Cleaning system of cell culture medium raw material mixing and grinding equipment
By designing a cleaning system containing purified water recovery pipelines and recycling pipelines, the problem of waste and incomplete cleaning of resources in the production of dry powder cell culture media is solved, and resource conservation and cleaning effect are improved.
Patent Information
- Application Number
- CN202421462877.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-25
- Publication Date
- 2025-06-06
- Estimated Expiration
- 2034-06-25
AI Technical Summary
During the dry powder cell culture medium production process, existing cleaning devices require rinsing or rinsing with large amounts of purified water, resulting in waste of resources and difficulty in thorough cleaning of grinding and mixing devices, which may lead to bacterial contamination.
A cleaning system including purified water recovery pipeline and circulation pipeline is designed. By setting up multiple cleaning tanks, grinders and mixing tanks, and connecting multiple valves and pipelines, the recycling and reuse of purified water is realized, self-cleaning, disinfectant rinsing and purified water rinsing is carried out.
By recycling and reuse of purified water, resources are saved and costs are reduced. At the same time, the device is thoroughly cleaned through various cleaning methods, avoiding bacterial contamination and improving the cleaning effect.
Smart Images

Figure CN222944142U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to a cleaning system, in particular to a cleaning system of a mixing and grinding device for producing a cell culture medium. Background Art
[0002] In the production process of dry powder cell culture medium, it is first necessary to grind each component raw material, and then mix the ground raw materials. Grinding and mixing are the most important procedures in production, and the quality of grinding and mixing determines the quality of the culture medium product. Two grinding devices and a mixing device are required for grinding and mixing. There will often be residues inside the grinding device and the mixing device after use, so they need to be cleaned. Existing cleaning devices generally use purified water flushing or rinsing for cleaning. In order to thoroughly clean the grinding device and the mixing device and avoid residual growth bacteria from contaminating the culture medium product, a large amount of purified water is required for flushing or rinsing. The purified water used for cleaning is often discharged directly, resulting in a huge waste of resources. Summary of the invention
[0003] In order to solve the above problems, the utility model designs a cleaning system for a cell culture medium raw material mixing and grinding equipment. Through the provided purified water recovery pipeline and circulation pipeline, part of the used purified water can be recovered and reused, which plays a role in saving resources and reducing costs.
[0004] In order to solve the above technical problems, the utility model provides a cleaning system for a cell culture medium raw material mixing and grinding equipment, characterized in that it comprises a purified water supply tank, a first cleaning tank, a second cleaning tank, a first grinder, a second grinder and a mixing tank, wherein the purified water supply tank is connected to a first three-way switch valve through a first delivery pipeline, the first three-way switch valve is respectively connected to the first cleaning tank and the second cleaning tank through auxiliary pipelines, the second cleaning tank is also connected to a disinfectant storage tank through a second delivery pipeline, the liquid outlet of the first cleaning tank and the liquid outlet of the second cleaning tank are both connected to a first four-way switch valve, the first four-way switch valve is connected to a purified water recovery pipeline, the first four-way switch valve is connected to the second four-way switch valve through a third delivery pipeline, the second four-way switch valve is connected to a first flushing pipeline in the first grinder and the second grinder through a fourth delivery pipeline, the liquid outlet of the first grinder and the liquid outlet of the second grinder are both connected to a second flushing pipeline in the mixing tank through a diversion pipeline, the liquid outlet at the bottom of the mixing tank is connected to the second three-way switch valve through a fifth delivery pipeline, and the second three-way switch valve is connected to a waste liquid discharge pipeline.
[0005] Further: the second four-way switch valve is connected to the first rinse pipeline in the first grinder, the second rinse pipeline in the second grinder and the third rinse pipeline in the mixing tank respectively through the sixth delivery pipeline.
[0006] Furthermore: an electric heating wire and a first temperature sensor are arranged in the first cleaning tank, and an agitator is also arranged in the second cleaning tank.
[0007] Furthermore: the second three-way switch valve is also connected to the first delivery pipeline through a circulation pipeline.
[0008] Furthermore: the second four-way switch valve is also connected to the fourth delivery pipeline through the seventh delivery pipeline, and the seventh delivery pipeline passes through the heat exchanger. A cavity for filling a heat exchange medium is opened in the heat exchanger, and a second temperature sensor and an electric heating tube are installed in the cavity.
