Diluting device for glycopyrronium bromide neostigmine injection

Abstract

The utility model relates to the technical field of dilution preparation of injection, in particular to a dilution preparation device for glycopyrronium bromide neostigmine injection, which comprises a tank body, a tank cover is arranged at the top of the tank body, a sealing plate is arranged at the joint of the tank body and the tank cover, a first motor is arranged at the top of the tank cover, the output end of the first motor is fixedly connected with a rotating rod, and the rotating rod is fixedly connected with the tank cover. A plurality of lantern rings are arranged on the outer side of the rotating rod, stirring plates are symmetrically arranged on the outer sides of the lantern rings, and feeding nozzles are arranged between the lantern rings. The first motor drives the rotating rod to rotate, the rotating rod rotates to drive the lantern ring and the stirring plate to rotate together, and the stirring plate can be more conveniently detached through the lantern ring, so that the stirring plate is replaced and maintained; the first motor is used for driving the stirring plate to rotate at a low speed, so that injection in the tank body and diluent in the feeding box are stirred and mixed, and meanwhile, other diluent with a small dosage is added through the feeding spray head in the rotating rod.

Description

Technical Field

[0001] This utility model relates to the field of dilution preparation technology for injectable solutions, and in particular to a dilution preparation device for neostigmine bromide injectable solution. Background Technology

[0002] Glyceryl sulfonylurea (GSP) and neostigmine injection is a drug primarily used clinically to treat Alzheimer's disease and other neurodegenerative diseases. It combines two active ingredients: glycopyrronium bromide and neostigmine, each with different mechanisms of action that work synergistically. The combined action of glycopyrronium bromide and neostigmine enhances acetylcholine function, improving cognitive impairment or neuromuscular transmission problems caused by neurodegenerative diseases. The combination of glycopyrronium bromide and neostigmine provides greater cardiac stability than neostigmine alone. Furthermore, due to the limited penetration of glycopyrronium bromide into the central nervous system, residual central anticholinergic effects are minimized. It is primarily used to treat diseases such as Alzheimer's disease.

[0003] Existing technologies mostly involve manually extracting and diluting the drug solution, which is prone to contamination and therefore does not meet current needs. Utility Model Content

[0004] This utility model addresses the shortcomings of existing technologies by providing the following technical solution:

[0005] A dilution device for glycopyrronium bromide neostigmine injection includes a tank body, a tank cover at the top of the tank body, a sealing plate at the connection between the tank body and the tank cover, a first motor at the top of the tank cover, a rotating rod fixedly connected to the output end of the first motor, a plurality of collars on the outer side of the rotating rod, stirring plates symmetrically arranged on the outer side of the collars, a feeding nozzle between the collars, and a pH value detection element at the top of the rotating rod.

[0006] As an improvement to the above technical solution, a first connecting pipe is provided on the outside of the tank, a first valve is provided at the other end of the first connecting pipe, and a feeding box is fixedly connected to the other end of the first valve.

[0007] As an improvement to the above technical solution, a second valve is fixedly connected to the outside of the tank. A second connecting pipe is provided at one end of the second valve, and a oscillation box is provided at the other end of the second connecting pipe. A third connecting pipe is provided on one side of the oscillation box. A first support frame is rotatably connected to one bottom end of the oscillation box, and an oscillation component is provided at the other bottom end of the oscillation box.

[0008] As an improvement to the above technical solution, the oscillation assembly includes a connecting plate fixedly connected to the bottom of the oscillation box. A sliding groove is provided on the top of the connecting plate, and a sliding rod is slidably connected in the sliding groove. The sliding rod is fixedly connected to the top of the turntable, and the turntable is fixedly connected to the output end of the second motor. A fixing rod is rotatably connected to one end of the connecting plate.

[0009] As an improvement to the above technical solution, the bottom end of the fixing rod is fixedly connected to the top of the second support frame, which is located below the turntable.

[0010] As an improvement to the above technical solution, a motor box is provided on the top of the can lid, a first motor is provided inside the motor box, and a filling port is provided at one end of the top of the can lid.

[0011] As an improvement to the above technical solution, the bottom of the tank is fixedly connected with several support legs.

[0012] The beneficial effects of this utility model are:

[0013] 1. The first motor drives the rotating rod to rotate, which in turn drives the collar and the stirring plate to rotate together. The collar makes it easier to disassemble the stirring plate for replacement and maintenance. The first motor drives the stirring plate to rotate slowly, thereby mixing the injection liquid in the tank with the diluent in the feeding tank. At the same time, a small amount of diluent is added through the feeding nozzle inside the rotating rod. This feeding method can make the diluent mix more evenly with the injection liquid.

