Four-path variable-pitch pipette mechanism and pipetting workstation

Abstract

The utility model provides a four-way variable pitch pipette mechanism which comprises a back plate, a four-way pipette module, a first left-right driving mechanism, a second left-right driving mechanism and an interconnection mechanism, and the interconnection mechanism comprises a first connecting rod, a second connecting rod and a third connecting rod. When the first left-right driving mechanism and the second left-right driving mechanism synchronously move at a constant speed, the four pipette modules can be driven to synchronously move at equal intervals, so that displacement in the left-right direction is realized; when the distance between the four pipette modules needs to be adjusted, the first pipette base and the fourth pipette base are driven to stretch or contract through the first left-right driving mechanism or / and the second left-right driving mechanism, and the equal distance adjustment of the pipette heads between the first pipette module, the second pipette module and the fourth pipette module can be completed by means of the linkage effect of the interconnection mechanism; the structure is compact, spacing adjustment is convenient and fast, and the configuration cost is saved.

Description

Technical Field

[0001] The utility model relates to the technical field of pipetting workstations, in particular to a four-channel variable-spacing pipetting gun mechanism and a pipetting workstation. Background Technique

[0002] A pipetting workstation is a device specifically designed for liquid handling in laboratories. Among them, the pipetting gun is the core mechanism for transferring test solutions. In order to improve the pipetting speed, multiple pipetting guns arranged in parallel are usually configured to perform pipetting operations on multiple well positions synchronously. For example, configuring four-channel pipetting guns can significantly improve the pipetting speed. Since the pipetting workstation needs to adapt to well plates with various different well spacings for liquid addition, it is necessary to adjust the four-channel pipetting guns to different equal-spacing position states. At present, each channel of the pipetting gun is separately controlled by its own driving mechanism, and the structure is relatively complex. Content of the Utility Model

[0003] In order to overcome the above-mentioned deficiencies of the prior art, the purpose of the utility model is to provide a four-channel variable-spacing pipetting gun mechanism and a pipetting workstation.

[0004] To achieve the above purpose, the technical solution adopted by the utility model to solve its technical problems is: a four-channel variable-spacing pipetting gun mechanism, including:

[0005] A rear backboard, which is vertically arranged, and a horizontally arranged guide rail is installed on the front side of the rear backboard;

[0006] The first pipetting gun module, which includes a first gun seat and a first pipetting gun. The first gun seat is installed on the guide rail so as to be able to translate left and right, and the first pipetting gun is installed on the first gun seat;

[0007] The second pipetting gun module, which includes a second gun seat and a second pipetting gun. The second gun seat is installed on the guide rail so as to be able to translate left and right, and the second pipetting gun is installed on the second gun seat;

[0008] The third pipetting gun module, which includes a third gun seat and a third pipetting gun. The third gun seat is installed on the guide rail so as to be able to translate left and right, and the third pipetting gun is installed on the third gun seat;

[0009] The fourth pipetting gun module, which includes a fourth gun seat and a fourth pipetting gun. The fourth gun seat is installed on the guide rail so as to be able to translate left and right, and the fourth pipetting gun is installed on the fourth gun seat;

[0010] The first left and right driving mechanism, which is installed on the rear backboard and is used to drive the first gun seat to move left and right;

[0011] The second left and right driving mechanism, which is installed on the rear backboard and is used to drive the fourth gun seat to move left and right;

[0012] An interconnection mechanism, which includes a first connecting rod, a second connecting rod and a third connecting rod. Connecting holes are respectively provided in the middle and at both ends of the first connecting rod. The centers of the three connecting holes of the first connecting rod are on the same straight line, and the distances between the middle connecting hole and the connecting holes at both ends of the first connecting rod are both a; connecting holes are respectively provided at both ends of the second connecting rod, and the distance between the connecting holes at both ends of the second connecting rod is a; connecting holes are respectively provided at both ends of the third connecting rod, and the distance between the connecting holes at both ends of the third connecting rod is a; a first connecting shaft is provided on the back of the second gun holder, and a second connecting shaft is provided on the back of the fourth gun holder. The first connecting shaft and the second connecting shaft are at the same horizontal height. A first vertical sliding groove higher than the height of the first connecting shaft is provided on the back of the first gun holder, and a second vertical sliding groove higher than the height of the first connecting shaft and a third vertical sliding groove lower than the height of the first connecting shaft are provided on the back of the third gun holder; the middle connecting hole of the first connecting rod is rotatably connected to the first connecting shaft, the upper connecting hole of the first connecting rod is slidably connected to the first vertical sliding groove through a third connecting shaft, the lower connecting hole of the first connecting rod and the lower connecting hole of the second connecting rod are slidably connected to the third vertical sliding groove through a fourth connecting shaft, the upper connecting hole of the second connecting rod and the lower connecting hole of the third connecting rod are rotatably connected to the second connecting shaft, and the upper connecting hole of the third connecting rod is slidably connected to the second vertical sliding groove through a fifth connecting shaft.

