Fluorescence immunoassay analyzer with suction head tray positioning structure
By using magnetic suction cups and air pump systems in fluorescence immunoassays, the problem of inaccurate positioning of the clamp seat and clamp plate is solved, achieving higher positioning accuracy and detection accuracy.
Patent Information
- Application Number
- CN202422286613.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-19
- Publication Date
- 2025-07-29
- Estimated Expiration
- 2034-09-19
AI Technical Summary
When used in existing fluorescence immunoassays, the clamping seat and clamping plate are difficult to effectively and symmetrically position due to different textures, resulting in inaccurate positioning.
The magnetic suction cup is arranged under the lower sleeve rod. Through the cooperation of the spring rod group, card and limit block, the power of the air pump is used to tighten the lower sleeve rod to achieve precise positioning.
It improves the adsorption tightness of the position, ensures the accuracy of positioning, and improves the accuracy of detection.
Smart Images

Figure CN223166757U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of fluorescence immunoassay analyzers, in particular to a fluorescence immunoassay analyzer with a pipette tip tray positioning structure. Background Art
[0002] A fluorescence immunoassay analyzer is an in vitro microanalysis instrument that uses non-radioactive isotope immunoassay technology. According to the characteristics of the fluorescence spectrum of the fluorescent label, by delaying the measurement time, the interference of non-specific fluorescence in the specimen is excluded to achieve the purpose of accurate quantitative analysis. Time-resolved fluorescence immunoassay analyzers are commonly used in the determination of proteins and polypeptide hormones, haptens, pathogen antigens and antibodies, tumor markers, dried blood spot samples, nucleic acids, and the activity of natural killer cells, etc.
[0003] When the existing fluorescence immunoassay analyzer is in use, for example, the application number CN202223147043.1 relates to the technical field of fluorescence immunoassay analyzers, specifically to a fluorescence immunoassay analyzer with a pipette tip tray positioning structure, including a base, a sliding box slidably arranged on the base, a pipette tip driving mechanism, and a fluorescence detection module; a positioning mechanism for limiting the position of the tray is arranged on the sliding box, and the positioning mechanism includes: a mounting seat connected above the sliding box; a centering positioning component arranged on the mounting seat to keep the tray in the middle position of the mounting seat; a clamping component arranged on the mounting seat to clamp the tray; however, in the above technology, the clamping seat and the clamping plate are difficult to effectively symmetrically position the product due to different textures. Therefore, the utility model proposes a fluorescence immunoassay analyzer with a pipette tip tray positioning structure to solve the problems existing in the prior art. Summary of the Utility Model
[0004] In view of the above problems, the utility model proposes a fluorescence immunoassay analyzer with a pipette tip tray positioning structure. The fluorescence immunoassay analyzer with a pipette tip tray positioning structure mainly uses a magnetic chuck arranged below the lower sleeve rod, inserts the lower sleeve rod into the side shell, and fixes the insertion plate with the cooperation of a spring rod group, a card, and a limiting block. After fixing the product, the magnetic chuck is effectively connected to the lower sleeve rod. Finally, the output power of an air pump enables the magnetic chuck to effectively suck and tighten the lower sleeve rod, thereby improving the tightness of position adsorption and ensuring the accuracy of the position.
[0005] To achieve the purpose of the utility model, the utility model is realized through the following technical solutions: A fluorescence immunoassay analyzer with a pipette tip tray positioning structure includes a base component and a positioning and detection mechanism. A clamping and transfer component assembled by bolts is arranged above one side of the base component, and a positioning and detection mechanism assembled by bolts is arranged on the top side of the base component;
[0006] The positioning and detecting mechanism includes a sleeve base, a side shell, a spring rod group, a card, a limiting block, a lower sleeve rod, a plug-in board, a magnetic suction cup, a connecting pipe, an air pump and a discharge port. The sleeve base is arranged on the top side of the middle part of the base assembly. A side shell is arranged above the sleeve base. A spring rod group is arranged at the inner end of the upper part of the side shell. A card is arranged at the inner end of the spring rod group. Limiting blocks are arranged on the outer sides of the four circumferences of the side shell. A lower sleeve rod is sleeved and installed on the inner side of the side shell. A plug-in board is arranged above the lower sleeve rod. A magnetic suction cup is arranged below the lower sleeve rod. A connecting pipe is arranged at the output end of the magnetic suction cup. An air pump is arranged at the output end of the connecting pipe. A discharge port is arranged at the output end of the air pump.
[0007] As a preferred embodiment of the present invention, the plug-in board has an array hole structure, and the side shell has an array groove structure.
