Centrifugal tube cooling structure and exhaled gas condensate collecting device
By designing a centrifugal tube cooling structure with a thermal conduction module with a heating sheet and a cooling sheet, the problem of poor cooling effect of traditional devices is solved, and efficient temperature control and condensation collection effect is achieved.
Patent Information
- Application Number
- CN202421804417.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-26
- Publication Date
- 2025-06-10
- Estimated Expiration
- 2034-07-26
AI Technical Summary
The cooling structure of the traditional exhaled air condensate collection device has poor cooling effect, and the temperature control accuracy and cooling rate have not achieved good condensation and collection effects.
A centrifugal tube cooling structure is designed, including a thermal conductivity module. A placement groove is provided on the top of the thermal conductivity module, and the heating sheet and the cooling sheet are respectively attached to both sides, and an insulation layer and hollow area are provided. Through the temperature control structure of hot and cold control, accurate and fast temperature control is achieved.
It realizes efficient cooling of centrifuge tubes, and can accurately and quickly control the temperature within a specific temperature range, such as -10°C or -20°C, which improves the condensation collection effect and reduces the maintenance requirements of the structure.
Smart Images
Figure CN222956427U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of medical devices, in particular to a centrifuge tube cooling structure and an exhaled gas condensate collection device. Background Art
[0002] In recent years, detecting the health status of subjects through the detection of exhaled breath condensate (EBC) has been a rapidly developing technical method in biomedical basic research and clinical applications.
[0003] Like blood, sweat, urine, and saliva, EBC is an important specimen source for detecting pathogens and biomarkers of respiratory diseases. The respiratory tract lining fluid contains a large number of volatile and non-volatile substances, and the changes in these substances can reflect the changes in the respiratory tract internal environment such as oxidative damage and inflammatory reactions, thus can be used to detect the changes of diseases.
[0004] Traditional exhaled gas condensate collection devices are connected to centrifuge tubes, and actively cool down at the centrifuge tube to form a local condensation environment. However, the cooling structure of traditional collection devices has poor refrigeration effect, and the temperature control accuracy and refrigeration rate fail to achieve a good condensation collection effect. Summary of the Utility Model
[0005] To overcome the problems existing in the related art, the purpose of the utility model is to provide a centrifuge tube cooling structure and an exhaled gas condensate collection device.
[0006] In a first aspect, the present application provides a centrifuge tube cooling structure, including a heat conduction module;
[0007] A placement groove for fitting and placing a centrifuge tube is provided at the top of the heat conduction module, a heating sheet is fitted on one side of the heat conduction module, and a cooling sheet is fitted on the other side of the heat conduction module;
[0008] A heat insulation layer is provided on the outer periphery of the heat conduction module, a hollow area is provided between the heat conduction module and the bottom heat insulation layer, and a through hole communicating with the hollow area is provided in the placement groove.
[0009] In one embodiment, a heating groove is provided on one side of the heat conduction module, a cooling protrusion is provided on the other side opposite to the side where the heating groove is located, the heating sheet is arranged in the heating groove, and the cooling sheet is attached to the cooling protrusion.
[0010] In one embodiment, the heat insulation layer includes a first heat insulation layer and a U-shaped heat insulation layer. The first heat insulation layer is disposed outside the heating sheet, the heat conduction module is disposed inside the U-shaped heat insulation layer, two sides of the U-shaped heat insulation layer are attached to two sides of the heat conduction module, and the hollowed-out area is disposed between the heat conduction module and the U-shaped heat insulation layer.
[0011] In one embodiment, the heat insulation layer further includes a second heat insulation layer. The second heat insulation layer is disposed between the first heat insulation layer and the heating sheet, and a hollowed-out layer is further disposed between the second heat insulation layer and the first heat insulation layer.
[0012] In one embodiment, a graphite sheet is further disposed between the second heat insulation layer and the heating sheet, and the side surface of the graphite sheet is attached to the side surfaces of the heating sheet and the heat conduction module.
[0013] In one embodiment, the heat insulation layer includes a third heat insulation layer and a fourth heat insulation layer. The third heat insulation layer and the fourth heat insulation layer are sequentially disposed outside the side surface of the heat conduction module where the refrigerating protrusions are located; the third heat insulation layer is attached to the side surface of the heat conduction module, the refrigerating protrusions pass through the third heat insulation layer and are attached to the refrigerating sheet, the fourth heat insulation layer is attached to the third heat insulation layer, and the refrigerating sheet passes through the fourth heat insulation layer and is attached to the refrigerating protrusions.
[0014] In one embodiment, the heat insulation layer further includes a fifth heat insulation layer, and the fifth heat insulation layer is attached to the top of the heat conduction module.
