Purification device for stem cells

Abstract

The utility model discloses a purification device for stem cells, which comprises a table top and a first cover body, a motor is fixed at the center of the top of the table top, a first gear is fixed at the output end of the top of the motor, a second gear is meshed with one side of the first gear, a rotating shaft is fixed in the middle of the second gear in a penetrating manner, and a first cover body is fixed on the rotating shaft. According to the purification device for the stem cells, the motor is started, the motor can drive the multiple sets of storage barrels and the cylindrical filter screen to rotate at the same time through the first gear, and under the action of centrifugal force, the storage barrels and the cylindrical filter screen are driven to rotate at the same time; the stem cell suspension in the barrel-shaped filter screen is filtered by the barrel-shaped filter screen and enters the storage barrel, and large tissues in the stem cell suspension are left in the barrel-shaped filter screen, so that multiple groups of stem cell suspensions can be simultaneously filtered and purified, and the working efficiency is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of stem cell processing, in particular to a purification device for stem cells. Background Technique

[0002] With the development of modern biomedicine, the culture of stem cells plays an indispensable role in biomedical research. Stem cell purification is the process of obtaining a single type of cell from a heterogeneous cell suspension with mixed components before primary culture or from a culture.

[0003] Usually, when purifying a stem cell suspension, it is necessary to filter and purify the undigested tissue in the stem cell suspension. However, the existing stem cell purification devices can only filter and purify one group of stem cell suspensions at a time, and cannot filter and purify multiple groups of stem cell suspensions simultaneously, resulting in low work efficiency. Moreover, it is not convenient to disassemble the filter net for cleaning, which also affects the work efficiency.

[0004] In view of the above problems, there is an urgent need to innovate and design on the basis of the original stem cell purification device. Content of the Utility Model

[0005] The purpose of the utility model is to provide a purification device for stem cells to solve the problems raised in the above background technique.

[0006] To achieve the above purpose, the utility model provides the following technical solution: A purification device for stem cells, including a tabletop and a first cover body. A motor is fixed at the center of the top of the tabletop. The output end of the top of the motor is fixed with a first gear. A second gear is meshed on one side of the first gear. A rotating shaft is fixedly penetrated through the middle of the second gear. The lower end of the rotating shaft is rotationally connected to the top of the tabletop through a bearing. The upper end of the rotating shaft is fixed with a storage barrel;

[0007] The bottom of the first cover body is provided with a first thread groove. The center of the top of the first thread groove is provided with a second thread groove. The center of the top of the second thread groove is provided with a third thread groove. The first cover body is connected to the storage barrel through the first thread groove. A fixing ring is installed inside the second thread groove. A cylindrical filter net is fixed at the bottom of the fixing ring. The bottom of a second cover body is installed inside the third thread groove, and the top of the second cover body is located above the first cover body.

[0008] Preferably, a sealing ring is fixed at the bottom of the upper half of the second cover body. The bottom of the sealing ring is in contact with the top of the first cover body. The lower half of the second cover body is in threaded connection with the third thread groove.

[0009] Preferably, a discharge pipe is arranged at the bottom of one side of the storage barrel. A manual valve is installed on the discharge pipe.

[0010] Preferably, the outer wall of the top of the storage cylinder is threadedly connected to the first thread groove, and another sealing ring is fixed to the top of the storage cylinder, and the top of another sealing ring is in contact with the top of the first thread groove.

[0011] Preferably, the second thread groove is threadedly connected to the outer wall of the top of the fixing ring.

[0012] Preferably, the second gear, the rotating shaft, the storage cylinder, the first cover body, the first thread groove, the second thread groove, the third thread groove, the fixing ring, the cylindrical filter screen, the second cover body and the sealing ring are all equally angularly distributed about the central axis of the first gear.

