Wet mixing granulator for medicine production

Abstract

The utility model discloses a wet-process mixing granulator for medicine production, relates to the technical field of medicine production, and solves the problems that powder is easy to locally accumulate after entering a production inner cavity of the granulator due to the lack of an effective automatic material distributing mechanism in the conventional wet-process mixing granulator, and further, the powder is not uniformly distributed. The non-uniformity directly affects the quality of the final product of the granulator. Comprising a reaction kettle and a stirring structure arranged on the reaction kettle, and the stirring structure comprises a stirring rod arranged in the reaction kettle; the stirring rod is sleeved with the scraping rod frame, the scraping rod frame is provided with scraping pieces making contact with the inner wall of the reaction kettle, a rod body of the stirring rod is sleeved with an inverted-umbrella-shaped dispersing cover, and a plurality of discharging grooves are formed in the dispersing cover; according to the utility model, the accumulation of powder can be effectively avoided, the uniformity of the powder is improved, and the scraping blade is synchronously driven to scrape the inner wall of the reaction kettle, so that the material can be prevented from being adhered to the inner wall of the reaction kettle.

Description

Technical Field

[0001] The utility model belongs to the technical field of medicine production, in particular to a wet mixing granulator for medicine production. Background Art

[0002] A wet mixing granulator mixes powdered materials with a liquid binder. Its operating principle primarily involves three steps: granulation formation, particle growth, and particle solidification. First, a wetting agent is added to the materials to create a fluid mixture. Then, a mixer and motion mechanism work to form granules. Finally, a particle solidification unit dries and solidifies the wet granules, forming the finished granules. During the granulation process, the material is wetted by a solution sprayed from nozzles within a rotating drum, forming a thin film. The stirring action then causes the material to tumble and mix, ultimately forming granules. This granulation process is widely used in various industries, including pharmaceuticals, food, chemicals, agriculture and feed, and cosmetics.

[0003] At present, during the operation of the current wet mixing granulator, when the powder required for pharmaceutical production is fed into the feed port of the granulator, due to the lack of an effective automated material distribution mechanism, these powders are prone to local accumulation after entering the production cavity of the granulator, which in turn causes the problem of uneven powder distribution. This unevenness directly affects the quality of the final product of the granulator.

[0004] Therefore, based on the above problems, we designed a wet mixing granulator for pharmaceutical production. Utility Model Content

[0005] The present invention aims to solve at least one of the technical problems existing in the prior art. To this end, the present invention provides a wet mixing granulator for pharmaceutical production. The wet mixing granulator for pharmaceutical production solves the problem that during the operation of existing wet mixing granulators, when the powder materials required for pharmaceutical production are fed into the feed port of the granulator, the powder materials tend to accumulate locally after entering the production chamber of the granulator due to the lack of an effective automated material distribution mechanism, thereby causing uneven distribution of the powder materials. This unevenness directly affects the quality of the final product of the granulator.

[0006] To achieve the above-mentioned object, according to an embodiment of the first aspect of the present invention, a wet mixing granulator for pharmaceutical production is provided, comprising a reactor and a stirring structure provided on the reactor, wherein the stirring structure comprises a stirring rod provided in the reactor;

[0007] Also includes:

[0008] A scraper frame is sleeved on the stirring rod, and the scraper frame is provided with a scraper that contacts the inner wall of the reactor. The rod body of the stirring rod is sleeved with an inverted umbrella-shaped dispersion cover, and the dispersion cover is provided with several discharge troughs;

[0009] The outer barrel is arranged on the reactor, and a material storage inner barrel is rotatably arranged inside the outer barrel, a material discharge port is arranged on the bottom surface of the material storage inner barrel, an annular groove is arranged on the inner wall of the outer barrel, and the material discharge port of the material storage inner barrel rotates in the annular groove, and a material guide tube is arranged on the outer barrel.

[0010] A further improvement is that the discharge port of the material storage inner cylinder coincides with the top surface opening of the material guide tube when the inner cylinder rotates.

[0011] A further improvement is that a servo motor is provided on the top surface of the outer barrel, and the main shaft of the servo motor is connected to the material storage inner barrel.

[0012] A further improvement is that the inner bottom surface of the material storage inner cylinder is an inclined surface, and the discharge end of the material guide pipe is located above the dispersion cover.

[0013] A further improvement is that the reactor is provided with an exhaust port, a one-way exhaust valve is mounted on the exhaust port via a fixing bolt, and the one-way exhaust valve is communicated with the reaction cavity of the reactor.

[0014] A further improvement is that feeding ports are provided at the same height as the outer barrel and the inner barrel for storing materials, and a rubber plug plate is provided in the feeding port.

