Novel medicine stability test box

Abstract

The utility model discloses a novel drug stability test box which comprises a tripod and a thermal stability box fixedly installed at the top end of the tripod, a sealing cover is hinged to the position of an opening in the top end of the thermal stability box, and a barrel type middle heat supply unit is arranged in the central axis area in the thermal stability box below the sealing cover. A plurality of column bases used for bearing medicine samples are installed at the bottom of the thermal stabilization box in an annular array mode, an annular base is fixed to the center of the bottom of the thermal stabilization box, and a multidirectional synchronous air blowing structure used for blowing air towards the periphery is installed in the annular base. According to the utility model, heat can uniformly cover each corner in the test box and the surface of a drug sample, so that the temperature of each position is approximately consistent, and the thermal stress difference possibly generated when the drug sample is heated can be obviously reduced due to uniform heating distribution; the stability performance of the medicine under different temperature storage conditions can be accurately evaluated.

Description

Technical Field

[0001] The utility model relates to the technical field of test chambers, and particularly to a new type of drug stability test chamber. Background Art

[0002] A drug stability test chamber (also known as a stability test chamber or a stability chamber) is one of the key devices widely used in the processes of drug research and development, production, and quality control. Its main function is to evaluate and test the stability of drugs under different environmental conditions, ensuring the quality, safety, and effectiveness of drugs during storage and use. Its working principle is based on the precise control and simulation of environmental conditions. During the test, an operator sets the required temperature, humidity, and other conditions, and the control system adjusts the refrigeration, heating, humidity, and lighting systems according to the set values to keep the internal environment of the test chamber stable at the target conditions. The test chamber will run continuously for a period of time to simulate the long-term effects of drugs under different storage conditions;

[0003] For example, a new type of drug sample stability test chamber disclosed in the authorized announcement number CN220542889U includes a box body, a box door is installed on the box body, and a plurality of bearing plates for placing drugs are arranged inside the box body. Through the set limiting mechanism, the bearing plates are detachably installed inside the box body by sliding connection with the guide rails, and through the magnetic connection between the first magnet and the second magnet, the connection stability of the bearing plates is further enhanced. Through the set cleaning driving mechanism, the scraper can be driven to reciprocate on one side of the observation window to realize the scraping operation on the inner side of the observation window, avoiding the fogging on the inner side of the observation window and affecting the observation. However, when conducting a thermal stability experiment on the drug samples inside the box, this technical solution still uses an electric heater for heating. During this process, the drug samples close to the electric heater receive more heat, while the area far from the heater may have a lower temperature. For some drugs, this thermal stress is likely to cause their decomposition or structural changes, thus affecting the accuracy of the stability test results of the drug samples at different positions. Content of the Utility Model

[0004] The purpose of the utility model is to provide a new type of drug stability test chamber. A cylindrical central heating unit is installed in the central axis area inside the thermal stability chamber, and the drug samples to be subjected to the thermal stability experiment are arranged in a ring around the cylindrical central heating unit. At the same time, a stepping motor drives the turbine fan monomers and the multi-directional synchronous air blowing structure to rotate, further forcing the heat to evenly diffuse to each area inside the thermal stability chamber, so as to solve the problems raised in the above background art.

[0005] To achieve the above object, the present utility model provides the following technical solution: a novel drug stability test chamber, comprising a tripod and a thermal stability chamber fixedly installed at the top of the tripod. A sealing cover is hinged at the opening position of the top of the thermal stability chamber. A cylindrical central heating unit is arranged in the central axis area inside the thermal stability chamber below the sealing cover. A plurality of column seats for carrying drug samples are annularly and arrayedly installed at the bottom of the thermal stability chamber. A ring seat is fixed at the central position of the bottom of the thermal stability chamber. A multi-directional synchronous air-blowing structure for blowing air in all directions is installed inside the ring seat. A tapered hollow shaft is rotatably installed inside the ring seat, and a turbine fan unit is fixed inside the tapered hollow shaft. A stepping motor is installed at the bottom of the thermal stability chamber, and the output end of the stepping motor is fixedly connected to the bottom end of the tapered hollow shaft. A PLC control panel is installed on one outer wall of the thermal stability chamber, and the output end of the PLC control panel is electrically connected to the input ends of the stepping motor and the cylindrical central heating unit.