[0013] Adopting the technical solution of the present utility model, when the first left-right driving mechanism and the second left-right driving mechanism move synchronously and at a constant speed, they can drive the four-channel pipette gun module to move synchronously and at equal intervals, realizing the displacement in the left-right direction; when it is necessary to adjust the distance between the four-channel pipette gun modules, only need to drive the first gun holder and the fourth gun holder to form stretching or contraction through the first left-right driving mechanism or / and the second left-right driving mechanism, and with the linkage effect of the interconnection mechanism, the equal-spacing adjustment of the gun heads between the first to fourth pipette gun modules can be completed; the structure is compact, the distance adjustment is convenient and fast, and the configuration cost is saved.

[0014] Further, bearings are installed at the connection points of the first connecting shaft, the second connecting shaft, the third connecting shaft, the fourth connecting shaft and the fifth connecting shaft with each connecting rod and the vertical sliding groove.

[0015] Adopting the above preferred solution improves the smoothness of the movement of each connecting rod of the interconnection mechanism.

[0016] Further, the guide rails on the back plate include an upper guide rail and a lower guide rail arranged in parallel.

[0017] Adopting the above preferred solution improves the displacement accuracy of each gun holder.

[0018] Further, both the first left - right driving mechanism and the second left - right driving mechanism include a driving motor, a main driving wheel, a driven wheel, and a transmission belt. The main driving wheel is connected to the main shaft of the driving motor, the transmission belt is wound between the main driving wheel and the driven wheel. The transmission belt of the first left - right driving mechanism is connected to the first gun seat through a connecting plate, and the transmission belt of the second left - right driving mechanism is connected to the fourth gun seat through a connecting plate.

[0019] With the above - mentioned preferred solution, the driving mechanism has a simple structural form and a fast response speed.

[0020] Further, a first sliding - groove plate is detachably installed on the first gun seat, and the first vertical sliding groove is arranged on the first sliding - groove plate; a second sliding - groove plate and a third sliding - groove plate are detachably installed on the third gun seat, the second vertical sliding groove is arranged on the second sliding - groove plate, and the third vertical sliding groove is arranged on the third sliding - groove plate.

[0021] With the above - mentioned preferred solution, it is convenient to replace local parts for maintenance after long - term use, reducing the comprehensive use cost.

[0022] A pipetting workstation includes a bottom plate, a bracket, and the above - mentioned four - channel variable - pitch pipetting gun mechanism. A plurality of well - plate placement positions are arranged on the bottom plate, the bracket is fixedly connected to the bottom plate, and the four - channel variable - pitch pipetting gun mechanism is installed on the bracket.

[0023] Further, the rear back - plate of the four - channel variable - pitch pipetting gun mechanism is installed on the bracket through a front - rear guiding mechanism, and a front - rear displacement driving mechanism for driving the rear back - plate to move back and forth is also included.

[0024] With the above - mentioned preferred solution, the front - rear displacement of the pipetting gun module is realized.

[0025] Further, the pipetting guns of each pipetting gun module are installed on their respective gun seats through a lifting driving mechanism.

[0026] With the above - mentioned preferred solution, the up - and - down lifting displacement of each pipetting gun module is realized. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the following drawings are only some embodiments of the present invention. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.

[0028] Figure 1 It is a schematic structural diagram of an implementation manner of the pipetting gun mechanism of the present invention.

[0029] Figure 2 It is a rear schematic view of an implementation manner of the pipetting gun mechanism of the present utility model.

[0030] Figure 3 It is Figure 2 The partial enlarged view at position A in

[0031] Figure 4 It is a structural schematic view of the pipetting workstation of the present utility model.

