Cryopreservation cooling box for organoid transfer

By designing a freezing and cooling box, the problem of organoids being unable to independently maintain low temperatures during transportation is solved, and independent low-temperature environmental protection is provided to ensure the physiological characteristics of organoids during transportation.

CN223356395UActive Publication Date: 2025-09-19上海礼升生物科技有限公司
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Patent Information

Application Number
CN202422433238.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-09
Publication Date
2025-09-19
Estimated Expiration
2034-10-09

AI Technical Summary

Technical Problem

Existing organoid transport boxes cannot maintain a low-temperature environment independently and require additional equipment, making them inconvenient to use.

Method used

A cryopreservation cooling box for organoid transfer was designed, which includes a box body, a lid, an insulation liner and a cooling tank. The liner is filled with dry ice and kept sealed by a locking structure. Insulation materials and temperature-insulating screens are used to maintain a low-temperature environment.

Benefits of technology

It enables low-temperature preservation of organoids during transportation, avoids problems in subsequent use, and provides independent low-temperature environment protection.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of organoid transfer, and discloses a cryopreservation cooling box for organoid transfer, which comprises a box body, a box cover and a storage cylinder, the box body is integrally of a square structure, and the box cover is arranged on the upper portion of the box body in a matched mode; a heat preservation inner container is arranged in the box body, a storage groove is formed in the middle of the heat preservation inner container, and the storage cylinder is arranged in the storage groove. A cooling groove is formed in the portion, on the periphery of the storage groove, of the heat preservation inner container, the cooling groove is filled with dry ice, and a baffle is arranged at the position of a groove opening of the cooling groove. The box cover is connected with one side of the box body through a hinge, a locking block is arranged on the other side of the box cover, and a locking piece is arranged on the lower portion of the locking block. A lock seat is correspondingly arranged on the box body, and the lock plate is correspondingly clamped with the lock seat; according to the cooling box provided by the utility model, the organoid can be protected in a low-temperature environment in the transfer process, so that the organoid is prevented from going wrong in the subsequent use process.
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Description

Technical Field

[0001] The utility model relates to the technical field of organoid transportation, and more specifically, to a cryopreservation cooling box for organoid transportation. Background Art

[0002] Organoids are miniature organs that closely resemble their original tissues or organs in structure and function. They are typically created using 3D bioprinting or self-tissue engineering techniques. Organoids can be used in areas such as research on human diseases, drug testing, and tissue engineering. Organoids can help scientists better understand the mechanisms of human disease, thereby providing new ideas and approaches for disease prevention and treatment. Organoids can also be used in drug testing to assess the safety and efficacy of new drugs. Finally, organoids can be used in tissue engineering to repair damaged tissues and organs.

[0003] During transport, organoids need to be kept in a low-temperature environment to preserve their physiological properties for subsequent use. Existing transport boxes are simple box structures that require additional equipment to maintain their low-temperature environment and cannot be used independently, causing inconvenience. Utility Model Content

[0004] In order to overcome the shortcomings of the existing technology, the utility model provides a cryopreservation cooling box for organoid transfer, which has the advantage of more precise operation.

[0005] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: A cryopreservation cooling box for organoid transfer, characterized in that it includes: a box body, a box lid, and a storage tube, the box body as a whole is a square structure, and a box lid is arranged on the upper part of the box body; an insulation liner is arranged inside the box body, a storage slot is arranged in the middle position of the insulation liner, and the storage tube is arranged in the storage slot; a cooling slot is arranged on the insulation liner around the storage slot, the cooling slot is filled with dry ice, and a baffle is arranged at the slot position of the cooling slot; the box lid is connected to one side of the box body by a hinge, and a locking block is arranged on the other side of the box lid, and a locking plate is arranged at the lower part of the locking block; a lock seat is correspondingly arranged on the box body, and the locking plate is correspondingly engaged with the lock seat.

[0006] As a preferred technical solution of the present invention, a pin seat is provided on the outside of the lock seat, a bayonet is provided in the pin seat, and the bayonet passes through the lock seat and is engaged with the lock plate.

[0007] As a preferred technical solution of the present invention, the thermal insulation liner is made of thermal insulation material, and a circle of thermal insulation screen is provided at the position where the thermal insulation liner is close to the inner wall of the box body.

[0008] As an optimal technical solution of the present invention, the storage tank is a cylindrical sink, the cooling tank is arc-shaped as a whole, and the cooling tank is distributed in a circular array around the storage tank; the storage cylinder is a cylindrical cylinder, and a cylinder cover is installed at the cylinder mouth of the storage cylinder.

