Auxiliary experiment device for measuring heparin content in human prothrombin complex
By designing an auxiliary experimental device including a vibrator and lighting lamp, automatically shaking and providing fill light, the problem of hand fatigue and observation difficulties caused by manually shaking the test tube holder when determining the heparin content in the human prothrombin complex is solved, and more efficient and convenient experimental operations are achieved.
Patent Information
- Application Number
- CN202421915136.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-08-08
- Publication Date
- 2025-06-27
- Estimated Expiration
- 2034-08-08
AI Technical Summary
When using the coagulation method to determine the heparin content in the human prothrombin complex, the experimenter needs to shake the test tube holder manually for a long time, resulting in hand fatigue and inconvenient observation of the liquid solidification in the test tube.
An auxiliary experimental device was designed, including a vibrator, a test tube stand and a lighting lamp. The vibrator automatically shakes the reaction reagents and samples to be inspected in the test tube. The lighting lamp provides fill light to facilitate experimenters to observe the solidification of the liquid.
Through automatic shaking and fill light functions, the hands of the experimenters are liberated, the fatigue of manual operation is reduced, and the convenience and accuracy of observing the solidification of the liquid in the test tube is improved.
Smart Images
Figure CN223027187U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to an auxiliary experimental device for measuring the heparin content in human prothrombin complex, belonging to the technical field of experimental devices. Background Technique
[0002] Human prothrombin complex concentrate (PCC) is widely used in the treatment of clinical indications such as deficiency of coagulation factors II, VII, IX, and X, anticoagulant overdose, vitamin K deficiency, bleeding patients with liver diseases who need to correct coagulation dysfunction, prothrombin time prolongation caused by various reasons and intended for surgical operations, and bleeding symptoms of hemophilia A patients with factor VIII inhibitors. And some PCC products will add a certain amount of heparin. The third part of the Chinese Pharmacopoeia (2015 edition)… PCC stipulates the requirements for the heparin content in the corresponding products, as well as the determination method of heparin, that is, the protamine sulfate neutralization heparin coagulation method. This method is based on the principle that protamine sulfate can neutralize heparin, thereby affecting the plasma coagulation time, and measures the heparin content in the test sample. This method has good repeatability, and the sample after neutralizing heparin can be directly used for the determination of thrombin activity, FIX titer, and activated coagulation factors.
[0003] However, when using the coagulation method to measure the heparin content in human prothrombin complex, it is necessary for experimenters to manually shake the test tube rack for a long time to achieve the purpose of shaking multiple test tubes on the test tube rack, and observe the coagulation situation of the liquid in each test tube during this process. There are deficiencies that the experimenter's hand is prone to fatigue and it is not convenient to observe the coagulation situation of the liquid in the test tube. Content of the Utility Model
[0004] To solve the above technical problems, the utility model provides an auxiliary experimental device for measuring the heparin content in human prothrombin complex.
[0005] The utility model is achieved through the following technical solutions:
[0006] An auxiliary experimental device for measuring the heparin content in human prothrombin complex, including a vibrator, a test tube rack, and a lighting lamp B. The test tube rack is arranged on the vibrator, and the lighting lamp B is located directly above the test tube rack and is connected to the vibrator through a bracket.
[0007] The vibrator includes a transparent housing, a vibration motor, and a frequency converter. The vibration motor is located inside the transparent housing and is installed on the side wall of the transparent housing. The frequency converter is installed inside the transparent housing and is electrically connected to the vibration motor. The frequency adjustment knob on the frequency converter penetrates through the side wall on one side of the transparent housing and extends outside the transparent housing.
[0008] A lighting lamp A is provided inside the transparent housing.
[0009] A switch is provided on the outer side wall of the transparent housing, and the switch is electrically connected to the lighting lamp A.
[0010] The test tube rack is made of transparent acrylic board.
