Protein purification instrument for research experiment

Abstract

The utility model belongs to the technical field of protein purification instruments, and particularly relates to a protein purification instrument for research experiments, which comprises a protein purification instrument body, a connecting pipe is arranged on the protein purification instrument body, an electronic display screen is arranged at the front end of the protein purification instrument body, and a knob is further arranged at the front end of the protein purification instrument body. A cabinet door is rotationally hinged to the side edge of the protein purification instrument body through a hinge, supporting legs are fixedly installed at the bottom of the protein purification instrument body, and spring columns are fixedly installed at the bottoms of the supporting legs. According to the utility model, parameter setting and real-time monitoring are facilitated through the electronic display screen and the knob, the safety is guaranteed through the design of the cabinet door lock catch, the operation efficiency and convenience are improved, the misoperation risk is reduced, and the experiment process is smoother; the spring columns and the foot pads achieve shock absorption and skid resistance, the cooling fan, the cooling fins and the cooling pipe cooperate to maintain low temperature, internal precision components are protected, stable operation of the protein purification instrument is ensured, and the accuracy and reliability of experimental results are improved.

Description

Technical Field

[0001] The utility model relates to the technical field of protein purification instruments, in particular to a protein purification instrument for research experiments. Background Art

[0002] Protein purification is a key experimental technique in life science research. Pure proteins are crucial for in-depth understanding of protein structure, function, and interactions. A variety of research objectives, such as enzymology, structural biology, and drug discovery, all require highly pure protein samples.

[0003] Traditional protein purification methods often rely on manual labor, such as separation and purification using various chromatography columns. This approach is not only cumbersome, time-consuming, and labor-intensive, but also susceptible to human error, resulting in poor reproducibility of purification results. Furthermore, traditional methods are inefficient when processing large sample volumes, making them difficult to meet the high-throughput protein purification needs of modern life science research.

[0004] In order to overcome the limitations of traditional protein purification methods, researchers urgently need an efficient and automated protein purification instrument. Utility Model Content

[0005] (1) Technical problems solved

[0006] In view of the deficiencies in the prior art, the present invention provides a protein purification instrument for research experiments, which solves the problems raised in the above-mentioned background technology.

[0007] (2) Technical solution

[0008] In order to achieve the above-mentioned purpose, the present invention specifically adopts the following technical solutions:

[0009] A protein purifier for research and experiment includes a protein purifier body, a connecting pipe is provided on the protein purifier body, an electronic display screen is provided at the front end of the protein purifier body, a knob is also provided at the front end of the protein purifier body, a cabinet door is hingedly connected to the side of the protein purifier body by hinges, a support leg is fixedly installed at the bottom of the protein purifier body, a spring column is fixedly installed at the bottom of the support leg, a pad is fixedly connected to the bottom of the spring column, a heat dissipation fan is embedded in the back of the protein purifier body, the heat dissipation fan is close to the heat sink, a cooling pipe is inserted into the interior of the heat sink, and sealing covers are threadedly connected to both ends of the cooling pipe.

[0010] Furthermore, the cabinet door is locked to the protein purifier body via a lock.

[0011] Furthermore, there are a plurality of spring columns which are connected to the fixed legs and the pads in an L-shaped array.

[0012] Furthermore, the heat sink is fixedly mounted on the back of the protein purifier body.

[0013] Furthermore, the cooling pipe is U-shaped and inserted into the heat sink, and the cooling pipe is loaded with coolant.

[0014] Furthermore, a temperature sensor is provided inside the protein purifier body to monitor the internal temperature in real time and display the temperature value on an electronic display screen.

[0015] (3) Beneficial effects

[0016] Compared with the prior art, the present invention provides a protein purification instrument for research experiments, which has the following beneficial effects:

[0017] This utility model facilitates parameter setting and real-time monitoring through the electronic display and knob, and the cabinet door lock design ensures safety, improves operating efficiency and convenience, reduces the risk of misoperation, and makes the experimental process smoother;

[0018] The spring columns and foot pads provide shock absorption and anti-slip properties. The cooling fan, heat sink, and cooling pipe work together to maintain low temperatures, protect the internal precision components, ensure the stable operation of the protein purifier, and improve the accuracy and reliability of experimental results. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 This is a schematic diagram of the three-dimensional structure of the utility model;

[0020] Figure 2 For this utility model Figure 1 Schematic diagram of the structure at A in the middle;

[0021] Figure 3 This is a schematic diagram of the installation structure of the heat dissipation fan of the utility model;

[0022] Figure 4 This is a schematic diagram of the installation structure of the heat sink and cooling pipe of the utility model.