[0015] Compared with the prior art, the beneficial effects of the present invention are:

[0016] The utility model starts the servo motor to drive the storage inner cylinder to rotate, so that the discharge port of the storage inner cylinder rotates in the annular groove. Whenever the discharge port of the storage inner cylinder is accurately connected with the guide tube, a constant and appropriate amount of powder is accurately dropped into the guide tube within a unit time. Subsequently, the powder slides onto the dispersion cover along the trajectory of the guide tube, and then the stirring rod of the driving device is rotated. When the stirring rod rotates, the dispersion cover is synchronously driven to rotate, so that the powder in the dispersion cover is sprinkled into the interior of the reactor through several discharge troughs. This process can effectively avoid the accumulation of powder, improve the uniformity of powder, and improve the production quality. When the stirring rod rotates, the scraper frame and the scraper blade can be synchronously driven to rotate, so that the scraper blade scrapes the inner wall of the reactor, which can prevent the material from sticking to the inner wall of the reactor and avoid inconvenience in later cleaning. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0018] Figure 2 This is a schematic diagram of the cross-sectional structure of the utility model;

[0019] Figure 3 It is a schematic diagram of the cross-section of the outer barrel and the inner barrel for storing materials of the utility model from a top view.

[0020] Markings in the figure:

[0021] 1. Reactor; 11. Stirring structure; 111. Stirring rod; 12. One-way exhaust valve; 2. Outer barrel; 21. Servo motor; 22. Material guide tube; 23. Annular groove; 3. Scraper rod holder; 31. Scraper; 4. Inner barrel for material storage; 41. Discharge port; 42. Rubber plug; 5. Dispersion cover; 51. Discharge chute. DETAILED DESCRIPTION

[0022] The following will clearly and completely describe the technical solutions of the present invention in conjunction with the embodiments. Obviously, the embodiments described are only a part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0023] like Figure 1 As shown, a wet mixing granulator for pharmaceutical production includes a reactor 1 and a stirring structure 11 disposed on the reactor 1, wherein the stirring structure 11 includes a stirring rod 111 disposed in the reactor 1;

[0024] like Figure 2 and Figure 3 As shown, the embodiment includes: an outer barrel 2, which is arranged on the reactor 1, a material storage inner barrel 4 is rotatably arranged in the outer barrel 2, a material discharge port 41 is arranged on the bottom surface of the material storage inner barrel 4, an annular groove 23 is arranged on the inner wall of the outer barrel 2, the material discharge port 41 of the material storage inner barrel 4 rotates in the annular groove 23, and a material guide pipe 22 is arranged on the outer barrel 2;

[0025] Specifically, a servo motor 21 is provided on the top surface of the outer barrel 2, and the main shaft of the servo motor 21 is connected to the storage inner barrel 4. When the storage inner barrel 4 rotates, the discharge port 41 coincides with the top surface of the guide tube 22. The inner bottom surface of the storage inner barrel 4 is an inclined surface, and the design of the inclined surface facilitates discharge.

[0026] like Figure 2The stirring rod 111 of the embodiment of the present invention is a kind of stirring rod 111 of the present invention, which is a kind of stirring rod 111 of the present invention. The stirring rod 111 is provided with a scraper 31 on the stirring rod 111 and is in contact with the inner wall of the reactor 1. The stirring rod 111 is provided with a dispersion cover 5. The dispersion cover 5 is provided with a plurality of discharge troughs 51. The discharge end of the guide tube 22 is located above the dispersion cover 5. The servo motor 21 is started to drive the storage inner cylinder 4 to rotate, so that the discharge port 41 of the storage inner cylinder 4 rotates in the annular groove 23. Whenever the discharge port 41 of the storage inner cylinder 4 is accurately docked with the guide tube 22, an appropriate amount of powder is accurately dropped into the guide tube 22 per unit time. Then, the powder slides into the dispersion cover 5 along the trajectory of the guide tube 22, and then the stirring rod 111 of the driving device is rotated. When the stirring rod 111 rotates, the dispersion cover 5 is synchronously driven to rotate, so that the powder in the dispersion cover 5 is sprinkled into the interior of the reactor 1 through the plurality of discharge troughs 51. This process can effectively avoid the accumulation of powder and improve the uniformity of the powder.

[0027] Specifically, a feeding port is provided at the same height as the outer barrel 2 and the inner barrel 4 for storing materials, and a rubber plug plate 42 is provided in the feeding port for adding powder;

[0028] In this embodiment, an exhaust port is further provided on the reactor 1, and a one-way exhaust valve 12 is installed on the exhaust port by a fixing bolt. The one-way exhaust valve 12 is communicated with the reaction chamber of the reactor 1. The one-way exhaust valve 12 is used to discharge the gas and relieve the pressure when the pressure in the reactor 1 is too high, thereby effectively reducing the pressure in the reaction chamber, thereby avoiding certain accidents caused by excessive pressure.

