Elisa batten injection mold

Abstract

The utility model relates to the technical field of elisa batten injection molds, and provides an elisa batten injection mold which at least comprises a mold cavity used for injection molding of an elisa batten; the pouring gate is arranged at the position, corresponding to the edge of the bottom of the reaction hole of the elisa plate strip, of the mold cavity, so that after injection molding materials for injection molding enter the mold cavity through the pouring gate, a cavity corresponding to the bottom of the elisa plate strip is filled with the injection molding materials, and then the injection molding materials are filled from the cavity corresponding to the bottom of the elisa plate strip to the cavity corresponding to the opening of the elisa plate strip. According to the elisa strip injection mold, it can be ensured that glue is fully injected into the bottom of an elisa strip, so that the elisa strip with the smooth and flat hole bottom is obtained, the position where herringbone flow lines are formed or the position where the flatness is poor is located at the opening of the elisa strip, the position does not involve the enzyme-linked immunosorbent assay (ELISA) reaction, the result is not affected, and the inter-hole CV value is not affected either.

Description

Technical Field

[0001] The utility model relates to the technical field of injection molds for enzyme-linked immunosorbent assay (ELISA) strip, and particularly relates to an injection mold for ELISA strip. Background Art

[0002] Flat-bottom ELISA strips are mainly used in laboratories to carry various necessary experimental supplies, and play a very crucial role in conditions such as antigens, antibodies, labeled antibodies, buffer solutions, etc. involved in immunological reactions. Its working principle is to fix a certain concentration of antigen or antibody on the surface of a polystyrene microplate by physical adsorption method, add the specimen to be detected, and indirectly reflect the presence or absence or amount of the antigen or antibody to be detected by detecting the color depth of the enzyme-labeled substance on an enzyme-labeled detector. At this time, the smoothness and flatness of the bottom of each reaction well of the ELISA strip and the uniformity of light transmittance are extremely important, and the quality directly affects the detection result and the coefficient of variation (CV) value between wells of the ELISA strip. In a conventional injection mold for ELISA strip, the gate is located on the side of the mold cavity. The injection material enters from the gate, first fills the cavity corresponding to the side of the ELISA strip in the mold cavity, and then fills from the side in two directions: up and down. However, such a structural design of the injection mold has very strict requirements for injection conditions. When the temperature is too high, the injection volume is slightly low, or the machine is not stable enough, it is very easy to generate herringbone flow marks at the bottom of the ELISA strip, or the flatness of the bottom of the well is poor, and in severe cases, even cavities are generated. Summary of the Utility Model

[0003] Therefore, the technical problem to be solved by the utility model is that in the prior art, the gate of the injection mold is set on the side of the mold cavity, which is easy to generate herringbone flow marks at the bottom of the reaction well of the ELISA strip, or the flatness of the bottom of the well is poor, and in severe cases, even cavities are generated. Thus, an injection mold for ELISA strip is provided.

[0004] To solve the above technical problem, the technical solution of the utility model is as follows:

[0005] The utility model provides an injection mold for ELISA strip, which at least includes: a mold cavity for injecting an ELISA strip; a gate set at the position corresponding to the bottom edge of the reaction well of the ELISA strip in the mold cavity, so that the injection material for injection enters the mold cavity through the gate, first fills the cavity corresponding to the bottom of the ELISA strip, and then fills from the cavity corresponding to the bottom of the ELISA strip in the direction of the cavity corresponding to the opening of the ELISA strip.

[0006] Further, along the length direction of the mold cavity, each mold cavity is divided into multiple sub-cavities, and each sub-cavity is adaptively provided with a gate.

[0007] Further, the microplate strip injection mold further includes a hot main runner, a hot sub-runner and a hot branch runner; the hot main runner has a plurality of outlets, and each outlet of the hot main runner is connected to a hot sub-runner; each outlet of the hot sub-runner is connected to a plurality of hot branch runners; the outlets of the hot branch runners are communicated with the gates.

