Poly-L-lactic acid microsphere preparation device

By designing a levo polylactic acid microsphere preparation device including a two-direction rotating stirring device and a scraper, the problem of insufficient stirring caused by the viscosity of the raw materials is solved, and a more efficient emulsification effect and scraping of the inner wall of the stirring tank is achieved.

CN222958950UActive Publication Date: 2025-06-10XINWO MEDICAL BEAUTY (GUANGDONG) BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202421727926.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-07-19
Publication Date
2025-06-10
Estimated Expiration
2034-07-19

AI Technical Summary

Technical Problem

During the stirring process, the existing L-polylactic acid microsphere manufacturing equipment is easy to adhere to the inner wall of the stirring tank due to the viscosity of the raw materials, making it difficult to be fully stirred, affecting the emulsification effect.

Method used

A polyL-lactic acid microsphere preparation device is designed, including a rotating stirring tank, first and second stirring devices, as well as a driving motor and a transmission device. Through the design of the stirring shaft and scraper rotating in both directions, strong shear and impact forces can be generated to ensure that the material is fully stirred, and contact with the inner wall of the stirring tank through the scraper to scrape off the adherent material.

Benefits of technology

It effectively solves the problem of material adhesion, improves the emulsification effect of raw materials, and ensures sufficient scraping of materials on the inner wall of the mixing tank.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of poly (L-lactic acid) microsphere manufacturing equipment, in particular to a poly (L-lactic acid) microsphere preparation device which comprises a rotating disc, a stirring tank, a second stirring shaft, a second stirring rod and a scraping plate, the rotating disc rotates to drive the stirring tank to rotate, and the second stirring shaft is rotatably connected into the stirring tank; the second stirring rod is connected to the outer wall of the second stirring shaft, and the scraping plate is connected with the second stirring shaft through the second stirring rod, so that the scraping plate is in contact with the inner wall of the stirring tank when the second stirring shaft is in a certain rotating state, and materials on the inner wall of the stirring tank can be scraped by utilizing the rotation of the stirring tank, so that the stirring effect of raw materials is improved; and the overall emulsification effect is improved.
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Description

Technical Field

[0001] The utility model relates to the technical field of equipment for manufacturing left-handed polylactic acid microspheres, and particularly relates to a device for preparing poly-L-lactic acid microspheres. Background Technique

[0002] A Chinese patent with the authorization announcement number CN219667107U discloses a device for manufacturing left-handed polylactic acid microspheres. Specifically disclosed is including a base, a stirring tank is arranged at the center position of the top of the base, a top cover is arranged on the top of the stirring tank in a liftable manner, an inner tank is clamped inside the stirring tank, a stirring mechanism is installed on the top cover, the stirring mechanism includes a stirring motor and a stirring rod, an air outlet pipe is arranged on the top cover on one side of the stirring motor, a heating mechanism is arranged at the bottom of the stirring tank, the heating mechanism includes a heating table and a heating resistance wire, the heating table is located at the inner bottom of the stirring tank, and the heating resistance wire is installed on the heating table. This patent can well vaporize and discharge the moisture and volatile substances in the PLA raw materials.

[0003] However, there are still some deficiencies in this patent; due to the viscosity of the raw materials themselves, the raw materials are prone to adhering to the inner wall of the casing of the stirring tank and are difficult to be fully stirred, affecting the overall emulsification effect. Therefore, there is an urgent need for a device for preparing poly-L-lactic acid microspheres that can scrape the materials on the inner wall of the casing of the stirring tank, thereby improving the emulsification effect of the raw materials. Summary of the Utility Model

[0004] The technical problem to be solved by the utility model is: to provide a device for preparing poly-L-lactic acid microspheres that can scrape the materials on the inner wall of the casing of the stirring tank, thereby improving the emulsification effect of the raw materials.

