Elastic biological material freeze-drying mold

By designing a freeze-drying mold including the first template, the limiting ring, the second template, the threaded rod and the pressing plate, the problem of uneven finished products during the lyophilization of elastic biological materials is solved, and the effect of rapid freeze-drying and product flatness is achieved.

CN223077277UActive Publication Date: 2025-07-08广州领衔生物科技有限公司
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Patent Information

Application Number
CN202421900114.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-07
Publication Date
2025-07-08
Estimated Expiration
2034-08-07

AI Technical Summary

Technical Problem

During the lyophilization process, elastic biomaterials such as the pericardial and submucosal tissue of the small intestine are uneven, causing wrinkles, unevenness or too thickness in the finished product after lyophilization, which affects product performance and use. Flattening with a press plate will affect the sublimation of the biocollagen membrane and water vapor escape.

Method used

An elastic biomaterial freeze-dried mold including a first template, a limiting ring, a second template, a threaded rod and a pressure plate is designed to increase the contact area between the material and the air by the arrangement of the grooves and through holes, and to achieve a flat fixation of the material by the coordination of the threaded rod and the pressure plate.

Benefits of technology

By increasing the contact area between the material and the air and smoothing treatment, the lyophilization speed is improved, ensuring that the product is smooth and wrinkle-free after lyophilization, and improving product performance and usage effect.

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Abstract

The utility model discloses an elastic biological material freeze-drying mold which comprises a first mold plate, a groove is formed in the top of the first mold plate, and a limiting ring is fixedly connected to the top of the first mold plate. According to the elastic biological material freeze-drying device, an operator puts an elastic biological material to be freeze-dried on the top of the first template, then slides the second template into the through hole from back to front until the second template is attached to the positioning block, and then loosens the second template, the second template moves downwards to press the top of the elastic biological material to be freeze-dried, and the elastic biological material is freeze-dried. Then an operator rotates a rotating handle to drive a threaded rod to rotate, then the threaded rod and a pressing disc are driven to move downwards, then a second template is properly pressed downwards, then the to-be-freeze-dried elastic biological material is fixed through a fixing needle, and through the arrangement of a through hole and a groove, the contact area between the to-be-freeze-dried elastic biological material and air can be increased; therefore, the freeze-drying speed of the to-be-freeze-dried elastic biological material is increased, and the device has the advantage of being convenient to use.
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Description

Technical Field

[0001] The utility model relates to the technical field of freeze-drying molds, in particular to a freeze-drying mold for elastic biological materials. Background Technique

[0002] "Freeze-drying" utilizes the three-state change of water. Under high vacuum, based on the sublimation principle, the water in the pre-frozen material is directly sublimated into water vapor without passing through the melting of ice, so as to achieve freeze-drying.

[0003] When freeze-drying elastic biological materials such as bovine pericardium and small intestinal submucosa tissue, if these tissues are uneven before being put into the freeze-dryer, the freeze-dried products will have wrinkles, unevenness, or even excessive thickness, which will affect the performance and use of the products; if a pressing plate is used to flatten the elastic biological materials during the freeze-drying process, it will affect the sublimation of the biological collagen membrane and the escape of the water vapor released by desorption, thus affecting the freeze-drying effect of the biological collagen membrane. Therefore, it is necessary to design and transform the freeze-drying mold for elastic biological materials to effectively prevent the phenomenon of inconvenient use. Summary of the Utility Model

[0004] To solve the problems raised in the above background technique, the purpose of the present utility model is to provide a freeze-drying mold for elastic biological materials, which has the advantage of being easy to use, and solves the problems that when freeze-drying elastic biological materials such as bovine pericardium and small intestinal submucosa tissue, if these tissues are uneven before being put into the freeze-dryer, the freeze-dried products will have wrinkles, unevenness, or even excessive thickness, which will affect the performance and use of the products; if a pressing plate is used to flatten the elastic biological materials during the freeze-drying process, it will affect the sublimation of the biological collagen membrane and the escape of the water vapor released by desorption, thus affecting the freeze-drying effect of the biological collagen membrane.

[0005] To achieve the above purpose, the present utility model provides the following technical solution: A freeze-drying mold for elastic biological materials, including a first template, a groove is provided on the top of the first template, a limiting ring is fixedly connected to the top of the first template, through openings are provided on the front and back of the limiting ring, a second template is movably connected inside the limiting ring, through holes are provided on the surface of the second template, the second template is movably connected to the first template, support frames are fixedly connected to both sides of the top of the limiting ring, threaded rods are threadedly connected inside the support frames, a pressing plate is fixedly connected to the bottom of the threaded rods, and the pressing plate is movably connected to the second template.