[0013] Compared with the prior art, the beneficial effects of the present utility model are as follows: For the purification device for stem cells, by starting the motor, the motor can drive multiple groups of storage cylinders and cylindrical filter screens to rotate simultaneously through the first gear. Under the action of centrifugal force, the stem cell suspension inside the cylindrical filter screen passes through the filtration of the cylindrical filter screen and enters the inside of the storage cylinder, and the large pieces of tissue in the stem cell suspension remain inside the cylindrical filter screen, so that multiple groups of stem cell suspensions can be filtered and purified simultaneously, improving the working efficiency;

[0014] Since the first cover body is threadedly connected to both the storage cylinder and the fixing ring, it is convenient to disassemble the cylindrical filter screen from the inside of the storage cylinder for cleaning. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 is a front sectional structure schematic diagram of the present utility model;

[0016] Figure 2 is the present utility model Figure 1 the enlarged structure schematic diagram at A in

[0017] Figure 3 is a top view distribution structure schematic diagram of the first cover body of the present utility model;

[0018] Figure 4 is a top view distribution structure schematic diagram of the second gear of the present utility model;

[0019] Figure 5 is a top view installation structure schematic diagram of the first cover body of the present utility model;

[0020] Figure 6 is a bottom view installation structure schematic diagram of the fixing ring of the present utility model.

[0021] In the figure: 1, tabletop; 2, motor; 3, first gear; 4, second gear; 5, rotating shaft; 6, material storage cylinder; 7, first cover; 8, first thread groove; 9, second thread groove; 10, third thread groove; 11, fixing ring; 12, cylindrical filter screen; 13, second cover; 14, sealing ring; 15, discharge pipe; 16, manual valve. Detailed implementation manners

[0022] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0023] Please refer to Figures 1-6 , the present invention provides a technical solution: a purification device for stem cells, including a tabletop 1 and a first cover 7. A motor 2 is fixed at the center of the top of the tabletop 1. The output end at the top of the motor 2 is fixed with a first gear 3. A second gear 4 is meshed on one side of the first gear 3. A rotating shaft 5 is fixedly penetrated through the middle of the second gear 4. The lower end of the rotating shaft 5 is rotationally connected to the top of the tabletop 1 through a bearing. The upper end of the rotating shaft 5 is fixed with a material storage cylinder 6;

[0024] The bottom of the first cover 7 is provided with a first thread groove 8. The center of the top of the first thread groove 8 is provided with a second thread groove 9. The center of the top of the second thread groove 9 is provided with a third thread groove 10. The first cover 7 is connected to the material storage cylinder 6 through the first thread groove 8. A fixing ring 11 is installed inside the second thread groove 9. The bottom of the fixing ring 11 is fixed with a cylindrical filter screen 12. The bottom of a second cover 13 is installed inside the third thread groove 10, and the top of the second cover 13 is located above the first cover 7.

[0025] A sealing ring 14 is fixed at the bottom of the upper half of the second cover 13. The bottom of the sealing ring 14 is in contact with the top of the first cover 7. The lower half of the second cover 13 is threadedly connected to the third thread groove 10, which increases the sealing performance at the connection between the second cover 13 and the first cover 7 and prevents the stem cell suspension inside the material storage cylinder 6 from leaking out from the connection between the second cover 13 and the first cover 7.

[0026] A discharge pipe 15 is provided at the bottom of one side of the material storage cylinder 6. A manual valve 16 is installed on the discharge pipe 15, which facilitates the opening and closing of the discharge pipe 15 and enables the filtered stem cell suspension inside the material storage cylinder 6 to be discharged.

[0027] The outer wall of the top of the storage cylinder 6 is threadedly connected to the first thread groove 8. Another sealing ring 14 is fixed to the top of the storage cylinder 6. The top of the another sealing ring 14 is in contact with the top of the first thread groove 8, which increases the sealing performance at the connection between the storage cylinder 6 and the first cover body 7 and prevents the stem cell suspension inside the storage cylinder 6 from leaking out from the connection between the storage cylinder 6 and the first cover body 7.

[0028] The second thread groove 9 is threadedly connected to the outer wall of the top of the fixing ring 11, which facilitates the disassembly of the fixing ring 11 and the cylindrical filter net 12 from the first cover body 7 for cleaning.

[0029] The second gear 4, the rotating shaft 5, the storage cylinder 6, the first cover body 7, the first thread groove 8, the second thread groove 9, the third thread groove 10, the fixing ring 11, the cylindrical filter net 12, the second cover body 13 and the sealing ring 14 are all equally angularly distributed about the central axis of the first gear 3, ensuring that when the first gear 3 rotates, the first gear 3 can drive multiple sets of the second gear 4, the rotating shaft 5, the storage cylinder 6, the first cover body 7, the first thread groove 8, the second thread groove 9, the third thread groove 10, the fixing ring 11, the cylindrical filter net 12, the second cover body 13 and the sealing ring 14 to rotate simultaneously.

