Raman detection reagent carrier

Abstract

The utility model discloses a Raman detection reagent carrying frame, which relates to the field of biomedicine and comprises a carrying sheet used for carrying a sample; the separation sleeve is tightly adsorbed on the surfaces of the separation sleeve and the slide glass, a plurality of separation cavities are formed in the separation sleeve, and sample reserving holes are formed in the bottoms of the separation cavities, so that each sample slice can be independently and stably placed on the slide glass through the design of the separation cavities in the separation sleeve. By means of the flat and separated placing mode, mutual contact and interference among the slices are effectively avoided, accuracy and reliability of detection results are guaranteed, the cover pressing piece, the sleeve shell and the optional top cover jointly form a hard outer shell, and a dust-free and pollution-free culture or storage environment is provided for the sample slices.

Description

Technical Field

[0001] The utility model relates to the field of biomedicine, in particular to a Raman detection reagent carrier. Background Art

[0002] Raman detection is an inelastic scattering spectroscopy technology. When the laser irradiates the sample, it interacts with the molecules in the sample to produce scattered light. Part of this scattered light is Raman scattered light, which is closely related to the molecular structure of the sample. By analyzing and interpreting the Raman scattered light, the molecular structure and chemical information of the sample can be obtained. Traditional Raman detection methods require multiple steps when dealing with complex samples, especially biological samples, including sample collection, fixation, embedding, slicing, patching, and washing. Traditional sample carriers have certain shortcomings, such as loose sample fixation and offset of slices during placement, which affects the accuracy of the test results. These problems not only reduce the accuracy of the test data, but also increase the complexity and time cost of experimental operations. Utility Model Content

[0003] The utility model aims to provide a Raman detection reagent carrier, which solves the following technical problems: how to ensure the stable placement and effective isolation of sample slices, and how to reduce the interference of external pollutants on the samples.

[0004] In order to solve the problems existing in the prior art, the technical solution adopted by the utility model is as follows:

[0005] A Raman detection reagent carrier, comprising a carrier sheet, the carrier sheet being used to carry a sample;

[0006] The separation sleeve is tightly adsorbed on the surface of the slide, a plurality of separation chambers are arranged inside the separation sleeve, and sample retention holes are arranged at the bottom of the separation chambers.

[0007] Preferably, grooves are symmetrically provided on both sides of the sample retention hole at the bottom of the separation chamber.

[0008] Preferably, the outer side of the bottom of the carrier is slidably connected with a bottom shell, the top of the carrier is provided with a cover pressing plate, the cover pressing plate is embedded in the bottom shell, the top of the cover pressing plate is provided with a sleeve shell, and the sleeve shell is sleeved on the outside of the separation sleeve.

[0009] Preferably, two sides of the bottom shell are rotatably connected with C-shaped buckle pieces, and the buckle pieces are respectively sleeved on two sides of the carrier sheet and the cover pressing sheet.

[0010] Preferably, the top of the cover pressing plate is symmetrically provided with convex strips, and the top lower surface of the buckle plate is correspondingly provided with a limiting strip for engaging with the convex strips.

[0011] Preferably, a top cover is slidably mounted on the top of the casing.

[0012] Preferably, a detection opening is provided at the bottom of the bottom case, and the detection opening is disposed opposite to the separation cavity.

[0013] Compared with the related art, the utility model has the following beneficial effects:

[0014] Through the design of the separation cavity in the separation sleeve, each sample section can be independently and stably placed on the slide. This flat and separated placement method effectively avoids the mutual contact and interference between the sections, ensuring the accuracy and reliability of the detection results. The cover pressing piece, the sleeve case and the optional top cover together constitute a hard shell, providing a dust-free and pollution-free culture or storage environment for the sample sections. This closed design effectively prevents the invasion of external pollutants to the sample sections, ensuring the purity of the samples and the accuracy of the detection results. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 is a schematic diagram of the overall structure of the utility model;

[0016] Figure 2 is a schematic diagram of the structure of the separation sleeve of the utility model;

[0017] Figure 3 is a schematic diagram of the bottom structure of the separation sleeve of the utility model;

[0018] Figure 4 is a schematic diagram of the structure of the cover pressing piece and the sleeve case of the utility model;

[0019] Figure 5 is a schematic diagram of the bottom case structure of the utility model.

[0020] Reference numerals: 1, slide; 2, separation sleeve; 21, separation cavity; 22, sample retention hole; 23, groove; 3, bottom case; 4, cover pressing piece; 41, rib; 5, sleeve case; 31, detection opening; 6, buckle piece; 61, limiting strip; 7, top cover. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0021] In order to make the purpose, technical solutions and advantages of the utility model more clear and understandable, the following further describes the utility model in detail with reference to the accompanying drawings and embodiments.

[0022] As Figures 1 to 5 shown, the Raman detection reagent carrier has a slide 1 and a separation sleeve 2; the slide 1 is used to carry samples, the separation sleeve 2 is tightly adsorbed on the surface of the slide 1, and a plurality of separation cavities 21 are provided inside the separation sleeve 2, and sample retention holes 22 are provided at the bottoms of the separation cavities 21.

