Stem cell storage device
By designing a stem cell storage device that includes a limiting component and a sealing component, the problem of liquid nitrogen leakage in stem cell freezing storage is solved, ensuring the storage stability of stem cells in other test tubes.
Patent Information
- Application Number
- CN202421657220.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-15
- Publication Date
- 2025-05-27
- Estimated Expiration
- 2034-07-15
AI Technical Summary
During the frozen storage of stem cells, the prior art can easily lead to liquid nitrogen leakage, affecting the storage of stem cells in other test tubes.
A stem cell storage device is designed, including a base, a rotary rod, annular shell, a circular plate, a placing cylinder, a cell test tube, a sealing plug, a limit seat, a cover plate, a limit assembly and a sealing assembly. Through the coordination of the limiting assembly and the sealing assembly, ensure that the sealing assembly automatically seals and places the bottom end of the barrel when the cell test tube is removed to prevent liquid nitrogen leakage.
It effectively prevents the leakage of liquid nitrogen when the cell test tube is removed, protects stem cells in other test tubes, and ensures the temperature stability in the storage box.
Smart Images

Figure CN222906410U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of stem cell storage, in particular to a stem cell storage device. Background Technique
[0002] Stem cells are a type of cells with unlimited or immortal self-renewal ability, and can produce at least one type of highly differentiated daughter cells. Over the years, the definition of stem cells has been continuously revised and defined from different levels. Most biologists and medical scientists believe that stem cells are a type of cells derived from embryos, fetuses, or adults with the ability of unlimited self-renewal and proliferation and differentiation under certain conditions. When stem cells are cryopreserved, generally, multiple test tubes containing stem cells are placed in a storage box, and then liquid nitrogen is filled for heat preservation. However, when taking out a certain stem cell test tube, it is easy to cause the leakage of liquid nitrogen. At this time, the temperature in the storage box will fluctuate, which will affect the storage of stem cells in other test tubes. Therefore, we propose a stem cell storage device to solve the above problems. Content of the Utility Model
[0003] (I) Technical Problems to be Solved
[0004] In view of the deficiencies of the prior art, the utility model provides a stem cell storage device, which solves the problems raised in the above background technique.
[0005] (II) Technical Solutions
[0006] The utility model specifically adopts the following technical solutions to achieve the above purposes:
[0007] A stem cell storage device includes a base. The top of the base is rotatably connected to a rotating rod through a bearing. Two annular shells are fixed on the surface of the rotating rod. Circular plates are fixed inside the through holes equally spaced at the top of the two annular shells. Placement cylinders are fixed inside the through holes opened at the top of the circular plates. Cell test tubes are placed inside the placement cylinders. Sealing plugs are tightly inserted inside the ports of the cell test tubes. Limit seats are fixed on the top of the circular plates. Limit holes are opened on both side walls of the limit seats. Covers are placed inside the sunk grooves opened at the top of the limit seats. Limit components for clamping the limit holes are arranged on the tops of the covers. Sealing components for blocking the bottom ends are arranged on the surfaces of the placement cylinders.
[0008] Further, the limiting component includes a guide seat fixed to the top of the cover plate. Two limiting blocks adapted to the limiting holes are slidably connected inside a chute opened at the top of the guide seat. One ends of the limiting blocks all slidably penetrate through the guide seat and extend to the outside thereof and are inserted into the corresponding limiting holes. The tops of the limiting blocks are all rotatably connected with connecting rods through pin shafts. The tops of the two connecting rods are rotatably connected with a moving plate through a pin shaft. A U-shaped plate is fixed to the top of the guide seat. Two first springs are fixed inside the guide seat. The other ends of the first springs are respectively fixedly connected with the corresponding limiting blocks.
