Automatic liquid mixing pipette

Abstract

The utility model discloses an automatic liquid mixing pipette which comprises a gun body, and the lower end of the gun body is connected with a gun barrel assembly; a gas path switching assembly is arranged on the gun barrel assembly; an inner gun head is arranged at the lower end of the gun barrel assembly and used for primary liquid taking, and an outer gun head is arranged outside the inner gun head and used for secondary liquid taking. Compared with the prior art, the utility model has the advantages that the steps of sampling and matrix mixing can be saved, the liquid can be premixed in the gun head and directly dropped on the target plate, the sample preparation is convenient, the sample preparation speed is improved, the step of mixing in a centrifugal tube is eliminated, and the use of consumables is reduced.

Description

Technical Field

[0001] The utility model relates to the technical field of liquid-mixing pipettes, in particular to an automatic liquid-mixing pipette. Background Art

[0002] A pipette, also known as a liquid pipette, is a precision liquid measuring tool commonly used in laboratories. It controls the volume of liquid drawn in and out by adjusting the position of a piston. When the pipette's button is pressed, the piston moves downward, expelling air and creating negative pressure, which allows the liquid to be drawn in. When the button is released, the piston moves upward, pushing the liquid out.

[0003] During the experiment, the dry spot method is a commonly used sample preparation method for MALDI-TOF. It requires mixing the sample and matrix in proportion, and then dropping the mixture onto the target plate to dry naturally. This requires that the sample and matrix be evenly mixed before pipetting. The steps are relatively cumbersome, which increases the overall experimental time and reduces the efficiency of the experiment. Utility Model Content

[0004] The purpose of the present utility model is to solve the above problems and provide an automatic liquid mixing pipette gun.

[0005] In order to achieve the above-mentioned purpose, the present invention specifically adopts the following technical solutions:

[0006] An automatic liquid mixing pipette gun comprises a gun body, wherein the lower end of the gun body is connected to a gun barrel assembly;

[0007] The barrel assembly is provided with an air path switching assembly;

[0008] An inner gun head is provided at the lower end of the barrel assembly, and the inner gun head is used for taking liquid once. An outer gun head is provided outside the inner gun head, and the outer gun head is used for taking liquid twice. The inner gun head is used to mix the liquid taken once with the liquid taken twice.

[0009] As a further description of the above technical solution, a protrusion is formed on the surface of the barrel assembly, and the air path switching assembly includes a valve core extending into and passing through the protrusion. A second air path is opened inside the protrusion, and the second air path is connected to the atmosphere. The valve core switches its position in the tube cavity of the barrel assembly and the second air path.

[0010] As a further description of the above technical solution, the shape of the valve core is adapted to the shape of the lumen.

[0011] As a further description of the above technical solution, the valve core is connected to an external button through a valve stem, and the button and the protrusion are connected through a reset member.

[0012] As a further description of the above technical solution, the outer gun head is sleeved on the outside of the inner gun head, and the bottom of the inner gun head is a thin tube.

[0013] As a further description of the above technical solution, the upper end of the outer gun head and the lower end of the inner gun head are interference fit.

[0014] As a further description of the above technical solution, a mixing chamber is provided on the top of the inner gun head, and the mixing chamber is used to mix the liquid after the second liquid extraction.

[0015] As a further description of the above technical solution, the mixing chamber is a hollow spherical structure.

[0016] As a further description of the above technical solution, the outer gun head is arranged at the lower end of the mixing chamber

[0017] The beneficial effects of the utility model are as follows:

[0018] 1. Compared with the existing technology, the utility model can save the steps of sampling and matrix mixing. The liquid can be pre-mixed in the gun tip and directly applied to the target plate, which is convenient for sample preparation, improves the sample preparation speed, eliminates the step of mixing in the centrifuge tube, and reduces the use of consumables.

[0019] In order to more clearly illustrate the structural features and functions of the present invention, the present invention will be described in detail below with reference to the accompanying drawings and specific embodiments. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 is a schematic diagram of an automatic liquid mixing pipette;

[0021] Figure 2 It is an enlarged schematic diagram of the gas path switching component;

[0022] Figure 3 It is a schematic diagram of the cooperation between the inner gun head and the outer gun head.

[0023] Figure numerals: 1. gun body; 2. barrel assembly; 3. air path switching assembly; 301. protrusion; 302. valve core; 303. valve stem; 304. button; 305. second air path; 306. reset element; 307. lumen; 4. inner gun head; 5. outer gun head; 6. mixing chamber. DETAILED DESCRIPTION

[0024] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention.

[0025] like Figure 1-Figure 3As shown, in one embodiment, an automatic liquid mixing pipette includes a gun body 1, a barrel assembly 2 is connected to the lower end of the gun body 1, an air path switching assembly 3 is provided on the barrel assembly 2, and an inner gun head 4 is connected to the lower end of the barrel assembly 2. In this embodiment, the inner gun head 4 is used for the first liquid extraction, and an outer gun head 5 is also sleeved on the outside of the inner gun head 4, wherein the outer gun head 5 is used for the second liquid extraction, and the inner gun head is used to mix the liquid after the first liquid extraction with the liquid after the second liquid extraction.

