Sample detection device

Abstract

The utility model relates to a sample detection device. The sample detection device comprises a detection tube, a test strip, a sampling piece and a base, wherein an accommodating cavity is formed in the detection tube, and a window is arranged on the tube wall of the detection tube; the test strip is arranged in the accommodating cavity; the sampling piece comprises a main body and a sampling head connected with the main body, the main body is connected to the bottom end of the detection tube, a liquid inlet hole is formed in the outer side circumferential surface of the main body and communicated with the containing cavity, the sampling head is located on the side, away from the detection tube, of the main body, and a liquid suction channel is formed in the sampling head and used for sucking sample liquid; the base is provided with a mixing cavity used for being filled with diluent, the mixing cavity is used for allowing the sampling piece to be inserted, when the sampling piece is inserted into the mixing cavity, the liquid inlet hole is located in the mixing cavity, the diluent in the mixing cavity can be mixed with sample liquid in the liquid suction channel to form liquid to be detected, and the liquid level of the liquid to be detected in the mixing cavity rises and then reaches the liquid inlet hole. The to-be-detected liquid is extruded into the accommodating cavity through the liquid inlet hole and is absorbed by the test strip.

Description

Technical Field

[0001] The utility model relates to the technical field of in vitro immunodiagnosis, and particularly to a sample detection device. Background Art

[0002] Immunochromatographic detection technology is a new immunodetection technology that emerged in the 1990s. Its characteristics are the application of antigen-antibody immunological reactions and chromatographic reactions, and in the form of a dry-strip test paper to achieve the purpose of quickly and accurately detecting the analyte. At the same time, immunochromatographic technology is also an important means for point-of-care testing (POCT). The basis of this detection is established on the principle of specific binding between immune molecules, and it can detect whether the specific antigen or antibody to be detected is contained in the sample to be tested. Immunochromatographic technology can quickly and conveniently provide reliable test results for samples.

[0003] In the field of in vitro immunodiagnosis by immunochromatography, there are two common liquid sample detection methods:

[0004] One is to collect the sample using a liquid sample collection container, then mix it with a sample diluent, and drop the diluted sample onto the test strip. After waiting for a certain time, the test result is read.

[0005] The other is to directly drop the liquid sample onto the designated position of the test strip, then drop the sample diluent to complete the detection, or use the sample to directly infiltrate the sample pad end of the test strip to complete sample loading and detection.

[0006] However, these common detection methods will cause the sample to be tested to be exposed to the air for a long time, which not only affects the detection accuracy of the sample to be tested, but also may cause secondary contamination to the testing personnel if the pathogen to be detected is a pathogenic bacterium or virus.

[0007] The above information disclosed in the background art of the present utility model is only used to understand the background of the concept of the present utility model and may include information that does not constitute the prior art. Summary of the Utility Model

[0008] Based on this, it is necessary to provide a sample detection device for the above problems.

[0009] A sample detection device, comprising:

[0010] A test tube, in which a receiving cavity is formed, and a viewing window is provided on the tube wall of the test tube;

[0011] A test strip, which is arranged in the receiving cavity;

[0012] Sampling piece, the sampling piece includes a main body and a sampling head connected to the main body. The main body is connected to the bottom end of the test tube. Liquid inlet holes are formed on the outer circumferential surface of the main body, and the liquid inlet holes communicate with the accommodating cavity. The sampling head is located on the side of the main body away from the test tube. A liquid suction channel is formed in the sampling head, and the liquid suction channel is used to suck the sample liquid;

[0013] Base, a mixing cavity for filling the diluent is provided on the base. The mixing cavity is used for the sampling piece to be inserted. When the sampling piece is inserted into the mixing cavity, the liquid inlet holes are located in the mixing cavity. The diluent in the mixing cavity can be mixed with the sample liquid in the liquid suction channel to form a liquid to be detected, and the liquid level of the liquid to be detected in the mixing cavity rises and reaches the liquid inlet holes, so as to squeeze the liquid to be detected into the accommodating cavity through the liquid inlet holes and be absorbed by the test strip.