[0009] Further, the sealing component includes a guide ring fixed to the surface of the placing cylinder. T-shaped rods are slidably connected inside two relief holes opened at the top of the circular plate. The tops of the T-shaped rods are all in contact with the bottom of the cover plate. The bottom ends of the two T-shaped rods slidably penetrate through the guide ring and extend to the lower part thereof and are fixed with a sealing seat. A rubber sealing block adapted to the bottom end of the placing cylinder is fixed to the top of the sealing seat. Circular blocks are fixed to the surfaces of the T-shaped rods. Second springs are fixed to the bottoms of the circular blocks. The bottom ends of the second springs are all fixedly connected with the guide ring.
[0010] Further, sealing rings are fixed inside two relief holes opened at the top of the circular plate. The T-shaped rods are respectively located inside the corresponding sealing rings.
[0011] Further, label seats are fixedly arranged on the surface of the annular shell in an annular array. Relief grooves are opened on the label seats.
[0012] Further, rotating rings are fixed to the surface of the annular shell.
[0013] (III) Beneficial effects
[0014] Compared with the prior art, the present utility model provides a stem cell storage device, which has the following beneficial effects:
[0015] In the present utility model, by arranging a base, a rotating rod, an annular shell, a circular plate, a placing cylinder, a cell test tube, a sealing plug, a limiting seat, a cover plate, a limiting component and a sealing component, during the use of this stem cell storage device, since the cell test tube is placed inside the placing cylinder for cryogenic storage and the cell test tube is protected through the cooperation of the limiting seat and the cover plate. When a certain cell test tube needs to be taken out, the cover plate at the corresponding position is operated to be separated from the limiting seat, and then it can be taken out. However, during the taking-out process, when the cover plate is taken away, the restriction on the sealing component will be released, and then the sealing component will automatically block the placing cylinder from which the cell test tube is taken out, so as to prevent the liquid nitrogen from leaking when the cell test tube is taken out, and further protect other cell test tubes from being affected. Description of the drawings
[0016] Figure 1Schematic diagram of the overall structure of the present utility model;
[0017] Figure 2 Schematic diagram of the annular shell structure of the present utility model;
[0018] Figure 3 Cross-sectional view of the placement cylinder structure of the present utility model;
[0019] Figure 4 Schematic diagram of the limit seat structure of the present utility model.
[0020] In the figure: 1, base; 2, rotating rod; 3, annular shell; 4, round plate; 5, placement cylinder; 6, cell test tube; 7, sealing plug; 8, limit seat; 9, limit hole; 10, cover plate; 11, limit assembly; 1101, guide seat; 1102, limit block; 1103, connecting rod; 1104, moving plate; 1105, U-shaped plate; 1106, first spring; 12, sealing assembly; 1201, guide ring; 1202, T-shaped rod; 1203, sealing seat; 1204, rubber sealing block; 1205, circular block; 1206, second spring; 1207, sealing ring; 13, label seat; 14, rotating ring. Specific implementation manners
[0021] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present utility model.
[0022] Embodiment
[0023] Such as Figure 1 、 Figure 2 、 Figure 3 And Figure 4As shown in the figure, a stem cell storage device proposed by an embodiment of the present utility model includes a base 1. The top of the base 1 is rotatably connected to a rotating rod 2 through a bearing. Two annular shells 3 are fixed on the surface of the rotating rod 2. Rotating rings 14 are fixed on the surfaces of the annular shells 3. When searching for the stored cell test tubes 6, it is convenient for the staff to rotate the annular shells 3. Circular plates 4 are fixed inside the through holes equidistantly opened at the tops of the two annular shells 3. Placing cylinders 5 are fixed inside the through holes opened at the tops of the circular plates 4. Cell test tubes 6 are placed inside the placing cylinders 5. Sealing plugs 7 are tightly inserted inside the ports of the cell test tubes 6. Limiting seats 8 are fixed on the tops of the circular plates 4. Limiting holes 9 are opened on both side walls of the limiting seats 8. Cover plates 10 are placed inside the sunk grooves opened at the tops of the limiting seats 8. Limiting components 11 for engaging with the limiting holes 9 are arranged on the tops of the cover plates 10. Sealing components 12 for blocking the bottoms of the placing cylinders 5 are arranged on the surfaces of the placing cylinders 5. During the use of this stem cell storage device, when a certain cell test tube 6 needs to be taken out, the annular shell 3 can be operated to rotate to find the cell test tube 6 to be taken out. Then, the corresponding limiting component 11 is operated to separate the cover plate 10 from the limiting seat 8, and then the cell test tube 6 can be taken out. However, during the process of separating the cover plate 10 from the limiting seat 8, when the cover plate 10 is taken away, the restriction on the sealing component 12 below the cell test tube 6 to be taken out will be released, and then the sealing component 12 will block the placing cylinder 5 at this place, so that liquid nitrogen will not leak when the cell test tube 6 is taken away. When liquid nitrogen needs to be added to the inside of the annular shell 3 later, just open the inlet pipe at its top for adding.
