Sampling equipment for biological reagent
By designing a sampling device including a mobile module and a batch rotating device, the problems of manual operation instability and reagent leakage in the prior art are solved, efficient and accurate sampling and automated operation of biological reagents are achieved, and the work efficiency of the laboratory is improved.
Patent Information
- Application Number
- CN202421582339.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-05
- Publication Date
- 2025-06-13
- Estimated Expiration
- 2034-07-05
AI Technical Summary
The existing sampling equipment requires manual operation, which poses instability and risk of reagent leakage, affecting the progress of the experimental work.
A sampling device including a base, storage platform, intermittent rotation device, extraction device, test tube medicine holder, control computer and reagent platform is designed. It uses Y-axis, Z-axis, X-axis moving modules and infrared detectors to achieve efficient and accurate biological reagent sampling, and automatically rotates the measuring cup through the intermittent rotation device to reduce manual operation.
It realizes efficient and accurate biological reagent sampling, improves the work efficiency of the laboratory, reduces the need for manual operation, and ensures accurate insertion of the sampling needle through infrared detectors, improving the accuracy of sampling.
Smart Images

Figure CN222979156U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the field of clinical testing instruments, in particular to a sampling device for biological reagents. Background Art
[0002] In the fully automatic biochemical analyzer, the sampling device plays a vital role. The main function of the sampling device is to transfer the liquid sample from the specimen bottle to the reagent bottle. After sufficient reaction, the mixed liquid is transferred to the counter for detection. In this process, the biochemical analyzer usually includes a cantilever mechanism and a driving mechanism, wherein the cantilever mechanism includes key components such as a sampling stirring arm, a stirring paddle and a sampling needle. One end of the sampling stirring arm is connected to the driving mechanism, and the other end is a free end. The motor is fixed to the sampling stirring arm through a motor bracket to drive the sampling operation. At the same time, a certain amount of reagent is delivered in proportion as required by a proportional pump, i.e., a piston infusion pump. At present, some sampling devices still require technicians to transfer the liquid sample to the reagent bottle by hand-held suction tubes. This manual operation method is not only unstable, but may also cause the reagent to leak due to vibration and collision during the transfer, thereby delaying the progress of the experimental work. For this reason, we propose a sampling device for biological reagents. Utility Model Content
[0003] 1. Technical issues to be resolved
[0004] In view of the deficiencies in the prior art, the utility model provides a sampling device for biological reagents, which solves the above-mentioned problems.
[0005] (II) Technical solution
[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a sampling device for biological reagents, comprising a base, a storage platform, an intermittent rotating device, an extraction device, a test tube medicine rack, a control computer and a reagent platform, the storage platform is fixedly installed on the top of the base, the extraction device is arranged on one side of the top of the storage platform, the test tube medicine rack is arranged on the side of the top of the storage platform away from the extraction device, the reagent platform is arranged on the end of the storage platform away from the test tube medicine rack, the interior of the base is hollow, and the intermittent rotating device is arranged on the side of the interior close to the reagent platform, and the control computer is fixedly installed on the side of the base close to the test tube medicine rack.
[0007] Preferably, the extraction device includes a Y-axis movement module, a Z-axis movement module, an X-axis movement module, and an extraction device support. An extraction device support is provided on one side of the top of the placement platform away from the test tube medicine placement rack. The extraction device support is in a gate shape. A Y-axis movement module is provided on the vertical support on the side of the extraction device support close to the reagent platform. The top horizontal support of the extraction device support away from the placement platform and facing the test tube medicine placement rack is provided with a Z-axis movement module. An X-axis movement module is provided on one side of the top of the placement platform away from the control computer.
[0008] Preferably, the Y-axis movement module, the Z-axis movement module, and the X-axis movement module include fixed brackets, belt motors, belt pulleys, belts, support columns, and connecting rod support blocks. There are two groups of fixed brackets. One side of the top of the two groups of fixed brackets extends to form a Y-shaped bracket. Support columns are respectively fixedly installed at both ends of the Y-shaped bracket of the fixed bracket. The two groups of fixed brackets are connected by the two groups of support columns. On one side of the top of one end of the fixed bracket away from the Y-shaped bracket, a belt motor is fixedly installed, and a belt pulley is fixedly installed at the corresponding other end. The belt motor and the belt pulley are driven by a belt. The Y-axis movement module, the Z-axis movement module, and the X-axis movement module are all fixedly installed on the surfaces of the extraction device support and the placement platform through multiple groups of fixed brackets.
