Efficient nucleic acid extraction and adsorption column

Abstract

The utility model discloses an efficient nucleic acid extraction adsorption column, which belongs to the technical field of medical instruments and is characterized by comprising an outer barrel and a base, an inner barrel is arranged in the outer barrel, a barrel cover for sealing the inner barrel is arranged at the top end of the inner barrel, and a silica gel adsorption material is arranged in the inner barrel. The top of the base is provided with a mounting cavity for placing the outer barrel, an elastic component for stably placing the outer barrel is arranged in the mounting cavity, and a rotating component is arranged at the bottom of the base. According to the utility model, the outer cylinder body is placed in the mounting cavity formed in the base, then the outer cylinder body is pressed and fixed through the elastic component, and then the outer cylinder body is rotated to drive the base to rotate in the rotating component, so that a sample in the outer cylinder body is rapidly separated and extracted, the use is simple and convenient, and the working efficiency is improved. And the extraction efficiency is effectively improved.

Description

Technical Field

[0001] The utility model belongs to the technical field of medical appliances, and particularly relates to an efficient nucleic acid extraction adsorption column. Background Art

[0002] Nucleic acid extraction is one of the basic operations in molecular biology experiments. Its purpose is to isolate pure nucleic acid (DNA or RNA) from biological samples for subsequent analysis and research. Traditional nucleic acid extraction methods usually involve multiple steps, such as cell lysis, protein removal, nucleic acid precipitation, etc., which are cumbersome and time-consuming.

[0003] In recent years, nucleic acid extraction adsorption columns have gradually attracted attention as a fast and convenient nucleic acid extraction tool. Nucleic acid extraction adsorption columns use specific adsorption materials (such as silica gel, diatomite, etc.) to selectively adsorb nucleic acids, thereby realizing the rapid separation and purification of nucleic acids. However, there is still room for improvement in the structural design and operation convenience of existing nucleic acid extraction adsorption columns. Therefore, the present invention provides a novel nucleic acid extraction adsorption column to improve the efficiency and quality of nucleic acid extraction. Content of the Utility Model

[0004] The purpose of the utility model is to provide an efficient nucleic acid extraction adsorption column to solve the problems raised in the above background art.

[0005] To achieve the above purpose, the utility model provides the following technical solution: an efficient nucleic acid extraction adsorption column, including an outer cylinder and a base. An inner cylinder is arranged inside the outer cylinder. A cylinder cover for closing the inner cylinder is arranged at the top of the inner cylinder. The inside of the inner cylinder is provided with a silica gel adsorption material. An installation chamber for placing the outer cylinder is opened at the top of the base. An elastic member for stably placing the outer cylinder is arranged inside the installation chamber. A rotating member is arranged at the bottom of the base.

[0006] Preferably, the elastic member is a soft pad, and the soft pad stands in a ring groove opened on the circumferential inner wall of the base.

[0007] Preferably, the inner circle of the soft pad is an arc-shaped structure.

[0008] Preferably, the rotating member is a support ring, and the support ring is rotatably connected in a support groove opened at the bottom of the base. A lubrication assembly is arranged between the support ring and the support groove.

[0009] Preferably, the lubrication assembly includes a plurality of support balls, and the plurality of support balls are all rotatably connected in an installation groove opened at the top of the support ring.

[0010] Preferably, an auxiliary support ring is arranged on the circumferential outer wall of the support ring.

[0011] Preferably, both the outer cylinder and the inner cylinder are made of transparent or translucent plastic or glass materials.

[0012] Compared with the prior art, the beneficial effects of the present utility model are as follows: Add the sample to be extracted into the sampling port of the inner cylinder, adsorb nucleic acid through the adsorption material inside the inner cylinder, then collect the extracted nucleic acid through the sample outlet, then place the outer cylinder in the installation chamber opened in the base, and then make it be tightly fixed through the elastic component, and then rotate the outer cylinder. The outer cylinder drives the base to rotate within the rotating component, so that the sample in the outer cylinder can be quickly separated and extracted, which is not only simple and convenient to use, but also effectively improves the extraction efficiency. Description of the Drawings

[0013] Figure 1 is a perspective view of the present utility model;

[0014] Figure 2 is the present utility model Figure 1 exploded view;

[0015] Figure 3 is a partial exploded view of the present utility model;

[0016] Figure 4 is a sectional view of the base of the present utility model.

[0017] In the figure: 1. Outer cylinder; 2. Base; 3. Cylinder cover; 4. Inner cylinder; 5. Installation chamber; 6. Support ring; 7. Support ball; 8. Installation groove; 9. Auxiliary support ring; 10. Ring groove; 11. Soft pad; 12. Support groove. Detailed Embodiment

[0018] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all of the embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present utility model.

[0019] Please refer to Figures 1-4, the present utility model provides an efficient nucleic acid extraction adsorption column, which includes an outer cylinder body 1 and a base 2. An inner cylinder body 4 is arranged inside the outer cylinder body 1. A cylinder cover 3 for closing the inner cylinder body 4 is arranged at the top of the inner cylinder body 4. A silica gel adsorption material is arranged inside the inner cylinder body 4. An installation chamber 5 for placing the outer cylinder body 1 is opened at the top of the base 2. An elastic member for making the placement of the outer cylinder body 1 stable is arranged inside the installation chamber 5. A rotating member is arranged at the bottom of the base 2. Add the sample to be extracted into the sample inlet of the inner cylinder body 4, adsorb the nucleic acid through the adsorption material inside the inner cylinder body 4, then collect the extracted nucleic acid through the sample outlet, then place the outer cylinder body 1 inside the installation chamber 5 opened in the base 2, and then make it be pressed and fixed through the elastic member, and then rotate the outer cylinder body 1. The outer cylinder body 1 drives the base 2 to rotate inside the rotating member, so as to quickly separate and extract the sample inside the outer cylinder body 1. It is not only simple and convenient to use, but also effectively improves the extraction efficiency.