[0014] The above sample detection device of the present utility model can at least achieve the following beneficial effects: First, the lower end of the sampling head of the sampling piece can be used to contact sample liquids such as serum, plasma, whole blood, fingertip blood, and urine first, and the liquid suction channel of the sampling head can quantitatively inhale the sample liquid to complete sample collection. Then, the sampling piece with the collected sample liquid can be inserted into the mixing cavity of the base, and the sample liquid in the sampling head can be fully mixed with the diluent in the mixing cavity to form a liquid to be detected. As the sampling piece is pressed down, most of the space in the mixing cavity is occupied by the sampling piece entering it, so the liquid level of the liquid to be detected in the mixing cavity will be squeezed into the accommodating cavity through the liquid inlet holes, and the test strip in the accommodating cavity can absorb the liquid to be detected and complete the detection. The detection result can be observed from the window on the test tube. It should be emphasized that after the sample is collected and the sampling piece is inserted into the mixing cavity of the base in this application, the sample liquid, diluent, and liquid to be detected are in a relatively sealed environment during the subsequent whole detection process, and the sample is not easily in contact with air, which can not only avoid affecting the sample quality, but also avoid sample spillage and pollution. In addition, in the traditional method, after the sample is initially collected, the tester still needs to mix the sample liquid and the diluent to form a liquid to be detected, and the tester also needs to drop the liquid to be detected onto the test paper. The steps are numerous, the operation is cumbersome, and the time consumed is long; while the detection steps of this sample detection device of the present utility model are fewer. After collecting the sample, only the sampling piece needs to be inserted onto the base. The operation steps and the time consumed are less, reducing the learning cost of the user, making the whole detection process more controllable, the detection success rate higher, and the safety of the product higher than that of traditional detection products.

[0015] In one embodiment, a sealing piece for sealing the insertion opening of the mixing chamber is further provided on the base, and the sealing piece is arranged to be pierced by the sampling head when the sampling head is to be inserted into the mixing chamber. In other words, a diluent can be pre-placed in the mixing chamber of the base, and then the insertion opening of the mixing chamber is sealed with the sealing piece, which can not only prevent the diluent in the mixing chamber from flowing out, but also form a good sealing environment to ensure the quality and long-term effectiveness of the diluent.

[0016] In one embodiment, the outer contour of the cross-section of the sampling head is smaller than the outer contour of the cross-section of the main body. The mixing chamber includes a first hole section and a second hole section communicating with the first hole section. The insertion opening is formed on one side of the second hole section far from the first hole section. The first hole section is adapted to the sampling head, and the second hole section is adapted to the main body. Such a structural setting means that after the sampling member extends into the mixing chamber from the insertion opening, the sampling head with a smaller size is inserted into the deeper first hole section, and the main body with a larger size is inserted into the shallower second hole section. That is, the longitudinal section of the mixing chamber is generally distributed in a stepped hole shape. Such a structural setting can make the connection between the sampling member and the mixing chamber more stable and reliable, thereby ensuring the normal progress of the detection.

[0017] In one embodiment, the liquid suction channel is a capillary channel. The working principle of the capillary channel is mainly based on the cohesive force, adhesive force and surface tension of liquid molecules. When the capillary channel end of the sampling head contacts a sample liquid such as plasma, the sample liquid can enter the capillary channel with the assistance of the above various forces, thus completing the sample collection.

[0018] In one embodiment, the sealing piece is an aluminum foil. Aluminum foil is light in weight, low in cost and good in sealing effect.

[0019] In one embodiment, the base includes a base body and a convex platform provided on the top surface of the base body. The mixing chamber is formed in the convex platform, and the insertion opening is provided on the side of the convex platform facing away from the base body.

[0020] In one embodiment, the base further includes an upper cover. The upper cover is covered on the top surface of the base body, and an opening is provided in the upper cover. The opening is aligned with the insertion opening and is used for the sampling head to pass through to pierce the sealing piece and extend into the mixing chamber through the insertion opening.

