Mixing device for raw material processing based on ethyl 4-chloroacetoacetate

Abstract

The utility model discloses a mixing device based on 4-chloroacetoacetic acid ethyl ester raw material processing, and relates to the technical field of 4-chloroacetoacetic acid ethyl ester raw material processing and mixing, the mixing device comprises a support frame, the top surface of the support frame is provided with a dosing unit, the inner side of the dosing unit is provided with a filtering unit, and the filtering unit is connected with the dosing unit. A stirring unit is arranged on the top surface of the dosing unit, the filtering unit comprises a liquid inlet box, the liquid inlet box is arranged on the inner side of the dosing unit, a mounting frame is slidably connected to the inner side of the liquid inlet box, a first T-shaped rod is arranged in the mounting frame in a penetrating mode, and a first spring is arranged on the outer side of the first T-shaped rod in a sleeving mode. Through the arrangement of the liquid inlet box, the mounting frame, the T-shaped rod I, the spring I, the positioning block and the filter screen, the effect of conveniently filtering impurities in an ethyl 4-chloroacetoacetate raw material before processing and mixing is achieved, so that the quality of a finished product is improved, and meanwhile, the effect of conveniently detaching and cleaning the filter screen after long-time use is achieved.

Description

Technical Field

[0001] The utility model relates to the technical field of ethyl 4-chloroacetoacetate raw material processing and mixing, in particular to a mixing device for processing ethyl 4-chloroacetoacetate raw material. Background Art

[0002] Ethyl 4-chloroacetoacetate is an important pharmaceutical intermediate, used in the production of atorvastatin calcium and oxiracetam, two highly effective cardiovascular and cerebrovascular treatments. Several US pharmaceutical companies already produce this drug. Its downstream product, aminothiocarbamate, is primarily used in the APIs of third- and fourth-generation cephalosporins. Cephalosporins are dozens of times more effective than penicillin and have minimal toxic side effects, offering excellent development and production prospects.

[0003] The main raw materials for preparing ethyl 4-chloroacetoacetate include ethyl chloroacetate and chloroacetyl chloride. Ethyl chloroacetate is a common organic reagent that can be prepared through an alcohol acid-ester transesterification reaction. Chloroacetyl chloride is a toxic, colorless liquid that can be prepared by reacting chlorinated acetic acid with sodium sulfite.

[0004] Currently, during the production and mixing process of ethyl 4-chloroacetoacetate, there is a problem that impurities in the raw materials cannot be filtered out, which leads to impurities in the size of the mixed ethyl 4-chloroacetoacetate, affecting the effect of the use of ethyl 4-chloroacetoacetate. Utility Model Content

[0005] The purpose of the utility model is to provide a mixing device for processing ethyl 4-chloroacetoacetate raw material to solve the problems raised in the above background technology.

[0006] In order to solve the above technical problems, the technical solution adopted by the present invention is:

[0007] A mixing device for processing ethyl 4-chloroacetoacetate raw material comprises a support frame, a dosing unit is arranged on the top surface of the support frame, a filtering unit is arranged on the inner side of the dosing unit, and a stirring unit is arranged on the top surface of the dosing unit.

[0008] The filter unit includes a liquid inlet box, which is arranged on the inner side of the dosing unit, and the inner side of the liquid inlet box is slidably connected to a mounting frame, a T-shaped rod is provided through the interior of the mounting frame, a spring is sleeved on the outer side of the T-shaped rod, one end of the spring is fixedly connected to one side of the T-shaped rod, one side of the spring is fixedly connected to the inside of the mounting frame, one end of the T-shaped rod is slidably connected to a positioning block, one side of the positioning block is fixedly connected to a filter screen, and the inner side of the positioning block is slidably connected to the inside of the mounting frame.

[0009] A further improvement of the technical solution of the present utility model is that the dosing unit includes a mixing tank, which is fixedly connected to the inner side of the top surface of the support frame, the bottom surface of the mixing tank is sleeved with a liquid outlet pipe, the top surface of the mixing tank is fixedly connected to a liquid storage tank, and the inner side of the liquid storage tank is sleeved with a dosing pipe.