[0009] After adopting the above structure, the present invention can recycle and reuse part of the used purified water through the set purified water recovery pipeline and circulation pipeline, which plays a role in saving resources and reducing costs; and after adopting the above structure, the present invention can not only use purified water for flushing, but also can perform self-cleaning before cleaning, and can perform disinfectant flushing and purified water rinsing, which improves the cleaning effect and ensures that there will be no material residue in the first grinder, the second grinder and the mixing tank, which plays a role in increasing practical performance. BRIEF DESCRIPTION OF THE DRAWINGS
[0010] The utility model is further described in detail below in conjunction with the accompanying drawings and specific implementation methods.
[0011] Figure 1 It is a structural schematic diagram of the utility model. DETAILED DESCRIPTION
[0012] like Figure 1The cleaning system of a cell culture medium raw material mixing and grinding equipment shown in the figure comprises a purified water supply tank, a first cleaning tank 3, a second cleaning tank 4, a first grinder 14, a second grinder 15 and a mixing tank 18, wherein the purified water supply tank is connected to a first three-way switch valve 2 through a first delivery pipeline 1, the first three-way switch valve is connected to the first cleaning tank and the second cleaning tank respectively through auxiliary pipelines, the second cleaning tank is also connected to a disinfectant storage tank through a second delivery pipeline 5, the liquid outlet of the first cleaning tank and the liquid outlet of the second cleaning tank are both connected to a first four-way switch valve 8, and the first four-way switch valve is connected to a purified water recovery tank. The first four-way switch valve is connected to the second four-way switch valve 10 through the third delivery pipe, the second four-way switch valve is connected to the first flushing pipe in the first grinder 14 and the second grinder 15 through the fourth delivery pipe 13, the liquid outlet of the first grinder and the liquid outlet of the second grinder are connected to the second flushing pipe in the mixing tank through the diversion pipe, the liquid outlet at the bottom of the mixing tank is connected to the second three-way switch valve 21 through the fifth delivery pipe 20, the second three-way switch valve is connected to the waste liquid discharge pipe, and the second three-way switch valve is also connected to the first delivery pipe through the circulation pipe 23.
[0013] like Figure 1 The second four-way switch valve shown is connected to the first rinse pipeline 16 in the first grinder, the second rinse pipeline 17 in the second grinder and the third rinse pipeline 19 in the mixing tank through the sixth delivery pipeline 11.
[0014] The first cleaning tank is provided with an electric heating wire and a first temperature sensor, and the second cleaning tank is also provided with a stirrer.
[0015] like Figure 1 The second four-way switch valve 10 shown is also connected to the fourth delivery pipeline through the seventh delivery pipeline 9. The seventh delivery pipeline passes through the heat exchanger 12. The heat exchanger has a cavity for filling the heat exchange medium. The second temperature sensor and the electric heating tube are installed in the cavity.
[0016] During operation, the first three-way switch valve is first controlled to connect the first delivery pipeline with the first cleaning tank and the second cleaning tank in sequence, and the first four-way switch valve is connected to the purified water recovery pipeline, the first cleaning tank and the second cleaning tank are self-cleaned by purified water, and the first cleaning tank and the second cleaning tank are filled with purified water for cleaning; then the connection between the first delivery pipeline and the second cleaning tank is closed, and the first four-way switch valve is connected to the second four-way switch valve, and the second four-way switch valve is connected to the fourth delivery pipeline, and the first grinder and the second grinder are flushed through the first flushing pipeline in the first grinder and the second grinder, and the purified water after flushing in the first grinder and the second grinder flows into the mixing tank again, and the second flushing pipeline is used to continue flushing, and the waste water after flushing is discharged through the waste liquid discharge pipeline; after flushing, the second three-way switch valve is controlled to connect the fifth delivery pipeline with the circulation pipeline, and the purified water for cleaning in the first cleaning tank is heated by the electric heating wire and the first temperature sensor, and the purified water for cleaning in the first cleaning tank is continued to flow after the temperature reaches the requirement. Purified water is used for circulating flushing; disinfectant is then added to the second cleaning tank through the second delivery pipeline, the disinfectant is mixed with the purified water in the second cleaning tank by the agitator, the first four-way switch valve is controlled to connect the second cleaning tank with it, the second four-way switch valve is connected to the fourth delivery pipeline through the seventh delivery pipeline, the mixed liquid of the disinfectant and purified water is heated by the heat exchanger and then circulated and disinfected and cleaned the first grinder, the second grinder and the mixing tank through the first flushing pipeline and the second flushing pipeline; after the disinfection and cleaning is completed, the first four-way switch valve is controlled to continue to be connected to the first cleaning tank, the second four-way switch valve is connected to the sixth delivery pipeline, and the first grinder, the second grinder and the mixing tank are rinsed respectively through the rinsing pipeline; after the rinsing is completed, the first three-way switch valve is continued to be controlled to connect the first delivery pipeline with the first cleaning tank and the second cleaning tank in sequence, and the first four-way switch valve is connected to the purified water recovery pipeline, and the first cleaning tank and the second cleaning tank are self-cleaned again with purified water.
