Microbial separation device for tablet medicines

Abstract

The utility model provides a microbiological separation device for tablet medicines, which relates to the technical field of medicine inspection and comprises a separation shell, a fixed grinding wheel is mounted at the top of the inner side of the separation shell in a sliding manner; a positioning carrier plate is mounted at the bottom of the inner side of the separation shell; a driving motor is mounted in the middle of the bottom of the positioning carrier plate; a collecting barrel is mounted at the top of the positioning carrier plate; a collecting barrel is mounted on the inner side of the separation shell, and a flow guide nozzle is arranged on the side face of the collecting barrel; a refrigeration water tank is mounted on the outer side of the separation shell; a water pump is mounted at the top of the refrigeration water tank, and a water pump is mounted at the bottom of the refrigeration water tank. Refrigeration water flow flows in the circulating pipe to cool the fixed grinding wheel used for grinding, the situation that the activity of microorganisms is affected by the high temperature of grinding is prevented, and the problem that the activity of the microorganisms is affected by heat generated in the grinding process due to the fact that medicine is ground into powder and added into a solution to obtain the microorganisms is solved.

Description

Technical Field

[0001] The utility model relates to the technical field of drug inspection, in particular to a microbial separation device for tablet drugs. Background Art

[0002] Tablet drugs are solid preparation drugs in the form of tablets or special-shaped tablets pressed after uniform mixing of drugs and excipients. When performing microbial inspection on tablet drugs, a separation device is needed to separate the microorganisms in the drugs, so as to facilitate the microbial inspection of the drugs and ensure the quality and safety of the drugs. In the prior art, when separating the microorganisms in tablet drugs, the drugs are usually ground into powder and added to a solution to obtain the microorganisms. However, heat is generated during the grinding process, and the generated certain heat will affect the activity of the microorganisms, resulting in a large error in the detection results of the microorganisms. Summary of the Invention

[0003] The embodiments of the present disclosure relate to a microbial separation device for tablet drugs, so as to solve the problem that in the prior art, when separating the microorganisms in tablet drugs, the drugs are usually ground into powder and added to a solution to obtain the microorganisms. However, heat is generated during the grinding process, and the generated certain heat will affect the activity of the microorganisms, resulting in a large error in the detection results of the microorganisms.

[0004] In the first aspect of the present disclosure, a microbial separation device for tablet drugs is provided, which specifically includes: a separation housing, the separation housing is of a cylindrical structure, and adjusting bolts are installed on both sides of the top of the separation housing, and a fixed grinding wheel is slidably installed on the inner top of the separation housing; the bottom of the fixed grinding wheel is of a conical structure, and the two sides of the top of the fixed grinding wheel are connected to the bottoms of the adjusting bolts on both sides of the top of the separation housing; a positioning carrier plate is installed on the inner bottom of the separation housing; a driving motor is installed at the middle position of the bottom of the positioning carrier plate, and a discharge port is also provided at the bottom of the positioning carrier plate; a collection cylinder is installed on the top of the positioning carrier plate; the collection cylinder is installed inside the separation housing, and a diversion nozzle is provided on the side of the collection cylinder, and the diversion nozzle penetrates through the outside of the separation housing; a refrigeration water tank is installed on the outside of the separation housing; a water pump is installed on the top of the refrigeration water tank, and a water pump is also installed on the bottom of the refrigeration water tank, and a water outlet pipe is installed on the output end of the water pump.

[0005] Further, a feed cover is connected to the middle position of the top of the separation housing, wherein the top of the feed cover is of a conical structure; a fixed support plate is also installed inside the separation housing; a servo motor is installed at the bottom of the fixed support plate, and a plurality of slots are provided on the side of the fixed support plate, and a rotating grinding wheel is installed on the top of the fixed support plate; the bottom of the rotating grinding wheel is connected to the output end of the servo motor at the bottom of the fixed support plate, and the rotating grinding wheel is rotatably installed below the fixed grinding wheel.

[0006] Furthermore, a fixing bracket is installed at the top of the separation housing; a solution storage tank is installed at the top of the fixing bracket; a diversion vertical pipe is installed at the bottom of the solution storage tank; a control valve is installed on the diversion vertical pipe; a diversion pipe is installed inside the feed cover; the diversion pipe is of a circular structure, and water outlet holes are provided at the bottom of the diversion pipe, and the diversion pipe is connected to the bottom of the diversion vertical pipe.