[0009] As an optimal technical solution of the present invention, a pad is provided in the storage groove, and the lower part of the pad is sleeved on the stud at the center of the storage groove through a screw barrel; a handle is provided on the upper part of the box cover, and the handle is a C-shaped structure.

[0010] As a preferred technical solution of the present invention, a sleeve is provided on the upper portion of the baffle, an elastic rod is connected to the sleeve via a spring, and a pressure plate is installed on the elastic rod.

[0011] As a preferred technical solution of the present invention, a buffer pad is provided on the pressure plate, and the buffer pad is composed of a plurality of groups of concentric ring-shaped rubber pads.

[0012] Compared with the existing technology, the beneficial effects of the present invention are as follows: the cooling box provided by the present invention achieves a low-temperature environment by setting a cooling tank and filling the tank with dry ice, and is insulated by an insulating liner; it can protect organoids in a low-temperature environment during transportation, thereby avoiding problems with the organoids in subsequent use. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 This is a schematic diagram of the structure of the utility model;

[0014] Figure 2 This is a schematic diagram of the interior of the box body of the utility model;

[0015] Figure 3 This is a schematic diagram of the box structure of the utility model;

[0016] Figure 4 This is a schematic diagram of the assembly of the box body, storage tube, and baffle of the utility model;

[0017] Figure 5 This is a schematic diagram of the cylinder cover structure of the utility model;

[0018] In the figure: 1. Box body; 11. Insulated liner; 12. Insulated screen; 13. Lock seat; 14. Cooling tank; 15. Storage tank; 16. Pad; 2. Box cover; 21. Handle; 22. Lock block; 23. Locking plate; 3. Storage cylinder; 31. Cylinder cover; 4. Baffle; 41. Sleeve; 42. Spring rod; 43. Pressure plate; 44. Buffer pad; 5. Pin seat; 51. Lock pin. DETAILED DESCRIPTION

[0019] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0020] like Figures 1 to 4 As shown, the utility model provides a cryopreservation cooling box for organoid transfer, characterized in that it includes: a box body 1, a box lid 2, and a storage tube 3. The box body 1 is a square structure as a whole, and the box lid 2 is cooperated with the upper part of the box body 1; an insulation liner 11 is provided inside the box body 1, and a storage slot 15 is provided in the middle position of the insulation liner 11, and the storage tube 3 is provided in the storage slot 15; a cooling slot 14 is provided on the insulation liner 11 around the storage slot 15, and the cooling slot 14 is filled with dry ice, and a baffle 4 is provided at the notch position of the cooling slot 14; the box lid 2 is connected to one side of the box body 1 by a hinge, and a locking block 22 is provided on the other side of the box lid 2, and a locking plate 23 is provided at the lower part of the locking block 22; a lock seat 13 is correspondingly provided on the box body 1, and the locking plate 23 is correspondingly engaged with the lock seat 13.

[0021] The storage tube 3 is used to store organoids that need to be transported. The storage tube 3 is placed in the storage tank 15 and is surrounded by the thermal insulation liner 11. The cooling tank 14 is filled with dry ice to achieve cooling, so that the organoids can be transported in a low-temperature environment.

[0022] A pin seat 5 is provided on the outer side of the lock seat 13 , and a latch pin 51 is provided in the pin seat 5 . The latch pin 51 passes through the lock seat 13 and is latched with the lock piece 23 .

[0023] The latch 51 in the pin seat 5 passes through the lock seat 13 and engages with the lock piece 23 , so that when the box cover 2 is closed, the latch can be kept in place, the internal environment is sealed, and the low temperature environment inside is maintained.

[0024] The heat-insulating inner liner 11 is made of heat-insulating material, and a circle of heat-insulating screen 12 is provided at the position where the heat-insulating inner liner 11 is close to the inner wall of the box body 1 .

[0025] The thermal insulation material can be thermal insulation sponge, thermal insulation foam and other materials. On the one hand, they have good thermal insulation performance, which is conducive to maintaining the internal low-temperature environment. On the other hand, they can also play a buffering role; the thermal insulation screen 12 is used to assist in the thermal insulation effect.

[0026] Among them, the storage tank 15 is a cylindrical sink, the cooling tank 14 is arc-shaped as a whole, and the cooling tank 14 is distributed in a ring array around the storage tank 15; the storage cylinder 3 is a cylindrical cylinder, and a cylinder cover 31 is installed at the cylinder mouth of the storage cylinder 3.