[0021] In one embodiment, at least a part of the inner surface of the upper cover is sleeved on the outer circumferential surface of the base body. A clamping convex portion is provided on either the outer circumferential surface of the base body or the inner surface of the upper cover, and a clamping concave portion is provided on the other of the outer circumferential surface of the base body and the inner surface of the upper cover. The upper cover is clamped with the base body through the cooperation of the clamping convex portion and the clamping concave portion.

[0022] In one embodiment, the upper cover and the base body are integrally provided.

[0023] In one embodiment, the inner surface of one end of the mixing chamber close to the insertion port is in sealing contact with the outer surface of the main body of the sampling member. Such a structural arrangement can achieve sealing by using the sampling member to closely adhere to the inner wall of the insertion port after the sampling member is inserted into the mixing chamber, which is beneficial to reducing the contact between the liquid in the mixing chamber and the outside atmosphere.

[0024] In one embodiment, the test tube includes a tube body and a test strip support. An accommodation cavity is formed in the tube body. A window for observing the test strip is provided on the tube wall of the tube body. The test strip support includes an end cap and a support connected to the end cap. The end cap is hermetically covered on the top of the tube body. The sampling head is connected to the bottom of the tube body. A card slot for placing the test strip is formed on the support. During assembly, the test strip can be first placed in the card slot of the support, and then the support is inserted into the accommodation cavity of the tube body. The end cap at the end of the support is hermetically covered on the top end of the tube body.

[0025] In one embodiment, the card slot is adapted to the test strip.

[0026] In one embodiment, a sealing protrusion is formed on one side of the end cap close to the tube body. The sealing protrusion is embedded in the accommodation cavity at the top end of the tube body and is in sealing contact with the inner surface of the accommodation cavity. The sealing protrusion can achieve sealing and fixation through interference fit with the inner surface of the accommodation cavity at the top end of the tube body.

[0027] In one embodiment, the number of the liquid inlet holes is set to be multiple, and the multiple liquid inlet holes are circumferentially spaced apart along the main body of the sampling member. Appropriately increasing the number of the liquid inlet holes, such as respectively opening a liquid inlet hole on both sides of the main body of the sampling member, can improve the liquid inlet speed of the liquid inlet holes, enable the liquid to be detected to enter the accommodation cavity faster and be absorbed by the test strip, thereby improving the detection speed.

[0028] In one embodiment, the test strip includes an absorption pad with a water absorption function, a nitrocellulose membrane coated with a detection line and a quality control line, a conjugate pad coated with a labeled protein conjugate, and a sample pad for absorbing the liquid to be detected, which are sequentially connected along the extension direction of its own length. One end of the test strip provided with the sample pad is close to the liquid inlet hole. After the liquid to be detected enters the accommodation cavity from the liquid inlet hole and contacts the test strip, the liquid to be detected can chromatograph upward along the reagent strip under capillary action, and the detection result is displayed at the positions of the quality control line and the detection line of the nitrocellulose membrane, and the quality control line and the detection line of the nitrocellulose membrane can be observed through the window. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings required for the description of the embodiments or the prior art. Obviously, the drawings in the following description are only some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can be obtained based on these drawings.

[0030] Figure 1 A schematic structural view of a test strip holder of a sample detection device provided by an embodiment of the present invention.

[0031] Figure 2 A schematic structural view of a test strip of a sample detection device provided by an embodiment of the present invention.

[0032] Figure 3 A schematic structural view of a tube body of a detection tube of a sample detection device provided by an embodiment of the present invention.

[0033] Figure 4 A schematic structural view of a sampling member of a sample detection device provided by an embodiment of the present invention.

[0034] Figure 5 A cross-sectional view of a test strip holder of a sample detection device provided by an embodiment of the present invention.

[0035] Figure 6 A schematic structural view of a base of a sample detection device provided by an embodiment of the present invention.