[0032] The names of the corresponding components indicated by the numbers and letters in the figure:

[0033] 10 - Rear backplate; 11 - Upper guide rail; 12 - Lower guide rail; 13 - First left - right driving mechanism; 131 - Driving motor; 132 - Main driving pulley; 133 - Driven pulley; 134 - Transmission belt; 14 - Second left - right driving mechanism; 20 - First pipetting gun module; 21 - First gun seat; 22 - First pipetting gun; 23 - Lifting driving mechanism; 30 - Second pipetting gun module; 31 - Second gun seat; 32 - Second pipetting gun; 40 - Third pipetting gun module; 41 - Third gun seat; 42 - Third pipetting gun; 50 - Fourth pipetting gun module; 51 - Fourth gun seat; 52 - Fourth pipetting gun; 71 - First connecting rod; 72 - Second connecting rod; 73 - Third connecting rod; 74 - First connecting shaft; 75 - Second connecting shaft; 76 - First vertical sliding groove; 77 - Second vertical sliding groove; 78 - Third vertical sliding groove; 79 - Third connecting shaft; 81 - Fourth connecting shaft; 82 - Fifth connecting shaft; 91 - Bottom plate; 92 - Bracket; 93 - Front - rear displacement driving mechanism. Specific implementation manner

[0034] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present utility model.

[0035] As Figures 1-3 shown, a four - channel variable - pitch pipetting gun mechanism includes:

[0036] A rear backplate 10, which is vertically arranged, and a horizontally arranged upper guide rail 11 and a lower guide rail 12 are installed on the front side of the rear backplate 10;

[0037] A first pipetting gun module 20, which includes a first gun seat 21 and a first pipetting gun 22. The first gun seat 21 is installed on the upper guide rail 11 and the lower guide rail 12 so as to be translatable left and right, and the first pipetting gun 22 is installed on the first gun seat 21;

[0038] The second pipetting gun module 30 includes a second gun base 31 and a second pipetting gun 32. The second gun base 31 is installed on the upper guide rail 11 and the lower guide rail 12 so as to be horizontally translatable, and the second pipetting gun 32 is installed on the second gun base 31;

[0039] The third pipetting gun module 40 includes a third gun base 41 and a third pipetting gun 42. The third gun base 41 is installed on the upper guide rail 11 and the lower guide rail 12 so as to be horizontally translatable, and the third pipetting gun 42 is installed on the third gun base 41;

[0040] The fourth pipetting gun module 50 includes a fourth gun base 51 and a fourth pipetting gun 52. The fourth gun base 51 is installed on the upper guide rail 11 and the lower guide rail 12 so as to be horizontally translatable, and the fourth pipetting gun 52 is installed on the fourth gun base 51; The first gun base 21, the second gun base 31, the third gun base 41, and the fourth gun base 51 are arranged horizontally in sequence from left to right;

[0041] The first left - right driving mechanism 13 is installed on the rear back plate 10 and is used to drive the first gun base 21 to move left and right;

[0042] The second left - right driving mechanism 14 is installed on the rear back plate 10 and is used to drive the fourth gun base 51 to move left and right;

[0043] The interconnecting mechanism includes a first connecting rod 71, a second connecting rod 72, and a third connecting rod 73. Connecting holes are respectively provided in the middle and at both ends of the first connecting rod 71, and the centers of the three connecting holes of the first connecting rod 71 are on the same straight line. The distances between the middle connecting hole and the connecting holes at both ends of the first connecting rod 71 are both a; Connecting holes are respectively provided at both ends of the second connecting rod 72, and the distance between the connecting holes at both ends of the second connecting rod 72 is a; Connecting holes are respectively provided at both ends of the third connecting rod 73, and the distance between the connecting holes at both ends of the third connecting rod 73 is a; A first connecting shaft 74 is provided on the back surface of the second gun base 31, and a second connecting shaft 75 is provided on the back surface of the fourth gun base 51. The first connecting shaft 74 and the second connecting shaft 75 are at the same horizontal height. A first vertical sliding groove 76 higher than the height of the first connecting shaft 74 is provided on the back surface of the first gun base 21, and a second vertical sliding groove 77 higher than the height of the first connecting shaft 74 and a third vertical sliding groove 78 lower than the height of the first connecting shaft 74 are provided on the back surface of the third gun base 41; The middle connecting hole of the first connecting rod 71 is rotatably connected to the first connecting shaft 74, the upper connecting hole of the first connecting rod 71 is slidably connected to the first vertical sliding groove 76 via a third connecting shaft 79, the lower connecting hole of the first connecting rod 71 and the lower connecting hole of the second connecting rod 72 are slidably connected to the third vertical sliding groove 78 via a fourth connecting shaft 81, the upper connecting hole of the second connecting rod 72 and the lower connecting hole of the third connecting rod 73 are rotatably connected to the second connecting shaft 75, and the upper connecting hole of the third connecting rod 73 is slidably connected to the second vertical sliding groove 77 via a fifth connecting shaft 82.