[0023] In the figure: 1. Protein purifier body; 2. Connecting tube; 3. Electronic display screen; 4. Knob; 5. Cabinet door; 6. Lock; 7. Support leg; 8. Spring column; 9. Foot pad; 10. Cooling fan; 11. Heat sink; 12. Cooling tube; 13. Sealing cover. DETAILED DESCRIPTION

[0024] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0025] Example

[0026] like Figure 1-4 As shown, an embodiment of the present invention provides a protein purification instrument for research and experiment, comprising a protein purification instrument body 1;

[0027] The protein purifier body 1 is a box-like structure as a whole, providing a base for the installation of other components, and accommodating working components, circuits, etc. related to protein purification.

[0028] Function: Serves as the core support structure, protecting internal components and ensuring that the protein purification process is carried out in a relatively stable environment, while providing space for the coordinated work of various components.

[0029] The connecting tube 2 is installed on the protein purifier body 1 and is connected to the internal purification system. The material of the connecting tube 2 has certain flexibility and chemical stability.

[0030] Function: Used to transport liquid samples, buffer solutions, eluents, etc. It connects different components and transfers substances during the protein purification process, ensuring smooth flow of fluids between components and achieving protein separation and purification operations.

[0031] The electronic display screen 3 is located at the front end of the protein purifier body 1 and has a visual screen interface that can display various information, such as operation menus, operating parameters, temperature values, purification process status, etc.

[0032] Function: Provides an intuitive human-computer interaction interface for operators, allowing them to understand the working status of the protein purifier, set purification parameters, view purification results, etc. in real time, making operations more convenient and accurate, and improving work efficiency.

[0033] The knob 4 is mounted on the front end of the protein purifier body 1 and is usually round or cylindrical.

[0034] Function: Used to manually adjust certain key parameters of the protein purifier, such as flow rate, pressure, etc., or to select and switch functions during the operation of the device. Used in conjunction with the electronic display 3, it enhances the operator's control over the device.

[0035] The cabinet door 5 is hinged to the side of the protein purifier body 1 through a hinge, which can realize opening and closing movements and has good sealing between the cabinet door 5 and the protein purifier body 1. The cabinet door 5 is of moderate size, which is convenient for opening and closing operations, and in some embodiments, a transparent observation window is provided.

[0036] Function: When closed, it protects the components inside the protein purifier body 1 from external interference, and prevents dust, debris, etc. from entering the interior and affecting the normal operation of the equipment; when opened, it is convenient for operators to perform internal maintenance, inspection, replacement of consumables, etc., and the transparent observation window can observe the internal situation without opening the cabinet door 5, reducing the impact of frequent door opening on the purification process during equipment operation.

[0037] The lock 6 is installed on the cabinet door 5 and the protein purifier body 1, and realizes the locking and unlocking functions between the cabinet door 5 and the protein purifier body 1 through a mechanical structure, which has certain reliability and stability.

[0038] Function: Ensure that the cabinet door 5 is firmly locked in the closed state to prevent the cabinet door 5 from opening accidentally during the operation of the equipment, thereby ensuring the safe operation of the equipment. At the same time, it can also prevent unauthorized personnel from opening the cabinet door 5 at will, thereby protecting the precision components and experimental samples inside the equipment.

[0039] The legs 7 are fixedly mounted on the bottom of the protein purifier body 1 and are generally columnar in structure with a certain height. The material thereof has sufficient strength and stability to support the weight of the entire protein purifier.

[0040] Function: Elevate the protein purifier body 1 and keep it at a certain distance from the placement plane to prevent the moisture and dust on the ground from affecting the equipment. It also facilitates air circulation under the equipment, is beneficial to heat dissipation, and provides stable support for the equipment to prevent the equipment from shaking or tilting during operation.

[0041] The spring columns 8 are in an L-shaped array connecting the fixed legs 7 and the pads 9. The spring columns 8 contain spring components with a certain elastic expansion and contraction capability. The elastic coefficient of the spring columns 8 is designed and selected to adapt to the weight of the equipment and the working environment requirements.

