Liquid adding device for blood proteome detection
By designing the liquid-storing device for the liquid storage component and control component, the problem of bottle tilting and frequent solution extraction in the liquid-storing device is solved, the precise addition and efficient operation of the reagent solution are achieved, and the experimental efficiency of blood proteome detection is improved.
Patent Information
- Application Number
- CN202422561699.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-22
- Publication Date
- 2025-08-19
- Estimated Expiration
- 2034-10-22
AI Technical Summary
During the liquid input process of the existing liquid refueling device, the bottle body is easily tilted, resulting in low work efficiency for staff and frequent extraction of the solution in the bottle to increase the operating time.
A liquid adding device including a liquid storage assembly, a liquid adding assembly and a control assembly is designed. The liquid storage assembly is used to store the reagent solution and seal the cover to prevent contamination. The liquid adding assembly realizes precise titration of the reagent through a grip, a burette, a liquid inlet pipe, a water inlet solenoid valve, a micro water pump and a liquid outlet pipe. The control assembly controls the liquid adding volume through a button switch, a micro controller and a flow sensor.
The precise addition of reagent solutions in blood proteome detection is achieved, the solution extraction operation is reduced, the experimental operation efficiency is improved, the external contamination of reagent solutions is prevented, and the overall efficiency of the experiment is improved.
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Figure CN223233852U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the field of liquid adding equipment for blood proteome detection, in particular to a liquid adding device for blood proteome detection. Background Art
[0002] Blood proteomics testing is a method that analyzes proteins in the blood to assess biological status, health status, and disease risk. The research and application of blood proteomics is very important in the fields of medicine and biology. Blood proteomics testing can help discover new biomarkers for early diagnosis, disease monitoring, and efficacy evaluation. Blood proteomics testing requires adding reagent solutions to the separated serum. When adding reagents, it is necessary to use a liquid addition device such as a catheter to improve experimental efficiency and accuracy.
[0003] According to Chinese patent application number: 202220522840.4, a liquid adding device for blood proteome detection is disclosed, including a bottom plate, a vertical plate is symmetrically fixedly connected to the top of the bottom plate, a movable plate is slidably connected to the outer side of the vertical plate, a baffle is symmetrically fixedly connected to the top of the movable plate, a limit plate is fixedly connected to the outer side of the baffle, a plurality of through slots are equidistantly provided inside the limit plate, a plurality of support rods are equidistantly fixedly connected to the top of the bottom plate, the top of the support rod is fixedly connected to the top plate, the bottom of the top plate is symmetrically fixedly connected to the fixed rod, a pressing plate is slidably connected to the outer side of the fixed rod, and a plurality of liquid outlet pipes are equidistantly provided at the bottom of the pressing plate. By squeezing and fixing the container, the container can be prevented from tilting during the liquid input process; multiple bottles of liquid can be input at one time, effectively improving the work efficiency of the staff;
[0004] The existing technology effectively solves the problem that the bottle body is prone to tilting during the liquid input process of the liquid adding device, resulting in low work efficiency of the staff. It has the advantage of being able to prevent the bottle body from tilting, but in actual use, the solution in the bottle needs to be frequently extracted, which increases the operation time.
[0005] In summary, the present invention provides a liquid adding device for blood proteome detection to solve the above problems. Utility Model Content
[0006] In order to solve the above technical problems, the present invention provides the following technical solutions:
[0007] A liquid adding device for blood proteome detection includes a liquid storage component, which includes a liquid storage tank and a sealing cover. The liquid storage component is used to store reagent solution. A liquid adding component is provided on one side of the liquid storage component. The liquid adding component includes a handle, a burette, a liquid inlet pipe, a water inlet solenoid valve, a micro water pump and a liquid outlet pipe. The liquid adding component is used to titrate the reagent. A control component is provided on the surface of the handle. The control component includes a key switch, a micro controller and a flow sensor. The control component is used to control the amount of liquid added.
[0008] Furthermore, in the present invention, the sealing cover is located on the top of the liquid storage tank, and one end of the sealing cover extends to the inner cavity of the liquid storage tank and is movably connected to the inner cavity of the liquid storage tank.
