Dry powder cell culture medium raw material double-column hopper mixer

Abstract

The utility model relates to a dry powder cell culture medium raw material double-column type hopper mixer which is characterized by comprising a hopper elevator, a mixing hopper and a feeding hopper, the mixing hopper is fixed in a first support, the first support is detachably installed in a connecting frame, the connecting frame is connected with the hopper elevator, and the feeding hopper is connected with the hopper elevator. Telescopic walking wheel assemblies and supporting legs are arranged at the bottom of the first support, the feeding hopper is fixed to the translation frame through supporting columns, second walking wheels are arranged at the bottom of the translation frame, and the feeding hopper is conveyed to the position under the mixing hopper through the second walking wheels; the bottom of the feeding hopper is connected with a first connecting flange through a corrugated pipe, a second connecting flange is installed at a discharging port in the bottom of the mixing hopper, and the first connecting flange is detachably connected with the second connecting flange. The design has the advantages of being simple in structure, easy to manufacture, practical and efficient.

Description

Technical Field

[0001] The utility model relates to the technical field of cell culture, in particular to a double-column hopper mixer for raw materials of dry powder cell culture medium. Background Art

[0002] Cell culture medium is one of the core raw materials of biomedicine, and its performance can directly affect the level of output, and then affect the production efficiency and production cost of biopharmaceuticals. The culture medium formula generally contains dozens or hundreds of different chemical components including sugars, amino acids, inorganic salts, vitamins, trace elements, growth factors, etc. The raw materials of each component need to be mixed during the production process, and a hopper mixer is required at this time. However, the existing hopper mixer often only has the function of mixing materials, and the discharge is very troublesome. In the actual production process, a vacuum negative pressure pipeline transportation method is often used, which has great limitations. Due to the need for vacuuming, the hopper often adopts a fixed structure and cannot be moved. Therefore, after each processing, the cleaning of the hopper and other structures is cumbersome and time-consuming, which increases the production cost, and it is not easy to clean thoroughly. In addition, vacuuming has high requirements for the sealing of the hopper, and problems are easy to occur during the production process. However, the raw materials of the culture medium components are multi-component and complex, and the content accuracy requirements are high. The hopper needs to be thoroughly cleaned. Therefore, in order to solve the above problems, a double-column hopper mixer for dry powder cell culture medium raw materials is particularly important. Summary of the invention

[0003] In order to solve the above problems, the utility model designs a double-column hopper mixer for dry powder cell culture medium raw materials. The first bracket is connected to the hopper elevator through a connecting frame. After the processing is completed, the mixing hopper can be disassembled from the hopper elevator, and the mixing hopper can be transported out through the telescopic walking wheel assembly for separate cleaning. This method not only facilitates cleaning, but also ensures the cleanliness after cleaning, thereby increasing the practical performance.

[0004] In order to solve the above-mentioned technical problems, the utility model provides a double-column hopper mixer for dry powder cell culture medium raw materials, characterized in that it includes a hopper elevator, a mixing hopper and a feeding hopper, the mixing hopper is fixed in a first bracket, the first bracket is detachably installed in a connecting frame, the connecting frame is connected to the hopper elevator, a telescopic walking wheel assembly and a support leg are provided at the bottom of the first bracket, the feeding hopper is fixed on the translation frame through a supporting column, a second walking wheel is provided at the bottom of the translation frame, the feeding hopper is transported to the bottom of the mixing hopper by the second walking wheel, the bottom of the feeding hopper is connected to the first connecting flange through a bellows, the discharge port at the bottom of the mixing hopper is installed with a second connecting flange, and the first connecting flange and the second connecting flange are detachably connected.

[0005] Further: the first bracket includes a lower bracket, an upper bracket and an auxiliary bracket, the upper bracket is connected to the top of the lower bracket through a first support rod, the auxiliary bracket is located between the upper bracket and the lower bracket and is fixedly connected to the lower bracket through a second support rod, the mixing hopper is composed of an upper cylinder and a lower cone connected together, the upper cylinder is rotatably connected to the upper bracket through a first bearing arranged on the outer wall, the lower cone is rotatably connected to the auxiliary bracket through a second bearing arranged on the outer wall, the upper bracket extends into the connecting frame, the connecting frame is detachably connected to the upper bracket through a connecting piece, and the connecting piece is connected to the upper bracket through a bolt assembly.

[0006] Furthermore: a first gear is sleeved on the lower end of the second bearing, the first gear and the second gear are meshed with each other, the second gear is sleeved and fixed on the output shaft of the rotating motor, and the rotating motor is installed on the auxiliary bracket.

[0007] Furthermore: a supporting leg is respectively arranged at the four corners of the bottom of the lower bracket, a connecting plate is respectively arranged on the left and right sides of the lower bracket, the connecting plate is connected to the lower bracket as a whole, and the telescopic walking wheel assembly is installed on the connecting plate.