[0044] The beneficial effects of adopting the above technical solution are as follows: when the first left - right driving mechanism and the second left - right driving mechanism move synchronously and at a constant speed, they can drive the four - channel pipetting gun module to move synchronously and at equal intervals, realizing the displacement in the left - right direction; when it is necessary to adjust the distance between the four - channel pipetting gun modules, only by driving the first gun seat and the fourth gun seat to form stretching or contraction through the first left - right driving mechanism or / and the second left - right driving mechanism, and with the linkage effect of the interconnected mechanism, the equal - interval adjustment of the pipette tips between the first to the fourth pipetting gun modules can be completed; the structure is compact, the distance adjustment is convenient and fast, and the configuration cost is saved.

[0045] In some other embodiments of the present utility model, bearings are installed at the joints of the first connecting shaft 74, the second connecting shaft 75, the third connecting shaft 79, the fourth connecting shaft 81 and the fifth connecting shaft 82 with each connecting rod and the vertical sliding groove. The beneficial effect of adopting the above technical solution is: improving the smoothness of the movement of each connecting rod of the interconnected mechanism.

[0046] In some other embodiments of the present utility model, both the first left - right driving mechanism 13 and the second left - right driving mechanism 14 include a driving motor 131, a main transmission wheel 132, a driven wheel 133 and a transmission belt 134. The main transmission wheel 132 is connected to the main shaft of the driving motor 131, and the transmission belt 134 is wound between the main transmission wheel 132 and the driven wheel 133. The transmission belt 134 of the first left - right driving mechanism 13 is connected to the first gun seat 21 through a connecting plate, and the transmission belt of the second left - right driving mechanism 14 is connected to the fourth gun seat 51 through a connecting plate. The beneficial effect of adopting the above technical solution is: the structure form of the driving mechanism is simple, and the action response speed is fast.

[0047] In some other embodiments of the present utility model, a first sliding groove plate is detachably installed on the first gun seat 21, and the first vertical sliding groove 76 is arranged on the first sliding groove plate; a second sliding groove plate and a third sliding groove plate are detachably installed on the third gun seat 41, the second vertical sliding groove 77 is arranged on the second sliding groove plate, and the third vertical sliding groove 78 is arranged on the third sliding groove plate. The beneficial effect of adopting the above technical solution is: facilitating the replacement of local accessories for maintenance after long - term use and wear, and reducing the comprehensive use cost.

[0048] As Figure 4 shown, a pipetting workstation includes a bottom plate 91, a bracket 92 and the above - mentioned four - channel variable - distance pipetting gun mechanism. A plurality of well - plate placement positions are arranged on the bottom plate 91, the bracket 92 is fixedly connected to the bottom plate 91, and the four - channel variable - distance pipetting gun mechanism is installed on the bracket.

[0049] In some other embodiments of the present utility model, the rear back plate 10 of the four-way variable pitch pipette mechanism is installed on the bracket 92 through a front and rear guiding mechanism, and further includes a front and rear displacement driving mechanism 93 for driving the rear back plate 10 to move back and forth. The beneficial effect of adopting the above technical solution is: realizing the back-and-forth displacement of the pipette module.

[0050] As Figure 1 shown, in some other embodiments of the present utility model, the pipettes of each pipette module are installed on their respective pipette holders through a lifting driving mechanism 23. The beneficial effect of adopting the above technical solution is: realizing the up-and-down lifting displacement of each pipette module.

[0051] The above embodiments are only used to illustrate the technical concept and characteristics of the present utility model, and the purpose is to enable those of ordinary skill in the art to understand the content of the present utility model and implement it. It cannot be used to limit the protection scope of the present utility model. Any equivalent changes or modifications made according to the spirit of the present utility model should be covered within the protection scope of the present utility model.