[0020] In this embodiment, the elastic member is a soft pad 11. The soft pad 11 stands in the annular groove 10 opened on the circumferential inner wall of the base 2, so as to squeeze the outer cylinder body 1 through the soft pad 11 and increase the friction between the outer cylinder body 1 and the base 2, thereby fixing the outer cylinder body 1.

[0021] In this embodiment, the inner ring of the soft pad 11 is of an arc-shaped structure, which is convenient for the outer cylinder body 1 to be clamped into the soft pad 11.

[0022] In this embodiment, the rotating member is a support ring 6. The support ring 6 is rotatably connected in the support groove 12 opened at the bottom of the base 2. A lubricating component is arranged between the support ring 6 and the support groove 12. The lubricating component includes a plurality of support balls 7. The plurality of support balls 7 are all rotatably connected in the installation groove 8 opened at the top of the support ring 6. Then, the rotation generated by the support balls 7 greatly reduces the friction between the base 2 and the support ring 6.

[0023] In this embodiment, an auxiliary support ring 9 is arranged on the circumferential outer wall of the support ring 6. The contact area between the support ring 6 and the tabletop is greatly increased through the auxiliary support ring 9, thereby improving the stability of the support ring 6.

[0024] In this embodiment, both the outer cylinder body 1 and the inner cylinder body 4 are made of transparent or semi-transparent plastic or glass materials.

[0025] Working principle and usage process of the present utility model: During use, the sample to be extracted is added into the sample inlet of the inner cylinder 4, the nucleic acid is adsorbed by the adsorption material inside the inner cylinder 4, and then the extracted nucleic acid is collected through the sample outlet. Then, the outer cylinder 1 is placed in the installation chamber 5 opened in the base 2, and then the outer cylinder 1 is extruded by the soft pad 11, and the friction between the outer cylinder 1 and the base 2 is increased, so that the outer cylinder 1 is fixed. Then, the outer cylinder 1 is rotated, and the outer cylinder 1 drives the base 2 to rotate in the support ring 6, and the rotation generated by the support balls 7 greatly reduces the friction between the base 2 and the support ring 6, so that the sample in the outer cylinder 1 is quickly separated and extracted. It is not only simple and convenient to use, but also effectively improves its extraction efficiency.

[0026] The electronic components and modules used in the content of this utility model can all be parts commonly used in the current market and can realize the specific functions in this case, and the specific models and sizes can be selected and adjusted according to actual needs.

[0027] The above shows and describes the basic principles, main features and advantages of the present utility model. Those skilled in the art should understand that the present utility model is not limited by the above embodiments. What is described in the above embodiments and the specification only illustrates the principle of the present utility model. Without departing from the spirit and scope of the present utility model, the present utility model will have various changes and improvements, and these changes and improvements all fall within the scope of the present utility model claimed. The scope of protection claimed by the present utility model is defined by the appended claims and their equivalents.

Claims

1. An efficient nucleic acid extraction adsorption column, comprising an outer cylinder (1) and a base (2), wherein an inner cylinder (4) is arranged inside the outer cylinder (1), a cylinder cover (3) is arranged at the top of the inner cylinder (4) to seal the inner cylinder (4), and a silica gel adsorption material is arranged inside the inner cylinder (4), characterized in that: The top of the base (2) is provided with an installation chamber (5) for placing the outer cylinder (1), and an elastic component for placing the outer cylinder (1) firmly is provided in the installation chamber (5). The bottom of the base (2) is provided with a rotating component.

2. The high-efficiency nucleic acid extraction adsorption column according to claim 1, characterized in that: The elastic component is a soft cushion (11), and the soft cushion (11) is placed in an annular groove (10) formed on the inner circumferential wall of the base (2).

3. The high-efficiency nucleic acid extraction adsorption column according to claim 2, characterized in that: The inner circle of the soft cushion (11) is an arc-shaped structure.

4. The high-efficiency nucleic acid extraction adsorption column according to claim 1, characterized in that: The rotating component is a support ring (6), which is rotatably connected to a support groove (12) provided at the bottom of the base (2), and a lubrication component is provided between the support ring (6) and the support groove (12).

5. The high-efficiency nucleic acid extraction adsorption column according to claim 4, characterized in that: The lubrication assembly comprises a plurality of supporting balls (7), and the plurality of supporting balls (7) are all rotatably connected in a mounting groove (8) provided at the top of the supporting ring (6).

6. The high-efficiency nucleic acid extraction adsorption column according to claim 5, characterized in that: An auxiliary support ring (9) is provided on the circumferential outer wall of the support ring (6).

7. The high-efficiency nucleic acid extraction adsorption column according to claim 1, characterized in that: The outer cylinder (1) and the inner cylinder (4) are both made of transparent or translucent plastic or glass.

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