Spray drying device for chemical pharmacy

By introducing a grinding barrel and grinding roller into the spray drying device, centrifugal force and high-temperature hot air are used to form drug crystals, and they are refined through grinding, which solves the problem of excessively large drug crystal particles, achieves uniform refinement of drug particles and improves production efficiency.

CN223439769UActive Publication Date: 2025-10-17武汉华夏理工学院
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Patent Information

Application Number
CN202422634976.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-30
Publication Date
2025-10-17
Estimated Expiration
2034-10-30

AI Technical Summary

Technical Problem

During the drying process of existing chemical pharmaceutical spray drying equipment, the crystal particles of the liquid medicine tend to adhere to the inner wall of the box to form crystals, resulting in larger particle size, which is difficult to meet the requirements of subsequent drug production and requires additional grinding.

Method used

A grinding barrel and grinding roller are installed in the spray drying device. Centrifugal force and high-temperature hot air are used to atomize the drug liquid and adhere it to the inner surface of the conical tank to form crystals. The crystal particles are ground into drug particles and powder of fixed size through the extrusion action of the grinding roller and grinding barrel.

Benefits of technology

The uniform refinement of drug particles is achieved, the drug production process is simplified, additional grinding steps are avoided, and production efficiency is improved.

✦ Generated by Eureka AI based on patent content.

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    Figure CN223439769U_ABST
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Abstract

The utility model discloses a spray drying device for chemical pharmacy, and relates to the field of pharmacy, the spray drying device comprises a conical tank, a grinding barrel is welded to the end, located in a conical hole, of the conical tank, a round hole is formed in the joint of the grinding barrel and the conical tank, one end of the grinding barrel is fixedly connected with a supporting plate, and a driving motor is fixedly mounted at the top of the supporting plate; the output end of the driving motor is fixedly connected with a driving shaft, the driving shaft movably penetrates through the grinding barrel, the driving shaft fixedly penetrates through a grinding roller, the grinding roller is movably connected into the grinding barrel in a sleeved mode, and the interval between the diameter of the driving shaft and the inner diameter of the grinding barrel is two millimeters. The grinding barrel and the grinding roller are mounted at one end of the conical tank for drying and atomizing the liquid medicine, medicine particles formed on the inner surface of the conical tank fall off and then are ground into medicine particles and medicine powder within a fixed size under the action of the grinding barrel and the grinding roller, so that subsequent medicine preparation is facilitated, and the production efficiency is improved. And the effect of simplifying the medicine preparation process is achieved.
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Description

TECHNICAL FIELD

[0001] The present application relates to the field of pharmacy, in particular to a chemical pharmacy spray drying device. BACKGROUND

[0002] In the production of pharmaceuticals, it is often necessary to make the reaction liquid into powder or granules for the production of granules, powder for tablets, powder for capsules.

[0003] In addition, the existing Chinese patent CN219272160U discloses a chemical pharmacy spray drying device, which still has the following shortcomings in actual use:

[0004] The above-mentioned patent dries the atomized liquid medicine in the box by an electric heating fan. Since the water mist mixed with the liquid medicine adheres to the inner wall of the box, crystalline medicine particles are slowly formed during the gradual drying process. These particles are sticky to the inner wall of the box. Only when the crystalline particles become larger and larger, and their own weight is greater than the friction force attached to the surface of the box, they will be separated from the inner wall of the box under the action of gravity and fall off. Since the volume of these crystalline particles gradually increases during the drying and forming process, it does not meet the requirements of the subsequent powder for tablets and powder for capsules. Therefore, the crystalline medicine particles need to be ground again to make them into smaller medicine powder. Therefore, the present application provides a chemical pharmacy spray drying device. Content of the utility model

[0005] In order to solve the problem of large particle size of medicine after drying and crystallization, the present application provides a chemical pharmacy spray drying device.

[0006] The chemical pharmacy spray drying device provided by the present application adopts the following technical scheme:

[0007] A chemical pharmacy spray drying device, comprising a conical core tank, a grinding barrel is welded at one end of the conical hole of the conical core tank, a circular hole is formed at the connection between the grinding barrel and the conical core tank, a support plate is fixedly connected to one end of the grinding barrel, a driving motor is fixedly installed at the top of the support plate, a driving shaft is fixedly connected to the output end of the driving motor, the driving shaft is movably penetrated through the grinding barrel, a grinding roller is fixedly penetrated through the driving shaft, and the grinding roller is movably sleeved in the interior of the grinding barrel.