[0007] Furthermore, a diversion plate is installed at the inner bottom of the collection cylinder; a rotating cylinder is rotatably installed at the middle position of the top of the positioning carrier plate; filtering holes are provided on the side of the rotating cylinder, and the bottom of the rotating cylinder is connected to the output end of a driving motor at the bottom of the positioning carrier plate, and the rotating cylinder is rotatably installed inside the collection cylinder.

[0008] Furthermore, a guiding plate is installed inside the separation housing; the guiding plate is of a conical structure, and the guiding plate is located below the fixed support plate and above the rotating cylinder; a cup holder is installed at the outer bottom of the separation housing; a collection cup is placed on the cup holder; the collection cup is located below the diversion nozzle on the side of the collection cylinder.

[0009] Furthermore, a refrigeration pipe is installed through the bottom of the water outlet pipe and the separation housing; the refrigeration pipe is of a circular structure, and the refrigeration pipe is installed at the bottom of the positioning carrier plate, and a diversion pipe is installed on the side of the refrigeration pipe; the diversion pipe penetrates through the outer side of the separation housing and is installed inside the fixed grinding wheel.

[0010] Furthermore, a circulation pipe is installed inside the fixed grinding wheel; the circulation pipe is of a spiral structure, one end of the circulation pipe is connected to the diversion pipe, and the other end of the circulation pipe is connected to a return pipe; the return pipe penetrates through the separation housing and is connected to the top of the refrigeration water tank.

[0011] The utility model provides a tablet drug microorganism separation device, which has the following beneficial effects:

[0012] When the utility model is in use, the fixed grinding wheel used for grinding is cooled by the flowing of the refrigerated water flow in the circulation pipe, preventing the high temperature during grinding from affecting the activity of microorganisms. When separating the microorganisms from the tablet drug, the rotating grinding wheel and the fixed grinding wheel grind the drug into powder. At the same time, the refrigerated water flow enters the circulation pipe through the diversion pipe. The circulation pipe is inside the fixed grinding wheel close to the grinding surface, cooling the grinding surface and cooling the ground drug, keeping the microorganisms in the initial state, preventing the heat generated during grinding from affecting the activity of microorganisms, and ensuring the accuracy of the later microorganism project test results.

[0013] In addition, the water flow flowing out through the shunt pipe is uniformly mixed with the ground medicine, which is convenient for precipitating solid substances to obtain a solution containing microorganisms. When separating microorganisms from tablet drugs, during the grinding process, the water flow in the solution storage tank flushes the powdered medicine on the rotating grinding wheel through the shunt pipe, ensuring the cleanliness of the rotating grinding wheel and the fixed grinding wheel. Moreover, the water flow is shunted and flushed to be uniformly mixed with the medicine, and a solution containing microorganisms can be precipitated after standing. The structure is simple and the operation is convenient, and the microorganisms in the medicine can be obtained relatively completely. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings of the embodiments will be briefly introduced below.

[0015] The drawings in the following description only relate to some embodiments of the present invention and do not limit the present invention.

[0016] In the drawings:

[0017] Figure 1 A schematic diagram showing the overall structure of the present application is shown;

[0018] Figure 2 A schematic cross-sectional structure diagram of the separation housing of the present application is shown;

[0019] Figure 3 A schematic three-dimensional structure diagram of the positioning carrier plate of the present application is shown;

[0020] Figure 4 A schematic cross-sectional structure diagram of the rotating cylinder of the present application is shown;

[0021] Figure 5 A schematic three-dimensional structure diagram of the refrigeration water tank of the present application is shown;

[0022] Figure 6 A schematic three-dimensional structure diagram of the circulation pipe of the present application is shown;

[0023] LIST OF REFERENCE NUMERALS

[0024] 1. Separation housing; 101. Feed cover; 102. Fixed grinding wheel; 103. Fixed support plate; 104. Rotating grinding wheel; 105. Fixed bracket; 106. Solution storage tank; 107. Guide vertical pipe; 108. Shunt pipe;

[0025] 2. Positioning carrier plate; 201. Collection cylinder; 202. Guide plate; 203. Rotating cylinder; 204. Guide plate; 205. Cup support; 206. Collection cup;

[0026] 3. Refrigeration water tank; 301. Water outlet pipe; 302. Refrigeration pipe; 303. Guide pipe; 304. Circulation pipe; 305. Return pipe. Detailed implementation mode

[0027] To make the objectives, technical solutions and advantages of the embodiments of the present utility model clearer, the technical solutions of the embodiments of the present utility model will be clearly and completely described below in conjunction with the drawings of the embodiments of the present utility model. Obviously, the described embodiments are some, but not all, of the embodiments of the present utility model. All other embodiments obtained by those of ordinary skill in the art based on the described embodiments of the present utility model without creative efforts shall fall within the scope of protection of the present utility model.

