Kit positioning device
By using a combined design of base and preloading parts in the kit positioning device, the positioning problem of the special-shaped bottom kit during the nucleic acid extraction process is solved, and the fast and stable positioning of the kit is achieved, ensuring the stability of detection and simplicity of operation.
Patent Information
- Application Number
- CN202422250049.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-13
- Publication Date
- 2025-08-05
- Estimated Expiration
- 2034-09-13
AI Technical Summary
In the prior art, the special-shaped bottom kit is difficult to accurately locate and fix during the nucleic acid extraction process, resulting in the kit being dumped or offset, affecting the detection stability.
A kit positioning device is designed, including a base and a preloader, with a positioning member and a placement area on the base, the positioning member has an inward recessed positioning surface for contacting the reagent tube, and the preloader is used to fix the reagent kit. The kit is stably positioned on the base through the joint action of the positioning surface and the preloader.
It realizes the fast and stable positioning of the kit, ensuring that the kit is not easily taken out during the nucleic acid extraction process, has a simple structure and is convenient to use, and is suitable for large-volume nucleic acid extraction.
Smart Images

Figure CN223189174U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the field of medical equipment, in particular to a reagent box positioning device. Background Art
[0002] Nucleic acid extraction applications require large sample volumes, such as prenatal screening and early cancer screening. These often require sample volumes exceeding 2ml. When combined with lysis buffer and other reagents, the total volume often reaches over 5ml. Therefore, consumables designed to support large-volume nucleic acid extraction are essential. During nucleic acid extraction and other procedures, the reagent cartridge must be positioned to prevent tipping or shifting during testing, ensuring stable testing and diagnostics.
[0003] Therefore, how to provide a reagent kit positioning device with a simple structure, easy operation and stable positioning is a technical problem that urgently needs to be solved in this field. Utility Model Content
[0004] The main technical problem solved by the utility model is to provide a reagent box positioning device which has a simple structure and can quickly position the reagent box.
[0005] According to a first aspect, the utility model provides a reagent kit positioning device, wherein the reagent kit has a plurality of reagent tubes, and the reagent kit positioning device comprises:
[0006] The base has a positioning member and a placement area for placing the reagent kit; the positioning member is located in the placement area, and the end of the positioning member facing away from the base has a concave positioning surface, the positioning surface is used to contact the reagent tube and pre-position the multiple reagent tubes;
[0007] and at least two pre-tightening members, which are arranged on the base and used for fixing the reagent box on the base.
[0008] In an optional embodiment, the positioning member has a plurality of positioning surfaces, and the plurality of positioning surfaces are in one-to-one contact with a corresponding number of reagent tubes.
[0009] In an optional embodiment, the positioning surface is a spherical arc surface that matches the outer surface of the reagent tube;
[0010] Alternatively, the positioning surface is an arc-shaped surface that matches the outer surface size of the reagent tube, and the generatrixes of at least two of the positioning surfaces are perpendicular to each other.
[0011] In an optional embodiment, the positioning member includes a first positioning member and a second positioning member; the reagent kit positioning device further includes a heating component, and the heating component is heat-transferably connected to the first positioning member.
[0012] In an optional embodiment, the first positioning member has a plurality of positioning surfaces arranged along a first direction, the second positioning member has a plurality of positioning surfaces arranged along a second direction, and the first direction and the second direction are perpendicular.
[0013] In an optional embodiment, the reagent box positioning device further includes a heat insulation board provided on the base, the heat insulation board is located at the bottom of the placement area and is used for heat insulation between the base and the reagent box, and at least the first positioning member is provided on the heat insulation board.
[0014] In an optional embodiment, the reagent box positioning device also includes a stopper, which is provided on the base and arranged around the circumference of the placement area to form a placement space with a certain depth at a position corresponding to the placement area; at least two pre-tightening members are installed on the base and / or the stopper.
[0015] In an optional embodiment, the pre-tightening member has a preset height a from the bottom surface of the placement area, and the preset height a is adapted to the step height of the reagent box to confine the step of the reagent box between the bottom surface of the placement area and the pre-tightening member.
[0016] In an optional embodiment, the pre-tightening member is a ball screw, which can elastically contract along the first direction; the number of the ball screws is four, and the four ball screws are arranged opposite each other in pairs along the first direction.
[0017] In an optional embodiment, the base is further provided with a protruding anti-fool column, which is located in the placement area.