[0024] As Figure 2 and Figure 3As shown, in some embodiments, the limit assembly 11 includes a guide seat 1101 fixed to the top of the cover plate 10. Two limit blocks 1102 adapted to the limit holes 9 are slidably connected inside the chute opened at the top of the guide seat 1101. One ends of the limit blocks 1102 all slidably penetrate through the guide seat 1101 and extend to its outside and are inserted into the corresponding limit holes 9. The tops of the limit blocks 1102 are all rotatably connected to a connecting rod 1103 through a pin shaft. The tops of the two connecting rods 1103 are rotatably connected to a moving plate 1104 through a pin shaft. A U-shaped plate 1105 is fixed to the top of the guide seat 1101. Two first springs 1106 are fixed inside the guide seat 1101. The other ends of the first springs 1106 are respectively fixedly connected to the corresponding limit blocks 1102. During use, with the cooperation of the U-shaped plate 1105, the staff can push the moving plate 1104 upward. After the moving plate 1104 moves upward, it can drive the two limit blocks 1102 to move in opposite directions through the cooperation of the two connecting rods 1103. At this time, the spring will be in a compressed state when the limit blocks 1102 move in opposite directions, and the limit blocks 1102 will slide out of the limit holes 9 after moving. At this time, the cover plate 10 can be separated from the limit seat 8. When installing the cover plate 10, repeat the above operation. After the cover plate 10 is attached to the limit seat 8 and the moving plate 1104 is released, the limit blocks 1102 can be re-inserted into the limit holes 9 under the reset force of the compressed first springs 1106. At this time, the limit seat 8 and the cover plate 10 can be connected and fixed.
[0025] As Figure 2 and Figure 3As shown, in some embodiments, the sealing assembly 12 includes a guiding ring 1201 fixed on the surface of the placing cylinder 5. T-shaped rods 1202 are slidably connected inside two relief holes opened at the top of the circular plate 4. Sealing rings 1207 are fixed inside the two relief holes opened at the top of the circular plate 4. The T-shaped rods 1202 are respectively located inside the corresponding sealing rings 1207, which can enhance the tightness of the fit between the T-shaped rods 1202 and the circular plate 4, avoiding the leakage of liquid nitrogen from the gap between the two. The tops of the T-shaped rods 1202 are in contact with the bottom of the cover plate 10. The bottoms of the two T-shaped rods 1202 slidably penetrate through the guiding ring 1201 and extend to its lower side and are fixed with a sealing seat 1203. A rubber sealing block 1204 adapted to the bottom end of the placing cylinder 5 is fixed on the top of the sealing seat 1203. Circular blocks 1205 are fixed on the surfaces of the T-shaped rods 1202. Second springs 1206 are fixed to the bottoms of the circular blocks 1205. The bottoms of the second springs 1206 are fixedly connected to the guiding ring 1201. When in use, when the cover plate 10 is removed, it will release the restriction on the T-shaped rods 1202, and then under the reset force of the compressed second springs 1206, the T-shaped rods 1202 can be driven to move upward through the circular blocks 1205. After the T-shaped rods 1202 move upward, they will drive the sealing seat 1203 to move upward. After the sealing seat 1203 moves upward, it can drive the rubber sealing block 1204 to block the bottom end of the placing cylinder 5, thereby preventing the leakage of liquid nitrogen after the cell test tube 6 is removed. When the cover plate 10 is installed, at this time, the rubber sealing block 1204 can release the blocking restriction on the bottom end of the placing cylinder 5.
