the circulation pool; a drainage channel connected to the liquid inlet and the liquid outlet is provided on the joint, and the drainage channel is connected to the through-hole and the main channel.

[0017] Preferably, the joint includes a fixedly connected tube connection portion and a limit step, the limit step extends into the shell assembly, the tube connection portion extends out of the shell assembly from the liquid inlet or the liquid outlet, the tube connection portion is used to be detachably connected to an external pipeline, and the electrode body is clamped and fixed between the corresponding limit step and the circulation pool.

[0018] Preferably, a positioning groove is provided on one of the side of the circulation pool and the electrode body, and a positioning convex block is provided on the other of the side and the electrode body, and the positioning convex block is inserted into the positioning groove, so that the main flow channel and the through-flow hole are coaxially arranged and communicated;

[0019] And / or, between the limiting step and the electrode body, one of them is provided with a positioning groove, and the other of them is provided with a positioning protrusion, and the positioning protrusion is inserted into the positioning groove, so that the drainage channel and the through-hole are coaxially arranged and communicated.

[0020] Preferably, a gasket is further provided in the shell assembly, and the gasket is respectively provided between the circulation pool and the electrode body, or between the electrode body and the joint.

[0021] Preferably, a mounting hole is provided on the electrode body, a temperature sensor is fixed in the mounting hole, and the temperature sensor is used to detect the temperature of the solution liquid flowing through the electrode body.

[0022] The utility model provides a circulation pool structure for centralized pH value and conductivity detection, which has the following beneficial effects compared with the prior art: the liquid to be tested enters the shell component from the liquid inlet, and flows out of the shell component through the through-holes, the main flow channel, and the liquid outlet in sequence; when flowing through the through-holes of the two electrode bodies, the two electrode bodies are connected to the external detection circuit through wires for detecting the conductivity of the liquid; when flowing through the main flow channel, the pH probe can be detachably connected to the circulation pool, and can be inserted into the detection flow channel to detect the pH of the liquid; through the circulation pool structure for centralized pH value and conductivity detection, the pH and conductivity of the liquid to be tested can be detected by correspondingly fixing the electrode bodies and the pH probe, thereby improving the detection efficiency and facilitating the operation; reducing the setting of redundant flow channels, making the structure compact and reducing the waste of the liquid to be tested. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0024] Figure 1 It is a schematic diagram of the overall structure of the flow cell structure for centralized pH value and conductivity detection;

[0025] Figure 2 It is an exploded schematic diagram of the flow cell structure for centralized pH and conductivity detection;

[0026] Figure 3 It is a schematic diagram of the structure of the circulation cell;

[0027] Figure 4 It is a schematic diagram of the cross-sectional structure of the flow cell structure for centralized pH value and conductivity detection.

[0028] In the figure, 11, the first shell; 12, the second shell; 13, the liquid inlet; 14, the liquid outlet; 2, the circulation pool; 21, the flow channel; 211, the main flow channel; 22, the connecting part; 221, the detection flow channel; 23, the positioning groove; 3, the electrode body; 31, the through-hole; 32, the mounting hole; 33, the positioning protrusion; 4, the joint; 41, the pipe connecting part; 42, the limiting step; 43, the drainage channel; 5, the gasket. DETAILED DESCRIPTION

[0029] In order to make the purpose, technical solution and advantages of the utility model clearer, the technical solution of the utility model will be described in detail below. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other implementation methods obtained by ordinary technicians in this field without creative work belong to the scope of protection of the utility model.

[0030] In the description of the present invention, it should be understood that the terms "center", "length", "width", "height", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "side" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention. In the description of the present invention, unless otherwise specified, "multiple" means two or more.

[0031] In the description of the present invention, it is also necessary to explain that, unless otherwise clearly specified and limited, the terms "set", "install", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0032] The embodiment of the utility model provides a flow cell structure for centralized pH value and conductivity detection, which improves detection efficiency and facilitates operation; reduces the setting of redundant flow channels, has a compact structure, and reduces waste of liquid to be tested.

[0033] Combine the following Figure 1-Figure 4 The technical solution provided by the utility model is described in more detail.