[0009] Preferably, the extraction device further includes connecting rod support blocks, first connecting rods, second connecting rods, and an extraction module. Connecting rod support blocks are slidably sleeved on the support columns of the Y-axis movement module, the Z-axis movement module, and the X-axis movement module. The bottom end of the connecting rod support block is fixedly connected to the belt. The top end of the connecting rod support block is hingedly installed with a first connecting rod. The other end of the first connecting rod is hinged to the second connecting rod. The other ends of multiple groups of second connecting rods are all hinged to the extraction module.
[0010] Preferably, the extraction module includes an extraction module base, an infrared detector, and a sampling needle. The extraction module is hinged to multiple groups of second connecting rods through the outer surface of the extraction module base. A sampling needle is fixedly installed at the bottom end of the extraction module base. Multiple groups of infrared detectors are fixedly installed around the bottom end of the extraction module base. The multiple groups of infrared detectors are distributed in a cross shape.
[0011] Preferably, multiple measuring cup fixing racks are fixedly installed on the top of the reagent platform. The bottom end of the reagent platform is connected to the intermittent rotation device.
[0012] Preferably, the intermittent rotation device includes a dial, a round pin, a bow-shaped plate, a rotating column, a grooved wheel, and a rotating motor. One end of the rotating motor away from the output shaft is fixedly installed at the bottom end inside the base. The output shaft of the rotating motor is fixedly connected to the dial. A round pin is fixedly installed on one side of the top end of the dial. A bow-shaped plate is fixedly installed on the side of the dial away from the round pin. A rotating column is fixedly installed at the center of the grooved wheel. The rotating column extends through the top end of the placement platform and is fixedly installed together with the reagent platform. An arc-shaped slot is opened inside the grooved wheel, and a straight slot is opened inside the arc-shaped slot. One end of the bow-shaped plate away from the round pin corresponds to the radian of the arc-shaped slot, and the round pin corresponds to the diameter of the straight slot.
[0013] (III) Beneficial effects
[0014] Compared with the prior art, the present utility model provides a sampling device for biological reagents, which has the following beneficial effects:
[0015] 1. For the sampling device for biological reagents, the extraction device can achieve efficient and accurate sampling of biological reagents through the moving module, improving the working efficiency of the laboratory. The use of the infrared detector ensures that the sampling needle can accurately insert into the test tube, improving the accuracy of sampling.
[0016] 2. For the sampling device for biological reagents, the intermittent rotation device realizes precise intermittent rotation movement through the coordinated work of components such as the dial, round pin, bow-shaped plate, grooved wheel, and rotating motor. This movement mode ensures that the measuring cup on the reagent platform can rotate at preset intervals, thus meeting the requirements of different sampling points and reducing the need for manual operation. Description of the drawings
[0017] Figure 1 is a three-dimensional structural schematic diagram of the present utility model;
[0018] Figure 2 is a sectional structural schematic diagram of the present utility model;
[0019] Figure 3 is a structural schematic diagram of the intermittent rotation device of the present utility model;
[0020] Figure 4 is a structural schematic diagram of the extraction device of the present utility model.
[0021] In the figure: 1, base; 2, storage platform; 3, intermittent rotation device; 4, extraction device; 5, test tube medicine rack; 6, control computer; 7, Y-axis movement module; 8, Z-axis movement module; 9, X-axis movement module; 10, fixed bracket; 11, belt motor; 12, pulley; 13, belt; 14, support column; 15, connecting rod support block; 16, first connecting rod; 17, second connecting rod; 18, extraction module; 19, extraction module base; 20, infrared detector; 21, sampling needle; 22, reagent platform; 23, measuring cup fixing bracket; 24, dial; 25, round pin; 26, bow-shaped plate; 27, rotating column; 28, grooved wheel; 29, rotating motor; 30, extraction device bracket. Specific implementation manner
[0022] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.
