Nucleic acid analyzer

Abstract

The utility model provides a nucleic acid analyzer, which comprises an instrument bottom plate and a support plate fixed on the instrument bottom plate, a plunger pipetting part is slidably connected to the side surface of the support plate on the use operation side of the nucleic acid analyzer, and the plunger pipetting part comprises a pipetting assembly plate, the pipetting assembly plate and the supporting plate are arranged in parallel at an interval, the pipetting assembly plate is in threaded connection with a positioning threaded piece, and the positioning threaded piece has a transportation positioning state in which the positioning threaded piece is in threaded fit connection with the supporting plate and an instrument use state in which the positioning threaded piece is disconnected from the supporting plate and is connected with the pipetting assembly plate. According to the utility model, the reliable positioning of the plunger pipetting component with larger weight is realized, and the component is prevented from being damaged during jolting in the transportation process.

Description

Technical Field

[0001] The utility model belongs to the technical field of biological sample processing equipment, and particularly relates to a nucleic acid analyzer. Background Art

[0002] Nucleic acid analyzers enable fully automated nucleic acid detection and analysis and are currently widely used in the medical field. Nucleic acid analyzers are equipped with a pipette gun assembly, which is used to quantitatively transfer and mix samples from the sample tube array with the various reagents in the test kit, thereby completing the entire nucleic acid detection and analysis process. The pipette gun assembly includes a support plate fixed to the instrument base and a plunger pipette component located on the side of the support plate facing the user. The support plate is assembled with a lift drive assembly, which is used to drive the plunger pipette component up and down (i.e., along the vertical Z axis). Due to the heavy weight of the plunger pipette component, it is difficult to position the plunger pipette component solely using the lift drive assembly during instrument transportation or when the instrument is powered off. This is especially true when the lift drive assembly does not utilize a brake motor. The plunger pipette component falls under its own weight, making its position uncontrollable. This is especially true during bumpy transportation, where the plunger pipette component lacks the necessary positioning, resulting in damage to the equipment. Utility Model Content

[0003] Therefore, the technical problem to be solved by the present invention is to provide a nucleic acid analyzer that can reliably position the plunger pipetting component by setting a bolt member that is threadedly connected to the support plate, thereby effectively preventing the analyzer from being damaged due to bumps during transportation when the power is off.

[0004] In order to solve the above problems, the utility model provides a nucleic acid analyzer, including an instrument base plate and a support plate fixed on the instrument base plate, the support plate is located on the side of the use and operation side of the nucleic acid analyzer and is slidably connected to a plunger pipetting component, the plunger pipetting component includes a pipetting assembly plate, the pipetting assembly plate is arranged parallel to the support plate and spaced apart, the pipetting assembly plate is threadedly connected to a positioning threaded member, the positioning threaded member has a transport positioning state threadedly connected to the support plate and an instrument use state disconnected from the support plate and connected to the pipetting assembly plate.

[0005] In some embodiments, the support plate has a threaded hole, and when the positioning screw is in the transport positioning state, the head of the positioning screw is threadedly engaged with the threaded hole.

[0006] In some embodiments, there are two positioning screws, and the two positioning screws are respectively located at the left and right ends of the pipetting assembly plate.

[0007] In some embodiments, the plunger pipetting component also includes a plunger drive motor, which is assembled on the top of the pipetting assembly plate and on the side away from the support plate. The positioning screw is connected to the top area of ​​the pipetting assembly plate, and when the positioning screw is in the transport positioning state, the tail of the positioning screw protrudes to the side of the plunger drive motor away from the pipetting assembly plate.

[0008] In some embodiments, an isolation cover plate is further provided on a side of the plunger pipetting component facing away from the support plate to shield the plunger pipetting component on its back side.

[0009] In some embodiments, the isolation cover plate is assembled on the pipetting assembly plate.

[0010] In some embodiments, a through hole is provided in an area of ​​the isolation cover plate corresponding to the position of the positioning screw, and a diameter of the through hole is not less than a maximum outer diameter of the tail of the positioning screw.

[0011] In some embodiments, a cap is detachably connected to the through hole.

[0012] In some embodiments, the cap is made of rubber.

[0013] In some embodiments, a regular polygonal groove is formed on the tail end surface of the positioning screw.