[0018] According to the reagent box positioning device of the above embodiment, the positioning member has a positioning surface that is recessed in the direction close to the placement area. When in use, the reagent box is placed in the placement area of the base, and the tubular outer surface of at least part of the reagent tubes of the reagent box contacts the positioning surface. The positioning surface limits the movement of the reagent box in all directions, and then the positions of the multiple reagent tubes of the reagent box are positioned by the positioning surface. At the same time, the pre-tightening member acts on the reagent box to limit the position of the reagent box and fix the reagent box in the placement area of the base. Under the joint action of the positioning member and the pre-tightening member, the reagent box is stably positioned on the base, ensuring that the reagent box will not be easily taken out during the nucleic acid extraction process. The reagent box positioning device has a simple structure, is easy to use, and can stably position and fix the reagent box. BRIEF DESCRIPTION OF THE DRAWINGS
[0019] Figure 1 This is a schematic diagram of the overall structure of the reagent kit positioning device provided in some embodiments of the present invention.
[0020] Figure 2 for Figure 1 Schematic diagram of another perspective of the reagent kit positioning device.
[0021] Figure 3for Figure 1 Schematic diagram of the reagent kit positioning device as a whole and the reagent kit when in use.
[0022] Figure 4 for Figure 3 Explosion diagram.
[0023] Figure 5 for Figure 4 Schematic diagram from another perspective.
[0024] Figure 6 A schematic structural diagram of a heat shield plate of a reagent box positioning device provided in some embodiments.
[0025] Figure 7 for Figure 6 Another perspective diagram of the heat shield in the .
[0026] Figure 8 Schematic diagram of the assembly of the first positioning member and the heating component in the reagent kit positioning device provided in some embodiments.
[0027] Figure 9 Schematic diagram of the assembly of the heat insulation plate, positioning member and heating component of the reagent kit positioning device provided in some embodiments.
[0028] Figure 10 for Figure 9 Schematic diagram from another perspective.
[0029] Figure 11 This is a schematic diagram of two pre-tightening members with a preset height a on one side cooperating with the steps of the reagent container (the two pre-tightening members on the opposite side are not shown).
[0030] Figure 12 for Figure 11 Front view of .
[0031] Reference numerals: 100 - reagent kit positioning device; 10 - base; 11 - positioning member; 111 - positioning surface; 112 - first positioning member; 113 - second positioning member; 114 - first portion; 115 - second portion; 116 - body; 117 - limiting edge; 12 - through hole; 20 - pre-tightening member; 30 - heating assembly; 31 - temperature control switch; 32 - heating plate; 33 - thermistor; 40 - thermal insulation board; 41 - mounting hole; 50 - stopper; 51 - sub-stopper; 60 - anti-fouling column;
[0032] 1- reagent box; 2- reagent tube; 3- main body; 4- square cover structure; 5- step. DETAILED DESCRIPTION
[0033] The present invention is further described in detail below by means of specific embodiments in conjunction with the accompanying drawings. Similar elements in different embodiments are numbered with associated similar elements. In the following embodiments, many detailed descriptions are provided to enable the present application to be better understood. However, those skilled in the art will readily appreciate that some of the features may be omitted under different circumstances, or may be replaced by other elements, materials, or methods. In some cases, some operations related to the present application are not shown or described in the specification. This is to avoid the core portion of the present application being overwhelmed by excessive descriptions. For those skilled in the art, it is not necessary to describe these related operations in detail. They can fully understand the related operations based on the description in the specification and the general technical knowledge in the art.
[0034] In addition, the features, operations, or characteristics described in the specification may be combined in any appropriate manner to form various embodiments. Furthermore, the steps or actions in the method description may be reordered or adjusted in a manner readily apparent to those skilled in the art. Therefore, the various sequences in the specification and drawings are provided solely for the purpose of clearly describing a particular embodiment and are not intended to be mandatory, unless otherwise specified.
[0035] The serial numbers assigned to components herein, such as "first," "second," etc., are used solely to distinguish the objects being described and do not convey any sequential or technical meaning. References to "connection" and "coupling" herein, unless otherwise specified, include both direct and indirect connections (couplings).