[0015] In one embodiment, one side of the refrigerating sheet is attached to the heat conduction module, and the other side of the refrigerating sheet is attached to the radiator.
[0016] In one embodiment, the radiator includes a heat dissipation copper tube, and the cooling structure further includes a pressing plate. One side of the heat dissipation end of the heat dissipation copper tube is attached to the refrigerating sheet, the pressing plate is disposed on the other side of the heat conduction end of the heat dissipation copper tube, and the pressing plate is used to provide a pressing force to make the heat conduction end of the heat dissipation copper tube in close contact with the refrigerating sheet.
[0017] In one embodiment, the heat conduction module further has a detection groove, and a temperature sensor is disposed in the detection groove.
[0018] In one embodiment, the centrifuge tube cooling structure further includes an outer housing, and the heat conduction module and the heat insulation layer are disposed inside the outer housing.
[0019] In a second aspect, the present application further provides an exhaled gas condensate collection device, which is characterized in that it includes the centrifuge tube cooling structure according to any one of the above; and further includes a centrifuge tube disposed in the heat conduction module and an exhalation nozzle connected to the centrifuge tube.
[0020] The beneficial effects of the present utility model are:
[0021] The above-mentioned centrifuge tube cooling structure is a temperature control structure with dual control of heating and cooling that can provide both heating and cooling functions for the heat conduction module by providing a placement groove for fitting and placing the centrifuge tube, and respectively attaching a heating sheet and a refrigerating sheet on both sides of the heat conduction module. It can accurately and quickly control the temperature at a specific temperature, such as -10°C, -20°C, etc.
[0022] Moreover, a hollowed-out area is provided at the bottom of the heat conduction module, and the placement groove is provided with a through hole communicating with the hollowed-out area. First, it can prevent the gas between the centrifuge tube and the placement groove from blocking the centrifuge tube from being placed in the placement groove when the centrifuge tube is placed in the placement groove, realizing the easy handling of the centrifuge tube. At the same time, since the cooling structure generally needs to lower the temperature to -10 to -20 degrees Celsius below zero, moisture in the air is likely to condense in the placement groove and even freeze at supercooled temperatures, resulting in the centrifuge tube not being able to fit snugly in the placement groove and affecting the refrigeration effect of the heat conduction module on the centrifuge tube. By setting the hollowed-out area, the air extrusion resistance during the placement process of the centrifuge tube can be reduced. Secondly, the hollowed-out area can receive the condensed water generated during the sampling process in the placement groove, and the hollowed-out area forms a sealed air isolation layer during the sampling process, which can also play a heat preservation effect on the heat conduction module. By connecting the hollowed-out area and the placement groove through the through hole, the air in the placement groove can be squeezed into the hollowed-out area during the placement process of the centrifuge tube, and at the same time, the condensed water generated in the placement groove during the sampling process can be guided to the hollowed-out area.
[0023] At the same time, the heating function of the heating sheet (such as setting a temperature higher than room temperature) can be used to evaporate the condensed water in the placement groove and the hollowed-out area after sampling, realizing the maintenance of the structure.
[0024] It should be noted that the heat conduction module refers to a structure with good heat conduction effect, which can enable the structure and the substances inside the structure to achieve rapid heat dissipation or heating, and has high temperature regulation efficiency; the heat preservation layer is a sealed structure arranged on the outer periphery of the heat conduction module, which is used to provide heat preservation for the heat conduction module.
[0025] Other features and advantages of the present utility model will be described in the subsequent specification, and part of them will become obvious from the specification, or will be understood by implementing the present invention. The objectives and other advantages of the present invention can be achieved and obtained through the structures specifically pointed out in the written specification, claims, and drawings. Description of the Drawings
[0026] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the following will briefly introduce the drawings required for the description of the embodiments. Obviously, the drawings described below are only some embodiments recorded in the present application. For those of ordinary skill in the art, other drawings can also be obtained based on these drawings.
[0027] Figure 1 Cross-sectional structure schematic diagram of the centrifuge tube cooling structure in Embodiment 1 of the present invention;
[0028] Figure 2 Schematic diagram of part A structure in the centrifuge tube cooling structure in Embodiment 1 of the present invention;
[0029] Figure 3 Schematic diagram of part B structure in the centrifuge tube cooling structure in Embodiment 1 of the present invention;
[0030] Figure 4 Schematic diagram of the heat conduction structure in the centrifuge tube cooling structure in Embodiment 1 of the present invention;
[0031] Figure 5 Overall structure schematic diagram of the centrifuge tube cooling structure in Embodiment 1 of the present invention;
[0032] Figure 6 Overall structure schematic diagram of the centrifuge tube cooling structure in Embodiment 1 of the present invention;
[0033] Figure 7 Schematic diagram of the temperature sensor of the centrifuge tube cooling structure in Embodiment 1 of the present invention.