Claims

1. A four-channel variable-pitch pipetting gun mechanism, characterized in that, Comprising: A rear backboard, which is vertically arranged, and a horizontally arranged guide rail is installed on the front side surface of the rear backboard; A first pipette module, which includes a first gun seat and a first pipette. The first gun seat is installed on the guide rail so as to be movable left and right, and the first pipette is installed on the first gun seat; A second pipette module, which includes a second gun seat and a second pipette. The second gun seat is installed on the guide rail so as to be movable left and right, and the second pipette is installed on the second gun seat; A third pipette module, which includes a third gun seat and a third pipette. The third gun seat is installed on the guide rail so as to be movable left and right, and the third pipette is installed on the third gun seat; A fourth pipette module, which includes a fourth gun seat and a fourth pipette. The fourth gun seat is installed on the guide rail so as to be movable left and right, and the fourth pipette is installed on the fourth gun seat; A first left and right driving mechanism, which is installed on the rear backboard and is used for driving the first gun seat to move left and right; A second left and right driving mechanism, which is installed on the rear backboard and is used for driving the fourth gun seat to move left and right; An interconnecting mechanism, which includes a first connecting rod, a second connecting rod and a third connecting rod. Connecting holes are respectively arranged in the middle and at both ends of the first connecting rod, and the centers of the three connecting holes of the first connecting rod are on the same straight line. The distances between the middle connecting hole and the connecting holes at both ends of the first connecting rod are both a; Connecting holes are respectively arranged at both ends of the second connecting rod, and the distance between the connecting holes at both ends of the second connecting rod is a; Connecting holes are respectively arranged at both ends of the third connecting rod, and the distance between the connecting holes at both ends of the third connecting rod is a; A first connecting shaft is arranged on the back surface of the second gun seat, and a second connecting shaft is arranged on the back surface of the fourth gun seat. The first connecting shaft and the second connecting shaft are at the same horizontal height. A first vertical sliding groove higher than the height of the first connecting shaft is arranged on the back surface of the first gun seat, and a second vertical sliding groove higher than the height of the first connecting shaft and a third vertical sliding groove lower than the height of the first connecting shaft are arranged on the back surface of the third gun seat; The middle connecting hole of the first connecting rod is rotatably connected to the first connecting shaft, the upper connecting hole of the first connecting rod is slidably connected to the first vertical sliding groove through a third connecting shaft, the lower connecting hole of the first connecting rod and the lower connecting hole of the second connecting rod are slidably connected to the third vertical sliding groove through a fourth connecting shaft, the upper connecting hole of the second connecting rod and the lower connecting hole of the third connecting rod are rotatably connected to the second connecting shaft, and the upper connecting hole of the third connecting rod is slidably connected to the second vertical sliding groove through a fifth connecting shaft.

2. The four-channel variable pitch pipetting gun mechanism according to claim 1, wherein Bearings are installed at the connection parts of the first connecting shaft, the second connecting shaft, the third connecting shaft, the fourth connecting shaft and the fifth connecting shaft with each connecting rod and the vertical sliding groove.

3. The four-channel variable-pitch pipette mechanism according to claim 1, wherein, The guide rail on the rear backboard includes an upper guide rail and a lower guide rail arranged in parallel.

4. The four-channel variable pitch pipette mechanism according to claim 3, characterized in that, The first left-right driving mechanism and the second left-right driving mechanism both include a driving motor, a main driving wheel, a driven wheel and a transmission belt. The main driving wheel is connected to the main shaft of the driving motor. The transmission belt is wound between the main driving wheel and the driven wheel. The transmission belt of the first left-right driving mechanism is connected to the first gun seat through a connecting plate, and the transmission belt of the second left-right driving mechanism is connected to the second gun seat through a connecting plate.

5. The four-channel variable-pitch pipette mechanism according to claim 1, wherein, A first chute plate is detachably mounted on the first gun seat, and the first vertical chute is arranged on the first chute plate; a second chute plate and a third chute plate are detachably mounted on the third gun seat, the second vertical chute is arranged on the second chute plate, and the third vertical chute is arranged on the third chute plate.

6. A pipetting workstation, characterized in that, It includes a bottom plate, a bracket and the four-channel variable-pitch pipetting gun mechanism described in claim 1. A plurality of orifice plate placement positions are arranged on the bottom plate. The bracket is fixedly connected to the bottom plate, and the four-channel variable-pitch pipetting gun mechanism is mounted on the bracket.

7. The pipetting workstation according to claim 6, wherein The rear back plate of the four-channel variable-pitch pipetting gun mechanism is mounted on the bracket through a front-back guiding mechanism, and a front-back displacement driving mechanism for driving the rear back plate to move back and forth is further included.

8. The pipetting workstation according to claim 7, wherein The pipetting guns of each pipetting gun module are all mounted on their respective gun seats through a lifting driving mechanism.

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