[0006] Preferably, two symmetric exhaust pipes are installed on one outer wall of the thermal stability chamber, and a switching valve is installed at the end of the exhaust pipe far from the thermal stability chamber.

[0007] Preferably, the cylindrical central heating unit includes a partition disk fixed at one end inside the thermal stability chamber, a ventilation pipe fixed at the central position of the bottom end of the partition disk, and an electric heating rod installed inside the ventilation pipe. A plurality of ventilation holes are arranged on the outer peripheral surface of the ventilation pipe, and the inner area of the ventilation pipe is communicated with the inside of the thermal stability chamber through the ventilation holes.

[0008] Preferably, through grooves concentric with the column seats are arranged on the surface of the partition disk.

[0009] Preferably, an annular rib is arranged on the inner edge of the bottom opening of the ventilation pipe, and the lower surface of the annular rib is in rotational fit with the upper surface of the tapered hollow shaft.

[0010] Preferably, the tapered hollow shaft and the ventilation pipe are both made of stainless steel.

[0011] Preferably, the multi-directional synchronous air-blowing structure includes a plurality of equally spaced driven shafts rotatably installed inside the ring seat, bevel gears fixed at one end of the surface of the driven shafts, and fan units installed at the top ends of the driven shafts. The bevel gears are meshed with a bevel gear disk.

[0012] Compared with the prior art, the beneficial effects of the present utility model are as follows: The novel drug stability test chamber is provided with a barrel-type central heating unit, a tapered hollow shaft, a multi-directional synchronous air blowing structure and other cooperating structures, so that the heat generated by the barrel-type central heating unit can be more evenly diffused from the center to the surroundings, effectively reducing the formation of temperature gradients inside the test chamber. Combined with the rotation of the turbine fan unit and the multi-directional synchronous air blowing structure, it can further promote air flow, making the heat more evenly cover every corner inside the test chamber and the surface of the drug samples, thus ensuring that the temperatures at various positions are close to the same. The uniform heating distribution can significantly reduce the thermal stress differences that may occur when the drug samples are heated, helping to accurately evaluate the stability performance of the drugs under different temperature storage conditions and providing a more reliable temperature control environment for the staff. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 is a schematic three-dimensional structure of the present utility model Figure 1 ;

[0014] Figure 2 is a schematic three-dimensional structure of the present utility model Figure 2 ;

[0015] Figure 3 is a schematic front view structure of the present utility model Figure 3 ;

[0016] Figure 4 is a schematic three-dimensional sectional structure of the present utility model Figure 1 ;

[0017] Figure 5 is a schematic three-dimensional sectional structure of the present utility model Figure 2 .

[0018] In the figures: 1, tripod; 2, thermal stability box; 201, column base; 3, sealing cover; 4, exhaust pipe; 5, partition plate; 501, through groove; 6, barrel-type central heating unit; 601, ventilation pipe; 602, electric heating rod; 7, PLC control panel; 8, ring base; 9, multi-directional synchronous air blowing structure; 901, driven shaft; 902, bevel gear; 903, fan unit; 10, tapered hollow shaft; 11, bevel gear disc; 12, stepping motor; 13, turbine fan unit. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0019] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Based on the embodiments in the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present utility model.