[0010] By adopting the above technical solution, the mixed ethyl chloroacetoacetate can be easily discharged through the arrangement of the mixing tank and the liquid outlet pipe.

[0011] A further improvement of the technical solution of the present utility model is that: an infusion tube is sleeved inside the liquid storage tank, a pump is sleeved inside the infusion tube, one end of the infusion tube is rotatably sleeved with a connecting tube, and the inner side of the connecting tube is rotatably connected to the inner bottom surface of the mixing tank.

[0012] By adopting the above technical solution, through the arrangement of the liquid storage tank, the dosing tube, the infusion tube, the pump and the connecting tube, the required added material can be discharged during the mixing process, so that it can be directly mixed more fully with the ethyl 4-chloroacetoacetate raw material.

[0013] A further improvement of the technical solution of the present utility model is that: the stirring unit includes a motor, the motor is fixedly connected to the inner side of the top surface of the mixing tank, the output end of the motor is transmission-connected to a rotating rod, the interior of the rotating rod is set to be hollow, and a plurality of liquid spray holes are set on the inner side of the rotating rod, and one end of the rotating rod is fixedly sleeved with one end of the connecting pipe.

[0014] By adopting the above technical solution, the main stirring rod can be easily disassembled and repaired through the arrangement of the motor, the rotating rod, the spray hole and the fixing groove.

[0015] A further improvement of the technical solution of the present invention is that: the inner side of the rotating rod is threadedly connected with a fixing groove, the inner side of the fixing groove is fixedly connected with several main stirring rods, the inner side of the main stirring rod is rotatably connected with several fixing rods, the inner side of the fixing rod is fixedly connected with several through-hole plates, and a scraper unit is provided on the inner side of the main stirring rod.

[0016] By adopting the above technical solution, the main stirring rod, the fixed rod and the through-hole plate are arranged to achieve the effect of fully mixing the ethyl 4-chloroacetoacetate raw material. At the same time, the through-hole plate is arranged to allow the liquid to flow through the holes and generate vortices, thereby making the mixing more complete.

[0017] A further improvement of the technical solution of the present invention is that the scraper unit includes a connecting plate, which is fixedly connected to the inner side of the main stirring rod, and a T-shaped rod 2 is provided through the inner side of the connecting plate, and a spring 2 is sleeved on the outer side of the T-shaped rod 2.

[0018] By adopting the above technical solution, the scraper is closely attached to the inner wall of the mixing tank through the arrangement of the connecting plate, the second T-shaped rod and the second spring.

[0019] A further improvement of the technical solution of the present utility model is that one end of the second spring is fixedly connected to one side of the second T-shaped rod, one end of the second spring is fixedly connected to one side of the connecting plate, and one end of the second T-shaped rod is fixedly connected to a scraper.

[0020] By adopting the above technical solution and setting the scraper, the material adhering to the inner wall of the mixing tank can be scraped off easily, thereby avoiding the phenomenon of adhesion.

[0021] Due to the adoption of the above technical solution, the present invention has achieved the following technical advancements compared to the prior art:

[0022] 1. The utility model provides a mixing device for processing ethyl 4-chloroacetoacetate raw material. By arranging a liquid inlet box, a mounting frame, a T-shaped rod, a spring, a positioning block and a filter screen, it is achieved that impurities inside the ethyl 4-chloroacetoacetate raw material are filtered out before processing and mixing, thereby improving the quality of the finished product. At the same time, the filter screen can be easily disassembled and cleaned after long-term use. By arranging a liquid storage tank, a dosing tube, an infusion tube, a pump and a connecting tube, it is achieved that the required added materials are discharged during the mixing process, so that they are directly mixed more fully with the ethyl 4-chloroacetoacetate raw material.