[0036] In the modern medical industry, various inspection projects are often required. After a series of processing work such as sample lysis, mixing, transfer, and nucleic acid extraction, the test is finally carried out. In the nucleic acid extraction step, a test kit is required. There are many types of test kits in the related art. Among them, the bottom of one type of test kit is not a flat structure. The test kit has multiple reagent tubes, and multiple tubular structures are formed at the bottom of the test kit. When using a test kit with such an irregular bottom, it is difficult to accurately position and fix the test kit. Therefore, there is an urgent need to provide a test kit positioning device suitable for this type of test kit.
[0037] The utility model provides a reagent box positioning device, which is suitable for positioning a reagent box with multiple reagent tubes and can easily and quickly position the reagent box. Figure 1-Figure 3The reagent kit positioning device 100 includes a base 10 and at least two pre-tightening members 20 arranged on the base 10, wherein: the base 10 has a positioning member 11 and a placement area for placing the reagent kit 1; the positioning member 11 is located in the placement area, and the end of the positioning member 11 facing away from the base 10 has a concave positioning surface 111, and the positioning surface 111 is used to contact the reagent tube 2 and pre-position multiple reagent tubes 2; the two pre-tightening members 20 are used to fix the reagent kit 1 to the base 10.
[0038] According to the reagent kit positioning device 100 of the above embodiment, the positioning member 11 has a positioning surface 111 that is recessed in the direction close to the placement area. When in use, the reagent kit 1 is placed in the placement area of the base 10, and the tubular outer surface of at least part of the reagent tubes 2 of the reagent kit 1 contacts the positioning surface 111. The positioning surface 111 limits the movement of the reagent kit 1 in all directions, and then the positions of the multiple reagent tubes 2 of the reagent kit 1 are positioned through the positioning surface 111. At the same time, the pre-tightening member 20 acts on the reagent kit 1, which has the effect of limiting the position of the reagent kit 1 and fixing the reagent kit 1 in the placement area of the base 10. Under the joint action of the positioning member 11 and the pre-tightening member 20, the reagent kit 1 is stably positioned on the base 10, ensuring that the reagent kit 1 will not be easily taken out during the nucleic acid extraction process. The reagent kit positioning device 100 has a simple structure, is easy to use, and can stably position and fix the reagent kit 1.
[0039] The above description states that "the positioning surface 111 is used to contact the reagent tubes 2 and pre-position multiple reagent tubes 2", which means that the positioning surface 111 achieves the positioning of the reagent tube 1 by contacting the tubular bottom of the reagent tube 1. The positioning surface 111 can be in positioning contact with one reagent tube 2, or with two or more reagent tubes 2, as long as the final positioning surface 111 can limit the displacement of the reagent tube 1 in the X and Y directions and position the reagent tube 1. For the X and Y directions, please refer to Figure 1 and Figure 2 .
[0040] It should be noted that, in some embodiments, the positioning surface 111 may be a real positioning surface 111 formed at the end of the positioning member 11. In other embodiments, the positioning surface 111 may also be a virtual positioning surface 111 defined by some structures. For example, in some embodiments, a virtual positioning surface 111 may be defined by multiple protrusion structures provided at the end of the positioning member 11. Each protrusion contacts different parts of the multiple reagent tubes 2 of the reagent kit 1, thereby positioning and fixing the reagent kit 1 at multiple points.
[0041] In some embodiments, the positioning member 11 has a plurality of positioning surfaces 111, and the plurality of positioning surfaces 111 are in one-to-one contact with a corresponding number of reagent tubes 2, that is, the number of positioning surfaces 111 does not exceed the number of reagent tubes 2, and one positioning surface 111 corresponds to the position of one reagent tube 2. By simultaneously positioning multiple reagent tubes 2, the positioning accuracy of the positioning member 11 on the reagent kit 1 can be effectively improved.
[0042] Since the bottom of a single reagent tube 2 is hemispherical, the positioning surface 111 can be designed as any solution that can position a spherical surface that matches the bottom of the hemispherical reagent tube 2. For example, in some embodiments, the positioning surface 111 can be a spherical arc surface that matches the outer surface of the reagent tube 2, and the depth of the concave spherical arc surface of the positioning surface 111 can be less than or equal to the depth of the hemispherical bottom of the reagent tube 2, as long as a good positioning contact effect can be achieved. Alternatively, in some embodiments, the positioning surface 111 can also be an arc surface that matches the outer surface size of the reagent tube 2, and the generatrices of at least two of the positioning surfaces 111 are perpendicular to each other. If the generatrices of at least two of the positioning surfaces 111 are perpendicular to each other, the positions of multiple reagent tubes 2 in the plane formed by the X-direction and the Y-direction can be determined, and the multiple arc surfaces correspond to different reagent tubes 2, thereby positioning the reagent kit 1 at multiple points.