[0034] Reference numerals:
[0035] 1. Outer shell; 2. Heat conduction module; 3. Placing groove; 4. Heating sheet; 41. Heating groove; 5. Refrigeration sheet; 51. Refrigeration protrusion; 6. Hollow area; 7. Heat dissipation copper tube; 8. Pressing plate; 9. Through hole; 10. Temperature sensor; 11. Heat dissipation fan; 12. Heat dissipation fin; 13. Heat dissipation air duct; 60. Graphite sheet; 61. First heat insulation layer; 62. U-shaped heat insulation layer; 63. Second heat insulation layer; 64. Hollow layer; 65. Third heat insulation layer; 66. Fourth heat insulation layer; 67. Fifth heat insulation layer; 68. Sixth heat insulation layer. Detailed implementation manners
[0036] The optional embodiments of the present utility model will be described in more detail with reference to the accompanying drawings. Although the optional embodiments of the present utility model are shown in the drawings, it should be understood that the present utility model can be implemented in various forms and should not be limited by the embodiments described herein. On the contrary, these embodiments are provided to make the present utility model more thorough and complete, and to be able to fully convey the scope of the present utility model to those skilled in the art.
[0037] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the technical field to which this utility model belongs. The terms used in the specification of this utility model herein are for the purpose of describing specific embodiments only and are not intended to limit the utility model. The singular forms "a", "the", and "said" used in this utility model and the appended claims are also intended to include the plural forms unless the context clearly dictates otherwise. It should also be understood that the term "and / or" used herein refers to and encompasses any and all possible combinations of one or more of the associated listed items.
[0038] It should be understood that although the terms "first", "second", "third", etc. may be used in this utility model to describe various information, such information should not be limited to these terms. These terms are only used to distinguish the same type of information from each other.
[0039] The methods and devices adopted in this utility model, unless otherwise specified, are conventional reagents, methods, and devices in this technical field.
[0040] For the convenience of understanding the embodiments of this utility model, the centrifugal tube cooling structure in the related art will be described first. The exhaled gas condensate collection device is used to condense the collected human exhaled gas and then analyze it by centrifugation. The traditional exhaled gas condensate collection device is connected to a centrifugal tube, and a local condensation environment is actively formed at the centrifugal tube. However, the cooling structure of the traditional collection device has poor refrigeration effect. Generally, a single refrigeration device is used for one-way refrigeration temperature control. When the temperature drops below the preset temperature, it can only absorb heat from the environment naturally to raise the temperature. When the temperature rises above the preset temperature, the refrigeration is started. This principle results in large temperature fluctuations and insufficient temperature control accuracy, which in turn leads to poor sampling repeatability. Moreover, frequently starting the refrigeration device affects its lifespan. Based on this, this application provides a centrifugal tube cooling structure.
[0041] As shown in the accompanying drawings, a centrifugal tube cooling structure provided in Embodiment 1 of this application includes a heat conduction module 2;
[0042] A placement groove 3 for fitting and placing a centrifugal tube is provided at the top of the heat conduction module 2. A heating sheet 4 is attached to one side of the heat conduction module 2, and a refrigeration sheet 5 is attached to the other side of the heat conduction module 2;
[0043] A heat insulation layer is provided on the outer periphery of the heat conduction module 2. A hollow area 6 is provided between the heat conduction module 2 and the bottom heat insulation layer. The placement groove 3 is provided with a through hole 9 communicating with the hollow area 6.