[0023] 2. The utility model provides a mixing device for processing ethyl 4-chloroacetoacetate raw materials. By setting a main stirring rod, a fixed rod and a through-hole plate, the ethyl 4-chloroacetoacetate raw material can be fully mixed. At the same time, the through-hole plate allows the liquid to flow through the holes and generate vortexes, making the mixing more complete. The scraper can facilitate the scraping of materials adhering to the inner wall of the mixing tank to avoid adhesion. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 It is a schematic cross-sectional view of the three-dimensional structure of the utility model;

[0025] Figure 2 This is a schematic cross-sectional view of the dosing unit of the present invention;

[0026] Figure 3 This is a schematic structural diagram of the filter unit of the utility model;

[0027] Figure 4 This is a schematic structural diagram of the stirring unit of the utility model;

[0028] Figure 5 For this utility model Figure 4A magnified schematic diagram of the A structure.

[0029] In the figure: 1. Support frame; 2. Dosing unit; 21. Mixing tank; 22. Liquid outlet pipe; 23. Liquid storage tank; 24. Dosing pipe; 25. Infusion pipe; 26. Pump; 27. Connecting pipe; 3. Filter unit; 31. Liquid inlet box; 32. Mounting frame; 33. T-bar 1; 34. Spring 1; 35. Positioning block; 36. Filter screen; 4. Stirring unit; 41. Motor; 42. Rotating rod; 43. Liquid spray hole; 44. Fixing groove; 45. Main stirring rod; 46. Fixing rod; 47. Through-hole plate; 48. Scraper unit; 481. Connecting plate; 482. T-bar 2; 483. Spring 2; 484. Scraper. DETAILED DESCRIPTION

[0030] The present invention is further described in detail below with reference to the embodiments:

[0031] Example 1

[0032] like Figure 1-5 As shown, the utility model provides a mixing device for processing ethyl 4-chloroacetoacetate raw material, comprising a support frame 1, a dosing unit 2 is provided on the top surface of the support frame 1, a filtering unit 3 is provided on the inner side of the dosing unit 2, a stirring unit 4 is provided on the top surface of the dosing unit 2, the filtering unit 3 comprises a liquid inlet box 31, the liquid inlet box 31 is provided on the inner side of the dosing unit 2, a mounting frame 32 is slidably connected to the inner side of the liquid inlet box 31, a T-shaped rod 33 is provided inside the mounting frame 32, a spring 34 is provided on the outer side of the T-shaped rod 33, one end of the spring 34 is fixedly connected to one side of the T-shaped rod 33, and the spring 34 is fixedly connected to the one side of the T-shaped rod 33. One side of 34 is fixedly connected to the inside of the installation frame 32, one end of the T-shaped rod 33 is slidably connected to the positioning block 35, one side of the positioning block 35 is fixedly connected to the filter screen 36, and the inner side of the positioning block 35 is slidably connected to the inside of the installation frame 32. The raw materials for processing ethyl 4-chloroacetoacetate are added through the liquid inlet box 31, and the impurities in the ethyl 4-chloroacetoacetate raw materials are filtered through the filter screen 36 inside the liquid inlet box 31. After long-term use, the installation frame 32 is removed and the T-shaped rod 33 is pulled out from the inner side of the positioning block 35, and the filter screen 36 can be disassembled and replaced.

[0033] Example 2

[0034] like Figure 1-5As shown, on the basis of Example 1, the utility model provides a technical solution: preferably, the stirring unit 4 includes a motor 41, the motor 41 is fixedly connected to the inner side of the top surface of the mixing tank 21, the output end of the motor 41 is transmission-connected to a rotating rod 42, the interior of the rotating rod 42 is set to be hollow, and a plurality of liquid spray holes 43 are set on the inner side of the rotating rod 42, one end of the rotating rod 42 is fixedly sleeved with one end of the connecting pipe 27, the inner side of the rotating rod 42 is threadedly connected to a fixing groove 44, and the inner side of the fixing groove 44 is fixedly connected to a plurality of main stirring rods 4 5. The inner side of the main stirring rod 45 is rotatably connected to a plurality of fixed rods 46. The inner side of the fixed rod 46 is fixedly connected to a plurality of through-hole plates 47. A scraper unit 48 is provided on the inner side of the main stirring rod 45. After filtration, the ethyl 4-chloroacetoacetate raw material enters the interior of the mixing tank 21. Then, the motor 41 is controlled to drive the fixed groove 44 on the inner side of the rotating rod 42 to rotate, thereby driving the main stirring rod 45 to mix the solution inside the mixing tank 21. At the same time, the solution generates a vortex through the inner side of the through-hole plate 47, so that it is fully mixed.