[0008] Furthermore: the telescopic walking wheel assembly includes a first walking wheel, a guide column, a spring and a connecting cylinder, the upper end of the connecting cylinder is sealed, the connecting cylinder is fixed on the connecting plate and has a guide hole matching the guide column at the bottom, a through hole is also provided on the connecting plate at a position relative to the guide hole, the first walking wheel is installed at the lower end of the guide column, the upper end of the guide column passes through the through hole and extends into the guide hole and is connected to it by a spring.

[0009] Furthermore: the hopper elevator includes a left column, a right column, a left lifting seat and a right lifting seat, the connecting frame is fixed between the left lifting seat and the right lifting seat, a first lifting electric cylinder is installed in the left column, one end of the left lifting seat extends into the left column and is connected to the first lifting electric cylinder, a first through groove for lifting the left lifting seat is opened on the right side of the left column, a second lifting electric cylinder is installed in the right column, one end of the right lifting seat extends into the right column and is connected to the second lifting electric cylinder, and a second through groove for lifting the right lifting seat is opened on the left side of the right column.

[0010] After adopting the above structure, the utility model connects the first bracket to the hopper elevator through the connecting frame. After the processing is completed, the mixing hopper can be disassembled from the hopper elevator, so that the mixing hopper can be transported out for separate cleaning through the telescopic walking wheel assembly. This method not only facilitates cleaning, but also ensures the cleanliness after cleaning, which plays a role in increasing practical performance; and the present design also has the advantages of simple structure, easy manufacturing, practicality and high efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0011] The utility model is further described in detail below in conjunction with the accompanying drawings and specific implementation methods.

[0012] Figure 1 It is a structural schematic diagram of the utility model.

[0013] Figure 2 for Figure 1 A is an enlarged view of the middle image.

[0014] Figure 3 This is a structural diagram of the first bracket.

[0015] Figure 4 for Figure 3 Enlarged view of B. DETAILED DESCRIPTION

[0016] like Figure 1 and Figure 2 A double-column hopper mixer for dry powder cell culture medium raw materials is shown, including a hopper elevator, a mixing hopper 6 and a feeding hopper 7, wherein the mixing hopper is fixed in a first bracket, and the first bracket is detachably mounted in a connecting frame 5, and the connecting frame is connected to the hopper elevator, and a telescopic walking wheel assembly and a supporting leg 18 are provided at the bottom of the first bracket, and the feeding hopper is fixed to a translation frame 8 through a supporting column, and a second walking wheel is provided at the bottom of the translation frame, and the feeding hopper is transported to the bottom of the mixing hopper by the second walking wheel, and the bottom of the feeding hopper is connected to a first connecting flange 19 through a bellows 20, and a second connecting flange 13 is installed at the discharge port at the bottom of the mixing hopper, and the first connecting flange and the second connecting flange are detachably connected.

[0017] like Figure 3 The first bracket shown includes a lower bracket 10, an upper bracket 9 and an auxiliary bracket 21, the upper bracket is connected to the top of the lower bracket through a first support rod, the auxiliary bracket is located between the upper bracket and the lower bracket and is fixedly connected to the lower bracket through a second support rod, the mixing hopper is composed of an upper cylinder 6-1 and a lower cone 6-2 connected together from top to bottom, the upper cylinder is rotatably connected to the upper bracket through a first bearing 12 arranged on the outer wall, the lower cone is rotatably connected to the auxiliary bracket through a second bearing 22 arranged on the outer wall, the upper bracket extends into the connecting frame, the connecting frame is detachably connected to the upper bracket through a connecting piece, and the connecting piece is connected to the upper bracket through a bolt assembly.

[0018] like Figure 4The lower end of the second bearing is sleeved with a first gear 23, the first gear and the second gear 24 are meshed with each other, the second gear is sleeved and fixed on the output shaft of the rotating motor 25, and the rotating motor is installed on the auxiliary bracket.

[0019] like Figure 3 A supporting leg is provided at each of the four corners at the bottom of the lower bracket, and a connecting plate 14 is provided at each of the left and right sides of the lower bracket. The connecting plate is connected to the lower bracket as a whole, and the telescopic walking wheel assembly is installed on the connecting plate.

[0020] like Figure 3 The telescopic wheel assembly shown includes a first wheel 15, a guide post 17, a spring and a connecting cylinder 16. The upper end of the connecting cylinder is sealed. The connecting cylinder is fixed on a connecting plate and has a guide hole matching the guide post at its bottom. A through hole is also provided on the connecting plate at a position relative to the guide hole. The first wheel is mounted on the lower end of the guide post. The upper end of the guide post extends into the guide hole through the through hole and is connected to the guide hole through the spring. When the mixing hopper is not filled with raw materials or after the material is discharged, the spring uses the first wheel to lift the first bracket. At this time, the mixing hopper can be transported by the first wheel. When the mixing hopper is filled with raw materials, the spring is contracted by force, and the support legs are in contact with the ground and are not easy to move.

[0021] like Figure 1 The hopper elevator shown includes a left column 1, a right column 2, a left lifting seat 4 and a right lifting seat 3. The connecting frame is fixed between the left lifting seat and the right lifting seat. A first lifting electric cylinder is installed in the left column. One end of the left lifting seat extends into the left column and is connected to the first lifting electric cylinder. A first through groove for lifting the left lifting seat is provided on the right side of the left column. A second lifting electric cylinder is installed in the right column. One end of the right lifting seat extends into the right column and is connected to the second lifting electric cylinder. A second through groove for lifting the right lifting seat is provided on the left side of the right column.