[0028] Please refer to Figures 1 to 6 :

[0029] Embodiment 1:

[0030] The present utility model provides a microbial separation device for tablet drugs, including: a separation housing 1, the separation housing 1 is of a cylindrical structure, and adjusting bolts are installed on both sides of the top of the separation housing 1, and a fixed grinding wheel 102 is slidably installed on the inner top of the separation housing 1; the bottom of the fixed grinding wheel 102 is of a conical structure, and the two sides of the top of the fixed grinding wheel 102 are connected to the bottoms of the adjusting bolts on both sides of the top of the separation housing 1; a feed cover 101 is connected to the middle position of the top of the separation housing 1, wherein the top of the feed cover 101 is of a conical structure; a fixed support plate 103 is further installed inside the separation housing 1; a servo motor is installed at the bottom of the fixed support plate 103, and there are multiple slots on the side of the fixed support plate 103, and a rotating grinding wheel 104 is installed on the top of the fixed support plate 103; the bottom of the rotating grinding wheel 104 is connected to the output end of the servo motor at the bottom of the fixed support plate 103, and the rotating grinding wheel 104 is rotatably installed below the fixed grinding wheel 102; a fixed bracket 105 is installed on the top of the separation housing 1; a solution storage tank 106 is installed on the top of the fixed bracket 105; a diversion vertical pipe 107 is installed at the bottom of the solution storage tank 106; a control valve is installed on the diversion vertical pipe 107; a diversion pipe 108 is installed inside the feed cover 101; the diversion pipe 108 is of an annular structure, and water outlet holes are provided at the bottom of the diversion pipe 108, and the diversion pipe 108 is connected to the bottom of the diversion vertical pipe 107.

[0031] In the embodiments of the present disclosure, when separating microorganisms from tablet drugs, the position of the fixed grinding wheel 102 is adjusted according to the fineness of the required drug powder. The adjusting screw is rotated on both sides of the top of the separation housing 1 to drive the fixed grinding wheel 102 to adjust its height, so that an appropriate distance is maintained between the fixed grinding wheel 102 and the rotating grinding wheel 104. The servo motor at the bottom of the fixed support plate 103 drives the rotating grinding wheel 104 to rotate below the fixed grinding wheel 102. The tablet drug is fed through the feeding cover 101 between the fixed grinding wheel 102 and the rotating grinding wheel 104. The rotating grinding wheel 104 rotates to grind the drug into powder. The specific water in the solution storage tank 106 at the top of the fixed bracket 105 flows downward through the diversion vertical pipe 107. The water flow flows onto the rotating grinding wheel 104 through the diversion pipe 108. The water flow flushes the rotating grinding wheel 104 and the fixed grinding wheel 102, and the water flow carries the powdered drug and flows down through the slot on the side of the fixed support plate 103 for separation.

[0032] Embodiment 2, on the basis of Embodiment 1, a positioning carrier plate 2 is installed at the inner bottom of the separation housing 1; a driving motor is installed at the middle position of the bottom of the positioning carrier plate 2, and a discharge port is also provided at the bottom of the positioning carrier plate 2; a collection cylinder 201 is installed on the top of the positioning carrier plate 2; the collection cylinder 201 is installed inside the separation housing 1, and a diversion nozzle is provided on the side of the collection cylinder 201, and the diversion nozzle penetrates through the outside of the separation housing 1; a diversion plate 202 is installed at the inner bottom of the collection cylinder 201; a rotating cylinder 203 is rotatably installed at the middle position of the top of the positioning carrier plate 2; filter holes are provided on the side of the rotating cylinder 203, and the bottom of the rotating cylinder 203 is connected to the output end of the driving motor at the bottom of the positioning carrier plate 2, and the rotating cylinder 203 is rotatably installed inside the collection cylinder 201; a guiding plate 204 is installed inside the separation housing 1; the guiding plate 204 is of a conical structure, and the guiding plate 204 is located below the fixed support plate 103 and above the rotating cylinder 203; a cup holder 205 is installed at the outer bottom of the separation housing 1; a collection cup 206 is placed on the cup holder 205; the collection cup 206 is located below the diversion nozzle on the side of the collection cylinder 201. When performing microbial separation on tablet drugs, the guiding plate 204 guides the powder and water flow into the inside of the rotating cylinder 203. The obtained drug solution is stored inside the rotating cylinder 203. Part of the solution carrying microorganisms flows into the inside of the collection cylinder 201 through the filter holes on the side. After the powder solution stands for a period of time, the driving motor at the bottom of the positioning carrier plate 2 drives the rotating cylinder 203 to rotate. The centrifugal force generated by the rotation of the rotating cylinder 203 causes the solution carrying microorganisms to flow into the inside of the collection cylinder 201 through the filter holes. The diversion plate 202 diverts the solution, and the solution carrying microorganisms flows into the collection cup 206 on the cup holder 205 through the collection cylinder 201, which is convenient for using an instrument to detect the microorganisms in the drug. There is a discharge port at the bottom of the rotating cylinder 203. When the rotating cylinder 203 rotates to a certain position and coincides with the discharge port at the bottom of the positioning carrier plate 2, the solid matter is cleared out.