[0008] As a preferred embodiment of the present invention, the base assembly includes a base block, a base plate, a plug-in base, a plug strip and a test tube body. A base plate is arranged on the top side of the base block. Plug-in bases are arranged above the two ends of the base plate. The plug-in bases are connected by plugging with plug strips. Array-distributed test tube bodies are plugged on the inner sides of the plug strips.
[0009] As a preferred embodiment of the present invention, the clamping and transferring component includes an upper frame, a sliding base, a driving motor, a worm, a slider, a cross arm, a lead screw, a threaded block, a pad base, a cylinder, a lifting frame and a mechanical clamp. The upper frame is bolted to the upper side of the edge of the base plate. A sliding base is arranged on the inner side of the upper frame by bolt assembly. A slider is slidably connected above the sliding base. A worm connected to the output end of the driving motor is threadedly connected to the inner side of the slider.
[0010] As a preferred embodiment of the present invention, a cross arm is arranged on the top side of the slider. A threaded block is threadedly connected to the cross arm through a lead screw. A pad base is arranged on the outer side of the threaded block by bolt assembly.
[0011] As a preferred embodiment of the present invention, a lifting frame connected to the output end of the cylinder is arranged below the pad base. A mechanical clamp is arranged below the lifting frame.
[0012] The beneficial effects of the present invention are:
[0013] The utility model mainly utilizes a magnetic chuck arranged below the lower sleeve rod, inserts the lower sleeve rod into the side shell, and fixes the insertion plate through the cooperation of a spring rod group, a card, and a limit block. After fixing the product, the magnetic chuck is effectively connected to the lower sleeve rod. Finally, the output power of an air pump enables the magnetic chuck to effectively suck and tighten the lower sleeve rod, thereby improving the adsorption tightness of the position and ensuring the position accuracy. Description of the Drawings
[0014] Figure 1 It is a three-dimensional structural schematic diagram of the utility model;
[0015] Figure 2 It is a bottom three-dimensional structural schematic diagram of the utility model;
[0016] Figure 3 It is a three-dimensional structural schematic diagram of the positioning and detecting mechanism of the utility model;
[0017] Figure 4 It is a three-dimensional structural schematic diagram of the air pump and the discharge port of the utility model.
[0018] Wherein: 1. Base assembly; 101. Base block; 102. Base plate; 103. Insertion base; 104. Insertion bar; 105. Test tube body; 2. Clamping and transferring component; 201. Upper frame; 202. Sliding base; 203. Driving motor; 204. Worm; 205. Slide block; 206. Cross arm; 207. Lead screw; 208. Threaded block; 209. Pad base; 2010. Cylinder; 2011. Lifting frame; 2012. Mechanical fixture; 3. Positioning and detecting mechanism; 301. Sleeve base; 302. Side shell; 303. Spring rod group; 304. Card; 305. Limit block; 306. Lower sleeve rod; 307. Insertion plate; 308. Magnetic chuck; 309. Connecting pipe; 3010. Air pump; 3011. Discharge port. Detailed Embodiment
[0019] To deepen the understanding of the utility model, the following will further elaborate on the utility model in combination with embodiments. These embodiments are only used to explain the utility model and do not constitute a limitation to the protection scope of the utility model.
[0020] According to Figures 1-4 As shown, this embodiment proposes a fluorescence immunoassay analyzer with a suction head tray positioning structure, including a base assembly 1 and a positioning and detecting mechanism 3. A clamping and transferring component 2 assembled by bolts is arranged above one side of the base assembly 1, and a positioning and detecting mechanism 3 assembled by bolts is arranged on the top side of the base assembly 1;
[0021] The positioning and detecting mechanism 3 includes a sleeve base 301, a side shell 302, a spring rod group 303, a card 304, a limit block 305, a lower sleeve rod 306, a plug-in board 307, a magnetic chuck 308, a connecting pipe 309, an air pump 3010 and a discharge port 3011. The sleeve base 301 is arranged on the middle top side of the base assembly 1. Above the sleeve base 301, there is a side shell 302. And inside the upper end of the side shell 302, there is a spring rod group 303. And inside the spring rod group 303, there is a card 304. On the outer sides of the four weeks of the side shell 302, there are limit blocks 305. On the inner side of the side shell 302, there is a lower sleeve rod 306 installed in a socket connection. And above the lower sleeve rod 306, there is a plug-in board 307. Below the lower sleeve rod 306, there is a magnetic chuck 308. And at the output end of the magnetic chuck 308, there is a connecting pipe 309. At the output end of the connecting pipe 309, there is an air pump 3010. And at the output end of the air pump 3010, there is a discharge port 3011.