[0043] In the nucleic acid extraction step, the reagent kit 1 needs to be heated. In some embodiments, a heating function can be integrated into the reagent kit positioning device 100. For example, please refer to Figure 1 and Figure 9 In some embodiments, the positioning member 11 includes a first positioning member 112 and a second positioning member 113; the reagent cartridge positioning device 100 further includes a heating assembly 30, which is thermally connected to the first positioning member 112. In other words, there are two or more positioning members 11, and the heating assembly 30 is thermally connected to at least one of the positioning members 11. Both the first positioning member 112 and the second positioning member 113 have positioning surfaces 111, which contact the reagent tube 2. The positioning members 11 not only position the reagent cartridge 1 but also transfer heat generated by the heating assembly 30 to the reagent cartridge 1.
[0044] The number of the first positioning member 112 and the second positioning member 113 can be at least one respectively, and the specific number can be selected according to actual needs. In order to reduce the force of the positioning member 11 on the reagent tube 2 on the basis of positioning, and thereby reduce the damage to the structure of the reagent kit 1 to ensure that the reagent kit 1 is intact, in some embodiments, the first positioning member 112 and the second positioning member 113 can be arranged at intervals to contact different positions of the reagent kit 1, improve the positioning accuracy, and make the stress on the reagent kit 1 more dispersed. When there are multiple first positioning members 112, multiple first positioning members 112 can also be arranged at intervals to achieve uniform heating at the same time.
[0045] In some embodiments, in order to position the reagent box 1 more stably and accurately, the first positioning member 112 has a plurality of positioning surfaces 111 arranged along a first direction, and the second positioning member 113 has a plurality of positioning surfaces 111 arranged along a second direction, and the first direction and the second direction are perpendicular. For example, please refer to Figure 1 and Figure 8 The positioning surface 111 is designed as a spherical arc surface, and the first direction is the X direction and the second direction is the Y direction.
[0046] In some embodiments, in order to transfer the heat generated by the heating component 30 to the reagent reagent 1 in a more concentrated manner, the reagent reagent positioning device 100 also includes a heat insulation plate 40 provided on the base 10. The heat insulation plate 40 is located at the bottom of the placement area and is used for heat insulation between the base 10 and the reagent reagent 1. At least the first positioning member 112 is provided on the heat insulation plate 40, so that most of the heat generated by the heating component 30 can be indirectly transferred to the reagent reagent 1 through the first positioning member 112, thereby reducing heat loss to the base 10 and the outside.
[0047] In some embodiments, to facilitate installation of the positioning member 11 and the heating assembly 30, please refer to Figure 4 、 Figure 6 and Figure 7 The base 10 has a through hole 12 that passes through the reagent box 1 in the direction of taking and placing. The heat insulation board 40 is embedded in the through hole 12 and is detachably connected to the base 10. The heat insulation board 40 has a through mounting hole 41 for mounting the positioning member 11. Figure 9 and Figure 10 The positioning member 11 is fixed on the base 10 and / or the heat insulation board 40 , and one end of the positioning member 11 having the positioning surface 111 passes through the mounting hole 41 and extends out to arrange the circuit of the heating component 30 through the mounting hole 41 .
[0048] The present invention does not specifically limit the specific heat transfer connection method between the first positioning member 112 and the heating component 30, and any feasible implementation scheme can be used. For example, in some embodiments, please refer to Figure 8 The first positioning member 112 may include a stacked first part 114 and a second part 115, and the positioning surface 111 is provided at one end of the first part 114 away from the second part 115; the heating assembly 30 includes an electrically connected temperature-controlled switch 31, a heating plate 32 and a thermistor 33, the heating plate 32 is clamped between the first part 114 and the second part 115, and the temperature-controlled switch 31 and the thermistor 33 are partially embedded in the second part 115.
[0049] In some embodiments, the second portion 115 and the heating assembly 30 can be arranged on the side of the heat insulation board 40 away from the positioning surface 111 to further reduce the wiring difficulty and reduce the influence of the heating assembly 30 on the positioning of the reagent box 1. For example, in some embodiments, please refer to Figure 8 The first part 114 includes a connected main body 116 and a limiting edge 117. The limiting edge 117 is arranged on the outer peripheral surface of the end of the main body 116 close to the second part 115 to form a step 5 limiting structure. The positioning surface 111 is located at one end of the main body 116 away from the limiting edge 117. The main body 116 passes through the mounting hole 41 and is positioned by the step 5 limiting structure.