[0036] Figure 7 A schematic structural view of an upper cover of a sample detection device provided by an embodiment of the present invention.

[0037] Figure 8 A cross-sectional view of a base of a sample detection device provided by an embodiment of the present invention.

[0038] Figure 9 A partial cross-sectional view of a sample detection device provided by an embodiment of the present invention, wherein the sampling member has punctured the seal and inserted into the mixing cavity of the base.

[0039] Reference numerals:

[0040] 100, Detection tube; 110, Tube body; 111, Accommodation cavity; 112, Window; 120, Test strip holder; 130, End cap; 131, Sealing projection; 200, Test strip; 210, Absorbent pad; 220, Nitrocellulose membrane; 221, Detection line; 222, Quality control line; 230, Protein conjugate pad; 240, Sample pad; 300, Sampling member; 310, Main body; 311, Liquid inlet hole; 320, Sampling head; 321, Liquid absorption channel; 400, Base; 410, Base body; 420, Boss; 430, Mixing cavity; 431, First hole section; 432, Second hole section; 433, Insertion port; 440, Clamping projection; 500, Sealing sheet; 600, Upper cover; 610, Opening; 620, Clamping recess. Detailed implementation manners

[0041] To make the above objects, features, and advantages of the present utility model more apparent and understandable, the following will describe the detailed implementation manners of the present utility model with reference to the accompanying drawings. Many specific details are set forth in the following description to fully understand the present utility model. However, the present utility model can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without departing from the connotation of the present utility model. Therefore, the present utility model is not limited by the specific embodiments disclosed below.

[0042] Please refer to Figures 1 to 9 , in some implementation manners, the present utility model provides a sample detection device, which includes a detection tube 100, a test strip 200, a sampling member 300, and a base 400. Among them, an accommodation cavity 111 is formed inside the detection tube 100, and a window 112 is provided on the tube wall of the detection tube 100; the test strip 200 is disposed inside the accommodation cavity 111; the sampling member 300 includes a main body 310 and a sampling head 320 connected to the main body 310, the main body 310 is connected to the bottom end of the detection tube 100, a liquid inlet hole 311 is formed on the outer circumferential surface of the main body 310, the liquid inlet hole 311 communicates with the accommodation cavity 111, the sampling head 320 is located on the side of the main body 310 away from the detection tube 100, and a liquid absorption channel 321 is formed inside the sampling head 320 for sucking sample liquid; a mixing cavity 430 for filling dilution liquid is provided on the base 400, and the mixing cavity 430 is used for the sampling member 300 to be detachably inserted; as Figure 9As shown, when the sampling member 300 is inserted into the mixing chamber 430, the liquid inlet hole 311 is located within the mixing chamber 430. The diluent within the mixing chamber 430 can mix with the sample liquid within the liquid suction channel 321 to form a liquid to be detected, and cause the liquid level of the liquid to be detected within the mixing chamber 430 to rise until it reaches the liquid inlet hole 311, so as to squeeze the liquid to be detected through the liquid inlet hole 311 into the accommodating chamber 111 and be absorbed by the test strip 200.