[0044] By providing a placement groove 3 for fitting and placing a centrifuge tube, and respectively attaching a heating sheet 4 and a cooling sheet 5 on both sides of the heat conduction module 2, a temperature control structure with dual control of heating and cooling that can provide both heating and cooling functions for the heat conduction module 2 can accurately and quickly control the temperature at a specific temperature, such as -10°C, -20°C, etc.;
[0045] Moreover, a hollowed-out area 6 is provided at the bottom of the heat conduction module 2, and the placement groove 3 is provided with a through hole 9 communicating with the hollowed-out area 6; Firstly, it can prevent the gas between the centrifuge tube and the placement groove 3 from blocking the centrifuge tube from being placed in the placement groove 3 when the centrifuge tube is placed in the placement groove 3, realizing the easy handling of the centrifuge tube; At the same time, since the cooling structure generally needs to lower the temperature to -10 to -20 degrees Celsius below zero, the moisture in the air is likely to condense in the placement groove 3 and even freeze at supercooled temperatures, resulting in the centrifuge tube not being able to fit snugly in the placement groove 3 and affecting the cooling effect of the heat conduction module 2 on the centrifuge tube; By providing the hollowed-out area 6, the air extrusion resistance during the placement of the centrifuge tube can be reduced. Secondly, the hollowed-out area 6 can receive the condensed water generated in the placement groove 3 during the sampling process, and the hollowed-out area 6 forms a sealed air layer during the sampling process, which can also play a heat preservation effect on the heat conduction module 2; By connecting the hollowed-out area 6 and the placement groove 3 through the through hole 9, the air in the placement groove 3 can be extruded into the hollowed-out area 6 during the placement of the centrifuge tube, and at the same time, the condensed water generated in the placement groove 3 during the sampling process can be guided to the hollowed-out area 6;
[0046] At the same time, the heating function of the heating sheet 4 (such as setting a temperature higher than room temperature) can be used to evaporate the condensed water in the placement groove 3 and the hollowed-out area 6 after sampling, realizing the maintenance of the structure;
[0047] It should be noted that the heat conduction module 2 refers to a structure with good heat conduction effect, which can enable the structure and the substances inside the structure to achieve rapid heat dissipation or heating, and has a high temperature regulation efficiency; The heat preservation layer is a sealed structure provided on the outer periphery of the heat conduction module 2 for providing heat preservation for the heat conduction module 2.
[0048] In practical applications, the centrifuge tubes that need to be cooled are placed in the placement groove 3. The heat conduction module 2 is quickly cooled by the Peltier element 5. When the temperature drops below the preset temperature, the heating sheet 4 can be activated to heat the heat conduction module 2, so that the heat conduction module 2 can be accurately and stably controlled within the preset temperature range without using the method of naturally absorbing heat from the environment to increase the temperature. As a result, the centrifuge tubes in contact with the heat conduction module 2 can reach the preset temperature range more accurately. At the same time, through the two-way temperature control of cooling and heating, the temperature can be stably controlled. Even if the temperature changes, it fluctuates within a very small range. For example, when it is necessary to cool the heat conduction module 2 to -20 °C, through the two-way temperature control of the Peltier element 5 and the heating sheet 4, the temperature of the heat conduction module 2 can fluctuate within the range of -19.8 to -20.2 °C, achieving a comprehensive condensation effect with high temperature control accuracy and a small temperature fluctuation range.
[0049] In an optional manner in the embodiment of the present invention, the side wall of the placement groove 3 is inclined. The inclination angle of the side wall of the placement groove 3 relative to the vertical plane is 0-3°, which can be adjusted according to the structure of the centrifuge tube. The inclined side wall of the placement groove 3 can better fit the 50 mL centrifuge tubes on the market, improving the condensation effect.
[0050] In an optional manner in the embodiment of the present invention, a heating groove 41 is provided on one side of the heat conduction module 2, and a refrigeration protrusion 51 is provided on the other side opposite to the side where the heating groove 41 is located. The heating sheet 4 is arranged in the heating groove 41, and the Peltier element 5 is in contact with the refrigeration protrusion 51.
[0051] Optionally, the outer side surface of the heating sheet 4 arranged in the heating groove 41 is flush with the outer side of the heat conduction module 2. The heating sheet 4 is just embedded in the heating groove 41, achieving a larger contact area with the heat conduction module 2 and improving the heat conduction efficiency. Optionally, the contact surface of the Peltier element 5 and the refrigeration protrusion 51 matches the surface of the refrigeration protrusion 51, achieving a larger contact area with the heat conduction module 2 and improving the refrigeration efficiency. It should be noted that the descriptions of the heat conduction efficiency and the refrigeration efficiency are for more precisely explaining the effects of the present application. In fact, both the heat conduction efficiency and the refrigeration efficiency refer to the high-efficiency temperature conduction efficiency.