[0008] Further, the outlet end of each hot branch runner bifurcates into two outlets, so that a single hot branch runner is adapted to be arranged adjacent to two of the sub-cavities.

[0009] Further, the microplate strip injection mold further includes a water conveying pipeline; a plurality of rows of the mold cavities are arranged at intervals along the length direction perpendicular to the mold cavity, the water conveying pipeline is arranged between two adjacent rows of the mold cavities, and the water conveying pipeline is arranged parallel to the mold cavity; a water body with adjustable temperature is arranged in the water conveying pipeline.

[0010] Further, the height of the water conveying pipeline is kept consistent with the height of the gate.

[0011] Further, the diameter range of the gate is 0.3 mm - 0.35 mm.

[0012] Further, the diameter of the gate is 0.3 mm.

[0013] The technical solution of the present utility model has the following advantages:

[0014] In the microplate strip injection mold provided by the present utility model, the gate is arranged at the position of the mold cavity corresponding to the bottom edge of the reaction hole of the microplate strip, that is, the gate is located at the top of the mold cavity. After the injection material for injection enters the mold cavity through the gate, it first fills the cavity corresponding to the bottom of the microplate strip, and then fills from the cavity corresponding to the bottom of the microplate strip to the cavity corresponding to the opening (the bottom of the mold cavity) of the microplate strip. With such a setting, it can ensure sufficient injection of glue at the bottom of the microplate strip, so as to obtain a microplate strip with a smooth and flat bottom of the hole, and the part where herringbone flow marks or poor flatness are formed is located at the opening of the microplate strip, and this part does not involve ELISA (enzyme linked immunosorbent assay) reaction, has no influence on the result, and will not affect the CV value between holes. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] In order to more clearly illustrate the specific embodiments of the present utility model or the technical solutions in the prior art, the following will briefly introduce the drawings required for use in the description of the specific embodiments or the prior art. Obviously, the drawings in the following description are some embodiments of the present utility model. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.

[0016] Figure 1 Schematic diagram of the injection mold for the enzyme-linked immunosorbent assay (ELISA) strip in the embodiment of the present utility model;

[0017] Figure 2 Side view of the injection mold for the enzyme-linked immunosorbent assay (ELISA) strip in the embodiment of the present utility model;

[0018] Figure 3 is Figure 2 Enlarged schematic diagram of part A in

[0019] Explanation of reference numerals:

[0020] 1. Mold cavity; 2. Gate; 3. Hot sub-runner; 4. Hot main runner; 5. Hot sub-runner; 6. Water pipeline. Specific implementation manners

[0021] Next, the technical solutions of the present utility model will be clearly and completely described in conjunction with the accompanying drawings. Obviously, the described embodiments are part of the embodiments of the present utility model, rather than all of them. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without creative efforts shall fall within the protection scope of the present utility model.

[0022] In the description of the present utility model, it should be noted that the orientation or positional relationship indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. is based on the orientation or positional relationship shown in the accompanying drawings. It is only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present utility model. In addition, the terms "first", "second", "third" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance.

[0023] In the description of the present utility model, it should be noted that unless otherwise clearly specified and limited, the terms "installation", "connection", "connection" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the communication inside two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific situations.

[0024] In addition, the technical features involved in different embodiments of the present utility model described below can be combined with each other as long as they do not conflict with each other.

[0025] Such as Figures 1 to 3As shown in the figure, this embodiment provides an injection mold for an ELISA plate strip, which at least includes: a mold cavity 1, the space inside the mold cavity 1 is adapted to the shape and size of the ELISA plate strip. After adding the injection plastic heated and melted into the mold cavity 1 and cooling it, an ELISA plate strip can be obtained; a gate 2. In this embodiment, the opening of the ELISA plate strip formed by the mold cavity 1 faces downward, so the gate 2 should be located at the top of the mold cavity 1. The position of the gate 2 on the mold cavity 1 corresponds to the bottom edge position of the reaction holes of the ELISA plate strip, so that the injection plastic for injection enters the mold cavity 1 through the gate 2 and first fills the cavity corresponding to the bottom of the ELISA plate strip, and then fills from the cavity corresponding to the bottom of the ELISA plate strip to the cavity corresponding to the opening of the ELISA plate strip.