[0022] When working, first start the rotating motor to rotate the mixing hopper to complete the mixing of the raw materials in the mixing hopper. After the mixing is completed, start the hopper elevator to lift the mixing hopper, move the feeding hopper to the bottom of the mixing hopper, and automatically discharge the materials by gravity.

[0023] To sum up, the utility model connects the first bracket to the hopper elevator through a connecting frame. After processing, the mixing hopper can be removed from the hopper elevator, and the mixing hopper can be transported out for separate cleaning through the telescopic walking wheel assembly. This method not only facilitates cleaning, but also ensures the cleanliness after cleaning, which plays a role in increasing practical performance; and the present design also has the advantages of simple structure, easy manufacturing, practicality and high efficiency.

[0024] The above are only preferred implementations of the utility model. The protection scope of the utility model is not limited to the above embodiments. All technical solutions under the idea of ​​the utility model belong to the protection scope of the utility model. It should be pointed out that for ordinary technicians in this technical field, some improvements and modifications without departing from the principle of the utility model should be regarded as the protection scope of the utility model.

Claims

1. A double-column hopper mixer for dry powder cell culture medium raw materials, characterized in that: It includes a hopper elevator, a mixing hopper (6) and a feeding hopper (7), wherein the mixing hopper is fixed in a first bracket, the first bracket is detachably mounted in a connecting frame (5), the connecting frame is connected to the hopper elevator, a telescopic walking wheel assembly and a supporting leg (18) are arranged at the bottom of the first bracket, the feeding hopper is fixed on a translation frame (8) through a supporting column, a second walking wheel is arranged at the bottom of the translation frame, the feeding hopper is transported to the bottom of the mixing hopper through the second walking wheel, the bottom of the feeding hopper is connected to a first connecting flange (19) through a bellows (20), a second connecting flange (13) is installed at the discharge port at the bottom of the mixing hopper, and the first connecting flange and the second connecting flange are detachably connected.

2. A double-column hopper mixer for dry powder cell culture medium raw materials according to claim 1, characterized in that: The first bracket comprises a lower bracket (10), an upper bracket (9) and an auxiliary bracket (21), the upper bracket is connected to the upper part of the lower bracket via a first support rod, the auxiliary bracket is located between the upper bracket and the lower bracket and is fixedly connected to the lower bracket via a second support rod, the mixing hopper is composed of an upper cylinder (6-1) and a lower cone (6-2) connected together from top to bottom, the upper cylinder is rotatably connected to the upper bracket via a first bearing (12) arranged on the outer wall, the lower cone is rotatably connected to the auxiliary bracket via a second bearing (22) arranged on the outer wall, the upper bracket extends into the connecting frame, the connecting frame is detachably connected to the upper bracket via a connecting piece, and the connecting piece is connected to the upper bracket via a bolt assembly.

3. A double-column hopper mixer for dry powder cell culture medium raw materials according to claim 2, characterized in that: A first gear (23) is sleeved on the lower end of the second bearing. The first gear and the second gear (24) are meshed with each other. The second gear is sleeved and fixed on the output shaft of the rotating motor (25). The rotating motor is installed on the auxiliary bracket.

4. A double-column hopper mixer for dry powder cell culture medium raw materials according to claim 2, characterized in that: A supporting leg is provided at each of the four corners at the bottom of the lower bracket, and a connecting plate (14) is provided at each of the left and right sides of the lower bracket. The connecting plate is connected to the lower bracket as a whole, and the telescopic walking wheel assembly is installed on the connecting plate.

5. A double-column hopper mixer for dry powder cell culture medium raw materials according to claim 4, characterized in that: The telescopic walking wheel assembly comprises a first walking wheel (15), a guide column (17), a spring and a connecting cylinder (16), the upper end of the connecting cylinder is sealed, the connecting cylinder is fixed on a connecting plate and a guide hole matching the guide column is formed at the bottom thereof, a through hole is also formed on the connecting plate at a position relative to the guide hole, the first walking wheel is mounted on the lower end of the guide column, the upper end of the guide column passes through the through hole and extends into the guide hole and is connected to the guide hole via a spring.

6. A double-column hopper mixer for dry powder cell culture medium raw materials according to claim 1, characterized in that: The hopper elevator comprises a left column (1), a right column (2), a left lifting seat (4) and a right lifting seat (3); the connecting frame is fixed between the left lifting seat and the right lifting seat; a first lifting electric cylinder is installed in the left column; one end of the left lifting seat extends into the left column and is connected to the first lifting electric cylinder; a first through slot for lifting the left lifting seat is provided on the right side of the left column; a second lifting electric cylinder is installed in the right column; one end of the right lifting seat extends into the right column and is connected to the second lifting electric cylinder; a second through slot for lifting the right lifting seat is provided on the left side of the right column.

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