Compressed air sterilizing and filtering system applied to L-homoserine production
By using a multi-stage filtration system and a buffer tank design, the problem of fermentation interference caused by unsterilized microorganisms in the air is solved, achieving efficient air filtration and cost control, and extending the filter life.
Patent Information
- Application Number
- CN202422819454.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-19
- Publication Date
- 2025-10-17
- Estimated Expiration
- 2034-11-19
AI Technical Summary
In the prior art, microorganisms in the air come into direct contact with the culture without being sterilized, resulting in interference or failure of the fermentation process, poor filtration effects and high production costs.
A compressed air sterilization and filtration system including a sterile tank, a process air storage tank, a sterile filter, a fine filter, a process air total pre-filter and a steam tank was designed. Impurities and moisture were reduced through multi-stage filtration and a buffer tank, thereby improving air quality.
It enhances filtration efficiency, reduces the chance of bacterial contamination and control costs, extends filter life, and improves air quality.
Smart Images
Figure CN223439451U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to the field of microbial fermentation technology, concretely is applied to a compressed air sterilization filter system for L-homoserine production. BACKGROUND
[0002] In the fermentation process, the microorganisms in the air are an important consideration factor. The air contains a variety of microorganisms, including bacteria, fungal spores, etc. If these microorganisms are not subjected to sterilization treatment and directly contact with the culture, they will rapidly multiply under suitable conditions, consume a large amount of nutrients and produce various metabolites. This not only interferes with and even destroys the intended fermentation process, leading to a decrease in fermentation yield, and may even completely fail.
[0003] The methods of air sterilization mainly include physical methods and chemical methods. Physical methods such as heat sterilization, radiation sterilization (including ultraviolet, X-ray, etc.), electrostatic sterilization and medium filtration sterilization, etc. These methods kill or remove microorganisms in the air through different principles to ensure that the air entering the fermentation system is sterile. Chemical methods mainly kill microorganisms by using disinfectants, but this method is usually not suitable for the fermentation industry because it may contaminate the fermentation product. Heat sterilization heats the air to a certain temperature by heating means to kill heat-resistant microorganisms such as bacterial spores. Radiation sterilization uses rays or electromagnetic waves to damage the DNA structure of microorganisms, thereby achieving sterilization effect. Electrostatic sterilization utilizes electric field to charge microorganisms in the air, and then removes them through the action of electric field. Medium filtration sterilization captures microorganisms and particles in the air through filter medium, thereby achieving the purpose of purifying air.
[0004] The preparation of sterile air becomes an important link in fermentation engineering. In the prior art, for closed deep aerobic fermentation, strict sterility is required, and sterilization measures must be taken. Since the air contains moisture and oil mist impurities, it must also be cooled, dehydrated and deoiled, etc. Therefore, the preparation of sterile air must go through a complex air treatment process. After the air is compressed by the air compressor, the air compressor itself does not remove the impurities and bacteria in the air, and also brings some oil and water into the compressed air. By taking special treatment methods to remove the oil and water in the air first, and then removing the remaining impurities and bacteria in the air through special filter devices, the quality of the air is ensured to meet the requirements of the workshop for sterile air.
[0005] In the fermentation industry, most of them are pure culture using aerobic microorganisms, and air is essential for microbial growth and metabolism. But the air contains a variety of microorganisms, these microorganisms with air into the culture medium, under suitable conditions, they will rapidly multiply, consume a large amount of nutrients and produce a variety of metabolites; interfere with and even destroy the normal progress of the predetermined fermentation, make the fermentation yield decline, even completely failed.
[0006] Therefore, the compressed air sterilization filter system applied to L-homoserine production is urgently needed to solve the problems of poor filtering effect and high production cost. The utility model discloses a compressed air sterilization filter system applied to L-homoserine production.
[0007] In view of the above fact, the compressed air sterilization filter system applied to L-homoserine production is designed to solve the problems of poor filtering effect and high production cost.