[0006] Preferably, a turning handle is fixedly connected to the top of the threaded rod, and an anti-slip sleeve is provided on the surface of the turning handle, and the anti-slip sleeve is made of silica gel material.

[0007] Preferably, a positioning block is fixedly connected to the inner wall of the through port, and the positioning block is movably connected to the second template.

[0008] Preferably, a fixing needle is movably connected inside the through hole. The top of the fixing needle is fixedly connected to a holding rod, and anti-slip grooves are provided on the surface of the holding rod.

[0009] Preferably, handles are fixedly connected to both sides of the top of the second template. Anti-slip patterns are provided on the surface of the handles. The number of anti-slip patterns is several, and the anti-slip patterns are evenly distributed on the surface of the handles.

[0010] Preferably, the number of the grooves is several, and the number of the through holes is several. The grooves are evenly distributed on the top of the first template, and the through holes are evenly distributed on the top of the second template. The inner diameter of the through holes is smaller than the inner diameter of the grooves.

[0011] Compared with the prior art, the beneficial effects of the present utility model are as follows:

[0012] 1. In the present utility model, the operator places the elastic biological material to be freeze-dried on the top of the first template, then slides the second template into the through port from back to front until the second template fits with the positioning block, and then releases the second template. The second template moves downward and presses on the top of the elastic biological material to be freeze-dried. Then the operator rotates the rotating handle to drive the threaded rod to rotate, thereby driving the threaded rod and the pressing plate to move downward, and further appropriately pressing down the second template. Then, the fixing needle is used to fix the elastic biological material to be freeze-dried. Through the settings of the through holes and the grooves, the contact area between the elastic biological material to be freeze-dried and the air can be increased, thereby accelerating the freeze-drying speed of the elastic biological material to be freeze-dried. This device has the advantage of being easy to use.

[0013] 2. Through the setting of the rotating handle in the present utility model, the operator can utilize the principle of the labor-saving lever, thereby facilitating the operator to easily rotate the threaded rod. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 is a schematic structural diagram of the present utility model;

[0015] Figure 2 is a schematic structural diagram of the first template of the present utility model;

[0016] Figure 3 is a schematic structural diagram of the fixing needle of the present utility model;

[0017] Figure 4 is the present utility model Figure 2 The enlarged schematic diagram of the structure at A in.

[0018] In the figure: 1. First template; 2. Groove; 3. Limit ring; 4. Through port; 5. Second template; 6. Through hole; 7. Support frame; 8. Threaded rod; 9. Pressing disc; 10. Rotating handle; 11. Fixed needle; 12. Holding rod; 13. Anti-slip groove; 14. Handle; 15. Positioning block. Detailed implementation manners

[0019] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0020] As Figures 1 to 4 shown, an elastic biomaterial freeze-drying mold includes a first template 1. A groove 2 is provided at the top of the first template 1. A limit ring 3 is fixedly connected to the top of the first template 1. Through ports 4 are provided on the front and back surfaces of the limit ring 3. A second template 5 is movably connected inside the limit ring 3. Through holes 6 are provided on the surface of the second template 5. The second template 5 is movably connected to the first template 1. Support frames 7 are fixedly connected to both sides of the top of the limit ring 3. A threaded rod 8 is threadedly connected inside the support frames 7. A pressing disc 9 is fixedly connected to the bottom of the threaded rod 8. The pressing disc 9 is movably connected to the second template 5.

[0021] Referring to Figure 1 、 Figure 2 and Figure 4 , a rotating handle 10 is fixedly connected to the top of the threaded rod 8. An anti-slip sleeve is provided on the surface of the rotating handle 10, and the anti-slip sleeve is made of silicone material.

[0022] As a technical optimization scheme of the present invention, through the setting of the rotating handle 10, the operator can utilize the principle of the labor-saving lever, thereby facilitating the operator to easily rotate the threaded rod 8.

[0023] Referring to Figure 1 and Figure 2 , a positioning block 15 is fixedly connected to the inner wall of the through port 4. The positioning block 15 is movably connected to the second template 5.

[0024] As a technical optimization scheme of the present invention, through the setting of the positioning block 15, the operator slides the second template 5 from back to front until the second template 5 fits with the positioning block 15. At this time, the second template 5 moves to the preset position.

[0025] Referring to Figure 1 and Figure 3, a fixing pin 11 is movably connected inside the through hole 6. A holding rod 12 is fixedly connected to the top of the fixing pin 11, and anti-slip grooves 13 are arranged on the surface of the holding rod 12.