[0009] Furthermore, in the present invention, the burette is installed at the bottom of the handle, the micro water pump is installed at the lower end of the inner cavity of the handle, and the water inlet solenoid valve is installed on the surface of the liquid inlet pipe.
[0010] Furthermore, in the present invention, one end of the liquid inlet tube is connected to the liquid storage tank, the other end of the liquid inlet tube passes through the inner cavity of the handle and is connected to the liquid inlet end of the micro water pump, one end of the liquid outlet tube is connected to the liquid outlet end of the micro water pump, and the other end of the liquid outlet tube is connected to the burette.
[0011] Furthermore, in the present invention, the push button switch is mounted on the surface of the handle, the microcontroller is fixed to the upper end of the inner cavity of the handle, and the flow sensor is mounted on the surface of the burette.
[0012] Furthermore, in the present invention, the output ends of the push button switch and the flow sensor are both connected to a microcontroller, and the output ends of the microcontroller are respectively connected to a water inlet solenoid valve and a micro water pump.
[0013] Beneficial effects: The utility model has the following beneficial effects:
[0014] The utility model has the effect of being able to add reagent solution during blood protein testing by arranging a liquid storage component and a control component. The liquid storage component is used to store the reagent solution to prevent the reagent solution from being contaminated by the outside. The liquid adding component and the control component can cooperate to perform the solution adding operation. The liquid adding component is used to titrate the solution, and the control component is used to control the amount of solution added, thereby reducing the solution extraction operation and effectively improving the operating efficiency of the experiment. BRIEF DESCRIPTION OF THE DRAWINGS
[0015] Figure 1 This is a schematic diagram of the main structure of the utility model;
[0016] Figure 2 This is a schematic structural diagram of the liquid storage component of the utility model in a separated state;
[0017] Figure 3 This is a schematic cross-sectional view of the handle of the utility model;
[0018] Figure 4 This is a schematic diagram of the structure of the micro water pump of the utility model when viewed from above;
[0019] Figure 5 It is a schematic diagram of the system flow of the utility model.
[0020] In the picture:
[0021] 1. Liquid storage component; 101. Liquid storage tank; 102. Sealing cover; 2. Liquid adding component; 201. Handle; 202. Burette; 203. Liquid inlet pipe; 204. Water inlet solenoid valve; 205. Micro water pump; 206. Liquid outlet pipe; 3. Control component; 301. Push button switch; 302. Micro controller; 303. Flow sensor. DETAILED DESCRIPTION
[0022] In order to better understand the technical content of the present invention, specific embodiments are given and described as follows in conjunction with the accompanying drawings. Various aspects of the present invention are described in this disclosure with reference to the accompanying drawings, in which many illustrative embodiments are shown. The embodiments of the present disclosure are not necessarily defined to include all aspects of the present invention. It should be understood that the various concepts and embodiments introduced above, as well as those described in more detail below, can be implemented in any of many ways, because the concepts and embodiments disclosed in the present invention are not limited to any implementation method. In addition, some aspects disclosed in the present invention can be used alone or in any appropriate combination with other aspects disclosed in the present invention.
[0023] Example 1
[0024] like Figure 1-5 As shown, the first embodiment of the utility model provides a liquid adding device for blood proteome detection, including a liquid storage component 1, the liquid storage component 1 includes a liquid storage tank 101 and a sealing cover 102, the liquid storage component 1 is used to store reagent solution, a liquid adding component 2 is provided on one side of the liquid storage component 1, the liquid adding component 2 includes a handle 201, a burette 202, a liquid inlet pipe 203, a water inlet solenoid valve 204, a micro water pump 205 and a liquid outlet pipe 206, the liquid adding component 2 is used to titrate the reagent, and a control component 3 is provided on the surface of the handle 201, the control component 3 includes a key switch 301, a micro controller 302 and a flow sensor 303, and the control component 3 is used to control the amount of liquid added.