[0014] 2. The second motor drives the turntable to rotate, which in turn drives the slide rod on top of it to rotate. When the slide rod moves in the groove in the connecting plate, since one end of the connecting plate is rotatably connected to the top of the second support frame through the fixed rod, the connecting plate will drive the vibration box connected to it to rotate at a certain angle. The vibration effect is achieved by slowly rotating back and forth. On the one hand, it can enhance the mixing effect, and on the other hand, it can reduce the generation of bubbles to a certain extent. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the structure of this utility model;

[0016] Figure 2 This is a schematic diagram of the internal structure of the tank in this utility model;

[0017] Figure 3 This is a schematic diagram of the oscillation component in this utility model.

[0018] Reference numerals: 1. Tank body; 2. Tank cover; 3. Sealing plate; 4. Inlet; 5. Feeding box; 6. First valve; 7. First connecting pipe; 8. Motor box; 9. Support leg; 10. Second valve; 11. Second connecting pipe; 12. Vibration box; 13. First support frame; 14. Second support frame; 15. First motor; 16. Rotating rod; 17. Collar; 18. Stirring plate; 19. Feeding nozzle; 20. Connecting plate; 21. Slide groove; 22. Slide rod; 23. Turntable; 24. Second motor; 25. Third connecting pipe; 26. Fixing rod; 27. pH value detection element. Detailed Implementation

[0019] To make the objectives, technical solutions, and advantages of this utility model clearer, the following provides a more detailed description of the utility model. It should be understood that the specific embodiments described herein are merely illustrative and not intended to limit the scope of the utility model.

[0020] Please refer to Figures 1-3 A dilution device for neostigmine bromide injection includes a tank body 1, a tank cover 2 on the top of the tank body 1, a sealing plate 3 at the connection between the tank body 1 and the tank cover 2, a first motor 15 on the top of the tank cover 2, a rotating rod 16 fixedly connected to the output end of the first motor 15, a plurality of collars 17 on the outside of the rotating rod 16, stirring plates 18 symmetrically arranged on the outside of the collars 17, a feeding nozzle 19 between the collars 17, and a pH value detection element 27 at the top of the rotating rod 16.

[0021] Specifically, the canister 1 can be better sealed to the canister lid 2 through the sealing plate 3. The first motor 15 is started to drive the rotating rod 16 to rotate. The rotation of the rotating rod 16 will drive the collar 17 and the stirring plate 18 to rotate together. The collar 17 makes it easier to disassemble the stirring plate 18 for replacement and maintenance. The first motor 15 drives the stirring plate 18 to rotate slowly, thereby stirring and mixing the injection solution in the canister 1. At the same time, a small amount of diluent is added through the feeding nozzle 19 in the rotating rod 16. This feeding method can make the diluent mix more evenly with the injection solution. The pH value detection element 27 can detect the pH value of the injection solution to ensure that it is within the range required by the drug.

[0022] Please refer to Figures 1-3 A first connecting pipe 7 is provided on the outside of the tank body 1, and a first valve 6 is provided at the other end of the first connecting pipe 7. A feeding box 5 is fixedly connected to the other end of the first valve 6.

[0023] Specifically, the feeding box 5 contains a diluent mixed with the injection solution, and the flow is controlled by the first valve 6. The diluent flows into the tank 1 through the first connecting pipe 7. The connecting pipe is made of flexible material and can undergo a certain deformation without affecting its use.

[0024] Please refer to Figures 1-3 A second valve 10 is fixedly connected to the outside of the tank body 1. A second connecting pipe 11 is provided at one end of the second valve 10. A shaking box 12 is provided at the other end of the second connecting pipe 11. A third connecting pipe 25 is provided on one side of the shaking box 12. A first support frame 13 is rotatably connected to one end of the bottom of the shaking box 12. A shaking component is provided at the other end of the bottom of the shaking box 12.

[0025] Specifically, the injection solution after the first mixing can be controlled by the second valve 10 to enter the shaking box 12 through the second connecting pipe 11. The shaking box 12 can rotate at a certain angle on the top of the first support frame 13.