[0043] The above-described sample detection device of the present utility model can at least achieve the following beneficial effects: First, the lower end of the sampling head 320 of the sampling member 300 can be used to contact sample liquids such as serum, plasma, whole blood, fingertip blood, urine, etc., and a part of the sample liquid can be inhaled through the liquid suction channel 321 of the sampling head 320 to complete sample collection. Then, the sampling member 300 with the collected sample liquid can be inserted into the mixing chamber 430 of the base 400, and the sample liquid within the sampling head 320 can be fully mixed with the diluent within the mixing chamber 430. As the sampling member 300 is pressed down, most of the space within the mixing chamber 430 is occupied by the sampling member 300 that enters it, then the liquid of the liquid to be detected within the mixing chamber 430 will pass through the liquid inlet hole 311, and the liquid to be detected can be squeezed from the liquid inlet hole 311 into the accommodating chamber 111, and the test strip 200 within the accommodating chamber 111 can absorb the liquid to be detected and complete the detection, and the detection result can be observed through the window 112 on the test tube 100. It should be emphasized that after the present application completes sample collection and inserts the sampling member 300 into the mixing chamber 430 of the base 400, the sample liquid, diluent, and liquid to be detected are in a relatively sealed environment throughout the subsequent detection process, and the sample is not easily in contact with air, which can not only avoid affecting the sample quality but also avoid sample leakage and contamination. In addition, in the traditional method, after the initial sample collection is completed, the tester still needs to mix the sample liquid with the diluent to form a liquid to be detected, and also needs the tester to drop the liquid to be detected onto the test paper. The steps are numerous, the operation is cumbersome, and the time consumed is long; while the detection steps of this sample detection device of the present utility model are fewer. After collecting the sample, it only needs to insert the sampling member 300 onto the base 400. The operation steps and the time consumed are less, reducing the learning cost of the user, making the entire detection process more controllable, the detection success rate higher, and the safety of the product higher compared to traditional detection products.

[0044] Specifically, as Figure 8As shown, in some of the embodiments, a sealing piece 500 for sealing the insertion opening 433 of the mixing chamber 430 is further provided on the base 400. The sealing piece 500 is arranged to be pierced by the sampling head 320 when the sampling head 320 is to be inserted into the mixing chamber 430. In other words, a diluent can be pre-placed in the mixing chamber 430 of the base 400, and then the insertion opening 433 of the mixing chamber 430 is sealed with the sealing piece 500, which can not only prevent the diluent in the mixing chamber 430 from flowing out, but also form a good sealing environment to ensure the quality and long-term effectiveness of the diluent.

[0045] Specifically, as Figure 4 , Figure 5 , Figure 8 and Figure 9 shown, in some of the embodiments, the outer contour of the cross-section of the sampling head 320 is smaller than the outer contour of the cross-section of the main body 310. The mixing chamber 430 includes a first hole section 431 and a second hole section 432 communicating with the first hole section 431. The insertion opening 433 is formed on one side of the second hole section 432 away from the first hole section 431. The first hole section 431 is adapted to the sampling head 320, and the second hole section 432 is adapted to the main body 310. Such a structural setting means that after the sampling member 300 extends into the mixing chamber 430 from the insertion opening 433, the smaller-sized sampling head 320 is inserted into the deeper first hole section 431, and the larger-sized main body 310 is inserted into the shallower second hole section 432. That is, the longitudinal section of the mixing chamber 430 is generally distributed in a stepped hole shape. Such a structural setting can make the connection between the sampling member 300 and the mixing chamber 430 more stable and reliable, thereby ensuring the normal progress of the detection.

[0046] Specifically, in some of the embodiments, the sealing piece 500 is an aluminum foil. The aluminum foil is light in weight, low in cost and good in sealing effect.

[0047] Specifically, in some of the embodiments, the liquid absorption channel 321 is a capillary channel. The working principle of the capillary channel is mainly based on the cohesive force, adhesive force and surface tension of liquid molecules. When the capillary channel end of the sampling head 320 contacts a sample liquid such as plasma, the sample liquid can enter the capillary channel with the assistance of the above various acting forces, thereby completing the sample collection.

[0048] Please refer to Figure 6 and Figure 8 [[ID=2--4]]4, in some of the embodiments, the base 400 includes a seat body 410 and a boss 420 provided on the top surface of the seat body 410. The mixing chamber 430 is formed in the boss 420, and the insertion opening 433 is provided on the side of the boss 420 facing away from the seat body ^{-}

[0049] Further, asFigure 7 and Figure 9 As shown in Figure 9 , in some embodiments, the base 400 further includes an upper cover 600. The upper cover 600 covers the top surface of the base body 410, and an opening 610 is formed in the upper cover 600. The opening 610 is aligned with the insertion port 433, and is used for the sampling head 320 to pass through to pierce the sealing sheet 500 and extend into the mixing chamber 430 through the insertion port 433.