[0023] Please refer to Figures 1-4 , a sampling device for biological reagents, including a base 1, a storage platform 2, an intermittent rotation device 3, an extraction device 4, a test tube medicine rack 5, a control computer 6 and a reagent platform 22. A storage platform 2 is fixedly installed at the top of the base 1. An extraction device 4 is arranged on one side of the top of the storage platform 2. A test tube medicine rack 5 is arranged on the side of the top of the storage platform 2 away from the extraction device 4. A reagent platform 22 is arranged at one end of the storage platform 2 away from the test tube medicine rack 5. The interior of the base 1 is hollow, and an intermittent rotation device 3 is arranged on the side close to the reagent platform 22 inside. A control computer 6 is fixedly installed on the side of the base 1 close to the test tube medicine rack 5; the control computer 6 controls the extraction device 4 and the intermittent rotation device 3 to work cyclically according to a preset sampling process until the sampling of all test tubes is completed, which can realize efficient and accurate sampling of biological reagents and improve the working efficiency of the laboratory.
[0024] Furthermore, the extraction device 4 includes a Y-axis movement module 7, a Z-axis movement module 8, an X-axis movement module 9 and an extraction device bracket 30. An extraction device bracket 30 is arranged on the side of the top of the storage platform 2 away from the test tube medicine rack 5. The extraction device bracket 30 is in a gate shape. A Y-axis movement module 7 is arranged on the vertical bracket on the side of the extraction device bracket 30 close to the reagent platform 22. A Z-axis movement module 8 is arranged on the top horizontal bracket of the extraction device bracket 30 away from the storage platform 2 and facing the test tube medicine rack 5. An X-axis movement module 9 is arranged on the side of the top of the storage platform 2 away from the control computer 6.
[0025] Further, the Y-axis moving module 7, the Z-axis moving module 8, and the X-axis moving module 9 include fixed brackets 10, belt motors 11, belt pulleys 12, belts 13, support columns 14, and connecting rod support blocks 15. There are two groups of fixed brackets 10. One side of the top ends of the two groups of fixed brackets 10 extends to form a Y-shaped bracket. Support columns 14 are fixedly installed at both ends of the Y-shaped bracket of the fixed bracket 10. The two groups of fixed brackets 10 are connected by two groups of support columns 14. On one side of the top end of one fixed bracket 10 away from the Y-shaped bracket, a belt motor 11 is fixedly installed, and a belt pulley 12 is fixedly installed at the corresponding other end. The belt motor 11 and the belt pulley 12 are driven by a belt 13. The Y-axis moving module 7, the Z-axis moving module 8, and the X-axis moving module 9 are all fixedly installed on the surfaces of the extraction device bracket 30 and the placement platform 2 through multiple groups of fixed brackets 10.
[0026] Further, the extraction device 4 further includes a connecting rod support block 15, a first connecting rod 16, a second connecting rod 17, and an extraction module 18. Connecting rod support blocks 15 are slidably sleeved on the support columns 14 of the Y-axis moving module 7, the Z-axis moving module 8, and the X-axis moving module 9. The bottom end of the connecting rod support block 15 is fixedly connected to the belt 13. The top end of the connecting rod support block 15 is hingedly installed with a first connecting rod 16. The other end of the first connecting rod 16 is hinged to the second connecting rod 17. The other ends of multiple groups of second connecting rods 17 are all hinged to the extraction module 18.
[0027] Further, the extraction module 18 includes an extraction module base 19, an infrared detector 20, and a sampling needle 21. The extraction module 18 is hinged to multiple groups of second connecting rods 17 through the outer surface of the extraction module base 19. A sampling needle 21 is fixedly installed at the bottom end of the extraction module base 19. Multiple groups of infrared detectors 20 are fixedly installed around the bottom end of the extraction module base 19. The multiple groups of infrared detectors 20 are distributed in a cross shape.
[0028] Further, multiple measuring cup fixing frames 23 are fixedly installed at the top end of the reagent platform 22. The bottom end of the reagent platform 22 is connected to the intermittent rotation device 3.