[0026] For the injection mold for an ELISA plate strip provided in this embodiment, the gate 2 is arranged at the position corresponding to the bottom edge of the reaction holes of the ELISA plate strip, that is, the gate 2 is located at the top of the mold cavity 1. The injection plastic for injection enters the mold cavity 1 through the gate 2 and first fills the cavity corresponding to the bottom of the ELISA plate strip, and then fills from the cavity corresponding to the bottom of the ELISA plate strip to the cavity corresponding to the opening (the bottom of the mold cavity 1) of the ELISA plate strip. With such a setting, it can ensure sufficient injection of glue at the bottom of the ELISA plate strip, so as to obtain an ELISA plate strip with a smooth and flat bottom of the hole, while the part with herringbone flow marks or poor flatness is located at the opening of the ELISA plate strip. This part does not involve the ELISA (enzyme linked immunosorbent assay) reaction, has no influence on the result, and will not affect the CV value between holes.

[0027] Among them, along the length direction of the mold cavity 1, each mold cavity 1 can be divided into multiple sub-cavities, and each sub-cavity is adaptively provided with a gate 2. For example, in the production of an eight-well ELISA plate strip, along the length direction of the mold cavity 1, each mold cavity 1 can be divided into eight sub-cavities, that is, a single mold cavity 1 can form an eight-well ELISA plate strip by single injection molding.

[0028] Such as Figure 2 、 Figure 3As shown in the figure, the injection mold for the enzyme-linked immunosorbent assay (ELISA) plate strip further includes a hot main runner 4, a hot sub-runner 5, and a hot branch runner 3. The hot main runner 4 has a plurality of outlets, and each outlet of the hot main runner 4 is connected to a hot sub-runner 5. Each outlet of the hot sub-runner 5 is connected to a plurality of hot branch runners 3. The outlet of the hot branch runner 3 is communicated with the gate 2. Taking the injection molding material as a medical-grade polystyrene material as an example, during injection molding, the injection molding material is heated to 260 °C in the barrel of the injection molding machine until it melts, and then enters the mold cavity 1 through the hot main runner 4, the hot sub-runner 5, the hot branch runner 3, and the gate 2 in sequence. With such a setting, according to the number of mold cavities 1, the required number of hot sub-runners 5 and hot branch runners 3 can be selected, so that multiple ELISA plate strips can be produced in a single injection molding. Moreover, compared with separately equipping each mold cavity 1 with a hot sub-runner 5, the setting of the hot branch runner 3 can reduce the number of hot sub-runners 5, the overall mold structure is simple, the cost is low, and the molding effect is good, and it can meet the requirements of smooth and flat bottom and high uniformity of light transmittance for each hole.

[0029] Among them, two outlets are branched out from the outlet end of each hot branch runner 3 so that a single hot branch runner 3 is adapted to two adjacent sub-cavities. When each mold cavity 1 includes eight sub-cavities, four hot branch runners 3 can be used to realize the injection molding of a single mold cavity 1. With such a setting, the overall mold is more streamlined and the cost is lower.