[0033] Embodiment 3: On the basis of Embodiment 1, a refrigeration water tank 3 is installed on the outer side of the separation housing 1; a water pump is installed on the top of the refrigeration water tank 3, and a water pump is also installed on the bottom of the refrigeration water tank 3. An outlet pipe 301 is installed on the output end of the water pump; the bottom of the outlet pipe 301 penetrates through the separation housing 1 and is installed with a refrigeration pipe 302; the refrigeration pipe 302 is of an annular structure, and the refrigeration pipe 302 is installed at the bottom of the positioning carrier plate 2, and a diversion pipe 303 is installed on the side of the refrigeration pipe 302; the diversion pipe 303 penetrates through the outer side of the separation housing 1 and is installed inside the fixed grinding wheel 102; a circulation pipe 304 is installed inside the fixed grinding wheel 102; the circulation pipe 304 is of a spiral structure, and one end of the circulation pipe 304 is connected to the diversion pipe 303, and the other end of the circulation pipe 304 is connected to a return pipe 305; the return pipe 305 penetrates through the separation housing 1 and is connected to the top of the refrigeration water tank 3. When performing microbial separation on tablet drugs, during the drug grinding and separation process, the refrigerated water flow in the refrigeration water tank 3 flows through the outlet pipe 301 into the refrigeration pipe 302 under the action of the water pump to cool the collected solution and prevent the change in temperature from affecting the activity of microorganisms. The water flows to the diversion pipe 303 and then enters the inside of the circulation pipe 304. The circulation pipe 304 is located inside the grinding surface of the fixed grinding wheel 102 to cool the grinding position and prevent heat generated during the grinding process from affecting the activity of microorganisms. The water flows back to the refrigeration water tank 3 through the return pipe 305 for refrigeration and then circulates again, ensuring that the whole separation process will not be affected by temperature, ensuring that the microorganisms are in the initial state, and ensuring the accuracy of the microbial test results.

[0034] Working principle of this embodiment: During use, the servo motor at the bottom of the fixed pallet 103 drives the rotating grinding wheel 104 to rotate below the fixed grinding wheel 102. The tablet medicine is put between the fixed grinding wheel 102 and the rotating grinding wheel 104 through the feeding cover 101. The rotating grinding wheel 104 rotates to grind the medicine into powder. The specific water in the solution storage tank 106 flows downward through the guide vertical pipe 107 and then through the shunt pipe 108 to the rotating grinding wheel 104. The water flow flushes the medicine powder on the rotating grinding wheel 104 and the fixed grinding wheel 102 and flows down through the slot on the side of the fixed pallet 103. The guide plate 204 guides the powder and water flow into the rotating cylinder 203. The solution is stored in the rotating cylinder 203. Part of the solution carries microorganisms and flows through the side filter holes into the collection cylinder 201. After the powder solution stands for a period of time, the drive motor at the bottom of the positioning carrier plate 2 drives the rotating cylinder 203 to rotate, so that the solution carrying microorganisms flows through the filter holes into the collection cylinder 201. The guide plate 202 guides the solution, and the solution carrying microorganisms flows into the collection cup 206. During the separation process, the cooling water flow in the refrigeration water tank 3 flows through the water outlet pipe 301 into the refrigeration pipe 302 to cool the collected solution. The water flow enters the circulation pipe 304 through the guide pipe 303. The circulation pipe 304 is located inside the grinding surface of the fixed grinding wheel 102 to cool the grinding position. The water flow flows back into the refrigeration water tank 3 through the return pipe 305 and is refrigerated again for recycling, ensuring that it will not be affected by temperature during the whole separation process.

[0035] In this article, the following points need to be noted:

[0036] 1. The attached drawings of the embodiments of this disclosure only relate to the structures involved in the embodiments of this disclosure. Other structures can refer to the general design.