[0050] Furthermore, as shown in Figure 6 , Figure 7 and Figure 9 , in some embodiments, at least a part of the inner surface of the upper cover 600 is sleeved on the outer circumferential surface of the base body 410. A clamping convex portion 440 is provided on either the outer circumferential surface of the base body 410 or the inner surface of the upper cover 600, and a clamping concave portion 620 is provided on the other of the outer circumferential surface of the base body 410 and the inner surface of the upper cover 600. The upper cover 600 is clamped to the base body 410 by the cooperation of the clamping convex portion 440 and the clamping concave portion 620.

[0051] Furthermore, in some embodiments, the inner surface of the mixing chamber 430 near one end of the insertion port 433 is in sealing contact with the outer surface of the main body 310 of the sampling member 300. Such a structural arrangement can achieve sealing by using the sampling member 300 to closely adhere to the inner wall of the insertion port 433 after the sampling member 300 is inserted into the mixing chamber 430, which is beneficial to reducing the contact between the liquid in the mixing chamber 430 and the outside atmosphere.

[0052] In other embodiments, the upper cover 600 and the base body 410 may also be integrally provided.

[0053] Please refer to Figure 1 , Figure 2 and Figure 3 , in some embodiments, the test tube 100 includes a tube body 110 and a test strip holder 120. An accommodation chamber 111 is formed in the tube body 110, and a viewing window 112 for observing the test strip 200 is provided on the tube wall of the tube body 110. The test strip holder 120 includes an end cap 130 and a bracket connected to the end cap 130. The end cap 130 seals and covers the top of the tube body 110. The sampling head 320 is connected to the bottom of the tube body 110, and a card slot for placing the test strip 200 is formed on the bracket. In some embodiments, the card slot is adapted to the test strip 200. During assembly, the test strip 200 can be first placed into the card slot of the bracket, and then the bracket is inserted into the accommodation chamber 111 of the tube body 110, and the end cap 130 at the end of the bracket seals and covers the top of the tube body 110.

[0054] Specifically, as Figure 1 shown, in some of the embodiments, a sealing protrusion 131 is formed on one side of the end cap 130 close to the tube body 110, and the sealing protrusion 131 is embedded in the accommodation cavity 111 at the top end of the tube body 110 and is in sealing contact with the inner surface of the accommodation cavity 111. The sealing protrusion 131 can achieve sealing and fixation through interference fit with the inner surface of the accommodation cavity 111 at the top end of the tube body 110.

[0055] Specifically, as Figure 3 and Figure 4 shown, in some of the embodiments, the main body 310 of the sampling member 300 is detachably sleeved on the outer circumferential surface of the bottom of the test tube 100. Such a structural setting means that the sampling member 300 can be disassembled from the test tube 100, and the parts can be manufactured more conveniently.

[0056] Furthermore, as Figure 5 and Figure 9 shown, in some of the embodiments, the number of the liquid inlet holes 311 is set to be multiple, and the multiple liquid inlet holes 311 are circumferentially spaced apart along the main body 310 of the sampling member 300. Appropriately increasing the number of the liquid inlet holes 311, as Figure 5 shown, by respectively opening a liquid inlet hole 311 on both sides of the main body 310 of the sampling member 300, the liquid inlet speed of the liquid inlet holes 311 can be increased, so that the liquid to be detected can enter the accommodation cavity 111 faster and be absorbed by the test strip 200, thereby improving the detection speed.