[0014] The utility model provides a nucleic acid analyzer. When the nucleic acid analyzer is powered off or needs to be moved, the positioning screw is manually connected to the support plate to form a threaded connection. Therefore, during transportation, the plunger pipetting component of the nucleic acid analyzer and the fixed support plate are connected as a whole without relative movement. In other words, the heavier plunger pipetting component is reliably positioned, preventing damage to the component due to bumps during transportation. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 This is a schematic diagram of the internal structure of a nucleic acid analyzer according to an embodiment of the present utility model (the compartment door is in an open state, and the positioning screw is in a transport positioning state);

[0016] Figure 2 for Figure 1 A partial enlarged view of the J in the middle;

[0017] Figure 3 for Figure 1 Left side view (isolation cover omitted).

[0018] The reference numerals indicate:

[0019] 1. Instrument base plate; 2. Support plate; 21. Lifting drive motor; 3. Plunger pipetting component; 31. Pipetting assembly plate; 32. Plunger drive motor; 4. Positioning screws; 5. Isolation cover plate; 6. Instrument housing; 61. Sealing door; 7. Platform assembly. DETAILED DESCRIPTION

[0020] See also Figures 1 to 3 As shown, according to an embodiment of the present utility model, a nucleic acid analyzer is provided, including an instrument base plate 1, an instrument housing 6 is provided on the instrument base plate 1, a component accommodating space is formed between the instrument housing 6 and the instrument base plate 1, and the instrument housing 6 is also provided with a sealing door 61 capable of opening or closing the aforementioned component accommodating space, a platform assembly 7 is provided in the component accommodating space, and relevant reagent kits and pipes for nucleic acid analysis are placed on the platform assembly 7, a support plate 2 is further fixed on the instrument base plate 1, a lifting drive motor 21 is fixedly connected to the support plate 2, a plunger pipetting component 3 is slidably connected to the side of the support plate 2 on the operating side of the nucleic acid analyzer, the lifting drive motor 21 is used to drive the plunger pipetting component 3 to rise and fall as a whole, and the plunger pipetting component 3 includes a pipetting unit. The liquid assembly plate 31 is arranged parallel to the support plate 2 and spaced apart. The pipetting assembly plate 31 is threadedly connected with a positioning screw 4. The positioning screw 4 has a transport positioning state that is threadedly connected to the support plate 2 and an instrument use state that is disconnected from the support plate 2 and connected to the pipetting assembly plate 31. Specifically, during the use of the nucleic acid analyzer, the aforementioned positioning screw 4 should be in its use state. At this time, there is no connection relationship between the support plate 2 and the positioning screw 4. The positioning screw 4 can rise and fall with the rise and fall of the plunger pipetting component 3. When the nucleic acid analyzer is powered off and needs to be transferred to the use position, the positioning screw 4 needs to be switched to the transport positioning state to ensure that the pipetting assembly plate 31 is fixed at the target height position of the support plate 2.

[0021] In this technical solution, when the nucleic acid analyzer loses power or needs to be relocated, the positioning threaded member 4 is manually threadedly engaged with the support plate 2. This ensures that the plunger pipetting component 3 and the fixed support plate 2 are connected as a single unit during transport, preventing relative movement. This ensures that the heavier plunger pipetting component 3 is securely positioned, preventing damage to the component during bumpy transport. It is important to emphasize that the present invention utilizes a positioning threaded member 4, such as a bolt, to reliably position the plunger pipetting component 3 during transport, eliminating the need for a brake lock function on the corresponding lift drive motor 21, significantly reducing the instrument's manufacturing cost.

[0022] In some embodiments, the support plate 2 has a threaded hole (not marked in the figure). When the positioning screw 4 is in the transport positioning state, the head thread of the positioning screw 4 is connected to the threaded hole, which can ensure the positioning reliability of the positioning screw 4.

[0023] In a preferred embodiment, there are two positioning screw members 4, and the two positioning screw members 4 are respectively located at the left and right ends of the pipetting assembly plate 31, so that the two ends of the pipetting assembly plate 31 can be positioned simultaneously. This technical design is especially for the pipetting assembly plate 31 with a larger width, and can prevent deformation or positioning failure caused by excessive stress caused by single-point positioning.

[0024] In some embodiments, the plunger pipetting component 3 also includes a plunger drive motor 32, which is assembled on the top of the pipetting assembly plate 31 and away from the side of the support plate 2, and the positioning screw 4 is connected to the top area of ​​the pipetting assembly plate 31, and when the positioning screw 4 is in the transport positioning state, the tail of the positioning screw 4 protrudes to the side of the plunger drive motor 32 away from the pipetting assembly plate 31.

[0025] In this technical solution, the tail of the aforementioned positioning screw 4 protrudes to the side of the plunger drive motor 32 away from the pipetting assembly plate 31, that is, the positioning screw 4 can be close to the operating side, which is beneficial for the operator to switch the state of the positioning screw 4, and also facilitates the operator to lock and unlock the pipetting assembly plate 31.

