Eight-channel precise pressure perfusion device

Abstract

The utility model relates to the technical field of pressure perfusion, and discloses an eight-channel precise pressure perfusion device which comprises a loading box, the top wall of the loading box is fixedly connected with a cover plate, the middle of the right side of the inner bottom wall of the loading box is fixedly connected with a pneumatic pump, and the upper end of the pneumatic pump is communicated with an air pipe. A liquid storage tank is fixedly connected to the middle of the inner bottom wall of the loading box, one end of the air pipe communicates with the upper end of the right side of the outer wall of the liquid storage tank, a first water pipe communicates with the middle of the top wall of the liquid storage tank, a plurality of second water pipes communicate with the outer wall of the first water pipe, and connecting pipes are fixedly connected to one ends of the second water pipes; and the front sides of the plurality of connecting pipes are fixedly connected with liquid storage pipes. According to the utility model, liquid can sequentially pass through the air pipe, the liquid storage tank, the water pipe I, the water pipe II, the connecting pipe, the liquid storage pipe and the liquid outlet pipe, so that perfusion operation can be simultaneously carried out on a plurality of samples or a plurality of parts, and the experiment time is greatly saved.

Description

Technical Field

[0001] The utility model relates to the technical field of pressure perfusion, in particular to an eight-channel precise pressure perfusion device. Background Art

[0002] A pressure perfusion device is an experimental device used in the fields of biology and medicine. It consists of a perfusion fluid storage container, a pressure regulation system, piping, and an interface for connecting experimental samples. By applying a certain pressure to the perfusion fluid, it flows through specific biological tissue or organ samples at a set flow rate and direction, so as to study the physiological functions of cells and the effects of drugs.

[0003] In the biological field, pressure perfusion devices play an important role. They can provide continuous nutrients and oxygen supply to isolated tissues, simulate the blood flow environment in the body, promote tissue survival and growth, change the hormone concentration in the perfusion fluid or add specific signaling molecules, and observe the cell response to these changes, thereby revealing the activation and regulatory mechanisms of intracellular signal transduction pathways.

[0004] In existing pressure perfusion devices, because the perfusion channels inside the device are single and small, a single pipeline means that only one perfusion fluid can be delivered or one experimental condition can be set. The need to compare the effects of different perfusion fluids on biological samples or adjust multiple experimental parameters simultaneously will be greatly restricted and increase experimental time. Utility Model Content

[0005] In order to make up for the above shortcomings, the utility model provides an eight-channel precision pressure perfusion device, which aims to improve the problem of insufficient number of pipelines and increased experimental time.

[0006] In order to achieve the above-mentioned purpose, the present invention adopts the following technical scheme: an eight-channel precise pressure perfusion device, comprising a loading box, the top wall of the loading box is fixedly connected to a cover plate, the middle right side of the inner bottom wall of the loading box is fixedly connected to an air pressure pump, the upper end of the air pressure pump is connected to an air pipe, the middle of the inner bottom wall of the loading box is fixedly connected to a liquid storage tank, one end of the air pipe is connected to the upper right side of the outer wall of the liquid storage tank, the middle of the top wall of the liquid storage tank is connected to a water pipe 1, the outer wall of the water pipe 1 is connected to multiple water pipes 2, one end of the multiple water pipes 2 are fixedly connected to a connecting pipe, the front sides of the multiple connecting pipes are fixedly connected to the liquid storage pipe, the bottom sides of the outer walls of the multiple liquid storage pipes are fixedly connected to the liquid outlet pipe, and the middle part of the inner wall of the multiple liquid storage pipes is provided with a rotating mechanism, and the rotating mechanism is used to control the liquid flow rate in the liquid storage pipe.

[0007] As a further description of the above technical solution:

[0008] A rotating mechanism is provided in the middle of the inner wall of the liquid storage tube, and the rotating mechanism includes a rotating plate, the outer wall of the rotating plate is rotatably connected to the middle of the inner wall of the liquid storage tube, the middle upper part of the outer wall of the liquid storage tube is fixedly connected to baffle 1, the middle lower part of the inner wall of the liquid storage tube is fixedly connected to baffle 2, the middle part of the inner wall of the rotating plate is fixedly connected to a rotating rod, the front side of the rotating rod is fixedly connected to a valve, and the middle part of the front side of the valve is threadedly connected to a bolt.

