Auxiliary device for preparing paclitaxel for injection

By designing a paclitaxel preparation aid for injection, using the gravity shaking of the placement seat and the automatic clamping of the clamping claws, the problems of poor solubility of paclitaxel and time-consuming and labor-intensive preparation are solved, the dissolution efficiency and preparation efficiency are improved, and the burden on the dispensing staff is reduced.

CN223337213UActive Publication Date: 2025-09-16THE FIRST AFFILIATED HOSPITAL OF XIAMEN UNIV
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Patent Information

Application Number
CN202422762251.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-11-13
Publication Date
2025-09-16
Estimated Expiration
2034-11-13

AI Technical Summary

Technical Problem

In the prior art, paclitaxel albumin-bound injectable drugs have poor solubility, are time-consuming and labor-intensive to prepare, and are prone to generating bubbles, thus affecting preparation efficiency.

Method used

A paclitaxel dispensing aid for injection was designed, which includes a base, a placement seat, and a clamping mechanism. The gravity of the placement seat is used to shake the medicine bottle, and the special structure of the clamp and the counterweight block are used to achieve automatic clamping and oscillation of the medicine bottle, avoiding violent vibrations and improving dissolution efficiency.

Benefits of technology

The automatic shaking and clamping of medicine bottles is realized, which reduces manual operation, improves the efficiency of drug dissolution, reduces the workload of dispensing personnel, and avoids the overturning of medicine bottles and the generation of bubbles.

✦ Generated by Eureka AI based on patent content.

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Abstract

A paclitaxel preparation assist device for injection relates to the field of medical instruments and comprises a base, a placement seat and a clamping mechanism, and a swing shaft is arranged on the base; the placing seat is rotatably arranged on the swinging shaft; the clamping mechanism is arranged on the containing groove and used for clamping the paclitaxel medicine bottle and comprises a clamping jaw, a rotating shaft, a shaft sleeve and a balancing weight, and the clamping jaw rotates around the rotating shaft through the shaft sleeve and can clamp and be attached to the bottom face and the side face of the paclitaxel medicine bottle; the balancing weight is arranged at the top of the outer side of the clamping jaw and can enable the clamping jaw to rotate outwards around the rotating shaft to open the clamping jaw. A medicine bottle to be dissolved is placed in the placing base to swing so as to automatically shake the medicine bottle, the medicine dispensing efficiency is greatly improved, the workload of medicine dispensing personnel is relieved, the device drives the clamping jaws to be closed inwards through the dead weight of the medicine bottle, the medicine bottle is automatically clamped, side turning or overturning of the medicine bottle can be effectively avoided, and the medicine dispensing efficiency is improved. And when the medicine bottle is taken, the clamping jaw can automatically release the medicine bottle only by lifting the medicine bottle upwards, so that the medicine bottle is very convenient to take and place.
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Description

Technical Field

[0001] The utility model belongs to the field of medical devices, in particular to a paclitaxel dispensing aid for injection. Background Art

[0002] Paclitaxel (albumin-bound) for injection is a sterile, lyophilized block or powder before dispersing and dissolving. During preparation, sodium chloride injection must be added before dispersing and dissolving. During preparation, bubbles must be avoided, so vigorous shaking is not recommended. If bubbles occur, the bottle must be left standing for at least 15 minutes to dissipate. Because albumin-bound paclitaxel generally has poor solubility, dispensing often requires the dispenser to gently shake the bottle or slowly invert it for at least two minutes to allow the internal components to fully dissolve. However, dissolution often fails during actual preparation. Due to the large dosage of paclitaxel (albumin-bound) for injection in recent years, preparation requires a large volume, and manual handling typically only allows for two bottles at a time, making preparation time-consuming and labor-intensive, requiring improvement. Utility Model Content

[0003] The purpose of the utility model is to overcome the shortcomings of the prior art and provide a paclitaxel preparation auxiliary device for injection.

[0004] The utility model adopts the following technical solutions:

[0005] A paclitaxel dispensing aid for injection comprises a base, a placement seat and a clamping mechanism, wherein the base is provided with a swing shaft whose axis extends in the horizontal direction; the placement seat is rotatably arranged on the swing shaft and is used to place a paclitaxel medicine bottle; a plurality of clamping mechanisms are provided, which are arranged on a placement groove and are used to clamp the paclitaxel medicine bottle, and comprise clamping jaws, a rotating shaft, a shaft sleeve and a counterweight block, wherein the clamping jaws are arranged relative to each other and can be fitted to the bottom and side surfaces of the paclitaxel medicine bottle; the rotating shaft is arranged on the placement seat; the shaft sleeve is arranged at the outer bottom of the clamping jaw and can cooperate with the rotating shaft; the counterweight block is arranged at the outer top of the clamping jaw and can cause the clamping jaw to rotate outward around the rotating shaft to open the clamping jaw, and after the bottom of the paclitaxel medicine bottle contacts the clamping jaw, the clamping jaw rotates inward under the action of gravity to close the clamping jaw and clamp the paclitaxel medicine bottle.