[0022] The plug-in board 307 has an array hole-like structure, and the side shell 302 has an array groove-like structure.
[0023] In this embodiment, after the plug-in board 307 places the test tube body 105, the lower sleeve rod 306 and the plug-in board 307 are inserted into the side shell 302, so that the lower sleeve rod 306 is arranged on the top side of the magnetic chuck 308. And with the cooperation of the limit block 305, the spring rod group 303 and the card 304, the plug-in board 307 is inserted into the upper inner side of the side shell 302. And after the air pump 3010 outputs power to drive the output end to operate, with the cooperation of the magnetic chuck 308, the connecting pipe 309, the air pump 3010 and the discharge port 3011, the lower sleeve rod 306 can be effectively and tightly fixed on the top side of the magnetic chuck 308, so as to facilitate effective detection and use.
[0024] The base assembly 1 includes a base block 101, a base plate 102, a plug-in base 103, a plug bar 104 and a test tube body 105. On the top side of the base block 101, there is a base plate 102. And above the two ends of the base plate 102, there are plug-in bases 103. The plug-in bases 103 are connected by plug bars 104. And on the inner side of the plug bars 104, there are test tube bodies 105 distributed in an array.
[0025] In this embodiment, when in use, the device is placed at the processing location through the base block 101 and the base plate 102. Through the base plate 102, the clamping and transferring component 2 and the positioning and detecting mechanism 3 are assembled and connected. And the plug bars 104 and the test tube bodies 105 are inserted and fixed on the plug-in bases 103.
[0026] The clamping and transferring component 2 includes an upper frame 201, a sliding base 202, a driving motor 203, a worm 204, a slider 205, a cross arm 206, a lead screw 207, a threaded block 208, a pad base 209, a cylinder 2010, a lifting frame 2011, and a mechanical fixture 2012. The upper frame 201 is bolted above the side of the base plate 102. A bolt-assembled sliding base 202 is provided on the inner side of the upper frame 201, and a slidably connected slider 205 is provided above the sliding base 202. The inner side of the slider 205 is threadedly connected to a worm 204 that connects to the output end of the driving motor 203.
[0027] In this embodiment, when in use, the driving motor 203 outputs power to drive the operation of its output end. When the driving motor 203 outputs power and can drive the worm 204 on the upper frame 201 to rotate helically, the cross arm 206 is moved to a suitable position under the action of the slider 205 and the sliding base 202.
[0028] The top side of the slider 205 is provided with a cross arm 206, and a threaded block 208 is threadedly connected to the cross arm 206 through a lead screw 207. A bolt-assembled pad base 209 is provided on the outer side of the threaded block 208.
[0029] In this embodiment, after the cross arm 206 is moved to a suitable position, the output end on the cross arm 206 outputs power to drive the operation of its output end. Then, the lead screw 207 on the cross arm 206 rotates helically, and the threaded block 208 moves the pad base 209 to a suitable position.
[0030] A lifting frame 2011 connected to the output end of the cylinder 2010 is provided below the pad base 209, and a mechanical fixture 2012 is provided below the lifting frame 2011.
[0031] In this embodiment, after the pad base 209 is moved to a suitable position, the output end of the cylinder 2010 outputs power to drive the operation of the output end of the cylinder 2010, which can drive the lifting frame 2011 to drive the mechanical fixture 2012 to descend to a suitable position to move the test tube body 105 on the plug-in base 103, and then move the test tube body 105 to the plug-in board 307.
[0032] The working principle of the fluorescence immunoassay analyzer with a tip tray positioning structure is as follows: When in use, the device is placed at the processing location through the base block 101 and the base plate 102. The clamping and transfer component 2 and the positioning and detection mechanism 3 are assembled and connected through the base plate 102. The insert 104 and the test tube body 105 are inserted and fixed on the insertion base 103. When in need of use, the driving motor 203 outputs power to drive the output end to operate. When the driving motor 203 outputs power to drive the worm 204 on the upper frame 201 to spiral and run, the cross arm 206 is run to a suitable position under the action of the slider 205 and the sliding base 202. After the cross arm 206 runs to a suitable position, the output end on the cross arm 206 outputs power to drive the output end to operate, and then the lead screw 207 on the cross arm 206 spirally runs, so that the threaded block 208 runs the pad base 209 to a suitable position. After the pad base 209 runs to a suitable position, the output end of the cylinder 2010 outputs power to drive the output end of the cylinder 2010 to operate, and then drives the lifting frame 2011 to drive the mechanical fixture 2012 to descend to a suitable position to run the test tube body 105 on the insertion base 103, so that the test tube body 105 runs onto the insertion plate 307. After the insertion plate 307 places the test tube body 105, the lower sleeve rod 306 and the insertion plate 307 are inserted into the side shell 302. The lower sleeve rod 306 is arranged on the top side of the magnetic chuck 308. The limiting block 305, the spring rod group 303 and the card 304 cooperate to insert the insertion plate 307 into the upper inner side of the side shell 302. The air pump 3010 outputs power to drive the output end to operate, and then under the joint cooperation of the magnetic chuck 308, the connecting pipe 309, the air pump 3010 and the drain port 3011, the lower sleeve rod 306 can be effectively and tightly fixed on the top side of the magnetic chuck 308 for effective detection and use.