[0005] To solve the above technical problem, the technical solution adopted by the utility model is: a device for preparing poly-L-lactic acid microspheres, including:

[0006] A base, on which a turntable is provided, and a circular groove matching the stirring tank is provided on the turntable;

[0007] A stirring tank, which is rotatably connected in the circular groove;

[0008] A first stirring device, the first stirring device includes a first stirring shaft and a first stirring rod, the first stirring shaft is coaxially and rotatably connected inside the stirring tank, and a plurality of first stirring rods are circumferentially arranged on the outer wall of the first stirring shaft in a circumferential array with the stirring tank as the axis, and the rotation direction of the first stirring shaft is opposite to the rotation direction of the stirring tank;

[0009] The second stirring device, which includes a second stirring shaft, second stirring rods, and a scraper. The root of the second stirring shaft is rotatably connected inside the stirring tank. A number of second stirring shafts are circumferentially arrayed around the axis of the stirring tank. A number of second stirring rods are circumferentially arrayed on the outer wall of the second stirring shaft along the axis of the second stirring shaft. The scraper is in the shape of a strip and is connected to the second stirring shaft through the second stirring rods. In a certain state of rotation of the second stirring shaft, the scraper contacts the inner wall of the stirring tank;

[0010] The driving motor, which is connected to the base and is in transmission connection with the turntable;

[0011] The transmission device, which includes a connecting plate, a first gear, a second gear, and a toothed ring. One end of the connecting plate is connected to the upper part of the first stirring shaft through a first bearing seat, and the other end of the connecting plate is connected to the base. The lower part of the first stirring shaft is connected to the bottom inner wall of the stirring tank through a second bearing seat. The first gear is coaxially connected to the first stirring shaft and is located between the first bearing seat and the second bearing seat. The toothed ring is connected to the inner wall of the stirring tank. The upper end of the second stirring shaft is rotatably connected to the lower part of the connecting plate, and the lower end of the second stirring shaft is connected to the bottom of the stirring tank through a third bearing seat. The second gear is coaxially connected to the second stirring shaft and is located between the toothed ring and the first gear. The second gear meshes with the toothed ring, and the second gear meshes with the first gear.

[0012] Furthermore, the connecting plate is in the shape of a cross, and the second stirring shaft is connected below the end of the cross shape of the connecting plate.

[0013] Furthermore, the base is in the shape of a rectangle, and connecting columns are provided around the lower part of the base. Rotatable wheels are provided at the lower ends of the connecting columns.

[0014] Furthermore, a discharge pipe is provided at the bottom of the outer wall of the stirring tank, and a valve is provided on the discharge pipe.

[0015] Furthermore, the first stirring rods and the second stirring rods are staggered.

[0016] Furthermore, the poly-L-lactic acid microsphere preparation device further includes a circular partition plate, which is connected to the first stirring shaft and the second stirring shaft through a third bearing seat. The circular partition plate is in clearance fit with the inner wall of the stirring tank and is located below the first gear. A feed inlet is provided on the circular partition plate.

[0017] The beneficial effect of the present utility model is that, compared with the prior art, it can scrape the materials on the inner wall of the casing of the stirring tank, thereby improving the emulsification effect of the raw materials. Description of the Drawings

[0018] Figure 1 It is a schematic structural diagram of a poly-L-lactic acid microsphere preparation device according to a specific embodiment of the present utility model;

[0019] Figure 2 The front view of a preparation device for poly-L-lactic acid microspheres according to a specific embodiment of the present invention;

[0020] Figure 3 is Figure 2 the solid diagram of the sectional view taken along the direction A of

[0021] Figure 4 is Figure 2 the sectional view taken along the direction B of

[0022] Label description

[0023] 1. Base; 11. Turntable; 12. Connecting column; 121. Wheel;

[0024] 2. Stirring tank; 21. Discharge pipeline; 211. Valve;

[0025] 3. First stirring device; 31. First stirring shaft; 32. First stirring rod;

[0026] 4. Second stirring device; 41. Second stirring shaft; 42. Second stirring rod;

[0027] 5. Scraper;

[0028] 6. Driving motor;

[0029] 7. Transmission device; 71. Connecting plate; 72. First gear; 73. Second gear; 74. Tooth ring;

[0030] 8. Partition board. Specific embodiment

[0031] To describe in detail the technical content, achieved purpose and effects of the present invention, the following is described in conjunction with the embodiments and with reference to the drawings.