[0042] Function: It plays a role in buffering and shock absorption. When the protein purifier is subjected to external vibration or impact, the spring column 8 can absorb and disperse energy, reduce the impact of vibration on the precision components inside the equipment, and protect the equipment from damage. At the same time, it can also compensate for the equipment tilt problem caused by uneven ground to a certain extent, ensuring that the equipment always maintains a relatively stable horizontal state, which is conducive to the accurate implementation of the protein purification process.

[0043] The foot 9 is fixedly connected to the bottom of the spring column 8 and is made of anti-skid material, such as rubber. Its shape and size are reasonably designed and have a large contact area with the ground.

[0044] Function: Increase the friction between the protein purifier and the placement surface to prevent the device from sliding due to external force or self-vibration during use, further improve the stability of the device, and protect the placement surface from direct pressure and wear due to the weight of the device.

[0045] The heat dissipation fan 10 is embedded in the back of the protein purifier body 1 and fits tightly with the heat sink 11. The fan's blades, motor and other components are optimized to generate sufficient wind power and have good heat dissipation performance and operational stability.

[0046] Function: The rotating blades generate airflow, accelerate the flow of air around the heat sink 11, and take away the heat on the heat sink 11, thereby reducing the temperature inside the protein purifier, ensuring that the equipment will not be affected by overheating during long-term operation and affecting performance or damaging internal components, thereby ensuring the stability and reliability of the protein purification process.

[0047] The heat sink 11 is fixedly mounted on the back of the protein purifier body 1 and is usually made of a metal material with good thermal conductivity, such as aluminum alloy. Its surface is designed with a structure to increase the heat dissipation area, such as fins or corrugations. The heat sink 11 has a channel inside for the cooling tube 12 to be plugged in.

[0048] Function: As a medium for heat transfer, it conducts the heat generated by the internal components of the protein purifier to the surface, and the airflow generated by the heat dissipation fan 10 takes away the heat. At the same time, it cooperates with the cooling pipe 12 to further enhance the heat dissipation effect, effectively reduce the internal temperature of the equipment, maintain the normal operating temperature range of the equipment, and improve the service life and stability of the equipment.

[0049] The cooling tube 12 is U-shaped and inserted into the heat sink 11, and its two ends are connected to the sealing cover 13 by threads. The cooling tube 12 is made of high-temperature resistant and corrosion-resistant materials, such as copper tubes, and is loaded with coolant, which has good heat conduction performance.

[0050] Function: The coolant circulates in the cooling tube 12, absorbs the heat transferred from the heat sink 11, and takes the heat out of the equipment. Together with the heat dissipation fan 10 and the heat sink 11, it forms an efficient heat dissipation system, effectively controlling the internal temperature of the protein purifier, preventing high temperature from causing adverse effects on the protein purification process and equipment, and ensuring stable operation of the equipment.

[0051] The sealing cover 13 is tightly connected to both ends of the cooling pipe 12 through threads. The material of the sealing cover 13 has good sealing and corrosion resistance, ensuring that the coolant will not leak during the operation of the equipment.

[0052] Function: Used to seal both ends of the cooling pipe 12 to prevent coolant leakage, maintain the integrity of the coolant circulation system inside the cooling pipe 12, ensure that the coolant can circulate normally in the cooling pipe 12, thereby ensuring the normal operation of the heat dissipation system and achieving effective heat dissipation function.

[0053] The protein purifier operates based on the principles of multiple chromatography techniques, primarily through the coordinated operation of precision components within the instrument body 1. First, a mixed sample containing the target protein enters the purification system within the instrument body 1 through connecting tube 2. During the purification process, the operator uses the electronic display 3 to observe and set various parameters, such as flow rate and pressure, to optimize purification conditions using knob 4. The purification system performs separation operations based on the characteristics of the target protein using techniques such as ion exchange chromatography, affinity chromatography, and gel filtration chromatography.

[0054] During operation, components within the device generate heat. Heat sink 11 transfers this heat to the surface, and cooling fan 10 accelerates air flow around heat sink 11 to remove the heat. Simultaneously, coolant circulates in cooling tube 12, absorbing heat from heat sink 11 and further enhancing the heat dissipation effect, ensuring a stable temperature within the device. Cabinet door 5, when closed with latch 6, protects internal components and can be opened for maintenance. Legs 7 support the device and, through spring columns 8 and feet 9, provide cushioning and stability, preventing external factors from interfering with the purification process and equipment, thereby achieving efficient and stable protein purification.