[0052] In an optional manner in the embodiment of the present invention, the heat insulation layer includes a first heat insulation layer 61 and a U-shaped heat insulation layer 62. The first heat insulation layer 61 is arranged outside the heating sheet 4, the heat conduction module 2 is arranged inside the U-shaped heat insulation layer 62, the two sides of the U-shaped heat insulation layer 62 are in contact with the two side surfaces of the heat conduction module 2, and the hollow area 6 is arranged between the heat conduction module 2 and the U-shaped heat insulation layer 62;
[0053] It should be noted that the first thermal insulation layer 61 and the U-shaped thermal insulation layer 62 can be made of thermal insulation cotton or other materials with thermal insulation effects;
[0054] The first thermal insulation layer 61 can improve the thermal insulation effect on one side of the heat conduction module 2 where the heating sheet 4 is located. The U-shaped thermal insulation layer 62 can improve the thermal insulation effects on both sides and the bottom of the heat conduction module 2. At the same time, by setting the hollow area 6, when the centrifuge tube is placed in the placement groove 3, it can prevent the gas between the centrifuge tube and the placement groove 3 from blocking the centrifuge tube from being placed into the placement groove 3, realizing the easy handling of the centrifuge tube; it can reduce the air extrusion resistance during the placement of the centrifuge tube. Secondly, the hollow area 6 can receive the condensed water generated during the sampling process in the placement groove 3, and the hollow area 6 forms a sealed air isolation layer during the sampling process, which can also play a thermal insulation effect on the heat conduction module 2; by connecting the hollow area 6 and the placement groove 3 through the through hole 9, the air in the placement groove 3 can be squeezed into the hollow area 6 during the placement of the centrifuge tube, and at the same time, the condensed water generated in the placement groove 3 during the sampling process can be guided to the hollow area 6;
[0055] At the same time, by means of the heating function of the heating sheet 4 (such as setting a temperature higher than room temperature), the condensed water in the placement groove 3 and the hollow area 6 after sampling can be evaporated to realize the maintenance of the structure;
[0056] In an optional manner in the embodiment of the present utility model, the thermal insulation layer further includes a second thermal insulation layer 63, the second thermal insulation layer 63 is arranged between the first thermal insulation layer 61 and the heating sheet 4, and a hollow layer 64 is further arranged between the second thermal insulation layer 63 and the first thermal insulation layer 61;
[0057] It should be noted that the hollow layer 64 can be an air layer, and the second thermal insulation layer 63 can be a synthetic stone slab or other materials with thermal insulation effects;
[0058] By setting the second thermal insulation layer 63 and the hollow layer 64, the thermal insulation effect on one side of the heat conduction module 2 where the heating sheet 4 is located can be further improved, and the heat provided by the heating sheet 4 can be prevented from dissipating from the outside, affecting the heating effect of the heating sheet 4 on the heat conduction module 2.
[0059] In an optional manner in the embodiment of the present utility model, a graphite sheet 60 is further arranged between the second thermal insulation layer 63 and the heating sheet 4, and the side surface of the graphite sheet 60 is attached to the side surfaces of the heating sheet 4 and the heat conduction module 2;
[0060] It should be noted that the graphite sheet 60 has good heat conduction effect. By arranging the graphite sheet 60 between the heating sheet 4 and the second heat insulation layer 63, the side of the heating sheet 4 that is not in contact with the heat conduction module 2 is connected to the side of the graphite sheet 60, and the side of the graphite sheet 60 in contact with the heating sheet 4 is simultaneously attached to the side of the heat conduction module 2. That is, the area of the graphite sheet 60 is larger than the area of the heating sheet 4. Through the heat conduction effect of the graphite sheet 60, the heat generated on the side of the heating sheet 4 that is not in contact with the heat conduction module 2 is introduced to the side of the heat conduction module 2 through the graphite sheet 60, achieving the improvement of the heating efficiency of the heating sheet 4 and also improving the utilization rate of heat.
[0061] In an optional manner in the embodiment of the present utility model, the heat insulation layer includes a third heat insulation layer 65 and a fourth heat insulation layer 66. The third heat insulation layer 65 and the fourth heat insulation layer 66 are sequentially arranged outside the side of the heat conduction module 2 where the refrigeration protrusion 51 is located. The third heat insulation layer 65 is attached to the side of the heat conduction module 2. The refrigeration protrusion 51 passes through the third heat insulation layer 65 and is attached to the refrigeration sheet 5. The fourth heat insulation layer 66 is attached to the third heat insulation layer 65. The refrigeration sheet 5 passes through the fourth heat insulation layer 66 and is attached to the refrigeration protrusion 51.
[0062] It should be noted that the fourth heat insulation layer 66 can be an insulating board or other materials with good heat insulation effect. The third heat insulation layer 65 can be a foamed silica gel board or other materials with good heat insulation effect. The refrigeration protrusion 51 passes through the third heat insulation layer 65 and is attached to the refrigeration sheet 5, so that the part of the side of the heat conduction module 2 except the refrigeration protrusion 51 can be well covered by the third heat insulation layer 65. While the refrigeration protrusion 51 dissipates heat to the refrigeration sheet 5, the third heat insulation layer 65 can achieve a good heat insulation effect on the part of the side of the heat conduction module 2 except the refrigeration protrusion 51. Similarly, by arranging the fourth heat insulation layer 66, while the refrigeration sheet 5 cools the refrigeration protrusion 51, the fourth heat insulation layer 66 can achieve a good heat insulation effect on the part of the side of the heat conduction module 2 except the refrigeration protrusion 51. By arranging the third heat insulation layer 65 and the fourth heat insulation layer 66, the heat conduction efficiency between the side of the heat conduction module 2 provided with the refrigeration protrusion 51 and the outside is better reduced, and at the same time, it does not affect the refrigeration effect of the refrigeration sheet 5 on the refrigeration protrusion 51 and the heat conduction module 2.
