Immune cell thawing instrument
By designing an immune cell thawing instrument with a constant temperature box and a partition frame structure, the contamination problem caused by water bath heating is solved, an efficient and stable cell thawing process is achieved, cross contamination is reduced, and the thawing efficiency of cell bags is improved.
Patent Information
- Application Number
- CN202422686171.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-05
- Publication Date
- 2025-10-10
- Estimated Expiration
- 2034-11-05
AI Technical Summary
In the prior art, thawing immune cells by heating in a water bath is prone to contamination and has low thawing efficiency.
An immune cell thawing instrument was designed, which uses a constant temperature box and a partition frame structure. The sealed space is heated by a water bath for thawing. The combination of the partition frame and the storage frame ensures that the immune cell bags do not directly contact the water source. A heater and a thermostat are used to control the temperature stability. A U-shaped storage frame and partitions are used to separate the cell bags to reduce cross contamination.
The possibility of reducing immune cell contamination during water bath heating is achieved, improving thawing efficiency, being able to thaw more cell bags simultaneously, and maintaining temperature stability.
Smart Images

Figure CN223422686U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field related to immune cell thawing, in particular to an immune cell thawing instrument. Background Art
[0002] Immune cells are an important component of the body's immune system. They are responsible for identifying and clearing antigenic foreign substances from the body, maintaining the body's physiological balance. To maintain the activity and function of immune cells, they are typically frozen and stored, and thawed when needed. Currently, immune cells are primarily thawed using the water bath method. This involves removing the frozen immune cells from a cryogenic environment and quickly placing them in a constant temperature water bath at 37°C to 42°C for rapid thawing. However, this thawing method, combined with direct hydrolysis, can easily lead to immune cell contamination.
[0003] Chinese patent authorization publication number: CN218932160U, authorization publication date: April 28, 2023, discloses a water bath cell thawing device, comprising: a frame; a float, the float being detachably mounted on the frame and having a placement hole provided on the float; and an oscillating device provided on the frame, the oscillating device being capable of generating mechanical oscillations to drive parallel oscillation of the cells to be thawed within the placement hole. A disadvantage of this utility model is that thawing by heating in a water bath can easily cause contamination of immune cells. Utility Model Content
[0004] The utility model aims to overcome the shortcoming of the prior art that the cell is easily contaminated by water source during water bath heating, and provides an immune cell thawing instrument which thaws the cell by heating a sealed space in a water bath.
[0005] In order to achieve the above purpose, the utility model adopts the following technical solutions:
[0006] An immune cell thawing instrument includes a constant temperature box and a storage frame. The constant temperature box is provided with a constant temperature cavity, and the constant temperature box is provided with a partition frame. The two ends of the partition frame are respectively connected to the two side surfaces of the constant temperature cavity on both sides. The partition frame is open at one end of the constant temperature box, and the storage frame is placed in the partition frame and is slidably connected to the partition frame.
[0007] The constant temperature chamber of the thermostat is used to add water. A partition frame is installed in the constant temperature chamber. Both ends of the partition frame are connected to the inner wall of the constant temperature chamber. After the connection, the two ends of the partition frame are closed. An opening is opened at one end of the thermostat, and the opening is connected to the partition frame. The partition frame is a square tube. A storage frame is placed in the partition frame. The immune cells to be thawed are placed in the storage frame. The water source in the thermostat ensures the thawing temperature. The water in the thermostat transfers heat to the partition frame to ensure that the air in the partition frame is at the same temperature as the water source in the thermostat. The heat transfer through water can ensure that the heat increase is more stable and the heating process is more uniform. More immune cell bags can be placed in the storage frame. The immune cell bags are not directly dissolved in water and do not contact each other, reducing the possibility of contamination, thereby achieving the purpose of thawing by heating the sealed space in a water bath.
[0008] Preferably, a top cover is provided on the top of the thermostat, and the top cover is detachably connected to the thermostat. A heater is installed in the thermostat chamber, a thermostat is installed in the thermostat chamber, and a wristband is installed on the top cover. The heater installed in the thermostat heats the water source to increase the water temperature. At the same time, a thermostat is installed in the thermostat chamber to control the water temperature and ensure the stability of the water temperature, so that the water temperature is kept at a constant temperature and can be heated better. At the same time, a top cover is installed on the top surface of the thermostat to reduce heat dissipation and better ensure the stability of the water temperature. A wristband is installed on the top cover for removing the top cover. This design facilitates reducing heat dissipation.