[0029] Further, the intermittent rotation device 3 includes a dial 24, a round pin 25, a bow-shaped plate 26, a rotating column 27, a grooved wheel 28, and a rotating motor 29. One end of the rotating motor 29 away from the output shaft is fixedly installed at the bottom end inside the base 1, and the output shaft of the rotating motor 29 is fixedly connected to the dial 24. A round pin 25 is fixedly installed on one side of the top end of the dial 24, and a bow-shaped plate 26 is fixedly installed on the side of the dial 24 away from the round pin 25. A rotating column 27 is fixedly installed at the center of the grooved wheel 28, and the rotating column 27 extends through and out of the top end of the placement platform 2 and is fixedly installed together with the reagent platform 22. An arc-shaped slot is formed inside the grooved wheel 28, and a linear slot is formed inside the arc-shaped slot. The end of the bow-shaped plate 26 away from the round pin 25 corresponds to the radian of the arc-shaped slot, and the diameter of the round pin 25 corresponds to the linear slot.
[0030] Working principle: The user places the biological reagent to be sampled on the test tube medicine rack 5, and places the corresponding measuring cup in the measuring cup fixing rack 23 of the reagent platform 22. The user sets the sampling process through the control computer 6, including parameters such as the sampling position and the sampling volume. The rotation motor 29 is started to drive the dial 24 to rotate. The round pin 25 rotates along with the dial 24. When the round pin 25 passes through the straight slot of the Geneva wheel 28, it pushes the Geneva wheel 28 to rotate a certain angle. The arc of the bow-shaped plate 26 matches the arc-shaped slot of the Geneva wheel 28 to ensure the intermittent rotation of the Geneva wheel 28. The rotation of the Geneva wheel 28 drives the rotating column 27 and the reagent platform 22 connected thereto to rotate, realizing the intermittent rotation of the measuring cup on the reagent platform 22. According to the instructions of the control computer 6, the Y-axis moving module 7, the Z-axis moving module 8, and the X-axis moving module 9 are started respectively. The belt motor 11 drives the belt 13 to rotate. Through the fixed connection between the belt 13 and the connecting rod support block 15, the connecting rod support block 15 is driven to slide on the support column 14. The sliding of the connecting rod support block 15 is converted into the three-dimensional movement of the extraction module 18 through the hinged relationship of the first connecting rod 16 and the second connecting rod 17. The extraction module 18 is accurately positioned above the test tube to be sampled through the movement of the X-axis, Y-axis, and Z-axis. When the extraction module 18 moves above the test tube, the infrared detector 20 detects the exact position of the test tube to ensure the accurate insertion of the sampling needle 21. The sampling needle 21 is inserted into the test tube to sample according to the preset sampling volume. After sampling is completed, the sampling needle 21 retracts, and the extraction module 18 moves above the corresponding measuring cup to release the sampled reagent into the measuring cup. The control computer 6 controls the extraction device 4 and the intermittent rotation device 3 to work in a cycle according to the preset sampling process until the sampling of all test tubes is completed. The device can achieve efficient and accurate sampling of biological reagents, improving the working efficiency of the laboratory. Through the combination of the intermittent rotation device and the three-dimensional mobile extraction device, the device can automatically complete the sampling of multiple test tubes, reducing the need for manual operation. The use of the infrared detector ensures that the sampling needle can be accurately inserted into the test tube, improving the accuracy of sampling. This biological reagent sampling device realizes efficient and accurate sampling of biological reagents through precise control and automated operation.
[0031] Although the embodiments of the present invention have been shown and described, it will be understood by those of ordinary skill in the art that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principles and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. A sampling device for biological reagents, comprising a base (1), a storage platform (2), an intermittent rotating device (3), an extraction device (4), a test tube drug rack (5), a control computer (6) and a reagent platform (22), characterized in that: A storage platform (2) is fixedly mounted on the top of the base (1); an extraction device (4) is arranged on one side of the top of the storage platform (2); a test tube medicine rack (5) is arranged on the side of the top of the storage platform (2) away from the extraction device (4); a reagent platform (22) is arranged on the end of the storage platform (2) away from the test tube medicine rack (5); the interior of the base (1) is hollow, and an intermittent rotating device (3) is arranged on the side of the interior close to the reagent platform (22); and a control computer (6) is fixedly mounted on the side of the base (1) close to the test tube medicine rack (5).