[0063] Optionally, the thickness of the refrigeration protrusion 51 is the same as the thickness of the third heat insulation layer 65, so that the refrigeration protrusion 51 just passes through the third heat insulation layer 65 and is attached to the refrigeration sheet 5. The third heat insulation layer 65 covers all parts of the side of the heat conduction module 2 except the joint surface between the refrigeration protrusion 51 and the refrigeration sheet 5, making the heat insulation effect of the third heat insulation on the side of the heat conduction module 2 and the part outside the joint surface between the refrigeration protrusion 51 and the refrigeration sheet 5 better.
[0064] In an alternative embodiment of the present utility model, the thermal insulation layer further includes a fifth thermal insulation layer 67, which is attached to the top of the heat conduction module 2; it should be noted that the fifth thermal insulation layer 67 can be a bakelite board or other materials with good thermal insulation effects; the fifth thermal insulation layer 67 is provided with an opening, and the opening is matched with the opening of the placement groove 3, so that the centrifuge tube can enter the placement groove 3; by providing the fifth thermal insulation layer 67, the thermal insulation effect of the top of the heat conduction module 2 can be improved.
[0065] In an alternative embodiment of the present utility model, the thermal insulation layer further includes a sixth thermal insulation layer 68, which is attached to the outside of the first thermal insulation layer 61; it should be noted that the sixth thermal insulation layer 68 can be a bakelite board or other materials with good thermal insulation effects; by providing the sixth thermal insulation layer 68, the thermal insulation effect of the side of the heat conduction module 2 can be improved.
[0066] In an alternative embodiment of the present utility model, one side of the refrigeration chip 5 is attached to the heat conduction module 2, and the other side of the refrigeration chip 5 is attached to the radiator; by providing the radiator, it has a good heat dissipation effect on the refrigeration chip 5 and improves the refrigeration effect of the refrigeration chip 5;
[0067] It should be noted that the refrigeration chip can be a semiconductor refrigeration chip, and its principle is as follows. When an electric current passes through a loop formed by connecting two different semiconductor materials (usually N-type semiconductor and P-type semiconductor), heat absorption or heat release will occur at the joint because the diffusion and migration of electrons and holes are different on the contact surface of the two semiconductors; in the N-type semiconductor, the main carriers are electrons and the electron concentration is high; in the P-type semiconductor, the main carriers are holes and the hole concentration is high. When they are connected to form a loop and an electric current passes through, electrons will move from the N-type semiconductor to the P-type semiconductor, and holes will move from the P-type semiconductor to the N-type semiconductor; in this process, the migration of electrons and holes will take away or bring energy. Driven by the electric current, when electrons move from the low-energy state end to the high-energy state end, heat needs to be absorbed, and this joint will show heat absorption, achieving the refrigeration effect; while when electrons move from the high-energy state to the low-energy state, heat will be released, and this joint will show heat release. The semiconductor refrigeration chip precisely uses this heat absorption and heat release characteristic to achieve heat absorption and refrigeration at one end and heat release and heat dissipation at the other end; in the embodiment of the present invention, the heat absorption and refrigeration end is connected to the refrigeration protrusion 51, and the heat release and heat dissipation end can be connected to the radiator.
[0068] In an alternative embodiment of the present utility model, the radiator includes a heat dissipation copper tube 7, and the cooling structure further includes a pressing plate 8. One side of the heat dissipation end of the heat dissipation copper tube 7 is attached to the refrigeration chip 5, and the pressing plate 8 is arranged on the other side of the heat conduction end of the heat dissipation copper tube 7. The pressing plate 8 is used to provide a pressing force to make the heat conduction end of the heat dissipation copper tube 7 in close contact with the refrigeration chip 5;
[0069] Optionally, the pressing plate 8 can be fixedly connected to the fourth heat insulation layer 66 or the heat conduction module 2 by bolts. Through the pressing action of the pressing plate 8 on the refrigeration chip 5 and the heat conduction module 2, the heat conduction end of the heat dissipation copper tube 7 can be more closely contacted with the refrigeration chip 5, thereby improving the refrigeration effect.