[0009] Preferably, the cross-section of the storage frame is U-shaped, and an inner plate corresponding to the partition frame is installed at one end of the storage frame away from the opening of the partition frame, and a baffle is installed at the other end of the storage frame, and a pull ring is installed on the baffle. Sliding blocks are installed on the upper and lower sides of the storage frame, and a sliding groove is provided on the partition frame. The storage frame is slidably connected to the partition frame through the cooperation of the sliding block and the sliding groove. The storage frame is placed in the partition frame and can be pushed and pulled from the open end of the partition frame. The partition frame is slidably connected to the partition frame through the cooperation of the sliding groove and the sliding block. The pull ring is pulled out to pull out the storage frame to place the immune cell bag. A baffle is installed at one end of the storage frame to close the open end of the partition frame, reducing heat loss in the partition frame to ensure that the immune cell bag in the partition frame is fully thawed. The U-shaped storage frame places the immune cell bag from the open end. After the placement is completed, the storage frame is pushed into the partition frame, and then the immune cell bag is thawed. The immune cell bag only receives air heat in the storage frame, and its position is relatively fixed. At the same time, it does not contact other immune cell bags. Therefore, more immune cell bags can be placed for thawing. This design can thaw more immune cell bags at the same time.
[0010] As preferred, a plurality of partitions are installed in the storage frame, and a hook is installed between two adjacent partitions.
[0011] As preferred, a rotating rod is arranged on the end face of the thermostat, one end of the rotating rod is rotatably connected with the thermostat, a clamping plate is installed on the thermostat, the clamping plate has an L-shaped cross section, the other end of the rotating rod is attached to the inner side face of the clamping plate, a hand lever is installed on the end of the rotating rod attached to the clamping plate, and the inner side face of the rotating rod is attached to the baffle. The rotating rod is rotated after the placing frame is pushed to the position, the inner side face of the rotating rod is attached to the baffle after the rotating rod is rotated, the placing frame is fixed in the partition frame by extruding the baffle, the other end of the rotating rod is attached to the inner side face of the clamping plate, and the one end of the rotating rod is fixed, the fixed rotating rod can better extrude the placing frame, the hand lever is installed on the rotating rod, and the hand lever facilitates the rotation of the rotating rod, and the placing frame can be fixed.
[0012] As preferred, a water changing hole is arranged on the thermostat, the water changing hole is communicated with the thermostat cavity, a plug is arranged in the water changing hole, and the plug corresponds to the water changing hole. The water changing hole is arranged at the lower end of the thermostat, the water changing hole is communicated with the thermostat cavity, the water changing hole is closed by the plug, and when the water in the thermostat cavity needs to be replaced, the plug is pulled out to release the water, and the water source can be replaced conveniently.
[0013] The present application has the advantages that the thawing is performed by water bath heating and sealing the space, heat dissipation is reduced, more immune cell bags can be thawed at the same time, the immune cell bags can be separated, the placing frame can be fixed, and the water source can be replaced conveniently. BRIEF DESCRIPTION OF DRAWINGS
[0014] Figure 1 is a structural schematic view of the present application;
[0015] Figure 2 is Figure 1 is a sectional view of the present application;
[0016] Figure 3 is Figure 1 is a structural schematic view of the thermostat in the present application;
[0017] Figure 4 is Figure 1 is a structural schematic view of the placing frame in the present application.
[0018] In the figure: 1. Constant temperature box; 2. Storage frame; 3. Constant temperature chamber; 4. Partition frame; 5. Top cover; 6. Heater; 7. Thermostat; 8. Wristband; 9. Inner plate; 10. Baffle; 11. Pull ring; 12. Sliding block; 13. Sliding groove; 14. Partition; 15. Hook; 16. Rotating rod; 17. Card plate; 18. Hand lever; 19. Water exchange hole; 20. Block. DETAILED DESCRIPTION
[0019] The present invention will be further described below with reference to the accompanying drawings and specific embodiments.
[0020] like Figure 1 、 Figure 2 In the embodiment shown, an immune cell thawing instrument includes a constant temperature box 1 and a storage frame 2. A constant temperature chamber 3 is provided in the constant temperature box 1. A partition frame 4 is provided in the constant temperature box 1. The two ends of the partition frame 4 are respectively connected to the two side surfaces of the constant temperature chamber 3 on both sides. The partition frame 4 is open at one end of the constant temperature box 1. The storage frame 2 is placed in the partition frame 4 and is slidably connected to the partition frame 4.
[0021] like Figure 3 As shown, a top cover 5 is provided at the top of the thermostat 1, and the top cover 5 is detachably connected to the thermostat 1, a heater 6 is installed in the thermostat cavity 3, a temperature controller 7 is installed in the thermostat cavity 3, and a wristband 8 is installed on the top cover 5.