[0023] The separation sleeve 2 is made of a soft rubber material and can be firmly adsorbed on the surface of the slide 1. The separation cavities 21 on the separation sleeve 2 are used to place the sample sections on the slide 1 in a flat and separated manner, ensuring that each section can be placed independently and stably therein. There is enough space between the separation cavities 21 to prevent the sections from contacting and interfering with each other, and a sample-retaining hole 22 is provided at the bottom of the separation cavity 21 for the flat attachment and placement of the sections. When detecting, as long as the separation sleeve 2 is gently pulled, it can be removed from the slide 1.

[0024] As Figures 1 to 5 shown, grooves 23 are symmetrically provided on both sides of the sample-retaining hole 22 at the bottom of the separation cavity 21, and the grooves 23 can make the separation sleeve 2 more firmly adsorbed on the slide 1.

[0025] As Figures 1 to 5 shown, a bottom shell 3 is slidably connected to the outside of the bottom of the slide 1, a cover pressing piece 4 is provided on the top of the slide 1, the cover pressing piece 4 is embedded inside the bottom shell 3, a sleeve shell 5 is provided on the top of the cover pressing piece 4, and the sleeve shell 5 is sleeved outside the separation sleeve 2. The cover pressing piece 4 is a plastic thin sheet with the same width as the slide 1, and a hole with the same shape as the separation sleeve 2 is left in the middle;

[0026] As Figures 1 to 5 shown, C-shaped bent buckle pieces 6 are rotatably connected to both sides of the bottom shell 3, and the buckle pieces 6 are respectively sleeved on both sides of the slide 1 and the cover pressing piece 4;

[0027] As Figures 1 to 5 shown, convex strips 41 are symmetrically provided on the top of the cover pressing piece 4, and limiting strips 61 for engaging with the convex strips 41 are correspondingly provided on the lower surface of the top of the buckle piece 6.

[0028] The buckle pieces 6 can be respectively sleeved on both sides of the slide 1 and the cover pressing piece 4, and are rotationally fastened to achieve a tight connection between the slide 1 and the cover pressing piece 4. At the same time, the convex strips 41 symmetrically provided on the top of the cover pressing piece 4 and the limiting strips 61 on the lower surface of the top of the buckle piece 6 are engaged with each other, increasing the stability and reliability of the connection.

[0029] As Figures 1 to 5 shown, a top cover 7 is slidably sleeved on the top of the sleeve shell 5;

[0030] A rigid outer shell is formed among the sleeve shell 5, the cover pressing piece 4 and the bottom shell 3, and the top cover 7 is still slidably sleeved on the top of the sleeve shell 5. When needed, the top cover 7 can be covered to form a closed cavity, providing a dust-free and pollution-free culture or storage environment for the sample sections.

[0031] As Figures 1 to 5 shown, a detection port 31 is opened at the bottom of the bottom shell 3, and the detection port 31 is disposed opposite to the separation cavity 21. Through the detection port 31, the state of the sample sections in the separation cavity 21 can be conveniently observed from below the slide 1, preparing for subsequent Raman detection.

[0032] Although embodiments of the present utility model have been shown and described, those of ordinary skill in the art can understand that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principles and spirit of the present utility model. The scope of the present utility model is defined by the appended claims and their equivalents.

Claims

1. A Raman detection reagent carrier, characterized in that: include: A slide (1), the slide (1) is used to carry a sample; A separation sleeve (2), the separation sleeve (2) is tightly adsorbed on the surface of the slide (1), a plurality of separation chambers (21) are arranged inside the separation sleeve (2), and sample retention holes (22) are arranged at the bottom of each separation chamber (21); The bottom of the separation chamber (21) is symmetrically provided with grooves (23) on both sides of the sample retention hole (22); The bottom outer side of the carrier (1) is slidably connected to a bottom shell (3), the top of the carrier (1) is provided with a cover pressing sheet (4), the cover pressing sheet (4) is embedded in the bottom shell (3), the top of the cover pressing sheet (4) is provided with a sleeve shell (5), and the sleeve shell (5) is sleeved on the outside of the separation sleeve (2).

2. The Raman detection reagent carrier according to claim 1, characterized in that: The two sides of the bottom shell (3) are rotatably connected with C-shaped bent buckle plates (6), and the buckle plates (6) are respectively sleeved on the two sides of the carrier plate (1) and the cover pressing plate (4).

3. The Raman detection reagent carrier according to claim 2, characterized in that: The top of the cover pressing plate (4) is symmetrically provided with convex strips (41), and the lower surface of the top of the buckle plate (6) is correspondingly provided with a limiting strip (61) for engaging with the convex strip (41).

4. The Raman detection reagent carrier according to claim 1, characterized in that: A top cover (7) is slidably mounted on the top of the casing (5).

5. The Raman detection reagent carrier according to claim 1, characterized in that: The bottom of the bottom shell (3) is provided with a detection port (31), and the detection port (31) is arranged opposite to the separation cavity (21).

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