[0029] like Figures 1 to 3 As shown, in this embodiment, before the application document is implemented, the stirring structure 11 is further configured with a driving device, which drives the stirring rod 111 to rotate; a PLC control system terminal is also configured, and the PLC control system terminal is used to control the servo motor 21 and the driving device; it should also be noted that this application document only aims to improve the shortcomings of the existing wet mixing granulator during operation. When the powder required for pharmaceutical production is fed into the feed port of the granulator, due to the lack of an effective automatic material distribution mechanism, these powders are prone to local accumulation after entering the production cavity of the granulator, thereby causing uneven distribution of the powder. This unevenness directly affects the quality of the final product of the granulator. Other aspects are not involved. The working principle of the wet mixing granulator for pharmaceutical production is introduced as follows:

[0030] During installation and use, the on-site staff opens the rubber stopper 42, places the pharmaceutical production powder into the storage inner cylinder 4, then closes the rubber stopper 42, and starts the servo motor 21 to drive the storage inner cylinder 4 to rotate, so that the discharge port 41 of the storage inner cylinder 4 rotates in the annular groove 23. Whenever the discharge port 41 of the storage inner cylinder 4 is accurately docked with the guide pipe 22, an appropriate amount of powder per unit time is accurately dropped into the guide pipe 22, and then the powder slides along the track of the guide pipe 22 onto the dispersion cover 5;

[0031] Then, the stirring rod 111 of the driving device rotates, and the dispersion cover 5 is synchronously driven to rotate when the stirring rod 111 rotates, so that the powder in the dispersion cover 5 is sprinkled into the interior of the reactor 1 through several discharge troughs 51. This process can effectively avoid the accumulation of powder and improve the uniformity of the powder; when the stirring rod 111 rotates, it can synchronously drive the scraper frame 3 and the scraper 31 to rotate, so that the scraper 31 scrapes the inner wall of the reactor 1, which can prevent the material from sticking to the inner wall of the reactor 1 and avoid inconvenience in later cleaning.

[0032] The above embodiments are only used to illustrate the technical method of the present invention and are not intended to limit the present invention. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical method of the present invention may be modified or replaced by equivalents without departing from the spirit and scope of the technical method of the present invention.

Claims

1. A wet mixing granulator for pharmaceutical production, comprising a reactor (1) and a stirring structure (11) arranged on the reactor (1), wherein the stirring structure (11) comprises a stirring rod (111) arranged in the reactor (1); It is characterized by: Also includes: A scraper frame (3) is sleeved on the stirring rod (111), and a scraper (31) is provided on the scraper frame (3) for contacting the inner wall of the reactor (1). An inverted umbrella-shaped dispersion cover (5) is sleeved on the rod body of the stirring rod (111), and a plurality of discharge troughs (51) are provided on the dispersion cover (5); An outer barrel (2) is arranged on a reaction kettle (1); a material storage inner barrel (4) is rotatably arranged inside the outer barrel (2); a discharge port (41) is arranged on the bottom surface of the material storage inner barrel (4); an annular groove (23) is arranged on the inner wall of the outer barrel (2); the discharge port (41) of the material storage inner barrel (4) rotates in the annular groove (23); and a material guide pipe (22) is arranged on the outer barrel (2).

2. A wet mixing granulator for pharmaceutical production according to claim 1, characterized in that, When the material storage inner cylinder (4) rotates, the material discharge port (41) and the top surface pipe opening of the material guide pipe (22) coincide with each other.

3. A wet mixing granulator for pharmaceutical production according to claim 1, characterized in that, A servo motor (21) is provided on the top surface of the outer barrel (2), and the main shaft of the servo motor (21) is connected to the material storage inner barrel (4).

4. A wet mixing granulator for pharmaceutical production according to claim 1, characterized in that, The inner bottom surface of the material storage inner cylinder (4) is an inclined surface, and the discharge end of the material guide pipe (22) is located above the dispersion cover (5).

5. A wet mixing granulator for pharmaceutical production according to claim 1, characterized in that, The reactor (1) is provided with an exhaust port, on which a one-way exhaust valve (12) is mounted via a fixing bolt, and the one-way exhaust valve (12) is in communication with the reaction cavity of the reactor (1).

6. A wet mixing granulator for pharmaceutical production according to claim 1, characterized in that, Feeding ports are provided at the same height as the outer barrel (2) and the material storage inner barrel (4), and a rubber plug plate (42) is provided in the feeding port.

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