[0022] like Figure 4 As shown, the cross-section of the storage frame 2 is U-shaped, and an inner plate 9 corresponding to the partition frame 4 is installed at one end of the storage frame 2 away from the opening of the partition frame 4, and a baffle 10 is installed at the other end of the storage frame 2. A pull ring 11 is installed on the baffle 10, and sliding blocks 12 are installed on the upper and lower sides of the storage frame 2. A sliding groove 13 is provided on the partition frame 4. The storage frame 2 is slidably connected to the partition frame 4 through the cooperation of the sliding block 12 and the sliding groove 13.
[0023] A plurality of partitions 14 are installed in the storage frame 2 , and a hook 15 is installed between two adjacent partitions 14 .
[0024] A rotating rod 16 is provided on the end face of the constant temperature box 1, one end of the rotating rod 16 is rotatably connected to the constant temperature box 1, and a card plate 17 is installed on the constant temperature box 1. The cross-sectional shape of the card plate 17 is L-shaped, and the other end of the rotating rod 16 is in contact with the inner side surface of the card plate 17. A hand lever 18 is installed on the end of the rotating rod 16 in contact with the card plate 17, and the inner side surface of the rotating rod 16 is in contact with the baffle 10.
[0025] The thermostat box 1 is provided with a water exchange hole 19 , which is communicated with the thermostat chamber 3 . A blocking block 20 is provided in the water exchange hole 19 , which corresponds to the water exchange hole 19 .
[0026] During use, add water to the constant temperature chamber 3. After adding the constant temperature water, install the top cover 5 to ensure the constant temperature box 1 is airtight. After installing the top cover 5, the heater 6 and thermostat 7 inside the constant temperature chamber 3 maintain the water at a constant temperature conducive to thawing. After the temperature inside the partition frame 4 reaches the same temperature as the water inside the constant temperature chamber 3, pull out the storage frame 2 and hang the thawing bag on the hooks 15 of the storage frame 2. After hanging, push the storage frame 2 into the partition frame 4 to thaw. During thawing, rotate the rotating rod 16 to align it with the baffle 10, securing the storage frame 2 within the partition frame 4.
Claims
1. An immune cell thawing instrument, characterized in that: The invention comprises a constant temperature box (1) and a storage frame (2), wherein the constant temperature box (1) is provided with a constant temperature cavity (3), and the constant temperature box (1) is provided with a partition frame (4), the two ends of the partition frame (4) are respectively connected to the two side surfaces of the constant temperature cavity (3) on both sides, the partition frame (4) is open at one end of the constant temperature box (1), and the storage frame (2) is placed in the partition frame (4) and is slidably connected to the partition frame (4).
2. The immune cell thawing instrument according to claim 1, characterized in that: The top of the thermostat (1) is provided with a top cover (5), and the top cover (5) is detachably connected to the thermostat (1). A heater (6) is installed in the thermostat cavity (3), a temperature controller (7) is installed in the thermostat cavity (3), and a wristband (8) is installed on the top cover (5).
3. The immune cell thawing instrument according to claim 1, characterized in that: The cross-section of the storage frame (2) is U-shaped. An inner plate (9) corresponding to the partition frame (4) is installed at one end of the storage frame (2) away from the opening of the partition frame (4). A baffle (10) is installed at the other end of the storage frame (2). A pull ring (11) is installed on the baffle (10). Sliding blocks (12) are installed on both upper and lower sides of the storage frame (2). A sliding groove (13) is provided on the partition frame (4). The storage frame (2) is slidably connected to the partition frame (4) through the cooperation of the sliding block (12) and the sliding groove (13).
4. The immune cell thawing apparatus according to claim 3, characterized in that: A plurality of partitions (14) are installed in the storage frame (2), and a hook (15) is installed between two adjacent partitions (14).
5. The immune cell thawing apparatus according to claim 4, characterized in that: A rotating rod (16) is provided on the end surface of the thermostatic box (1), one end of the rotating rod (16) is rotatably connected to the thermostatic box (1), a card plate (17) is installed on the thermostatic box (1), the cross-section of the card plate (17) is L-shaped, the other end of the rotating rod (16) is in contact with the inner side surface of the card plate (17), a hand rod (18) is installed on the end of the rotating rod (16) in contact with the card plate (17), and the inner side surface of the rotating rod (16) is in contact with the baffle (10).
6. The immune cell thawing instrument according to claim 1, characterized in that: The thermostatic box (1) is provided with a water exchange hole (19), the water exchange hole (19) is communicated with the thermostatic chamber (3), a blocking block (20) is provided in the water exchange hole (19), and the blocking block (20) corresponds to the water exchange hole (19).
Citation Information
Patent Citations
Cell thawing device of water bath kettle
CN218932160U