[0006] Preferably, the clamp includes a vertical section, a bottom section and a neck section. There are two vertical sections, which extend in the vertical direction and can be attached to the side of the medicine bottle; the bottom section is vertically connected between the bottoms of the two vertical sections, and the top surface of the bottom section can contact the bottom of the medicine bottle; the neck section is vertically connected between the tops of the two vertical sections, and the neck section can cooperate with the neck of the medicine bottle as the clamp closes.

[0007] Preferably, the clamp also includes a first connecting section and a second connecting section, the first connecting section and the second connecting section are connected between the two vertical sections and can contact the side of the bottle body of the medicine bottle, the first connecting section is located close to the bottom section, and the sleeve is arranged on the first connecting section to cooperate with the rotating shaft; the second connecting section is located close to the neck section, and the counterweight block is arranged on the second connecting section to make the center of gravity of the clamp shift outward.

[0008] Preferably, the base includes a base plate, a side plate vertically arranged on one side of the base plate, a sliding groove extending downward from the top surface of the side plate, and a lifting rod that can be lifted and lowered in the sliding groove, and the swing shaft is arranged on the lifting rod.

[0009] Preferably, it also includes an up and down oscillation mechanism provided on the base and connected to the lifting rod, the up and down oscillation mechanism includes a give way groove, a cam and a driving handle, the give way groove is formed in the side plate and is located below the sliding groove, the top surface of the give way groove is connected to the bottom surface of the sliding groove; the cam is rotatably provided in the give way groove around an axis perpendicular to the side plate, the bottom surface of the lifting rod contacts the cam and moves up and down as the cam rotates; the driving handle is provided on the side plate and connected to the cam and can drive the cam to rotate.

[0010] Preferably, limiting rods for limiting the rotation range of the placement seat are further provided on both sides of the side panels.

[0011] Preferably, a limiting plate is also provided on the placement seat, which is provided on the placement seat and has a height higher than the height of the rotating shaft. A plurality of limiting holes corresponding to the clamping mechanism are formed on the limiting plate, and the clamping claw can be supported on the side of the limiting hole after rotating outward.

[0012] From the above description of the utility model, it can be seen that compared with the prior art, the beneficial effects of the utility model are as follows: the medicine bottle to be dissolved is placed in the placement seat, the placement seat is pushed to one side and then released, and the placement seat swings under the action of its own gravity to automatically complete the shaking of the medicine bottle. The dispensing staff only needs to keep the placement seat swinging continuously, which greatly improves the dispensing efficiency and reduces the workload of the dispensing staff. In addition, the device drives the clamping claws to close inward by the weight of the medicine bottle, automatically completes the clamping of the medicine bottle, and can effectively prevent the medicine bottle from tipping over or overturning. When taking it out, you only need to lift the medicine bottle up, and the clamping claws will automatically release the medicine bottle, which is extremely convenient for taking and placing.

[0013] The special structure of the clamp allows the vertical section, bottom section and neck section to contact the side, bottom and neck of the medicine bottle respectively when closed, so that the clamp can completely fit the medicine bottle, further improving the clamping stability of the clamp;

[0014] The center of gravity of the clamp is offset by the counterweight, so that the clamp can be opened by its own gravity in the idle state, without manual separation of the clamp, which is very practical.

[0015] The cam drives the lifting rod to move up and down, which can assist the placement seat to move up and down to complete the oscillation of the medicine bottle, so that the device can perform multi-directional medicine bottle oscillation, thereby improving the dissolution efficiency of the medicine in the medicine bottle. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 This is a schematic diagram of the structure of the utility model Figure 1 ;

[0017] Figure 2 This is a schematic diagram of the structure of the utility model Figure 2 ;

[0018] Figure 3 This is a cross-sectional view of the utility model Figure 1 ;

[0019] Figure 4 for Figure 3 A partial enlarged view of point A in the middle;

[0020] Figure 5 This is a cross-sectional view of the utility model Figure 2 ;

[0021] Figure 6 This is a partial enlarged view of the clamping mechanism of the utility model;

[0022] In the figure: 1-base; 11-base plate; 12-side plate; 13-sliding groove; 14-lifting rod; 15-swinging shaft; 16-limiting rod; 2-placing seat; 21-limiting plate; 22-limiting hole; 3-clamping mechanism; 31-clamping claw; 311-vertical section; 312-bottom section; 313-neck section; 314-first connecting section; 315-second connecting section; 32-rotating shaft; 33-sleeve; 34-counterweight; 4-up and down oscillation mechanism; 41-giving groove; 42-cam; 43-driving handle. DETAILED DESCRIPTION

[0023] The present invention is further described below through specific implementation methods.