[0009] As a further description of the above technical solution:

[0010] A control panel is fixedly connected to the right side of the top end of the front side of the loading box, and a plurality of buttons are fixedly connected to the front side of the control panel.

[0011] As a further description of the above technical solution:

[0012] A display screen is fixedly connected to the left side of the top end of the front side of the loading box, and the display screen is electrically connected to the operating console.

[0013] As a further description of the above technical solution:

[0014] The tops of the left and right ends of the front side of the loading box are fixedly connected with snap fasteners, and the left and right sides of the front side of the cover plate are fixedly connected with pipe clamps.

[0015] As a further description of the above technical solution:

[0016] A handle is fixedly connected to the front side of the top wall of the cover plate, and ventilation holes are provided on the left and right sides of the loading box.

[0017] As a further description of the above technical solution:

[0018] The four corners of the bottom wall of the loading box are fixedly connected with support columns, and the bottom walls of the plurality of support columns are fixedly connected with anti-slip sleeves.

[0019] As a further description of the above technical solution:

[0020] The left and right sides of the rear top wall of the loading box are fixedly connected with hinges, and the front upper ends of the hinges are fixedly connected to the rear side of the cover plate.

[0021] The utility model has the following beneficial effects:

[0022] 1. In the utility model, when the air pressure pump is working, the gas enters the liquid storage tank through the air pipe. Under the action of pressure, the liquid in the tank is pressed into the water pipe 1, and the liquid can enter multiple water pipes 2. One end of each water pipe 2 is fixedly connected to a connecting pipe, and the front side of the connecting pipe is connected to the liquid storage pipe. The liquid outlet pipe on the bottom side of the outer wall of the liquid storage pipe can output the liquid, thereby realizing the perfusion operation of multiple samples or multiple parts at the same time, greatly saving experimental time.

[0023] 2. In the present invention, by rotating the valve, the rotating rod can be driven to rotate, so that the rotating plate also rotates. During the rotation process, when it is rotated to a certain angle, the baffles 1 and 2 on the liquid storage tube will limit the rotating plate, ensuring that the rotating plate rotates within a specific range, thereby achieving precise control of the liquid flow in the liquid storage tube. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 This is a three-dimensional diagram of an eight-channel precision pressure perfusion device proposed by the present invention;

[0025] Figure 2 This is a rear view of an eight-channel precision pressure perfusion device proposed by the utility model;

[0026] Figure 3 This is a schematic diagram of the structure of an air pressure pump for an eight-channel precision pressure perfusion device proposed in the utility model;

[0027] Figure 4 This is a structural diagram of a water pipe 1 of an eight-channel precision pressure perfusion device proposed by the present invention;

[0028] Figure 5 This is a structural schematic diagram of a rotating plate of an eight-channel precision pressure perfusion device proposed in the utility model.

[0029] Legend:

[0030] 1. Loading box; 2. Rotating mechanism; 201. Rotating plate; 202. Baffle 1; 203. Baffle 2; 204. Rotating rod; 205. Valve; 206. Bolt; 3. Cover; 4. Air pump; 5. Air pipe; 6. Liquid storage tank; 7. Water pipe 1; 8. Water pipe 2; 9. Connecting pipe; 10. Liquid storage pipe; 11. Liquid outlet pipe; 12. Control panel; 13. Button; 14. Display screen; 15. Clip holder; 16. Pipe clamp; 17. Handle; 18. Vent; 19. Support column; 20. Anti-slip cover; 21. Hinge. DETAILED DESCRIPTION