[0050] In some embodiments, the reagent cartridge positioning device 100 further includes a stopper 50, which is disposed on the base 10 and surrounds the placement area circumferentially to form a placement space of a certain depth at a location corresponding to the placement area. The stopper 50 allows a user to intuitively determine the placement area of the base 10, facilitating quick alignment of the positioning member 11 with the reagent tube 2 of the reagent cartridge 1. At least two pre-tightening members 20 may be mounted on the base 10 and / or the stopper 50, as long as they can secure the reagent cartridge 1.
[0051] In some embodiments, the stopper 50 includes two U-shaped sub-stoppers 51 , and the two U-shaped sub-stoppers 51 are detachably disposed on the bottom plate.
[0052] In some embodiments, the pre-tightening member 20 is disposed on the stopper 50 and extends into the placement space to contact the portion of the reagent box 1 placed in the placement space, so as to more stably cooperate with the positioning surface 111 for precise fixation.
[0053] In some embodiments, the pre-tightening member 20 has a preset height a from the bottom surface of the placement area. Figure 11 and Figure 12 The preset height a is adapted to the height of the step 5 of the reagent kit 1 so as to confine the step 5 of the reagent kit 1 between the bottom surface of the placement area and the pre-tightening member 20, thereby not only fixing the reagent kit 1 in the plane where the X and Y directions are located, but also fixing the reagent kit 1 in the Z direction, so that the reagent kit 1 will not fall off the base 10 when there is no sufficiently large external force acting on it.
[0054] The present invention does not impose any specific restrictions on the selection of the pre-tightening member 20. In some embodiments, the pre-tightening member 20 can be a manually adjustable structure, such as a screw for abutting the circumferential side of the reagent kit 1. By manually turning the screw so that the screw abuts the reagent kit 1, or so that the screw does not contact the reagent kit 1, the reagent kit 1 can be taken out and placed and fixed. For example, in some other embodiments, the pre-tightening member 20 can be an elastic and retractable member. During the placement of the reagent kit 1, the abutment against the pre-tightening member 20 compresses the pre-tightening member 20, and the elastic force limits the position of the reagent kit 1, effectively preventing the reagent kit 1 from changing position. In addition, the pre-tightening member 20 can adapt to different reagent kits 1 within a certain size range through adaptive expansion and contraction, thereby improving the applicability of the reagent kit positioning device 100.
[0055] The "circumferential side surface of the reagent box 1" in the above description refers to the outer surface of the reagent box 1. For example, please refer to Figure 3 and Figure 4 In addition to the main body 3 in which a plurality of reagent tubes 2 are distributed, the reagent kit 1 also includes a square cover structure 4 surrounding and connected to the outer periphery of the main body 3. The bottoms of the plurality of reagent tubes 2 of the reagent kit 1 are all located within the square cover structure 4. At this time, the outer surface of the square cover structure 4 and the outer surface of the main body 3 together constitute the circumferential side surface of the reagent kit 1 (i.e., the outer surface of the reagent kit 1). In some embodiments, the pre-tightening member 20 can act on the surface of the square cover structure 4. In other embodiments, the pre-tightening member 20 can also extend between the bottom of the reagent tube 2 and the square cover and abut against the outer surfaces of the plurality of reagent tubes 2. In yet other embodiments, the pre-tightening member 20 can also extend between the plurality of reagent tubes 2 and abut against the outer surfaces of the reagent tubes 2. In other words, the contact and positioning position of the pre-tightening member 20 and the reagent kit 1 can be adaptively improved according to actual needs, as long as the positioning of the reagent kit 1 can be achieved by at least two pre-tightening members 20 abutting against the reagent kit 1 in the first direction relative to each other.
[0056] In some embodiments, please refer to Figure 1 and Figure 4 The pre-tightening member 20 is a ball screw, which can elastically contract along the first direction; the number of the ball screws is four, and the four ball screws are arranged in pairs along the first direction.