[0070] In an optional manner in the embodiment of the present utility model, the radiator further includes a cooling fan 11 and a cooling air duct 13. The heat dissipation copper tube 7 is fixedly connected to the heat dissipation fins 12. The cooling fan 11 is arranged on both sides of the heat dissipation fins 12, and the cooling air duct 13 is connected to the outside of the cooling fan 11. Through the heat dissipation fins 12, the cooling fan 11 and the cooling air duct 13, the heat dissipation efficiency of the heat dissipation copper tube 7 is improved, thereby improving the refrigeration effect of the refrigeration chip 5 on the heat conduction module 2. By setting the cooling air duct 13, the airflow with heat can be directly guided to the outside of the structure, avoiding the influence of the return of the gas with heat on the heat dissipation effect.
[0071] In an optional manner in the embodiment of the present utility model, the heat conduction module 2 is further provided with a detection groove, and a temperature sensor 10 is arranged in the detection groove. By setting the detection groove, the temperature sensor 10 is arranged inside the heat conduction module 2, improving the accuracy and timeliness of temperature detection, being able to accurately and timely reflect the temperature of the heat conduction module 2, and making the temperature control of the heat conduction module 2 more accurate and efficient.
[0072] In an optional manner in the embodiment of the present utility model, the centrifuge tube cooling structure further includes an outer shell 1, and the heat conduction module 1 and the heat insulation layer are arranged inside the outer shell 1.
[0073] An exhaled gas condensate collection device provided in Embodiment 2 of the present application includes the centrifuge tube cooling structure described in any one of the above; it further includes a centrifuge tube arranged in the heat conduction module 2 and an exhalation nozzle connected to the centrifuge tube.
[0074] By setting an exhaled gas condensate collection device with a centrifuge tube cooling structure, the temperature can be accurately and quickly controlled at a specific temperature, such as -10°C, -20°C, etc.; at the same time, a heating sheet 4 and a hollowed-out area 6 are provided, and the heating function of the heating sheet 4 (such as setting a temperature higher than room temperature) can be used to evaporate the condensed water in the sampling placement groove 3 and the hollowed-out area 6 after sampling, realizing the maintenance of the structure; thereby achieving a better exhaled gas condensation and collection effect.
[0075] In an optional embodiment, label 1, the present application embodiment further provides a centrifuge tube cooling structure, an outer shell and a heat conduction module arranged inside the outer shell;
[0076] The top of the heat conduction module is provided with a placement groove for fitting and placing a centrifuge tube. A heating sheet is attached to one side of the heat conduction module, and a cooling sheet is attached to the other side of the heat conduction module.
[0077] A heat insulation layer is provided on the outer periphery of the heat conduction module. There is a hollow area between the heat conduction module and the bottom heat insulation layer. The placement groove is provided with a through hole communicating with the hollow area.
[0078] Among them, for reference numeral 2, on the basis of reference numeral 1, a heating groove is provided on one side of the heat conduction module, and a cooling protrusion is provided on the other side opposite to the side where the heating groove is located. The heating sheet is arranged in the heating groove, and the cooling sheet is attached to the cooling protrusion.
[0079] Among them, for reference numeral 3, on the basis of reference numeral 1, the heat insulation layer includes a first heat insulation layer and a U-shaped heat insulation layer. The first heat insulation layer is arranged outside the heating sheet, the heat conduction module is arranged inside the U-shaped heat insulation layer, the two sides of the U-shaped heat insulation layer are attached to the two side surfaces of the heat conduction module, and the hollow area is arranged between the heat conduction module and the U-shaped heat insulation layer.
[0080] Among them, for reference numeral 4, on the basis of reference numeral 3, the heat insulation layer further includes a second heat insulation layer. The second heat insulation layer is arranged between the first heat insulation layer and the heating sheet, and there is also a hollow layer between the second heat insulation layer and the first heat insulation layer.
[0081] Among them, for reference numeral 5, on the basis of reference numeral 4, a graphite sheet is further arranged between the second heat insulation layer and the heating sheet. The side surface of the graphite sheet is attached to the side surfaces of the heating sheet and the heat conduction module.
[0082] Among them, for reference numeral 6, on the basis of reference numeral 2, the heat insulation layer includes a third heat insulation layer and a fourth heat insulation layer. The third heat insulation layer and the fourth heat insulation layer are sequentially arranged outside the side surface of the heat conduction module where the cooling protrusion is located; the third heat insulation layer is attached to the side surface of the heat conduction module, the cooling protrusion passes through the third heat insulation layer and is attached to the cooling sheet, the fourth heat insulation layer is attached to the third heat insulation layer, and the cooling sheet passes through the fourth heat insulation layer and is attached to the cooling protrusion.
[0083] Among them, for reference numeral 7, on the basis of reference numeral 6, one side of the cooling sheet is attached to the heat conduction module, and the other side of the cooling sheet is attached to the radiator.