[0008] Preferably, a storage box is welded vertically below the outer peripheral surface of the grinding barrel, a rectangular leakage hole is formed at the connection between the grinding barrel and the storage box, a storage box is slidably connected in the interior of the storage box, and a handle is fixedly installed at the end of the storage box away from the grinding roller.

[0009] Preferably, a cover plate is welded at the top end of the conical core tank, and an exhaust pipe is welded in the middle of the cover plate.

[0010] Preferably, the top side of the cover plate is provided with a rectangular mounting hole, and a water distributor is fixedly installed on the rectangular mounting hole through bolts.

[0011] Preferably, a side plate is fixedly connected to the side of the cover plate close to the water distributor, and a pump machine is fixedly installed on the top of the side plate.

[0012] Preferably, an electric heating fan is fixedly installed on the top of the cover plate, and the output end of the electric heating fan is connected to the injection hole on the side of the cover plate close to the rectangular mounting hole through a pipeline.

[0013] Preferably, the outer circumferential surface of the conical core tank is fixedly connected to two groups of support legs in a symmetrical manner, and the bottom end of the two support legs is fixedly connected to a bottom plate.

[0014] Preferably, the outer circumferential surface of the grinding roller is provided with grinding grooves at equal intervals, and the depth of the grinding grooves is one millimeter.

[0015] In summary, the present application includes at least one of the following beneficial technical effects:

[0016] 1. By installing a grinding barrel and a grinding roller on one end of the conical core tank for drying atomized medicinal liquid, under the action of the grinding barrel and the grinding roller, the drug particles formed on the inner surface of the conical core tank are ground into drug particles and drug powder with a size within a fixed range after falling off, thereby facilitating the subsequent preparation of the drug and achieving the effect of simplifying the drug preparation process.

[0017] 2. By using an electric heating fan, the atomized medicinal liquid entering the conical core tank can rotate in the conical core tank accompanied by high-temperature hot air, and under the action of centrifugal force, the drug particles can gradually form and be adsorbed on the inner surface of the conical core tank, thereby achieving the effect of accelerating the formation of drug particles. BRIEF DESCRIPTION OF DRAWINGS

[0018] Figure 1 It is a schematic diagram of the overall structure of the present application file;

[0019] Figure 2 It is a schematic diagram of the cross-sectional structure of the present application file;

[0020] Figure 3 It is a schematic diagram of the local cross-sectional structure of the present application file;

[0021] Figure 4 It is a schematic diagram of the local structure of the present application file;

[0022] Figure 5 It is a schematic diagram of the local cross-sectional structure of the present application file;

[0023] Figure 6The structure diagram of the grinding roller of the present application file.

[0024] Reference signs: 1, conical core tank; 2, support leg; 201, bottom plate; 3, grinding barrel; 4, support plate; 5, driving motor; 6, driving shaft;

[0025] 7, grinding roller; 701, grinding groove;

[0026] 8, storage box; 9, storage box; 10, handle; 11, cover plate; 1101, exhaust pipe; 1102, rectangular mounting hole; 12, electric heating fan; 13, side plate; 14, pump; 15, valve; 16, water distributor; 17, atomizing nozzle. DETAILED DESCRIPTION

[0027] The following will be described in detail in combination with the accompanying Figures 1-6 The present application is further described in detail.

[0028] The embodiment of the present application discloses a chemical pharmaceutical spray drying device.

[0029] Referring to Figures 1-4 and Figure 6 , a chemical pharmaceutical spray drying device includes a conical core tank 1, the upper half of the conical core tank 1 is cylindrical, the lower half is conical, the conical core tank 1 is welded with a grinding barrel 3 at one end of the conical hole, a circular hole is formed at the connection of the grinding barrel 3 and the conical core tank 1, the diameter of the circular hole is the same as the diameter of one end of the conical core tank 1, a support plate 4 is welded below one end of the grinding barrel 3, the top of the support plate 4 is fixedly connected with the base of the driving motor 5 through bolts, the output end of the driving motor 5 is fixedly connected with a driving shaft 6, the driving shaft 6 movably penetrates through both ends of the grinding barrel 3, the grinding barrel 3 is welded by a hollow pipe and a sealing plate, the grinding roller 7 is fixedly penetrated by the driving shaft 6, the grinding roller 7 movably sleeves in the inside of the grinding barrel 3, the diameter of the grinding roller 7 and the inner diameter of the grinding barrel 3 are spaced by two millimeters, the two-millimeter spacing is set, so that the diameter of the falling crystal can be kept within two millimeters during the grinding process, thereby ensuring the fineness of the particles.