[0024] like Figures 1 to 6 As shown, a paclitaxel dispensing aid for injection includes a base 1, a placement seat 2, a clamping mechanism 3, and an up and down oscillation mechanism 4.

[0025] The base 1 includes a base plate 11, a side plate 12 vertically arranged on one side of the base plate 11, a sliding groove 13 extending downward from the top surface of the side plate 12, a lifting rod 14 that can be lifted and lowered in the sliding groove 13, and a swing shaft 15 arranged on the lifting rod 14 and with its axis extending in the horizontal direction.

[0026] A susceptor 2 is rotatably mounted on a swing shaft 15 and is used to hold a paclitaxel vial. The vial to be dissolved is placed in susceptor 2, which is then pushed to one side and released. Susceptor 2 swings under its own weight, automatically shaking the vial. Dispensers only need to keep susceptor 2 swinging, significantly improving dispensing efficiency and reducing their workload.

[0027] The clamping mechanism 3 is provided with several parts and is arranged on the placement slot for clamping the paclitaxel bottle. The clamping mechanism 3 includes a clamping jaw 31, a rotating shaft 32, a sleeve 33, and a counterweight 34. The clamping jaws 31 are arranged relative to each other and can be attached to the bottom and side surfaces of the paclitaxel bottle. The rotating shaft 32 is arranged on the placement seat 2. The sleeve 33 is arranged at the bottom outside the clamping jaw 31 and can cooperate with the rotating shaft 32. The counterweight 34 is arranged at the top outside the clamping jaw 31 and can rotate the clamping jaw 31 outward about the rotating shaft 32 to open the clamping jaw 31. After the bottom of the paclitaxel bottle contacts the clamping jaw 31, the clamping jaw 31 rotates inward under the action of gravity to close the clamping jaw 31 and clamp the paclitaxel bottle. The counterweight 34 offsets the center of gravity of the clamping jaw 31, so that the clamping jaw 31 can be opened by its own gravity when idle, eliminating the need for manual separation of the clamping jaw 31, thus improving practicality. The weight of the medicine bottle drives the clamping jaws 31 to close inward, automatically clamping the medicine bottle, which can effectively prevent the medicine bottle from tipping over or overturning. When taking the medicine bottle, you only need to lift the medicine bottle upwards, and the clamping jaws 31 will automatically release the medicine bottle, making it extremely convenient to take and place the medicine bottle.

[0028] The top of the fixing plate 312 is provided with a fixing piece 314 and a fixing piece 315, and the fixing piece 314 is fixed to the fixing plate 312 by the fixing piece 316. Due to the special structure of the clamp 31, when closed, the vertical section 311, the bottom section 312 and the neck section 313 are in contact with the side, bottom and neck of the medicine bottle respectively. The clamp 31 can completely fit the medicine bottle, further improving the clamping stability of the clamp 31.

[0029] Furthermore, a limiting plate 21 is provided on the placement seat 2. The limiting plate 21 is provided on the placement seat 2 and its height is higher than the height of the rotating shaft 32. A plurality of limiting holes 22 corresponding to the clamping mechanism 3 are formed on the limiting plate 21. The clamping claw 31 can be supported on the side of the limiting hole 22 after rotating outward.

[0030] The up-and-down oscillation mechanism 4 is disposed on the base 1 and connected to the lifting rod 14. The up-and-down oscillation mechanism 4 includes a clearance groove 41, a cam 42, and a driving handle 43. The clearance groove 41 is formed in the side panel 12 and located below the sliding groove 13. The top surface of the clearance groove 41 is connected to the bottom surface of the sliding groove 13. The cam 42 is rotatably disposed in the clearance groove 41 about an axis perpendicular to the side panel 12. The bottom surface of the lifting rod 14 contacts the cam 42 and moves up and down as the cam 42 rotates. The driving handle 43 is disposed on the side panel 12 and connected to the cam 42 to drive the cam 42 to rotate. The cam 42 drives the lifting rod 14 up and down, assisting the placement seat 2 in moving up and down to complete the oscillation of the medicine bottle. This device can perform multi-directional bottle oscillation and improve the dissolution efficiency of the medicine in the medicine bottle. Specifically, limit rods 16 are also disposed on both sides of the side panel 12 to limit the rotation range of the placement seat 2. This can limit the rotation range of the placement seat 2 and prevent the medicine bottle from tipping over and falling from the placement seat 2 due to excessive rotation.