[0033] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited by the above embodiments. What is described in the above embodiments and the specification only illustrates the principle of the present invention. Without departing from the spirit and scope of the present invention, the present invention will have various changes and improvements, and these changes and improvements all fall within the scope of the present invention claimed. The scope of protection claimed by the present invention is defined by the appended claims and their equivalents.
Claims
1. A fluorescence immunoassay analyzer with a pipette tip tray positioning structure, comprising a base assembly (1) and a positioning and detection mechanism (3), characterized in that: Above one side of the base assembly (1), a clamping and transferring component (2) assembled by bolts is provided, and a positioning and detecting mechanism (3) assembled by bolts is provided on the top side of the base assembly (1); The positioning and detecting mechanism (3) includes a sleeve base (301), a side shell (302), a spring rod group (303), a card (304), a limiting block (305), a lower sleeve rod (306), a plug-in board (307), a magnetic chuck (308), a connecting pipe (309), an air pump (3010) and a discharge port (3011). The sleeve base (301) is arranged on the middle top side of the base assembly (1). A side shell (302) is arranged above the sleeve base (301). A spring rod group (303) is arranged at the upper inner end of the side shell (302), and a card (304) is arranged at the inner end of the spring rod group (303). Limiting blocks (305) are arranged on the outer sides of the four weeks of the side shell (302). A lower sleeve rod (306) is sleeved and installed on the inner side of the side shell (302). A plug-in board (307) is arranged above the lower sleeve rod (306). A magnetic chuck (308) is arranged below the lower sleeve rod (306). The output end of the magnetic chuck (308) is provided with a connecting pipe (309). The output end of the connecting pipe (309) is provided with an air pump (3010). The output end of the air pump (3010) is provided with a discharge port (3011).
2. The fluorescence immunoassay analyzer with a tip tray positioning structure according to claim 1, wherein: The plug-in board (307) has an array hole structure, and the side shell (302) has an array groove structure.
3. The fluorescence immunoassay analyzer with a tip tray positioning structure according to claim 1, wherein: The base assembly (1) includes a base block (101), a base plate (102), a plug-in base (103), a plug-in strip (104) and a test tube body (105). A base plate (102) is arranged on the top side of the base block (101). Plug-in bases (103) are arranged above both ends of the base plate (102). The plug-in bases (103) are connected by plugging with plug-in strips (104). The inner sides of the plug-in strips (104) are plugged with an array of test tube bodies (105).
4. A fluorescence immunoassay analyzer with a tip tray positioning structure according to claim 3, characterized in that: The clamping and transferring component (2) includes an upper frame (201), a sliding base (202), a driving motor (203), a worm (204), a slider (205), a cross arm (206), a lead screw (207), a threaded block (208), a pad base (209), a cylinder (2010), a lifting frame (2011) and a mechanical clamp (2012). The upper frame (201) is bolted to the upper side of the edge of the base plate (102). A sliding base (202) assembled by bolts is arranged on the inner side of the upper frame (201). A slider (205) connected by sliding is arranged above the sliding base (202). A worm (204) connecting the output end of a connecting driving motor (203) is threadedly connected to the inner side of the slider (205).
5. The fluorescence immunoassay analyzer with a pipette tip tray positioning structure according to claim 4, characterized in that: A cross arm (206) is provided on the top side of the slider (205), and a threaded block (208) is threadedly connected to the cross arm (206) through a lead screw (207). A pad base (209) assembled with bolts is provided on the outer side of the threaded block (208).
6. The fluorescence immunoassay analyzer with a pipette tip tray positioning structure according to claim 4, wherein: A lifting frame (2011) connecting to the output end of a connecting cylinder (2010) is provided below the pad base (209), and a mechanical fixture (2012) is provided below the lifting frame (2011).
Citation Information
Patent Citations
Fluorescence immunoassay analyzer with suction head tray positioning structure
CN219224810U