[0035] Example 3

[0036] like Figure 1-5 As shown, on the basis of Example 1, the utility model provides a technical solution: preferably, the dosing unit 2 includes a mixing tank 21, the mixing tank 21 is fixedly connected to the inner side of the top surface of the support frame 1, the bottom surface of the mixing tank 21 is sleeved with a liquid outlet pipe 22, the top surface of the mixing tank 21 is fixedly connected to a liquid storage tank 23, the inner side of the liquid storage tank 23 is sleeved with a dosing pipe 24, the interior of the liquid storage tank 23 is sleeved with an infusion pipe 25, the inner side of the infusion pipe 25 is sleeved with a pump 26, one end of the infusion pipe 25 is rotatably sleeved with a connecting pipe 27, the inner side of the connecting pipe 27 is rotatably connected to the inner bottom surface of the mixing tank 21, the scraper unit 48 includes a connecting plate 481, the connecting plate 481 is fixedly connected to the inner side of the main stirring rod 45, a T-shaped rod 482 is provided on the inner side of the connecting plate 481, a spring 483 is sleeved on the outer side of the T-shaped rod 482, and one end of the spring 483 is fixedly connected to the T-shaped rod On one side of the second rod 482, one end of the second spring 483 is fixedly connected to one side of the connecting plate 481, and one end of the T-shaped rod 482 is fixedly connected to a scraper 484 to fully mix them, and the required solvent is added to the interior of the liquid storage tank 23 through the dosing tube 24, and the dosing unit 2 is controlled to pump out the solvent inside the liquid storage tank 23 through the infusion tube 25, and transport it to the interior of the rotating rod 42 through the connecting tube 27. Then, during the stirring process, the added solvent is pumped out through the spray hole 43, and the solvent is fully mixed. During the mixing process, the scraper 484 is driven to fit closely to the inner wall of the mixing tank 21 through the mutual cooperation between the T-shaped rod 482 and the second spring 483 set on the inner side of the connecting plate 481, so as to avoid the solvent sticking to the inner wall of the mixing tank 21 and affecting the mixing effect. After the mixing is completed, the 4-chloroacetoacetic acid ethyl ester can be discharged through the liquid outlet pipe 22.

[0037] Specifically describe the working principle of this mixing device based on ethyl 4-chloroacetoacetate raw material processing below.

[0038] like Figure 1-5 As shown, the raw material for processing ethyl 4-chloroacetoacetate is added through the liquid inlet box 31, and the impurities in the ethyl 4-chloroacetoacetate raw material are filtered through the filter screen 36 inside the liquid inlet box 31. After long-term use, the installation frame 32 is removed and the T-shaped rod 33 is pulled out from the inner side of the positioning block 35, and the filter screen 36 can be disassembled and replaced. After the filtration is completed, the ethyl 4-chloroacetoacetate raw material enters the interior of the mixing tank 21, and the motor 41 is controlled to drive the fixed groove 44 inside the rotating rod 42 to rotate, thereby driving the main stirring rod 45 to mix the solution inside the mixing tank 21. At the same time, the solution generates a vortex through the inner side of the through-hole plate 47, so that it is fully Mixing, adding the required solvent to the interior of the liquid storage tank 23 through the dosing tube 24, controlling the dosing unit 2 to pump out the solvent inside the liquid storage tank 23 through the infusion tube 25, and transporting it to the interior of the rotating rod 42 through the connecting tube 27, and then during the stirring process, pumping out the added solvent through the spray hole 43, and then fully mixing the solvent. During the mixing process, the T-shaped rod 2 482 and the spring 2 483 provided on the inner side of the connecting plate 481 cooperate with each other to drive the scraper 484 to fit closely to the inner wall of the mixing tank 21, thereby preventing the solvent from sticking to the inner wall of the mixing tank 21 and affecting the mixing effect. After the mixing is completed, the 4-chloroacetoacetic acid ethyl ester can be discharged through the liquid outlet pipe 22.