[0025] like Figure 1-5As shown, the liquid storage tank 101 and the sealing cover 102 can provide storage space for the reagent solution. The sealing cover 102 is used to seal the inner cavity of the liquid storage tank 101 to prevent external dust from entering the inner cavity of the liquid storage tank 101 and contaminating the reagent solution. The centrifugal force generated by the micro water pump 205 drives the solution in the inner cavity of the liquid storage tank 101 to be diverted to the inner cavity of the burette 202 through the liquid inlet pipe 203 and the liquid outlet pipe 206, and liquid is added through the liquid outlet pipe 206. The micro controller 302 and the flow sensor 303 can cooperate to control the dosage of the reagent solution, thereby facilitating the staff to perform experimental operations. The liquid inlet pipe 203 adopts a hose or a telescopic hose, which can be used conveniently and flexibly. The micro water pump 205 model can be 370SE.
[0026] Example 2
[0027] Reference Figure 1-4 , which is the second embodiment of the present utility model, and this embodiment is based on the previous embodiment.
[0028] In this embodiment, the sealing cover 102 is located on the top of the liquid storage tank 101 , and one end of the sealing cover 102 extends to the inner cavity of the liquid storage tank 101 and is movably connected to the inner cavity of the liquid storage tank 101 .
[0029] The burette 202 is installed at the bottom of the handle 201 , the micro water pump 205 is installed at the lower end of the inner cavity of the handle 201 , and the water inlet solenoid valve 204 is installed on the surface of the liquid inlet pipe 203 .
[0030] One end of the liquid inlet tube 203 is connected to the liquid storage tank 101, the other end of the liquid inlet tube 203 passes through the inner cavity of the handle 201 and is connected to the liquid inlet end of the micro water pump 205, one end of the liquid outlet tube 206 is connected to the liquid outlet end of the micro water pump 205, and the other end of the liquid outlet tube 206 is connected to the burette 202.
[0031] like Figure 1-4 As shown, the water inlet solenoid valve 204 is opened, and then the micro water pump 205 is started. The centrifugal force generated by the high-speed rotation of the micro water pump 205 drives the reagent solution in the inner cavity of the liquid storage tank 101 to flow to the inner cavity of the burette 202 through the diversion of the liquid inlet pipe 203 and the liquid outlet pipe 206, and the liquid adding operation is performed through the burette 202. The handle 201 can be convenient for the staff to hold while also providing installation and protection space for the micro water pump 205. The surface of the liquid storage tank 101 is also provided with scale lines, so that the use of the reagent can be easily observed. The surface of the liquid outlet pipe 206 is provided with a water outlet solenoid valve, and the liquid adding operation of the solution can be closed in time through the water outlet solenoid valve.
[0032] Example 3
[0033] Reference Figure 1 、 3and 5, which are the third embodiment of the present utility model, and this embodiment is based on the first two embodiments.
[0034] In this embodiment, the push button switch 301 is mounted on the surface of the handle 201 , the microcontroller 302 is fixed to the upper end of the inner cavity of the handle 201 , and the flow sensor 303 is mounted on the surface of the burette 202 .
[0035] The output ends of the push button switch 301 and the flow sensor 303 are both connected to the microcontroller 302 , and the output ends of the microcontroller 302 are respectively connected to the water inlet solenoid valve 204 and the micro water pump 205 .
[0036] like Figure 1 、 3 As shown in Figure 5, the push button switch 301 is used to control the start and stop of the micro water pump 205. The micro controller 302, the flow sensor 303 and the micro water pump 205 can all be powered by rechargeable batteries. The flow sensor 303 is used to monitor the liquid flow rate. When the set flow rate value is reached, the flow sensor 303 sends a signal to the micro controller 302, and the micro controller 302 turns off the micro water pump 205 and the water inlet solenoid valve 204, thereby stopping the liquid addition. Pressing the push button switch 301 will send a signal to the micro controller 302, and the liquid addition operation can be performed through 305 and the water inlet solenoid valve 204. The micro controller 302 model can be an ESP32 series single chip microcomputer.