[0031] During use, the paclitaxel medicine bottle is placed in the limiting hole 22 from top to bottom and falls into the clamping claw 31. Since the clamping claw 31 will open outwards due to its own center of gravity when it is stationary, the bottom surface of the clamping claw 31 is tilted upward. Since the bottom surface of the medicine bottle contacts the bottom section 312 of the clamping claw 31, the bottom section 312 flips downward under the gravity of the medicine bottle, driving the clamping claw 31 to move closer to the center and clamp the medicine bottle. Then the training staff pushes the placement seat 2 to one side until it contacts the limiting rod 16 and releases the placement seat 2. The placement seat 2 performs reciprocating swinging motion under its own gravity (placing the medicine bottle so that the number of left and right medicine bottles on the placement seat 2 is consistent to maintain the weight balance on both sides of the placement seat 2 to avoid affecting the swing). The dispensing staff only needs to intermittently push the placement seat 2 to continue swinging until the substance in the medicine bottle is completely dissolved. After it stops swinging, the medicine bottle can be taken from bottom to top for use. This application greatly improves the efficiency of dispensing, reduces the workload of the dispensing staff, and is convenient and quick to place and take medicine bottles, with great practicality.

[0032] The above description is merely a preferred embodiment of the present invention and therefore cannot be used to limit the scope of implementation of the present invention. In other words, equivalent changes and modifications made according to the scope of the patent application and the contents of the specification of the present invention should still fall within the scope of the present patent.

Claims

1. A paclitaxel injection preparation aid, characterized by: The invention comprises a base, a placement seat and a clamping mechanism, wherein a swing shaft with an axis extending in a horizontal direction is provided on the base; the placement seat can be rotatably arranged on the swing shaft, and is used to place a paclitaxel medicine bottle; a plurality of clamping mechanisms are provided, which are arranged on the placement groove and are used to clamp the paclitaxel medicine bottle, including clamping claws, a rotating shaft, a shaft sleeve and a counterweight block, and the clamping claws are relatively arranged and can be fitted on the bottom and side surfaces of the paclitaxel medicine bottle; the rotating shaft is arranged on the placement seat; the shaft sleeve is arranged at the outer bottom of the clamping claw and can cooperate with the rotating shaft; the counterweight block is arranged at the outer top of the clamping claw and can make the clamping claw rotate outward around the rotating shaft to open the clamping claw, and after the bottom of the paclitaxel medicine bottle contacts the clamping claw, the clamping claw rotates inward under the action of gravity to close the clamping claw and clamp the paclitaxel medicine bottle.

2. The paclitaxel dispensing aid for injection according to claim 1, characterized in that: The clamping jaws include a vertical section, a bottom section and a neck section. There are two vertical sections, which extend in the vertical direction and can be attached to the side of the medicine bottle. The bottom section is vertically connected between the bottoms of the two vertical sections, and the top surface of the bottom section can contact the bottom of the medicine bottle. The neck section is vertically connected between the tops of the two vertical sections, and the neck section can cooperate with the neck of the medicine bottle as the clamping jaws close.

3. The paclitaxel dispensing aid for injection according to claim 2, characterized in that: The clamp also includes a first connecting section and a second connecting section. The first connecting section and the second connecting section are connected between the two vertical sections and can contact the side of the medicine bottle body. The first connecting section is located close to the bottom section, and the sleeve is arranged on the first connecting section to cooperate with the rotating shaft; the second connecting section is located close to the neck section, and the counterweight block is arranged on the second connecting section to make the center of gravity of the clamp shift outward.

4. The paclitaxel dispensing aid for injection according to claim 1, characterized in that: The base includes a base plate, a side plate vertically arranged on one side of the base plate, a sliding groove extending downward from the top surface of the side plate, and a lifting rod that can be lifted and lowered in the sliding groove, and the swing shaft is arranged on the lifting rod.

5. The paclitaxel dispensing aid for injection according to claim 4, characterized in that: The cam is arranged in the groove for rotation, and the bottom surface of the lifting rod is in contact with the cam and moves up and down as the cam rotates. The driving handle is arranged on the side plate and is connected to the cam and can drive the cam to rotate.

6. The paclitaxel dispensing aid for injection according to claim 4, characterized in that: Limiting rods for limiting the rotation range of the placement seat are also provided on both sides of the side plate.

7. The paclitaxel dispensing aid for injection according to claim 1, characterized in that: A limiting plate is also provided on the placement seat. The limiting plate is provided on the placement seat and its height is higher than the height of the rotating shaft. A plurality of limiting holes corresponding to the clamping mechanism are formed on the limiting plate. The clamping claw can be supported on the side of the limiting hole after rotating outward.