[0030] Referring to Figures 1-4 and Figure 6As shown, the outer peripheral surface of the grinding barrel 3 is welded with a storage box 8 vertically below the support plate 4, and the connection between the grinding barrel 3 and the storage box 8 is provided with a rectangular leakage hole for discharging the raw materials inside the grinding barrel 3, the inside of the storage box 8 is slidably connected with a storage box 9, the storage box 9 is used to collect the falling drug powder, the end of the storage box 9 away from the grinding roller 7 is fixedly installed with a handle 10, the handle 10 is used to pull the storage box 9 to move, so as to achieve the effect of convenient collection, the top of the conical core tank 1 is welded with a cover plate 11, the diameter of the cover plate 11 is the same as the diameter of the upper half of the conical core tank 1, a circular hole is formed in the middle of the cover plate 11, and an exhaust pipe 1101 is welded at the circular hole, one end of the air inlet of the exhaust pipe 1101 extends to the middle position of the lower half of the conical core tank 1, so as to ensure that the discharged gas does not mix with the drug particles.

[0031] Referring to Figure 5 Referring to Figure 1 and Figure 5 As shown, the top side of the cover plate 11 is provided with a rectangular mounting hole 1102, a water separator 16 is fixedly installed on the rectangular mounting hole 1102 through bolts, the water separator 16 is provided with a cavity inside, the bottom of the water separator 16 is fixedly installed with an atomizing nozzle 17 at equal intervals, the atomizing nozzle 17 is completely located inside the cover plate 11, so as to ensure that the atomized liquid medicine does not leak and overflow, the side plate 13 is welded on the side of the cover plate 11 close to the water separator 16, the top of the side plate 13 is fixedly connected with the mounting seat of the pump 14 through bolts, the input end of the pump 14 is threadedly connected with a valve 15, the output end of the pump 14 is threadedly connected with a pipeline, the other end of the pipeline is threadedly connected with the water separator 16, the pump 14 provides sufficient pressure for the atomizing nozzle 17, so as to make the liquid medicine into water mist.

[0032] Referring to Figure 1 , Figure 2 and Figure 5 As shown, the top side of the cover plate 11 is fixedly connected with the bottom of the electric heating fan 12 through bolts, the output end of the electric heating fan 12 is connected with an injection hole on the side of the cover plate 11 close to the rectangular mounting hole 1102 through a pipeline, the injection hole is located on the side of the atomizing nozzle 17, so that the hot air blown out by the electric heating fan 12 can carry the water mist made by the atomizing nozzle into the conical core tank 1, the outer peripheral surface of the conical core tank 1 is symmetrically welded with two groups of support legs 2, the bottom ends of the two support legs 2 are welded with a bottom plate 201, the outer peripheral surface of the grinding roller 7 is provided with grinding grooves 701 at equal intervals, the depth of the grinding grooves 701 is one millimeter, the grinding grooves 701 can provide sufficient friction for the falling crystal drug particles, which can accelerate the breaking speed of the crystal and achieve the effect of preventing clogging.