2. A sampling device for biological reagents according to claim 1, characterized in that: The extraction device (4) comprises a Y-axis moving module (7), a Z-axis moving module (8), an X-axis moving module (9) and an extraction device bracket (30); the extraction device bracket (30) is arranged on the side of the top of the storage platform (2) away from the test tube medicine rack (5); the extraction device bracket (30) is in the shape of a gate; the Y-axis moving module (7) is arranged on the vertical bracket on the side of the extraction device bracket (30) close to the reagent platform (22); the Z-axis moving module (8) is arranged on the side of the top horizontal bracket of the extraction device bracket (30) away from the storage platform (2) and facing the test tube medicine rack (5); and the X-axis moving module (9) is arranged on the side of the top of the storage platform (2) away from the control computer (6).
3. A sampling device for biological reagents according to claim 2, characterized in that: The Y-axis moving module (7), the Z-axis moving module (8) and the X-axis moving module (9) comprise a fixed bracket (10), a belt motor (11), a pulley (12), a belt (13), a support column (14) and a connecting rod support block (15); the fixed bracket (10) has two groups, and the top ends of the two groups of the fixed brackets (10) extend out to form a Y-shaped bracket, and the two ends of the Y-shaped bracket of the fixed bracket (10) are respectively fixedly installed with a support column (14), and the two groups of the fixed brackets (10) are connected through Through the two groups of support columns (14), a belt motor (11) is fixedly installed on the side of the top of the fixed bracket (10) at one end away from the Y-shaped bracket, and a pulley (12) is fixedly installed at the other end. The belt motor (11) and the pulley (12) are driven by a belt (13). The Y-axis moving module (7), the Z-axis moving module (8) and the X-axis moving module (9) are all fixedly installed on the surface of the extraction device bracket (30) and the storage platform (2) through multiple groups of fixed brackets (10).
4. A sampling device for biological reagents according to claim 3, characterized in that: The extraction device (4) further comprises a connecting rod support block (15), a first connecting rod (16), a second connecting rod (17) and an extraction module (18); the supporting columns (14) of the Y-axis moving module (7), the Z-axis moving module (8) and the X-axis moving module (9) are all slidably sleeved with the connecting rod support block (15); the bottom end of the connecting rod support block (15) is fixedly connected to the belt (13); the top end of the connecting rod support block (15) is hingedly mounted with the first connecting rod (16); the other end of the first connecting rod (16) is hingedly connected to the second connecting rod (17); and the other ends of multiple groups of the second connecting rods (17) are hingedly connected to the extraction module (18).
5. A sampling device for biological reagents according to claim 4, characterized in that: The extraction module (18) comprises an extraction module base (19), an infrared detector (20) and a sampling needle (21); the extraction module (18) is hinged with a plurality of second connecting rods (17) respectively through the surface of the outer side of the extraction module base (19); the sampling needle (21) is fixedly mounted on the bottom end of the extraction module base (19); and a plurality of infrared detectors (20) are fixedly mounted around the bottom end of the extraction module base (19); the plurality of infrared detectors (20) are distributed in a cross shape.
6. A sampling device for biological reagents according to claim 1, characterized in that: A plurality of groups of measuring cup fixing frames (23) are fixedly mounted on the top of the reagent platform (22), and the bottom of the reagent platform (22) is connected to the intermittent rotating device (3).
7. A sampling device for biological reagents according to claim 1, characterized in that: The intermittent rotating device (3) comprises a dial (24), a round pin (25), a bow plate (26), a rotating column (27), a groove wheel (28) and a rotating motor (29), wherein one end of the rotating motor (29) away from the output shaft is fixedly mounted at the bottom end inside the base (1), the output shaft of the rotating motor (29) is fixedly connected to the dial (24), a round pin (25) is fixedly mounted on one side of the top end of the dial (24), and the dial (24) away from the round pin (25) A bow plate (26) is fixedly installed on one side of the groove wheel (28), a rotating column (27) is fixedly installed at the center of the groove wheel (28), and the rotating column (27) extends through the top of the storage platform (2) and is fixedly installed together with the reagent platform (22). An arc groove is provided inside the groove wheel (28), and a straight groove is provided inside the arc groove. The end of the bow plate (26) away from the round pin (25) corresponds to the arc of the arc groove, and the round pin (25) corresponds to the diameter of the straight groove.