High-pressure homogenizer for microsphere preparation

Abstract

The utility model belongs to the field of microsphere preparation, and particularly relates to a high-pressure homogenizer for microsphere preparation, which comprises a homogenizer body, the homogenizer body comprises a main body, a feeding pipe is arranged at the bottom of the right side of the main body, the top of the feeding pipe is communicated with a feeding funnel, a flow guide mechanism is arranged in an inner cavity of the feeding funnel, and the flow guide mechanism is communicated with the main body. Fixing mechanisms are arranged on the two sides of the feeding hopper; the threaded column is in threaded connection with the inner cavity of the cylindrical block, then the lapping rod is placed on the top of the feeding hopper, meanwhile, the tension spring, the clamping groove, the clamping block and the positioning rod are arranged, the elliptic column is pulled manually, the tension spring can extend downwards, the clamping groove is connected to the surface of the positioning rod in a clamped mode after the elliptic column is pulled to a proper position, and the feeding hopper is clamped. Therefore, the fluid drainage effect is achieved, and the problem that the feeding speed of the machine is low due to the fact that the difference between the diameter of the feeding hopper and the diameter of the feeding port is too large when the fluid passes through the feeding port, and the microsphere preparation speed is low is solved.

Description

Technical Field

[0001] The utility model relates to the field of microsphere preparation, and specifically relates to a high-pressure homogenizer for microsphere preparation. Background Art

[0002] A high-pressure homogenizer, also known as a "high-pressure fluid nano-homogenizer", can make the material in a suspension state flow at high speed through a cavity with a special internal structure (high-pressure homogenization cavity) under the action of ultra-high pressure, causing a series of changes in the physical, chemical, and structural properties of the material, and finally achieving the effect of homogenization.

[0003] The high-pressure homogenizer is widely used in the field of microsphere preparation. However, when homogenizing the fluid, the fluid passing through the feed port will have a large difference between the diameter of the feed hopper and the diameter of the feed port, which will lead to slow fluid feeding speed, easy accumulation, and large-area adhesion to the inner wall of the feed hopper, resulting in difficult subsequent cleaning. Content of the Utility Model

[0004] In order to make up for the deficiencies of the prior art, due to the large difference between the diameter of the feed hopper and the diameter of the feed port, which will lead to slow fluid feeding speed, easy accumulation, and large-area adhesion to the inner wall of the feed hopper, resulting in difficult subsequent cleaning, the utility model proposes a high-pressure homogenizer for microsphere preparation.

[0005] The technical solution adopted by the utility model to solve its technical problems is: a high-pressure homogenizer for microsphere preparation, including a homogenizer body, the homogenizer body includes a main body, a feed pipe is arranged at the bottom on the right side of the main body, a feed hopper is connected to the top of the feed pipe, a flow guiding mechanism is arranged in the inner cavity of the feed hopper, and fixing mechanisms are arranged on both sides of the feed hopper;

[0006] The flow guiding mechanism includes a column rod, a vortex extension plate is fixedly connected to the surface of the column rod, the vortex extension plate is spiral and the surface of the vortex extension plate is movably connected to the inner wall of the feed hopper, an outer limit block is fixedly connected to one side of the top of the vortex extension plate, an inner limit block is fixedly connected to the other side of the top of the vortex extension plate, the inner limit block is located inside the inner circle of the vortex extension plate, and the outer limit block is located outside the outer circle of the vortex extension plate.

[0007] Preferably, a threaded column is fixedly connected to the top of the column rod, and a cylindrical block is threadedly connected to the top of the threaded column.

[0008] Preferably, a connecting rod is fixedly connected to the top of the cylindrical block, handles are fixedly connected to both sides of the top of the connecting rod, and square columns are fixedly connected to both sides of the bottom of the connecting rod.