[0008] To achieve the above object, the utility model adopts the following technical scheme:
[0009] The compressed air sterilization filter system applied to L-homoserine production includes a sterile tank, a process air storage tank, a sterile filter, a fine filter, a first process air total prefilter, a first process air total filter, a steam tank, a second process air total prefilter and a second process air total filter.
[0010] The first pipeline is connected with the sterile tank on the left side and the process air storage tank on the right side, and is sequentially installed with a tank air inlet regulating valve, a sterile filter, a filter communication valve, a fine filter, a first filter air inlet valve, a second filter air inlet valve, a first prefilter outlet valve, a first process air total prefilter, a first process air communication valve, a first process air total filter and a first process air total valve.
[0011] The fourth pipeline is connected with the steam tank on the left side and the first pipeline on the right side, and is sequentially installed with a filter steam inlet near tank valve and a filter steam inlet far tank valve.
[0012] The sixth pipeline is connected with the first pipeline on the left side, and is sequentially installed with a second prefilter outlet valve, a second process air total prefilter, a second process air communication valve, a second process air total filter and a second process air total valve.
[0013] The ninth pipeline is connected with the process air storage tank on the left side and the air compressor outlet tank on the right side.
[0014] Further, the tank air inlet regulating valve is connected with an air inlet tank small exhaust on the left side below, and connected with an exhaust valve of the filter on the right side below.
[0015] Further, the sterile filter is connected with a filter exhaust valve below, the fine filter is connected with a fine filter exhaust valve below, the first process air total prefilter is connected with a first prefilter exhaust valve below, the first process air total filter is connected with a first total filter exhaust valve below, and the process air storage tank is connected with an air storage tank exhaust valve below.
[0016] The second process air total prefilter is connected with a second prefilter exhaust valve below, and the second process air total filter is connected with a second total filter exhaust valve below.
[0017] Further, a second pipeline is connected with the first pipeline, and a first anti-dead air small exhaust is arranged on the second pipeline.
[0018] A third pipeline is connected with the first pipeline, and a second anti-dead air small exhaust is arranged on the third pipeline.
[0019] Further, a fifth pipeline is connected with the fourth pipeline, and a steam condensate water small exhaust is arranged on the fifth pipeline.
[0020] Further, a seventh pipeline is connected with the sixth pipeline, and a third anti-dead air small exhaust is arranged on the seventh pipeline.
[0021] An eighth pipeline is connected with the sixth pipeline, and a fourth anti-dead air small exhaust is arranged on the eighth pipeline.
[0022] The beneficial effects of the utility model lie in:
[0023] 1. The utility model discloses an air buffer tank and a prefilter are added after improvement, impurities and moisture content in air are reduced, air system pressure fluctuation is avoided, and filter core service life is prolonged.
[0024] 2. The utility model discloses strengthen the filtration effect, improve air quality.
[0025] 3. The utility model discloses reduce the workshop bacteria contamination probability, reduce bacteria contamination control cost. DRAWINGS
[0026] Figure 1 It is the structure schematic drawing of the utility model;
[0027] In the figure: 1 - aseptic tank, 2 - process air storage tank, 3 - tank inlet air regulating valve, 4 - aseptic filter, 5 - filter communication valve, 6 - fine filter, 7 - first filter inlet air valve, 8 - second filter inlet air valve, 9 - first pre-filter outlet valve, 10 - first process air communication valve, 11 - first process air total filter, 12 - first process air inlet air total valve, 13 - inlet air tank small exhaust, 14 - filter exhaust valve, 15 - fine filter exhaust valve, 16 - pre-filter exhaust valve, 17 - first total filter exhaust valve, 18 - air storage tank exhaust valve, 19 - first dead air prevention small exhaust, 20 - second dead air prevention small exhaust, 21 - steam tank, 22 - filter inlet steam tank valve, 23 - filter inlet steam remote tank valve, 24 - steam condensate water small exhaust, 25 - second pre-filter outlet valve, 26 - second process air total pre-filter, 27 - second process air communication valve, 28 - second process air total filter, 29 - second process air inlet air total valve, 30 - second pre-filter exhaust valve, 31 - second total filter exhaust valve, 32 - third dead air prevention small exhaust, 33 - fourth dead air prevention small exhaust, 34 - air compressor outlet air tank. DETAILED DESCRIPTION
[0028] In order to make the personnel in the technical field better understand the scheme of the present application, the technical scheme in the embodiments of the present application will be clearly and completely described below in combination with the drawings in the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor should belong to the protection scope of the present application.