[0034] See also Figure 1-Figure 4As shown, the utility model provides a circulation cell structure for centralized pH value and conductivity detection, including a shell assembly, an electrode body 3 and a circulation cell 2, wherein: the shell assembly is provided with a liquid inlet 13 and a liquid outlet 14, the circulation cell 2 is fixedly connected to the shell assembly, the circulation cell 2 has a main flow channel 211 and a detection flow channel 221, the main flow channel 211 is located in the cavity of the shell assembly, and the pH probe can extend into the detection flow channel 221 when it is fixedly connected to the circulation cell 2; two electrode bodies 3 are located in the shell assembly and fixedly connected to opposite sides of the main flow channel 211, and a through-flow hole 31 is provided on the electrode body 3, and the through-flow hole 31, the main flow channel 211, the liquid inlet 13 and the liquid outlet 14 are all connected.

[0035] The pH probe is fixed on a cover, which is threadedly connected to the flow cell 2 to seal the opening of the flow cell 2, and at the same time the probe extends into the detection channel 221. The pH probe is an existing mature technology, which is connected to the detection circuit wire to detect the pH value of the liquid, and its structure is not described in detail here.

[0036] The two electrode bodies 3 are connected to the external detection circuit wires for detecting the conductivity of the liquid, which belongs to the existing mature technology and will not be described in detail here.

[0037] In the circulation pool structure for centralized pH value and conductivity detection of the present embodiment, the liquid to be tested enters the shell assembly from the liquid inlet 13, and flows out of the shell assembly through the through-hole 31, the main channel 211, and the liquid outlet 14 in sequence. When flowing through the through-holes of the two electrode bodies 3, the two electrode bodies 3 are connected to the external detection circuit through wires to detect the conductivity of the liquid. When flowing through the main channel 211, the pH probe can be detachably connected to the circulation pool 2 and extended into the detection channel 221 to detect the pH of the liquid.

[0038] Through the circulation pool structure for centralized pH value and conductivity detection, the pH and conductivity of the liquid to be tested can be detected corresponding to the fixed electrode body 3 and the pH probe, thereby improving the detection efficiency and facilitating the operation; the setting of redundant flow channels is reduced, the structure is compact, and the waste of the liquid to be tested is reduced.

[0039] As an alternative embodiment, see Figure 2 and Figure 3 As shown, the circulation pool 2 includes a connecting portion 22 and a flow channel portion 21, wherein: the connecting portion 22 and the flow channel portion 21 are fixedly connected or the two are an integrally formed structure, the connecting portion 22 is located outside the shell assembly, and is used for sealing threaded connection with the pH probe; the flow channel portion 21 is located inside the shell assembly, the main channel 211 is formed in the flow channel portion 21, and the detection channel 221 is formed in the connecting portion 22.

[0040] In this embodiment, the connection part 22 and the flow channel part 21 are an integrally formed structure, and no extra connection part 22 is required, which improves the stability of the structure. The connection part 22 extends out of the housing assembly, which facilitates the detachable connection between the connection part 22 and the cover body with the pH probe, such as threaded connection, clamping, etc. The flow channel part 21 is in the inner cavity of the housing assembly, and the liquid can pass through the main flow channel 211.

[0041] See also Figure 4 As shown, the inner cavity of the connecting portion 22 is connected to the main flow channel 211. With such an arrangement, when the cover body with the pH probe is threadedly connected to the port of the connecting portion 22, the probe can extend from the inner cavity of the connecting portion 22 into the main flow channel 211, or the probe is in the detection flow channel 221, thereby detecting the pH value of the liquid.

[0042] As an alternative embodiment, see Figure 4 As shown, the main channel 211 is coaxially arranged with the through-flow hole 31, which reduces the dead angle of the liquid flow and facilitates the liquid to smoothly pass through the electrode body 3 and the flow cell 2. This structure facilitates the probe to extend from the connecting part 22 into the flow cell 2 to detect the pH value of the liquid.

[0043] As an alternative embodiment, see Figure 1 and Figure 2 As shown, the housing assembly includes a first housing 11 and a second housing 12 . The first housing 11 and the second housing 12 are detachably fixedly connected and enclose an inner cavity.

[0044] For details, see Figure 1 and Figure 2 As shown, the first shell 11 and the second shell 12 can be detachably connected by bolts and nut assemblies, or connected by snap-fitting or the like, so as to facilitate assembly and disassembly.

[0045] As an alternative embodiment, see Figure 1 , Figure 2 and Figure 4 As shown, both the first shell 11 and the second shell 12 are provided with a clearance groove, and the two clearance grooves are spliced ​​together to form a through-opening, and at least part of the flow pool 2 extends out of the through-opening and is sealed with the side wall of the through-opening.