[0009] Preferably, the fixing mechanism includes a connecting block, the surface of the connecting block is fixedly connected to one side of the square column, a limiting groove is formed inside the connecting block, a rotating shaft is fixedly connected to the inner wall of the limiting groove, the rotating shaft penetrates to both sides of the limiting groove, and a movable block is rotatably connected to the surface of the rotating shaft.

[0010] Preferably, a circular fixing block is fixedly connected to the bottom of the movable block, and a tension spring is fixedly connected to the bottom of the circular fixing block.

[0011] Preferably, a clamping block is fixedly connected to the bottom of the tension spring, and elliptical cylinders are fixedly connected to both sides of the surface of the clamping block.

[0012] Preferably, a clamping groove is formed inside the clamping block, a positioning rod is movably connected to the inner cavity of the clamping groove, and the positioning rod is fixedly connected to the surface of the feeding funnel.

[0013] The beneficial effects of the present utility model are as follows:

[0014] In the present utility model, the threaded column is threadedly connected to the inner cavity of the cylindrical block, and then the cross bar is placed on the top of the feeding funnel. At the same time, by setting the tension spring, the clamping groove, the clamping block and the positioning rod, the elliptical cylinder is pulled manually, the tension spring will extend downward, and after being stretched to an appropriate position, the clamping groove is clamped to the surface of the positioning rod, so as to achieve the effect of fluid drainage, and solve the problem that the fluid passing through the feeding port will have a large difference between the diameter of the feeding hopper and the diameter of the feeding port, resulting in a slow feeding speed of the machine, and thus solve the problem of low microsphere preparation speed. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] In order to more clearly illustrate the technical solutions in the embodiments of the present utility model or the prior art, the following will briefly introduce the drawings required for the description of the embodiments or the prior art. Obviously, the following drawings are only some embodiments of the present utility model. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.

[0016] Figure 1 It is a three-dimensional structural schematic diagram of the present utility model;

[0017] Figure 2 It is a structural schematic diagram of the feeding funnel and the vortex extension plate of the present utility model;

[0018] Figure 3 It is a structural schematic diagram of the cross bar and the column rod of the present utility model;

[0019] Figure 4 It is a structural schematic diagram of the connection between the column rod and the cross bar of the present utility model;

[0020] Figure 5This is a schematic structural diagram of the card slot and positioning rod of the present utility model.

[0021] In the figure: 1, homogenizer body; 101, main body; 102, feed pipe; 103, feed hopper; 2, diversion mechanism; 201, column rod; 202, vortex extension plate; 203, outer limit block; 204, inner limit block; 205, threaded column; 206, cylindrical block; 3, fixing mechanism; 301, connecting block; 302, limit groove; 303, rotating shaft; 304, circular fixing block; 305, tension spring; 306, clamping block; 307, elliptical cylinder; 308, card slot; 309, positioning rod; 310, movable block; 4, square column; 5, connecting rod; 6, handle. Detailed implementation manners

[0022] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present utility model.

[0023] The following is a further detailed description of this application Figures 1-5 in conjunction with the attached drawings.

[0024] The embodiment of this application discloses a high-pressure homogenizer for microsphere preparation. Referring to Figure 1 and Figure 3 , a high-pressure homogenizer for microsphere preparation includes a homogenizer body 1. The homogenizer body 1 includes a main body 101. A feed pipe 102 is arranged at the bottom on the right side of the main body 101. The top of the feed pipe 102 is communicated with a feed hopper 103. A diversion mechanism 2 is arranged in the inner cavity of the feed hopper 103. Fixing mechanisms 3 are arranged on both sides of the feed hopper 103;