[0031] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0032] Reference Figure 1 、 Figure 3 and Figure 4The utility model provides an embodiment: an eight-channel precision pressure perfusion device, including a loading box 1, a cover plate 3 is fixedly connected to the top wall of the loading box 1, an air pressure pump 4 is fixedly connected to the middle of the right side of the inner bottom wall of the loading box 1, and the upper end of the air pressure pump 4 is connected to an air pipe 5, a liquid storage tank 6 is fixedly connected to the middle of the inner bottom wall of the loading box 1, one end of the air pipe 5 is connected to the upper end of the right side of the outer wall of the liquid storage tank 6, a water pipe 7 is connected to the middle of the top wall of the liquid storage tank 6, and the outer wall of the water pipe 7 is connected to multiple water pipes 8, and one end of the multiple water pipes 8 are all fixedly connected to a connecting pipe 9. The front sides of the multiple connecting tubes 9 are all fixedly connected to the liquid storage tubes 10, and the bottom sides of the outer walls of the multiple liquid storage tubes 10 are all fixedly connected to the liquid outlet tubes 11. Under the pressure of the air pressure pump 4, the gas enters the liquid storage tank 6 through the air pipe 5, so that the liquid inside enters the water pipe 1 7. The liquid can enter the multiple water pipes 2 8 through the water pipe 1 7, thereby realizing the perfusion operation of multiple samples or multiple parts at the same time, greatly saving the experimental time. The middle part of the inner wall of the multiple liquid storage tubes 10 is provided with a rotating mechanism 2, which is used to control the liquid flow rate in the liquid storage tube 10;

[0033] Specifically, the loading box 1 plays an important role in the experiment. Its top wall is fixedly connected to the cover plate 3. An air pressure pump 4 is provided in the middle of the right side of the inner bottom wall. The upper end of the air pressure pump 4 is connected to the air pipe 5, through which the gas is transported to the liquid storage tank 6. The liquid storage tank 6 is fixed in the middle of the inner bottom wall of the loading box 1. When the air pressure pump 4 is working, the gas enters the liquid storage tank 6 through the air pipe 5. Under the action of pressure, the liquid in the tank is pressed into the water pipe 7. The outer wall of the water pipe 7 is connected to multiple water pipes 8, and the liquid can enter There are multiple water pipes 8, one end of each water pipe 8 is fixedly connected to a connecting pipe 9, the front side of the connecting pipe 9 is connected to a liquid storage pipe 10, and the liquid outlet pipe 11 on the bottom side of the outer wall of the liquid storage pipe 10 can output the liquid. This design allows the liquid to pass through the air pipe 5, the liquid storage tank 6, the water pipe 1 7, the water pipe 2 8, the connecting pipe 9, the liquid storage pipe 10 and the liquid outlet pipe 11 in sequence under the pressure of the air pressure pump 4, so that multiple samples or multiple parts can be perfused at the same time, which greatly saves experimental time.

[0034] Reference Figure 1 and Figure 5 A rotating mechanism 2 is provided in the middle of the inner wall of the liquid storage tube 10, and the rotating mechanism 2 includes a rotating plate 201. The outer wall of the rotating plate 201 is rotatably connected to the middle of the inner wall of the liquid storage tube 10. A baffle 1 202 is fixedly connected to the middle upper part of the outer wall of the liquid storage tube 10, and a baffle 203 is fixedly connected to the middle of the inner wall of the liquid storage tube 10. A rotating rod 204 is fixedly connected to the middle of the inner wall of the rotating plate 201. A valve 205 is fixedly connected to the front side of the rotating rod 204. A bolt 206 is threadedly connected to the middle part of the front side of the valve 205. Rotating the valve 205 can drive the rotating rod 204 to rotate, so that the rotating plate 201 can also rotate. When it is turned to a certain angle, the baffle 1 202 and the baffle 2 203 can limit the rotating plate 201.

[0035] Specifically, the outer wall of the rotating plate 201 is rotatably connected to the middle part of the inner wall of the liquid storage tube 10, and the baffle 1 202 is fixed to the middle and upper part of the outer wall of the liquid storage tube 10, and the baffle 203 is fixed to the middle and lower part of the inner wall. The middle part of the inner wall of the rotating plate 201 is connected to the rotating rod 204, and the front side of the rotating rod 204 is fixed with a valve 205. When the valve 205 is rotated, the rotating rod 204 can be driven to rotate, thereby causing the rotating plate 201 to rotate as well. During the rotation process, when it is rotated to a certain angle, the baffle 1 202 and the baffle 2 203 on the liquid storage tube 10 will limit the rotating plate 201, ensuring that the rotating plate 201 rotates within a specific range, thereby achieving effective control of the liquid flow in the liquid storage tube 10.