[0032] Please refer to Figures 1 to 4 , a preparation device for poly-L-lactic acid microspheres, comprising:

[0033] Base 1, on which a turntable 11 is provided, and a circular groove matching the stirring tank 2 is provided on the turntable 11;

[0034] Stirring tank 2, which is rotatably connected in the circular groove;

[0035] First stirring device 3, which includes a first stirring shaft 31 and a first stirring rod 32. The first stirring shaft 31 is coaxially and rotatably connected in the stirring tank 2, and a plurality of first stirring rods 32 are circumferentially arranged on the outer wall of the first stirring shaft 31 with the stirring tank 2 as the axis, and the rotation direction of the first stirring shaft 31 is opposite to the rotation direction of the stirring tank 2;

[0036] The second stirring device 4, the second stirring device 4 includes a second stirring shaft 41, second stirring rods 42 and a scraper 5. The root of the rod of the second stirring shaft 41 is rotatably connected inside the stirring tank 2. A plurality of second stirring shafts 41 are circumferentially arrayed around the axis of the stirring tank 2. A plurality of second stirring rods 42 are circumferentially arrayed on the outer wall of the second stirring shaft 41 along the axis of the second stirring shaft 41. The scraper 5 is in a strip shape. The scraper 5 is connected to the second stirring shaft 41 through the second stirring rods 42. In a certain state of rotation of the second stirring shaft 41, the scraper 5 is in contact with the inner wall of the stirring tank 2;

[0037] The driving motor 6, the driving motor 6 is connected to the base 1, and the driving motor 6 is in transmission connection with the turntable 11;

[0038] The transmission device 7, the transmission device 7 includes a connecting plate 71, a first gear 72, a second gear 73 and a gear ring 74. One end of the connecting plate 71 is connected to the upper part of the first stirring shaft 31 through a first bearing seat. The other end of the connecting plate 71 is connected to the base 1. The lower part of the first stirring shaft 31 is connected to the inner wall of the bottom of the stirring tank 2 through a second bearing seat. The first gear 72 is coaxially connected to the first stirring shaft 31. The first gear 72 is located between the first bearing seat and the second bearing seat. The gear ring 74 is connected to the inner wall of the stirring tank 2. The upper end of the second stirring shaft 41 is rotatably connected to the lower part of the connecting plate 71. The lower end of the second stirring shaft 41 is connected to the bottom of the stirring tank 2 through a third bearing seat. The second gear 73 is coaxially connected to the second stirring shaft 41. The second gear 73 is located between the gear ring 74 and the first gear 72. The second gear 73 meshes with the gear ring 74. The second gear 73 meshes with the first gear 72.

[0039] In the above embodiments, raw materials are put into the stirring tank 2, the driving motor 6 is started, the driving motor 6 drives the stirring tank 2 to rotate. The stirring tank 2 rotates clockwise. The second gear 73 meshes with the gear ring 74, so that the second gear 73 rotates self - clockwise, driving the second stirring shaft 41 to rotate. The self - rotation of the second gear 73 drives the first gear 72 to rotate, so that the first stirring shaft 31 rotates counter - clockwise. Using the fact that the rotation direction of the stirring tank 2 is opposite to that of the first stirring shaft 31, stronger shear force and impact force can be generated. These forces help to refine, disperse the material particles and accelerate dissolution. At the same time, the two - way rotation can also reduce the dead corners and blind areas during the stirring process, ensuring that the materials are fully stirred throughout the stirring tank 2. Since the scraper 5 is connected to the second stirring rods 42 of the second stirring shaft 41, when the second stirring shaft 41 rotates, the scraper 5 is in contact with the inner wall of the stirring tank 2. Then, as the stirring tank 2 rotates clockwise, the scraper 5 can scrape the materials on the inner wall of the stirring tank 2 along the clockwise rotation direction, thereby improving the stirring and emulsifying effect. Compared with the prior art, it can scrape the materials on the inner wall of the casing of the stirring tank 2, thus improving the emulsifying effect of the raw materials.

[0040] As an alternative embodiment, the connecting plate 71 is in a cross shape, and the second stirring shaft 41 is connected below the end of the cross shape of the connecting plate 71.

[0041] In the above embodiments, the space inside the stirring tank 2 can be utilized to the maximum extent, thereby improving the emulsification effect inside the stirring tank 2.

[0042] As an alternative embodiment, the base 1 is in a rectangular shape, connecting columns 12 are provided around the lower part of the base 1, and rotatable wheels 121 are provided at the lower ends of the connecting columns 12.

[0043] In the above embodiments, by providing the connecting columns 12 and the wheels 121, the stirring tank 2 can be moved to any place, which is convenient and practical.

[0044] As an alternative embodiment, a discharge pipe 21 is provided at the bottom of the outer wall of the stirring tank 2, and a valve 211 is provided on the discharge pipe 21.

[0045] In the above embodiments, by opening the valve 211, the materials stirred in the stirring tank 2 are discharged through the discharge pipe 21.

[0046] As an alternative embodiment, the first stirring rods and the second stirring rods 42 are distributed alternately.