[0025] The diversion mechanism 2 includes a column rod 201. A vortex extension plate 202 is fixedly connected to the surface of the column rod 201. The vortex extension plate 202 is spiral-shaped and the surface of the vortex extension plate 202 is movably connected to the inner wall of the feed hopper 103. One side of the top of the vortex extension plate 202 is fixedly connected with an outer limit block 203, and the other side of the top of the vortex extension plate 202 is fixedly connected with an inner limit block 204. The inner limit block 204 is located at the inner circle of the vortex extension plate 202, and the outer limit block 203 is located at the outer circle of the vortex extension plate 202. Through the combined use of the outer limit block 203, the inner limit block 204 and the vortex extension plate 202, and the vortex extension plate 202 has a diversion effect. At the same time, the outer limit block 203 and the inner limit block 204 are respectively arranged at the outer circle and the inner circle of the top of the vortex extension plate 202, which realizes the blocking of the fluid and the limiting of the fluid, and improves the feeding speed;

[0026] Refer to Figure 3 and Figure 4 As shown in the figure, a threaded column 205 is fixedly connected to the top of the column rod 201, and a cylindrical block 206 is threadedly connected to the top of the threaded column 205. By the combined use of the threaded column 205 and the cylindrical block 206, and the cylindrical block 206 and the threaded column 205 are in threaded connection, the disassembly and installation between the column rod 201 and the cylindrical block 206 are realized;

[0027] Refer to Figure 4 As shown in the figure, a connecting rod 5 is fixedly connected to the top of the cylindrical block 206, and handles 6 are fixedly connected to both sides of the top of the connecting rod 5. Square columns 4 are fixedly connected to both sides of the bottom of the connecting rod 5. By the combined use of the connecting rod 5 and the handles 6, and the handles 6 are arranged above the connecting rod 5, the effect of being able to disassemble the flow guiding mechanism 2 and the fixing mechanism 3 by hand is realized;

[0028] Refer to Figure 5 As shown in the figure, the fixing mechanism 3 includes a connecting block 301. The surface of the connecting block 301 is fixedly connected to one side of the square column 4. A limiting groove 302 is opened inside the connecting block 301. A rotating shaft 303 is fixedly connected to the inner wall of the limiting groove 302. The rotating shaft 303 penetrates to both sides of the limiting groove 302. An active block 310 is rotatably connected to the surface of the rotating shaft 303. Through the setting of the limiting groove 302, it is convenient to install the rotating shaft 303 inside the connecting block 301. At the same time, through the setting of the rotating shaft 303, the position of the active block 310 is supported, and the connecting block 301 can be rotated at a large angle;

[0029] Refer to Figure 5 As shown in the figure, a circular fixing block 304 is fixedly connected to the bottom of the active block 310, and a tension spring 305 is fixedly connected to the bottom of the circular fixing block 304. By arranging the tension spring 305 below the circular fixing block 304 and using the two in combination, the position of the tension spring 305 can be effectively limited. Through the setting of the circular fixing block 304, the tension spring 305 and the active block 310 are stably fixed;

[0030] Refer to Figure 5 As shown in the figure, a clamping block 306 is fixedly connected to the bottom of the tension spring 305. Elliptical columns 307 are fixedly connected to both sides of the surface of the clamping block 306. By fixing both sides of the clamping block 306 with the elliptical columns 307, it is more convenient for the human hand to support on the elliptical columns 307. When the clamping block 306 needs to be removed, it can be pulled down by hand, and the purpose of easy disassembly is realized;

[0031] Refer to Figure 5, a clamping groove 308 is formed in the inner cavity of the clamping block 306, and a positioning rod 309 is movably connected in the inner cavity of the clamping groove 308. The positioning rod 309 is fixedly connected to the surface of the feeding funnel 103. By the cooperation of the clamping groove 308 and the positioning rod 309, the clamping block 306, the square column 4 and the bracing rod 5 can be effectively fixed, and the clamping groove 308 and the positioning rod 309 can be more stably clamped;