[0036] Reference Figure 1 and Figure 2 A control panel 12 is fixedly connected to the right side of the front top of the loading box 1. A plurality of buttons 13 are fixedly connected to the front side of the control panel 12 for controlling the machine. A display screen 14 is fixedly connected to the left side of the front top of the loading box 1. The display screen 14 is electrically connected to the control panel 12 for displaying the machine status. Buckle holders 15 are fixedly connected to the tops of the left and right ends of the front of the loading box 1. Pipe clamps 16 are fixedly connected to the left and right sides of the front cover 3 to tightly close the cover 3.

[0037] Specifically, the loading box 1 is practical in design, and a handle 17 is fixed on the front side of the top wall of the cover 3 to facilitate opening the cover 3. Ventilation holes 18 are provided on the left and right sides of the loading box 1 to facilitate heat dissipation. The four corners of the bottom wall of the loading box 1 are fixedly connected to support columns 19, and the bottom wall of each support column 19 is fixedly connected to an anti-slip cover 20. When the machine is started, the anti-slip cover 20 can prevent the loading box 1 from moving. The left and right sides of the rear top wall of the loading box 1 are fixedly connected to hinges 21, and the front upper end of the hinge 21 is connected to the rear side of the cover 3, which also provides convenience for opening the cover 3.

[0038] Reference Figure 1 and Figure 2 , a handle 17 is fixedly connected to the front side of the top wall of the cover 3, and vents 18 are opened on the left and right sides of the loading box 1 to dissipate heat and facilitate opening the cover 3. Support columns 19 are fixedly connected to the four corners of the bottom wall of the loading box 1, and the bottom walls of multiple support columns 19 are fixedly connected with anti-slip sleeves 20 to prevent movement when the machine is started. Hinges 21 are fixedly connected to the left and right sides of the rear top wall of the loading box 1. The front upper end of the hinge 21 is fixedly connected to the rear side of the cover 3 to facilitate opening the cover 3;

[0039] Specifically, a control panel 12 is fixed to the right side of the top front side of the loading box 1. There are multiple buttons 13 on the front side of the control panel 12, which can be used to control the machine. A display screen 14 is fixed to the left side of the top front side of the loading box 1. The display screen 14 is electrically connected to the control panel 12 and can display the status of the machine. In addition, the top of the left and right ends of the front side of the loading box 1 are fixed with snap fasteners 15, and the left and right sides of the front side of the cover plate 3 are fixed with pipe clamps 16. The two can cooperate to close the cover plate 3 tightly to ensure the normal operation of the machine.

[0040] Working principle: The loading box 1 plays an important role in the experiment. Its top wall is fixedly connected to the cover plate 3. An air pressure pump 4 is provided in the middle of the right side of the inner bottom wall. The upper end of the air pressure pump 4 is connected to the air pipe 5, through which the gas is transported to the liquid storage tank 6. The liquid storage tank 6 is fixed in the middle of the inner bottom wall of the loading box 1. When the air pressure pump 4 is working, the gas enters the liquid storage tank 6 through the air pipe 5. Under the action of pressure, the liquid in the tank is pressed into the water pipe 1 7. The outer wall of the water pipe 1 7 is connected to multiple water pipes 2 8, and the liquid can enter through this. Multiple water pipes 8 are provided, one end of each water pipe 8 is fixedly connected to a connecting pipe 9, the front side of the connecting pipe 9 is connected to a liquid storage pipe 10, and a liquid outlet pipe 11 on the bottom side of the outer wall of the liquid storage pipe 10 can output the liquid. This design allows the liquid to pass through the air pipe 5, the liquid storage tank 6, the water pipe 1 7, the water pipe 2 8, the connecting pipe 9, the liquid storage pipe 10 and the liquid outlet pipe 11 in sequence under the pressure of the air pressure pump 4, so that multiple samples or multiple parts can be perfused at the same time, which greatly saves experimental time.