[0057] Please refer to Figure 2 , in some of the embodiments, the test strip 200 includes an absorption pad 210 with a water absorption function, a nitrocellulose membrane 220 coated with a detection line 221 and a quality control line 222, a conjugate pad 230 coated with a labeled protein conjugate, and a sample pad 240 for absorbing the liquid to be detected, which are sequentially connected along the extending direction of its own length. One end of the test strip 200 provided with the sample pad 240 is close to the liquid inlet hole 311. After the liquid to be detected enters the accommodation cavity 111 from the liquid inlet hole 311 and contacts the test strip 200, the liquid to be detected can chromatograph upward along the reagent strip under the capillary action, and the detection result is shown at the positions of the quality control line 222 and the detection line 221 of the nitrocellulose membrane 220, and the quality control line 222 and the detection line 221 of the nitrocellulose membrane 220 can be observed through the viewing window 112. Among them, the viewing window 112 can be obtained by directly opening a hole in the tube wall of the tube body 110, or by embedding a transparent sheet in the tube wall of the tube body 110.

[0058] The technical features of the above-described embodiments can be combined arbitrarily. For the sake of brevity of description, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, it should be considered as falling within the scope described in this specification.

[0059] The above-described embodiments merely represent several implementation manners of the present utility model. The description thereof is relatively specific and detailed, but it should not be construed as a limitation on the scope of the patent application. It should be noted that for those of ordinary skill in the art, without departing from the concept of the present utility model, several modifications and improvements can still be made, and all of these belong to the protection scope of the present utility model. Therefore, the protection scope of the patent of the present utility model shall be subject to the appended claims.

[0060] In the description of the present utility model, it should be understood that if such terms as "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. appear, the orientation or positional relationship indicated by these terms is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation on the present utility model.

[0061] In addition, if such terms as "first" and "second" appear, these terms are only used for descriptive purposes and should not be construed as indicating or implying relative importance or implicitly specifying the quantity of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include at least one such feature. In the description of the present utility model, if the term "plurality" appears, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise specifically and clearly defined.

[0062] In the present utility model, unless otherwise clearly specified and limited, if such terms as "installation", "connection", "connection", "fixation", etc. appear, these terms should be understood in a broad sense. For example, it may be a fixed connection, a detachable connection, or integrated; it may be a mechanical connection or an electrical connection; it may be directly connected or indirectly connected through an intermediate medium, and it may be the communication inside two elements or the interaction relationship between two elements, unless otherwise clearly limited. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific circumstances.

[0063] In the present utility model, unless otherwise clearly defined and limited, when a first feature is described as being "on" or "under" a second feature or the like, it may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, the first feature being "above", "over" and "on top of" the second feature may mean that the first feature is directly above or obliquely above the second feature, or merely indicates that the first feature has a higher horizontal height than the second feature. The first feature being "under", "below" and "beneath" the second feature may be that the first feature is directly below or obliquely below the second feature, or merely indicates that the first feature has a lower horizontal height than the second feature.

[0064] [[ID=З]]It should be noted that if an element is referred to as being "fixed to" or "disposed on" another element, it can be directly on the other element or there may also be an intermediate element. If an element is considered to be "connected to" another element, it can be directly connected to the other element or there may be an intermediate element at the same time. If so, the terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used in the present utility model are only for the purpose of illustration and do not represent the only implementation.

[0065] In the description of this specification, the description with reference to terms such as "an embodiment", "other embodiments" etc. means that the specific features, structures, materials or features described in connection with the embodiment or example are included in at least one embodiment or example of the present utility model. In this specification, the schematic description of the above terms does not necessarily refer to the same embodiment or example. Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the technical field to which the present utility model belongs. The terms used in the specification of the present utility model herein are only for the purpose of describing specific embodiments and are not intended to limit the present utility model.