[0030] As Figure 1 shown in the figure, the injection mold for the ELISA plate strip further includes a water conveying pipeline 6. A plurality of rows of mold cavities 1 are arranged at intervals along the length direction perpendicular to the mold cavity 1. The water conveying pipeline 6 is arranged between two adjacent rows of mold cavities 1 and is parallel to the mold cavity 1. A water body with adjustable temperature is arranged in the water conveying pipeline 6. For example, the height of the water conveying pipeline 6 can be kept consistent with the height of the gate 2. During use, after the water body flows in the water conveying pipeline 6, the heat in the mold cavity 1 can be taken away by using heat radiation. With such a setting, the injection molding material can meet the injection molding requirements while maintaining good fluidity, and at the same time, it can also achieve the effect of cooling and solidifying the gate 2 and the product, so as to accurately control the flow pressure, speed, and temperature of the injection molding material, so that the bottom of each hole of the ELISA plate strip is smoother and flatter, and the light transmittance uniformity is higher.

[0031] Among them, the diameter range of the gate 2 can be 0.3 mm - 0.35 mm. Preferably, the diameter of the gate 2 can be 0.3 mm. If the gate 2 is too large, serious residue will occur at the fracture of the gate 2, affecting the appearance and performance of the product. Because if the gate 2 is too large or the temperature of the injection molding material is too high, the curing time is long, and the gate 2 is not cured at the end of the injection molding process. During the mold separation process, long burrs will be formed after being pulled, and it is easy to cut the protective supplies such as the user's gloves during use. If the gate 2 is too small, the injection molding time is too long and the pressure is too high.

[0032] Obviously, the above embodiments are merely examples for clear illustration and not limitations on the implementation manners. For those of ordinary skill in the art, other different forms of changes or variations can be made based on the above description. It is not necessary and impossible to enumerate all implementation manners here. And the obvious changes or variations derived therefrom still fall within the protection scope of the creation of the present utility model.

Claims

1. An injection mold for an enzyme-labeled plate strip, characterized in that, At least including: A mold cavity (1) for injection molding an ELISA plate strip; A gate (2) is arranged at a position of the mold cavity (1) corresponding to the bottom edge of the reaction holes of the ELISA plate strip, so that the injection material for injection molding enters the mold cavity (1) through the gate (2), first fills the cavity corresponding to the bottom of the ELISA plate strip, and then fills from the cavity corresponding to the bottom of the ELISA plate strip towards the cavity corresponding to the opening of the ELISA plate strip.

2. The ELISA plate strip injection mold according to claim 1, characterized in that Along the length direction of the mold cavity (1), each mold cavity (1) is divided into a plurality of sub-cavities, and each sub-cavity is adaptively provided with a gate (2).

3. The ELISA plate strip injection mold according to claim 2, characterized in that It further includes a hot main runner (4), a hot sub-runner (5) and a hot branch runner (3); The hot main runner (4) has a plurality of outlets, and each outlet of the hot main runner (4) is connected to a hot sub-runner (5); Each outlet of the hot sub-runner (5) is connected to a plurality of the hot branch runners (3); The outlet of the hot branch runner (3) is communicated with the gate (2).

4. The ELISA plate strip injection mold according to claim 3, characterized in that The outlet end of each hot branch runner (3) branches into two outlets, so that a single hot branch runner (3) is arranged adaptively to two adjacent sub-cavities.

5. The ELISA plate strip injection mold according to claim 3, characterized in that It further includes a water conveying pipeline (6); A plurality of rows of the mold cavities (1) are arranged at intervals along the direction perpendicular to the length direction of the mold cavity (1), the water conveying pipeline (6) is arranged between two adjacent rows of the mold cavities (1), and the water conveying pipeline (6) is arranged parallel to the mold cavity (1); The water conveying pipeline (6) is internally provided with a water body with adjustable temperature.

6. The ELISA plate strip injection mold according to claim 5, characterized in that The height of the water conveying pipeline (6) is kept consistent with the height of the gate (2).

7. The ELISA plate strip injection mold according to claim 1, characterized in that The diameter range of the gate (2) is 0.3 mm - 0.35 mm.

8. The ELISA plate strip injection mold according to claim 7, characterized in that The diameter of the gate (2) is 0.3 mm.

Images