[0029] It should be noted that the terms "first", "second" and the like in the specification and claims of the present application and the above-described drawings are used to distinguish similar objects, and do not necessarily indicate a specific order or a chronological sequence. It should be understood that the data thus used can be interchanged under appropriate circumstances, so that the embodiments of the present application described herein can be implemented. In addition, the terms "include" and "have" and any variations thereof are intended to cover non-exclusive inclusion, for example, a process, method, system, product or device including a series of steps or units does not necessarily have to include only those steps or units clearly listed, but can include other steps or units not clearly listed or inherent to the process, method, product or device.
[0030] In the present application, the terms "upper", "lower", "inner", "middle", "outer", "front", "back" and the like indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings. These terms are mainly used to better describe the present application and its embodiments, and are not intended to limit the indicated devices, elements or components to have a specific orientation, or to be constructed and operated in a specific orientation.
[0031] In addition, in addition to indicating the orientation or positional relationship, the above-mentioned partial terms can also be used to indicate other meanings, for example, the term "upper" can also be used to indicate a certain dependent relationship or connection relationship in some cases. For those skilled in the art, the specific meaning of these terms in the present application can be understood according to the specific circumstances.
[0032] In addition, the terms "set", "connected", "fixed" should be understood broadly. For example, "connected" can be fixedly connected, detachably connected, or integrally constructed; it can be mechanically connected, or electrically connected; it can be directly connected, or indirectly connected through an intermediate medium, or it can be internal communication between two devices, elements or components. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances.
[0033] It should be noted that the embodiments in the present application and the features in the embodiments can be combined with each other without conflict. The present application will be described in detail below with reference to the drawings and in conjunction with the embodiments.
[0034] The preferred embodiments of the present application will be described in detail below with reference to the drawings.
[0035] Embodiment 1: A compressed air sterilization filtration system applied to L-homoserine production, comprising a sterile tank 1, a process air storage tank 2, a sterile filter 4, a fine filter 6, a first process air total pre-filter 10, a first process air total filter 12, a steam tank 23, a second process air total pre-filter 28, and a second process air total filter 30;
[0036] The first pipeline is connected to the sterile tank 1 on the left side and connected to the process air storage tank 2 on the right side. The first pipeline is sequentially installed with a tank air inlet regulating valve 3, a sterile filter 4, a filter communication valve 5, a fine filter 6, a first filter air inlet valve 7, a second filter air inlet valve 8, a first pre-filter outlet valve 9, a first process air total pre-filter 10, a first process air communication valve 11, a first process air total filter 12, and a first process air total valve 13.
[0037] The fourth pipeline is connected to the steam tank 23 on the left side and connected to the first pipeline on the right side. The right connection point is between the sterile filter 4 and the filter communication valve 5. The fourth pipeline is sequentially installed with a filter steam inlet near tank valve 24 and a filter steam inlet far tank valve 25.
[0038] The sixth pipeline connects the first pipeline on the left side, the left connection point is between the second filter air inlet valve 8 and the first pre-filter outlet valve 9, and the right side connects the first process air pipeline on the right side, the right connection point is between the first process air pipeline air inlet master valve 13 and the process air storage tank 2, and the sixth pipeline is sequentially provided with a second pre-filter outlet valve 27, a second process air pipeline total pre-filter 28, a second process air pipeline communication valve 29, a second process air pipeline total filter 30, and a second process air pipeline air inlet master valve 31.
[0039] The ninth pipeline connects the process air storage tank 2 on the left side and connects the air compressor air outlet tank 36 on the right side.
[0040] More specifically, the tank air inlet regulating valve 3 is connected to the air inlet tank small exhaust valve 14 on the left side below, and connected to the filter exhaust valve 15 on the right side below.