[0027] The annularly distributed cooling grooves 14 can evenly cool the storage tank 15 so that the storage tank 15 is cooled evenly.

[0028] A pad 16 is provided in the storage groove 15 , and the lower portion of the pad 16 is sleeved on the stud at the center of the storage groove 15 through a screw barrel; a handle 21 is provided on the upper portion of the box cover 2 , and the handle 21 is a C-shaped structure.

[0029] The height of the backing plate 16 can be adjusted by means of a thread, thereby adjusting the height to a suitable height for taking out and placing the storage tube 3 for easy use; the provision of the handle 21 facilitates lifting the entire cooling box.

[0030] Among them, the baffle 4 is provided with a sleeve 41 on the upper part, and the sleeve 41 is connected to the elastic rod 42 through a spring, and the elastic rod 42 is installed with a pressure plate 43. The pressure plate 43 is provided with a buffer pad 44, which is composed of several groups of concentric ring-shaped rubber pads.

[0031] The baffle 4 mainly covers the cooling tank 14. After the box cover 2 is closed, the inner wall of the box cover 2 is released from the pressure plate 43, and the spring rod 42 connected by the spring presses the baffle 4 to press the dry ice in the tank; the buffer pad 44 on the pressure plate 43 plays a buffering and protective role.

[0032] It should be noted that, in this document, relational terms such as first and second, etc., are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that includes a list of elements includes not only those elements but also other elements not explicitly listed, or elements inherent to such process, method, article, or apparatus.

[0033] Although the embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations may be made to these embodiments without departing from the principles and spirit of the present invention, and the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A cryopreservation cooling box for organoid transfer, characterized in that: The invention comprises: a box body (1), a box cover (2), and a storage tube (3); the box body (1) is in a square structure as a whole, and the box cover (2) is arranged on the upper part of the box body (1); a heat preservation liner (11) is arranged inside the box body (1), a storage groove (15) is arranged in the middle position of the heat preservation liner (11), and the storage tube (3) is arranged in the storage groove (15); a cooling groove (14) is arranged on the heat preservation liner (11) around the storage groove (15), the cooling groove (14) is filled with dry ice, and a baffle (4) is arranged at the notch position of the cooling groove (14); the box cover (2) is connected to one side of the box body (1) through a hinge, and a locking block (22) is arranged on the other side of the box cover (2), and a locking plate (23) is arranged at the lower part of the locking block (22); a lock seat (13) is correspondingly arranged on the box body (1), and the locking plate (23) is correspondingly engaged with the lock seat (13).

2. The cryopreservation cooling box for organoid transfer according to claim 1, characterized in that: A pin seat (5) is provided on the outside of the lock seat (13), a latch pin (51) is provided in the pin seat (5), and the latch pin (51) passes through the lock seat (13) and is latched with the lock plate (23).

3. The cryopreservation cooling box for organoid transfer according to claim 1, characterized in that: The heat-insulating inner liner (11) is made of heat-insulating material, and a circle of heat-insulating screen (12) is provided at a position where the heat-insulating inner liner (11) is attached to the inner wall of the box body (1).

4. The cryopreservation cooling box for organoid transfer according to claim 1, characterized in that: The storage tank (15) is a cylindrical sink, the cooling tank (14) is arc-shaped as a whole, and the cooling tanks (14) are distributed in a ring array around the storage tank (15); the storage cylinder (3) is a cylindrical cylinder, and a cylinder cover (31) is installed at the cylinder mouth of the storage cylinder (3).

5. The cryopreservation cooling box for organoid transfer according to claim 1, characterized in that: A pad (16) is provided in the storage groove (15), and the lower portion of the pad (16) is sleeved on the stud at the center of the storage groove (15) through a screw barrel; a handle (21) is provided on the upper portion of the box cover (2), and the handle (21) is a C-shaped structure.

6. The cryopreservation cooling box for organoid transfer according to claim 1, characterized in that: A sleeve (41) is provided on the upper portion of the baffle (4), a spring rod (42) is connected to the sleeve (41) via a spring, and a pressure plate (43) is mounted on the spring rod (42).

7. The cryopreservation cooling box for organoid transfer according to claim 6, characterized in that: A buffer pad (44) is provided on the pressure plate (43), and the buffer pad (44) is composed of a plurality of groups of concentric ring-shaped rubber pads.