[0026] In a preferred embodiment, an isolation cover plate 5 is further provided on the side of the plunger pipetting component 3 facing away from the support plate 2 to shield the plunger pipetting component 3 from its back. The isolation cover plate 5 can be a sheet metal part, or an injection molded part. By providing the isolation cover plate 5, the plunger pipetting component 3 can be shielded from its back, making the interior of the instrument more tidy. In a specific embodiment, the isolation cover plate 5 is assembled on the pipetting assembly plate 31 and can rise and fall with the rise and fall of the pipetting assembly plate 31.

[0027] As a preferred embodiment, the isolation cover plate 5 is provided with a through hole (not shown in the figure, not labeled) in the area corresponding to the position of the positioning screw 4. The aperture of the through hole is not less than the maximum outer diameter of the tail of the positioning screw 4, so that when the state of the positioning screw 4 needs to be switched, there is no need to remove the isolation cover plate 5 from the pipetting assembly plate 31, which is more convenient. At this time, it is best that a cap (not shown in the figure) is detachably connected to the through hole, so that the corresponding through hole can be sealed with the cap after the operation of the positioning screw 4 is completed, thereby improving the appearance consistency of the instrument. The material of the aforementioned cap is preferably rubber, which has a certain elastic deformation ability and can be embedded in the through hole by relying on its own elastic force.

[0028] In a specific embodiment, the tail end face of the positioning screw 4 has a regular polygonal groove, such as a regular hexagonal groove, so that the state thereof can be switched using a conventional hexagonal tool.

[0029] It is easy for those skilled in the art to understand that, under the premise of no conflict, the above-mentioned advantageous methods can be freely combined and superimposed.

[0030] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent replacements, and improvements made within the spirit and principles of the present invention shall be included within the scope of protection of the present invention. The above are only preferred embodiments of the present invention. It should be noted that for those skilled in the art, several improvements and variations can be made without departing from the technical principles of the present invention, and such improvements and variations shall also be considered within the scope of protection of the present invention.

Claims

1. A nucleic acid analyzer, characterized in that: The invention comprises an instrument base plate (1) and a support plate (2) fixed on the instrument base plate (1); the support plate (2) is slidably connected to a plunger pipetting component (3) on the side of the use operation side of the nucleic acid analyzer; the plunger pipetting component (3) comprises a pipetting assembly plate (31); the pipetting assembly plate (31) is arranged parallel to and spaced apart from the support plate (2); the pipetting assembly plate (31) is threadedly connected to a positioning screw member (4); the positioning screw member (4) has a transport positioning state in which it is threadedly connected to the support plate (2) and an instrument use state in which it is disconnected from the support plate (2) and connected to the pipetting assembly plate (31).

2. The nucleic acid analyzer according to claim 1, characterized in that The support plate (2) has a threaded hole, and when the positioning screw member (4) is in the transport positioning state, the head of the positioning screw member (4) is threadedly connected in the threaded hole.

3. The nucleic acid analyzer according to claim 1, characterized in that There are two positioning screw members (4), and the two positioning screw members (4) are respectively located at the left and right ends of the pipetting assembly plate (31).

4. The nucleic acid analyzer according to claim 1, characterized in that The plunger pipetting component (3) further includes a plunger drive motor (32), which is assembled on the top of the pipetting assembly plate (31) and on a side away from the support plate (2). The positioning screw (4) is connected to the top area of ​​the pipetting assembly plate (31), and when the positioning screw (4) is in the transport positioning state, the tail of the positioning screw (4) protrudes to the side of the plunger drive motor (32) away from the pipetting assembly plate (31).

5. The nucleic acid analyzer according to claim 4, characterized in that An isolation cover plate (5) is further provided on the side of the plunger transfer component (3) facing away from the support plate (2) to shield the plunger transfer component (3) on its back side.

6. The nucleic acid analyzer according to claim 5, characterized in that The isolation cover plate (5) is assembled on the pipetting assembly plate (31).

7. The nucleic acid analyzer according to claim 5, characterized in that A through hole is provided in an area of ​​the isolation cover plate (5) corresponding to the position of the positioning screw member (4), and the aperture of the through hole is not less than the maximum outer diameter of the tail of the positioning screw member (4).

8. The nucleic acid analyzer according to claim 7, characterized in that A cover cap is detachably connected to the through hole.

9. The nucleic acid analyzer according to claim 8, characterized in that The material of the cap is rubber.

10. The nucleic acid analyzer according to claim 5, characterized in that: The tail end surface of the positioning screw member (4) is provided with a regular polygonal groove.

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