Claims

1. A sample detection device, characterized in that, Comprising: A detection tube, an accommodation cavity is formed inside the detection tube, and a viewing window is provided on the tube wall of the detection tube; A test strip, which is arranged in the accommodation cavity; A sampling member, the sampling member includes a main body and a sampling head connected to the main body, the main body is connected to the bottom end of the detection tube, a liquid inlet hole is formed on the outer circumferential surface of the main body, the liquid inlet hole communicates with the accommodation cavity, the sampling head is located on the side of the main body away from the detection tube, and a liquid absorption channel is formed in the sampling head, and the liquid absorption channel is used for sucking sample liquid; A base, a mixing cavity for filling a diluent is provided on the base, the mixing cavity is for inserting the sampling member, when the sampling member is inserted into the mixing cavity, the liquid inlet hole is located in the mixing cavity, and the diluent in the mixing cavity can be mixed with the sample liquid in the liquid absorption channel to form a liquid to be detected, and the liquid level of the liquid to be detected in the mixing cavity rises to reach the liquid inlet hole, so as to squeeze the liquid to be detected into the accommodation cavity through the liquid inlet hole and be absorbed by the test strip.

2. The sample detection device according to claim 1, wherein A sealing piece for sealing the insertion opening of the mixing cavity is further provided on the base, and the sealing piece is arranged to be pierced by the sampling head when the sampling head is to be inserted into the mixing cavity.

3. The sample detection device according to claim 2, wherein The outer contour of the cross section of the sampling head is smaller than the outer contour of the cross section of the main body, the mixing cavity includes a first hole section and a second hole section communicating with the first hole section, the insertion opening is formed on the side of the second hole section away from the first hole section, the first hole section is adapted to the sampling head, and the second hole section is adapted to the main body; And / or, the liquid absorption channel is a capillary channel; And / or, the sealing piece is an aluminum foil.

4. The sample detection device according to claim 2, wherein The base includes a base body and a convex platform arranged on the top surface of the base body, the mixing cavity is formed in the convex platform, and the insertion opening is formed on the side of the convex platform facing away from the base body.

5. The sample detection device according to claim 4, characterized in that, [[ID=I0]]The base further includes an upper cover, the upper cover is covered on the top surface of the base body, and the upper cover is provided with an opening, the opening is aligned with the insertion opening, and the opening is for the sampling head to pass through to pierce the sealing piece and extend into the mixing cavity through the insertion opening.

6. The sample detection device according to claim 5, wherein, At least part of the inner surface of the upper cover is sleeved on the outer circumferential surface of the base body, a clamping convex portion is provided on either the outer circumferential surface of the base body or the inner surface of the upper cover, and a clamping concave portion is provided on the other of the outer circumferential surface of the base body and the inner surface of the upper cover, and the upper cover is clamped with the base body through the cooperation of the clamping convex portion and the clamping concave portion; Or, the upper cover and the base body are integrally provided.

7. The sample detection device according to claim 2, wherein The inner surface of one end of the mixing cavity close to the insertion opening is tightly sealed against the outer surface of the main body of the sampling member.

8. The sample detection device according to any one of claims 1 to 7, characterized in that, The detection tube includes a tube body and a test strip support, the accommodation cavity is formed in the tube body, a viewing window for observing the test strip is provided on the tube wall of the tube body, the test strip support includes an end cover and a support connected to the end cover, the end cover is hermetically covered on the top of the tube body, the sampling member is connected to the bottom of the tube body, and a card slot for placing the test strip is formed on the support.

9. The sample detection device according to claim 8, wherein, A sealing protrusion is formed on one side of the end cap close to the tube body, and the sealing protrusion is embedded in the accommodation cavity at the top end of the tube body and is in sealed contact with the inner surface of the accommodation cavity; and / or, the card slot is adapted to the test strip.

10. The sample detection device according to any one of claims 1 to 7, characterized in that, The main body of the sampling member is detachably sleeved on the outer peripheral surface of the bottom of the test tube; and / or, the number of the liquid inlet holes is set to be multiple, and the multiple liquid inlet holes are distributed at intervals along the circumferential direction of the main body of the sampling member; and / or, the test strip includes an absorption pad with a water absorption function, a nitrocellulose membrane coated with a test line and a quality control line, a conjugate pad coated with a labeled protein conjugate, and a sample pad for absorbing the liquid to be detected, which are sequentially connected along the extending direction of its own length, and one end of the test strip provided with the sample pad is close to the liquid inlet hole.

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