[0026] Please refer to Figures 1-3 The oscillation assembly includes a connecting plate 20 fixedly connected to the bottom of the oscillation box 12. A groove 21 is provided on the top of the connecting plate 20. A sliding rod 22 is slidably connected in the groove 21. The sliding rod 22 is fixedly connected to the top of the turntable 23. The turntable 23 is fixedly connected to the output end of the second motor 24. A fixing rod 26 is rotatably connected to one end of the connecting plate 20.

[0027] Specifically, the second motor 24 drives the turntable 23 to rotate, which in turn drives the slide rod 22 on its top to rotate together. When the slide rod 22 moves in the slide groove 21 in the connecting plate 20, the connecting plate 20 will be moved along with it.

[0028] Please refer to Figures 1-3 The bottom end of the fixing rod 26 is fixedly connected to the top of the second support frame 14, which is located below the turntable 23.

[0029] Specifically, since one end of the connecting plate 20 is rotatably connected to the top of the second support frame 14 via the fixing rod 26, the movement of the connecting plate 20 will become a rotation at a certain angle with the fixing rod 26 as the center. At the same time, the connecting plate 20 is fixedly connected to the oscillating box 12, so the oscillating box 12 will also rotate together. Thus, the oscillation effect is achieved by slowly rotating back and forth. On the one hand, secondary mixing can be carried out to enhance the mixing effect, and on the other hand, the generation of bubbles can be reduced to a certain extent.

[0030] Please refer to Figures 1-3 The top of the can lid 2 is provided with a motor box 8, and the first motor 15 is provided inside the motor box 8. The top end of the can lid 2 is provided with a filling port 4.

[0031] Specifically, the motor housing 8 is used to protect the first motor 15, and the injection port 4 is used to add injection liquid.

[0032] Please refer to Figures 1-3 Several support legs 9 are fixedly connected to the bottom of the tank body 1.

[0033] Specifically, the support leg 9 is a support component that supports and fixes the tank body 1.

[0034] The above embodiments are only used to illustrate the technical solution of this utility model, and are not intended to limit it.

Claims

1. A dilution apparatus for neostigmine bromide injection, comprising a tank (1), a lid (2) provided on the top of the tank (1), and a sealing plate (3) provided at the connection between the tank (1) and the lid (2), characterized in that: The top of the can lid (2) is provided with a first motor (15), the output end of the first motor (15) is fixedly connected to a rotating rod (16), a plurality of collars (17) are provided on the outside of the rotating rod (16), a stirring plate (18) is symmetrically provided on the outside of the collars (17), a feeding nozzle (19) is provided between the collars (17), and a pH value detection element (27) is provided at the top of the rotating rod (16).

2. The dilution apparatus for glycopyrronium bromide neostigmine injection according to claim 1, characterized in that: The outer side of the tank (1) is provided with a first connecting pipe (7), and the other end of the first connecting pipe (7) is provided with a first valve (6), and the other end of the first valve (6) is fixedly connected to a feeding box (5).

3. The dilution apparatus for glycopyrronium bromide neostigmine injection according to claim 1, characterized in that: A second valve (10) is fixedly connected to the outside of the tank (1). A second connecting pipe (11) is provided at one end of the second valve (10). A oscillating box (12) is provided at the other end of the second connecting pipe (11). A third connecting pipe (25) is provided on one side of the oscillating box (12). A first support frame (13) is rotatably connected to one end of the bottom of the oscillating box (12). An oscillation assembly is provided at the other end of the bottom of the oscillating box (12).

4. The dilution apparatus for glycopyrronium bromide neostigmine injection according to claim 3, characterized in that: The oscillation assembly includes a connecting plate (20) fixedly connected to the bottom of the oscillation box (12). The top of the connecting plate (20) is provided with a sliding groove (21). A sliding rod (22) is slidably connected in the sliding groove (21). The sliding rod (22) is fixedly connected to the top of the turntable (23). The turntable (23) is fixedly connected to the output end of the second motor (24). A fixing rod (26) is rotatably connected to one end of the connecting plate (20).

5. The dilution apparatus for glycopyrronium bromide neostigmine injection according to claim 4, characterized in that: The bottom end of the fixing rod (26) is fixedly connected to the top of the second support frame (14), which is located below the turntable (23).

6. The dilution apparatus for glycopyrronium bromide neostigmine injection according to claim 1, characterized in that: The top of the can lid (2) is provided with a motor box (8), and a first motor (15) is provided inside the motor box (8). A filling port (4) is provided at one end of the top of the can lid (2).

7. The dilution apparatus for glycopyrronium bromide neostigmine injection according to claim 1, characterized in that: The bottom of the tank (1) is fixedly connected with several support legs (9).

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