[0041] More specifically, the sterile filter 4 is connected to the filter exhaust valve 16 below, the fine filter 6 is connected to the fine filter exhaust valve 17 below, the first process air pipeline total pre-filter 10 is connected to the first pre-filter exhaust valve 18 below, the first process air pipeline total filter 12 is connected to the first total filter exhaust valve 19 below, and the process air storage tank 2 is connected to the air storage tank exhaust valve 20 below.
[0042] The second process air pipeline total pre-filter 28 is connected to the second pre-filter exhaust valve 32 below, and the second process air pipeline total filter 30 is connected to the second total filter exhaust valve 33 below.
[0043] More specifically, the second pipeline connects the first pipeline, the connection point is between the first pre-filter outlet valve 9 and the first process air pipeline total pre-filter 10, and the second pipeline is provided with a first anti-dead air small exhaust valve 21.
[0044] The third pipeline connects the first pipeline, the connection point is between the first process air pipeline communication valve 11 and the first process air pipeline total filter 12, and the third pipeline is provided with a second anti-dead air small exhaust valve 22.
[0045] More specifically, the fifth pipeline connects the fourth pipeline, the connection point is between the filter steam inlet tank valve 24 and the filter steam inlet remote tank valve 25, and the fifth pipeline is provided with a steam exhaust condensate water small exhaust valve 26.
[0046] More specifically, the seventh pipeline connects the sixth pipeline, the connection point is between the second pre-filter outlet valve 27 and the second process air pipeline total pre-filter 28, and the seventh pipeline is provided with a third anti-dead air small exhaust valve 34.
[0047] The eighth pipeline connects the sixth pipeline, the connection point is between the second process air pipeline communication valve 29 and the second process air pipeline total filter 30, and the eighth pipeline is provided with a fourth anti-dead air small exhaust valve 35.
[0048] Embodiment 2: The compressed air sterilization filtration system applied to L-homoserine production in this embodiment has the following operation process:
[0049] Step 1: Air is compressed by an air compressor.
[0050] Step 2: The air entering the air compressor is coarsely filtered.
[0051] Step 3: The compressed air is heated and cooled to remove water and oil.
[0052] Step 4: The compressed air enters the final filter for filtration.
[0053] More specifically, the specific implementation process of Step 2 is to coarsely filter the air entering the air compressor to remove solid particles such as dust and sand, which is also beneficial to the normal operation of the air compressor and improves the service life of the air compressor.
[0054] More specifically, the specific implementation process of Step 3 is that the air enters the dehumidification system to remove most of the water and oil in the compressed air. The air temperature is raised to 55 degrees Celsius using steam, and the residual oil and water are discharged through an air buffer tank. An oil-water separator combined with a demister (dehumidifier) is commonly used.
[0055] More specifically, in order to prevent the increase of instantaneous air consumption from causing air system pressure fluctuations and to maintain stable air system pressure, one or more air storage tanks are required in the process, just like general air supply.
[0056] More specifically, the air filter uses two total filters for cross use, and each fermentation tank is equipped with a separate filter combined with a separate filter.
[0057] More specifically, the sterile compressed air pressure is generally controlled at 0.23-0.26 MPa, the air temperature is controlled at about 55°C, and the air humidity is as low as possible. The role of the air buffer tank is used to ensure relatively stable pressure into the fermentation tank and the sterile tank.
[0058] More specifically, the air first passes through the total air filter to remove large impurities in the air using internal fillers, then enters the total pre-filter to remove the remaining impurities in the air using air filter cartridges, and finally enters the final filter to remove residual impurities and bacteria using high-precision filter cartridges to produce sterile air entering each sterile tank in the workshop.
[0059] Finally, it should be noted that the above examples are only used to illustrate the technical solutions of the present application, and are not limiting; although the present application has been described in detail with reference to the foregoing examples, the technical solutions described in the foregoing examples can still be modified, or some or all of the technical features can be replaced by equivalents; as long as there is no structural conflict, each feature in the specific embodiments disclosed in the present application can be used in combination with any other feature, and will not cause the corresponding technical solution to deviate from the scope of the technical solutions of the present application.