[0037] During use, the dosage is first set through the microcontroller 302, and then the button switch 301 is pressed. The button switch 301 sends a signal to the microcontroller 302, and the microcontroller 302 starts the water inlet solenoid valve 204, the micro water pump 205, and the water outlet solenoid valve on the surface of the liquid outlet pipe 206. The centrifugal force generated by the high-speed rotation of the micro water pump 205 drives the reagent solution in the inner cavity of the liquid storage tank 101 to flow to the inner cavity of the burette 202 through the diversion of the liquid inlet pipe 203 and the liquid outlet pipe 206, and the liquid addition operation is performed through the burette 202. The flow sensor 303 monitors the liquid outlet flow. When the set flow value is reached, the flow sensor 303 sends a signal to the microcontroller 302, and the microcontroller 302 turns off the micro water pump 205 and the water inlet solenoid valve 204, thereby stopping the liquid addition.
[0038] The standard parts used in this application document can all be purchased from the market, and can be customized according to the description in the specification and drawings. The specific connection methods of each part adopt conventional means such as mature bolts, rivets, welding, etc. in the existing technology. The machinery, parts and equipment all adopt conventional models in the existing technology. The control method is automatic control through a controller. The control circuit of the controller can be implemented by simple programming by technicians in this field, which is common knowledge in this field. In addition, this application is mainly used to protect mechanical devices, so this application no longer explains the control method and circuit connection in detail.
[0039] While the present invention has been described above with reference to preferred embodiments, this is not intended to limit the present invention. Persons skilled in the art will readily appreciate that various modifications and variations may be made without departing from the spirit and scope of the present invention. Therefore, the scope of protection of the present invention shall be determined by the claims.
Claims
1. A liquid adding device for blood proteome detection, comprising a liquid storage component (1), characterized in that: The liquid storage component (1) comprises a liquid storage tank (101) and a sealing cover (102). The liquid storage component (1) is used to store a reagent solution. A liquid adding component (2) is provided on one side of the liquid storage component (1). The liquid adding component (2) comprises a handle (201), a burette (202), a liquid inlet pipe (203), a water inlet solenoid valve (204), a micro water pump (205) and a liquid outlet pipe (206). The liquid adding component (2) is used to titrate the reagent. A control component (3) is provided on the surface of the handle (201). The control component (3) comprises a key switch (301), a micro controller (302) and a flow sensor (303). The control component (3) is used to control the amount of liquid added.
2. The liquid adding device for blood proteome detection according to claim 1, characterized in that: The sealing cover (102) is located on the top of the liquid storage tank (101), and one end of the sealing cover (102) extends to the inner cavity of the liquid storage tank (101) and is movably connected to the inner cavity of the liquid storage tank (101).
3. The liquid adding device for blood proteome detection according to claim 1, characterized in that: The burette (202) is installed at the bottom of the handle (201), the micro water pump (205) is installed at the lower end of the inner cavity of the handle (201), and the water inlet solenoid valve (204) is installed on the surface of the liquid inlet pipe (203).
4. The liquid adding device for blood proteome detection according to claim 1, characterized in that: One end of the liquid inlet pipe (203) is in communication with the liquid storage tank (101), the other end of the liquid inlet pipe (203) passes through the inner cavity of the handle (201) and is in communication with the liquid inlet end of the micro water pump (205), one end of the liquid outlet pipe (206) is in communication with the liquid outlet end of the micro water pump (205), and the other end of the liquid outlet pipe (206) is in communication with the burette (202).
5. The liquid adding device for blood proteome detection according to claim 1, characterized in that: The key switch (301) is mounted on the surface of the handle (201), the microcontroller (302) is fixed to the upper end of the inner cavity of the handle (201), and the flow sensor (303) is mounted on the surface of the burette (202).
6. The liquid adding device for blood proteome detection according to claim 1, characterized in that: The output ends of the key switch (301) and the flow sensor (303) are both connected to the microcontroller (302), and the output ends of the microcontroller (302) are respectively connected to the water inlet solenoid valve (204) and the micro water pump (205).
Citation Information
Patent Citations
Liquid adding device for blood proteome detection
CN217249017U