[0047] In the above embodiments, by the alternate distribution of the first stirring rods 32 and the second stirring rods 42, the shearing force is enhanced and the emulsification effect is improved.

[0048] As an alternative embodiment, the poly-L-lactic acid microsphere preparation device further includes a circular partition plate 8. The circular partition plate 8 is connected to the first stirring shaft 31 and the second stirring shaft through a third bearing seat. The circular partition plate 8 is in clearance fit with the inner wall of the stirring tank 2. The circular partition plate 8 is located below the first gear 72, and a feed inlet is provided on the circular partition plate 8.

[0049] In the above embodiments, by providing the circular partition plate 8 to separate the first gear 72, the ring gear 74 and the second gear 73, and then feeding materials through the feed inlet, the gears are prevented from being contaminated by the raw materials.

[0050] The above are only the embodiments of the present invention, and do not limit the patent scope of the present invention accordingly. Any equivalent transformation made by using the content of the specification and drawings of the present invention, or directly or indirectly applied in the relevant technical fields, shall be equally included in the patent protection scope of the present invention.

Claims

1. A poly (L-lactic acid) microsphere preparation device, characterized in that: include: A base, wherein a turntable is provided on the base, and a circular groove matching the mixing tank is provided on the turntable; A mixing tank, the mixing tank is rotatably connected in the circular tank; a first stirring device, the first stirring device comprising a first stirring shaft and a first stirring rod, the first stirring shaft being coaxially rotatably connected to the stirring tank, a plurality of first stirring rods being distributed on the outer wall of the first stirring shaft in a circular array with the stirring tank as the axial direction, and the rotation direction of the first stirring shaft being opposite to that of the stirring tank; The second stirring device comprises a second stirring shaft, a second stirring rod and a scraper. If the second stirring shaft is rotatably connected to the stirring tank, a plurality of second stirring shafts are arranged in a circular array with the stirring tank as the axis, a plurality of second stirring rods are arranged in a circular array on the outer wall of the second stirring shaft with the axis of the second stirring shaft, and the scraper is in a strip shape. The scraper is connected to the second stirring shaft through the second stirring rod. When the second stirring shaft is in a certain state of rotation, the scraper contacts the inner wall of the stirring tank; A driving motor, the driving motor is connected to the base, and the driving motor is drivingly connected to the turntable; A transmission device, the transmission device includes a connecting plate, a first gear, a second gear and a gear ring, one end of the connecting plate is connected to the upper part of the first stirring shaft through the first bearing seat, the other end of the connecting plate is connected to the base, the lower part of the first stirring shaft is connected to the bottom inner wall of the stirring tank through the second bearing seat, the first gear is coaxially connected to the first stirring shaft, the first gear is located between the first bearing seat and the second bearing seat, the gear ring is connected to the inner wall of the stirring tank, the upper end of the second stirring shaft is rotatably connected to the lower part of the connecting plate, the lower end of the second stirring shaft is connected to the bottom of the stirring tank through the third bearing seat, the second gear is coaxially connected to the second stirring shaft, the second gear is located between the gear ring and the first gear, the second gear is meshed with the gear ring, and the second gear is meshed with the first gear.

2. The poly (L-lactic acid) microsphere preparation device according to claim 1, characterized in that: The connecting plate is in a cross shape, and the second stirring shaft is connected below the end of the cross-shaped connecting plate.

3. The poly (L-lactic acid) microsphere preparation device according to claim 1, characterized in that: The base is in a rectangular shape, and connecting columns are arranged around the lower side of the base, and rotatable wheels are arranged at the lower ends of the connecting columns.

4. The poly (L-lactic acid) microsphere preparation device according to claim 1, characterized in that: A discharge pipe is arranged at the bottom of the outer wall of the mixing tank, and a valve is arranged on the discharge pipe.

5. The poly (L-lactic acid) microsphere preparation device according to claim 1, characterized in that: The first stirring rod and the second stirring rod are arranged alternately.

6. The poly (L-lactic acid) microsphere preparation device according to claim 1, characterized in that: The poly (L-lactic acid) microsphere preparation device also includes a circular partition, which is connected to the first stirring shaft and the second stirring shaft through a third bearing seat, and has a clearance fit with the inner wall of the stirring tank. The circular partition is located below the first gear, and a feed port is provided on the circular partition.

Citation Information

Patent Citations

  • L-polylactic acid microsphere manufacturing equipment

    CN219667107U