[0057] In some embodiments, the base 10 is further provided with a protruding anti-fool column 60, which is located in the placement area. For example, please refer to Figure 1 and Figure 4There is a certain gap between the outer surface of the main body 3 of the reagent box 1 and the square cover structure 4. The depth of one corner of the reagent box 1 is shallower than that of the other three corners. By providing the anti-crash column 60 at the corresponding position of the base 10, if the anti-crash column 60 extends into the shallower corner, it will interfere with the bottom of the corner, making it impossible to place the reagent box 1 on the base 10. If the anti-crash column 60 extends into any of the other three deeper corners, it will not interfere with the reagent box 1, allowing the reagent box 1 to be accurately placed on the base 10 and cooperate with the positioning member 11.
[0058] In summary, the reagent kit positioning device provided by the present invention has at least the following beneficial effects:
[0059] 1. The spherical arc surfaces at the ends of the two first positioning members and one second positioning member are the contoured structures of the bottom of the reagent box, which can position the reagent box more accurately and stably.
[0060] 2. The base and two U-shaped sub-blocks define a placement area of a certain depth, making it easier for the operator to place the reagent kit.
[0061] 3. Four ball screws are embedded in the block, facing each other in pairs along the first direction, which provides a certain limit constraint on the reagent kit. The structure is simple. The positioning of the four ball screws ensures that the reagent kit will not be easily taken out during the nucleic acid extraction process of the extraction mechanism, and also facilitates the removal and placement of the reagent kit.
[0062] 4. The anti-mistake column ensures that the reagent kit is placed in the correct position, ensuring the correctness of the operation.
[0063] The above examples are used to illustrate the present invention, which are only used to help understand the present invention and are not intended to limit the present invention. Those skilled in the art of the present invention can make some simple deductions, modifications or substitutions based on the concept of the present invention.
Claims
1. A reagent box positioning device, the reagent box having multiple reagent tubes, characterized in that: The reagent kit positioning device comprises: A base having a positioning member and a placement area for placing the reagent kit; the positioning member is located in the placement area, and an end of the positioning member facing away from the base has a concave positioning surface, the positioning surface is used to contact the reagent tubes and pre-position the multiple reagent tubes; and at least two pre-tightening members, which are arranged on the base and are used to fix the reagent box on the base.
2. The reagent kit positioning device according to claim 1, wherein The positioning member has a plurality of positioning surfaces, and the plurality of positioning surfaces are in one-to-one contact with a corresponding number of the reagent tubes.
3. The reagent box positioning device according to claim 2, wherein: The positioning surface is a spherical arc surface that matches the outer surface of the reagent tube; Alternatively, the positioning surface is an arc-shaped surface that matches the outer surface size of the reagent tube, and the generatrices of at least two of the positioning surfaces are perpendicular to each other.
4. The reagent kit positioning device according to claim 1, wherein The positioning member includes a first positioning member and a second positioning member; the reagent kit positioning device also includes a heating component, and the heating component is heat-transferably connected to the first positioning member.
5. The reagent kit positioning device according to claim 4, wherein: The first positioning member has a plurality of positioning surfaces arranged along a first direction, and the second positioning member has a plurality of positioning surfaces arranged along a second direction, and the first direction is perpendicular to the second direction.
6. The reagent kit positioning device according to claim 4, wherein: The reagent box positioning device further comprises a heat insulation board provided on the base, the heat insulation board is located at the bottom of the placement area and is used for heat insulation between the base and the reagent box, and at least the first positioning member is provided on the heat insulation board.
7. The reagent kit positioning device according to any one of claims 1 to 6, characterized in that: The reagent box positioning device also includes a stopper, which is arranged on the base and arranged around the circumference of the placement area to form a placement space with a certain depth at a position corresponding to the placement area; the at least two pre-tightening members are installed on the base and / or the stopper.
8. The reagent kit positioning device according to any one of claims 1 to 6, characterized in that: The pre-tightening member has a preset height a from the bottom surface of the placement area, and the preset height a is adapted to the step height of the reagent box to confine the step of the reagent box between the bottom surface of the placement area and the pre-tightening member.
9. The reagent kit positioning device according to any one of claims 1 to 6, characterized in that: The pre-tightening member is a ball screw, which can elastically contract along a first direction; there are four ball screws, which are arranged opposite each other in pairs along the first direction.
10. The reagent kit positioning device according to any one of claims 1 to 6, characterized in that: The base is also provided with a protruding anti-fool column, and the anti-fool column is located in the placement area.