[0037] 2. Without conflict, the embodiments of this disclosure and the features in the embodiments can be combined with each other to obtain new embodiments.

[0038] The above is only the specific implementation manner of this disclosure, but the protection scope of this disclosure is not limited thereto. Any person skilled in the art within the technical scope disclosed by this disclosure can easily think of changes or substitutions, which should be covered by the protection scope of this disclosure. Therefore, the protection scope of this disclosure should be subject to the protection scope of the claims.

Claims

1. A microbial separation device for tablet drugs, comprising: Separation housing (1), on both sides of the top of the separation housing (1), adjusting bolts are installed, and a fixed grinding wheel (102) is slidably installed on the inner top of the separation housing (1); characterized in that, on both sides of the top of the fixed grinding wheel (102), they are connected to the bottoms of the adjusting bolts on both sides of the top of the separation housing (1); on the inner bottom of the separation housing (1), a positioning carrier plate (2) is installed; at the middle position of the bottom of the positioning carrier plate (2), a driving motor is installed, and a discharge port is also opened at the bottom of the positioning carrier plate (2); on the top of the positioning carrier plate (2), a collection cylinder (201) is installed; the collection cylinder (201) is installed inside the separation housing (1), and a diversion nozzle is provided on the side of the collection cylinder (201), and the diversion nozzle penetrates through the outside of the separation housing (1); on the outside of the separation housing (1), a refrigeration water tank (3) is installed; on the top of the refrigeration water tank (3), a water pump is installed, and on the bottom of the refrigeration water tank (3), a water pump is installed, and a water outlet pipe (301) is installed on the output end of the water pump.

2. The microbial separation device for tablet drugs according to claim 1, wherein At the middle position of the top of the separation housing (1), a feed hood (101) is connected; inside the separation housing (1), a fixed support plate (103) is also installed; at the bottom of the fixed support plate (103), a servo motor is installed, and there are multiple slots on the side of the fixed support plate (103), and on the top of the fixed support plate (103), a rotating grinding wheel (104) is installed; the bottom of the rotating grinding wheel (104) is connected to the output end of the servo motor at the bottom of the fixed support plate (103), and the rotating grinding wheel (104) is rotatably installed below the fixed grinding wheel (102).

3. The microbial separation device for tablet drugs according to claim 2, characterized in that, On the top of the separation housing (1), a fixed bracket (105) is installed; on the top of the fixed bracket (105), a solution storage tank (106) is installed; at the bottom of the solution storage tank (106), a diversion vertical pipe (107) is installed; a control valve is installed on the diversion vertical pipe (107); inside the feed hood (101), a diversion pipe (108) is installed; at the bottom of the diversion pipe (108), water outlet holes are provided, and the diversion pipe (108) is connected to the bottom of the diversion vertical pipe (107).

4. The microbial separation device for tablet drugs according to claim 3, characterized in that, At the inner bottom of the collection cylinder (201), a diversion plate (202) is installed; at the middle position of the top of the positioning carrier plate (2), a rotating cylinder (203) is rotatably installed; on the side of the rotating cylinder (203), filter holes are provided, and the bottom of the rotating cylinder (203) is connected to the output end of the driving motor at the bottom of the positioning carrier plate (2), and the rotating cylinder (203) is rotatably installed inside the collection cylinder (201).

5. The microbial separation device for tablet drugs according to claim 4, characterized in that, Inside the separation housing (1), a guide plate (204) is installed; the guide plate (204) is below the fixed support plate (103) and above the rotating cylinder (203); at the outer bottom of the separation housing (1), a cup holder (205) is installed; on the cup holder (205), a collection cup (206) is placed; the collection cup (206) is below the diversion nozzle on the side of the collection cylinder (201).

6. The microbial separation device for tablet drugs according to claim 5, wherein, The bottom of the water outlet pipe (301) is installed with a refrigeration pipe (302) through the separation housing (1); the refrigeration pipe (302) is installed at the bottom of the positioning carrier plate (2), and a diversion pipe (303) is installed on the side of the refrigeration pipe (302); the diversion pipe (303) is installed inside the fixed grinding wheel (102) through the outside of the separation housing (1).

7. The microbial separation device for tablet drugs according to claim 6, wherein, A circulation pipe (304) is installed inside the fixed grinding wheel (102); one end of the circulation pipe (304) is connected to the diversion pipe (303), and the other end of the circulation pipe (304) is connected to a return pipe (305); the return pipe (305) passes through the separation housing (1) and is connected to the top of the refrigeration water tank (3).

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