[0041] In addition, the outer wall of the rotating plate 201 is rotatably connected to the middle part of the inner wall of the liquid storage tube 10, and the baffle 1 202 is fixed to the middle and upper part of the outer wall of the liquid storage tube 10, and the baffle 203 is fixed to the middle and lower part of the inner wall. The middle part of the inner wall of the rotating plate 201 is connected to the rotating rod 204, and the front side of the rotating rod 204 is fixed with a valve 205. When the valve 205 is rotated, the rotating rod 204 can be driven to rotate, thereby causing the rotating plate 201 to rotate as well. During the rotation process, when it is rotated to a certain angle, the baffle 1 202 and the baffle 2 203 on the liquid storage tube 10 will limit the rotating plate 201, ensuring that the rotating plate 201 rotates within a specific range, thereby achieving effective control of the liquid flow in the liquid storage tube 10.

[0042] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent replacements for some of the technical features therein. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. An eight-channel precision pressure perfusion device, comprising a loading box (1), characterized in that: The top wall of the loading box (1) is fixedly connected to a cover plate (3), the middle right side of the inner bottom wall of the loading box (1) is fixedly connected to an air pressure pump (4), the upper end of the air pressure pump (4) is connected to an air pipe (5), the middle inner bottom wall of the loading box (1) is fixedly connected to a liquid storage tank (6), one end of the air pipe (5) is connected to the upper right side of the outer wall of the liquid storage tank (6), the middle top wall of the liquid storage tank (6) is connected to a water pipe (7), the water pipe (7) is connected to the upper right side of the outer wall of the liquid storage tank (6), and the water pipe (7) is connected to the upper right side of the outer wall of the liquid storage tank (6). ) is connected to the outer wall of a plurality of water pipes (8), one end of each of the plurality of water pipes (8) is fixedly connected to a connecting pipe (9), the front sides of each of the plurality of connecting pipes (9) are fixedly connected to a liquid storage pipe (10), the bottom sides of the outer walls of each of the plurality of liquid storage pipes (10) are fixedly connected to a liquid outlet pipe (11), and a rotating mechanism (2) is provided in the middle of the inner wall of each of the plurality of liquid storage pipes (10), and the rotating mechanism (2) is used to control the flow rate of the liquid in the liquid storage pipe (10).

2. The eight-channel precision pressure perfusion device according to claim 1, characterized in that: A rotating mechanism (2) is provided in the middle of the inner wall of the liquid storage tube (10), and the rotating mechanism (2) includes a rotating plate (201), the outer wall of the rotating plate (201) is rotatably connected to the middle of the inner wall of the liquid storage tube (10), a baffle 1 (202) is fixedly connected to the middle upper part of the outer wall of the liquid storage tube (10), a baffle 2 (203) is fixedly connected to the middle lower part of the inner wall of the liquid storage tube (10), a rotating rod (204) is fixedly connected to the middle of the inner wall of the rotating plate (201), a valve (205) is fixedly connected to the front side of the rotating rod (204), and a bolt (206) is threadedly connected to the middle of the front side of the valve (205).

3. The eight-channel precision pressure perfusion device according to claim 1, characterized in that: A control panel (12) is fixedly connected to the right side of the front top of the loading box (1), and a plurality of buttons (13) are fixedly connected to the front side of the control panel (12).

4. The eight-channel precision pressure perfusion device according to claim 1, characterized in that: A display screen (14) is fixedly connected to the left side of the front top of the loading box (1), and the display screen (14) is electrically connected to the operating console (12).

5. The eight-channel precision pressure perfusion device according to claim 1, characterized in that: The tops of the left and right ends of the front side of the loading box (1) are both fixedly connected with snap fasteners (15), and the left and right sides of the front side of the cover plate (3) are fixedly connected with pipe clamps (16).

6. The eight-channel precision pressure perfusion device according to claim 1, characterized in that: A handle (17) is fixedly connected to the front side of the top wall of the cover plate (3), and ventilation holes (18) are provided on both the left and right sides of the loading box (1).

7. The eight-channel precision pressure perfusion device according to claim 1, characterized in that: The four corners of the bottom wall of the loading box (1) are all fixedly connected with support columns (19), and the bottom walls of the plurality of support columns (19) are all fixedly connected with anti-slip sleeves (20).

8. The eight-channel precision pressure perfusion device according to claim 1, characterized in that: The left and right sides of the rear top wall of the loading box (1) are fixedly connected with hinges (21), and the front upper end of the hinge (21) is fixedly connected to the rear side of the cover plate (3).

Images