[0046] After the first shell 11 and the second shell 12 are connected in place, the connection part 22 of the circulation pool 2 can extend out of the shell assembly through the through opening formed by the paving groove, and the paving groove is in sealing contact with the outer wall of the connection part 22 to ensure the sealing performance and prevent liquid leakage. Specifically, the paving groove and the outer wall of the connection part 22 can be sealed and connected by a sealing ring or the like.

[0047] As an alternative embodiment, see Figure 1 , Figure 2 and Figure 4As shown, the circulation pool structure for centralized pH value and conductivity detection also includes two joints 4, which are respectively fixedly connected to the liquid inlet 13 and the liquid outlet 14, and the electrode body 3 is clamped and fixed between the corresponding joints 4 and the side of the circulation pool 2; a drainage channel 43 connected to the liquid inlet 13 and the liquid outlet 14 is provided on the joint, and the drainage channel 43 is connected to the through hole 31 and the main channel 211.

[0048] The connector 4 can be connected to an external pipeline to introduce the liquid to be tested into the structure, so that the liquid can pass through the liquid inlet 13, the drainage channel 43, the through-hole 31, the main channel 211 and the liquid outlet 14 in sequence.

[0049] The end of the joint away from the electrode can be set in a barb shape, that is, the tube connection part 22 is in a barb shape, so as to be connected to an external pipeline. The tube connection part 22 can also be provided with an internal thread to facilitate matching different types of adapters and adapting to pipelines of different thicknesses, so as to be more universal.

[0050] As an alternative embodiment, see Figure 2 and Figure 4 As shown, the connector 4 includes a fixedly connected tube connection portion 41 and a limiting step 42, the limiting step 42 extends into the shell assembly, the tube connection portion 41 extends out of the shell assembly from the liquid inlet 13 or the liquid outlet 14, the tube connection portion 41 is used for detachable connection with an external pipeline, and the electrode body 3 is clamped and fixed between the corresponding limiting step 42 and the circulation pool 2.

[0051] See also Figure 2 and Figure 4 As shown, the outer diameter of the tube connection part 41 is smaller than the outer diameter of the limiting step 42. The limiting step 42 is located in the shell assembly and abuts against the inner wall of the end of the shell assembly to prevent the joint from being separated from the shell assembly and ensure the stability of the structure. The electrode body 3 is directly clamped and fixed between the limiting step 42 and the side of the circulation pool 2, without the need for an extra connection structure, thereby improving the stability of the structure.

[0052] As an alternative embodiment, see Figure 4 As shown, between the side of the flow cell 2 and the electrode body 3, one of them is provided with a positioning groove 23, and the other is provided with a positioning protrusion 33, and the positioning protrusion 33 is inserted into the positioning groove 23, so that the main flow channel 211 and the through-flow hole 31 are coaxially arranged and connected; in this embodiment, the positioning protrusion 33 is provided on the electrode body 3, and the positioning groove 23 is provided on the side of the flow cell 2; see Figure 4As shown, between the limiting step 42 and the electrode body 3, one of them is provided with a positioning groove 23, and the other is provided with a positioning protrusion 33, and the positioning protrusion 33 is inserted into the positioning groove 23, so that the drainage channel 43 is coaxially arranged and connected with the through hole 31. In this embodiment, the positioning protrusion 33 is provided on the electrode body 3, and the positioning groove 23 is provided on the limiting step 42 of the joint.

[0053] The matching structure of the positioning protrusion 33 and the positioning groove 23 can make the joint, the electrode body 3 and the main flow channel 211 of the circulation pool 2 coaxially arranged, thereby ensuring smooth liquid circulation and preventing the occurrence of dead spots for fluid flow.

[0054] As an alternative embodiment, see Figure 4 As shown, a gasket 5 is further provided in the shell assembly, and the gasket 5 is respectively provided between the circulation pool 2 and the electrode body 3, or between the electrode body 3 and the joint 4.

[0055] The above structure can ensure good sealing performance between the circulation pool 2 and the electrode body 3, or between the electrode body 3 and the joint 4, and prevent liquid from leaking out.

[0056] As an alternative embodiment, see Figure 2 As shown, the electrode body 3 is provided with a mounting hole 32, in which a temperature sensor is fixed, and the temperature sensor is used to detect the temperature of the solution liquid flowing through the electrode body 3. The temperature sensor is connected to the controller through a wire for transmitting temperature data.