[0032] Working principle: First, thread the cylindrical block 206 fixed under the bracing rod 5 onto the threaded column 205. Then, place the bracing rod 5 above the feeding funnel 103. Then, hold the ellipsoidal column 307 by hand and press it downwards. During the pressing process, the force will be transmitted to the tension spring 305, and the tension spring 305 will be stretched downwards and deformed. When it is pulled down to the appropriate position, the clamping block 306 will drive the clamping groove 308 to be sleeved on the surface of the positioning rod 309 to achieve clamping. After the fixation is completed, the feeding funnel 103 can be filled with fluid. When the fluid is poured onto the vortex extension plate 202, and the vortex extension plate 202 is in a vortex shape, the fluid will move in a vortex and slide down along the vortex extension plate 202. In this way, the travel distance of the fluid can be increased and conveyed to the feeding port. Here, the outer limiting block 203 and the inner limiting block 204 are arranged at the top of the vortex extension plate 202 to limit and block the fluid, so that the fluid can smoothly flow down along the surface of the vortex extension plate 202, thereby improving the fluid feeding speed.

[0033] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited by the above embodiments. What is described in the above embodiments and the specification only illustrates the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention will have various changes and improvements, and these changes and improvements all fall within the scope of the present invention claimed.

Claims

1. A high-pressure homogenizer for microsphere preparation, characterized in that: It includes a homogenizer body (1). The homogenizer body (1) includes a main body (101). At the bottom on the right side of the main body (101), there is a feed pipe (102). At the top of the feed pipe (102), there is a feed hopper (103) connected. Inside the cavity of the feed hopper (103), there is a diversion mechanism (2). On both sides of the feed hopper (103), there are fixing mechanisms (3). The diversion mechanism (2) includes a column rod (201). On the surface of the column rod (201), there is a spiral extension plate (202) fixedly connected. The spiral extension plate (202) is spiral-shaped and the surface of the spiral extension plate (202) is movably connected to the inner wall of the feed hopper (103). On one side at the top of the spiral extension plate (202), there is an outer limit block (203) fixedly connected. On the other side at the top of the spiral extension plate (202), there is an inner limit block (204) fixedly connected. The inner limit block (204) is located at the inner circle of the spiral extension plate (202), and the outer limit block (203) is located at the outer circle of the spiral extension plate (202).

2. The high-pressure homogenizer for preparing microspheres according to claim 1, characterized in that: At the top of the column rod (201), there is a threaded column (205) fixedly connected. At the top of the threaded column (205), there is a cylindrical block (206) threadedly connected.

3. The high-pressure homogenizer for preparing microspheres according to claim 2, wherein: At the top of the cylindrical block (206), there is a connecting rod (5) fixedly connected. On both sides at the top of the connecting rod (5), there are handles (6) fixedly connected. On both sides at the bottom of the connecting rod (5), there are square columns (4) fixedly connected.

4. A high-pressure homogenizer for preparing microspheres according to claim 3, characterized in that: The fixing mechanism (3) includes a connecting block (301). The surface of the connecting block (301) is fixedly connected to one side of the square column (4). Inside the connecting block (301), there is a limit slot (302). On the inner wall of the limit slot (302), there is a rotating shaft (303) fixedly connected. The rotating shaft (303) penetrates to both sides of the limit slot (302). On the surface of the rotating shaft (303), there is a movable block (310) rotatably connected.

5. The high-pressure homogenizer for preparing microspheres according to claim 4, wherein: At the bottom of the movable block (310), there is a circular fixing block (304) fixedly connected. At the bottom of the circular fixing block (304), there is a tension spring (305) fixedly connected.

6. The high-pressure homogenizer for preparing microspheres according to claim 5, wherein: At the bottom of the tension spring (305), there is a clamping block (306) fixedly connected. On both sides of the surface of the clamping block (306), there are elliptical columns (307) fixedly connected.

7. A high-pressure homogenizer for preparing microspheres according to claim 6, characterized in that: Inside the clamping block (306), there is a clamping slot (308). Inside the clamping slot (308), there is a positioning rod (309) movably connected. The positioning rod (309) is fixedly connected to the surface of the feed hopper (103).

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