[0039] The above generally describes the present invention in detail. However, it is obvious to those skilled in the art that modifications or improvements may be made to the present invention. Therefore, modifications or improvements that do not depart from the spirit of the present invention are within the scope of protection of the present invention.

Claims

1. A mixing device for processing ethyl 4-chloroacetoacetate raw material, comprising a support frame (1), characterized in that: A dosing unit (2) is provided on the top surface of the support frame (1), a filtering unit (3) is provided on the inner side of the dosing unit (2), and a stirring unit (4) is provided on the top surface of the dosing unit (2); The filter unit (3) includes a liquid inlet box (31), which is arranged on the inner side of the dosing unit (2). The inner side of the liquid inlet box (31) is slidably connected to a mounting frame (32). A T-shaped rod (33) is provided inside the mounting frame (32). A spring (34) is sleeved on the outer side of the T-shaped rod (33). One end of the spring (34) is fixedly connected to one side of the T-shaped rod (33). One side of the spring (34) is fixedly connected to the inside of the mounting frame (32). One end of the T-shaped rod (33) is slidably connected to a positioning block (35). One side of the positioning block (35) is fixedly connected to a filter screen (36). The inner side of the positioning block (35) is slidably connected to the inside of the mounting frame (32).

2. A mixing device for processing ethyl 4-chloroacetoacetate raw material according to claim 1, characterized in that: The dosing unit (2) comprises a mixing tank (21), the mixing tank (21) is fixedly connected to the inner side of the top surface of the support frame (1), the bottom surface of the mixing tank (21) is sleeved with a liquid outlet pipe (22), the top surface of the mixing tank (21) is fixedly connected to a liquid storage tank (23), and the inner side of the liquid storage tank (23) is sleeved with a dosing pipe (24).

3. A mixing device for processing ethyl 4-chloroacetoacetate raw material according to claim 2, characterized in that: The interior of the liquid storage tank (23) is sleeved with a liquid infusion tube (25), the inner side of the liquid infusion tube (25) is sleeved with a pump (26), one end of the liquid infusion tube (25) is rotatably sleeved with a connecting tube (27), and the inner side of the connecting tube (27) is rotatably connected to the inner bottom surface of the mixing tank (21).

4. A mixing device for processing ethyl 4-chloroacetoacetate raw material according to claim 1, characterized in that: The stirring unit (4) comprises a motor (41), the motor (41) being fixedly connected to the inner side of the top surface of the mixing tank (21), the output end of the motor (41) being transmission-connected to a rotating rod (42), the interior of the rotating rod (42) being arranged to be hollow, a plurality of liquid spraying holes (43) being arranged on the inner side of the rotating rod (42), and one end of the rotating rod (42) being fixedly sleeved to one end of the connecting pipe (27).

5. A mixing device for processing ethyl 4-chloroacetoacetate raw material according to claim 4, characterized in that: The inner side of the rotating rod (42) is threadedly connected to a fixing groove (44), the inner side of the fixing groove (44) is fixedly connected to a plurality of main stirring rods (45), the inner side of the main stirring rod (45) is rotatably connected to a plurality of fixing rods (46), the inner side of the fixing rod (46) is fixedly connected to a plurality of through-hole plates (47), and the inner side of the main stirring rod (45) is provided with a scraper unit (48).

6. A mixing device for processing ethyl 4-chloroacetoacetate raw material according to claim 5, characterized in that: The scraper unit (48) includes a connecting plate (481), which is fixedly connected to the inner side of the main stirring rod (45). A second T-shaped rod (482) is provided on the inner side of the connecting plate (481), and a second spring (483) is sleeved on the outer side of the second T-shaped rod (482).

7. A mixing device for processing ethyl 4-chloroacetoacetate raw material according to claim 6, characterized in that: One end of the second spring (483) is fixedly connected to one side of the second T-shaped rod (482), one end of the second spring (483) is fixedly connected to one side of the connecting plate (481), and one end of the second T-shaped rod (482) is fixedly connected to a scraper (484).

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