[0084] Among them, for reference numeral 8, on the basis of reference numeral 7, the radiator includes a heat dissipation copper tube. The cooling structure is further provided with a pressing plate. One side of the heat dissipation end of the heat dissipation copper tube is attached to the cooling sheet, the pressing plate is arranged on the other side of the heat conduction end of the heat dissipation copper tube, and the pressing plate is used to provide a pressing force to make the heat conduction end of the heat dissipation copper tube in close contact with the cooling sheet.
[0085] Among them, label 9, based on label 1, the heat conduction module is further provided with a detection groove, and a temperature sensor is arranged in the detection groove.
[0086] In an alternative embodiment, label 10, an exhaled gas condensate collection device includes the centrifuge tube cooling structure according to any one of labels 1-9; it further includes a centrifuge tube arranged in the heat conduction module and an exhalation nozzle connected to the centrifuge tube.
[0087] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements on some of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the spirit and scope of the technical solutions of the various embodiments of the present invention.
Claims
1. A centrifuge tube cooling structure, characterized in that: Including thermal conductivity module; The top of the heat conduction module is provided with a placement groove for fitting and placing the centrifuge tube, the heating plate is fitted and arranged on one side of the heat conduction module, and the cooling plate is fitted and arranged on the other side of the heat conduction module; A heat-insulating layer is arranged on the periphery of the heat-conducting module, a hollow area is arranged between the heat-conducting module and the bottom heat-insulating layer, and a through hole is arranged on the placement groove to communicate with the hollow area.
2. The centrifuge tube cooling structure according to claim 1, characterized in that: A heating groove is arranged on one side of the heat conduction module, and a cooling protrusion is arranged on the other side opposite to the heating groove. The heating plate is arranged in the heating groove, and the cooling plate is fitted with the cooling protrusion.
3. The centrifuge tube cooling structure according to claim 1, characterized in that: The thermal insulation layer includes a first thermal insulation layer and a U-shaped thermal insulation layer, the first thermal insulation layer is arranged on the outside of the heating plate, the thermal conductive module is arranged on the inside of the U-shaped thermal insulation layer, the two sides of the U-shaped thermal insulation layer are bonded to the two side surfaces of the thermal conductive module, and the hollow area is arranged between the thermal conductive module and the U-shaped thermal insulation layer.
4. The centrifuge tube cooling structure according to claim 3, characterized in that: The heat-insulating layer further comprises a second heat-insulating layer, wherein the second heat-insulating layer is arranged between the first heat-insulating layer and the heating plate, and a hollow layer is further arranged between the second heat-insulating layer and the first heat-insulating layer.
5. The centrifuge tube cooling structure according to claim 4, characterized in that: A graphite sheet is further provided between the second heat-insulating layer and the heating sheet, and a side surface of the graphite sheet is in contact with the heating sheet and a side surface of the heat-conducting module.
6. The centrifuge tube cooling structure according to claim 2, characterized in that: The thermal insulation layer includes a third thermal insulation layer and a fourth thermal insulation layer, and the third thermal insulation layer and the fourth thermal insulation layer are sequentially arranged on the outside of the side of the heat conductive module where the refrigeration protrusion is located; the third thermal insulation layer is bonded to the side of the heat conductive module, the refrigeration protrusion passes through the third thermal insulation layer and is bonded to the refrigeration plate, the fourth thermal insulation layer is bonded to the third thermal insulation layer, and the refrigeration plate passes through the fourth thermal insulation layer and is bonded to the refrigeration protrusion.
7. The centrifuge tube cooling structure according to claim 6, characterized in that: One side of the cooling plate is in contact with the heat conduction module, and the other side of the cooling plate is in contact with the heat sink.
8. The centrifuge tube cooling structure according to claim 7, characterized in that: The radiator includes a heat dissipation copper tube, and the cooling structure is also provided with a clamping plate. One side of the heat dissipation end of the heat dissipation copper tube is in contact with the refrigeration fin, and the clamping plate is arranged on the other side of the heat conduction end of the heat dissipation copper tube. The clamping plate is used to provide a pressing force to make the heat conduction end of the heat dissipation copper tube in close contact with the refrigeration fin.
9. The centrifuge tube cooling structure according to claim 1, characterized in that: The heat conduction module is also provided with a detection groove, and a temperature sensor is arranged in the detection groove.
10. An exhaled gas condensate collection device, characterized in that: The invention comprises the centrifuge tube cooling structure according to any one of claims 1 to 9; and further comprises a centrifuge tube arranged in the heat conduction module and an exhalation mouthpiece connected to the centrifuge tube.