[0020] Please refer toFigures 1-5 , an embodiment provided by the present utility model: a new type of drug stability test chamber, including a tripod 1 and a thermal stability chamber 2 fixedly installed at the top of the tripod 1. A sealing cover 3 is hinged at the opening position at the top of the thermal stability chamber 2. A cylindrical central heating unit 6 is arranged in the central axis area inside the thermal stability chamber 2 below the sealing cover 3. A plurality of column seats 201 for carrying drug samples are annularly and arrayedly installed at the bottom of the thermal stability chamber 2. A ring seat 8 is fixed at the central position of the bottom of the thermal stability chamber 2. A multi-directional synchronous air blowing structure 9 for blowing air around is installed inside the ring seat 8. A tapered hollow shaft 10 is rotatably installed inside the ring seat 8. A turbine fan unit 13 is fixed inside the tapered hollow shaft 10. A stepping motor 12 is installed at the bottom of the thermal stability chamber 2. The output end of the stepping motor 12 is fixedly connected to the bottom end of the tapered hollow shaft 10. A PLC control panel 7 is installed on the outer wall of one side of the thermal stability chamber 2. The output end of the PLC control panel 7 is electrically connected to the input ends of the stepping motor 12 and the cylindrical central heating unit 6;

[0021] Two symmetric exhaust pipes 4 are installed on the outer wall of one side of the thermal stability chamber 2. A switch valve (not shown) is installed at the end of the exhaust pipe 4 away from the thermal stability chamber 2;

[0022] The cylindrical central heating unit 6 includes a partition disk 5 fixed at one end inside the thermal stability chamber 2, a ventilation pipe 601 fixed at the center position at the bottom end of the partition disk 5, and an electric heating rod 602 installed inside the ventilation pipe 601. Through grooves 501 concentric with the column seats 201 are arranged on the surface of the partition disk 5. After the sealing cover 3 is turned over and opened, the staff can place the drug samples into the column seats 201 through the through grooves 501, so that the drug samples are distributed around the cylindrical central heating unit 6;

[0023] A plurality of ventilation holes are arranged on the outer peripheral surface of the ventilation pipe 601. The internal area of the ventilation pipe 601 is communicated with the inside of the thermal stability chamber 2 through the ventilation holes. The staff turns on the electric heating rod 602 to work through the PLC control panel 7. The electric heating rod 602 is located in the central axis area of the thermal stability chamber 2 and serves as the main heating source. Its structural design can make the heat radiate from the center to the surroundings, achieving a more uniform heating effect. And the plurality of through holes on the surface of the ventilation pipe 601 enable the heat to be evenly dissipated, reducing the temperature gradient problem that may be caused by uneven heating;

[0024] Both the tapered hollow shaft 10 and the ventilation pipe 601 are made of stainless steel. An annular rib is arranged on the inner edge of the bottom opening of the ventilation pipe 601. The lower surface of the annular rib is rotatably matched with the upper surface of the tapered hollow shaft 10, and the rotational stability of the tapered hollow shaft 10 is improved through the annular rib;

[0025] The stepping motor 12 drives the tapered hollow shaft 10, the bevel gear disc 11, and the turbine fan unit 13 to rotate. The turbine fan unit 13 blows air upward to promote the rapid dissipation of heat from the ventilation pipe 601. During this process, the stepping motor 12 can precisely control the rotation speed of the turbine fan unit 13, thereby adjusting the direction and intensity of air flow;

[0026] The multi-directional synchronous air blowing structure 9 includes a plurality of equally spaced driven shafts 901 rotatably installed inside the ring seat 8, bevel gears 902 fixed to one end of the surface of the driven shafts 901, and fan units 903 installed at the top ends of the driven shafts 901. The bevel gears 902 are meshed with the bevel gear disc 11. The number of driven shafts 901 can be set to four. When the bevel gear disc 11 rotates together with the tapered hollow shaft 10, the bevel gear disc 11 will drive the driven shafts 901 and the fan units 903 to rotate through the bevel gears 902. It can adjust the air blowing and guiding in different directions to further enhance the uniformity and coverage of air flow, ensuring that heat can be evenly transferred to the surface of each drug sample to be tested.