[0033] The implementation principle of the spray drying device for chemical pharmacy according to the embodiment of the application is as follows: first, the liquid storage tank containing the liquid medicine is connected to the valve 15 through the pipeline, under the action of the pump 14, the liquid medicine in the liquid storage tank is pumped into the cavity in the water distributor 16, under the action of the pump 14, after the pressure reaches a certain condition, the liquid medicine is atomized on the cover plate 11 under the action of the atomizing nozzle 17, at the same time, the electric heating fan 12 is started, so that the hot air carrying the atomized liquid medicine enters the conical core tank 1 on the side of the cover plate 11 close to the atomizing nozzle 17, under the action of the conical core tank 1, the water mist containing the liquid medicine rotates in the conical core tank 1, under the action of the centrifugal force, the liquid medicine is attached to the inner surface of the conical core tank 1, under the action of high temperature, the atomized liquid medicine is evaporated into crystal particles attached to the inner surface of the conical core tank 1, when the crystal gradually becomes larger over time, the mass of the crystal is greater than the frictional force of the inner surface of the conical core tank 1, the crystal particles will fall off and fall into the grinding barrel 3, at this time, the driving motor 5 is started to drive the driving shaft 6 and the grinding roller 7 to rotate, in the process of rotation, the grinding grooves 701 on the surface of the grinding roller 7 will drive the falling crystal particles to enter the gap between the grinding roller 7 and the grinding barrel 3, under the extrusion of the grinding roller 7 and the grinding barrel 3, the crystal medicine can be extruded to form smaller medicine particles and medicine powder, so as to achieve the grinding effect, finally, the medicine particles and medicine powder will fall into the storage box 9 under the action of gravity and be collected, so as to achieve the effect of collecting medicine.

[0034] The above is only an optional embodiment of the present disclosure and is not used to limit the present disclosure. For those skilled in the art, the present disclosure can have various modifications and changes. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present disclosure shall be included in the protection scope of the present disclosure.

Claims

1. A spray drying device for chemical pharmaceuticals, comprising a conical core tank (1), characterized in that: A grinding barrel (3) is welded to one end of the conical hole of the conical core tank (1); a circular hole is provided at the connection between the grinding barrel (3) and the conical core tank (1); a support plate (4) is fixedly connected to one end of the grinding barrel (3); a driving motor (5) is fixedly installed on the top of the supporting plate (4); an output end of the driving motor (5) is fixedly connected to a driving shaft (6); the driving shaft (6) and the grinding barrel (3) are movably penetrated; a grinding roller (7) is fixedly penetrated by the driving shaft (6); and the grinding roller (7) is movably sleeved inside the grinding barrel (3).

2. A chemical pharmaceutical spray drying device according to claim 1, characterized in that: A material storage box (8) is welded to the outer peripheral surface of the grinding barrel (3) vertically below the support plate (4); a rectangular leak hole is provided at the connection between the grinding barrel (3) and the material storage box (8); a material storage box (9) is slidably connected to the interior of the material storage box (8); and a grip rod (10) is fixedly installed at one end of the material storage box (9) away from the grinding roller (7).

3. The spray drying device for chemical pharmaceuticals according to claim 1, characterized in that: A cover plate (11) is welded to the top end of the conical core tank (1), and an exhaust pipe (1101) is welded to the middle of the cover plate (11).

4. A chemical pharmaceutical spray drying device according to claim 3, characterized in that: A rectangular mounting hole (1102) is provided on one side of the top of the cover plate (11), a water distributor (16) is fixedly mounted on the rectangular mounting hole (1102) by means of bolts, and an atomizing nozzle (17) is fixedly mounted at an equal distance on the bottom of the water distributor (16).

5. The spray drying device for chemical pharmaceuticals according to claim 3, characterized in that: A side plate (13) is fixedly connected to a side of the cover plate (11) close to the water distributor (16), a pump (14) is fixedly installed on the top of the side plate (13), an input end of the pump (14) is fixedly connected to a valve (15), and an output end of the pump (14) is connected to the water distributor (16) through a pipeline.

6. The spray drying device for chemical pharmaceuticals according to claim 3, characterized in that: An electric heating fan (12) is fixedly mounted on the top of the cover plate (11), and an output end of the electric heating fan (12) is connected to an injection hole on one side of the cover plate (11) close to the rectangular mounting hole (1102) through a pipeline.

7. The spray drying device for chemical pharmaceuticals according to claim 1, characterized in that: Two groups of support legs (2) are symmetrically and fixedly connected to the outer peripheral surface of the conical core tank (1), and the bottom ends of the two support legs (2) are fixedly connected to a bottom plate (201).

8. The spray drying device for chemical pharmaceuticals according to claim 1, characterized in that: The outer peripheral surface of the grinding roller (7) is provided with grinding grooves (701) at equal intervals, and the depth of the grinding grooves (701) is one millimeter.

Citation Information

Patent Citations

  • Spray drying device for chemical pharmacy

    CN219272160U