[0026] As a technical optimization scheme of the present utility model, through the arrangement of the fixing pin 11, the holding rod 12 and the anti-slip grooves 13, the operator can hold the holding rod 12, penetrate the bottom of the fixing pin 11 through the through hole 6, and then insert it into the elastic biological material, thereby fixing the elastic biological material, avoiding the finished product of the freeze-dried elastic biological material being flat without wrinkles and preventing local over-thickness from affecting the product performance and use.

[0027] Reference Figure 1 , handles 14 are fixedly connected to both sides of the top of the second template 5. Anti-slip lines are arranged on the surface of the handles 14, and the number of the anti-slip lines is several, and the anti-slip lines are evenly distributed on the surface of the handles 14.

[0028] As a technical optimization scheme of the present utility model, through the arrangement of the handles 14, it is convenient for the operator to move the second template 5 back and forth.

[0029] Reference Figure 1 , Figure 2 and Figure 4 , the number of the grooves 2 is several, and the number of the through holes 6 is several. The grooves 2 are evenly distributed on the top of the first template 1, and the through holes 6 are evenly distributed on the top of the second template 5. The inner diameter of the through hole 6 is smaller than the inner diameter of the groove 2.

[0030] As a technical optimization scheme of the present utility model, by having several grooves 2 and through holes 6, the contact area between the elastic biological material to be freeze-dried and the air is increased, thereby accelerating the drying of the elastic biological material to be freeze-dried.

[0031] The working principle and usage process of the present utility model: During use, the operator places the elastic biological material to be freeze-dried on the top of the first template 1, then slides the second template 5 into the through port 4 from back to front until the second template 5 fits against the positioning block 15, then releases the second template 5, and the second template 5 moves downward and presses on the top of the elastic biological material to be freeze-dried. Then the operator rotates the rotating handle 10 to drive the threaded rod 8 to rotate, thereby driving the threaded rod 8 and the pressing plate 9 to move downward, thereby appropriately pressing down the second template 5. Then use the fixing pin 11 to fix the elastic biological material to be freeze-dried. Through the arrangement of the through holes 6 and the grooves 2, the contact area between the elastic biological material to be freeze-dried and the air can be increased, thereby accelerating the freeze-drying speed of the elastic biological material to be freeze-dried.

[0032] It should be noted that in this text, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprising", "including" or any other variant thereof are intended to cover non-exclusive inclusion, such that a process, method, article or device comprising a series of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article or device.

[0033] Although embodiments of the present invention have been shown and described, those of ordinary skill in the art can understand that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An elastic biomaterial freeze-drying mold, comprising a first template (1), characterized in that: A groove (2) is provided at the top of the first template (1). A limit ring (3) is fixedly connected to the top of the first template (1). Through openings (4) are provided on both the front and back surfaces of the limit ring (3). A second template (5) is movably connected inside the limit ring (3). Through holes (6) are provided on the surface of the second template (5). The second template (5) is movably connected to the first template (1). Support frames (7) are fixedly connected to both sides of the top of the limit ring (3). A threaded rod (8) is threadedly connected inside the support frame (7). A pressing plate (9) is fixedly connected to the bottom of the threaded rod (8). The pressing plate (9) is movably connected to the second template (5).

2. The elastic biomaterial freeze-drying mold according to claim 1, wherein: A rotating handle (10) is fixedly connected to the top of the threaded rod (8). An anti-slip sleeve is provided on the surface of the rotating handle (10), and the anti-slip sleeve is made of silica gel material.

3. The elastic biomaterial freeze-drying mold according to claim 1, wherein: A positioning block (15) is fixedly connected to the inner wall of the through opening (4). The positioning block (15) is movably connected to the second template (5).

4. The lyophilization mold of an elastic biomaterial according to claim 1, characterized in that: A fixing needle (11) is movably connected inside the through hole (6). A holding rod (12) is fixedly connected to the top of the fixing needle (11). Anti-slip grooves (13) are provided on the surface of the holding rod (12).

5. The elastic biomaterial freeze-drying mold according to claim 1, wherein: Handles (14) are fixedly connected to both sides of the top of the second template (5). Anti-slip patterns are provided on the surface of the handles (14), and the number of anti-slip patterns is several, and the anti-slip patterns are evenly distributed on the surface of the handles (14).

6. The lyophilization mold of an elastic biomaterial according to claim 1, wherein: The number of the grooves (2) is several. The number of the through holes (6) is several. The grooves (2) are evenly distributed on the top of the first template (1). The through holes (6) are evenly distributed on the top of the second template (5). The inner diameter of the through holes (6) is smaller than the inner diameter of the grooves (2).