[0026] When in use, after pressing the control button on the upper end of the gun body 1, the pipette with the inner gun head 4 is inserted into the first liquid to be sucked, and then the control button is released to allow the liquid to be sucked into the inner gun head 4. The outer gun head 5 is sleeved on the outside of the inner gun head 4. The inner cavity of the barrel assembly 2 is connected to the external atmosphere by controlling the air circuit switching component 3. At this time, the control button is pressed again, and the pipette equipped with the outer gun head 5 is inserted into the second liquid to be sucked, the external air circuit is closed and the control button is released to suck the liquid for the second time. Then, the inner cavity of the barrel assembly 2 is connected to the atmosphere by controlling the air circuit switching component 3. The control button, i.e., the pipette button, is pressed, and the air circuit switching component 3 is controlled to close the external air circuit, and then air is inhaled to make the liquids inhaled twice tumble and mix in the mixing chamber. In some embodiments, air can be inhaled multiple times to mix the liquids evenly, and finally the mixed liquid is discharged. Compared with the prior art, the steps of sampling and matrix mixing can be saved, and the liquid can be premixed in the gun head and directly spotted on the target plate, which is convenient for sample preparation, improves the sample preparation speed, eliminates the step of mixing in the centrifuge tube, and reduces the use of consumables.

[0027] It should be noted that when inhaling air, it is necessary to prevent liquid from entering the interior of the barrel assembly 2. Therefore, the range of the pipette should be smaller than the volume of the mixing chamber and can be adjusted according to actual conditions. When discharging the mixed liquid, the liquid should be at the bottom of the mixing chamber so that the pipette can discharge the mixed liquid at one time.

[0028] Optionally, refer to Figure 2 A protrusion 301 is formed on the surface of the barrel assembly 2, and the gas path switching assembly 3 includes a valve core 302 extending into and passing through the protrusion 301. A second gas path 305 is opened inside the protrusion 301, and the second gas path 305 is connected to the atmosphere. The valve core 302 switches its position between the lumen 307 of the barrel assembly 2 and the second gas path 305. The valve core 302 is connected to an external button 304 through a valve stem 303. The button 304 is connected to the protrusion 301 through a reset member. By pressing the button 304, the valve stem 303 can drive the valve core 302 to move into the lumen 307, thereby keeping the lumen 307 at the lower end of the valve core 302 sealed, and making the lumen 307 at the upper end of the valve core 302 connected to the second gas path 305, thereby preventing the liquid from the first liquid collection from being accidentally discharged during the secondary liquid collection process.

[0029] Optionally, the shape of the valve core 302 matches the shape of the lumen 307 , that is, the cross-section of the lumen 307 is circular, and the shape of the valve core 302 is an oblate cylinder, and the shape of the second gas path 305 is the same as that of the lumen 307 .

[0030] Optionally, the valve core 302 is connected to the external button 304 through the valve stem 303, and the button 304 is connected to the protrusion 301 through a reset member. Before taking liquid for the second time, it is necessary to press the button 304 to block the lower end tube cavity 307 of the valve core 302 through the valve core 302. After releasing the button 304, the reset member can restore the pipette to its original state, making the operation more convenient.

[0031] Optionally, the outer gun tip 5 is sleeved on the outside of the inner gun tip 4, and the bottom of the inner gun tip 4 is a thin tube. The thin tube at the bottom of the inner gun tip 4 can facilitate the absorption of liquid, and the outer gun tip 5 can be used to eliminate contamination of the sample during aspiration.

[0032] Optionally, the upper end of the outer gun head 5 and the lower end of the inner gun head 4 are interference fit, so that the inner gun head 4 and the outer gun head 5 can be tightly combined, which can effectively reduce the outer gun head 5 from falling off during liquid aspiration.

[0033] Optionally, the mixing chamber 6 is a hollow spherical structure. In some embodiments, the mixing chamber 6 may also be a structure of other shapes as long as it can meet the requirements for mixing liquids, which is not limited here.

[0034] The above description of the disclosed embodiments will enable one skilled in the art to implement or use the present invention. Various modifications to these embodiments will be readily apparent to one skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention is not limited to the embodiments shown herein but is intended to conform to the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. An automatic liquid mixing pipette, characterized in that: It comprises a gun body, wherein the lower end of the gun body is connected to a barrel assembly; The barrel assembly is provided with an air path switching assembly; An inner gun head is provided at the lower end of the barrel assembly, and the inner gun head is used for taking liquid once. An outer gun head is provided outside the inner gun head, and the outer gun head is used for taking liquid twice. The inner gun head is used to mix the liquid taken once with the liquid taken twice.

2. The automatic liquid mixing pipette according to claim 1, characterized in that: A protrusion is formed on the surface of the barrel assembly, and the air path switching assembly includes a valve core extending into and passing through the protrusion. A second air path is opened inside the protrusion, and the second air path is connected to the atmosphere. The valve core switches its position in the tube cavity of the barrel assembly and the second air path.

3. The automatic liquid mixing pipette according to claim 2, characterized in that: The shape of the valve core is adapted to the shape of the lumen.

4. The automatic liquid mixing pipette according to claim 2, characterized in that: The valve core is connected to an external button via a valve stem, and the button and the protrusion are connected via a reset member.

5. The automatic liquid mixing pipette according to claim 1, characterized in that: The outer gun head is sleeved on the outside of the inner gun head, and the bottom of the inner gun head is a thin tube.

6. The automatic liquid mixing pipette according to claim 5, characterized in that: The upper end of the outer gun head and the lower end of the inner gun head are interference fit.

7. The automatic liquid mixing pipette according to claim 1, characterized in that: A mixing chamber is provided on the top of the inner gun head, and the mixing chamber is used to mix the liquid after the second liquid extraction.

8. The automatic liquid mixing pipette according to claim 7, characterized in that: The mixing chamber is a hollow spherical structure.

9. The automatic liquid mixing pipette according to claim 7, characterized in that: The outer gun head is arranged at the lower end of the mixing chamber.

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