[0030] Working principle: When using the purification device for stem cells, first rotate the second cover body 13. Since the second cover body 13 is threadedly connected to the third thread groove 10, the second cover body 13 is disassembled. Then, the stem cell suspension is put into the inside of the cylindrical filter net 12 through the third thread groove 10, the second thread groove 9 and the first thread groove 8. The bottom of the second cover body 13 is reinstalled by rotating it inside the third thread groove 10. By the same principle, the stem cell suspension is put into the inside of other storage cylinders 6;

[0031] Then start the motor 2. Next, the motor 2 drives the first gear 3 to rotate. Then, the first gear 3 drives multiple sets of the second gear 4, the rotating shaft 5, the storage cylinder 6, the first cover body 7, the first thread groove 8, the second thread groove 9, the third thread groove 10, the fixing ring 11, the cylindrical filter net 12, the second cover body 13 and the sealing ring 14 to rotate simultaneously. Under the action of centrifugal force, the stem cell suspension inside the cylindrical filter net 12 passes through the filtration of the cylindrical filter net 12 and enters the inside of the storage cylinder 6. The large pieces of tissue in the stem cell suspension remain inside the cylindrical filter net 12, so that multiple sets of stem cell suspensions can be filtered and purified simultaneously, improving the working efficiency;

[0032] When the cylindrical filter net 12 needs to be disassembled for cleaning, rotate the first cover body 7. Since the first cover body 7 is threadedly connected to the first thread groove 8, the first cover body 7 is disassembled from the storage barrel 6. Then, through the first cover body 7, the fixing ring 11 and the cylindrical filter net 12 are taken out from the inside of the storage barrel 6. Then, rotate the fixing ring 11. Since the fixing ring 11 is threadedly connected to the second thread groove 9, the fixing ring 11 and the cylindrical filter net 12 can be disassembled, facilitating the disassembly of the cylindrical filter net 12 for cleaning.

[0033] Although the present invention has been described in detail with reference to the foregoing embodiments, for those skilled in the art, they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements on some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A stem cell purification device, comprising a table (1) and a first cover (7), characterized in that: A motor (2) is fixed at the center of the top of the table (1); a first gear (3) is fixed to the output end of the top of the motor (2); a second gear (4) is meshed with one side of the first gear (3); a rotating shaft (5) is fixed through the middle of the second gear (4); the lower end of the rotating shaft (5) is rotatably connected to the top of the table (1) via a bearing; and a material storage barrel (6) is fixed to the upper end of the rotating shaft (5); The first cover body (7) is provided with a first thread groove (8) at the bottom, a second thread groove (9) is provided at the center of the top of the first thread groove (8), a third thread groove (10) is provided at the center of the top of the second thread groove (9), the first cover body (7) is connected to the storage barrel (6) via the first thread groove (8), a fixing ring (11) is installed inside the second thread groove (9), a cylindrical filter screen (12) is fixed to the bottom of the fixing ring (11), the bottom of the second cover body (13) is installed inside the third thread groove (10), and the top of the second cover body (13) is located above the first cover body (7).

2. A stem cell purification device according to claim 1, characterized in that: A sealing ring (14) is fixed to the bottom of the upper part of the second cover body (13), the bottom of the sealing ring (14) is in contact with the top of the first cover body (7), and the lower part of the second cover body (13) is threadedly connected to the third thread groove (10).

3. A stem cell purification device according to claim 1, characterized in that: A discharge pipe (15) is provided at the bottom of one side of the storage barrel (6), and a manual valve (16) is installed on the discharge pipe (15).

4. A stem cell purification device according to claim 2, characterized in that: The outer wall of the top of the storage barrel (6) is threadedly connected to the first thread groove (8), and another sealing ring (14) is fixed to the top of the storage barrel (6), and the top of the other sealing ring (14) is in contact with the top of the first thread groove (8).

5. A stem cell purification device according to claim 1, characterized in that: The second thread groove (9) is threadably connected to the outer wall of the top of the fixing ring (11).

6. A stem cell purification device according to claim 1, characterized in that: The second gear (4), the rotating shaft (5), the material storage barrel (6), the first cover body (7), the first thread groove (8), the second thread groove (9), the third thread groove (10), the fixing ring (11), the cylindrical filter screen (12), the second cover body (13) and the sealing ring (14) are all distributed at equal angles with respect to the central axis of the first gear (3).

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