[0011] The beneficial effects of the present utility model are as follows: The vibrator is used to automatically shake the reaction reagent and the sample to be tested in the test tube, liberating the hands of the experimenter and facilitating the experimenter to observe the solidification situation of the liquid in the test tube; The lighting lamp B is used for supplementary lighting, facilitating the experimenter to quickly and accurately observe the solidification situation of the liquid in the test tube. Description of the Drawings
[0012] Figure 1 It is a schematic structural diagram of the present utility model.
[0013] In the figure: 1 - vibrator, 10 - transparent housing, 11 - switch, 12 - frequency adjustment knob, 2 - test tube rack, 3 - test tube, 4 - support, 5 - lighting lamp B. Detailed Embodiments
[0014] The technical solution of the present utility model will be further described below, but the scope of protection is not limited thereto.
[0015] As Figure 1 shown, an auxiliary experimental device for measuring the heparin content in human prothrombin complex according to the present utility model includes a vibrator 1, a test tube rack 2 and a lighting lamp B5. The test tube rack 2 is installed on the vibrator 1. The lighting lamp B5 is located directly above the test tube rack 2 and is connected to the vibrator 1 through a support 4. During use, a plurality of test tubes 3 are placed on the test tube rack 2, and then reaction reagents and samples to be tested are added to each test tube 3 according to experimental requirements. The vibrator 1 is started to automatically shake the test tube rack 2 and the plurality of test tubes 3 placed on the test tube rack 2 to achieve the purpose of shaking the reaction reagents and samples to be tested in the test tubes 3. Then, the experimenter turns on the lighting lamp B5 and observes the solidification situation of the liquid in the test tubes 3. Using the vibrator 1 to automatically shake the reaction reagents and samples to be tested in the test tubes 3 liberates the hands of the experimenter and facilitates the experimenter to observe the solidification situation of the liquid in the test tubes 3; Supplementary lighting is carried out through the lighting lamp B5, facilitating the experimenter to quickly and accurately observe the solidification situation of the liquid in the test tubes 3.
[0016] The vibrator 1 includes a transparent housing 10, a vibration motor and a frequency converter. The vibration motor is located inside the transparent housing 10 and is installed on the side wall of the transparent housing 10. The frequency converter is installed inside the transparent housing 10 and is electrically connected to the vibration motor. The frequency adjustment knob 12 on the frequency converter penetrates the side wall of one side of the transparent housing 10 and extends outside the transparent housing 10. During use, the frequency of the vibration motor can be adjusted through the frequency adjustment knob 12.
[0017] A lighting lamp A is provided inside the transparent housing 10. Supplementary lighting is carried out from bottom to top by the lighting lamp A, which facilitates the experimenter to quickly and accurately observe the solidification condition of the liquid in the test tube 3.
[0018] A switch 11 is provided on the outer side wall of the transparent housing 10, and the switch 11 is electrically connected to the lighting lamp A.
[0019] The test tube rack 2 is made of transparent acrylic board.
Claims
1. An auxiliary experimental device for determining the heparin content in human prothrombin complex, characterized in that: It comprises a vibrator (1), a test tube rack (2) and an illuminating lamp B (5), wherein the test tube rack (2) is arranged on the vibrator (1), and the illuminating lamp B (5) is located directly above the test tube rack (2) and connected to the vibrator (1) via a bracket (4); The vibrator (1) comprises a transparent housing (10), a vibration motor and a frequency converter, wherein the vibration motor is located in the transparent housing (10) and is mounted on a side wall of the transparent housing (10), the frequency converter is mounted in the transparent housing (10) and is electrically connected to the vibration motor, and the frequency adjustment knob (12) on the frequency converter penetrates the side wall of one side of the transparent housing (10) and extends outside the transparent housing (10); An illumination lamp A is provided inside the transparent housing (10).
2. The auxiliary experimental device for determining the heparin content in human prothrombin complex according to claim 1, characterized in that: A switch (11) is provided on the outer side wall of the transparent housing (10), and the switch (11) is electrically connected to the lighting lamp A.
3. The auxiliary experimental device for determining the heparin content in human prothrombin complex according to claim 1, characterized in that: The test tube rack (2) is made of a transparent acrylic plate.