[0026] As Figure 1 and Figure 2 As shown, in some embodiments, label seats 13 are fixedly arranged on the surface of the annular shell 3 in an annular array. Relief grooves are opened on the label seats 13. The provided label seats 13 are used for the staff to annotate the placed cell test tube 6, and the relief grooves opened on the label seats 13 facilitate the staff to take the annotation label paper.
[0027] Finally, it should be noted that the above are only the preferred embodiments of the present invention and are not used to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, for those skilled in the art, they can still modify the technical solutions described in the foregoing embodiments, or perform equivalent replacements for some of the technical features. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.
Claims
1. A stem cell storage device, comprising a base (1), characterized in that: The top of the base (1) is rotatably connected to a rotating rod (2) via a bearing, two annular shells (3) are fixed on the surface of the rotating rod (2), circular plates (4) are fixed inside the through holes equidistantly opened on the tops of the two annular shells (3), a placement tube (5) is fixed inside the through holes opened on the tops of the circular plates (4), a cell test tube (6) is placed inside the placement tube (5), a sealing plug (7) is tightly inserted inside the port of the cell test tube (6), a limiting seat (8) is fixed on the top of the circular plates (4), limiting holes (9) are opened on both side walls of the limiting seat (8), a cover plate (10) is placed inside the sink groove opened on the top of the limiting seat (8), a limiting component (11) for engaging the limiting hole (9) is arranged on the top of the cover plate (10), and a sealing component (12) for sealing the bottom end of the placement tube (5) is arranged on the surface of the placement tube (5).
2. A stem cell storage device according to claim 1, characterized in that: The limiting assembly (11) comprises a guide seat (1101) fixed on the top of the cover plate (10); two limiting blocks (1102) adapted to the limiting holes (9) are slidably connected inside a slide groove opened on the top of the guide seat (1101); one end of each limiting block (1102) slides through the guide seat (1101) to extend to the outside thereof and is plugged into the inside of the corresponding limiting hole (9); the top of each limiting block (1102) is rotatably connected to a connecting rod (1103) via a pin shaft; the top ends of the two connecting rods (1103) are rotatably connected to a moving plate (1104) via a pin shaft; a U-shaped plate (1105) is fixed on the top of the guide seat (1101); two springs (1106) are fixed inside the guide seat (1101); the other ends of each spring (1106) are fixedly connected to the corresponding limiting blocks (1102).
3. A stem cell storage device according to claim 1, characterized in that: The sealing assembly (12) comprises a guide ring (1201) fixed on the surface of the placement cylinder (5); two clearance holes opened on the top of the circular plate (4) are slidably connected to the inside of which are T-shaped rods (1202); the top ends of the T-shaped rods (1202) are in contact with the bottom of the cover plate (10); the bottom ends of the two T-shaped rods (1202) slide through the guide ring (1201) and extend to the bottom thereof and are fixed with a sealing seat (1203); a rubber sealing block (1204) adapted to the bottom end of the placement cylinder (5) is fixed on the top of the sealing seat (1203); a circular block (1205) is fixed on the surface of the T-shaped rod (1202); a spring 2 (1206) is fixed on the bottom of the circular block (1205); and the bottom end of the spring 2 (1206) is fixedly connected to the guide ring (1201).
4. A stem cell storage device according to claim 3, characterized in that: Sealing rings (1207) are fixed inside the two clearance holes opened on the top of the circular plate (4), and the T-shaped rods (1202) are respectively located inside the corresponding sealing rings (1207).
5. A stem cell storage device according to claim 1, characterized in that: The surface of the annular shell (3) is fixed with label seats (13) in an annular array, and the label seats (13) are provided with clearance grooves.
6. A stem cell storage device according to claim 1, characterized in that: A rotating ring (14) is fixed on the surface of the annular shell (3).