[0055] like Figure 1 As shown, in some embodiments, the cabinet door 5 is locked to the protein purifier body 1 via a lock 6. Locking the cabinet door 5 prevents unauthorized or uninformed personnel from arbitrarily opening the cabinet door 5 during device operation, thereby preventing misoperation that could interrupt the protein purification process, damage the device, or affect the accuracy of experimental data. Only trained personnel who understand the device's operating procedures can correctly unlock the cabinet door 5 and enter the device to perform maintenance, inspection, or replacement of consumables, thereby ensuring safe use of the device and the smooth progress of experiments.

[0056] like Figure 2 As shown, in some embodiments, a plurality of spring columns 8 are provided in an L-shaped array, connecting the fixed legs 7 and the feet 9. The L-shaped design of the spring columns 8 enables them to cleverly connect the vertical legs 7 and the horizontal feet 9. The corners are generally rounded to avoid stress concentration and improve the overall strength and durability of the structure.

[0057] like Figure 3As shown, in some embodiments, the heat sink 11 is fixedly mounted on the back of the protein purifier body 1. The heat sink 11 is typically made of a metal material with excellent thermal conductivity, such as aluminum alloy. Aluminum alloy not only has high thermal conductivity, enabling rapid heat transfer from the heat source to the surface of the heat sink 11, but is also lightweight and corrosion-resistant, making it suitable for use in laboratory environments and helping to extend the service life of the heat sink 11.

[0058] like Figure 4 As shown, in some embodiments, the cooling tube 12 is inserted into the heat sink 11 in a U-shaped surround, and the cooling tube 12 is loaded with coolant; the cooling tube 12 is designed as a U-shaped surround structure. This shape can increase the contact area and contact time between the coolant and the heat sink 11 within a limited space. The U-shaped curved portion allows the coolant to fully exchange heat with the heat sink 11 when flowing in the tube, thereby improving the heat dissipation efficiency. At the same time, the U-shaped surround layout also makes the distribution of the cooling tube 12 in the heat sink 11 more uniform, which is conducive to the uniform conduction and dissipation of heat on the entire heat sink 11.

[0059] like Figure 1 As shown, in some embodiments, a temperature sensor is provided within the protein purifier body 1 to monitor the internal temperature in real time and display the temperature value on an electronic display 3. This real-time temperature display is of great significance for the operation of the protein purifier and experimental procedures. By observing the temperature on the electronic display 3, the operator can understand the internal temperature of the device in real time and determine whether the device is within the normal operating temperature range.

[0060] Finally, it should be noted that the above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art will be able to modify the technical solutions described in the aforementioned embodiments or replace some of the technical features therein with equivalents. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention shall be included within the scope of protection of the present invention.

Claims

1. A protein purification instrument for research and experiment, comprising a protein purification instrument body (1), characterized in that: The protein purifier body (1) is provided with a connecting pipe (2), the front end of the protein purifier body (1) is provided with an electronic display screen (3), the front end of the protein purifier body (1) is also provided with a knob (4), the side of the protein purifier body (1) is hingedly connected to a cabinet door (5) by a hinge, the bottom of the protein purifier body (1) is fixedly installed with a support leg (7), the bottom of the support leg (7) is fixedly installed with a spring column (8), the bottom of the spring column (8) is fixedly connected with a pad (9), and a heat dissipation fan (10) is embedded in the back of the protein purifier body (1), the heat dissipation fan (10) is close to the heat sink (11), the interior of the heat sink (11) is plugged with a cooling pipe (12), and the two ends of the cooling pipe (12) are threadedly connected with a sealing cover (13).

2. A protein purification instrument for research experiments according to claim 1, characterized in that: The cabinet door (5) is locked with the protein purifier body (1) via a lock (6).

3. The protein purification apparatus for research experiments according to claim 1, characterized in that: The spring columns (8) are provided in a plurality and are connected to the fixed legs (7) and the pads (9) in an L-shaped array.

4. The protein purification apparatus for research experiments according to claim 1, characterized in that: The heat sink (11) is fixedly mounted on the back of the protein purifier body (1).

5. The protein purification instrument for research experiments according to claim 1, characterized in that: The cooling pipe (12) is U-shaped and inserted into the heat sink (11), and the cooling pipe (12) is loaded with cooling liquid.

6. The protein purification instrument for research experiments according to claim 1, characterized in that: The protein purifier body (1) is provided with a temperature sensor to monitor the internal temperature in real time and display the temperature value on an electronic display screen (3).

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