[0017] The present invention can recycle and reuse part of the used purified water by setting up the purified water recovery pipeline and the circulation pipeline, which plays a role in saving resources and reducing costs; and after adopting the above structure, the present invention can not only use purified water for flushing, but also can use disinfectant flushing and purified water rinsing, which improves the cleaning effect and ensures that there will be no material residue in the first grinder, the second grinder and the mixing tank, which plays a role in increasing practical performance.
[0018] The above are only preferred implementations of the utility model. The protection scope of the utility model is not limited to the above embodiments. All technical solutions under the idea of the utility model belong to the protection scope of the utility model. It should be pointed out that for ordinary technicians in this technical field, some improvements and modifications without departing from the principle of the utility model should be regarded as the protection scope of the utility model.
Claims
1. A cleaning system for a cell culture medium raw material mixing and grinding device, characterized in that: The invention comprises a purified water supply tank, a first cleaning tank (3), a second cleaning tank (4), a first grinder (14), a second grinder (15) and a mixing tank (18), wherein the purified water supply tank is connected to a first three-way switch valve (2) via a first delivery pipeline (1), the first three-way switch valve is connected to the first cleaning tank and the second cleaning tank respectively via auxiliary pipelines, the second cleaning tank is also connected to a disinfectant storage tank via a second delivery pipeline (5), the liquid outlet of the first cleaning tank and the liquid outlet of the second cleaning tank are both connected to a first four-way switch valve (8), the first four-way switch valve is connected to the purified water supply tank, The first four-way switch valve is connected to the chemical water recovery pipeline (24), the first four-way switch valve is connected to the second four-way switch valve (10) through the third delivery pipeline, the second four-way switch valve is connected to the first grinder (14) and the first flushing pipeline in the second grinder (15) through the fourth delivery pipeline (13), the liquid outlet of the first grinder and the liquid outlet of the second grinder are connected to the second flushing pipeline in the mixing tank through the diversion pipeline, the liquid outlet at the bottom of the mixing tank is connected to the second three-way switch valve (21) through the fifth delivery pipeline, and the second three-way switch valve is connected to the waste liquid discharge pipeline.
2. The cleaning system for the cell culture medium raw material mixing and grinding equipment according to claim 1, characterized in that: The second four-way switch valve is connected to the first rinse pipeline (16) in the first grinder, the second rinse pipeline (17) in the second grinder and the third rinse pipeline (19) in the mixing tank respectively through the sixth delivery pipeline (11).
3. The cleaning system for the cell culture medium raw material mixing and grinding equipment according to claim 1, characterized in that: The first cleaning tank is provided with an electric heating wire and a first temperature sensor, and the second cleaning tank is also provided with a stirrer.
4. The cleaning system for the cell culture medium raw material mixing and grinding equipment according to claim 1, characterized in that: The second three-way switch valve is also connected to the first delivery pipeline via a circulation pipeline (23).
5. The cleaning system for the cell culture medium raw material mixing and grinding equipment according to claim 1, characterized in that: The second four-way switch valve (10) is also connected to the fourth delivery pipeline via a seventh delivery pipeline (9), and the seventh delivery pipeline passes through a heat exchanger (12). A cavity for filling a heat exchange medium is provided in the heat exchanger, and a second temperature sensor and an electric heating tube are installed in the cavity.