[0057] In the description of this specification, specific features, structures or characteristics may be combined in an appropriate manner in any one or more embodiments or examples.

[0058] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the utility model. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, without contradiction.

[0059] The above is only a specific implementation of the utility model, but the protection scope of the utility model is not limited thereto. Any technician familiar with the technical field can easily think of changes or substitutions within the technical scope disclosed by the utility model, which should be included in the protection scope of the utility model. Therefore, the protection scope of the utility model should be based on the protection scope of the claims.

Claims

1. A flow cell structure for centralized pH value and conductivity detection, characterized in that: It includes a housing assembly, an electrode body and a flow cell, wherein: The shell assembly is provided with a liquid inlet and a liquid outlet, the circulation pool is fixedly connected to the shell assembly, the circulation pool has a main flow channel and a detection flow channel that are connected, the main flow channel is located in the cavity of the shell assembly, and the pH probe can extend into the detection flow channel when it is fixedly connected to the circulation pool; The two electrode bodies are located in the shell assembly and fixedly connected to opposite sides of the main channel. The electrode bodies are provided with through holes, and the through holes, the main channel, the liquid inlet and the liquid outlet are all connected.

2. The flow cell structure for centralized pH value and conductivity detection according to claim 1, characterized in that: The circulation pool comprises a connecting portion and a flow channel portion, wherein: The connecting portion and the flow channel portion are fixedly connected or are an integrally formed structure. The connecting portion is located outside the shell assembly and is used for sealingly threaded connection with the PH probe. The flow channel portion is located inside the shell assembly, and the main flow channel is formed inside the flow channel portion.

3. The flow cell structure for centralized pH value and conductivity detection according to claim 2, characterized in that: The main flow channel and the through-flow hole are arranged coaxially.

4. The flow cell structure for centralized pH value and conductivity detection according to claim 1, characterized in that: The shell assembly includes a first shell and a second shell. The first shell and the second shell are detachably fixedly connected and enclose an inner cavity.

5. The flow cell structure for centralized pH value and conductivity detection according to claim 4, characterized in that: The first shell and the second shell are both provided with a clearance groove, and the two clearance grooves are spliced ​​together to form a through-opening, and at least a part of the flow pool extends out of the through-opening and is sealed with the side wall of the through-opening.

6. The flow cell structure for centralized pH value and conductivity detection according to claim 1, characterized in that: The circulation pool structure for centralized pH value and conductivity detection also includes two joints, the liquid inlet and the liquid outlet are respectively located on the two joints, and the electrode body is clamped and fixed between the corresponding joints and the side of the circulation pool; the joint is provided with a drainage channel connected to the liquid inlet and the liquid outlet, and the drainage channel is connected to the through-hole and the main channel.

7. The flow cell structure for centralized pH value and conductivity detection according to claim 6, characterized in that: The joint includes a fixedly connected tube connection portion and a limiting step, wherein the limiting step extends into the shell assembly, and the tube connection portion extends out of the shell assembly from the liquid inlet or the liquid outlet, and the tube connection portion is used for detachably connecting to an external pipeline, and the electrode body is clamped and fixed between the corresponding limiting step and the circulation pool.

8. The flow cell structure for centralized pH value and conductivity detection according to claim 7, characterized in that: A positioning groove is provided on one of the side of the circulation pool and the electrode body, and a positioning convex block is provided on the other of the side of the circulation pool. The positioning convex block is inserted into the positioning groove, so that the main flow channel and the through-flow hole are coaxially arranged and communicated with each other; And / or, between the limiting step and the electrode body, one of them is provided with a positioning groove, and the other of them is provided with a positioning protrusion, and the positioning protrusion is inserted into the positioning groove, so that the drainage channel and the through-hole are coaxially arranged and communicated.

9. The flow cell structure for centralized pH value and conductivity detection according to claim 6, characterized in that: A gasket is also arranged in the shell component, and the gasket is respectively arranged between the circulation pool and the electrode body, or between the electrode body and the joint.

10. The flow cell structure for centralized pH value and conductivity detection according to claim 1, characterized in that: The electrode body is provided with a mounting hole, in which a temperature sensor is fixed, and the temperature sensor is used to detect the temperature of the solution liquid flowing through the electrode body.

Images