[0027] When the embodiment of the present application is in use, first, the staff opens the sealing cover 3 and places the drug samples to be subjected to the thermal stability test in each column seat 201 at the bottom of the thermal stability chamber 2. At this time, each drug sample is arranged in an annular and equally spaced form around the circumferential side of the cylindrical central heating unit 6. After the drug samples are arranged, the staff closes the sealing cover 3 and starts the cylindrical central heating unit 6 and the stepping motor 12 to work through the PLC control panel 7. The PLC control panel 7 will start the cylindrical central heating unit 6 and the stepping motor 12 according to the preset temperature curve. Then, the rotational power of the stepping motor 12 is transmitted to the tapered hollow shaft 10 and the turbine fan unit 13. At the same time, the tapered hollow shaft 10 drives the multi-directional synchronous air blowing structure 9 to work through the bevel gear disc 11. The design of the tapered hollow shaft 10 ensures the stable operation of the turbine fan unit 13 and the effective guiding of air flow. The cylindrical central heating unit 6 continuously radiates heat energy into the thermal stability chamber 2, while the turbine fan unit 13 and the multi-directional synchronous air blowing structure 9 continuously promote air flow. The stepping motor 12 precisely adjusts the rotation speed and direction of the turbine fan unit 13 through the instructions of the PLC control panel 7 to ensure that the heat in the air can evenly cover each drug sample in the test chamber, continuously keeping the internal environment of the test chamber stable under the target conditions. The thermal stability chamber 2 operates continuously for a period of time to simulate the long-term effects of the drug under this temperature condition. After the thermal stability test is completed, the staff takes out the drugs in the thermal stability chamber 2 and conducts further tests.

Claims

1. A new type of drug stability test chamber, characterized in that: It includes a tripod (1) and a thermal stability box (2) fixedly installed at the top of the tripod (1). At the opening position at the top of the thermal stability box (2), a sealing cover (3) is hinged. In the central axis area inside the thermal stability box (2) below the sealing cover (3), a cylindrical central heating unit (6) is provided. At the bottom of the thermal stability box (2), a number of column bases (201) for carrying medicine samples are installed in an annular array. At the central position of the bottom of the thermal stability box (2), a ring base (8) is fixed. Inside the ring base (8), a multi-directional synchronous air blowing structure (9) for blowing air all around is installed. Inside the ring base (8), a tapered hollow shaft (10) is rotatably installed. Inside the tapered hollow shaft (10), a turbine fan unit (13) is fixed. At the bottom of the thermal stability box (2), a stepping motor (12) is installed. The output end of the stepping motor (12) is fixedly connected to the bottom end of the tapered hollow shaft (10). On one outer wall of the thermal stability box (2), a PLC control panel (7) is installed. The output end of the PLC control panel (7) is electrically connected to the input ends of the stepping motor (12) and the cylindrical central heating unit (6).

2. A novel drug stability test chamber according to claim 1, characterized in that: On one outer wall of the thermal stability box (2), two symmetrical exhaust pipes (4) are installed. At the end of the exhaust pipe (4) away from the thermal stability box (2), a switch valve is installed.

3. A novel drug stability test chamber according to claim 1, characterized in that: The cylindrical central heating unit (6) includes a partition disk (5) fixed at one end inside the thermal stability box (2), a ventilation pipe (601) fixed at the central position of the bottom end of the partition disk (5), and an electric heating rod (602) installed inside the ventilation pipe (601). A number of ventilation holes are provided on the outer peripheral surface of the ventilation pipe (601). The internal area of the ventilation pipe (601) is interconnected with the inside of the thermal stability box (2) through the ventilation holes.

4. A novel drug stability test chamber according to claim 3, characterized in that: On the surface of the partition disk (5), a through groove (501) concentric with the column base (201) is provided.

5. A novel drug stability test chamber according to claim 3, characterized in that: On the inner edge of the bottom opening of the ventilation pipe (601), an annular rib is provided. The lower surface of the annular rib is rotationally matched with the upper surface of the tapered hollow shaft (10).

6. A novel drug stability test chamber according to claim 3, characterized in that: Both the tapered hollow shaft (10) and the ventilation pipe (601) are made of stainless steel.

7. A novel drug stability test chamber according to claim 1, characterized in that: The multi-directional synchronous air blowing structure (9) includes a number of equally spaced driven shafts (901) rotatably installed inside the ring base (8), bevel gears (902) fixed at one end of the surface of the driven shafts (901), and fan units (903) installed at the top ends of the driven shafts (901). The bevel gears (902) are meshed with a bevel gear disk (11).

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