[0060] In addition, it should be understood that, although the present specification is described in terms of embodiments, not every embodiment contains only one independent technical solution, and the description of the specification is only for the sake of clarity, and those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that those skilled in the art can understand.
Claims
1. The compressed air sterilization filtration system used in L-homoserine production is characterized by: It comprises a sterile tank (1), a process air storage tank (2), a sterile filter (4), a fine filter (6), a first process air total pre-filter (10), a first process air total filter (12), a steam tank (23), a second process air total pre-filter (28), and a second process air total filter (30); The first pipeline is connected to the sterile tank (1) on the left side and to the process air storage tank (2) on the right side. The first pipeline is sequentially installed with a tank air inlet regulating valve (3), a sterile filter (4), a filter connecting valve (5), a fine filter (6), a first filter air inlet valve (7), a second filter air inlet valve (8), a first pre-filter outlet valve (9), a first process air total pre-filter (10), a first process air connecting valve (11), a first process air total filter (12), and a first process air inlet main valve (13); The fourth pipeline is connected to the steam tank (23) on the left side and to the first pipeline on the right side. The right connection point is between the sterile filter (4) and the filter connecting valve (5). The fourth pipeline is sequentially installed with the filter steam inlet valve (24) and the filter steam inlet valve (25). The left side of the sixth pipeline is connected to the first pipeline, and the left connection point is between the second filter air inlet valve (8) and the first pre-filter outlet valve (9). The right side is connected to the first pipeline, and the right connection point is between the first process air inlet main valve (13) and the process air storage tank (2). The sixth pipeline is sequentially installed with the second pre-filter outlet valve (27), the second process air main pre-filter (28), the second process air connecting valve (29), the second process air main filter (30), and the second process air inlet main valve (31); The left side of the ninth pipeline is connected to the right side of the process air storage tank (2), and the right side is connected to the air compressor outlet tank (36).
2. The compressed air sterilization and filtration system for L-homoserine production according to claim 1, characterized in that: The left side below the tank air inlet regulating valve (3) is connected to the tank air inlet small row (14), and the right side below is connected to the exhaust valve (15) of the filter.
3. The compressed air sterilization and filtration system for L-homoserine production according to claim 1, characterized in that: The sterile filter (4) is connected to a filter exhaust valve (16) below, the fine filter (6) is connected to a fine filter exhaust valve (17) below, the first process air total pre-filter (10) is connected to a first pre-filter exhaust valve (18) below, the first process air total filter (12) is connected to a first total filter exhaust valve (19) below, and the process air storage tank (2) is connected to an air storage tank exhaust valve (20) below; The second process air total pre-filter (28) is connected to a second pre-filter exhaust valve (32) below, and the second process air total filter (30) is connected to a second total filter exhaust valve (33) below.
4. The compressed air sterilization and filtration system for L-homoserine production according to claim 1, characterized in that: The second pipeline is connected to the first pipeline, and the connection point is between the first pre-filter outlet valve (9) and the first process air total pre-filter (10). The second pipeline is equipped with a first dead air prevention small row (21); The third pipeline is connected to the first pipeline, and the connection point is between the first process air connecting valve (11) and the first process air total filter (12). The third pipeline is equipped with a second dead air prevention small row (22).
5. The compressed air sterilization and filtration system for L-homoserine production according to claim 1, characterized in that: The fifth pipeline is connected to the fourth pipeline, and the connection point is between the filter steam inlet tank valve (24) and the filter steam inlet tank valve (25). The fifth pipeline is equipped with a steam condensate drain (26).
6. The compressed air sterilization and filtration system for L-homoserine production according to claim 1, characterized in that: The seventh pipeline is connected to the sixth pipeline, and the connection point is between the second pre-filter outlet valve (27) and the second process air total pre-filter (28). The third dead air prevention small row (34) is installed on the seventh pipeline; The eighth pipeline is connected to the sixth pipeline, and the connection point is between the second process air connecting valve (29) and the second process air total filter (30). The fourth dead air prevention small row (35) is installed on the eighth pipeline.